A549_Alendronate sodium trihydrate_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Alendronate sodium trihydrate 1µM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
Similar Terms
Downloads & Tools

Genes

1000 genes differentially expressed following the A549_Alendronate sodium trihydrate_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.246102
CA12 carbonic anhydrase XII 0.182943
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.166875
FTL ferritin, light polypeptide 0.150412
PKM pyruvate kinase, muscle 0.1292
KRT81 keratin 81, type II 0.123778
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.116519
AKAP12 A kinase (PRKA) anchor protein 12 0.093481
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0929267
MAP1B microtubule-associated protein 1B 0.0910166
RPL15 ribosomal protein L15 0.0610701
BSG basigin (Ok blood group) 0.0587621
ANXA1 annexin A1 0.0512333
BAIAP2L1 BAI1-associated protein 2-like 1 0.0507553
TPI1 triosephosphate isomerase 1 0.0494493
MYO1E myosin IE 0.0490627
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0490375
UBL4A ubiquitin-like 4A 0.0483553
TMSB10 thymosin beta 10 0.0474827
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0470369
MYADM myeloid-associated differentiation marker 0.0415202
RPS8 ribosomal protein S8 0.041499
NRG1 neuregulin 1 0.0398164
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0397207
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0393275
AGR2 anterior gradient 2 0.039002
EML4 echinoderm microtubule associated protein like 4 0.0386974
AKR1C3 aldo-keto reductase family 1, member C3 0.0385996
ASPH aspartate beta-hydroxylase 0.0347176
SUMF1 sulfatase modifying factor 1 0.0342796
RPLP0 ribosomal protein, large, P0 0.0342215
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0340859
CAVIN1 caveolae associated protein 1 0.0336164
OPHN1 oligophrenin 1 0.0332986
LRP10 low density lipoprotein receptor-related protein 10 0.033151
S100A6 S100 calcium binding protein A6 0.0330487
FAM107B family with sequence similarity 107, member B 0.0328605
DUSP16 dual specificity phosphatase 16 0.0327072
FDPS farnesyl diphosphate synthase 0.0322309
RNF38 ring finger protein 38 0.0317326
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0313011
CHD3 chromodomain helicase DNA binding protein 3 0.0311892
RGS17 regulator of G-protein signaling 17 0.0309808
ARL4C ADP-ribosylation factor-like 4C 0.0305503
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0295755
REXO2 RNA exonuclease 2 0.0295351
DGKD diacylglycerol kinase, delta 130kDa 0.0291279
PRPF8 pre-mRNA processing factor 8 0.0286075
EREG epiregulin 0.0285361
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.0283927
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0281816
AKR1C2 aldo-keto reductase family 1, member C2 0.0279558
MTPN myotrophin 0.0279115
RTN4 reticulon 4 0.0277659
ZFHX3 zinc finger homeobox 3 0.0277595
RPLP2 ribosomal protein, large, P2 0.0274376
TRIP12 thyroid hormone receptor interactor 12 0.0274245
CD81 CD81 molecule 0.0268154
RPLP1 ribosomal protein, large, P1 0.0265696
RPL28 ribosomal protein L28 0.026524
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0265093
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0264066
ZBTB38 zinc finger and BTB domain containing 38 0.0263999
CLIP1 CAP-GLY domain containing linker protein 1 0.0263984
LOC112694756 uncharaterized LOC112694756 0.0263662
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.0262688
ACOT7 acyl-CoA thioesterase 7 0.0261182
KRT7 keratin 7, type II 0.0255921
ENO1 enolase 1, (alpha) 0.0254499
ACTN4 actinin, alpha 4 0.0253414
SCAF11 SR-related CTD-associated factor 11 0.0252504
RPL13A ribosomal protein L13a 0.0252283
ERRFI1 ERBB receptor feedback inhibitor 1 0.0249785
C1RL complement component 1, r subcomponent-like 0.0248242
TRIM28 tripartite motif containing 28 0.0247586
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0246755
PTMS parathymosin 0.0245829
GRAMD1B GRAM domain containing 1B 0.0245369
MCU mitochondrial calcium uniporter 0.0244515
APTX aprataxin 0.0243872
SMOX spermine oxidase 0.0241707
RPS5 ribosomal protein S5 0.0241618
JUP junction plakoglobin 0.0240709
PTGR1 prostaglandin reductase 1 0.0239361
MVP major vault protein 0.0237416
PA2G4 proliferation-associated 2G4, 38kDa 0.0236721
SH3PXD2A SH3 and PX domains 2A 0.0236017
G6PC3 glucose 6 phosphatase, catalytic, 3 0.0234239
MINK1 misshapen-like kinase 1 0.0233813
TPM2 tropomyosin 2 (beta) 0.0233603
ANXA2 annexin A2 0.0233339
SLC35F5 solute carrier family 35, member F5 0.0232033
PRKCA protein kinase C, alpha 0.0231472
FTH1 ferritin, heavy polypeptide 1 0.0230129
PITPNA phosphatidylinositol transfer protein, alpha 0.0229173
ABHD12 abhydrolase domain containing 12 0.0228557
PDLIM5 PDZ and LIM domain 5 0.0227472
METTL8 methyltransferase like 8 0.0227015
MPZL1 myelin protein zero-like 1 0.0225371
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.02253
DSCAM Down syndrome cell adhesion molecule 0.0224222
LIMCH1 LIM and calponin homology domains 1 0.0223519
CST3 cystatin C 0.0223162
RPL38 ribosomal protein L38 0.0222179
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0221622
GDI2 GDP dissociation inhibitor 2 0.0220927
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.0220207
PLXNA2 plexin A2 0.0218995
RHOA ras homolog family member A 0.021875
ENOSF1 enolase superfamily member 1 0.0218639
SMAD2 SMAD family member 2 0.0218036
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 0.0217558
IPO7 importin 7 0.0217271
RPL8 ribosomal protein L8 0.0215908
KRT19 keratin 19, type I 0.0213544
PYGB phosphorylase, glycogen; brain 0.0213158
LGALS1 lectin, galactoside-binding, soluble, 1 0.0212651
UGDH UDP-glucose 6-dehydrogenase 0.0211254
BMP6 bone morphogenetic protein 6 0.0211224
RPS2 ribosomal protein S2 0.0211015
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.0210956
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0210723
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0209269
ENAH enabled homolog (Drosophila) 0.0207628
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0207255
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0206833
ABLIM1 actin binding LIM protein 1 0.0206579
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.0205772
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0205512
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0201545
LCOR ligand dependent nuclear receptor corepressor 0.0201443
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0201159
KHDC4 KH domain containing 4, pre-mRNA splicing factor 0.0201061
FAM193A family with sequence similarity 193, member A 0.0201054
BTN3A3 butyrophilin, subfamily 3, member A3 0.0200357
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0200305
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0200274
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0198702
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.019839
ATXN1 ataxin 1 0.0197602
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 0.0197137
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.0196267
NHSL1 NHS-like 1 0.0195969
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0195573
FAM222B family with sequence similarity 222, member B 0.0195101
RACK1 receptor for activated C kinase 1 0.0194271
MYO5A myosin VA (heavy chain 12, myoxin) 0.0193349
MYEOV myeloma overexpressed 0.0192197
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.018974
ACLY ATP citrate lyase 0.0189157
FKBP15 FK506 binding protein 15, 133kDa 0.0188472
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0188444
AGO3 argonaute RISC catalytic component 3 0.0188289
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0187676
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0187659
TAGLN2 transgelin 2 0.018677
BZW2 basic leucine zipper and W2 domains 2 0.0185972
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0185895
NIBAN2 niban apoptosis regulator 2 0.018585
BAG1 BCL2-associated athanogene 0.0185496
WASF2 WAS protein family, member 2 0.0184836
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0184679
RDH10 retinol dehydrogenase 10 (all-trans) 0.0184284
FKBP3 FK506 binding protein 3, 25kDa 0.0184148
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.0183992
CLMN calmin (calponin-like, transmembrane) 0.0183876
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.018367
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.0183236
TTC19 tetratricopeptide repeat domain 19 0.0183049
UIMC1 ubiquitin interaction motif containing 1 0.0183046
TRAPPC8 trafficking protein particle complex 8 0.0182262
KATNBL1 katanin p80 subunit B-like 1 0.0181878
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.0181818
AAK1 AP2 associated kinase 1 0.0180752
TOP2B topoisomerase (DNA) II beta 180kDa 0.0180467
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.017874
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0177649
CEP170 centrosomal protein 170kDa 0.0177316
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 0.0177114
ETV4 ets variant 4 0.0176388
ADAM9 ADAM metallopeptidase domain 9 0.0176304
CHLSN cholesin 0.0176032
MARK2 MAP/microtubule affinity-regulating kinase 2 0.017589
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.0175325
IL18 interleukin 18 0.0175135
EFR3A EFR3 homolog A (S. cerevisiae) 0.0174882
TMEM205 transmembrane protein 205 0.0174839
USP32 ubiquitin specific peptidase 32 0.0174519
HMGB1 high mobility group box 1 0.0174375
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.0174262
IQSEC2 IQ motif and Sec7 domain 2 0.0173878
AREG amphiregulin 0.0173245
IER5L immediate early response 5-like 0.0173196
LPIN1 lipin 1 0.0173184
GSE1 Gse1 coiled-coil protein 0.0171698
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.0170757
CCNY cyclin Y 0.0170279
EMP3 epithelial membrane protein 3 0.0169722
OAZ1 ornithine decarboxylase antizyme 1 0.0169486
SOX4 SRY (sex determining region Y)-box 4 0.0168746
TJP1 tight junction protein 1 0.0168714
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.016867
LUZP1 leucine zipper protein 1 0.01684
CBX5 chromobox homolog 5 0.0167574
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.0166117
MTMR9 myotubularin related protein 9 0.0165751
ARHGAP21 Rho GTPase activating protein 21 0.0165504
WDR33 WD repeat domain 33 0.0165267
JARID2 jumonji, AT rich interactive domain 2 0.0165205
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.0164936
DSTN destrin (actin depolymerizing factor) 0.01636
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0163183
JOSD2 Josephin domain containing 2 0.0162624
MRPS27 mitochondrial ribosomal protein S27 0.0162422
EHD2 EH-domain containing 2 0.0162195
GPC1 glypican 1 0.0161541
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0161536
GPX2 glutathione peroxidase 2 0.0161277
RASA2 RAS p21 protein activator 2 0.0160931
PBX3 pre-B-cell leukemia homeobox 3 0.0160852
RAI14 retinoic acid induced 14 0.0159943
RAB40C RAB40C, member RAS oncogene family 0.0159706
FAM13A family with sequence similarity 13, member A 0.0159675
CREB1 cAMP responsive element binding protein 1 0.0159188
RPS7 ribosomal protein S7 0.015887
GIPC1 GIPC PDZ domain containing family, member 1 0.0157903
ERLEC1 endoplasmic reticulum lectin 1 0.0156785
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0156364
DSTYK dual serine/threonine and tyrosine protein kinase 0.0156358
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0155935
SH3PXD2B SH3 and PX domains 2B 0.0155317
PDS5B PDS5 cohesin associated factor B 0.0155064
CDC123 cell division cycle 123 0.0154797
PRR11 proline rich 11 0.0154727
MAP2K2 mitogen-activated protein kinase kinase 2 0.0154588
AKR1C1 aldo-keto reductase family 1, member C1 0.0153192
RPS21 ribosomal protein S21 0.0153176
RPS14 ribosomal protein S14 0.0153119
TSPAN14 tetraspanin 14 0.0152638
KLF13 Kruppel-like factor 13 0.0152517
IPO9 importin 9 0.0152403
FXR1 fragile X mental retardation, autosomal homolog 1 0.0152131
C1ORF159 chromosome 1 open reading frame 159 0.0151772
RNASEH1 ribonuclease H1 0.0151387
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0151253
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.0150958
TUBB tubulin, beta class I 0.0150713
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0150417
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.0150322
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0150131
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0149795
PRMT3 protein arginine methyltransferase 3 0.014978
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0149536
RPS11 ribosomal protein S11 0.0148756
RPL18 ribosomal protein L18 0.0148606
TNPO1 transportin 1 0.0148362
PON3 paraoxonase 3 0.0148331
MRPS18B mitochondrial ribosomal protein S18B 0.0148141
PHF20L1 PHD finger protein 20-like 1 0.014805
RPS18 ribosomal protein S18 0.0147973
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.0147957
NBEAL1 neurobeachin-like 1 0.0147591
PLSCR1 phospholipid scramblase 1 0.0147553
UBASH3B ubiquitin associated and SH3 domain containing B 0.0147507
UEVLD UEV and lactate/malate dehyrogenase domains 0.0147224
HDAC1 histone deacetylase 1 0.0147135
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.0147135
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.014643
C2CD3 C2 calcium-dependent domain containing 3 0.0145931
ZNF146 zinc finger protein 146 0.0145841
CYBA cytochrome b-245, alpha polypeptide 0.0145514
WIPI2 WD repeat domain, phosphoinositide interacting 2 0.0145365
ELOB elongin B 0.0145327
CCM2 cerebral cavernous malformation 2 0.0145152
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.0144857
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0144812
ANKRD28 ankyrin repeat domain 28 0.0144258
RPS3 ribosomal protein S3 0.0144232
UBB ubiquitin B 0.0144059
WSB1 WD repeat and SOCS box containing 1 0.0143873
DMTN dematin actin binding protein 0.014378
SMOC1 SPARC related modular calcium binding 1 0.0143682
ATL3 atlastin GTPase 3 0.0143663
ZCCHC7 zinc finger, CCHC domain containing 7 0.014365
JAK1 Janus kinase 1 0.0143618
MORC2 MORC family CW-type zinc finger 2 0.0143476
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0143398
VASP vasodilator-stimulated phosphoprotein 0.014337
ABHD18 abhydrolase domain containing 18 0.0142863
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.0142812
ANAPC7 anaphase promoting complex subunit 7 0.0142603
HSF1 heat shock transcription factor 1 0.0142401
U2SURP U2 snRNP-associated SURP domain containing 0.0142379
ZFYVE1 zinc finger, FYVE domain containing 1 0.0142361
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.0142257
RHOB ras homolog family member B 0.0142154
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0141979
SLX4IP SLX4 interacting protein 0.0141863
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0141771
ITGB5 integrin, beta 5 0.0141746
ZRANB2 zinc finger, RAN-binding domain containing 2 0.0141501
IGFBP6 insulin-like growth factor binding protein 6 0.0141423
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0141376
TPM3 tropomyosin 3 0.0140947
JMJD1C jumonji domain containing 1C 0.0140942
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 0.0140881
RPL18A ribosomal protein L18a 0.0140126
HCFC1 host cell factor C1 0.0139993
TTC3 tetratricopeptide repeat domain 3 0.0139958
SET SET nuclear proto-oncogene 0.013976
PROCR protein C receptor, endothelial 0.0139719
TOM1L2 target of myb1-like 2 (chicken) 0.0139333
PEMT phosphatidylethanolamine N-methyltransferase 0.0139271
GPRIN3 GPRIN family member 3 0.0139028
SSH1 slingshot protein phosphatase 1 0.0138871
NICOL1 NELL2 interacting cell ontogeny regulator 1 0.0138847
TRIM9 tripartite motif containing 9 0.0138825
TM7SF3 transmembrane 7 superfamily member 3 0.0138781
HIPK3 homeodomain interacting protein kinase 3 0.0138745
MED19 mediator complex subunit 19 0.0138688
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0138509
MFSD11 major facilitator superfamily domain containing 11 0.0138494
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0138431
KLF6 Kruppel-like factor 6 0.0138226
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.0138176
PCNX1 pecanex 1 0.013795
INTS7 integrator complex subunit 7 0.0137518
MTMR1 myotubularin related protein 1 0.0137481
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0137396
MRPL19 mitochondrial ribosomal protein L19 0.0136782
BMPR1A bone morphogenetic protein receptor, type IA 0.0136579
CAPNS1 calpain, small subunit 1 0.0136566
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0136287
NEK4 NIMA-related kinase 4 0.0136158
TMEM97 transmembrane protein 97 0.0136139
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.0135813
SNX9 sorting nexin 9 0.0135715
HRNR hornerin 0.0135356
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.0135106
ZFP64 ZFP64 zinc finger protein 0.0134741
SERBP1 SERPINE1 mRNA binding protein 1 0.0134407
UBAC2 UBA domain containing 2 0.0134278
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 0.0134254
ODR4 odr-4 GPCR localization factor homolog 0.0134077
RETREG3 reticulophagy regulator family member 3 0.0133849
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0133846
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.0133723
S100A4 S100 calcium binding protein A4 0.013353
SP3 Sp3 transcription factor 0.0133355
AHCYL1 adenosylhomocysteinase-like 1 0.0133264
ARHGAP12 Rho GTPase activating protein 12 0.0132797
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0132314
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.0132176
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0132087
LDHA lactate dehydrogenase A 0.0131981
EFL1 elongation factor like GTPase 1 0.0131846
PLAAT3 phospholipase A and acyltransferase 3 0.0131736
SVIL supervillin 0.0131685
GUSB glucuronidase, beta 0.0131538
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.0131528
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 0.013145
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.0131368
WDFY1 WD repeat and FYVE domain containing 1 0.0130729
KMT2E lysine (K)-specific methyltransferase 2E 0.0130566
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 0.0130401
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.013033
ZZZ3 zinc finger, ZZ-type containing 3 0.0129889
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.0129878
GAN gigaxonin 0.0129843
CLIC4 chloride intracellular channel 4 0.0129817
RPGR retinitis pigmentosa GTPase regulator 0.0129815
CEP83 centrosomal protein 83kDa 0.0129742
HDGFL3 HDGF like 3 0.0129726
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.012966
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0129636
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.012959
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.0129542
ZNF367 zinc finger protein 367 0.0129531
PLD3 phospholipase D family, member 3 0.0129475
NUP133 nucleoporin 133kDa 0.0129397
NRF1 nuclear respiratory factor 1 0.0129123
RPS9 ribosomal protein S9 0.0129079
STK4 serine/threonine kinase 4 0.0128746
CDK12 cyclin-dependent kinase 12 0.0128714
RUVBL1 RuvB-like AAA ATPase 1 0.0128626
BCAP29 B-cell receptor-associated protein 29 0.0128489
CDKL5 cyclin-dependent kinase-like 5 0.0128354
PFKP phosphofructokinase, platelet 0.0128289
HILPDA hypoxia inducible lipid droplet-associated 0.0128099
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.0127912
COL4A4 collagen, type IV, alpha 4 0.0127832
TAOK1 TAO kinase 1 0.0127497
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0127485
ATP13A3 ATPase type 13A3 0.0127462
ZYX zyxin 0.0127088
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.012692
SLC38A10 solute carrier family 38, member 10 0.0126865
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.0126838
SCRN1 secernin 1 0.0126145
ANK2 ankyrin 2, neuronal 0.0126143
PMPCA peptidase (mitochondrial processing) alpha 0.0126136
CSNK1A1 casein kinase 1, alpha 1 0.0126084
ANKH ANKH inorganic pyrophosphate transport regulator 0.0126076
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.0125963
RBM41 RNA binding motif protein 41 0.0125716
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 0.0125595
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.0125252
USP53 ubiquitin specific peptidase 53 0.0125085
MDFIC MyoD family inhibitor domain containing 0.0124959
NF1 neurofibromin 1 0.012472
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.0124716
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.0124519
BRD2 bromodomain containing 2 0.0124498
SETD2 SET domain containing 2 0.0123922
PON2 paraoxonase 2 0.012388
SUMF2 sulfatase modifying factor 2 0.0123855
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 0.0123711
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.0123693
UCK2 uridine-cytidine kinase 2 0.0123436
TMED2 transmembrane emp24 domain trafficking protein 2 0.0123406
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.0123015
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0122818
CAPN1 calpain 1, (mu/I) large subunit 0.0122773
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0122636
FBXO9 F-box protein 9 0.0122389
CORO1B coronin, actin binding protein, 1B 0.0122324
ARRB2 arrestin, beta 2 0.0122317
RBPMS RNA binding protein with multiple splicing 0.0122303
ACSL4 acyl-CoA synthetase long-chain family member 4 0.0122285
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0122266
ACBD6 acyl-CoA binding domain containing 6 0.0122153
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 0.0122035
CD164 CD164 molecule, sialomucin 0.0121938
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.0121899
TUBA1A tubulin, alpha 1a 0.0121885
VCP valosin containing protein 0.0121731
RPS23 ribosomal protein S23 0.0121487
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 0.0121301
FADS2 fatty acid desaturase 2 0.0121301
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0121286
TSKU tsukushi, small leucine rich proteoglycan 0.0121285
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.0121213
FKBP10 FK506 binding protein 10, 65 kDa 0.0121205
NOTCH3 notch 3 0.0120952
PCLO piccolo presynaptic cytomatrix protein 0.012095
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0120892
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 0.012077
APOO apolipoprotein O 0.012077
PRR14L proline rich 14-like 0.012064
PHACTR4 phosphatase and actin regulator 4 0.0120522
PTEN phosphatase and tensin homolog 0.0120103
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.0120044
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0119879
HINT1 histidine triad nucleotide binding protein 1 0.0119706
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.0119568
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 0.0119559
TMEM248 transmembrane protein 248 0.0119417
KARS1 lysyl-tRNA synthetase 1 0.01192
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.0119168
FTO fat mass and obesity associated 0.0119063
RBM33 RNA binding motif protein 33 0.0118986
SANBR SANT and BTB domain regulator of CSR 0.0118759
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0118677
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.0118649
HABP4 hyaluronan binding protein 4 0.0118617
BCL9L B-cell CLL/lymphoma 9-like 0.0118518
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.0118481
FSTL4 follistatin-like 4 0.0118477
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 0.0118419
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0118414
TRAPPC1 trafficking protein particle complex 1 0.0118315
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.0118217
SEPTIN7 septin 7 0.0118119
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.0118058
KDM1A lysine (K)-specific demethylase 1A 0.0117462
CD24 CD24 molecule 0.0117389
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 0.0117348
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.0117336
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.0116923
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.0116879
TRIM27 tripartite motif containing 27 0.0116499
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 0.0116442
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.0116276
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0116142
FPGS folylpolyglutamate synthase 0.011571
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.0115626
RNF213 ring finger protein 213 0.011549
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 0.0115452
EIF3D eukaryotic translation initiation factor 3, subunit D 0.0115426
COA3 cytochrome c oxidase assembly factor 3 0.0115362
FBXO36 F-box protein 36 0.0115297
MSMO1 methylsterol monooxygenase 1 0.0115213
SEC62 SEC62 homolog (S. cerevisiae) 0.0115114
RABL6 RAB, member RAS oncogene family-like 6 0.0114732
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.0114587
TUT7 terminal uridylyl transferase 7 0.0114565
CEMIP cell migration inducing protein, hyaluronan binding 0.0114514
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0114449
BCAP31 B-cell receptor-associated protein 31 0.0114412
RPS4X ribosomal protein S4, X-linked 0.0114366

decreased expression

Symbol Name Standardized Value
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.145387
WWOX WW domain containing oxidoreductase -0.100553
TNS3 tensin 3 -0.0997559
MTUS1 microtubule associated tumor suppressor 1 -0.0996171
KRT8 keratin 8, type II -0.0937002
RAB10 RAB10, member RAS oncogene family -0.0858359
KRT18 keratin 18, type I -0.0831907
PCDH9 protocadherin 9 -0.0798482
PDE4D phosphodiesterase 4D, cAMP-specific -0.0758967
NFIA nuclear factor I/A -0.0729024
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0680102
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0671942
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0663583
TMOD3 tropomodulin 3 (ubiquitous) -0.0642727
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0614045
DAPK1 death-associated protein kinase 1 -0.0580603
PARD3 par-3 family cell polarity regulator -0.0578215
THSD7A thrombospondin, type I, domain containing 7A -0.0570578
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0564119
GRAMD1A GRAM domain containing 1A -0.0562458
CLU clusterin -0.0527462
SMYD3 SET and MYND domain containing 3 -0.0525208
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0519563
ZBTB20 zinc finger and BTB domain containing 20 -0.0509432
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0493068
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0491561
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.047813
USP34 ubiquitin specific peptidase 34 -0.0478118
SYT1 synaptotagmin I -0.0464803
CNTN1 contactin 1 -0.0461317
ARHGAP26 Rho GTPase activating protein 26 -0.0460735
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0456821
GLIS3 GLIS family zinc finger 3 -0.0455125
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0453358
FN1 fibronectin 1 -0.0451633
CMIP c-Maf inducing protein -0.0450309
EHBP1 EH domain binding protein 1 -0.0440342
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0439065
MKI67 marker of proliferation Ki-67 -0.0433949
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0427658
CENPF centromere protein F, 350/400kDa -0.0427353
TPM4 tropomyosin 4 -0.0424786
RORA RAR-related orphan receptor A -0.0400332
SPIDR scaffolding protein involved in DNA repair -0.04003
GLG1 golgi glycoprotein 1 -0.0392367
NT5C2 5'-nucleotidase, cytosolic II -0.0390002
MYOF myoferlin -0.0389601
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0386318
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0384459
RSF1 remodeling and spacing factor 1 -0.0384432
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0384028
WWC1 WW and C2 domain containing 1 -0.0378341
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0377493
ACTG1 actin gamma 1 -0.0372887
DENND5B DENN/MADD domain containing 5B -0.037026
RABGAP1L RAB GTPase activating protein 1-like -0.036647
MED13L mediator complex subunit 13-like -0.0366456
MYO10 myosin X -0.0364452
CTSD cathepsin D -0.0361828
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.0357044
GPC6 glypican 6 -0.0352609
AKAP13 A kinase (PRKA) anchor protein 13 -0.0352609
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0350511
PATJ PATJ crumbs cell polarity complex component -0.0348574
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0347726
VEZT vezatin, adherens junctions transmembrane protein -0.0344894
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0343312
SPATS2 spermatogenesis associated, serine-rich 2 -0.034202
ATXN2 ataxin 2 -0.0336299
STX8 syntaxin 8 -0.0334267
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0332745
BCL2L1 BCL2-like 1 -0.0329656
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.032887
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0327547
CYRIB CYFIP related Rac1 interactor B -0.0325914
BICD1 bicaudal D homolog 1 (Drosophila) -0.0325256
AKAP9 A kinase (PRKA) anchor protein 9 -0.0323182
FHIT fragile histidine triad -0.0321203
ELMO1 engulfment and cell motility 1 -0.0320078
PTPRJ protein tyrosine phosphatase, receptor type, J -0.031947
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0318702
EXOC6B exocyst complex component 6B -0.0316656
FAF2 Fas associated factor family member 2 -0.0313502
NEO1 neogenin 1 -0.031266
GSR glutathione reductase -0.0311247
PDIA3 protein disulfide isomerase family A, member 3 -0.0305221
TMCC1 transmembrane and coiled-coil domain family 1 -0.0304992
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0303297
SMIM44 small integral membrane protein 44 -0.0302537
TGFBI transforming growth factor, beta-induced, 68kDa -0.03018
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0301545
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -0.0295167
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0292814
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.029237
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0290694
GOLGA4 golgin A4 -0.0288096
KIFC3 kinesin family member C3 -0.0285956
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0283994
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.027793
EXOC4 exocyst complex component 4 -0.0277798
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.0276388
RBM47 RNA binding motif protein 47 -0.0275232
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0274213
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0272475
MTDH metadherin -0.0271981
PLEC plectin -0.0268851
ARL15 ADP-ribosylation factor-like 15 -0.026726
PRKCE protein kinase C, epsilon -0.0267063
BMPR1B bone morphogenetic protein receptor, type IB -0.0266048
PCED1B PC-esterase domain containing 1B -0.02658
PCNX2 pecanex 2 -0.0261781
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0261693
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.026153
IQCB1 IQ motif containing B1 -0.0261215
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0260704
TBL1X transducin (beta)-like 1X-linked -0.0260634
VMP1 vacuole membrane protein 1 -0.0260231
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0259229
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 -0.0258964
KPNB1 karyopherin (importin) beta 1 -0.0258446
IGF1R insulin-like growth factor 1 receptor -0.0258219
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0258095
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0258025
CDC42SE2 CDC42 small effector 2 -0.0256916
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0254835
ANTXR1 anthrax toxin receptor 1 -0.0254421
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.025414
PALLD palladin, cytoskeletal associated protein -0.0254004
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -0.0252364
R3HDM2 R3H domain containing 2 -0.0251904
OLA1 Obg-like ATPase 1 -0.0251511
ARHGAP24 Rho GTPase activating protein 24 -0.025143
COP1 COP1 E3 ubiquitin ligase -0.0250995
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 -0.0250984
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0249437
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0248699
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0248075
ZNRF3 zinc and ring finger 3 -0.0247941
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.0247577
ADAR adenosine deaminase, RNA-specific -0.0246286
TESC tescalcin -0.0245314
WNK1 WNK lysine deficient protein kinase 1 -0.0245246
ZNF704 zinc finger protein 704 -0.0242155
ALCAM activated leukocyte cell adhesion molecule -0.0241686
IL6ST interleukin 6 signal transducer -0.0241292
IKBIP IKBKB interacting protein -0.0241258
AHI1 Abelson helper integration site 1 -0.0241223
DENND4C DENN/MADD domain containing 4C -0.0240711
SOS1 son of sevenless homolog 1 (Drosophila) -0.0238515
TLN2 talin 2 -0.0236103
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0235793
VCAN versican -0.0235407
RC3H1 ring finger and CCCH-type domains 1 -0.0234838
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -0.0234826
AK1 adenylate kinase 1 -0.0234634
BLVRB biliverdin reductase B -0.0234106
TMEM245 transmembrane protein 245 -0.0234008
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0233182
SMAD3 SMAD family member 3 -0.0231873
SMC1A structural maintenance of chromosomes 1A -0.0231593
MARCHF7 membrane associated ring-CH-type finger 7 -0.0231509
PLD5 phospholipase D family, member 5 -0.0230806
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0230791
ANXA4 annexin A4 -0.0229673
DOCK5 dedicator of cytokinesis 5 -0.022953
NBEA neurobeachin -0.0229322
CLASRP CLK4-associating serine/arginine rich protein -0.0226251
NCOR1 nuclear receptor corepressor 1 -0.0226086
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0224556
R3HDM1 R3H domain containing 1 -0.0223865
CCND3 cyclin D3 -0.0223786
MAPK8 mitogen-activated protein kinase 8 -0.0223683
HIPK2 homeodomain interacting protein kinase 2 -0.0223333
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.022291
EDN1 endothelin 1 -0.0222601
IREB2 iron-responsive element binding protein 2 -0.0221114
TNPO3 transportin 3 -0.0220669
PIAS1 protein inhibitor of activated STAT, 1 -0.0219838
KIF13A kinesin family member 13A -0.0219
CDK6 cyclin-dependent kinase 6 -0.0218363
NUMB numb homolog (Drosophila) -0.0217599
OSBPL10 oxysterol binding protein-like 10 -0.0217547
SMIM14 small integral membrane protein 14 -0.0217476
NECTIN2 nectin cell adhesion molecule 2 -0.0217142
NLN neurolysin (metallopeptidase M3 family) -0.0216461
ASXL2 additional sex combs like transcriptional regulator 2 -0.0215831
KMT2A lysine (K)-specific methyltransferase 2A -0.0215395
FNDC3A fibronectin type III domain containing 3A -0.0215046
BIRC6 baculoviral IAP repeat containing 6 -0.0214832
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0214732
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.021464
PTPRF protein tyrosine phosphatase, receptor type, F -0.0214358
PPARG peroxisome proliferator-activated receptor gamma -0.0213868
ETF1 eukaryotic translation termination factor 1 -0.021375
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0213719
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -0.0212466
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0212264
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0212216
LDHB lactate dehydrogenase B -0.0211676
FAF1 Fas (TNFRSF6) associated factor 1 -0.0211066
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0209536
CCAR1 cell division cycle and apoptosis regulator 1 -0.0207342
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.0207067
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -0.020689
NMT1 N-myristoyltransferase 1 -0.0206794
RTTN rotatin -0.0205891
PTRH2 peptidyl-tRNA hydrolase 2 -0.020549
KIDINS220 kinase D-interacting substrate, 220kDa -0.0204299
RAB6A RAB6A, member RAS oncogene family -0.0204244
SSH2 slingshot protein phosphatase 2 -0.0204035
GOLM2 golgi membrane protein 2 -0.0204014
POLK polymerase (DNA directed) kappa -0.0203666
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0202559
TNRC18 trinucleotide repeat containing 18 -0.0202415
PER2 period circadian clock 2 -0.0201726
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0201429
TM4SF4 transmembrane 4 L six family member 4 -0.0201098
LMAN2 lectin, mannose-binding 2 -0.0201071
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0199208
SLC45A4 solute carrier family 45, member 4 -0.0199177
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.019884
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.0198089
COPA coatomer protein complex, subunit alpha -0.0197205
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0196666
UBAP2 ubiquitin associated protein 2 -0.0196351
WWTR1 WW domain containing transcription regulator 1 -0.0195713
ETV6 ets variant 6 -0.0195473
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -0.0195258
MSI2 musashi RNA-binding protein 2 -0.019499
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.019457
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -0.0194478
GPR39 G protein-coupled receptor 39 -0.0194337
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.0194079
CEP350 centrosomal protein 350kDa -0.0193912
ZFR zinc finger RNA binding protein -0.0193899
ITGA6 integrin, alpha 6 -0.0193576
BRCA1 breast cancer 1, early onset -0.019348
VCL vinculin -0.0193467
MPHOSPH9 M-phase phosphoprotein 9 -0.0193328
NCEH1 neutral cholesterol ester hydrolase 1 -0.0192698
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0192131
TTBK2 tau tubulin kinase 2 -0.019186
MYO9A myosin IXA -0.0191786
GPHN gephyrin -0.0191319
EIF5B eukaryotic translation initiation factor 5B -0.0191209
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0191036
TMEM65 transmembrane protein 65 -0.0190986
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -0.0190866
HNF1A HNF1 homeobox A -0.0190138
TTC7A tetratricopeptide repeat domain 7A -0.0189152
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0188232
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0187826
RARS1 arginyl-tRNA synthetase 1 -0.0187402
NSD1 nuclear receptor binding SET domain protein 1 -0.0186956
CNKSR3 CNKSR family member 3 -0.0186615
SFXN5 sideroflexin 5 -0.0186071
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0185817
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.0185686
KTN1 kinectin 1 (kinesin receptor) -0.0185607
SKIL SKI-like proto-oncogene -0.0184976
KAT6B K(lysine) acetyltransferase 6B -0.0184815
PRKCSH protein kinase C substrate 80K-H -0.0184677
MYLK myosin light chain kinase -0.0183995
CHKA choline kinase alpha -0.0183783
USP36 ubiquitin specific peptidase 36 -0.018357
P3H2 prolyl 3-hydroxylase 2 -0.018351
CCDC57 coiled-coil domain containing 57 -0.0183332
PANK2 pantothenate kinase 2 -0.0182782
CHD9 chromodomain helicase DNA binding protein 9 -0.0181426
CLCN7 chloride channel, voltage-sensitive 7 -0.0180881
KYNU kynureninase -0.0180672
PCNA proliferating cell nuclear antigen -0.018059
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0180354
UBXN7 UBX domain protein 7 -0.0180071
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0179655
PRICKLE2 prickle homolog 2 (Drosophila) -0.0179627
POTEF POTE ankyrin domain family, member F -0.0179611
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.017954
PDE7A phosphodiesterase 7A -0.0179157
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.0178952
FGG fibrinogen gamma chain -0.0178331
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0178265
LPP LIM domain containing preferred translocation partner in lipoma -0.0178117
BICC1 BicC family RNA binding protein 1 -0.0177927
EXT1 exostosin glycosyltransferase 1 -0.0177526
SMAD6 SMAD family member 6 -0.0177506
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0177442
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0176468
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -0.0176366
ZMYM4 zinc finger, MYM-type 4 -0.0176272
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0175284
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0174896
FMNL2 formin-like 2 -0.0174506
STAG2 stromal antigen 2 -0.0174272
PLCB4 phospholipase C, beta 4 -0.0174
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0173894
DSPP dentin sialophosphoprotein -0.0173892
JAG1 jagged 1 -0.0173872
MZT2A mitotic spindle organizing protein 2A -0.0173826
SCFD1 sec1 family domain containing 1 -0.0173352
RNF145 ring finger protein 145 -0.0173182
ZNF638 zinc finger protein 638 -0.0172553
RSRC1 arginine/serine-rich coiled-coil 1 -0.0172535
NCKAP1 NCK-associated protein 1 -0.0172111
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -0.0171906
PCDHB16 protocadherin beta 16 -0.0171698
COX5A cytochrome c oxidase subunit Va -0.0171518
PTPRK protein tyrosine phosphatase, receptor type, K -0.0170859
MED13 mediator complex subunit 13 -0.0169821
ADGRA3 adhesion G protein-coupled receptor A3 -0.0168931
SCAMP2 secretory carrier membrane protein 2 -0.0168836
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0168595
SRRM2 serine/arginine repetitive matrix 2 -0.0168566
IRS2 insulin receptor substrate 2 -0.016825
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa -0.0168247
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0167932
NEB nebulin -0.0167671
MEIS2 Meis homeobox 2 -0.0167026
SRPK2 SRSF protein kinase 2 -0.0166913
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.0166744
TRA2A transformer 2 alpha homolog (Drosophila) -0.0166388
SSR1 signal sequence receptor, alpha -0.0166175
DYM dymeclin -0.0166147
PRSS23 protease, serine, 23 -0.0165826
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.0165804
CENPP centromere protein P -0.0165733
SLC25A43 solute carrier family 25, member 43 -0.0165723
VAC14 Vac14 homolog (S. cerevisiae) -0.0165602
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0165174
USP3 ubiquitin specific peptidase 3 -0.0165146
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0164729
PBX1 pre-B-cell leukemia homeobox 1 -0.0164438
HDAC8 histone deacetylase 8 -0.0164312
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.0163381
ITSN2 intersectin 2 -0.0163372
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0163293
RAP1B RAP1B, member of RAS oncogene family -0.0163162
SLC37A3 solute carrier family 37, member 3 -0.0163144
BPTF bromodomain PHD finger transcription factor -0.0162979
PDE8A phosphodiesterase 8A -0.0162831
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0162766
BCAS3 breast carcinoma amplified sequence 3 -0.0162716
PKP4 plakophilin 4 -0.01627
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0162072
MIA3 melanoma inhibitory activity family, member 3 -0.0161743
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0161657
KIF20B kinesin family member 20B -0.0161236
PDE8B phosphodiesterase 8B -0.0161196
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0160566
TCF12 transcription factor 12 -0.0160553
BFAR bifunctional apoptosis regulator -0.0160116
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.015987
DCAF6 DDB1 and CUL4 associated factor 6 -0.015987
TMEM165 transmembrane protein 165 -0.0159807
APP amyloid beta (A4) precursor protein -0.0158676
BRD3 bromodomain containing 3 -0.0158136
PPP1R9A protein phosphatase 1, regulatory subunit 9A -0.0158126
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.0158105
RSBN1L round spermatid basic protein 1-like -0.0157498
PRRC2C proline-rich coiled-coil 2C -0.0157308
TCOF1 Treacher Collins-Franceschetti syndrome 1 -0.015698
RPS16 ribosomal protein S16 -0.0156746
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0156594
RPL27A ribosomal protein L27a -0.0156497
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.0156471
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0155784
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.0155721
KDM3B lysine (K)-specific demethylase 3B -0.0155638
ESRRA estrogen-related receptor alpha -0.0155386
CKAP5 cytoskeleton associated protein 5 -0.0154458
SQSTM1 sequestosome 1 -0.0154282
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -0.0154265
MGST1 microsomal glutathione S-transferase 1 -0.0154139
USP15 ubiquitin specific peptidase 15 -0.0153753
EVA1C eva-1 homolog C (C. elegans) -0.015363
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0152638
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.0152316
WEE1 WEE1 G2 checkpoint kinase -0.0151608
RNF13 ring finger protein 13 -0.0151127
COMMD1 copper metabolism (Murr1) domain containing 1 -0.0150582
FLNA filamin A, alpha -0.0150024
TSLIG1 tRNA splicing ligase complex subunit 1 -0.0149995
EVL Enah/Vasp-like -0.0149881
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0149709
GLB1 galactosidase, beta 1 -0.0149313
IL1R1 interleukin 1 receptor, type I -0.0149248
NOP58 NOP58 ribonucleoprotein -0.0149169
MPRIP myosin phosphatase Rho interacting protein -0.0149096
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0148971
FOXJ3 forkhead box J3 -0.0148955
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0148943
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0148866
MORC4 MORC family CW-type zinc finger 4 -0.0148407
FOXN2 forkhead box N2 -0.0148282
STK24 serine/threonine kinase 24 -0.0148253
RTN4RL2 reticulon 4 receptor-like 2 -0.014802
SNRPA small nuclear ribonucleoprotein polypeptide A -0.0148019
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0147942
RAB1A RAB1A, member RAS oncogene family -0.014778
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -0.0147775
DCDC2 doublecortin domain containing 2 -0.0147666
PLCH1 phospholipase C, eta 1 -0.0147658
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0147606
CCND1 cyclin D1 -0.0147263
MGLL monoglyceride lipase -0.0146979
TUBD1 tubulin, delta 1 -0.014682
ZNF518A zinc finger protein 518A -0.0146055
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0145929
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0145917
MGA MGA, MAX dimerization protein -0.0145863
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0145676
HELLS helicase, lymphoid-specific -0.0145518
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0145397
LMBR1 limb development membrane protein 1 -0.0145374
ZNF609 zinc finger protein 609 -0.0144926
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.014479
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0144754
SRRM1 serine/arginine repetitive matrix 1 -0.0144617
TET3 tet methylcytosine dioxygenase 3 -0.0144555
SLA2 Src-like-adaptor 2 -0.0144395
OTUD7B OTU deubiquitinase 7B -0.0144096
DICER1 dicer 1, ribonuclease type III -0.0143919
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.01439
STK38 serine/threonine kinase 38 -0.0143878
SRSF10 serine/arginine-rich splicing factor 10 -0.0143829
CIAO2A cytosolic iron-sulfur assembly component 2A -0.0143775
CREBBP CREB binding protein -0.0143662
SAFB2 scaffold attachment factor B2 -0.014363
WDFY3 WD repeat and FYVE domain containing 3 -0.0143629
NFX1 nuclear transcription factor, X-box binding 1 -0.0143595
WDR70 WD repeat domain 70 -0.0143386
CHEK2 checkpoint kinase 2 -0.0143354
KDM2A lysine (K)-specific demethylase 2A -0.0143249
DDB2 damage-specific DNA binding protein 2, 48kDa -0.0143208
WWC2 WW and C2 domain containing 2 -0.0143139
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.0142948
RMDN1 regulator of microtubule dynamics 1 -0.0142839
TGFBR3 transforming growth factor, beta receptor III -0.0142744
TPR translocated promoter region, nuclear basket protein -0.0142566
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.014253
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0142236
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) -0.0142119
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -0.0141969
RREB1 ras responsive element binding protein 1 -0.0141877
ARHGAP11A Rho GTPase activating protein 11A -0.0141767
SENP5 SUMO1/sentrin specific peptidase 5 -0.0141615
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0141441
RAB2A RAB2A, member RAS oncogene family -0.0141413
AQR aquarius intron-binding spliceosomal factor -0.0141346
ITGAV integrin, alpha V -0.0141346
AVPI1 arginine vasopressin-induced 1 -0.0141123
RNASE3 ribonuclease, RNase A family, 3 -0.0141026
MRTFA myocardin related transcription factor A -0.014087
ERBIN erbb2 interacting protein -0.0140828
ARHGAP11B Rho GTPase activating protein 11B -0.0140794
ARFGEF3 ARFGEF family member 3 -0.0140065
DESI2 desumoylating isopeptidase 2 -0.0139977
SETBP1 SET binding protein 1 -0.013979
PLXNB2 plexin B2 -0.0139655
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.013962
OXSR1 oxidative stress responsive 1 -0.0139589
PARD6B par-6 family cell polarity regulator beta -0.0139238
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0139086
MAP7 microtubule-associated protein 7 -0.0139029
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0139026
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0138984
IFT81 intraflagellar transport 81 -0.0138959
TMEM164 transmembrane protein 164 -0.0138656
TTLL6 tubulin tyrosine ligase-like family member 6 -0.0138621
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0138616
VRK3 vaccinia related kinase 3 -0.0138595
HELZ helicase with zinc finger -0.0138315
TRERF1 transcriptional regulating factor 1 -0.0138282
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.0138264
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0138254
PELP1 proline, glutamate and leucine rich protein 1 -0.0138234
NUP210 nucleoporin 210kDa -0.0138147
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.0138116
LAMB1 laminin, beta 1 -0.0138016
KDM4C lysine (K)-specific demethylase 4C -0.0137986
ASXL1 additional sex combs like transcriptional regulator 1 -0.0137508
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0137412
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0137244
QSER1 glutamine and serine rich 1 -0.013706
PHGDH phosphoglycerate dehydrogenase -0.0136898
SEC23IP SEC23 interacting protein -0.0136669
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) -0.0136562
TEX10 testis expressed 10 -0.0136379
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0136317
ESRRG estrogen-related receptor gamma -0.0136278
RFWD3 ring finger and WD repeat domain 3 -0.0136238
AOPEP aminopeptidase O (putative) -0.0135951
DIAPH2 diaphanous-related formin 2 -0.0135743
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0135515
METTL16 methyltransferase like 16 -0.0135262
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0135222
PTPRA protein tyrosine phosphatase, receptor type, A -0.0135049
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -0.0135031
TET1 tet methylcytosine dioxygenase 1 -0.0135014
GMDS GDP-mannose 4,6-dehydratase -0.0134982