| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 9-ING-41 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 9-ING-41_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.391945 |
| HMGA2 | high mobility group AT-hook 2 | 0.236324 |
| INHBA | inhibin, beta A | 0.222482 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.141086 |
| MT2A | metallothionein 2A | 0.131291 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.127434 |
| VIM | vimentin | 0.126271 |
| FN1 | fibronectin 1 | 0.113246 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.100991 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0882097 |
| MMP1 | matrix metallopeptidase 1 | 0.0845539 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.083263 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0790875 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0687768 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.066883 |
| CD44 | CD44 molecule (Indian blood group) | 0.0668045 |
| DNER | delta/notch-like EGF repeat containing | 0.0608969 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0573044 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0560107 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0537138 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0526118 |
| MYO10 | myosin X | 0.0508758 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0507449 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0488168 |
| ASPH | aspartate beta-hydroxylase | 0.0482207 |
| RPS12 | ribosomal protein S12 | 0.0467462 |
| FOXP1 | forkhead box P1 | 0.0443643 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0439644 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0422876 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0418523 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0414924 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.040274 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0389847 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0387916 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.038722 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.038543 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0384379 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0380177 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0380087 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0378142 |
| AHNAK | AHNAK nucleoprotein | 0.0371092 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0371057 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0370893 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0367764 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0356846 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0349577 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0344789 |
| GLIS3 | GLIS family zinc finger 3 | 0.0344644 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0331466 |
| SQSTM1 | sequestosome 1 | 0.0329232 |
| FRMD4A | FERM domain containing 4A | 0.031669 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0313045 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0312462 |
| RPS3 | ribosomal protein S3 | 0.0311509 |
| HLA-B | major histocompatibility complex, class I, B | 0.031112 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0310393 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0305736 |
| B2M | beta-2-microglobulin | 0.0304791 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0302112 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.030172 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0297356 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0295337 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0289037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0286005 |
| HDAC9 | histone deacetylase 9 | 0.0283766 |
| INTS6 | integrator complex subunit 6 | 0.0280699 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0278712 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0276409 |
| CDK14 | cyclin-dependent kinase 14 | 0.0274916 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.027332 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0268729 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0263277 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0260691 |
| DST | dystonin | 0.0260652 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0255755 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0254249 |
| RAI14 | retinoic acid induced 14 | 0.0252926 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249334 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.024379 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0238698 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.023834 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0234668 |
| EMP1 | epithelial membrane protein 1 | 0.0232233 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0228096 |
| NOTCH2 | notch 2 | 0.0226059 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0225692 |
| SNX9 | sorting nexin 9 | 0.0222208 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0221421 |
| EGFR | epidermal growth factor receptor | 0.0220171 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0219123 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0219008 |
| SPAG9 | sperm associated antigen 9 | 0.0218409 |
| RUNX1 | runt-related transcription factor 1 | 0.0214177 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0211837 |
| NPTX1 | neuronal pentraxin I | 0.0208834 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0206812 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0205881 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0204555 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0203539 |
| RPS8 | ribosomal protein S8 | 0.0202006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.136458 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.115673 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.108991 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0961435 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0905271 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0787406 |
| FTL | ferritin, light polypeptide | -0.0648295 |
| GOLGA4 | golgin A4 | -0.0633322 |
| PTMA | prothymosin, alpha | -0.059615 |
| TMSB10 | thymosin beta 10 | -0.0585808 |
| NDRG1 | N-myc downstream regulated 1 | -0.0528615 |
| COL1A2 | collagen, type I, alpha 2 | -0.0524342 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0496448 |
| SETD5 | SET domain containing 5 | -0.0442255 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0428721 |
| RPL35A | ribosomal protein L35a | -0.0417721 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0406625 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0388713 |
| FAM13A | family with sequence similarity 13, member A | -0.0375836 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0370356 |
| ACTG1 | actin gamma 1 | -0.0345138 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0335336 |
| S100A6 | S100 calcium binding protein A6 | -0.0309336 |
| HELZ | helicase with zinc finger | -0.030499 |
| TPM4 | tropomyosin 4 | -0.0302217 |
| RPS16 | ribosomal protein S16 | -0.0295629 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.029109 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0286276 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0281524 |
| PKM | pyruvate kinase, muscle | -0.0279695 |
| VEGFA | vascular endothelial growth factor A | -0.0277344 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0274396 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0273679 |
| LOXL2 | lysyl oxidase-like 2 | -0.0273194 |
| POTEF | POTE ankyrin domain family, member F | -0.0262564 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0262464 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0262215 |
| CALD1 | caldesmon 1 | -0.0257072 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0251251 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0248575 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0248427 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0245865 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0240462 |
| NUP58 | nucleoporin 58 | -0.0237288 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0237021 |
| TMEM165 | transmembrane protein 165 | -0.0236545 |
| RPS24 | ribosomal protein S24 | -0.0236173 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234474 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0232483 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0227852 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0227002 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0224185 |
| RPS13 | ribosomal protein S13 | -0.0223776 |
| RNF145 | ring finger protein 145 | -0.0220115 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0218643 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0214794 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0213074 |
| SEPTIN2 | septin 2 | -0.0212912 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0211493 |
| RPLP1 | ribosomal protein, large, P1 | -0.0210596 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0210457 |
| MSI2 | musashi RNA-binding protein 2 | -0.0207674 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0207219 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0203978 |
| MORF4L2 | mortality factor 4 like 2 | -0.0203656 |
| SRP54 | signal recognition particle 54kDa | -0.0203578 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0198226 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0196111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0194659 |
| SEC24A | SEC24 family member A | -0.0193332 |
| ARF4 | ADP-ribosylation factor 4 | -0.0193123 |
| NGLY1 | N-glycanase 1 | -0.0192959 |
| HM13 | histocompatibility (minor) 13 | -0.0192823 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0192231 |
| TXNRD1 | thioredoxin reductase 1 | -0.0192145 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0191691 |
| PER1 | period circadian clock 1 | -0.0191672 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0191565 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0191419 |
| RPLP2 | ribosomal protein, large, P2 | -0.019081 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0189845 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0188416 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0185093 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0184885 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0184107 |
| RPL31 | ribosomal protein L31 | -0.0184019 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0183711 |
| GOLGB1 | golgin B1 | -0.018321 |
| UBC | ubiquitin C | -0.0182625 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0182195 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0182187 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0181244 |
| WDR45B | WD repeat domain 45B | -0.0180982 |
| NKTR | natural killer cell triggering receptor | -0.0180687 |
| CCNL1 | cyclin L1 | -0.0180371 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0179365 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.017871 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.017823 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0178117 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0176546 |
