A549_GSK J1_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 1µM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_GSK J1_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.156194
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.113621
KRT8 keratin 8, type II 0.109985
ENO1 enolase 1, (alpha) 0.0998226
RPLP1 ribosomal protein, large, P1 0.0934935
FLNA filamin A, alpha 0.0904861
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0857948
PKM pyruvate kinase, muscle 0.083561
KRT81 keratin 81, type II 0.0780862
MED13L mediator complex subunit 13-like 0.0738193
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0693682
UBL4A ubiquitin-like 4A 0.064517
GPX2 glutathione peroxidase 2 0.0636953
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0587208
AKR1C1 aldo-keto reductase family 1, member C1 0.0554749
MUSK muscle, skeletal, receptor tyrosine kinase 0.0531075
KRT18 keratin 18, type I 0.0526357
AGR2 anterior gradient 2 0.051883
FTL ferritin, light polypeptide 0.0492606
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0480795
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0479749
RPL8 ribosomal protein L8 0.0472106
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0462809
BSG basigin (Ok blood group) 0.0451922
SMYD3 SET and MYND domain containing 3 0.0450701
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0441164
ACTN4 actinin, alpha 4 0.0433219
PLEC plectin 0.0423818
RPL37A ribosomal protein L37a 0.0417988
EXT1 exostosin glycosyltransferase 1 0.041758
MAP7 microtubule-associated protein 7 0.0410703
SIK3 SIK family kinase 3 0.0408798
VCL vinculin 0.0405513
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.040016
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0398258
KYNU kynureninase 0.0393654
FADS2 fatty acid desaturase 2 0.0393497
AKR1C3 aldo-keto reductase family 1, member C3 0.0389861
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0387385
TUBB tubulin, beta class I 0.0377231
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0374962
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0372923
PCYOX1 prenylcysteine oxidase 1 0.0370301
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.037027
ZMYM4 zinc finger, MYM-type 4 0.036773
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.0354447
JUP junction plakoglobin 0.0354282
CLIP1 CAP-GLY domain containing linker protein 1 0.0349627
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0347439
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0347313
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0345882
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.034473
TPI1 triosephosphate isomerase 1 0.034454
SRPK2 SRSF protein kinase 2 0.0342702
ANXA1 annexin A1 0.0339376
RPL15 ribosomal protein L15 0.0336745
SRRM2 serine/arginine repetitive matrix 2 0.0334635
VCAN versican 0.0334509
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0324174
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0323554
MCMBP minichromosome maintenance complex binding protein 0.0323148
PHACTR4 phosphatase and actin regulator 4 0.0321995
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0319377
RBL1 retinoblastoma-like 1 0.0315009
PDZD8 PDZ domain containing 8 0.0314587
HMGA1 high mobility group AT-hook 1 0.0314191
WNT7B wingless-type MMTV integration site family, member 7B 0.0314062
ALCAM activated leukocyte cell adhesion molecule 0.0312536
CALR calreticulin 0.0311152
PDS5A PDS5 cohesin associated factor A 0.0309351
VIM vimentin 0.0304209
EEF2 eukaryotic translation elongation factor 2 0.03027
ACER3 alkaline ceramidase 3 0.0299858
AATF apoptosis antagonizing transcription factor 0.0299251
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 0.0299148
RPLP2 ribosomal protein, large, P2 0.0298862
RHOA ras homolog family member A 0.0295058
RPS5 ribosomal protein S5 0.0294256
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.0289673
TM4SF1 transmembrane 4 L six family member 1 0.028874
CANX calnexin 0.0288325
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0288231
RPS7 ribosomal protein S7 0.0287654
EIF4B eukaryotic translation initiation factor 4B 0.0287421
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0286915
CA12 carbonic anhydrase XII 0.0284648
FBXO17 F-box protein 17 0.0282664
HMGB1 high mobility group box 1 0.0282138
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0280491
PRRC2C proline-rich coiled-coil 2C 0.0279446
RNASEK ribonuclease, RNase K 0.0278662
INTS7 integrator complex subunit 7 0.0278323
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0275692
TMSB10 thymosin beta 10 0.027347
ATP5F1E ATP synthase F1 subunit epsilon 0.0272452
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0270013
GANAB glucosidase, alpha; neutral AB 0.0269516
ZCCHC7 zinc finger, CCHC domain containing 7 0.0269456
AKR1C2 aldo-keto reductase family 1, member C2 0.0268816
FTH1 ferritin, heavy polypeptide 1 0.0267809
PDIA6 protein disulfide isomerase family A, member 6 0.0266703
GDE1 glycerophosphodiester phosphodiesterase 1 0.0266379
IGSF11 immunoglobulin superfamily, member 11 0.0263225
TNS3 tensin 3 0.026242
PCDHB16 protocadherin beta 16 0.0261933
ZFHX3 zinc finger homeobox 3 0.0260264
TRAM1 translocation associated membrane protein 1 0.0259264
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0259081
RPS23 ribosomal protein S23 0.0258513
CD151 CD151 molecule (Raph blood group) 0.025676
CELF1 CUGBP, Elav-like family member 1 0.0256562
PTPRM protein tyrosine phosphatase, receptor type, M 0.0256481
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0256123
CLDN2 claudin 2 0.0255919
S100A10 S100 calcium binding protein A10 0.0254936
ZBTB38 zinc finger and BTB domain containing 38 0.0253589
ANXA2 annexin A2 0.0253004
RBBP6 retinoblastoma binding protein 6 0.0252755
MGLL monoglyceride lipase 0.025227
SCARB1 scavenger receptor class B, member 1 0.0250987
RPL23 ribosomal protein L23 0.0250939
RPS27A ribosomal protein S27a 0.0250245
CENPP centromere protein P 0.0249591
TMCC1 transmembrane and coiled-coil domain family 1 0.0248109
ACTG1 actin gamma 1 0.0246865
USP8 ubiquitin specific peptidase 8 0.0246726
NSRP1 nuclear speckle splicing regulatory protein 1 0.0244616
HACL2 2-hydroxyacyl-CoA lyase 2 0.0243044
PRRC2B proline-rich coiled-coil 2B 0.0242455
RHOT1 ras homolog family member T1 0.02424
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0241899
ACLY ATP citrate lyase 0.0241701
UBA2 ubiquitin-like modifier activating enzyme 2 0.0241483
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0241062
LMO7 LIM domain 7 0.0240741
RPS27 ribosomal protein S27 0.0240438
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.0240078
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 0.0239798
FNBP1L formin binding protein 1-like 0.0238703
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0237571
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0237527
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0237282
RUVBL1 RuvB-like AAA ATPase 1 0.0237143
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0236804
CALU calumenin 0.0236613
HOMER2 homer scaffolding protein 2 0.0236571
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.0236229
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.0235611
PLPP1 phospholipid phosphatase 1 0.0234895
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0232861
TUBA1B tubulin, alpha 1b 0.0232602
EPN1 epsin 1 0.0232397
CORO1C coronin, actin binding protein, 1C 0.0232033
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.0230983
ATF7IP activating transcription factor 7 interacting protein 0.0230484
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0230482
SLC35F5 solute carrier family 35, member F5 0.0229996
OSBPL10 oxysterol binding protein-like 10 0.0229057
TOP2B topoisomerase (DNA) II beta 180kDa 0.0227898
SECISBP2L SECIS binding protein 2-like 0.0227655
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0227309
CHD9 chromodomain helicase DNA binding protein 9 0.0226521
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0225422
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0225148
DAND5 DAN domain family member 5, BMP antagonist 0.0224569
POTEF POTE ankyrin domain family, member F 0.0223615
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0222906
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0222813
ESYT1 extended synaptotagmin-like protein 1 0.022173
IL6ST interleukin 6 signal transducer 0.0221553
PXDN peroxidasin 0.0220813
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.022075
MTF2 metal response element binding transcription factor 2 0.022069
EVA1C eva-1 homolog C (C. elegans) 0.0220163
AHCY adenosylhomocysteinase 0.0219886
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0217169
ABI2 abl-interactor 2 0.0216945
COPB1 coatomer protein complex, subunit beta 1 0.0213471
ITGB5 integrin, beta 5 0.0213469
IQGAP1 IQ motif containing GTPase activating protein 1 0.0213384
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0213198
CPNE1 copine I 0.0212503
NEK1 NIMA-related kinase 1 0.0210609
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0210184
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0210081
KIAA0232 KIAA0232 0.0209876
CCDC88A coiled-coil domain containing 88A 0.0209767
IPO7 importin 7 0.020921
EPAS1 endothelial PAS domain protein 1 0.0209139
FLNB filamin B, beta 0.0208817
DGKG diacylglycerol kinase, gamma 90kDa 0.0208574
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0207652
HDLBP high density lipoprotein binding protein 0.0206304
LMAN2 lectin, mannose-binding 2 0.0205828
FUS FUS RNA binding protein 0.0205228
MSH2 mutS homolog 2 0.0204847
APLP2 amyloid beta (A4) precursor-like protein 2 0.0204793
SEPTIN10 septin 10 0.020478
POM121C POM121 transmembrane nucleoporin C 0.020337
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0203334
RPS29 ribosomal protein S29 0.0203318
CAND1 cullin-associated and neddylation-dissociated 1 0.0202433
MFSD12 major facilitator superfamily domain containing 12 0.0201442
DHDDS dehydrodolichyl diphosphate synthase 0.0201428
PCNX4 pecanex 4 0.0201288
CD44 CD44 molecule (Indian blood group) 0.0201212
NRCAM neuronal cell adhesion molecule 0.0201026
ERGIC2 ERGIC and golgi 2 0.0200781
TLK1 tousled-like kinase 1 0.0200301
PFN1 profilin 1 0.0200213
NEK9 NIMA-related kinase 9 0.0199927
RPS2 ribosomal protein S2 0.0199421
MTUS1 microtubule associated tumor suppressor 1 0.0199158
RACK1 receptor for activated C kinase 1 0.0198978
CTSD cathepsin D 0.0198936
SDF4 stromal cell derived factor 4 0.0198668
TBCD tubulin folding cofactor D 0.0198355
HELLS helicase, lymphoid-specific 0.0197596
MMS22L MMS22-like, DNA repair protein 0.0197356
CTSA cathepsin A 0.0196445
WDR62 WD repeat domain 62 0.0196435
MRPS18B mitochondrial ribosomal protein S18B 0.0195915
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.0195579
SFTPA2 surfactant protein A2 0.0195523
UGDH UDP-glucose 6-dehydrogenase 0.0195248
KIAA1549 KIAA1549 0.0192885
TM4SF20 transmembrane 4 L six family member 20 0.019136
UIMC1 ubiquitin interaction motif containing 1 0.0190979
BZW2 basic leucine zipper and W2 domains 2 0.0190534
PLD5 phospholipase D family, member 5 0.0190377
SLC38A10 solute carrier family 38, member 10 0.0190025
SUMO2 small ubiquitin-like modifier 2 0.0189589
RBM15 RNA binding motif protein 15 0.0188816
MIA2 melanoma inhibitory activity 2 0.0188475
ATAD5 ATPase family, AAA domain containing 5 0.0188367
KMT2A lysine (K)-specific methyltransferase 2A 0.0187244
HM13 histocompatibility (minor) 13 0.018606
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0184198
PDGFD platelet derived growth factor D 0.0184056
KCTD1 potassium channel tetramerization domain containing 1 0.0183722
ATP5MC2 ATP synthase membrane subunit c locus 2 0.0183721
KIAA1671 KIAA1671 0.0183239
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0183042
HIP1 huntingtin interacting protein 1 0.0183038
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0182884
SH3RF1 SH3 domain containing ring finger 1 0.0182842
NUMB numb homolog (Drosophila) 0.0182211
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0182083
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0181967
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0181957
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.0181291
GFOD2 glucose-fructose oxidoreductase domain containing 2 0.018066
GLI2 GLI family zinc finger 2 0.0180621
GOLM1 golgi membrane protein 1 0.0180403
LPGAT1 lysophosphatidylglycerol acyltransferase 1 0.0179921
HERPUD2 HERPUD family member 2 0.0179797
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.0179648
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0179163
BBX bobby sox homolog (Drosophila) 0.0178486
SEC62 SEC62 homolog (S. cerevisiae) 0.0178338
RPL7 ribosomal protein L7 0.0177907
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.0177817
PHB2 prohibitin 2 0.0177649
ADNP activity-dependent neuroprotector homeobox 0.0177314
MTDH metadherin 0.0177177
DOCK9 dedicator of cytokinesis 9 0.0176277
TMEM184C transmembrane protein 184C 0.0176045
TBC1D5 TBC1 domain family, member 5 0.0175355
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.0174779
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.0174654
AHNAK2 AHNAK nucleoprotein 2 0.0173715
CEP128 centrosomal protein 128kDa 0.0173149
HSPH1 heat shock 105kDa/110kDa protein 1 0.0173008
GATAD2B GATA zinc finger domain containing 2B 0.0172862
LRP10 low density lipoprotein receptor-related protein 10 0.0172844
KLHL15 kelch-like family member 15 0.0172815
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0172795
HAT1 histone acetyltransferase 1 0.0172462
GSTP1 glutathione S-transferase pi 1 0.0172458
ZFAND3 zinc finger, AN1-type domain 3 0.0172437
RPS9 ribosomal protein S9 0.0172338
GPS2 G protein pathway suppressor 2 0.0172233
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.0172145
COL4A2 collagen, type IV, alpha 2 0.0171809
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0171574
SEC11A SEC11 homolog A (S. cerevisiae) 0.0171192
TCP11L1 t-complex 11, testis-specific-like 1 0.0171151
NKRF NFKB repressing factor 0.0170883
MANF mesencephalic astrocyte-derived neurotrophic factor 0.0169908
PUM3 pumilio RNA binding family member 3 0.0169685
TMTC3 transmembrane and tetratricopeptide repeat containing 3 0.0169515
TSPAN4 tetraspanin 4 0.0168976
ATXN2L ataxin 2-like 0.0168956
IGFBP3 insulin-like growth factor binding protein 3 0.0168855
CLEC16A C-type lectin domain family 16, member A 0.0168853
NUCB1 nucleobindin 1 0.0168419
ADAR adenosine deaminase, RNA-specific 0.0168257
TPM2 tropomyosin 2 (beta) 0.0167987
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0167841
TRIM28 tripartite motif containing 28 0.0167598
EVL Enah/Vasp-like 0.0167435
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0167164
MGST3 microsomal glutathione S-transferase 3 0.0167101
EXOC6 exocyst complex component 6 0.0166744
CREBBP CREB binding protein 0.0166437
RNPS1 RNA binding protein S1, serine-rich domain 0.0166371
UBOX5 U-box domain containing 5 0.0166294
CCNK cyclin K 0.016622
NSFL1C NSFL1 (p97) cofactor (p47) 0.0166002
CD63 CD63 molecule 0.0165226
TAGLN2 transgelin 2 0.0164714
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0164113
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0164087
RFX7 regulatory factor X, 7 0.016349
LPAR1 lysophosphatidic acid receptor 1 0.016327
ZMIZ1 zinc finger, MIZ-type containing 1 0.0162558
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.0162457
HDAC1 histone deacetylase 1 0.0162229
ITGB4 integrin, beta 4 0.0162044
WARS1 tryptophanyl-tRNA synthetase 1 0.016191
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.0161818
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0161652
RPL7A ribosomal protein L7a 0.0161454
DDRGK1 DDRGK domain containing 1 0.0161326
PIR pirin (iron-binding nuclear protein) 0.0161064
ANTXR1 anthrax toxin receptor 1 0.016093
PGRMC1 progesterone receptor membrane component 1 0.0160799
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0160732
XPO1 exportin 1 0.0160633
DIAPH1 diaphanous-related formin 1 0.0159746
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 0.015934
CENPE centromere protein E, 312kDa 0.0159321
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0158742
PDCD11 programmed cell death 11 0.0158537
MBD4 methyl-CpG binding domain protein 4 0.0158529
PITRM1 pitrilysin metallopeptidase 1 0.0158392
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0158013
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0157904
AHI1 Abelson helper integration site 1 0.0157871
CADM1 cell adhesion molecule 1 0.0157653
LAPTM4B lysosomal protein transmembrane 4 beta 0.0157615
S100A6 S100 calcium binding protein A6 0.0157487
SYNGR2 synaptogyrin 2 0.0157229
CHD6 chromodomain helicase DNA binding protein 6 0.0157203
RECQL RecQ helicase-like 0.0157025
KIAA0753 KIAA0753 0.015682
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0156365
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0156006
REST RE1-silencing transcription factor 0.0155884
TCAIM T cell activation inhibitor, mitochondrial 0.0155706
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.0155554
ELOB elongin B 0.0154934
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0154783
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0154184
JAK1 Janus kinase 1 0.0154073
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.0153818
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.0153017
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.0152807
SASH1 SAM and SH3 domain containing 1 0.0152285
NFE2L2 nuclear factor, erythroid 2-like 2 0.0152038
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.0152002
EPN2 epsin 2 0.015183
AUTS2 autism susceptibility candidate 2 0.0151512
KIFC3 kinesin family member C3 0.0151437
LPIN2 lipin 2 0.0151164
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0150443
LMNB1 lamin B1 0.0150143
TET1 tet methylcytosine dioxygenase 1 0.0149937
TNS4 tensin 4 0.0149725
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.014967
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.0149619
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.0149516
NHSL3 NHS like 3 0.0149369
HIPK2 homeodomain interacting protein kinase 2 0.0149366
PLCE1 phospholipase C, epsilon 1 0.0149256
CUX1 cut-like homeobox 1 0.0149135
EXO1 exonuclease 1 0.0148374
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 0.0148369
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.0148364
LARS1 leucyl-tRNA synthetase 1 0.0148275
ZDHHC3 zinc finger, DHHC-type containing 3 0.0148146
SCFD2 sec1 family domain containing 2 0.0147872
HCFC1 host cell factor C1 0.0147778
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.0147475
FAM120C family with sequence similarity 120C 0.0147429
FANCL Fanconi anemia, complementation group L 0.0146698
C19ORF53 chromosome 19 open reading frame 53 0.0146516
CSDE1 cold shock domain containing E1, RNA-binding 0.0146249
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0145979
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.0145811
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.0145805
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0145698
CBR1 carbonyl reductase 1 0.0145136
LAMP1 lysosomal-associated membrane protein 1 0.0145092
ZNF451 zinc finger protein 451 0.0144853
FBXL5 F-box and leucine-rich repeat protein 5 0.0144619
SEC63 SEC63 homolog (S. cerevisiae) 0.0144546
SYPL1 synaptophysin-like 1 0.0144188
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0144059
NIN ninein (GSK3B interacting protein) 0.014371
CNN2 calponin 2 0.0143419
ZNF518A zinc finger protein 518A 0.0143079
RNF111 ring finger protein 111 0.0142962
RAB15 RAB15, member RAS oncogene family 0.0142882
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0.0142601
TTC39C tetratricopeptide repeat domain 39C 0.0142246
COBL cordon-bleu WH2 repeat protein 0.0141877
RAP1B RAP1B, member of RAS oncogene family 0.0141825
LMAN2L lectin, mannose-binding 2-like 0.01417
R3HDM2 R3H domain containing 2 0.0141682
RNF217 ring finger protein 217 0.0141272
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0141166
SAMD5 sterile alpha motif domain containing 5 0.0141108
LAPTM4A lysosomal protein transmembrane 4 alpha 0.014066
HINT1 histidine triad nucleotide binding protein 1 0.0140555
ZFAND5 zinc finger, AN1-type domain 5 0.0139998
DPYD dihydropyrimidine dehydrogenase 0.0139819
GLRX3 glutaredoxin 3 0.0139777
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.0139507
INSR insulin receptor 0.0139134
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 0.0139047
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.01387
RRM2 ribonucleotide reductase M2 0.0138449
DYNC2I2 dynein 2 intermediate chain 2 0.0138449
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.0138236
DNPEP aspartyl aminopeptidase 0.0138215
ECHDC1 ethylmalonyl-CoA decarboxylase 1 0.0138069
DOK4 docking protein 4 0.0138045
PRELID2 PRELI domain containing 2 0.0138011
RPL39 ribosomal protein L39 0.0137926
TMEM92 transmembrane protein 92 0.0137718
FASN fatty acid synthase 0.0137591
LBR lamin B receptor 0.0137511
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0137462
NEK3 NIMA-related kinase 3 0.0137107
SPC25 SPC25, NDC80 kinetochore complex component 0.0136626
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.013653
ENOX2 ecto-NOX disulfide-thiol exchanger 2 0.0136527
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0136506
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.0136227
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.0136118
YBX3 Y box binding protein 3 0.0136095
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0136069
PHGDH phosphoglycerate dehydrogenase 0.0135479
NSD1 nuclear receptor binding SET domain protein 1 0.0135427
CTPS2 CTP synthase 2 0.0135357
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0135309
ACO2 aconitase 2, mitochondrial 0.013512
NAXE NAD(P)HX epimerase 0.0135028
GLMN glomulin, FKBP associated protein 0.0134943
STYXL1 serine/threonine/tyrosine interacting-like 1 0.01348
TSC22D1 TSC22 domain family, member 1 0.0134671
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.0134604
FERMT2 fermitin family member 2 0.0134426
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0134135
NOP56 NOP56 ribonucleoprotein 0.0134114
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 0.0134088
FBL fibrillarin 0.0133978
CPNE4 copine IV 0.0133868
GSPT1 G1 to S phase transition 1 0.0133796
SETBP1 SET binding protein 1 0.0133741
COX5B cytochrome c oxidase subunit Vb 0.013371
SH3BP4 SH3-domain binding protein 4 0.0133098
RPS14 ribosomal protein S14 0.0132759
PIGX phosphatidylinositol glycan anchor biosynthesis, class X 0.0132714
RPL12 ribosomal protein L12 0.0132673
CDK10 cyclin-dependent kinase 10 0.0132653
HBS1L HBS1-like translational GTPase 0.0132651
CYBA cytochrome b-245, alpha polypeptide 0.0132604
DMXL2 Dmx-like 2 0.0132577
ANLN anillin, actin binding protein 0.0132554
RPL27A ribosomal protein L27a 0.0132254
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.0132202
PROCR protein C receptor, endothelial 0.0132134
SON SON DNA binding protein 0.0132065
NCOA3 nuclear receptor coactivator 3 0.0131833
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 0.013181
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.0131649
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0131625
ZNF37A zinc finger protein 37A 0.0131429
PDLIM5 PDZ and LIM domain 5 0.0131428
MIMS1 mitochondrial inner membrane scaffold 1 0.0131396
LDHA lactate dehydrogenase A 0.013122
SUCLG1 succinate-CoA ligase, alpha subunit 0.0131214
CPA6 carboxypeptidase A6 0.0131211
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.0131045
RPL26 ribosomal protein L26 0.0131027
SKAP2 src kinase associated phosphoprotein 2 0.0130904
KRT19 keratin 19, type I 0.0130887
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0130758
SCAF1 SR-related CTD-associated factor 1 0.0130564
IVD isovaleryl-CoA dehydrogenase 0.0130453
ERGIC3 ERGIC and golgi 3 0.0130269
TM9SF2 transmembrane 9 superfamily member 2 0.0130239
SLC35F6 solute carrier family 35, member F6 0.0130219
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.0130196
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0130052
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0129572
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 0.0129329
TMEM267 transmembrane protein 267 0.0129232

decreased expression

Symbol Name Standardized Value
TXNRD1 thioredoxin reductase 1 -0.142744
ZBTB20 zinc finger and BTB domain containing 20 -0.13567
PDE4D phosphodiesterase 4D, cAMP-specific -0.135436
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.101715
PTGR1 prostaglandin reductase 1 -0.082589
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -0.0772595
MCU mitochondrial calcium uniporter -0.0676972
AOPEP aminopeptidase O (putative) -0.0672599
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.067143
EXOC6B exocyst complex component 6B -0.0597366
TTC28 tetratricopeptide repeat domain 28 -0.0562526
MGST1 microsomal glutathione S-transferase 1 -0.0551636
THSD4 thrombospondin, type I, domain containing 4 -0.0548694
GPC6 glypican 6 -0.0531354
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -0.0523327
SYT1 synaptotagmin I -0.0523228
NCOR1 nuclear receptor corepressor 1 -0.0521121
EHBP1 EH domain binding protein 1 -0.0516017
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0512603
JMJD1C jumonji domain containing 1C -0.0497537
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0497198
DOCK5 dedicator of cytokinesis 5 -0.0496768
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0495827
NF1 neurofibromin 1 -0.0486243
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0484675
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0480857
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0480406
WWTR1 WW domain containing transcription regulator 1 -0.047533
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0471243
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0467886
RBM6 RNA binding motif protein 6 -0.0464162
USP9X ubiquitin specific peptidase 9, X-linked -0.0461733
PRKCA protein kinase C, alpha -0.0459543
CAMK2D calcium/calmodulin-dependent protein kinase II delta -0.0425758
ARHGAP26 Rho GTPase activating protein 26 -0.0420774
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.041362
PDE10A phosphodiesterase 10A -0.0407676
VMP1 vacuole membrane protein 1 -0.0406074
WWOX WW domain containing oxidoreductase -0.0398264
FMNL2 formin-like 2 -0.0395937
ANKRD17 ankyrin repeat domain 17 -0.0395524
AHCYL2 adenosylhomocysteinase-like 2 -0.0393807
ASPH aspartate beta-hydroxylase -0.038934
GLIS3 GLIS family zinc finger 3 -0.0384325
RAB1A RAB1A, member RAS oncogene family -0.0383144
NTN4 netrin 4 -0.0381359
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0379771
SLC35F3 solute carrier family 35, member F3 -0.0376003
GCLC glutamate-cysteine ligase, catalytic subunit -0.0372038
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0365646
GPATCH8 G patch domain containing 8 -0.0362089
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0361082
CNTN1 contactin 1 -0.0359146
FAF1 Fas (TNFRSF6) associated factor 1 -0.0359122
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.035513
R3HDM1 R3H domain containing 1 -0.0354442
MLPH melanophilin -0.0354287
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0353395
AGO2 argonaute RISC catalytic component 2 -0.0351987
OPHN1 oligophrenin 1 -0.0350608
RPS11 ribosomal protein S11 -0.0346729
RNF216 ring finger protein 216 -0.0345208
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -0.0342275
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0341699
PTPRJ protein tyrosine phosphatase, receptor type, J -0.0341235
FOXP1 forkhead box P1 -0.03398
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0336798
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0335207
TUBD1 tubulin, delta 1 -0.0330368
DAPK1 death-associated protein kinase 1 -0.0327694
CNTNAP3B contactin associated protein-like 3B -0.0326724
FNDC3B fibronectin type III domain containing 3B -0.0326334
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0325089
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0322146
ANKRD11 ankyrin repeat domain 11 -0.0321315
UBE2K ubiquitin-conjugating enzyme E2K -0.032019
SKIL SKI-like proto-oncogene -0.0318066
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0316227
SQSTM1 sequestosome 1 -0.0315773
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0314895
BICC1 BicC family RNA binding protein 1 -0.0314762
TBC1D22A TBC1 domain family, member 22A -0.0314718
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -0.0313538
SPIDR scaffolding protein involved in DNA repair -0.0312664
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0311135
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0310065
RBM47 RNA binding motif protein 47 -0.0303394
CDC27 cell division cycle 27 -0.0302274
RAB10 RAB10, member RAS oncogene family -0.0300772
KMT2E lysine (K)-specific methyltransferase 2E -0.0300288
TNPO1 transportin 1 -0.029959
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.029847
RBM23 RNA binding motif protein 23 -0.0296863
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0296423
MIS18BP1 MIS18 binding protein 1 -0.0295934
FHIT fragile histidine triad -0.0293755
BMPR1B bone morphogenetic protein receptor, type IB -0.0292325
PTGES2 prostaglandin E synthase 2 -0.0291661
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0289608
MRTFA myocardin related transcription factor A -0.0289492
CCDC57 coiled-coil domain containing 57 -0.0289412
SMAD3 SMAD family member 3 -0.0288837
OLA1 Obg-like ATPase 1 -0.0288329
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0287977
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -0.0283475
SVIL supervillin -0.0282829
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0282758
DENND4C DENN/MADD domain containing 4C -0.0282098
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0279644
LUC7L LUC7-like (S. cerevisiae) -0.0279054
ARHGAP5 Rho GTPase activating protein 5 -0.027896
MYADM myeloid-associated differentiation marker -0.0278871
COL5A2 collagen, type V, alpha 2 -0.0278698
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.0274911
RNF145 ring finger protein 145 -0.0274054
SPAG9 sperm associated antigen 9 -0.0273507
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.027295
SETD5 SET domain containing 5 -0.0272737
CLIP2 CAP-GLY domain containing linker protein 2 -0.0272712
THOC2 THO complex 2 -0.0272049
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0271645
VEZT vezatin, adherens junctions transmembrane protein -0.0271537
IRS2 insulin receptor substrate 2 -0.0271439
ZFP64 ZFP64 zinc finger protein -0.0269188
TTC17 tetratricopeptide repeat domain 17 -0.0268808
AKAP12 A kinase (PRKA) anchor protein 12 -0.0268801
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0267694
TNRC6B trinucleotide repeat containing 6B -0.0267595
POGZ pogo transposable element with ZNF domain -0.0267384
NPEPPS aminopeptidase puromycin sensitive -0.0264905
RHEB Ras homolog enriched in brain -0.0264678
FN1 fibronectin 1 -0.0264232
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0264134
GTF2IRD1 GTF2I repeat domain containing 1 -0.0263891
UBE2H ubiquitin-conjugating enzyme E2H -0.0263442
PDE8A phosphodiesterase 8A -0.0262813
RSF1 remodeling and spacing factor 1 -0.0262334
LRMDA leucine rich melanocyte differentiation associated -0.0260548
RIOK3 RIO kinase 3 -0.0259209
SYNJ2 synaptojanin 2 -0.0255195
SPATS2 spermatogenesis associated, serine-rich 2 -0.025481
FOXJ3 forkhead box J3 -0.0254109
DENND4A DENN/MADD domain containing 4A -0.0253861
OGA O-GlcNAcase -0.0253158
CP ceruloplasmin (ferroxidase) -0.0252077
ATAD2B ATPase family, AAA domain containing 2B -0.025145
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0250655
KDM2A lysine (K)-specific demethylase 2A -0.0250564
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0250337
IST1 increased sodium tolerance 1 homolog (yeast) -0.0249767
NHSL1 NHS-like 1 -0.0247397
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0246801
RANBP17 RAN binding protein 17 -0.0246031
DSCAM Down syndrome cell adhesion molecule -0.0246015
SEPTIN6 septin 6 -0.0245984
BCAS3 breast carcinoma amplified sequence 3 -0.0244402
BCL2L1 BCL2-like 1 -0.0243789
FBXL20 F-box and leucine-rich repeat protein 20 -0.0242312
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.0240874
CAMKMT calmodulin-lysine N-methyltransferase -0.0240869
RNF38 ring finger protein 38 -0.0237942
PER2 period circadian clock 2 -0.0237506
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0236532
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0234525
PPP1R21 protein phosphatase 1, regulatory subunit 21 -0.0234447
YAP1 Yes-associated protein 1 -0.0233725
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.0233014
KDM3B lysine (K)-specific demethylase 3B -0.0232717
SCN8A sodium channel, voltage gated, type VIII alpha subunit -0.0232146
DNMBP dynamin binding protein -0.023115
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0230537
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 -0.0230292
PTEN phosphatase and tensin homolog -0.0230213
FOSL1 FOS-like antigen 1 -0.0230206
MTA3 metastasis associated 1 family, member 3 -0.0229277
USP3 ubiquitin specific peptidase 3 -0.0229161
PARD3 par-3 family cell polarity regulator -0.022857
DTNB dystrobrevin, beta -0.0226698
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0226588
DIAPH2 diaphanous-related formin 2 -0.022655
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0224926
CCDC91 coiled-coil domain containing 91 -0.0224625
ZNF292 zinc finger protein 292 -0.0224424
PUM2 pumilio RNA-binding family member 2 -0.0222749
TNRC6A trinucleotide repeat containing 6A -0.0220401
FAM177A1 family with sequence similarity 177, member A1 -0.0219152
UNC13B unc-13 homolog B (C. elegans) -0.0219104
RUFY2 RUN and FYVE domain containing 2 -0.0217925
KRT7 keratin 7, type II -0.0217753
PRKD2 protein kinase D2 -0.0217114
PLEKHA6 pleckstrin homology domain containing, family A member 6 -0.0216747
MYO18A myosin XVIIIA -0.0214995
VPS35L VPS35 endosomal protein sorting factor like -0.0214813
SOS1 son of sevenless homolog 1 (Drosophila) -0.021414
RPN2 ribophorin II -0.0213804
RABGAP1L RAB GTPase activating protein 1-like -0.0213713
MPHOSPH9 M-phase phosphoprotein 9 -0.0212053
ST7L suppression of tumorigenicity 7 like -0.020987
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0208915
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.0208427
DENND1A DENN/MADD domain containing 1A -0.0208234
GCC2 GRIP and coiled-coil domain containing 2 -0.0208209
PARD3B par-3 family cell polarity regulator beta -0.0207418
ARL15 ADP-ribosylation factor-like 15 -0.0207326
TGIF1 TGFB-induced factor homeobox 1 -0.0207065
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0206785
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.020668
PRKCE protein kinase C, epsilon -0.0206442
WDPCP WD repeat containing planar cell polarity effector -0.0206379
DLG5 discs, large homolog 5 (Drosophila) -0.0205978
TMEM87A transmembrane protein 87A -0.0205697
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0205352
NIPSNAP2 nipsnap homolog 2 -0.02052
BRD4 bromodomain containing 4 -0.0204498
SLC39A11 solute carrier family 39, member 11 -0.0203972
AREG amphiregulin -0.0203231
ANKRD44 ankyrin repeat domain 44 -0.0203038
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0202572
TBK1 TANK-binding kinase 1 -0.0201882
LRRK1 leucine-rich repeat kinase 1 -0.020184
MAML3 mastermind-like 3 (Drosophila) -0.0201795
PLD3 phospholipase D family, member 3 -0.0201665
RBM20 RNA binding motif protein 20 -0.0200949
SMAD2 SMAD family member 2 -0.0200784
RPS8 ribosomal protein S8 -0.020069
TRA2A transformer 2 alpha homolog (Drosophila) -0.0200655
FBXO11 F-box protein 11 -0.0200623
CDK19 cyclin-dependent kinase 19 -0.0200164
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0199799
ANAPC5 anaphase promoting complex subunit 5 -0.0199727
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0199015
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.0198779
PRDX1 peroxiredoxin 1 -0.0198533
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0197887
ANXA4 annexin A4 -0.0197306
RAB5A RAB5A, member RAS oncogene family -0.0195967
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.0194719
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0194065
PCDH9 protocadherin 9 -0.0193876
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0193556
HDGFL3 HDGF like 3 -0.0193522
SREBF2 sterol regulatory element binding transcription factor 2 -0.0193327
LTBP1 latent transforming growth factor beta binding protein 1 -0.019233
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0192256
PRPF6 pre-mRNA processing factor 6 -0.019223
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -0.0191964
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0191395
LPIN1 lipin 1 -0.0191078
RAB6A RAB6A, member RAS oncogene family -0.0190132
DST dystonin -0.019
NKTR natural killer cell triggering receptor -0.0189982
AP1S3 adaptor-related protein complex 1, sigma 3 subunit -0.0189659
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.0189511
RHBDD1 rhomboid domain containing 1 -0.0189168
ZNF652 zinc finger protein 652 -0.0189164
FAM20B family with sequence similarity 20, member B -0.0188984
DENND6A DENN/MADD domain containing 6A -0.0188971
RASA2 RAS p21 protein activator 2 -0.0188884
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0188816
SINHCAF SIN3-HDAC complex associated factor -0.0188607
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -0.0188506
SH3D19 SH3 domain containing 19 -0.0188227
METAP2 methionyl aminopeptidase 2 -0.0187439
H4C3 H4 clustered histone 3 -0.0187254
CKAP5 cytoskeleton associated protein 5 -0.0186931
USP15 ubiquitin specific peptidase 15 -0.0186877
RPL37 ribosomal protein L37 -0.0186825
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -0.0185884
FBXW4 F-box and WD repeat domain containing 4 -0.0185738
CEP350 centrosomal protein 350kDa -0.0185728
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.0185698
TMED8 transmembrane emp24 protein transport domain containing 8 -0.018533
FNBP4 formin binding protein 4 -0.0184082
RPH3AL rabphilin 3A-like (without C2 domains) -0.018406
HEATR1 HEAT repeat containing 1 -0.0183422
LIMD1 LIM domains containing 1 -0.0182535
MSI2 musashi RNA-binding protein 2 -0.0182141
THSD7A thrombospondin, type I, domain containing 7A -0.0181948
DCLRE1C DNA cross-link repair 1C -0.0181752
ETF1 eukaryotic translation termination factor 1 -0.0181698
SOS2 son of sevenless homolog 2 (Drosophila) -0.0181638
RSPRY1 ring finger and SPRY domain containing 1 -0.0181583
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.0181451
MDFIC MyoD family inhibitor domain containing -0.0181213
PCBP2 poly(rC) binding protein 2 -0.0181038
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -0.0180903
SLC38A1 solute carrier family 38, member 1 -0.0180441
DEAF1 DEAF1 transcription factor -0.0180226
ACOD1 aconitate decarboxylase 1 -0.0179832
GMDS GDP-mannose 4,6-dehydratase -0.0178728
SP3 Sp3 transcription factor -0.017866
PLS1 plastin 1 -0.0178322
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -0.0178135
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0178121
BRD3 bromodomain containing 3 -0.0177757
SEC31A SEC31 homolog A (S. cerevisiae) -0.0177702
PEAK1 pseudopodium-enriched atypical kinase 1 -0.0177489
WDR43 WD repeat domain 43 -0.0177376
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -0.0177065
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.017699
WWC1 WW and C2 domain containing 1 -0.0176384
UBP1 upstream binding protein 1 (LBP-1a) -0.017586
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.017583
RAI1 retinoic acid induced 1 -0.0175543
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0175112
USP47 ubiquitin specific peptidase 47 -0.0174817
ATE1 arginyltransferase 1 -0.0174817
ARHGAP24 Rho GTPase activating protein 24 -0.0174235
AKAP8 A kinase (PRKA) anchor protein 8 -0.0174202
GCN1 GCN1 activator of EIF2AK4 -0.0173972
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0173949
UBN2 ubinuclein 2 -0.0173668
VASP vasodilator-stimulated phosphoprotein -0.0173484
MTFMT mitochondrial methionyl-tRNA formyltransferase -0.0173393
PDE7A phosphodiesterase 7A -0.0173299
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0173208
CLASP1 cytoplasmic linker associated protein 1 -0.0172204
DCAF10 DDB1 and CUL4 associated factor 10 -0.0171982
PGK1 phosphoglycerate kinase 1 -0.01713
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -0.0170594
BCL2L13 BCL2-like 13 (apoptosis facilitator) -0.0170566
PRPF8 pre-mRNA processing factor 8 -0.0170559
USO1 USO1 vesicle transport factor -0.0170514
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0170459
RPS12 ribosomal protein S12 -0.0169897
SPAG1 sperm associated antigen 1 -0.0169776
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0169248
ATXN7L1 ataxin 7-like 1 -0.0168185
PICALM phosphatidylinositol binding clathrin assembly protein -0.0167876
SLC38A9 solute carrier family 38, member 9 -0.0167112
MTMR3 myotubularin related protein 3 -0.0166949
UTRN utrophin -0.0166849
IPO9 importin 9 -0.0166568
PANK2 pantothenate kinase 2 -0.016572
TBC1D15 TBC1 domain family, member 15 -0.0165707
PLA2R1 phospholipase A2 receptor 1, 180kDa -0.0165606
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.0165482
RLF rearranged L-myc fusion -0.0165401
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0165393
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0165106
PHF21A PHD finger protein 21A -0.0164614
MACO1 macoilin 1 -0.0164558
KIF4A kinesin family member 4A -0.0164358
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.0163881
IWS1 IWS1 homolog (S. cerevisiae) -0.0163313
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0162757
GABPB1 GA binding protein transcription factor, beta subunit 1 -0.0162098
DIS3L DIS3 like exosome 3'-5' exoribonuclease -0.0162027
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0161936
CENPB centromere protein B, 80kDa -0.0160921
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.0160468
EFNA5 ephrin-A5 -0.0160451
RC3H2 ring finger and CCCH-type domains 2 -0.0160423
TMOD3 tropomodulin 3 (ubiquitous) -0.0160252
CLIP4 CAP-GLY domain containing linker protein family, member 4 -0.0160227
ENAH enabled homolog (Drosophila) -0.0160016
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0159954
KHSRP KH-type splicing regulatory protein -0.0159834
NSD3 nuclear receptor binding SET domain protein 3 -0.0159576
KIAA0319 KIAA0319 -0.0159367
PDCD6IP programmed cell death 6 interacting protein -0.0159215
CBX1 chromobox homolog 1 -0.0159183
NNMT nicotinamide N-methyltransferase -0.0158982
MFF mitochondrial fission factor -0.0158904
E2F6 E2F transcription factor 6 -0.0158318
RSL24D1 ribosomal L24 domain containing 1 -0.0158122
WTAP Wilms tumor 1 associated protein -0.0158098
KCMF1 potassium channel modulatory factor 1 -0.0157827
PTMS parathymosin -0.0157336
C1RL complement component 1, r subcomponent-like -0.0157189
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0157188
STIM1 stromal interaction molecule 1 -0.0156562
LCOR ligand dependent nuclear receptor corepressor -0.0156265
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.0156079
WDR82 WD repeat domain 82 -0.0155865
HILPDA hypoxia inducible lipid droplet-associated -0.0155746
ABI1 abl-interactor 1 -0.0155438
MYOF myoferlin -0.0155374
ACTN1 actinin, alpha 1 -0.0155324
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0155049
CEP89 centrosomal protein 89kDa -0.0154956
EIF4A1 eukaryotic translation initiation factor 4A1 -0.01549
DIPK1A divergent protein kinase domain 1A -0.0154897
MYO19 myosin XIX -0.0154867
STX1A syntaxin 1A (brain) -0.0154414
KDM4B lysine (K)-specific demethylase 4B -0.0154304
JARID2 jumonji, AT rich interactive domain 2 -0.0154163
ERP44 endoplasmic reticulum protein 44 -0.0153949
ZFAND6 zinc finger, AN1-type domain 6 -0.015391
GNB5 guanine nucleotide binding protein (G protein), beta 5 -0.0153723
DYM dymeclin -0.0153634
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 -0.0153494
ZNF280D zinc finger protein 280D -0.0153396
MRPS27 mitochondrial ribosomal protein S27 -0.0153224
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0152667
CDC73 cell division cycle 73 -0.015257
GRIPAP1 GRIP1 associated protein 1 -0.0152502
TMEM131 transmembrane protein 131 -0.0152499
WNK1 WNK lysine deficient protein kinase 1 -0.01524
SERBP1 SERPINE1 mRNA binding protein 1 -0.0152087
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0151979
MYO1D myosin ID -0.0151853
NSD2 nuclear receptor binding SET domain protein 2 -0.0151753
SAMD4B sterile alpha motif domain containing 4B -0.0151568
ZNF638 zinc finger protein 638 -0.0151484
FGF13 fibroblast growth factor 13 -0.015145
NBAS neuroblastoma amplified sequence -0.015117
EPB41 erythrocyte membrane protein band 4.1 -0.0151131
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 -0.0150759
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0150551
CPNE8 copine VIII -0.0150406
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0150276
ZNF124 zinc finger protein 124 -0.0150212
AURKB aurora kinase B -0.0149985
CADM2 cell adhesion molecule 2 -0.0149705
SPPL3 signal peptide peptidase like 3 -0.0149677
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0149403
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.014934
DYNC2I1 dynein 2 intermediate chain 1 -0.0149278
EGR1 early growth response 1 -0.0149249
UBXN7 UBX domain protein 7 -0.0149023
NCKAP1 NCK-associated protein 1 -0.0148913
DUSP4 dual specificity phosphatase 4 -0.0148621
SHLD2 shieldin complex subunit 2 -0.0148557
KIF3C kinesin family member 3C -0.0148275
GRB2 growth factor receptor-bound protein 2 -0.0148052
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -0.0147827
FCGBP Fc fragment of IgG binding protein -0.0147557
KAT6B K(lysine) acetyltransferase 6B -0.0147525
RPS19 ribosomal protein S19 -0.0147524
BTG1 B-cell translocation gene 1, anti-proliferative -0.014747
FAM117B family with sequence similarity 117, member B -0.0147377
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -0.0147001
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.0146738
PALS2 protein associated with LIN7 2, MAGUK p55 family member -0.0146731
IMMT inner membrane protein, mitochondrial -0.0146591
ATXN2 ataxin 2 -0.0146507
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0146127
ADIPOR2 adiponectin receptor 2 -0.0146051
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0145543
KIF13A kinesin family member 13A -0.0145498
TMEM260 transmembrane protein 260 -0.0145373
PYGO1 pygopus family PHD finger 1 -0.0145317
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.0145296
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0145222
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0145079
AHCTF1 AT hook containing transcription factor 1 -0.0144897
METTL8 methyltransferase like 8 -0.0144852
GRAMD1B GRAM domain containing 1B -0.0144807
FAR1 fatty acyl CoA reductase 1 -0.0144806
SAE1 SUMO1 activating enzyme subunit 1 -0.0144578
GYS1 glycogen synthase 1 (muscle) -0.014455
BASP1 brain abundant, membrane attached signal protein 1 -0.0144466
RCC1 regulator of chromosome condensation 1 -0.0144234
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.014417
ZC3H13 zinc finger CCCH-type containing 13 -0.0144143
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0143875
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0143799
AGMO alkylglycerol monooxygenase -0.0143571
ANAPC11 anaphase promoting complex subunit 11 -0.0143039
GTPBP4 GTP binding protein 4 -0.0143031
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -0.0142968
MPZ myelin protein zero -0.0142672
LGALS8 lectin, galactoside-binding, soluble, 8 -0.014227
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0142244
ANKRD33B ankyrin repeat domain 33B -0.014223
PCED1B PC-esterase domain containing 1B -0.0141963
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -0.0141915
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0141849
RPL4 ribosomal protein L4 -0.0141669
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0141626
PREPL prolyl endopeptidase-like -0.0141571
NUP98 nucleoporin 98kDa -0.0141569
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0141563
LETMD1 LETM1 domain containing 1 -0.0141547
COL4A5 collagen, type IV, alpha 5 -0.0141475
WDR45B WD repeat domain 45B -0.0141458
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0141061
ATP9A ATPase, class II, type 9A -0.0140859
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -0.0140506
RNF213 ring finger protein 213 -0.0140505
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0140473
RAI14 retinoic acid induced 14 -0.0140315
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0140283
GRAMD1A GRAM domain containing 1A -0.0140206
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0140071
CASP8 caspase 8, apoptosis-related cysteine peptidase -0.013999
ZNF655 zinc finger protein 655 -0.0139951
WDR44 WD repeat domain 44 -0.0139787
USP32 ubiquitin specific peptidase 32 -0.0139663
PBX3 pre-B-cell leukemia homeobox 3 -0.0139516
PIF1 PIF1 5'-to-3' DNA helicase -0.0139404
PEX14 peroxisomal biogenesis factor 14 -0.0139321
IDE insulin-degrading enzyme -0.0139265
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0139201
MPZL1 myelin protein zero-like 1 -0.0138969
USP33 ubiquitin specific peptidase 33 -0.0138853
USP53 ubiquitin specific peptidase 53 -0.0138371
TENT4A terminal nucleotidyltransferase 4A -0.0138304
RHOF ras homolog family member F (in filopodia) -0.0138041