A549_NVP-BSK805 2HCl_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description NVP-BSK805 2HCl 100nM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_NVP-BSK805 2HCl_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.242424
FTL ferritin, light polypeptide 0.0980025
KRT8 keratin 8, type II 0.0842305
ENO1 enolase 1, (alpha) 0.0835229
RAB10 RAB10, member RAS oncogene family 0.077353
AGR2 anterior gradient 2 0.0682086
PKM pyruvate kinase, muscle 0.0656599
MUSK muscle, skeletal, receptor tyrosine kinase 0.063315
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0631651
AKR1C3 aldo-keto reductase family 1, member C3 0.0616655
RPLP2 ribosomal protein, large, P2 0.0601576
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0566708
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0546397
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0543352
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0540147
TKT transketolase 0.0525813
RNF213 ring finger protein 213 0.0517168
ACTN4 actinin, alpha 4 0.0513429
KRT18 keratin 18, type I 0.0491462
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.048667
IGSF11 immunoglobulin superfamily, member 11 0.046344
MYOF myoferlin 0.0455802
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0451979
BICD1 bicaudal D homolog 1 (Drosophila) 0.0439678
TUBB tubulin, beta class I 0.0430579
FTH1 ferritin, heavy polypeptide 1 0.0418311
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0404141
TPX2 TPX2, microtubule-associated 0.0402248
TM4SF1 transmembrane 4 L six family member 1 0.0395301
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0395197
CMIP c-Maf inducing protein 0.0386172
DST dystonin 0.0381228
UBL4A ubiquitin-like 4A 0.0380644
FLNA filamin A, alpha 0.0379684
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0377363
DOCK5 dedicator of cytokinesis 5 0.0376876
NRP1 neuropilin 1 0.037448
ACLY ATP citrate lyase 0.0360972
PCNX2 pecanex 2 0.0358031
DSG2 desmoglein 2 0.0357607
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0356357
ANXA1 annexin A1 0.0355825
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0353293
MRTFA myocardin related transcription factor A 0.0350968
EXOC4 exocyst complex component 4 0.0349636
KPNB1 karyopherin (importin) beta 1 0.0348294
FADS2 fatty acid desaturase 2 0.0346066
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0345506
TBC1D5 TBC1 domain family, member 5 0.0342635
HSPG2 heparan sulfate proteoglycan 2 0.034054
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0335704
NQO1 NAD(P)H dehydrogenase, quinone 1 0.0334489
USP37 ubiquitin specific peptidase 37 0.0332548
MAP1B microtubule-associated protein 1B 0.033124
CENPF centromere protein F, 350/400kDa 0.0324593
WWC1 WW and C2 domain containing 1 0.0323764
PTPRA protein tyrosine phosphatase, receptor type, A 0.0322863
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0320509
RPS5 ribosomal protein S5 0.031711
ITGA6 integrin, alpha 6 0.0312124
FLNB filamin B, beta 0.0310062
LARP1 La ribonucleoprotein domain family, member 1 0.0309214
BRI3BP BRI3 binding protein 0.03066
NFX1 nuclear transcription factor, X-box binding 1 0.030535
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0304527
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0303579
CTCF CCCTC-binding factor (zinc finger protein) 0.0303499
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0302339
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.0301527
ZNF609 zinc finger protein 609 0.029919
CANX calnexin 0.0296002
PHKB phosphorylase kinase, beta 0.0295023
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0294766
CLTC clathrin, heavy chain (Hc) 0.0293432
NT5C2 5'-nucleotidase, cytosolic II 0.0291828
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0289802
KDM5A lysine (K)-specific demethylase 5A 0.0289267
RPL37A ribosomal protein L37a 0.0287962
KIF5B kinesin family member 5B 0.0284686
SMYD3 SET and MYND domain containing 3 0.0280686
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0280644
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.0278113
WNT7B wingless-type MMTV integration site family, member 7B 0.0277907
NRCAM neuronal cell adhesion molecule 0.027476
VGLL4 vestigial-like family member 4 0.0272467
SRRM2 serine/arginine repetitive matrix 2 0.0272233
PA2G4 proliferation-associated 2G4, 38kDa 0.0271576
SON SON DNA binding protein 0.0270434
PRC1 protein regulator of cytokinesis 1 0.026859
RDX radixin 0.0268523
BSG basigin (Ok blood group) 0.0267552
SETD2 SET domain containing 2 0.0267323
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.0264806
LGSN lengsin, lens protein with glutamine synthetase domain 0.0263469
RPS16 ribosomal protein S16 0.0263039
BRCA1 breast cancer 1, early onset 0.0263001
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0262436
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.0261147
RPS17 ribosomal protein S17 0.0257602
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0256314
MAP2K5 mitogen-activated protein kinase kinase 5 0.0256148
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.02556
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.0252134
FAT1 FAT atypical cadherin 1 0.0251618
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.0250383
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0249381
SEPTIN7 septin 7 0.0249234
KIF14 kinesin family member 14 0.0247304
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0244635
ITGB5 integrin, beta 5 0.0244396
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.0244173
MFSD12 major facilitator superfamily domain containing 12 0.0243617
BLTP1 bridge-like lipid transfer protein family member 1 0.0241997
FANCA Fanconi anemia, complementation group A 0.0241731
ZNRF3 zinc and ring finger 3 0.0239675
H3-3B H3.3 histone B 0.0239124
P4HB prolyl 4-hydroxylase, beta polypeptide 0.023831
KIF11 kinesin family member 11 0.0237486
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0236706
RUFY2 RUN and FYVE domain containing 2 0.0234716
MAP2K1 mitogen-activated protein kinase kinase 1 0.0232592
BICC1 BicC family RNA binding protein 1 0.0232537
MARCHF7 membrane associated ring-CH-type finger 7 0.0231607
PKN2 protein kinase N2 0.0230959
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.023077
IPMK inositol polyphosphate multikinase 0.0230155
MYADM myeloid-associated differentiation marker 0.0229981
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0229586
LCLAT1 lysocardiolipin acyltransferase 1 0.022947
NT5C 5', 3'-nucleotidase, cytosolic 0.0229126
PCLAF PCNA clamp associated factor 0.0228298
CD63 CD63 molecule 0.0228278
RACK1 receptor for activated C kinase 1 0.0227983
EEF2 eukaryotic translation elongation factor 2 0.0227438
NACA nascent polypeptide-associated complex alpha subunit 0.0226158
PCDH9 protocadherin 9 0.0224168
SEC11A SEC11 homolog A (S. cerevisiae) 0.0222614
MDN1 MDN1, midasin homolog (yeast) 0.0221175
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0220537
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0220397
MGST1 microsomal glutathione S-transferase 1 0.0220356
TFPI2 tissue factor pathway inhibitor 2 0.0220263
DCLK2 doublecortin-like kinase 2 0.0220207
COPA coatomer protein complex, subunit alpha 0.0219353
CDK6 cyclin-dependent kinase 6 0.0219002
XPO1 exportin 1 0.0218238
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.02182
RNF111 ring finger protein 111 0.021812
SFT2D2 SFT2 domain containing 2 0.0217704
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.0215384
TM4SF20 transmembrane 4 L six family member 20 0.0214596
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.021301
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0212153
TMEM120B transmembrane protein 120B 0.0211477
APTX aprataxin 0.0211301
NRIP1 nuclear receptor interacting protein 1 0.0209752
GAB2 GRB2-associated binding protein 2 0.0209723
MKI67 marker of proliferation Ki-67 0.0208996
S100A10 S100 calcium binding protein A10 0.0208227
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0206906
ECT2 epithelial cell transforming 2 0.0206809
HSPA8 heat shock 70kDa protein 8 0.0205578
SACS sacsin molecular chaperone 0.0205294
EBF1 early B-cell factor 1 0.0204155
SIK3 SIK family kinase 3 0.0203938
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0203525
PDLIM5 PDZ and LIM domain 5 0.0203338
ERRFI1 ERBB receptor feedback inhibitor 1 0.0202963
STIL SCL/TAL1 interrupting locus 0.0202922
BRWD3 bromodomain and WD repeat domain containing 3 0.0202795
RAB21 RAB21, member RAS oncogene family 0.0201919
WAPL WAPL cohesin release factor 0.0201525
ARHGAP12 Rho GTPase activating protein 12 0.0201457
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.0201447
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0201446
MMS22L MMS22-like, DNA repair protein 0.0201378
KIAA1671 KIAA1671 0.0200777
DCP1A decapping mRNA 1A 0.0200677
NPAS2 neuronal PAS domain protein 2 0.0200225
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0200197
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.0199656
CCDC88A coiled-coil domain containing 88A 0.0199607
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 0.019938
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.0198977
FNBP4 formin binding protein 4 0.0198784
MAGT1 magnesium transporter 1 0.0198766
DNM2 dynamin 2 0.0198277
USP8 ubiquitin specific peptidase 8 0.0198267
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0196513
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0195817
KIFC3 kinesin family member C3 0.0195573
DMXL2 Dmx-like 2 0.0195357
KMT2C lysine (K)-specific methyltransferase 2C 0.0195259
MCM4 minichromosome maintenance complex component 4 0.0195094
BICD2 bicaudal D homolog 2 (Drosophila) 0.0194481
YEATS2 YEATS domain containing 2 0.0193906
COP1 COP1 E3 ubiquitin ligase 0.0193776
KLHDC10 kelch domain containing 10 0.0193571
CENPB centromere protein B, 80kDa 0.0193377
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.0193152
SRFBP1 serum response factor binding protein 1 0.0192618
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.0192523
PRDX1 peroxiredoxin 1 0.0192303
KRT81 keratin 81, type II 0.0191905
FANCI Fanconi anemia, complementation group I 0.0191877
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0191802
RPL29 ribosomal protein L29 0.0190997
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0190769
KYAT1 kynurenine aminotransferase 1 0.0190265
RHOA ras homolog family member A 0.0189809
ZBTB38 zinc finger and BTB domain containing 38 0.0189746
IGF1R insulin-like growth factor 1 receptor 0.0189038
ATAD5 ATPase family, AAA domain containing 5 0.0188778
BTN3A3 butyrophilin, subfamily 3, member A3 0.018869
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.0188308
MICU1 mitochondrial calcium uptake 1 0.0187953
HPCAL1 hippocalcin-like 1 0.0187675
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0187522
CBX5 chromobox homolog 5 0.0187345
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0186995
HELLS helicase, lymphoid-specific 0.0186343
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0186209
FKBP4 FK506 binding protein 4, 59kDa 0.0185925
RPL39 ribosomal protein L39 0.018571
PCM1 pericentriolar material 1 0.0185428
RPL12 ribosomal protein L12 0.0184426
KIAA0232 KIAA0232 0.0184352
GUSB glucuronidase, beta 0.0184223
CCND1 cyclin D1 0.0183993
ENOSF1 enolase superfamily member 1 0.0183295
ACOT7 acyl-CoA thioesterase 7 0.0182064
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.0181944
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0181309
AEBP2 AE binding protein 2 0.0181093
SQLE squalene epoxidase 0.018021
LDAH lipid droplet associated hydrolase 0.017959
RAD51B RAD51 paralog B 0.017956
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0179314
MEIS2 Meis homeobox 2 0.0179286
PITPNA phosphatidylinositol transfer protein, alpha 0.0178159
RHOBTB1 Rho-related BTB domain containing 1 0.0177739
FGL1 fibrinogen-like 1 0.0177098
PRNP prion protein 0.0176906
ARMH3 armadillo like helical domain containing 3 0.0176877
CORO1C coronin, actin binding protein, 1C 0.0176839
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0176828
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.0176402
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0176368
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0175239
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 0.0175209
KRT19 keratin 19, type I 0.0175202
MTPN myotrophin 0.0174966
LACTB2 lactamase, beta 2 0.0174942
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.0174607
EPHB4 EPH receptor B4 0.0174529
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0173419
WWTR1 WW domain containing transcription regulator 1 0.0173331
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.017301
NAMPT nicotinamide phosphoribosyltransferase 0.0172952
PRKD1 protein kinase D1 0.0172722
PHTF2 putative homeodomain transcription factor 2 0.0172078
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0171755
KIF13A kinesin family member 13A 0.0170906
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.0170881
GATAD2B GATA zinc finger domain containing 2B 0.017088
TP53I3 tumor protein p53 inducible protein 3 0.0170289
SOCS4 suppressor of cytokine signaling 4 0.0170193
SMIM29 small integral membrane protein 29 0.0170103
CAPNS1 calpain, small subunit 1 0.0169969
RPS8 ribosomal protein S8 0.0169594
BCR breakpoint cluster region 0.0169532
FBXL20 F-box and leucine-rich repeat protein 20 0.0169489
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0168839
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0167919
UNC93B1 unc-93 homolog B1 (C. elegans) 0.0167703
BRWD1 bromodomain and WD repeat domain containing 1 0.0167614
MASTL microtubule associated serine/threonine kinase-like 0.0167325
SANBR SANT and BTB domain regulator of CSR 0.0167275
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.0167146
HMG20A high mobility group 20A 0.0166477
CD151 CD151 molecule (Raph blood group) 0.0166365
RPLP0 ribosomal protein, large, P0 0.0166112
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.0166104
WDR62 WD repeat domain 62 0.0166102
ANLN anillin, actin binding protein 0.016548
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.0164786
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 0.0164727
MRPS18B mitochondrial ribosomal protein S18B 0.0164623
SHLD2 shieldin complex subunit 2 0.0164141
CLASP2 cytoplasmic linker associated protein 2 0.0163412
CLIC1 chloride intracellular channel 1 0.0163253
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0162496
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0162477
RPL19 ribosomal protein L19 0.0162243
ADAM10 ADAM metallopeptidase domain 10 0.0162064
YBX1 Y box binding protein 1 0.0161887
SMG5 SMG5 nonsense mediated mRNA decay factor 0.0161755
AHCTF1 AT hook containing transcription factor 1 0.0161719
BBX bobby sox homolog (Drosophila) 0.016149
RPL4 ribosomal protein L4 0.0161297
CDCA2 cell division cycle associated 2 0.0161058
NKTR natural killer cell triggering receptor 0.016078
RHOF ras homolog family member F (in filopodia) 0.0160543
ZFAND5 zinc finger, AN1-type domain 5 0.0160458
NOMO1 NODAL modulator 1 0.0160402
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.0160288
DIS3L DIS3 like exosome 3'-5' exoribonuclease 0.0159881
KIRREL3 kin of IRRE like 3 (Drosophila) 0.0159641
ATL3 atlastin GTPase 3 0.015959
RPN1 ribophorin I 0.0159447
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0159319
RAP1GAP RAP1 GTPase activating protein 0.0159305
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0159177
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.0159145
AHCY adenosylhomocysteinase 0.015902
SLPI secretory leukocyte peptidase inhibitor 0.0158949
PDLIM1 PDZ and LIM domain 1 0.0158391
MZT2B mitotic spindle organizing protein 2B 0.0158284
STAT5B signal transducer and activator of transcription 5B 0.0158214
RPS23 ribosomal protein S23 0.0157921
SURF4 surfeit 4 0.0157848
TOR1AIP2 torsin A interacting protein 2 0.015765
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0157531
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.015745
BMAL2 basic helix-loop-helix ARNT like 2 0.0157414
IGF2R insulin-like growth factor 2 receptor 0.0157221
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 0.0157162
ANKIB1 ankyrin repeat and IBR domain containing 1 0.015708
IQCB1 IQ motif containing B1 0.0156754
PDE7A phosphodiesterase 7A 0.0156539
GRK5 G protein-coupled receptor kinase 5 0.0156392
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.0156392
UTP4 UTP4 small subunit processome component 0.0155957
PRKCE protein kinase C, epsilon 0.0155921
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.0155908
CD109 CD109 molecule 0.0155808
MYLK myosin light chain kinase 0.0155736
RSRC2 arginine/serine-rich coiled-coil 2 0.0155632
RAN RAN, member RAS oncogene family 0.015515
COA7 cytochrome c oxidase assembly factor 7 (putative) 0.015505
ZC3H7A zinc finger CCCH-type containing 7A 0.0155025
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.0154661
NCAPG2 non-SMC condensin II complex, subunit G2 0.0154214
RTN3 reticulon 3 0.0154118
SEC13 SEC13 homolog (S. cerevisiae) 0.0154048
GPATCH2 G patch domain containing 2 0.01539
TMX3 thioredoxin-related transmembrane protein 3 0.0153836
TXN2 thioredoxin 2 0.0153596
RPL37 ribosomal protein L37 0.0153582
EVI5 ecotropic viral integration site 5 0.0153347
MARK2 MAP/microtubule affinity-regulating kinase 2 0.0153304
LONP1 lon peptidase 1, mitochondrial 0.0152392
ADCY9 adenylate cyclase 9 0.0152377
PDIA3 protein disulfide isomerase family A, member 3 0.0152183
ITCH itchy E3 ubiquitin protein ligase 0.0151509
NHP2 NHP2 ribonucleoprotein 0.0151163
ZFP36L2 ZFP36 ring finger protein-like 2 0.0151106
IST1 increased sodium tolerance 1 homolog (yeast) 0.0151013
CA12 carbonic anhydrase XII 0.0150944
FBXO16 F-box protein 16 0.0150782
S100A6 S100 calcium binding protein A6 0.0150539
INTS2 integrator complex subunit 2 0.0150245
NRBP1 nuclear receptor binding protein 1 0.0150211
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.0150205
MRPL12 mitochondrial ribosomal protein L12 0.0150128
ZYG11B zyg-11 family member B, cell cycle regulator 0.0149981
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 0.0149911
BBS4 Bardet-Biedl syndrome 4 0.0149252
ARHGAP42 Rho GTPase activating protein 42 0.0149217
SMAD5 SMAD family member 5 0.0149216
UHMK1 U2AF homology motif (UHM) kinase 1 0.0149202
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.014911
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.0149074
RPTOR regulatory associated protein of MTOR, complex 1 0.0148892
LETMD1 LETM1 domain containing 1 0.0148848
RANBP2 RAN binding protein 2 0.0148813
FAM193A family with sequence similarity 193, member A 0.0148742
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 0.0148622
CABIN1 calcineurin binding protein 1 0.0148461
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.0148084
LUZP1 leucine zipper protein 1 0.0148002
RC3H2 ring finger and CCCH-type domains 2 0.0147792
TDRD3 tudor domain containing 3 0.014754
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.0147439
RPS21 ribosomal protein S21 0.0147428
WASF2 WAS protein family, member 2 0.0147132
NEBL nebulette 0.0147129
FOXRED2 FAD-dependent oxidoreductase domain containing 2 0.0147023
RPS2 ribosomal protein S2 0.0147022
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 0.0146788
DERL2 derlin 2 0.0145989
PRMT3 protein arginine methyltransferase 3 0.0145756
PHGDH phosphoglycerate dehydrogenase 0.0145557
OSBPL9 oxysterol binding protein-like 9 0.0145422
TCERG1 transcription elongation regulator 1 0.0145268
ATP11C ATPase, class VI, type 11C 0.0145141
PDIA4 protein disulfide isomerase family A, member 4 0.0144973
RSL24D1 ribosomal L24 domain containing 1 0.0144849
RPS29 ribosomal protein S29 0.0144826
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0144424
ABHD17B abhydrolase domain containing 17B 0.0144347
STMP1 short transmembrane mitochondrial protein 1 0.0144215
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.0144153
FKBP3 FK506 binding protein 3, 25kDa 0.0143901
ZMYM5 zinc finger, MYM-type 5 0.0143811
NUSAP1 nucleolar and spindle associated protein 1 0.0143545
CCDC34 coiled-coil domain containing 34 0.0143192
DENND1A DENN/MADD domain containing 1A 0.0143083
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0142993
RPL10A ribosomal protein L10a 0.0142642
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.0142535
NUP88 nucleoporin 88kDa 0.0142396
XPC xeroderma pigmentosum, complementation group C 0.014239
UIMC1 ubiquitin interaction motif containing 1 0.0142134
LSM12 LSM12 homolog (S. cerevisiae) 0.0142049
FNDC3A fibronectin type III domain containing 3A 0.014187
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.0141806
RSL1D1 ribosomal L1 domain containing 1 0.0141784
CREB1 cAMP responsive element binding protein 1 0.0141273
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.0141207
CAPRIN1 cell cycle associated protein 1 0.0141178
SERINC1 serine incorporator 1 0.0141006
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.0140971
CEP85L centrosomal protein 85kDa-like 0.0140577
NLK nemo-like kinase 0.0140422
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0140168
TPM2 tropomyosin 2 (beta) 0.0140148
SAMD1 sterile alpha motif domain containing 1 0.0140077
BMS1 BMS1 ribosome biogenesis factor 0.0140001
TMED4 transmembrane emp24 protein transport domain containing 4 0.0139816
FDPS farnesyl diphosphate synthase 0.0139812
DENND6A DENN/MADD domain containing 6A 0.0139722
ZFP36L1 ZFP36 ring finger protein-like 1 0.013956
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.0139487
GAN gigaxonin 0.0139348
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.0139319
RPS12 ribosomal protein S12 0.01389
MYRF myelin regulatory factor 0.0138474
AHNAK AHNAK nucleoprotein 0.0138429
STIP1 stress-induced phosphoprotein 1 0.0138275
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.0137815
TTC17 tetratricopeptide repeat domain 17 0.013779
KRCC1 lysine-rich coiled-coil 1 0.0137756
COPS3 COP9 signalosome subunit 3 0.0137403
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0137191
ZNF569 zinc finger protein 569 0.0136993
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.0136935
SSBP4 single stranded DNA binding protein 4 0.0136298
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 0.0136147
UBAP1 ubiquitin associated protein 1 0.0136131
ACADVL acyl-CoA dehydrogenase, very long chain 0.0136008
YY1AP1 YY1 associated protein 1 0.0135819
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0135607
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.0135437
CAV1 caveolin 1, caveolae protein, 22kDa 0.0135394
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0135326
RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.0135008
PHF14 PHD finger protein 14 0.0134998
EMP3 epithelial membrane protein 3 0.0134826
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0134643
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.0134562
TMEM19 transmembrane protein 19 0.0134497
OSBPL1A oxysterol binding protein-like 1A 0.0134169
FNBP1L formin binding protein 1-like 0.0134046
PAQR5 progestin and adipoQ receptor family member V 0.0133888
MEF2A myocyte enhancer factor 2A 0.0133872
ATP5MC3 ATP synthase membrane subunit c locus 3 0.0133035
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 0.0132811
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0132524
LITAF lipopolysaccharide-induced TNF factor 0.0132129
GLI2 GLI family zinc finger 2 0.0131899
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.0131558
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.0131462
ANXA2 annexin A2 0.0131326
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0131115
RPAP3 RNA polymerase II associated protein 3 0.0131057
VCP valosin containing protein 0.0130996
GALK2 galactokinase 2 0.0130981
LTBP3 latent transforming growth factor beta binding protein 3 0.0130937
EPN1 epsin 1 0.0130935
CLDN1 claudin 1 0.0130675
AQR aquarius intron-binding spliceosomal factor 0.0130579
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0130472
DCTN1 dynactin 1 0.0130455
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.0130417
OGA O-GlcNAcase 0.0130325
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.0130202
PSPC1 paraspeckle component 1 0.0130087
SCARB1 scavenger receptor class B, member 1 0.0129945
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.012988
WDR76 WD repeat domain 76 0.0129864
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0129772
ERH enhancer of rudimentary homolog (Drosophila) 0.0129733
SEPTIN9 septin 9 0.0129375
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 0.0129202
PSIP1 PC4 and SFRS1 interacting protein 1 0.0129078
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0128957
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.012883
RPRD1B regulation of nuclear pre-mRNA domain containing 1B 0.0128694
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.0128505

decreased expression

Symbol Name Standardized Value
FAM107B family with sequence similarity 107, member B -0.127841
PTGR1 prostaglandin reductase 1 -0.100919
CNTN1 contactin 1 -0.094445
TMOD3 tropomodulin 3 (ubiquitous) -0.079567
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0690954
EHBP1 EH domain binding protein 1 -0.0660596
FN1 fibronectin 1 -0.0650505
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0645064
WWOX WW domain containing oxidoreductase -0.0625989
NF1 neurofibromin 1 -0.0625525
MAML3 mastermind-like 3 (Drosophila) -0.0603392
KYNU kynureninase -0.0582834
SYT1 synaptotagmin I -0.0575343
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0564394
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0553956
CNTNAP3B contactin associated protein-like 3B -0.0540906
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0525283
PARD3 par-3 family cell polarity regulator -0.0523717
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0520911
LPP LIM domain containing preferred translocation partner in lipoma -0.0520685
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0509791
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0506384
ARHGAP5 Rho GTPase activating protein 5 -0.050052
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0498796
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0486483
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.0482937
THSD7A thrombospondin, type I, domain containing 7A -0.0481681
CUX1 cut-like homeobox 1 -0.0475987
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0472539
THSD4 thrombospondin, type I, domain containing 4 -0.0470877
SLC38A2 solute carrier family 38, member 2 -0.0465754
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0465144
TRAPPC9 trafficking protein particle complex 9 -0.0460137
EXOC6B exocyst complex component 6B -0.04557
TTC28 tetratricopeptide repeat domain 28 -0.0455495
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0454085
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0452791
RAB1A RAB1A, member RAS oncogene family -0.0450501
NCOR1 nuclear receptor corepressor 1 -0.0438046
LHFPL2 lipoma HMGIC fusion partner-like 2 -0.0435638
OPHN1 oligophrenin 1 -0.0431056
MTUS1 microtubule associated tumor suppressor 1 -0.0428861
PHF21A PHD finger protein 21A -0.042433
STX8 syntaxin 8 -0.0420579
TRIO trio Rho guanine nucleotide exchange factor -0.042025
R3HDM1 R3H domain containing 1 -0.0417659
METTL16 methyltransferase like 16 -0.0416494
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0414601
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0413712
PDZD8 PDZ domain containing 8 -0.0406549
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0403652
AFF4 AF4/FMR2 family, member 4 -0.0403163
BMPR1B bone morphogenetic protein receptor, type IB -0.0400513
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0395753
FOXP1 forkhead box P1 -0.0393208
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0387096
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0384659
GPC6 glypican 6 -0.0384115
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0383028
MTCL1 microtubule crosslinking factor 1 -0.0377066
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0372287
SLC39A11 solute carrier family 39, member 11 -0.0371572
ZCCHC7 zinc finger, CCHC domain containing 7 -0.037063
PTBP3 polypyrimidine tract binding protein 3 -0.0368359
TUBD1 tubulin, delta 1 -0.0366514
PPP1R9A protein phosphatase 1, regulatory subunit 9A -0.0366378
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0361127
ACBD6 acyl-CoA binding domain containing 6 -0.0359326
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -0.035699
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0350065
GCLC glutamate-cysteine ligase, catalytic subunit -0.0349418
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0348799
TAOK3 TAO kinase 3 -0.0347964
CHD9 chromodomain helicase DNA binding protein 9 -0.0347289
ARHGAP26 Rho GTPase activating protein 26 -0.0347135
MED13 mediator complex subunit 13 -0.0346272
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0346153
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0344992
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -0.0344284
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0342999
ETNK1 ethanolamine kinase 1 -0.0342179
UBE3C ubiquitin protein ligase E3C -0.0341853
MGLL monoglyceride lipase -0.033963
TANK TRAF family member-associated NFKB activator -0.0332986
CNKSR3 CNKSR family member 3 -0.0329309
PRKCA protein kinase C, alpha -0.032867
FTO fat mass and obesity associated -0.0327747
ZBTB20 zinc finger and BTB domain containing 20 -0.0326555
PTK2 protein tyrosine kinase 2 -0.0326238
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0325315
REEP3 receptor accessory protein 3 -0.0324557
IQGAP2 IQ motif containing GTPase activating protein 2 -0.0322868
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0322357
ZFHX3 zinc finger homeobox 3 -0.0315887
JMJD1C jumonji domain containing 1C -0.0313014
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0312502
CYRIB CYFIP related Rac1 interactor B -0.0312123
CD44 CD44 molecule (Indian blood group) -0.0309961
SSH2 slingshot protein phosphatase 2 -0.0307321
PDE4D phosphodiesterase 4D, cAMP-specific -0.0306657
APP amyloid beta (A4) precursor protein -0.0306535
CLDN2 claudin 2 -0.030515
SINHCAF SIN3-HDAC complex associated factor -0.0304008
COMMD10 COMM domain containing 10 -0.0303058
SFXN5 sideroflexin 5 -0.0301626
URI1 URI1, prefoldin-like chaperone -0.0301554
SUMF1 sulfatase modifying factor 1 -0.030088
ATE1 arginyltransferase 1 -0.029837
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.029789
AGFG1 ArfGAP with FG repeats 1 -0.029456
VEZT vezatin, adherens junctions transmembrane protein -0.0292919
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0292235
ABHD12 abhydrolase domain containing 12 -0.0291863
NCOA3 nuclear receptor coactivator 3 -0.028909
ATXN2 ataxin 2 -0.0284631
DNAAF9 dynein axonemal assembly factor 9 -0.0280072
SKIL SKI-like proto-oncogene -0.0277796
RPS9 ribosomal protein S9 -0.0275865
TRIM37 tripartite motif containing 37 -0.0273829
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 -0.0273549
CAMKMT calmodulin-lysine N-methyltransferase -0.0273098
CP ceruloplasmin (ferroxidase) -0.0272125
IGSF1 immunoglobulin superfamily, member 1 -0.0271389
PDE7B phosphodiesterase 7B -0.0269713
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0266254
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0266221
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0266147
TMEM131 transmembrane protein 131 -0.0264023
FAM13A family with sequence similarity 13, member A -0.0260561
POLK polymerase (DNA directed) kappa -0.0259803
PTPRM protein tyrosine phosphatase, receptor type, M -0.0258561
SH3PXD2A SH3 and PX domains 2A -0.0254621
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.025422
SMAD2 SMAD family member 2 -0.0254204
GRN granulin -0.0250552
DSCAM Down syndrome cell adhesion molecule -0.0249996
SPAG9 sperm associated antigen 9 -0.0249683
MRTFB myocardin related transcription factor B -0.0248479
GARRE1 granule associated Rac and RHOG effector 1 -0.0247477
USP34 ubiquitin specific peptidase 34 -0.0247444
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0247042
CCDC57 coiled-coil domain containing 57 -0.0246939
TASOR2 transcription activation suppressor family member 2 -0.0244225
SPIDR scaffolding protein involved in DNA repair -0.0243321
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0243181
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0243102
BCAS1 breast carcinoma amplified sequence 1 -0.0242486
MRPS25 mitochondrial ribosomal protein S25 -0.0241688
WDR44 WD repeat domain 44 -0.0241597
LMTK2 lemur tyrosine kinase 2 -0.024118
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.0240349
RDH10 retinol dehydrogenase 10 (all-trans) -0.0239081
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -0.0239036
CAMK2D calcium/calmodulin-dependent protein kinase II delta -0.023903
ZFYVE16 zinc finger, FYVE domain containing 16 -0.0238901
SPPL2A signal peptide peptidase like 2A -0.0237544
AKAP13 A kinase (PRKA) anchor protein 13 -0.0236799
HSDL2 hydroxysteroid dehydrogenase like 2 -0.0236119
POM121 POM121 transmembrane nucleoporin -0.0235681
RPL13A ribosomal protein L13a -0.0235652
CDC27 cell division cycle 27 -0.023396
ZFYVE9 zinc finger, FYVE domain containing 9 -0.0233765
KMT5B lysine methyltransferase 5B -0.023334
MLPH melanophilin -0.0233012
CLCN7 chloride channel, voltage-sensitive 7 -0.0232993
SLMAP sarcolemma associated protein -0.023226
RBM10 RNA binding motif protein 10 -0.0231104
CLMN calmin (calponin-like, transmembrane) -0.02302
IRS2 insulin receptor substrate 2 -0.023011
FAM120B family with sequence similarity 120B -0.0228914
MRPL13 mitochondrial ribosomal protein L13 -0.0228071
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.0227792
NTN4 netrin 4 -0.0227657
SCAMP2 secretory carrier membrane protein 2 -0.0227208
ARHGAP24 Rho GTPase activating protein 24 -0.0227146
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0226947
SIN3A SIN3 transcription regulator family member A -0.0226638
NONO non-POU domain containing, octamer-binding -0.0226381
CALD1 caldesmon 1 -0.0226292
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.0226211
SMOC1 SPARC related modular calcium binding 1 -0.0226039
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -0.0225265
CEMIP2 cell migration inducing hyaluronidase 2 -0.0224866
CPNE8 copine VIII -0.0224784
TET3 tet methylcytosine dioxygenase 3 -0.022477
CD99L2 CD99 molecule-like 2 -0.0224195
S100A11 S100 calcium binding protein A11 -0.0223841
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0223608
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0223463
NRG1 neuregulin 1 -0.0222792
NIPBL Nipped-B homolog (Drosophila) -0.022251
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0222452
NOP58 NOP58 ribonucleoprotein -0.0221084
FBXL2 F-box and leucine-rich repeat protein 2 -0.0220631
FBL fibrillarin -0.0219849
FGA fibrinogen alpha chain -0.0219304
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.0218437
IREB2 iron-responsive element binding protein 2 -0.0216847
CTBP2 C-terminal binding protein 2 -0.0216784
C1RL complement component 1, r subcomponent-like -0.021669
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -0.0215884
ANO6 anoctamin 6 -0.0215653
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0215325
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0214627
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.0214518
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0214183
SMG6 SMG6 nonsense mediated mRNA decay factor -0.021415
SETD5 SET domain containing 5 -0.021396
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0213444
NINL ninein-like -0.0213278
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -0.0212598
COMMD1 copper metabolism (Murr1) domain containing 1 -0.0212109
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0211834
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0210959
TPD52L1 tumor protein D52-like 1 -0.0210873
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.021084
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0209871
RPH3AL rabphilin 3A-like (without C2 domains) -0.0208332
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.0208211
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.0207831
FRYL FRY-like -0.0207361
PBRM1 polybromo 1 -0.0206971
LRP1B low density lipoprotein receptor-related protein 1B -0.0206531
SOS1 son of sevenless homolog 1 (Drosophila) -0.0205943
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0205877
SMC1A structural maintenance of chromosomes 1A -0.0205739
ATOSA atos homolog A -0.020555
STAU1 staufen double-stranded RNA binding protein 1 -0.0205458
EPAS1 endothelial PAS domain protein 1 -0.0205352
YBX3 Y box binding protein 3 -0.0205238
WDR41 WD repeat domain 41 -0.020411
UNK unkempt family zinc finger -0.0203868
ACACA acetyl-CoA carboxylase alpha -0.0202268
SMAD3 SMAD family member 3 -0.0201754
GEN1 GEN1 Holliday junction 5' flap endonuclease -0.0201425
RNF145 ring finger protein 145 -0.0200741
WDR35 WD repeat domain 35 -0.0200554
SFTPA2 surfactant protein A2 -0.0199989
TM7SF3 transmembrane 7 superfamily member 3 -0.0199862
ARTN artemin -0.0199088
GOLGA4 golgin A4 -0.0198856
KCNT2 potassium channel, sodium activated subfamily T, member 2 -0.0198251
CFLAR CASP8 and FADD-like apoptosis regulator -0.0198093
GRAMD1B GRAM domain containing 1B -0.0197342
TNRC6B trinucleotide repeat containing 6B -0.0197258
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.019723
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0197018
PHACTR2 phosphatase and actin regulator 2 -0.0197004
CPEB2 cytoplasmic polyadenylation element binding protein 2 -0.0196998
CD38 CD38 molecule -0.0196361
CDYL chromodomain protein, Y-like -0.0196334
MAP7 microtubule-associated protein 7 -0.0196261
POC1B POC1 centriolar protein B -0.0196077
AGO2 argonaute RISC catalytic component 2 -0.0195744
NBAS neuroblastoma amplified sequence -0.0195494
TBC1D4 TBC1 domain family, member 4 -0.019533
UBAP2 ubiquitin associated protein 2 -0.0194823
RAB2A RAB2A, member RAS oncogene family -0.0194129
NUMB numb homolog (Drosophila) -0.0193634
NCOR2 nuclear receptor corepressor 2 -0.019326
STK24 serine/threonine kinase 24 -0.0193259
HEATR5A HEAT repeat containing 5A -0.0193029
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0192991
LAMP2 lysosomal-associated membrane protein 2 -0.0192702
NUDCD3 NudC domain containing 3 -0.019197
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -0.0191861
NIPSNAP2 nipsnap homolog 2 -0.0191659
NBEA neurobeachin -0.019111
KSR1 kinase suppressor of ras 1 -0.0189561
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0189529
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0189436
NAP1L1 nucleosome assembly protein 1-like 1 -0.0189276
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0189127
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0188821
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0188594
LURAP1L leucine rich adaptor protein 1-like -0.0188387
HDLBP high density lipoprotein binding protein -0.0188329
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.0187616
PAWR PRKC, apoptosis, WT1, regulator -0.0187581
RAP1B RAP1B, member of RAS oncogene family -0.0187571
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0187509
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0187362
WAC WW domain containing adaptor with coiled-coil -0.0187124
RPL28 ribosomal protein L28 -0.0187067
SPICE1 spindle and centriole associated protein 1 -0.0187039
CAB39 calcium binding protein 39 -0.0186697
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0186172
ZNF644 zinc finger protein 644 -0.0186098
MECP2 methyl CpG binding protein 2 -0.0186031
FOSL2 FOS-like antigen 2 -0.0185537
ANKRD17 ankyrin repeat domain 17 -0.0185111
LRP6 low density lipoprotein receptor-related protein 6 -0.0184936
OSGIN2 oxidative stress induced growth inhibitor family member 2 -0.0184822
ABLIM1 actin binding LIM protein 1 -0.0184726
UBXN4 UBX domain protein 4 -0.0184596
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0184352
TOMM70 translocase of outer mitochondrial membrane 70 -0.0184053
TNRC18 trinucleotide repeat containing 18 -0.0183475
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0183094
HIP1 huntingtin interacting protein 1 -0.018308
GSR glutathione reductase -0.0182651
PLPP1 phospholipid phosphatase 1 -0.0182536
TGIF1 TGFB-induced factor homeobox 1 -0.0182515
LGALS12 lectin, galactoside-binding, soluble, 12 -0.018221
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -0.0182191
TJP1 tight junction protein 1 -0.01815
CHKA choline kinase alpha -0.0181357
IQSEC2 IQ motif and Sec7 domain 2 -0.018084
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -0.0180226
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) -0.0180222
FAM222B family with sequence similarity 222, member B -0.0180063
MACROD2 MACRO domain containing 2 -0.0179884
FBXO42 F-box protein 42 -0.0179797
P3H2 prolyl 3-hydroxylase 2 -0.0179643
SERINC5 serine incorporator 5 -0.0179167
MSRB3 methionine sulfoxide reductase B3 -0.0178283
FAM133B family with sequence similarity 133, member B -0.0177139
TUBGCP2 tubulin, gamma complex associated protein 2 -0.0177023
PDE8A phosphodiesterase 8A -0.0176987
RSBN1L round spermatid basic protein 1-like -0.0176703
TRAM1 translocation associated membrane protein 1 -0.0176414
PON3 paraoxonase 3 -0.0176347
ATG7 autophagy related 7 -0.0176206
SPACA6 sperm acrosome associated 6 -0.0176191
PCDHB16 protocadherin beta 16 -0.0176034
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0175816
NBEAL1 neurobeachin-like 1 -0.0175757
MLXIP MLX interacting protein -0.0175137
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0174789
RLF rearranged L-myc fusion -0.0174734
GPATCH8 G patch domain containing 8 -0.0174536
YAP1 Yes-associated protein 1 -0.0174516
VDAC2 voltage-dependent anion channel 2 -0.0174178
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0173846
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.0173275
STK38 serine/threonine kinase 38 -0.0173235
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0173161
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0172485
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0172456
FYCO1 FYVE and coiled-coil domain containing 1 -0.017177
NVL nuclear VCP-like -0.0171749
USP54 ubiquitin specific peptidase 54 -0.0171322
XRN1 5'-3' exoribonuclease 1 -0.0171005
ZFAND6 zinc finger, AN1-type domain 6 -0.0170751
SYNJ2 synaptojanin 2 -0.0170709
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0170204
IER3 immediate early response 3 -0.0169405
RAI14 retinoic acid induced 14 -0.0168924
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0168903
SIL1 SIL1 nucleotide exchange factor -0.0168834
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.0168568
FANCL Fanconi anemia, complementation group L -0.0168485
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0168476
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0168236
SHTN1 shootin 1 -0.0167954
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase -0.0167702
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.01677
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.016758
BTG1 B-cell translocation gene 1, anti-proliferative -0.0167138
RBM5 RNA binding motif protein 5 -0.0167124
MPHOSPH8 M-phase phosphoprotein 8 -0.0166783
TNPO2 transportin 2 -0.0166598
ELF2 E74-like factor 2 (ets domain transcription factor) -0.0166502
ARB2A ARB2 cotranscriptional regulator A -0.0166342
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.0166111
BRD4 bromodomain containing 4 -0.0166038
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -0.0165775
RBM33 RNA binding motif protein 33 -0.0165742
TRUB2 TruB pseudouridine (psi) synthase family member 2 -0.0165704
SCAPER S-phase cyclin A-associated protein in the ER -0.0165697
RNF43 ring finger protein 43 -0.0165643
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0165604
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0165377
ARL15 ADP-ribosylation factor-like 15 -0.016536
CDK7 cyclin-dependent kinase 7 -0.0165253
TBC1D15 TBC1 domain family, member 15 -0.0165142
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 -0.0165087
SH3KBP1 SH3-domain kinase binding protein 1 -0.0165052
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0164902
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0164621
ARID4A AT rich interactive domain 4A (RBP1-like) -0.0164562
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0164389
CUEDC1 CUE domain containing 1 -0.0163997
CNTNAP3 contactin associated protein-like 3 -0.0163949
DAPK1 death-associated protein kinase 1 -0.016393
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -0.0163875
CHD1 chromodomain helicase DNA binding protein 1 -0.0163618
CLOCK clock circadian regulator -0.0163013
SKP1 S-phase kinase-associated protein 1 -0.0162682
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.016257
SLTM SAFB-like, transcription modulator -0.016255
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0162428
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -0.0162241
LMNB2 lamin B2 -0.016201
WDFY2 WD repeat and FYVE domain containing 2 -0.0161639
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.0161191
CCDC138 coiled-coil domain containing 138 -0.0161173
CENPP centromere protein P -0.0161106
RB1CC1 RB1-inducible coiled-coil 1 -0.0160939
BHLHE40 basic helix-loop-helix family, member e40 -0.0160849
SESTD1 SEC14 and spectrin domains 1 -0.0160593
STOX2 storkhead box 2 -0.0160472
TXNRD1 thioredoxin reductase 1 -0.0160374
FAM168A family with sequence similarity 168, member A -0.0160133
SCRN1 secernin 1 -0.0160076
BMAL1 basic helix-loop-helix ARNT like 1 -0.0159646
CUL3 cullin 3 -0.0159597
ADIPOR2 adiponectin receptor 2 -0.0159593
WWC2 WW and C2 domain containing 2 -0.0159417
DENND1B DENN/MADD domain containing 1B -0.0159355
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.015921
AMBRA1 autophagy/beclin-1 regulator 1 -0.0159204
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -0.0159129
GRAMD1A GRAM domain containing 1A -0.015898
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.01587
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0157723
NUP62 nucleoporin 62kDa -0.0157583
D2HGDH D-2-hydroxyglutarate dehydrogenase -0.0157481
CLIP4 CAP-GLY domain containing linker protein family, member 4 -0.0157383
PSEN1 presenilin 1 -0.015731
AGGF1 angiogenic factor with G patch and FHA domains 1 -0.015709
DCAF6 DDB1 and CUL4 associated factor 6 -0.015696
MTRFR mitochondrial translation release factor in rescue -0.0156942
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -0.015684
FAM161A family with sequence similarity 161, member A -0.0156541
ENSA endosulfine alpha -0.0156488
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0156454
ENAH enabled homolog (Drosophila) -0.0156425
MPZ myelin protein zero -0.015637
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.015635
LAMA5 laminin, alpha 5 -0.0156276
EVA1C eva-1 homolog C (C. elegans) -0.0155764
GLE1 GLE1 RNA export mediator -0.015566
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.0155658
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 -0.0155504
TOR1B torsin family 1, member B (torsin B) -0.0155267
USP24 ubiquitin specific peptidase 24 -0.0155253
THADA thyroid adenoma associated -0.0154046
SLC71A2 solute carrier family 71 member 2 -0.015396
ZSCAN5A zinc finger and SCAN domain containing 5A -0.0153931
SAE1 SUMO1 activating enzyme subunit 1 -0.0153921
TP63 tumor protein p63 -0.0153777
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -0.0153708
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.015311
ZNF367 zinc finger protein 367 -0.0153099
HM13 histocompatibility (minor) 13 -0.0152593
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.0152384
ATRN attractin -0.0152381
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -0.015231
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0152158
CCNYL1 cyclin Y-like 1 -0.0152006
DNAH14 dynein, axonemal, heavy chain 14 -0.0151852
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.0151847
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0151617
DTNB dystrobrevin, beta -0.0151328
AURKAIP1 aurora kinase A interacting protein 1 -0.0151166
RSU1 Ras suppressor protein 1 -0.0151071
SFPQ splicing factor proline/glutamine-rich -0.0150979
HIPK2 homeodomain interacting protein kinase 2 -0.0150822
RNASE3 ribonuclease, RNase A family, 3 -0.0150817
STX16 syntaxin 16 -0.0150801
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -0.0150556
FILIP1 filamin A interacting protein 1 -0.0150515
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0150493
SCAI suppressor of cancer cell invasion -0.0150412
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.015035
FLOT1 flotillin 1 -0.0150267
PCNX4 pecanex 4 -0.0150255
BEND7 BEN domain containing 7 -0.0150191
STK39 serine threonine kinase 39 -0.0150029
DPYD dihydropyrimidine dehydrogenase -0.0149951
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.0149435
PRPF4 pre-mRNA processing factor 4 -0.0149391
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.0149223
EMC4 ER membrane protein complex subunit 4 -0.0149203
EIF3D eukaryotic translation initiation factor 3, subunit D -0.0148893
RFWD3 ring finger and WD repeat domain 3 -0.0148695
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -0.0148617
SOX4 SRY (sex determining region Y)-box 4 -0.0148617
MYO10 myosin X -0.0148615
DZANK1 double zinc ribbon and ankyrin repeat domains 1 -0.0148545
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0148487
NCOA2 nuclear receptor coactivator 2 -0.0148159
MCM3 minichromosome maintenance complex component 3 -0.0148042
TES testin LIM domain protein -0.0148028
TGFBR3 transforming growth factor, beta receptor III -0.0148008
MRE11 MRE11 homolog, double strand break repair nuclease -0.0147985
SLC49A4 solute carrier family 49 member 4 -0.0147949
RPL23 ribosomal protein L23 -0.0147861
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.0147788
POGZ pogo transposable element with ZNF domain -0.0147595
CNOT9 CCR4-NOT transcription complex subunit 9 -0.0147321
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.0147319
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0146838
CPLX2 complexin 2 -0.0146795
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.014665
SRPK1 SRSF protein kinase 1 -0.0146538
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0146447
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0146433
NUP54 nucleoporin 54kDa -0.0146106