A549_GSK J1_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description GSK J1 10nM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_GSK J1_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT8 keratin 8, type II 0.255882
FTL ferritin, light polypeptide 0.174603
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.14685
KRT18 keratin 18, type I 0.101167
KRT81 keratin 81, type II 0.0924683
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0904454
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0805723
AKR1C3 aldo-keto reductase family 1, member C3 0.0760189
AKR1C2 aldo-keto reductase family 1, member C2 0.0759947
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0716556
UBL4A ubiquitin-like 4A 0.0606588
SPTBN1 spectrin, beta, non-erythrocytic 1 0.060317
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.059954
TPI1 triosephosphate isomerase 1 0.0575455
FLNA filamin A, alpha 0.0567163
RPLP1 ribosomal protein, large, P1 0.052681
AKR1C1 aldo-keto reductase family 1, member C1 0.0518641
GPX2 glutathione peroxidase 2 0.0503295
PHGDH phosphoglycerate dehydrogenase 0.0473003
SMIM44 small integral membrane protein 44 0.047053
PKM pyruvate kinase, muscle 0.0468514
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0434478
CEP350 centrosomal protein 350kDa 0.0412442
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0389095
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.038535
ZFHX3 zinc finger homeobox 3 0.0382479
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0381488
SSH2 slingshot protein phosphatase 2 0.0376605
FAM13A family with sequence similarity 13, member A 0.0372653
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0372421
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0371288
MUSK muscle, skeletal, receptor tyrosine kinase 0.0365692
RNF38 ring finger protein 38 0.0363621
THADA thyroid adenoma associated 0.0360083
NCAPD2 non-SMC condensin I complex, subunit D2 0.0359674
ACTG1 actin gamma 1 0.0353297
LMAN2 lectin, mannose-binding 2 0.0351337
TPR translocated promoter region, nuclear basket protein 0.0350782
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0346876
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0337589
ARHGAP35 Rho GTPase activating protein 35 0.0335185
PLEC plectin 0.0332818
PCYOX1 prenylcysteine oxidase 1 0.0332617
GSK3B glycogen synthase kinase 3 beta 0.0331718
RPL23 ribosomal protein L23 0.0331691
FN1 fibronectin 1 0.0326368
PCNX2 pecanex 2 0.0325603
FLNB filamin B, beta 0.0322903
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0319854
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0319171
MKI67 marker of proliferation Ki-67 0.0315302
BRCA1 breast cancer 1, early onset 0.0310506
GSPT1 G1 to S phase transition 1 0.0304937
ACTN4 actinin, alpha 4 0.0304184
RACK1 receptor for activated C kinase 1 0.0301771
ECPAS Ecm29 proteasome adaptor and scaffold 0.0301602
TRAM1 translocation associated membrane protein 1 0.0299825
HDLBP high density lipoprotein binding protein 0.0297711
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0295018
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0291714
TLN1 talin 1 0.0291276
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.029071
RBM47 RNA binding motif protein 47 0.0289859
NFIB nuclear factor I/B 0.0289085
KPNB1 karyopherin (importin) beta 1 0.0287568
FADS2 fatty acid desaturase 2 0.0285926
TUBA1B tubulin, alpha 1b 0.028442
ALMS1 Alstrom syndrome protein 1 0.0282973
RPS19 ribosomal protein S19 0.0282259
CCDC88A coiled-coil domain containing 88A 0.0279858
DCTN4 dynactin 4 (p62) 0.0277887
EGFR epidermal growth factor receptor 0.0276906
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0276146
SDC1 syndecan 1 0.0273767
UBB ubiquitin B 0.027298
AHNAK2 AHNAK nucleoprotein 2 0.0272566
EIF3B eukaryotic translation initiation factor 3, subunit B 0.026773
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0266052
RPL38 ribosomal protein L38 0.0265733
TRIM28 tripartite motif containing 28 0.0265397
LONP2 lon peptidase 2, peroxisomal 0.0264042
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.026155
UBE3C ubiquitin protein ligase E3C 0.0256405
BCAP31 B-cell receptor-associated protein 31 0.0255872
PUF60 poly-U binding splicing factor 60KDa 0.0255683
KIF3C kinesin family member 3C 0.0255473
ACACA acetyl-CoA carboxylase alpha 0.0254521
AKAP13 A kinase (PRKA) anchor protein 13 0.0253398
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0252005
TMSB10 thymosin beta 10 0.0249703
RPL30 ribosomal protein L30 0.0247484
ASXL2 additional sex combs like transcriptional regulator 2 0.0244132
COPA coatomer protein complex, subunit alpha 0.0242787
EVA1C eva-1 homolog C (C. elegans) 0.0241311
PIBF1 progesterone immunomodulatory binding factor 1 0.0239463
ADIPOR2 adiponectin receptor 2 0.0238976
BPTF bromodomain PHD finger transcription factor 0.0237749
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0237045
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0236868
UBC ubiquitin C 0.0235011
TOP1 topoisomerase (DNA) I 0.023466
ACLY ATP citrate lyase 0.0234185
TP53 tumor protein p53 0.0233791
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.023343
TUBB tubulin, beta class I 0.0232921
HSF1 heat shock transcription factor 1 0.0232256
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.0232088
CD44 CD44 molecule (Indian blood group) 0.0231387
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.0230372
RPL37 ribosomal protein L37 0.0228109
CFAP44 cilia and flagella associated protein 44 0.0227694
AFTPH aftiphilin 0.0227431
CBX5 chromobox homolog 5 0.0225282
ILF3 interleukin enhancer binding factor 3, 90kDa 0.0224413
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.022173
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0221455
VGLL4 vestigial-like family member 4 0.0221256
TM9SF3 transmembrane 9 superfamily member 3 0.0220273
ZC3H14 zinc finger CCCH-type containing 14 0.0220123
S100A4 S100 calcium binding protein A4 0.0219972
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.0219344
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.0218633
MPG N-methylpurine-DNA glycosylase 0.021636
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.021609
CHN1 chimerin 1 0.0215104
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.0214791
MARCHF6 membrane associated ring-CH-type finger 6 0.0214663
CAPNS1 calpain, small subunit 1 0.0213726
NAP1L1 nucleosome assembly protein 1-like 1 0.0212688
MOSMO modulator of smoothened 0.0211967
ARRB1 arrestin, beta 1 0.0211291
DNM1L dynamin 1-like 0.0210761
CAVIN1 caveolae associated protein 1 0.021035
BCAS1 breast carcinoma amplified sequence 1 0.0208789
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0208324
FKBP4 FK506 binding protein 4, 59kDa 0.02078
USP33 ubiquitin specific peptidase 33 0.020764
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0207496
NCKAP1 NCK-associated protein 1 0.0207286
RANBP2 RAN binding protein 2 0.0206712
ANKRD28 ankyrin repeat domain 28 0.0206612
PRPF4B pre-mRNA processing factor 4B 0.0205678
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 0.0204076
SMC4 structural maintenance of chromosomes 4 0.020379
CLSTN1 calsyntenin 1 0.0203481
RPS17 ribosomal protein S17 0.0203417
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0203159
ARID1A AT rich interactive domain 1A (SWI-like) 0.0202595
MAP1B microtubule-associated protein 1B 0.0202593
CD99L2 CD99 molecule-like 2 0.0201681
KHSRP KH-type splicing regulatory protein 0.020089
BTN3A3 butyrophilin, subfamily 3, member A3 0.0199967
TPM3 tropomyosin 3 0.0198307
MRPS18B mitochondrial ribosomal protein S18B 0.019782
RHOBTB1 Rho-related BTB domain containing 1 0.0197654
RPS3 ribosomal protein S3 0.01961
RBM25 RNA binding motif protein 25 0.019553
HIPK3 homeodomain interacting protein kinase 3 0.019445
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.0194343
HMGA1 high mobility group AT-hook 1 0.0193918
H1-10 H1.10 linker histone 0.0193492
ZBTB20 zinc finger and BTB domain containing 20 0.0193246
SMAD3 SMAD family member 3 0.0191801
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.0191421
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0191111
SPRED2 sprouty-related, EVH1 domain containing 2 0.0190085
BLTP3B bridge-like lipid transfer protein family member 3B 0.018965
ZC3H13 zinc finger CCCH-type containing 13 0.0189211
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0188824
NLN neurolysin (metallopeptidase M3 family) 0.018871
KIF11 kinesin family member 11 0.0188604
MVD mevalonate (diphospho) decarboxylase 0.0188603
AGFG1 ArfGAP with FG repeats 1 0.0188409
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0188394
UBTF upstream binding transcription factor, RNA polymerase I 0.0188158
TMPO thymopoietin 0.018801
IGFBP4 insulin-like growth factor binding protein 4 0.0187712
RNFT2 ring finger protein, transmembrane 2 0.0187529
WASF2 WAS protein family, member 2 0.0187491
MFSD12 major facilitator superfamily domain containing 12 0.0186644
PBX3 pre-B-cell leukemia homeobox 3 0.0186581
GSR glutathione reductase 0.0185755
STK38 serine/threonine kinase 38 0.0185259
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0184117
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.018406
MAP7 microtubule-associated protein 7 0.0183807
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0183613
LDHB lactate dehydrogenase B 0.0183406
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0183169
EVI5 ecotropic viral integration site 5 0.01825
CEP170 centrosomal protein 170kDa 0.0182308
GNAS GNAS complex locus 0.0181846
NAMPT nicotinamide phosphoribosyltransferase 0.0181447
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0180304
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0180125
SLC38A1 solute carrier family 38, member 1 0.0180117
RPL34 ribosomal protein L34 0.0179817
FBXW4 F-box and WD repeat domain containing 4 0.0179714
MYO19 myosin XIX 0.0179607
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0179589
UBAP2 ubiquitin associated protein 2 0.0179516
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0179514
HSPH1 heat shock 105kDa/110kDa protein 1 0.0179443
NASP nuclear autoantigenic sperm protein (histone-binding) 0.0178309
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0177803
MGST1 microsomal glutathione S-transferase 1 0.0177664
RPL27A ribosomal protein L27a 0.0177506
RPS12 ribosomal protein S12 0.0177502
AURKAIP1 aurora kinase A interacting protein 1 0.0177308
CENPO centromere protein O 0.0176219
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0176005
NCAPG non-SMC condensin I complex, subunit G 0.0175727
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0175624
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.0174785
RPL18 ribosomal protein L18 0.0174221
EREG epiregulin 0.0174191
SMYD4 SET and MYND domain containing 4 0.0173745
DNM1 dynamin 1 0.0173414
PAWR PRKC, apoptosis, WT1, regulator 0.0173245
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 0.0173168
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.0172427
TNPO3 transportin 3 0.0172303
ZBTB38 zinc finger and BTB domain containing 38 0.0172133
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.0171712
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.0171153
FAM13B family with sequence similarity 13, member B 0.017037
GPS2 G protein pathway suppressor 2 0.0169994
NUDCD1 NudC domain containing 1 0.0169646
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.0169557
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0169539
MRPS5 mitochondrial ribosomal protein S5 0.0169306
HEATR1 HEAT repeat containing 1 0.0168319
ARCN1 archain 1 0.0167923
DOCK10 dedicator of cytokinesis 10 0.0166857
KIF21A kinesin family member 21A 0.0166354
RPN2 ribophorin II 0.0166265
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.0166032
RNF121 ring finger protein 121 0.0165753
SGO2 shugoshin 2 0.0165644
PRR11 proline rich 11 0.0165506
ANXA4 annexin A4 0.0165398
RNF103-CHMP3 RNF103-CHMP3 readthrough 0.0165168
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0164587
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.0164249
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.0163966
BFAR bifunctional apoptosis regulator 0.0163791
TP63 tumor protein p63 0.0163435
UGDH UDP-glucose 6-dehydrogenase 0.0163356
PANK3 pantothenate kinase 3 0.0163314
SPIRE1 spire-type actin nucleation factor 1 0.0163239
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.0162658
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0162634
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0162634
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 0.0162061
MIA2 melanoma inhibitory activity 2 0.0161852
NEMF nuclear export mediator factor 0.0161661
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0161459
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 0.0161373
NOP56 NOP56 ribonucleoprotein 0.0161166
KRT19 keratin 19, type I 0.0160945
AHCY adenosylhomocysteinase 0.0160927
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0160474
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0160427
GOLGA4 golgin A4 0.0160374
SPAG7 sperm associated antigen 7 0.0160279
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0160174
DLG5 discs, large homolog 5 (Drosophila) 0.0158893
MAGED1 melanoma antigen family D1 0.0158551
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0158253
SMOX spermine oxidase 0.0157955
STARD7 StAR-related lipid transfer (START) domain containing 7 0.0157632
PA2G4 proliferation-associated 2G4, 38kDa 0.0157584
SNX13 sorting nexin 13 0.0157576
KANSL3 KAT8 regulatory NSL complex subunit 3 0.0157469
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.0157365
SFXN5 sideroflexin 5 0.0157286
AATF apoptosis antagonizing transcription factor 0.0157171
MGLL monoglyceride lipase 0.0156985
PRTG protogenin 0.0156919
FBXL5 F-box and leucine-rich repeat protein 5 0.0156439
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.0156393
DCTN1 dynactin 1 0.015599
DTX2 deltex 2, E3 ubiquitin ligase 0.0155876
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.0155833
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.0155607
GLI2 GLI family zinc finger 2 0.0155276
KMT2A lysine (K)-specific methyltransferase 2A 0.0155053
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0154715
CCDC138 coiled-coil domain containing 138 0.0154701
DSPP dentin sialophosphoprotein 0.0154448
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0154293
SLC25A43 solute carrier family 25, member 43 0.0154199
PLK1 polo-like kinase 1 0.0154094
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0153934
SOS2 son of sevenless homolog 2 (Drosophila) 0.0153334
RBBP5 retinoblastoma binding protein 5 0.0153316
IQGAP2 IQ motif containing GTPase activating protein 2 0.0153269
TMPRSS4 transmembrane protease, serine 4 0.0153245
MTDH metadherin 0.0153221
PTK2 protein tyrosine kinase 2 0.01528
COG4 component of oligomeric golgi complex 4 0.0152244
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0151814
PRELID1 PRELI domain containing 1 0.0151589
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.015158
RPSA ribosomal protein SA 0.0151504
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0151457
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0151421
PLCH1 phospholipase C, eta 1 0.0151306
ZNF75A zinc finger protein 75a 0.0151202
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.0150571
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.0150209
FTH1 ferritin, heavy polypeptide 1 0.0149519
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.0149408
ZC3H4 zinc finger CCCH-type containing 4 0.0149348
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.0149313
GEMIN4 gem (nuclear organelle) associated protein 4 0.0149084
DCAF6 DDB1 and CUL4 associated factor 6 0.0148888
TMC7 transmembrane channel-like 7 0.0148604
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0148366
RABL6 RAB, member RAS oncogene family-like 6 0.0148007
SNX24 sorting nexin 24 0.0147877
DIAPH3 diaphanous-related formin 3 0.0147479
TM4SF20 transmembrane 4 L six family member 20 0.0147203
WNK1 WNK lysine deficient protein kinase 1 0.0147143
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0146945
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.0146911
PARK7 parkinson protein 7 0.0146448
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.0146156
RHOG ras homolog family member G 0.0146135
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.0145696
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0145672
ANLN anillin, actin binding protein 0.0145664
CEMIP2 cell migration inducing hyaluronidase 2 0.014558
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0145438
HORMAD1 HORMA domain containing 1 0.0145131
SQLE squalene epoxidase 0.014476
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.0144606
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.0144453
TPX2 TPX2, microtubule-associated 0.014426
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.014411
ZNF212 zinc finger protein 212 0.0144082
WDR75 WD repeat domain 75 0.0143528
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 0.0142761
DRC4 dynein regulatory complex subunit 4 0.0142505
ZFC3H1 zinc finger, C3H1-type containing 0.0142261
ATRAID all-trans retinoic acid-induced differentiation factor 0.0142199
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0141998
KLHL20 kelch-like family member 20 0.0141624
MAP2K1 mitogen-activated protein kinase kinase 1 0.0141375
RTN4 reticulon 4 0.0141244
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0140972
UBQLN1 ubiquilin 1 0.0140371
MAP2K6 mitogen-activated protein kinase kinase 6 0.0140135
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.0139962
BASP1 brain abundant, membrane attached signal protein 1 0.0139352
MORC4 MORC family CW-type zinc finger 4 0.0139129
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 0.0139003
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.0138951
ASXL1 additional sex combs like transcriptional regulator 1 0.013892
NRIP1 nuclear receptor interacting protein 1 0.0138877
COASY CoA synthase 0.0138816
CIP2A cellular inhibitor of PP2A 0.0138808
EEF2K eukaryotic elongation factor 2 kinase 0.0138661
GAPVD1 GTPase activating protein and VPS9 domains 1 0.0138594
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0138323
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 0.0138158
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0138093
CNTRL centriolin 0.0137983
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0137621
HSPA8 heat shock 70kDa protein 8 0.0137586
GANAB glucosidase, alpha; neutral AB 0.013676
AVEN apoptosis, caspase activation inhibitor 0.0136429
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.0136251
COLGALT1 collagen beta(1-O)galactosyltransferase 1 0.0136101
FKBP8 FK506 binding protein 8, 38kDa 0.0136014
EMC10 ER membrane protein complex subunit 10 0.0135822
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.0135447
CDC27 cell division cycle 27 0.0134962
TASP1 taspase, threonine aspartase, 1 0.0134936
ECE1 endothelin converting enzyme 1 0.0134494
MPRIP myosin phosphatase Rho interacting protein 0.0134367
AFAP1 actin filament associated protein 1 0.013424
AK1 adenylate kinase 1 0.0133679
PROCR protein C receptor, endothelial 0.01335
XXYLT1 xyloside xylosyltransferase 1 0.0133487
DARS1 aspartyl-tRNA synthetase 1 0.0133199
ATXN7L1 ataxin 7-like 1 0.0133091
CNN3 calponin 3, acidic 0.0133034
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 0.0132872
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0132726
DIS3L DIS3 like exosome 3'-5' exoribonuclease 0.0132645
GLG1 golgi glycoprotein 1 0.0132193
ADAR adenosine deaminase, RNA-specific 0.0132113
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0131921
LTN1 listerin E3 ubiquitin protein ligase 1 0.0131791
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0131547
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0131421
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.0131305
NUCB1 nucleobindin 1 0.013101
AMOTL1 angiomotin like 1 0.0130921
TRAP1 TNF receptor-associated protein 1 0.0130911
ACAD10 acyl-CoA dehydrogenase family, member 10 0.013054
RPL27 ribosomal protein L27 0.013053
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0130375
MRTFA myocardin related transcription factor A 0.0130317
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0130223
SMC1A structural maintenance of chromosomes 1A 0.0130077
YARS1 tyrosyl-tRNA synthetase 1 0.0130023
GLE1 GLE1 RNA export mediator 0.0129838
KLHL18 kelch-like family member 18 0.0129808
DPY19L3 dpy-19-like 3 (C. elegans) 0.0129801
LRRC23 leucine rich repeat containing 23 0.0129742
PTPRG protein tyrosine phosphatase, receptor type, G 0.0129604
ADAM15 ADAM metallopeptidase domain 15 0.0129546
MBD4 methyl-CpG binding domain protein 4 0.0129185
SRRM1 serine/arginine repetitive matrix 1 0.0128904
MED23 mediator complex subunit 23 0.0128903
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.0128895
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.0128552
LIMS1 LIM and senescent cell antigen-like domains 1 0.0128379
SNF8 SNF8, ESCRT-II complex subunit 0.012776
TMEM54 transmembrane protein 54 0.0127741
FBXO28 F-box protein 28 0.0127664
TMEM168 transmembrane protein 168 0.0127647
PNKP polynucleotide kinase 3'-phosphatase 0.0127555
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0127535
PLCE1 phospholipase C, epsilon 1 0.0127473
COBL cordon-bleu WH2 repeat protein 0.0127157
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0127047
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0126714
TIMP1 TIMP metallopeptidase inhibitor 1 0.0126589
VAC14 Vac14 homolog (S. cerevisiae) 0.0126377
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0126145
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0125979
HSPA1A heat shock 70kDa protein 1A 0.0125788
ARRB2 arrestin, beta 2 0.0125694
CLASP2 cytoplasmic linker associated protein 2 0.0125251
EP400 E1A binding protein p400 0.0125245
CDC42 cell division cycle 42 0.01252
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0125051
DPY19L1 dpy-19-like 1 (C. elegans) 0.0124914
WDR35 WD repeat domain 35 0.0124721
PIF1 PIF1 5'-to-3' DNA helicase 0.0124636
SLC35F6 solute carrier family 35, member F6 0.0124524
PBX1 pre-B-cell leukemia homeobox 1 0.0124316
COPS6 COP9 signalosome subunit 6 0.0124315
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0124306
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.0124252
SRGN serglycin 0.0124043
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.0124039
ZBTB7A zinc finger and BTB domain containing 7A 0.0123967
LIN28B lin-28 homolog B (C. elegans) 0.0123851
XRN2 5'-3' exoribonuclease 2 0.012382
RAN RAN, member RAS oncogene family 0.0123792
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0123769
STRBP spermatid perinuclear RNA binding protein 0.012356
PDE8B phosphodiesterase 8B 0.0123304
GRB2 growth factor receptor-bound protein 2 0.0123169
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.0123165
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0123109
EIF4E eukaryotic translation initiation factor 4E 0.0122736
LIN54 lin-54 DREAM MuvB core complex component 0.0122657
WDR4 WD repeat domain 4 0.0122535
RPL39 ribosomal protein L39 0.0122378
SDSL serine dehydratase-like 0.0122358
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.0122286
SATB2 SATB homeobox 2 0.0122213
STAG2 stromal antigen 2 0.0122196
SLC30A6 solute carrier family 30 (zinc transporter), member 6 0.0122131
AHCTF1 AT hook containing transcription factor 1 0.0121727
CCDC137 coiled-coil domain containing 137 0.0121716
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.0121373
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.0121303
ITGB4 integrin, beta 4 0.0121279
SEC63 SEC63 homolog (S. cerevisiae) 0.0121258
ENO1 enolase 1, (alpha) 0.012095
COA3 cytochrome c oxidase assembly factor 3 0.0120857
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0120713
DDRGK1 DDRGK domain containing 1 0.0120704
UBA1 ubiquitin-like modifier activating enzyme 1 0.0120504
NLRP2B NLR family pyrin domain containing 2B 0.0120437
CANT1 calcium activated nucleotidase 1 0.0120346
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.0120272
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.0120212
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) 0.0120071
KIF2A kinesin heavy chain member 2A 0.0119842
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.0119469
TMEM135 transmembrane protein 135 0.0119432
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.0119308
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0119291
METTL8 methyltransferase like 8 0.011923
TTC17 tetratricopeptide repeat domain 17 0.0119172
ZNF236 zinc finger protein 236 0.0119068
PRPF31 pre-mRNA processing factor 31 0.0119044
MRPL45 mitochondrial ribosomal protein L45 0.0119033
TFB2M transcription factor B2, mitochondrial 0.0119009
CEP164 centrosomal protein 164kDa 0.0119004
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.0118863
MMGT1 membrane magnesium transporter 1 0.011858
RBMS2 RNA binding motif, single stranded interacting protein 2 0.0118493

decreased expression

Symbol Name Standardized Value
EHBP1 EH domain binding protein 1 -0.0793715
THSD7A thrombospondin, type I, domain containing 7A -0.0780742
ARHGAP26 Rho GTPase activating protein 26 -0.0780723
PDE4D phosphodiesterase 4D, cAMP-specific -0.0753511
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0724553
MTUS1 microtubule associated tumor suppressor 1 -0.0693849
TPM4 tropomyosin 4 -0.0681728
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0677393
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0647527
HIP1 huntingtin interacting protein 1 -0.0627849
GPATCH8 G patch domain containing 8 -0.0624547
BCAS3 breast carcinoma amplified sequence 3 -0.0608818
CNTNAP3B contactin associated protein-like 3B -0.0607457
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.060371
KANK1 KN motif and ankyrin repeat domains 1 -0.0602447
FNDC3B fibronectin type III domain containing 3B -0.060194
WWOX WW domain containing oxidoreductase -0.0596198
TNS3 tensin 3 -0.0580301
TRAPPC9 trafficking protein particle complex 9 -0.0574644
FBXL20 F-box and leucine-rich repeat protein 20 -0.0557071
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0545991
BMPR1B bone morphogenetic protein receptor, type IB -0.0542095
PTPRM protein tyrosine phosphatase, receptor type, M -0.0538718
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0535823
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0533935
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0527293
TTC28 tetratricopeptide repeat domain 28 -0.0517927
PTPRJ protein tyrosine phosphatase, receptor type, J -0.0505705
AOPEP aminopeptidase O (putative) -0.0497838
PCDH9 protocadherin 9 -0.0496313
VMP1 vacuole membrane protein 1 -0.0481949
ATE1 arginyltransferase 1 -0.0480044
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0479735
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0478328
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0471645
GMDS GDP-mannose 4,6-dehydratase -0.0470006
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0469039
PDE8A phosphodiesterase 8A -0.0464046
PRKCA protein kinase C, alpha -0.0460187
ARL15 ADP-ribosylation factor-like 15 -0.0458931
MLXIP MLX interacting protein -0.0449628
THSD4 thrombospondin, type I, domain containing 4 -0.044818
OPHN1 oligophrenin 1 -0.0446545
NCOA3 nuclear receptor coactivator 3 -0.044621
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0431622
BIRC6 baculoviral IAP repeat containing 6 -0.0418496
SQSTM1 sequestosome 1 -0.0408767
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0406476
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0405912
AUTS2 autism susceptibility candidate 2 -0.0405024
FHIT fragile histidine triad -0.0403813
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0399299
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0396018
MCU mitochondrial calcium uniporter -0.0389695
APP amyloid beta (A4) precursor protein -0.0387561
SYT1 synaptotagmin I -0.0385817
GRAMD1B GRAM domain containing 1B -0.0385368
WWTR1 WW domain containing transcription regulator 1 -0.0384321
DOCK5 dedicator of cytokinesis 5 -0.038027
EXT1 exostosin glycosyltransferase 1 -0.037734
FAM107B family with sequence similarity 107, member B -0.0375575
LRMDA leucine rich melanocyte differentiation associated -0.0372164
SPAG9 sperm associated antigen 9 -0.0365139
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0363728
ENSA endosulfine alpha -0.0363037
FRMD3 FERM domain containing 3 -0.0360411
ABI2 abl-interactor 2 -0.0359923
MACROD2 MACRO domain containing 2 -0.0359438
TNRC18 trinucleotide repeat containing 18 -0.0358853
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0358033
RBPMS RNA binding protein with multiple splicing -0.0357367
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0356136
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0351019
ZNF609 zinc finger protein 609 -0.0350373
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0348731
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0347441
EXOC6B exocyst complex component 6B -0.0346824
RORA RAR-related orphan receptor A -0.0344966
MAML3 mastermind-like 3 (Drosophila) -0.0344779
MON2 MON2 homolog (S. cerevisiae) -0.0342687
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0339326
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0338982
DAPK1 death-associated protein kinase 1 -0.0338309
SRPK2 SRSF protein kinase 2 -0.033319
ALCAM activated leukocyte cell adhesion molecule -0.0330366
SLC35F3 solute carrier family 35, member F3 -0.0330116
JMJD1C jumonji domain containing 1C -0.0329454
MED13L mediator complex subunit 13-like -0.0324408
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.032352
PON2 paraoxonase 2 -0.0319724
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0318781
NF1 neurofibromin 1 -0.0318388
GDNF glial cell derived neurotrophic factor -0.0317162
LDLR low density lipoprotein receptor -0.0316578
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0316116
FMNL2 formin-like 2 -0.0316092
LAMA5 laminin, alpha 5 -0.0311907
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0311514
KDM5B lysine (K)-specific demethylase 5B -0.0311225
IARS1 isoleucyl-tRNA synthetase 1 -0.0308921
ZNF638 zinc finger protein 638 -0.0308336
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0307306
AKAP12 A kinase (PRKA) anchor protein 12 -0.0302562
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.030013
ZFAND3 zinc finger, AN1-type domain 3 -0.0299696
EP300 E1A binding protein p300 -0.029879
NRG1 neuregulin 1 -0.0297696
FNDC3A fibronectin type III domain containing 3A -0.0297133
NTN4 netrin 4 -0.0296725
MAP2K4 mitogen-activated protein kinase kinase 4 -0.0295457
LARP4 La ribonucleoprotein domain family, member 4 -0.0294817
USP3 ubiquitin specific peptidase 3 -0.0290744
ITGB5 integrin, beta 5 -0.0290652
CLDN2 claudin 2 -0.0284276
PRKCSH protein kinase C substrate 80K-H -0.0283426
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.028254
ANKRD17 ankyrin repeat domain 17 -0.0282465
PHACTR4 phosphatase and actin regulator 4 -0.0281951
YAP1 Yes-associated protein 1 -0.0281027
PSD3 pleckstrin and Sec7 domain containing 3 -0.0279709
ATXN2 ataxin 2 -0.0278533
MYO1D myosin ID -0.0277201
SERINC5 serine incorporator 5 -0.0276292
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.0275711
APTX aprataxin -0.0275657
AHI1 Abelson helper integration site 1 -0.0275018
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0273694
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 -0.0272471
MLPH melanophilin -0.0271221
PDE7B phosphodiesterase 7B -0.0270091
PLPP1 phospholipid phosphatase 1 -0.0270062
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0269886
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0269504
TMEM65 transmembrane protein 65 -0.0268401
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0267857
WWC3 WWC family member 3 -0.0267478
CLIP4 CAP-GLY domain containing linker protein family, member 4 -0.0266554
ZNF346 zinc finger protein 346 -0.0266025
JUP junction plakoglobin -0.026125
UBXN4 UBX domain protein 4 -0.0260137
SDCCAG8 serologically defined colon cancer antigen 8 -0.025957
PDLIM5 PDZ and LIM domain 5 -0.0258446
AGR2 anterior gradient 2 -0.0258101
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0257622
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0256442
NCOA2 nuclear receptor coactivator 2 -0.0255685
TNRC6A trinucleotide repeat containing 6A -0.0254905
LMNA lamin A/C -0.0254667
UBE2K ubiquitin-conjugating enzyme E2K -0.0254552
PCDHB16 protocadherin beta 16 -0.0254476
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0253884
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0253856
PCCA propionyl CoA carboxylase, alpha polypeptide -0.0252342
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0252269
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -0.0251743
HIPK2 homeodomain interacting protein kinase 2 -0.0250107
PHACTR2 phosphatase and actin regulator 2 -0.0249618
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0249565
LMBR1 limb development membrane protein 1 -0.0248701
ANAPC5 anaphase promoting complex subunit 5 -0.0248061
STK24 serine/threonine kinase 24 -0.024806
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.024789
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0246905
CAMKMT calmodulin-lysine N-methyltransferase -0.024613
PER2 period circadian clock 2 -0.0245147
DNM2 dynamin 2 -0.0244319
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0243964
GPHN gephyrin -0.024352
MED13 mediator complex subunit 13 -0.0243133
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0240728
TBC1D5 TBC1 domain family, member 5 -0.0239177
TAOK3 TAO kinase 3 -0.0238973
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0238769
RB1CC1 RB1-inducible coiled-coil 1 -0.0237633
OGA O-GlcNAcase -0.0237533
SHLD2 shieldin complex subunit 2 -0.023657
ZNF652 zinc finger protein 652 -0.0236101
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0235609
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0234792
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 -0.0234791
PAQR5 progestin and adipoQ receptor family member V -0.0233185
IGSF1 immunoglobulin superfamily, member 1 -0.0233107
RAD51B RAD51 paralog B -0.0233072
ATAD2B ATPase family, AAA domain containing 2B -0.0232691
ARHGAP5 Rho GTPase activating protein 5 -0.0232583
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0231866
CHPT1 choline phosphotransferase 1 -0.0231213
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -0.0230599
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0230214
TXNRD1 thioredoxin reductase 1 -0.0230111
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0229563
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0229442
CDK13 cyclin-dependent kinase 13 -0.0228824
PTGR1 prostaglandin reductase 1 -0.0228616
CTSD cathepsin D -0.022831
LRP6 low density lipoprotein receptor-related protein 6 -0.0228257
SYAP1 synapse associated protein 1 -0.0227194
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0226016
POC1B POC1 centriolar protein B -0.0225223
FCGBP Fc fragment of IgG binding protein -0.0224758
FGG fibrinogen gamma chain -0.0223928
DNAH14 dynein, axonemal, heavy chain 14 -0.0223725
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0223311
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -0.0222744
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.0222519
GRAMD1A GRAM domain containing 1A -0.0222122
METAP2 methionyl aminopeptidase 2 -0.0221383
PYGB phosphorylase, glycogen; brain -0.0220889
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.021983
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0219616
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0219346
RSF1 remodeling and spacing factor 1 -0.0219328
AKAP11 A kinase (PRKA) anchor protein 11 -0.0218546
NRP1 neuropilin 1 -0.0217764
CLINT1 clathrin interactor 1 -0.0215808
STAT2 signal transducer and activator of transcription 2, 113kDa -0.0215579
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.021553
CCDC91 coiled-coil domain containing 91 -0.0214577
SBF2 SET binding factor 2 -0.0214432
GIPC1 GIPC PDZ domain containing family, member 1 -0.0213694
KIAA1549 KIAA1549 -0.0212753
FNBP4 formin binding protein 4 -0.0212389
SCARB1 scavenger receptor class B, member 1 -0.0212311
PTER phosphotriesterase related -0.0212308
R3HDM2 R3H domain containing 2 -0.0211081
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.0210776
PPARG peroxisome proliferator-activated receptor gamma -0.0208641
COG5 component of oligomeric golgi complex 5 -0.0208543
PICALM phosphatidylinositol binding clathrin assembly protein -0.0207797
THRB thyroid hormone receptor, beta -0.0207534
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0206922
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0206893
TBL1X transducin (beta)-like 1X-linked -0.0206076
ACTN1 actinin, alpha 1 -0.0205533
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0205205
RPS6 ribosomal protein S6 -0.0204264
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0203903
SCAF11 SR-related CTD-associated factor 11 -0.0203792
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.0203422
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -0.0203264
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0202088
URI1 URI1, prefoldin-like chaperone -0.0201976
CNKSR3 CNKSR family member 3 -0.0201857
OSBPL10 oxysterol binding protein-like 10 -0.0201783
CST1 cystatin SN -0.0201204
RPS8 ribosomal protein S8 -0.0200993
FAM168B family with sequence similarity 168, member B -0.0200518
MTFR1 mitochondrial fission regulator 1 -0.0200334
TMEM156 transmembrane protein 156 -0.0199832
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0199618
PM20D1 peptidase M20 domain containing 1 -0.0199122
DAND5 DAN domain family member 5, BMP antagonist -0.0199104
LPP LIM domain containing preferred translocation partner in lipoma -0.019722
FBXO11 F-box protein 11 -0.0197047
PNISR PNN-interacting serine/arginine-rich protein -0.0197023
ARHGAP18 Rho GTPase activating protein 18 -0.0196931
IGF1R insulin-like growth factor 1 receptor -0.0195427
INVS inversin -0.0195125
OLA1 Obg-like ATPase 1 -0.0194845
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0194814
H2AZ2 H2A.Z variant histone 2 -0.0194544
NAT8 N-acetyltransferase 8 (GCN5-related, putative) -0.0193689
CLIP2 CAP-GLY domain containing linker protein 2 -0.0192904
SOS1 son of sevenless homolog 1 (Drosophila) -0.0192765
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0192752
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0192127
EZR ezrin -0.0192118
VCL vinculin -0.0191792
SUGP2 SURP and G patch domain containing 2 -0.0191142
ZNF106 zinc finger protein 106 -0.0190686
INSR insulin receptor -0.0190266
IP6K2 inositol hexakisphosphate kinase 2 -0.0189726
ZNF148 zinc finger protein 148 -0.0189507
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 -0.0189191
PUM1 pumilio RNA-binding family member 1 -0.0188638
PHIP pleckstrin homology domain interacting protein -0.0188129
USP25 ubiquitin specific peptidase 25 -0.0187958
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0187635
DUSP4 dual specificity phosphatase 4 -0.0187207
HELZ helicase with zinc finger -0.0186674
SH3RF1 SH3 domain containing ring finger 1 -0.0186329
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0186132
KCMF1 potassium channel modulatory factor 1 -0.0186088
CHD1L chromodomain helicase DNA binding protein 1-like -0.0185708
TSC22D1 TSC22 domain family, member 1 -0.0185558
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.0185502
MEGF9 multiple EGF-like-domains 9 -0.0185228
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0185162
USP36 ubiquitin specific peptidase 36 -0.018492
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -0.0184863
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0184476
TSPAN14 tetraspanin 14 -0.0184219
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0184071
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0183757
USP9X ubiquitin specific peptidase 9, X-linked -0.01837
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.018342
PCED1B PC-esterase domain containing 1B -0.018328
ATRN attractin -0.0182263
USP48 ubiquitin specific peptidase 48 -0.0182131
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0182069
MAPK8 mitogen-activated protein kinase 8 -0.0181186
PKN1 protein kinase N1 -0.0181103
KANTR KDM5C adjacent non-coding transcript -0.018085
PLD3 phospholipase D family, member 3 -0.0180845
SYNRG synergin, gamma -0.0180306
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0180264
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.018026
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0179967
MTCL1 microtubule crosslinking factor 1 -0.0179398
ACBD3 acyl-CoA binding domain containing 3 -0.0178791
CPNE8 copine VIII -0.0178776
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.0178001
EVL Enah/Vasp-like -0.0177582
NUDCD3 NudC domain containing 3 -0.0177539
PDIA5 protein disulfide isomerase family A, member 5 -0.017727
PALLD palladin, cytoskeletal associated protein -0.0176865
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0176849
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -0.0176722
ARHGAP1 Rho GTPase activating protein 1 -0.0176648
CYSTM1 cysteine-rich transmembrane module containing 1 -0.0176623
HOMER2 homer scaffolding protein 2 -0.0176589
SH3D19 SH3 domain containing 19 -0.0176247
NUMB numb homolog (Drosophila) -0.0176189
GOLGB1 golgin B1 -0.0175906
WAC WW domain containing adaptor with coiled-coil -0.0175384
PATJ PATJ crumbs cell polarity complex component -0.0175126
TRAF3 TNF receptor-associated factor 3 -0.0174706
TUBA1C tubulin, alpha 1c -0.0174475
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) -0.0174056
CCDC146 coiled-coil domain containing 146 -0.0173915
RBBP4 retinoblastoma binding protein 4 -0.0173534
TENT4B terminal nucleotidyltransferase 4B -0.0173475
TM4SF1 transmembrane 4 L six family member 1 -0.0173148
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0173016
REEP5 receptor accessory protein 5 -0.0172853
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.0172655
MIPOL1 mirror-image polydactyly 1 -0.0172654
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -0.0172551
GDF15 growth differentiation factor 15 -0.0171883
CUL5 cullin 5 -0.0171751
DOCK4 dedicator of cytokinesis 4 -0.0171678
KCTD20 potassium channel tetramerization domain containing 20 -0.0171496
NFX1 nuclear transcription factor, X-box binding 1 -0.017145
GSE1 Gse1 coiled-coil protein -0.0171167
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.017013
ANXA7 annexin A7 -0.0170064
CDHR3 cadherin-related family member 3 -0.0170005
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -0.0169691
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0169084
PARD3B par-3 family cell polarity regulator beta -0.016892
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0168826
IMMT inner membrane protein, mitochondrial -0.0168727
KDM3B lysine (K)-specific demethylase 3B -0.016758
NEK7 NIMA-related kinase 7 -0.0167508
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -0.016741
MTCH2 mitochondrial carrier 2 -0.016714
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.0167056
MAST4 microtubule associated serine/threonine kinase family member 4 -0.016703
GORASP2 golgi reassembly stacking protein 2, 55kDa -0.0166823
CEP112 centrosomal protein 112kDa -0.0166735
BCL2L1 BCL2-like 1 -0.0166697
FRMD5 FERM domain containing 5 -0.016663
DIAPH2 diaphanous-related formin 2 -0.0166404
ELOB elongin B -0.0165998
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0165752
AGO3 argonaute RISC catalytic component 3 -0.0165668
LUC7L LUC7-like (S. cerevisiae) -0.0165482
DOCK1 dedicator of cytokinesis 1 -0.0165233
TMEM39A transmembrane protein 39A -0.0165229
RSBN1L round spermatid basic protein 1-like -0.0165171
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0165169
L2HGDH L-2-hydroxyglutarate dehydrogenase -0.0164886
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -0.0164465
ZNF644 zinc finger protein 644 -0.0164332
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0164284
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -0.0163771
REV1 REV1, polymerase (DNA directed) -0.0163759
RIC8B RIC8 guanine nucleotide exchange factor B -0.0163326
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -0.0163321
CNTN1 contactin 1 -0.016318
N4BP2 NEDD4 binding protein 2 -0.016236
TLE5 TLE family member 5, transcriptional modulator -0.0162258
EXOC4 exocyst complex component 4 -0.0162074
RIN2 Ras and Rab interactor 2 -0.0161546
BLVRB biliverdin reductase B -0.0161541
PLAUR plasminogen activator, urokinase receptor -0.0161058
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0161022
LASP1 LIM and SH3 protein 1 -0.0161011
PTPRK protein tyrosine phosphatase, receptor type, K -0.0160997
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -0.0160948
TRIO trio Rho guanine nucleotide exchange factor -0.0160635
ABLIM1 actin binding LIM protein 1 -0.0160453
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0160403
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0160338
MCTP1 multiple C2 domains, transmembrane 1 -0.0160189
NRDE2 NRDE-2, necessary for RNA interference, domain containing -0.015952
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -0.0159402
KMT2E lysine (K)-specific methyltransferase 2E -0.0159173
UVRAG UV radiation resistance associated -0.0158938
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0158846
PRPF8 pre-mRNA processing factor 8 -0.0158823
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0158617
CENPP centromere protein P -0.0158534
LRRK1 leucine-rich repeat kinase 1 -0.0158437
GOLPH3L golgi phosphoprotein 3-like -0.0158397
SLC22A23 solute carrier family 22, member 23 -0.0158338
UBN2 ubinuclein 2 -0.0157822
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.0157814
SMAD2 SMAD family member 2 -0.0157572
RPS5 ribosomal protein S5 -0.0157196
PUM2 pumilio RNA-binding family member 2 -0.0157143
MYO5C myosin VC -0.0157128
FOXK2 forkhead box K2 -0.0157002
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.0156926
GPR107 G protein-coupled receptor 107 -0.0156599
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.0156397
OSGIN2 oxidative stress induced growth inhibitor family member 2 -0.0156375
PTBP3 polypyrimidine tract binding protein 3 -0.0156166
ARHGAP11B Rho GTPase activating protein 11B -0.0156046
RAB6A RAB6A, member RAS oncogene family -0.0155888
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.0155748
BABAM2 BRISC and BRCA1 A complex member 2 -0.0155094
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.0154507
FAF1 Fas (TNFRSF6) associated factor 1 -0.0153989
FANCI Fanconi anemia, complementation group I -0.0153981
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0153501
NBEAL1 neurobeachin-like 1 -0.0153495
ZNF292 zinc finger protein 292 -0.0153372
TNPO1 transportin 1 -0.0153025
TOM1L2 target of myb1-like 2 (chicken) -0.0153004
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -0.015216
FAM193A family with sequence similarity 193, member A -0.0151284
NCOA7 nuclear receptor coactivator 7 -0.0150964
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0150903
DNMBP dynamin binding protein -0.0150877
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.0150396
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 -0.0150059
DTNB dystrobrevin, beta -0.0150011
HDAC8 histone deacetylase 8 -0.0149844
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.0149587
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.0149334
TSC22D2 TSC22 domain family, member 2 -0.014929
RPL23A ribosomal protein L23a -0.0149151
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.0149091
TMX4 thioredoxin-related transmembrane protein 4 -0.0148955
EXOC6 exocyst complex component 6 -0.0148782
SIRT1 sirtuin 1 -0.0148766
DIAPH1 diaphanous-related formin 1 -0.0148671
PRKD2 protein kinase D2 -0.014828
RNF115 ring finger protein 115 -0.0148214
NOL10 nucleolar protein 10 -0.0148168
ZMYM2 zinc finger, MYM-type 2 -0.0147906
RIOK3 RIO kinase 3 -0.0147729
PRICKLE2 prickle homolog 2 (Drosophila) -0.0147596
EEIG1 estrogen-induced osteoclastogenesis regulator 1 -0.0147568
KIAA0319L KIAA0319-like -0.0147554
PTOV1 prostate tumor overexpressed 1 -0.0147498
KIAA2026 KIAA2026 -0.0147412
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0147374
GLIS3 GLIS family zinc finger 3 -0.0147347
TYK2 tyrosine kinase 2 -0.0147159
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0147148
CYRIB CYFIP related Rac1 interactor B -0.0146448
SMOC1 SPARC related modular calcium binding 1 -0.0146395
POFUT3 protein O-fucosyltransferase 3 -0.0146157
HEATR5B HEAT repeat containing 5B -0.0146139
EML4 echinoderm microtubule associated protein like 4 -0.0145965
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.01459
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0145715
HEATR5A HEAT repeat containing 5A -0.0145507
ACVR1 activin A receptor, type I -0.0145286
HAVCR1 hepatitis A virus cellular receptor 1 -0.0145258
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0145123
KLHDC10 kelch domain containing 10 -0.0144917
RHOT1 ras homolog family member T1 -0.0144771
INO80E INO80 complex subunit E -0.0144685
SHLD1 shieldin complex subunit 1 -0.0144618
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0144435
LPAR1 lysophosphatidic acid receptor 1 -0.0144312
UBE2H ubiquitin-conjugating enzyme E2H -0.014424
DENND4C DENN/MADD domain containing 4C -0.0144127
MASTL microtubule associated serine/threonine kinase-like -0.0143847
LRP11 low density lipoprotein receptor-related protein 11 -0.0143584
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0143437
USP15 ubiquitin specific peptidase 15 -0.0143116
RPL13A ribosomal protein L13a -0.0142966
ATXN1 ataxin 1 -0.0142748
SMG7 SMG7 nonsense mediated mRNA decay factor -0.0142685
ZNF331 zinc finger protein 331 -0.0142631
FUS FUS RNA binding protein -0.014255
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.014232
IGFBP3 insulin-like growth factor binding protein 3 -0.0141942
COL4A5 collagen, type IV, alpha 5 -0.0141898
ARHGAP12 Rho GTPase activating protein 12 -0.014173
FKBP10 FK506 binding protein 10, 65 kDa -0.0141667
XPO1 exportin 1 -0.0141492
TAOK1 TAO kinase 1 -0.0141143
BBX bobby sox homolog (Drosophila) -0.0141092
KMT2C lysine (K)-specific methyltransferase 2C -0.0140927
TCF25 transcription factor 25 (basic helix-loop-helix) -0.0140762