A549_GSK J1_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 100nM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_GSK J1_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT8 keratin 8, type II 0.165926
NQO1 NAD(P)H dehydrogenase, quinone 1 0.114662
KRT18 keratin 18, type I 0.0982814
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0931616
NRCAM neuronal cell adhesion molecule 0.0913547
AKR1C1 aldo-keto reductase family 1, member C1 0.0861299
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0798923
UGDH UDP-glucose 6-dehydrogenase 0.0700086
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.0638045
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0616441
TKT transketolase 0.0603484
RPLP1 ribosomal protein, large, P1 0.0598639
FTL ferritin, light polypeptide 0.0597991
SMYD3 SET and MYND domain containing 3 0.0595332
PKM pyruvate kinase, muscle 0.0595059
ACTN4 actinin, alpha 4 0.0590613
S100A10 S100 calcium binding protein A10 0.0578448
MACF1 microtubule-actin crosslinking factor 1 0.0564558
GPX2 glutathione peroxidase 2 0.0542548
MYO10 myosin X 0.0490565
UBC ubiquitin C 0.0487651
AGR2 anterior gradient 2 0.048431
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0481087
ZNF207 zinc finger protein 207 0.0462069
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0451388
AKR1C2 aldo-keto reductase family 1, member C2 0.0449363
MPG N-methylpurine-DNA glycosylase 0.0436042
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0435733
BRI3BP BRI3 binding protein 0.0432535
KRT7 keratin 7, type II 0.0430893
FAM107B family with sequence similarity 107, member B 0.0430507
RNF43 ring finger protein 43 0.0429268
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.042549
PLEC plectin 0.0422852
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.0421049
TOP2A topoisomerase (DNA) II alpha 170kDa 0.041298
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0412153
TXNRD1 thioredoxin reductase 1 0.0411054
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.040755
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0407515
KTN1 kinectin 1 (kinesin receptor) 0.0407396
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0406837
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.0403982
NSD2 nuclear receptor binding SET domain protein 2 0.0397036
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0393967
ANXA2 annexin A2 0.0392735
NEBL nebulette 0.0387632
MKI67 marker of proliferation Ki-67 0.038575
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.0382286
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0380374
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.0374492
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0373592
VEZT vezatin, adherens junctions transmembrane protein 0.0371505
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.037073
BASP1 brain abundant, membrane attached signal protein 1 0.0369025
PARD3 par-3 family cell polarity regulator 0.0368164
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0366938
USP9X ubiquitin specific peptidase 9, X-linked 0.0363437
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0360964
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0359178
HNF1A HNF1 homeobox A 0.0357775
NCAPD2 non-SMC condensin I complex, subunit D2 0.0357745
RPS29 ribosomal protein S29 0.0350051
ZRANB3 zinc finger, RAN-binding domain containing 3 0.0349877
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0349426
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0345533
GRAMD1B GRAM domain containing 1B 0.034409
MYOF myoferlin 0.0343336
GLIS3 GLIS family zinc finger 3 0.0340439
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0336431
FOXM1 forkhead box M1 0.0335634
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0334361
KIF18B kinesin family member 18B 0.0334123
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0332514
CANX calnexin 0.0331882
MGST3 microsomal glutathione S-transferase 3 0.0327894
SLIT3 slit homolog 3 (Drosophila) 0.0324274
GPC6 glypican 6 0.0323296
LAMB1 laminin, beta 1 0.0319756
RRM1 ribonucleotide reductase M1 0.0318499
KDM4C lysine (K)-specific demethylase 4C 0.0318454
CENPF centromere protein F, 350/400kDa 0.0316862
USP34 ubiquitin specific peptidase 34 0.0315385
LMAN1 lectin, mannose-binding, 1 0.0309496
GSK3B glycogen synthase kinase 3 beta 0.030338
USP32 ubiquitin specific peptidase 32 0.0300574
FXYD5 FXYD domain containing ion transport regulator 5 0.0298527
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0294173
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.0293152
RPLP2 ribosomal protein, large, P2 0.0291694
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.0291329
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0290897
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0289947
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0286963
RTN4 reticulon 4 0.0285933
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0285581
ACLY ATP citrate lyase 0.0285273
SERTAD2 SERTA domain containing 2 0.0282714
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0281039
RNASE3 ribonuclease, RNase A family, 3 0.0280746
STXBP4 syntaxin binding protein 4 0.0275623
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.027299
SOCS4 suppressor of cytokine signaling 4 0.0272207
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.027161
ANXA1 annexin A1 0.0269343
SEPTIN9 septin 9 0.0266309
SMC4 structural maintenance of chromosomes 4 0.02657
KDM5A lysine (K)-specific demethylase 5A 0.0265553
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0264949
NUP107 nucleoporin 107kDa 0.0264761
FAF1 Fas (TNFRSF6) associated factor 1 0.0264156
TUBB tubulin, beta class I 0.026075
NQO2 NAD(P)H dehydrogenase, quinone 2 0.0259558
TAGLN2 transgelin 2 0.0258991
BLTP2 bridge-like lipid transfer protein family member 2 0.0258264
RPL37 ribosomal protein L37 0.0257751
CENPE centromere protein E, 312kDa 0.0257202
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.0256604
FLOT2 flotillin 2 0.0252837
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0252644
TK1 thymidine kinase 1, soluble 0.0251376
RECQL RecQ helicase-like 0.0250854
GCLC glutamate-cysteine ligase, catalytic subunit 0.025009
PTMA prothymosin, alpha 0.0248888
RPL39 ribosomal protein L39 0.0248123
MCM4 minichromosome maintenance complex component 4 0.0244347
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0243139
MPRIP myosin phosphatase Rho interacting protein 0.0242388
DHCR7 7-dehydrocholesterol reductase 0.0241945
CCDC88A coiled-coil domain containing 88A 0.0237528
ATAD5 ATPase family, AAA domain containing 5 0.0236523
EREG epiregulin 0.023608
VCP valosin containing protein 0.0235725
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0235264
CHD9 chromodomain helicase DNA binding protein 9 0.0234291
ZMYND8 zinc finger, MYND-type containing 8 0.0234162
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0233403
SERBP1 SERPINE1 mRNA binding protein 1 0.0232762
NCKAP1 NCK-associated protein 1 0.0232277
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0231294
ABTB3 ankyrin repeat and BTB domain containing 3 0.0230543
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0230014
CD81 CD81 molecule 0.0229547
RPS3 ribosomal protein S3 0.0228733
MUSK muscle, skeletal, receptor tyrosine kinase 0.0228062
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.0227328
PRDX5 peroxiredoxin 5 0.0227242
PUF60 poly-U binding splicing factor 60KDa 0.0226295
CALU calumenin 0.0226217
MOB1B MOB kinase activator 1B 0.0224693
CCND3 cyclin D3 0.0224645
FMNL2 formin-like 2 0.0223977
PITRM1 pitrilysin metallopeptidase 1 0.0223734
KIDINS220 kinase D-interacting substrate, 220kDa 0.022315
FER fer (fps/fes related) tyrosine kinase 0.0222686
RPL4 ribosomal protein L4 0.0222169
MED13 mediator complex subunit 13 0.0222004
ATXN10 ataxin 10 0.0221361
TUBD1 tubulin, delta 1 0.0220901
CCAR1 cell division cycle and apoptosis regulator 1 0.0219785
KIF3C kinesin family member 3C 0.0219623
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0218686
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.0218477
LMNA lamin A/C 0.021764
CYB5R3 cytochrome b5 reductase 3 0.0217611
ABHD12 abhydrolase domain containing 12 0.0217532
TUBA1B tubulin, alpha 1b 0.0216902
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0216678
CADPS2 Ca++-dependent secretion activator 2 0.0216371
RUSC2 RUN and SH3 domain containing 2 0.0215937
ARHGAP11A Rho GTPase activating protein 11A 0.0215443
ADRA1B adrenoceptor alpha 1B 0.0214761
ERBIN erbb2 interacting protein 0.0214185
LYPLA1 lysophospholipase I 0.021349
TTC21B tetratricopeptide repeat domain 21B 0.0213373
ZC3H13 zinc finger CCCH-type containing 13 0.0212805
SRPK2 SRSF protein kinase 2 0.0212692
WDR33 WD repeat domain 33 0.0212668
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0212614
OSMR oncostatin M receptor 0.0212416
PON2 paraoxonase 2 0.0212392
GSTP1 glutathione S-transferase pi 1 0.0212229
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0212157
MTX2 metaxin 2 0.0211895
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.0211538
ZRANB1 zinc finger, RAN-binding domain containing 1 0.0211283
ERICH1 glutamate-rich 1 0.0211035
FOCAD focadhesin 0.0210474
SRRM2 serine/arginine repetitive matrix 2 0.0210304
SELENOI selenoprotein I 0.0210025
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.0209865
SLC35F6 solute carrier family 35, member F6 0.0209335
EIF4B eukaryotic translation initiation factor 4B 0.0208452
GSPT1 G1 to S phase transition 1 0.0207673
EIF4E eukaryotic translation initiation factor 4E 0.0207307
UBL4A ubiquitin-like 4A 0.0207164
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.020715
S100A4 S100 calcium binding protein A4 0.0206436
DPY19L1 dpy-19-like 1 (C. elegans) 0.0206228
SMIM44 small integral membrane protein 44 0.0206032
XPO1 exportin 1 0.0204674
SUMO2 small ubiquitin-like modifier 2 0.0203321
DAND5 DAN domain family member 5, BMP antagonist 0.0203035
ATXN2 ataxin 2 0.0202759
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0201974
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0201897
JAG1 jagged 1 0.0201889
CARMIL1 capping protein regulator and myosin 1 linker 1 0.0201798
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0201391
SETD7 SET domain containing (lysine methyltransferase) 7 0.0201261
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.0200674
MTMR14 myotubularin related protein 14 0.0200584
NIBAN2 niban apoptosis regulator 2 0.0200129
PRKCE protein kinase C, epsilon 0.0199456
TCF25 transcription factor 25 (basic helix-loop-helix) 0.0199439
SDC1 syndecan 1 0.0199429
PRNP prion protein 0.0199243
NRBP1 nuclear receptor binding protein 1 0.0198556
GALM galactose mutarotase (aldose 1-epimerase) 0.0197747
PRC1 protein regulator of cytokinesis 1 0.0197313
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0196425
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.0196135
SYTL2 synaptotagmin-like 2 0.0196099
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0196069
YAP1 Yes-associated protein 1 0.0195976
ELOVL6 ELOVL fatty acid elongase 6 0.0195494
TM4SF1 transmembrane 4 L six family member 1 0.0194785
SND1 staphylococcal nuclease and tudor domain containing 1 0.0194567
ATG5 autophagy related 5 0.0194196
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0193782
STX8 syntaxin 8 0.0193467
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.0192725
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.0192239
NRP1 neuropilin 1 0.0191939
HGD homogentisate 1,2-dioxygenase 0.0191042
MTCH2 mitochondrial carrier 2 0.0190949
RDX radixin 0.0190869
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.0190535
FNBP1L formin binding protein 1-like 0.0189649
ATF7IP activating transcription factor 7 interacting protein 0.0189596
RAN RAN, member RAS oncogene family 0.0189568
AHCYL2 adenosylhomocysteinase-like 2 0.01893
BRCA1 breast cancer 1, early onset 0.0189286
ZNF75A zinc finger protein 75a 0.0188548
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0188419
UBE3C ubiquitin protein ligase E3C 0.0188127
TSC22D1 TSC22 domain family, member 1 0.0188041
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0187149
ADGRG6 adhesion G protein-coupled receptor G6 0.0187126
CD63 CD63 molecule 0.018641
RAB10 RAB10, member RAS oncogene family 0.0186291
GNS glucosamine (N-acetyl)-6-sulfatase 0.0185417
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.0185309
FBXW11 F-box and WD repeat domain containing 11 0.0184339
DST dystonin 0.018405
IER5L immediate early response 5-like 0.018289
TBC1D4 TBC1 domain family, member 4 0.0182329
DYM dymeclin 0.018221
TRAP1 TNF receptor-associated protein 1 0.0181623
SLTM SAFB-like, transcription modulator 0.0181369
RNF38 ring finger protein 38 0.0181358
NCEH1 neutral cholesterol ester hydrolase 1 0.0180897
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0180633
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.0180448
TRIM56 tripartite motif containing 56 0.0180408
SKAP2 src kinase associated phosphoprotein 2 0.01804
NCOA7 nuclear receptor coactivator 7 0.0179917
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.0179721
MYO9A myosin IXA 0.0179099
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.017879
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0178051
TGOLN2 trans-golgi network protein 2 0.0177944
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0177853
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.0177397
H1-10 H1.10 linker histone 0.0176874
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0176432
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.0176383
CEP350 centrosomal protein 350kDa 0.0176297
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0176166
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.0176104
MDM4 MDM4, p53 regulator 0.0175686
TUBGCP5 tubulin, gamma complex associated protein 5 0.0175583
RBBP6 retinoblastoma binding protein 6 0.0174953
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.0174814
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0174688
DOCK7 dedicator of cytokinesis 7 0.017464
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0174564
DPYSL2 dihydropyrimidinase-like 2 0.0174259
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 0.0173341
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0173186
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0173084
FDXR ferredoxin reductase 0.0172709
COPS3 COP9 signalosome subunit 3 0.0172118
DCAF7 DDB1 and CUL4 associated factor 7 0.0172072
EMP2 epithelial membrane protein 2 0.0171963
SFT2D2 SFT2 domain containing 2 0.0171811
PFN1 profilin 1 0.0171712
FGFR1 fibroblast growth factor receptor 1 0.0171612
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0171455
TLK1 tousled-like kinase 1 0.0171326
MRPL17 mitochondrial ribosomal protein L17 0.0170673
MBNL1 muscleblind-like splicing regulator 1 0.0170652
HSPG2 heparan sulfate proteoglycan 2 0.0170147
KLHL29 kelch-like family member 29 0.016997
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.0169518
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0169435
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.0168845
CCNY cyclin Y 0.0168775
ZMYND11 zinc finger, MYND-type containing 11 0.0168402
RBM15 RNA binding motif protein 15 0.0168348
FLNB filamin B, beta 0.0168147
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.0167899
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0167888
RPL36 ribosomal protein L36 0.0167553
MFSD6 major facilitator superfamily domain containing 6 0.0167135
IQCB1 IQ motif containing B1 0.0166964
AMBRA1 autophagy/beclin-1 regulator 1 0.0166706
TMPO thymopoietin 0.0166635
ACBD6 acyl-CoA binding domain containing 6 0.0166429
UROS uroporphyrinogen III synthase 0.0165982
VDAC3 voltage-dependent anion channel 3 0.0165895
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0165879
SPTSSA serine palmitoyltransferase, small subunit A 0.016586
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.0165454
ERLIN2 ER lipid raft associated 2 0.0165443
ILF3 interleukin enhancer binding factor 3, 90kDa 0.0165412
GPATCH8 G patch domain containing 8 0.0165105
ADIPOR2 adiponectin receptor 2 0.0164911
DHCR24 24-dehydrocholesterol reductase 0.0164546
TUT4 terminal uridylyl transferase 4 0.0164216
CDC73 cell division cycle 73 0.0163893
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.0163886
COLGALT1 collagen beta(1-O)galactosyltransferase 1 0.0163721
FOXO1 forkhead box O1 0.0163559
ADPGK ADP-dependent glucokinase 0.0163522
HP1BP3 heterochromatin protein 1, binding protein 3 0.016341
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.0163381
MIDN midnolin 0.0163192
NUP133 nucleoporin 133kDa 0.016307
ACBD5 acyl-CoA binding domain containing 5 0.016263
MAP2K1 mitogen-activated protein kinase kinase 1 0.0162593
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0162575
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0162518
STK4 serine/threonine kinase 4 0.0162064
ERCC3 excision repair cross-complementation group 3 0.0161826
INTS2 integrator complex subunit 2 0.0161681
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 0.0161458
OSBPL9 oxysterol binding protein-like 9 0.0161426
DNPEP aspartyl aminopeptidase 0.0161176
WWC3 WWC family member 3 0.0160741
CUL1 cullin 1 0.016057
BZW2 basic leucine zipper and W2 domains 2 0.0160238
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.0159931
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 0.0159913
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.0159812
MED15 mediator complex subunit 15 0.0159795
RAB7A RAB7A, member RAS oncogene family 0.0159507
TMCO1 transmembrane and coiled-coil domains 1 0.0159214
EXOC6B exocyst complex component 6B 0.0158786
EIF5B eukaryotic translation initiation factor 5B 0.0158642
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0158384
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0158169
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0157971
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0157419
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0157376
DIAPH1 diaphanous-related formin 1 0.0157343
MTIF2 mitochondrial translational initiation factor 2 0.0157172
ARHGAP18 Rho GTPase activating protein 18 0.015676
SMAD6 SMAD family member 6 0.0156409
RTN3 reticulon 3 0.0156372
UBTD2 ubiquitin domain containing 2 0.0156172
TMEM245 transmembrane protein 245 0.015595
INSR insulin receptor 0.0155739
TULP3 tubby like protein 3 0.015562
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.015537
VAC14 Vac14 homolog (S. cerevisiae) 0.0155335
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0155316
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.0155305
ADISSP adipose secreted signaling protein 0.015529
SIL1 SIL1 nucleotide exchange factor 0.015528
DSN1 DSN1, MIS12 kinetochore complex component 0.0155098
PRDX4 peroxiredoxin 4 0.0154987
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0154901
TUSC3 tumor suppressor candidate 3 0.0154872
STAU1 staufen double-stranded RNA binding protein 1 0.0154378
DENR density-regulated protein 0.0154369
ATP13A3 ATPase type 13A3 0.0154286
GMDS GDP-mannose 4,6-dehydratase 0.0154059
ACTN1 actinin, alpha 1 0.0153969
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.0153964
P4HB prolyl 4-hydroxylase, beta polypeptide 0.015382
EXOC5 exocyst complex component 5 0.015365
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0153416
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.0153272
AFF4 AF4/FMR2 family, member 4 0.0153074
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0152631
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0152502
KARS1 lysyl-tRNA synthetase 1 0.0151988
SSR4 signal sequence receptor, delta 0.0151887
IQGAP1 IQ motif containing GTPase activating protein 1 0.0151774
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.0151555
FANCL Fanconi anemia, complementation group L 0.0151546
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 0.0151449
EMC3 ER membrane protein complex subunit 3 0.0151423
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0151022
DGKD diacylglycerol kinase, delta 130kDa 0.0150963
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0150927
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.0150846
PGM2L1 phosphoglucomutase 2-like 1 0.015056
GLI2 GLI family zinc finger 2 0.0150452
CNTNAP3 contactin associated protein-like 3 0.0150436
POLK polymerase (DNA directed) kappa 0.0150364
H2AZ2 H2A.Z variant histone 2 0.0150233
FBXW8 F-box and WD repeat domain containing 8 0.0150128
ARID1A AT rich interactive domain 1A (SWI-like) 0.0149774
SGO1 shugoshin 1 0.0149463
ZNF106 zinc finger protein 106 0.0149007
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.0148964
WDR45B WD repeat domain 45B 0.0148882
DMTN dematin actin binding protein 0.0148835
PM20D1 peptidase M20 domain containing 1 0.0148755
TICRR TOPBP1-interacting checkpoint and replication regulator 0.0148691
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 0.0148182
TGFB2 transforming growth factor, beta 2 0.0148056
CNTROB centrobin, centrosomal BRCA2 interacting protein 0.0147723
NOVA1 neuro-oncological ventral antigen 1 0.0147641
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0147198
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.014711
GDNF glial cell derived neurotrophic factor 0.0146958
MICU1 mitochondrial calcium uptake 1 0.0146808
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0146801
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.014678
ATF7IP2 activating transcription factor 7 interacting protein 2 0.0146173
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.0146105
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0145997
HDAC4 histone deacetylase 4 0.0145944
TPST1 tyrosylprotein sulfotransferase 1 0.0145894
SFPQ splicing factor proline/glutamine-rich 0.014564
ZBTB25 zinc finger and BTB domain containing 25 0.0145611
EPHA2 EPH receptor A2 0.0145517
COTL1 coactosin-like F-actin binding protein 1 0.0145347
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0145339
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0145149
LBR lamin B receptor 0.0145087
FBXO34 F-box protein 34 0.014488
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.014465
GEMIN5 gem (nuclear organelle) associated protein 5 0.0144639
NCOA6 nuclear receptor coactivator 6 0.0144579
RBM10 RNA binding motif protein 10 0.0144463
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0144448
GOLGA8B golgin A8 family, member B 0.0144284
TMSB10 thymosin beta 10 0.0144065
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0143741
CNST consortin, connexin sorting protein 0.0143534
PSPC1 paraspeckle component 1 0.0143319
SMTN smoothelin 0.0143225
RICTOR RPTOR independent companion of MTOR, complex 2 0.0142893
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.0142782
WDR82 WD repeat domain 82 0.0142529
ZDHHC5 zinc finger, DHHC-type containing 5 0.0142459
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.0142353
FADS2 fatty acid desaturase 2 0.0141857
BLZF1 basic leucine zipper nuclear factor 1 0.014174
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.0141667
PRR12 proline rich 12 0.0141439
TPD52L1 tumor protein D52-like 1 0.0141323
NCS1 neuronal calcium sensor 1 0.0141319
BICD1 bicaudal D homolog 1 (Drosophila) 0.0141197
NCAPG2 non-SMC condensin II complex, subunit G2 0.0141059
PDE8A phosphodiesterase 8A 0.0140947
GTSE1 G-2 and S-phase expressed 1 0.0140873
DEK DEK proto-oncogene 0.0140654
TSLIG1 tRNA splicing ligase complex subunit 1 0.0140607
ATP9B ATPase, class II, type 9B 0.0140295
GOLIM4 golgi integral membrane protein 4 0.0139987
RC3H1 ring finger and CCCH-type domains 1 0.0139857
ATL3 atlastin GTPase 3 0.0139792
MON2 MON2 homolog (S. cerevisiae) 0.0139778
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.013961
SYNJ2 synaptojanin 2 0.0139585
NPC1 Niemann-Pick disease, type C1 0.0139583
MGME1 mitochondrial genome maintenance exonuclease 1 0.0139159
SIGMAR1 sigma non-opioid intracellular receptor 1 0.0139123
MXRA7 matrix-remodelling associated 7 0.0139044
CLIC1 chloride intracellular channel 1 0.0138859
MECP2 methyl CpG binding protein 2 0.0138799
TSPAN3 tetraspanin 3 0.0138599
RDH10 retinol dehydrogenase 10 (all-trans) 0.0138347
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.0138096
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.013796
PACS1 phosphofurin acidic cluster sorting protein 1 0.0137802
KDM7A lysine (K)-specific demethylase 7A 0.0137747
LMNB2 lamin B2 0.0137612
KYAT3 kynurenine aminotransferase 3 0.0137441
PARP1 poly (ADP-ribose) polymerase 1 0.0137402
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.0137258
SMOX spermine oxidase 0.0137241
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.013721
FAM199X family with sequence similarity 199, X-linked 0.0137207
EED embryonic ectoderm development 0.0137078

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.0972327
PDE4D phosphodiesterase 4D, cAMP-specific -0.0929508
ARHGAP26 Rho GTPase activating protein 26 -0.089508
ZBTB20 zinc finger and BTB domain containing 20 -0.075666
CA12 carbonic anhydrase XII -0.074424
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0728271
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.06958
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0687917
CUX1 cut-like homeobox 1 -0.0665068
CNTN1 contactin 1 -0.0642116
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0627915
KIFC3 kinesin family member C3 -0.0613016
KYNU kynureninase -0.0574536
TTC28 tetratricopeptide repeat domain 28 -0.0567179
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0554664
TMOD3 tropomodulin 3 (ubiquitous) -0.052954
HDLBP high density lipoprotein binding protein -0.0525017
EHBP1 EH domain binding protein 1 -0.0522164
RPS2 ribosomal protein S2 -0.0521697
LPP LIM domain containing preferred translocation partner in lipoma -0.0510834
BRD4 bromodomain containing 4 -0.0495986
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0491447
ENO1 enolase 1, (alpha) -0.0489857
LRMDA leucine rich melanocyte differentiation associated -0.0485649
RPS6 ribosomal protein S6 -0.0481344
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0478625
SSH2 slingshot protein phosphatase 2 -0.0472712
CTSD cathepsin D -0.0470733
FHIT fragile histidine triad -0.0467114
NCOA3 nuclear receptor coactivator 3 -0.0447347
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0446809
SMAD2 SMAD family member 2 -0.0439475
FGG fibrinogen gamma chain -0.043407
NTN4 netrin 4 -0.0430558
AGFG1 ArfGAP with FG repeats 1 -0.0425981
BMPR1B bone morphogenetic protein receptor, type IB -0.042152
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0416358
RPL29 ribosomal protein L29 -0.0409723
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0404994
DOCK5 dedicator of cytokinesis 5 -0.0396483
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0388233
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0387941
RIOK3 RIO kinase 3 -0.0385851
IGFBP4 insulin-like growth factor binding protein 4 -0.0385228
PSD3 pleckstrin and Sec7 domain containing 3 -0.0377614
PPP1R9A protein phosphatase 1, regulatory subunit 9A -0.0369661
APP amyloid beta (A4) precursor protein -0.0365236
TRIO trio Rho guanine nucleotide exchange factor -0.0364624
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0363783
GOLGA4 golgin A4 -0.0362587
SMAD3 SMAD family member 3 -0.035755
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0357484
ELMO1 engulfment and cell motility 1 -0.0356664
AK1 adenylate kinase 1 -0.0352021
RPN2 ribophorin II -0.0349365
EVA1C eva-1 homolog C (C. elegans) -0.0348821
ALCAM activated leukocyte cell adhesion molecule -0.0348044
BCAS3 breast carcinoma amplified sequence 3 -0.0346865
SERINC5 serine incorporator 5 -0.0344981
SLC38A10 solute carrier family 38, member 10 -0.0344324
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0342968
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0340973
DAPK1 death-associated protein kinase 1 -0.033693
AKAP12 A kinase (PRKA) anchor protein 12 -0.0331308
WWOX WW domain containing oxidoreductase -0.0326278
MTUS1 microtubule associated tumor suppressor 1 -0.0324448
EFNA5 ephrin-A5 -0.0324312
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -0.0323634
URI1 URI1, prefoldin-like chaperone -0.0322098
BPTF bromodomain PHD finger transcription factor -0.0319231
RPL8 ribosomal protein L8 -0.0316402
PLCB4 phospholipase C, beta 4 -0.0315859
PDLIM5 PDZ and LIM domain 5 -0.0315476
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0313602
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0313543
NF1 neurofibromin 1 -0.0311639
PTPRA protein tyrosine phosphatase, receptor type, A -0.0311596
CUEDC1 CUE domain containing 1 -0.0311026
MPHOSPH9 M-phase phosphoprotein 9 -0.0309915
THSD7A thrombospondin, type I, domain containing 7A -0.0309288
HIP1 huntingtin interacting protein 1 -0.0307512
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0305706
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0305559
TGFBI transforming growth factor, beta-induced, 68kDa -0.0303791
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0302391
UBE2H ubiquitin-conjugating enzyme E2H -0.0301521
ZFAND6 zinc finger, AN1-type domain 6 -0.0300955
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0300811
SQSTM1 sequestosome 1 -0.0299321
BICC1 BicC family RNA binding protein 1 -0.0298187
RIN2 Ras and Rab interactor 2 -0.0297391
DENND4A DENN/MADD domain containing 4A -0.0297157
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.029573
PRDX1 peroxiredoxin 1 -0.0295396
SEC11A SEC11 homolog A (S. cerevisiae) -0.0294491
COG5 component of oligomeric golgi complex 5 -0.0294279
ECPAS Ecm29 proteasome adaptor and scaffold -0.0293878
TBC1D14 TBC1 domain family, member 14 -0.0293499
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -0.0293118
NOSTRIN nitric oxide synthase trafficking -0.0290547
FNDC3B fibronectin type III domain containing 3B -0.0288297
ATXN1 ataxin 1 -0.0284828
AUTS2 autism susceptibility candidate 2 -0.0283211
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0282282
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.028194
NAP1L1 nucleosome assembly protein 1-like 1 -0.0281896
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0281684
RHOBTB1 Rho-related BTB domain containing 1 -0.0280975
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0280671
CMIP c-Maf inducing protein -0.0277376
ECI1 enoyl-CoA delta isomerase 1 -0.0275922
SLC38A1 solute carrier family 38, member 1 -0.0273562
WDR43 WD repeat domain 43 -0.0270995
AATF apoptosis antagonizing transcription factor -0.0269602
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.0268393
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0268302
NUMB numb homolog (Drosophila) -0.0267614
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0267304
MLXIP MLX interacting protein -0.0266363
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.0265101
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0264485
SNAP25 synaptosomal-associated protein, 25kDa -0.0264373
ATP5MC2 ATP synthase membrane subunit c locus 2 -0.0263934
NEB nebulin -0.0263903
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0262555
RNF145 ring finger protein 145 -0.0262186
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0261279
PTPRK protein tyrosine phosphatase, receptor type, K -0.0259825
ARL15 ADP-ribosylation factor-like 15 -0.0259673
CLTC clathrin, heavy chain (Hc) -0.0258338
PPARG peroxisome proliferator-activated receptor gamma -0.0257529
ZFR zinc finger RNA binding protein -0.0256748
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0256568
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.02543
KMT2C lysine (K)-specific methyltransferase 2C -0.0252828
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0252808
DNAAF9 dynein axonemal assembly factor 9 -0.0252336
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0251397
MACROD2 MACRO domain containing 2 -0.0250708
FOXP1 forkhead box P1 -0.0250681
IQGAP2 IQ motif containing GTPase activating protein 2 -0.0250169
USP53 ubiquitin specific peptidase 53 -0.0249989
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -0.0249762
TXNDC11 thioredoxin domain containing 11 -0.0248772
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -0.0248316
AOPEP aminopeptidase O (putative) -0.0247446
TASOR2 transcription activation suppressor family member 2 -0.0245829
SLC39A11 solute carrier family 39, member 11 -0.0245736
STK32B serine/threonine kinase 32B -0.0244682
PKN2 protein kinase N2 -0.0244536
ZNRF3 zinc and ring finger 3 -0.0243216
KIF3B kinesin family member 3B -0.0242777
TFRC transferrin receptor -0.0242776
NBEAL1 neurobeachin-like 1 -0.0242619
PUM2 pumilio RNA-binding family member 2 -0.0242604
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0242413
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0241835
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0240926
SOS1 son of sevenless homolog 1 (Drosophila) -0.0240675
BRWD3 bromodomain and WD repeat domain containing 3 -0.0240371
THSD4 thrombospondin, type I, domain containing 4 -0.0239793
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0239278
CORO1C coronin, actin binding protein, 1C -0.0237677
AAK1 AP2 associated kinase 1 -0.0237361
OPHN1 oligophrenin 1 -0.0236741
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0235664
ARHGAP5 Rho GTPase activating protein 5 -0.0234876
RBPMS RNA binding protein with multiple splicing -0.0233626
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0233565
HDGF hepatoma-derived growth factor -0.0232744
RHOT1 ras homolog family member T1 -0.0232183
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0232067
ATE1 arginyltransferase 1 -0.0231478
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0230773
LGSN lengsin, lens protein with glutamine synthetase domain -0.0229799
CRTC3 CREB regulated transcription coactivator 3 -0.0229765
RPS11 ribosomal protein S11 -0.0228344
MSH3 mutS homolog 3 -0.0228259
CEMIP2 cell migration inducing hyaluronidase 2 -0.0228211
GLG1 golgi glycoprotein 1 -0.0228198
BIRC6 baculoviral IAP repeat containing 6 -0.0227324
TPM1 tropomyosin 1 (alpha) -0.0227275
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0226176
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -0.0225591
SAMD4A sterile alpha motif domain containing 4A -0.0224327
MRTFA myocardin related transcription factor A -0.022381
ZNF721 zinc finger protein 721 -0.0222176
SVIL supervillin -0.0220648
TAOK1 TAO kinase 1 -0.0219561
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0219292
KMT5B lysine methyltransferase 5B -0.0219242
RPS8 ribosomal protein S8 -0.0218354
SFXN5 sideroflexin 5 -0.0217811
GCLM glutamate-cysteine ligase, modifier subunit -0.0217784
SLC38A2 solute carrier family 38, member 2 -0.0217471
DLG5 discs, large homolog 5 (Drosophila) -0.0217097
GPR135 G protein-coupled receptor 135 -0.0215916
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0215551
STK39 serine threonine kinase 39 -0.021533
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0215259
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0214887
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0214479
CDYL chromodomain protein, Y-like -0.0213596
TXN2 thioredoxin 2 -0.0213469
BAG1 BCL2-associated athanogene -0.0212926
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0212632
FRYL FRY-like -0.0211207
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0211103
KIF13A kinesin family member 13A -0.0209919
GCFC2 GC-rich sequence DNA-binding factor 2 -0.0209823
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0209613
FOXO3 forkhead box O3 -0.0209387
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0209331
BCLAF1 BCL2-associated transcription factor 1 -0.020912
MAML3 mastermind-like 3 (Drosophila) -0.0208842
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.0206061
CD46 CD46 molecule, complement regulatory protein -0.0205851
NUAK1 NUAK family, SNF1-like kinase, 1 -0.020574
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.020522
NFIB nuclear factor I/B -0.0205118
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -0.0205071
RPL32 ribosomal protein L32 -0.0204784
CD44 CD44 molecule (Indian blood group) -0.0204447
ESYT2 extended synaptotagmin-like protein 2 -0.0204276
KLF5 Kruppel-like factor 5 (intestinal) -0.0203864
TRERF1 transcriptional regulating factor 1 -0.0203541
SENP6 SUMO1/sentrin specific peptidase 6 -0.0203332
NRG1 neuregulin 1 -0.0203185
CHD1L chromodomain helicase DNA binding protein 1-like -0.0202772
ITSN1 intersectin 1 (SH3 domain protein) -0.0202676
RAP1B RAP1B, member of RAS oncogene family -0.0202658
INTS8 integrator complex subunit 8 -0.0202542
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.020219
RFX7 regulatory factor X, 7 -0.0202141
TRIP12 thyroid hormone receptor interactor 12 -0.02018
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.020175
CYSTM1 cysteine-rich transmembrane module containing 1 -0.0200414
WDR72 WD repeat domain 72 -0.0200403
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0200057
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0199897
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0199668
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -0.0199186
RACK1 receptor for activated C kinase 1 -0.0199146
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0199129
PCDHB16 protocadherin beta 16 -0.0198989
MRTFB myocardin related transcription factor B -0.0198845
C2ORF42 chromosome 2 open reading frame 42 -0.0198829
FOSL2 FOS-like antigen 2 -0.0198233
PHF21A PHD finger protein 21A -0.01982
PDE10A phosphodiesterase 10A -0.0196849
KIF2A kinesin heavy chain member 2A -0.0196818
TRIM37 tripartite motif containing 37 -0.01965
NDRG3 NDRG family member 3 -0.0196381
DCAF1 DDB1 and CUL4 associated factor 1 -0.0196173
SH3KBP1 SH3-domain kinase binding protein 1 -0.0195774
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0195769
ADGRE5 adhesion G protein-coupled receptor E5 -0.0195238
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0195081
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0195056
PTPRF protein tyrosine phosphatase, receptor type, F -0.0194732
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0194518
SMOC1 SPARC related modular calcium binding 1 -0.0194006
NBEA neurobeachin -0.0192745
VCAN versican -0.0191993
CFH complement factor H -0.0191931
VMP1 vacuole membrane protein 1 -0.019146
MOSMO modulator of smoothened -0.0191056
XRRA1 X-ray radiation resistance associated 1 -0.0190994
CTSB cathepsin B -0.0190965
METTL16 methyltransferase like 16 -0.0190848
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0190489
HMGB1 high mobility group box 1 -0.0190388
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.0190206
LIPH lipase, member H -0.0190069
SENP1 SUMO1/sentrin specific peptidase 1 -0.0189894
SKIL SKI-like proto-oncogene -0.0189664
POC1B POC1 centriolar protein B -0.0189589
MAP2K2 mitogen-activated protein kinase kinase 2 -0.0189376
ARMH3 armadillo like helical domain containing 3 -0.0189341
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.0189012
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0188823
GRB10 growth factor receptor-bound protein 10 -0.0187828
SLC35F3 solute carrier family 35, member F3 -0.0186891
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0186321
FANCA Fanconi anemia, complementation group A -0.0186143
TLN2 talin 2 -0.0186083
TACC1 transforming, acidic coiled-coil containing protein 1 -0.0185962
ASPH aspartate beta-hydroxylase -0.0185651
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -0.018433
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0183967
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.018396
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0183771
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0183054
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0182365
ETNK1 ethanolamine kinase 1 -0.0182054
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -0.0182045
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0181659
TANK TRAF family member-associated NFKB activator -0.0181444
SEC24B SEC24 family member B -0.0181402
KIAA2026 KIAA2026 -0.0181227
GEN1 GEN1 Holliday junction 5' flap endonuclease -0.0181196
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.018086
C5 complement component 5 -0.0180217
NUP160 nucleoporin 160kDa -0.0180113
DEAF1 DEAF1 transcription factor -0.018005
POTEF POTE ankyrin domain family, member F -0.017943
LTBP1 latent transforming growth factor beta binding protein 1 -0.0179277
PTGES2 prostaglandin E synthase 2 -0.0179274
TTC3 tetratricopeptide repeat domain 3 -0.0179007
RAP1GAP2 RAP1 GTPase activating protein 2 -0.0178623
HDAC8 histone deacetylase 8 -0.0178586
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0178561
ATAD2 ATPase family, AAA domain containing 2 -0.0178472
BCL2L13 BCL2-like 13 (apoptosis facilitator) -0.0178303
ITFG2 integrin alpha FG-GAP repeat containing 2 -0.0178212
KIAA1958 KIAA1958 -0.0177995
RO60 Ro60, Y RNA binding protein -0.01779
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -0.0177715
SPPL3 signal peptide peptidase like 3 -0.0177502
USP24 ubiquitin specific peptidase 24 -0.0176934
PRKX protein kinase, X-linked -0.0176871
WDR12 WD repeat domain 12 -0.0176835
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -0.0176796
LONP2 lon peptidase 2, peroxisomal -0.0176761
RAD9A RAD9 homolog A (S. pombe) -0.0176299
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0176251
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0175056
KIF13B kinesin family member 13B -0.01749
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0174848
SASH1 SAM and SH3 domain containing 1 -0.0174801
UBE3A ubiquitin protein ligase E3A -0.0174766
REEP5 receptor accessory protein 5 -0.017473
MAP4 microtubule-associated protein 4 -0.0174604
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.0174573
SUMF1 sulfatase modifying factor 1 -0.0174028
GTF2I general transcription factor IIi -0.017393
PCDH9 protocadherin 9 -0.0173789
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0173728
ABHD17C abhydrolase domain containing 17C -0.0173453
GNB5 guanine nucleotide binding protein (G protein), beta 5 -0.0172948
IPO9 importin 9 -0.0172497
DCP1A decapping mRNA 1A -0.017244
SH3PXD2A SH3 and PX domains 2A -0.0171846
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0171801
MTA3 metastasis associated 1 family, member 3 -0.017179
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0171398
ELP3 elongator acetyltransferase complex subunit 3 -0.0171301
SMC6 structural maintenance of chromosomes 6 -0.0171205
PDE7A phosphodiesterase 7A -0.0171084
WAC WW domain containing adaptor with coiled-coil -0.017097
ZNF652 zinc finger protein 652 -0.0170796
DGCR2 DiGeorge syndrome critical region gene 2 -0.0170594
MRPS27 mitochondrial ribosomal protein S27 -0.0170467
DCAF6 DDB1 and CUL4 associated factor 6 -0.0170453
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0170284
TM9SF4 transmembrane 9 superfamily protein member 4 -0.0169637
LATS2 large tumor suppressor kinase 2 -0.0169594
USP36 ubiquitin specific peptidase 36 -0.0169398
TSKU tsukushi, small leucine rich proteoglycan -0.0169347
CEP112 centrosomal protein 112kDa -0.0169174
RNF149 ring finger protein 149 -0.016863
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0167619
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0167367
WDR44 WD repeat domain 44 -0.0167207
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0167067
DYNC2I1 dynein 2 intermediate chain 1 -0.0166894
TMCC1 transmembrane and coiled-coil domain family 1 -0.0166809
SCAF11 SR-related CTD-associated factor 11 -0.016637
ARMC9 armadillo repeat containing 9 -0.016629
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.016598
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 -0.0165809
CEP95 centrosomal protein 95kDa -0.0165475
RHOF ras homolog family member F (in filopodia) -0.0165404
HSPA4 heat shock 70kDa protein 4 -0.0165299
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.0165109
EGR1 early growth response 1 -0.0164865
KDM6A lysine (K)-specific demethylase 6A -0.0164774
DNM1 dynamin 1 -0.0164608
BEND7 BEN domain containing 7 -0.0164352
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0164253
TMEM164 transmembrane protein 164 -0.0163967
CREBBP CREB binding protein -0.0163822
MZT2A mitotic spindle organizing protein 2A -0.0163626
HOOK3 hook microtubule-tethering protein 3 -0.016319
SPPL2A signal peptide peptidase like 2A -0.0163147
TTC17 tetratricopeptide repeat domain 17 -0.0162934
SCAF8 SR-related CTD-associated factor 8 -0.0162534
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0161977
SCARB1 scavenger receptor class B, member 1 -0.0161937
ZMPSTE24 zinc metallopeptidase STE24 -0.0161794
GPRIN3 GPRIN family member 3 -0.0161428
SEC23A Sec23 homolog A (S. cerevisiae) -0.0161421
ABHD3 abhydrolase domain containing 3 -0.0161312
COG4 component of oligomeric golgi complex 4 -0.0161103
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0161062
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0160735
MRRF mitochondrial ribosome recycling factor -0.0160126
HPCAL1 hippocalcin-like 1 -0.0160094
KCNT2 potassium channel, sodium activated subfamily T, member 2 -0.0159945
NCOR1 nuclear receptor corepressor 1 -0.0159932
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 -0.0159805
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0159719
SLC45A4 solute carrier family 45, member 4 -0.0159597
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase -0.0159321
MTMR3 myotubularin related protein 3 -0.0158379
NFIA nuclear factor I/A -0.0158338
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.0158225
NCOA1 nuclear receptor coactivator 1 -0.0158178
PTBP3 polypyrimidine tract binding protein 3 -0.0158023
ATM ATM serine/threonine kinase -0.0157956
TMEM87A transmembrane protein 87A -0.0157858
NCOA2 nuclear receptor coactivator 2 -0.0157798
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0157479
NSD1 nuclear receptor binding SET domain protein 1 -0.0157463
TESC tescalcin -0.0157228
CERT1 ceramide transporter 1 -0.0156972
SPRED1 sprouty-related, EVH1 domain containing 1 -0.0156941
SPAG9 sperm associated antigen 9 -0.0156907
RNF130 ring finger protein 130 -0.0156294
RPS28 ribosomal protein S28 -0.0156049
ICE2 interactor of little elongation complex ELL subunit 2 -0.0155687
TTC27 tetratricopeptide repeat domain 27 -0.0155445
FOSL1 FOS-like antigen 1 -0.0155415
DRC8 dynein regulatory complex subunit 8 -0.0155029
NIPSNAP2 nipsnap homolog 2 -0.0154468
KIAA0319L KIAA0319-like -0.0154137
NOP2 NOP2 nucleolar protein -0.015408
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0153715
SNX8 sorting nexin 8 -0.015365
RSF1 remodeling and spacing factor 1 -0.015334
ETF1 eukaryotic translation termination factor 1 -0.0153299
CHSY1 chondroitin sulfate synthase 1 -0.0152921
LRP12 low density lipoprotein receptor-related protein 12 -0.0152784
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0152294
FTO fat mass and obesity associated -0.0152065
KDM5C lysine (K)-specific demethylase 5C -0.0152051
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0151966
PCED1B PC-esterase domain containing 1B -0.0151951
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0151846
ZNF644 zinc finger protein 644 -0.0151681
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0151169
CEP85L centrosomal protein 85kDa-like -0.0150687
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0150124
VGLL4 vestigial-like family member 4 -0.0149975
WWC1 WW and C2 domain containing 1 -0.0149749
TMC5 transmembrane channel-like 5 -0.014969
BLVRB biliverdin reductase B -0.0149632
SIRAL1 SIR2 antiphage like 1 -0.0149576
PHACTR2 phosphatase and actin regulator 2 -0.0149545
RAB6A RAB6A, member RAS oncogene family -0.0149322
RABGAP1 RAB GTPase activating protein 1 -0.0149238
POLE polymerase (DNA directed), epsilon, catalytic subunit -0.0149137
STK24 serine/threonine kinase 24 -0.0148954
PDS5A PDS5 cohesin associated factor A -0.014868
GRB14 growth factor receptor-bound protein 14 -0.014849
ASL argininosuccinate lyase -0.0148268
PAXBP1 PAX3 and PAX7 binding protein 1 -0.014826
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0148162
HKDC1 hexokinase domain containing 1 -0.0148041
TGIF1 TGFB-induced factor homeobox 1 -0.0147912
AXL AXL receptor tyrosine kinase -0.0147768
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0146898
USP48 ubiquitin specific peptidase 48 -0.0146781
RAB12 RAB12, member RAS oncogene family -0.0146722
PLCH1 phospholipase C, eta 1 -0.0146699
TTC19 tetratricopeptide repeat domain 19 -0.014669
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 -0.0146572
WWC2 WW and C2 domain containing 2 -0.0146549
IL6ST interleukin 6 signal transducer -0.014645
MTDH metadherin -0.0146439
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0146383
SARAF store-operated calcium entry-associated regulatory factor -0.014635
CD2AP CD2-associated protein -0.014616
ZFP91 ZFP91 zinc finger protein -0.0145533
TMED3 transmembrane emp24 protein transport domain containing 3 -0.0145481
MON1B MON1 secretory trafficking family member B -0.014516
RIC1 RAB6A GEF complex partner 1 -0.014501
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0144871
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 -0.0144826
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0144814
PWP1 PWP1 homolog (S. cerevisiae) -0.0144803
ELOVL5 ELOVL fatty acid elongase 5 -0.0144584
TPM4 tropomyosin 4 -0.0144392
SZRD1 SUZ RNA binding domain containing 1 -0.0144314
DOCK1 dedicator of cytokinesis 1 -0.0144163
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0143842
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0143584
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.0143398
SCARA5 scavenger receptor class A, member 5 -0.0143285
ARF4 ADP-ribosylation factor 4 -0.0142872
UBXN4 UBX domain protein 4 -0.0142644
LPAR1 lysophosphatidic acid receptor 1 -0.0142372
ATXN3 ataxin 3 -0.0142229
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0142139
SNX4 sorting nexin 4 -0.014205
DSCAML1 Down syndrome cell adhesion molecule like 1 -0.0142013
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.0141874
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0141726
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -0.0141639
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0141452