| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 9-ING-41_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NEBL | nebulette | 0.100404 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0797629 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0761017 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0750281 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0646131 |
| JMJD1C | jumonji domain containing 1C | 0.0560127 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0541905 |
| MYO1E | myosin IE | 0.0517488 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0512724 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0500495 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0497853 |
| MED13L | mediator complex subunit 13-like | 0.0488208 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0471382 |
| RPS21 | ribosomal protein S21 | 0.0448912 |
| RPS6 | ribosomal protein S6 | 0.0445132 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0424063 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0421609 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0414189 |
| RPL35A | ribosomal protein L35a | 0.0405448 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0403084 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0398237 |
| TPX2 | TPX2, microtubule-associated | 0.0373238 |
| MKI67 | marker of proliferation Ki-67 | 0.0372589 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0372005 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0370362 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0362829 |
| DOCK4 | dedicator of cytokinesis 4 | 0.03605 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0355157 |
| VCL | vinculin | 0.0353624 |
| NEK7 | NIMA-related kinase 7 | 0.0352279 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0351256 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0345807 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0343352 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0340954 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0340481 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0338237 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0337816 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0333675 |
| SIK3 | SIK family kinase 3 | 0.0333491 |
| DSPP | dentin sialophosphoprotein | 0.0329386 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.032919 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0328939 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0327346 |
| NCKAP1 | NCK-associated protein 1 | 0.0327287 |
| RPL34 | ribosomal protein L34 | 0.0324012 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0321667 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0321503 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0317642 |
| RPS2 | ribosomal protein S2 | 0.0313695 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0311128 |
| KRT20 | keratin 20, type I | 0.0310483 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0305357 |
| H1-0 | H1.0 linker histone | 0.0301239 |
| ANKRD12 | ankyrin repeat domain 12 | 0.029777 |
| TRIM2 | tripartite motif containing 2 | 0.0296192 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0293024 |
| ERBIN | erbb2 interacting protein | 0.0291998 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0289991 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0288192 |
| EPCAM | epithelial cell adhesion molecule | 0.0286141 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284326 |
| MALT1 | MALT1 paracaspase | 0.0281988 |
| USP6NL | USP6 N-terminal like | 0.0281219 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0279848 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0278676 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0278463 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.027788 |
| RPL23 | ribosomal protein L23 | 0.0277097 |
| OXR1 | oxidation resistance 1 | 0.0275708 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0269921 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0268728 |
| TXNRD1 | thioredoxin reductase 1 | 0.0266695 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0265831 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0262989 |
| CREBBP | CREB binding protein | 0.0262967 |
| CD2AP | CD2-associated protein | 0.0261984 |
| RPLP1 | ribosomal protein, large, P1 | 0.0259313 |
| SBF2 | SET binding factor 2 | 0.0258594 |
| ZNRF3 | zinc and ring finger 3 | 0.0258425 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0253722 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0253391 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.025133 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0250924 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0250284 |
| ETV6 | ets variant 6 | 0.0249012 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0248815 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0248439 |
| SERINC5 | serine incorporator 5 | 0.0244676 |
| RND3 | Rho family GTPase 3 | 0.0244279 |
| JUN | jun proto-oncogene | 0.0243346 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0243337 |
| SVIL | supervillin | 0.024238 |
| COG5 | component of oligomeric golgi complex 5 | 0.0241474 |
| RPL26 | ribosomal protein L26 | 0.0239698 |
| TJP1 | tight junction protein 1 | 0.0238978 |
| YAP1 | Yes-associated protein 1 | 0.0238267 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0237867 |
| CREBRF | CREB3 regulatory factor | 0.0236479 |
| SNX9 | sorting nexin 9 | 0.0236463 |
| BPTF | bromodomain PHD finger transcription factor | 0.0234957 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.18898 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.14333 |
| EGR1 | early growth response 1 | -0.114686 |
| PTMA | prothymosin, alpha | -0.108884 |
| NDRG1 | N-myc downstream regulated 1 | -0.0998853 |
| TMSB10 | thymosin beta 10 | -0.0989736 |
| LDHA | lactate dehydrogenase A | -0.0901893 |
| PKM | pyruvate kinase, muscle | -0.0799383 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0742611 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0701087 |
| FAT1 | FAT atypical cadherin 1 | -0.06891 |
| HLA-A | major histocompatibility complex, class I, A | -0.0676662 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0673352 |
| KRT18 | keratin 18, type I | -0.0634289 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0583485 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0581948 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0548943 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0528953 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0510855 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0497853 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.049183 |
| FOSL1 | FOS-like antigen 1 | -0.04539 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0453333 |
| PERP | PERP, TP53 apoptosis effector | -0.0447961 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0446998 |
| ITGB4 | integrin, beta 4 | -0.0445123 |
| HMGA1 | high mobility group AT-hook 1 | -0.0431633 |
| KRT8 | keratin 8, type II | -0.0422075 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0399313 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0366334 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0365769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0353254 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.035271 |
| CST3 | cystatin C | -0.0339855 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0327683 |
| MXD1 | MAX dimerization protein 1 | -0.0318898 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0317321 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0315304 |
| PGK1 | phosphoglycerate kinase 1 | -0.0311658 |
| CTSD | cathepsin D | -0.030866 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0308502 |
| S100A10 | S100 calcium binding protein A10 | -0.0307559 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0305908 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0305295 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0304668 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0304607 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0301494 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0300726 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0298832 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0295765 |
| VEGFA | vascular endothelial growth factor A | -0.0292425 |
| TPM4 | tropomyosin 4 | -0.0290237 |
| SCG2 | secretogranin II | -0.0289386 |
| PFN1 | profilin 1 | -0.0284633 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0280008 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0277966 |
| NFIA | nuclear factor I/A | -0.02768 |
| CCND1 | cyclin D1 | -0.0276233 |
| CLDN4 | claudin 4 | -0.0272279 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0271762 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0267935 |
| TOB1 | transducer of ERBB2, 1 | -0.0267749 |
| EXOC4 | exocyst complex component 4 | -0.0267177 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0265157 |
| INTS6 | integrator complex subunit 6 | -0.0264612 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0263613 |
| STC2 | stanniocalcin 2 | -0.0262508 |
| YBX1 | Y box binding protein 1 | -0.0261558 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0259788 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0257538 |
| TPI1 | triosephosphate isomerase 1 | -0.0256995 |
| TMEM123 | transmembrane protein 123 | -0.0256272 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.0256188 |
| BSG | basigin (Ok blood group) | -0.0255911 |
| ACTN4 | actinin, alpha 4 | -0.0255828 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0250798 |
| CPLX2 | complexin 2 | -0.0247985 |
| HM13 | histocompatibility (minor) 13 | -0.0241299 |
| JUP | junction plakoglobin | -0.0240641 |
| POTEF | POTE ankyrin domain family, member F | -0.0239356 |
| FTL | ferritin, light polypeptide | -0.0234828 |
| ITGA6 | integrin, alpha 6 | -0.0233989 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0230919 |
| CLDN3 | claudin 3 | -0.0230731 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0224322 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -0.0223153 |
| L1CAM | L1 cell adhesion molecule | -0.0213687 |
| DENND1A | DENN/MADD domain containing 1A | -0.0210199 |
| S100A6 | S100 calcium binding protein A6 | -0.0208803 |
| RYBP | RING1 and YY1 binding protein | -0.0208316 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0207979 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0206347 |
| SETX | senataxin | -0.0205596 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0203352 |
| EP400 | E1A binding protein p400 | -0.0203035 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0202299 |
| RUNX1 | runt-related transcription factor 1 | -0.0200345 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.019996 |
| FMNL2 | formin-like 2 | -0.0199556 |
| SLTM | SAFB-like, transcription modulator | -0.0199411 |
