| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.111778 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0932675 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0910239 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0641312 |
| RASAL2 | RAS protein activator like 2 | 0.0561568 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0554009 |
| INTS6 | integrator complex subunit 6 | 0.0517859 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0496777 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0488227 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0467856 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0455315 |
| PALLD | palladin, cytoskeletal associated protein | 0.0454136 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0439947 |
| SQSTM1 | sequestosome 1 | 0.0437041 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0434169 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.042537 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.042209 |
| VCL | vinculin | 0.0420355 |
| NTN4 | netrin 4 | 0.0396632 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0380371 |
| SFTPA2 | surfactant protein A2 | 0.0365099 |
| GPC6 | glypican 6 | 0.0355732 |
| MYOF | myoferlin | 0.0353305 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0350935 |
| NXN | nucleoredoxin | 0.0349297 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0348524 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0346315 |
| AEBP2 | AE binding protein 2 | 0.034438 |
| SVIL | supervillin | 0.0340114 |
| GPATCH2L | G patch domain containing 2-like | 0.0340045 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0338876 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0331065 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0327506 |
| NRG1 | neuregulin 1 | 0.0320788 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.032015 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0315477 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0313779 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0309718 |
| STC2 | stanniocalcin 2 | 0.0308781 |
| RPS12 | ribosomal protein S12 | 0.0293921 |
| RAB10 | RAB10, member RAS oncogene family | 0.0292032 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0289977 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0288998 |
| ATF6 | activating transcription factor 6 | 0.0286852 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0285446 |
| HMGA2 | high mobility group AT-hook 2 | 0.0276561 |
| PDLIM5 | PDZ and LIM domain 5 | 0.027618 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0275604 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0275082 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0274476 |
| FHIT | fragile histidine triad | 0.0270991 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0266477 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0266456 |
| LYST | lysosomal trafficking regulator | 0.0265074 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0259038 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0254931 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0252833 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0252013 |
| OXR1 | oxidation resistance 1 | 0.0250623 |
| SEPTIN9 | septin 9 | 0.0249777 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0245735 |
| DUSP16 | dual specificity phosphatase 16 | 0.0243531 |
| B2M | beta-2-microglobulin | 0.0242961 |
| ACTG1 | actin gamma 1 | 0.0242643 |
| ABLIM1 | actin binding LIM protein 1 | 0.0241891 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.024013 |
| ASPH | aspartate beta-hydroxylase | 0.0239132 |
| MCL1 | myeloid cell leukemia 1 | 0.0237934 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0232323 |
| S100A10 | S100 calcium binding protein A10 | 0.0228075 |
| SLC35F3 | solute carrier family 35, member F3 | 0.022623 |
| SDC2 | syndecan 2 | 0.0226183 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0223944 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0223879 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0222536 |
| UBAP2 | ubiquitin associated protein 2 | 0.022014 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0219856 |
| DSTN | destrin (actin depolymerizing factor) | 0.0219138 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0217879 |
| SIK3 | SIK family kinase 3 | 0.0217113 |
| RPL37 | ribosomal protein L37 | 0.0215863 |
| SIRT1 | sirtuin 1 | 0.021516 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0212601 |
| RACK1 | receptor for activated C kinase 1 | 0.0211814 |
| ENO1 | enolase 1, (alpha) | 0.0211676 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.021059 |
| RPS27 | ribosomal protein S27 | 0.0208301 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0207044 |
| RND3 | Rho family GTPase 3 | 0.020589 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0200906 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0199765 |
| CTSB | cathepsin B | 0.0195574 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0192749 |
| LOXL2 | lysyl oxidase-like 2 | 0.0189507 |
| RASEF | RAS and EF-hand domain containing | 0.018901 |
| ABR | active BCR-related | 0.0186056 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.018358 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.018292 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0181418 |
| JAK1 | Janus kinase 1 | 0.018123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.252775 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.130455 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.110564 |
| FN1 | fibronectin 1 | -0.0920517 |
| PTMA | prothymosin, alpha | -0.0914766 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.086917 |
| CANX | calnexin | -0.0856287 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.079464 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0792422 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0743578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0735463 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0674806 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0593058 |
| COPA | coatomer protein complex, subunit alpha | -0.055423 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0542722 |
| RBM39 | RNA binding motif protein 39 | -0.0541593 |
| RNF145 | ring finger protein 145 | -0.0508204 |
| CENPF | centromere protein F, 350/400kDa | -0.0504003 |
| TMSB10 | thymosin beta 10 | -0.0473398 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0444601 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0441331 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0440706 |
| RBM25 | RNA binding motif protein 25 | -0.0437344 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0434346 |
| TPR | translocated promoter region, nuclear basket protein | -0.0428538 |
| SUCO | SUN domain containing ossification factor | -0.0417313 |
| OGA | O-GlcNAcase | -0.0412491 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0395906 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0392501 |
| CALR | calreticulin | -0.0391174 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.039045 |
| S100A6 | S100 calcium binding protein A6 | -0.0385782 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0376955 |
| PKM | pyruvate kinase, muscle | -0.0376224 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.037613 |
| TMSB4X | thymosin beta 4, X-linked | -0.0375979 |
| TFG | TRK-fused gene | -0.0370559 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0369982 |
| GOLGA4 | golgin A4 | -0.0369736 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0367956 |
| WDR45B | WD repeat domain 45B | -0.0356747 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0355166 |
| ZNF292 | zinc finger protein 292 | -0.0354129 |
| RUNX2 | runt-related transcription factor 2 | -0.0349729 |
| ETV6 | ets variant 6 | -0.0339448 |
| VEGFA | vascular endothelial growth factor A | -0.0339074 |
| HMGB3 | high mobility group box 3 | -0.033907 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0337239 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0335383 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0334822 |
| CDC27 | cell division cycle 27 | -0.0332624 |
| NUP58 | nucleoporin 58 | -0.0331361 |
| SYT1 | synaptotagmin I | -0.03292 |
| CDC73 | cell division cycle 73 | -0.032885 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0327999 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0327546 |
| SPAG9 | sperm associated antigen 9 | -0.0325728 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0319188 |
| HELZ | helicase with zinc finger | -0.0316448 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0312784 |
| RRBP1 | ribosome binding protein 1 | -0.0312298 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0312022 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0310763 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0308552 |
| NRP1 | neuropilin 1 | -0.030711 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0300356 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0295375 |
| PGK1 | phosphoglycerate kinase 1 | -0.0295126 |
| CLINT1 | clathrin interactor 1 | -0.0294216 |
| CD44 | CD44 molecule (Indian blood group) | -0.0293663 |
| TXNIP | thioredoxin interacting protein | -0.0290528 |
| FNBP1 | formin binding protein 1 | -0.0290009 |
| NEK7 | NIMA-related kinase 7 | -0.0288444 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0287184 |
| ETV1 | ets variant 1 | -0.0286478 |
| ARF4 | ADP-ribosylation factor 4 | -0.0283948 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.027678 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0276445 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0275885 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0275826 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0273605 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0272419 |
| HDLBP | high density lipoprotein binding protein | -0.0272047 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0271939 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0270426 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0269319 |
| FAM20C | family with sequence similarity 20, member C | -0.026696 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0265759 |
| INSIG2 | insulin induced gene 2 | -0.026394 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0261481 |
| MKI67 | marker of proliferation Ki-67 | -0.0260384 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0256979 |
| RAD21 | RAD21 homolog (S. pombe) | -0.025534 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0252663 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0250103 |
| AHR | aryl hydrocarbon receptor | -0.0249841 |
| CLTC | clathrin, heavy chain (Hc) | -0.0246078 |
| COG5 | component of oligomeric golgi complex 5 | -0.0245873 |
| OSMR | oncostatin M receptor | -0.0245263 |
| USP3 | ubiquitin specific peptidase 3 | -0.02441 |
