A549_Obatoclax Mesylate_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Obatoclax Mesylate 10µM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_Obatoclax Mesylate_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.25602
TXNRD1 thioredoxin reductase 1 0.176846
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.161646
SQSTM1 sequestosome 1 0.133371
MAP1B microtubule-associated protein 1B 0.0975879
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0951522
NQO1 NAD(P)H dehydrogenase, quinone 1 0.0851227
FTL ferritin, light polypeptide 0.0828318
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0827733
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0805515
MUSK muscle, skeletal, receptor tyrosine kinase 0.0784623
KRT81 keratin 81, type II 0.0739265
RPLP1 ribosomal protein, large, P1 0.0707662
LOC112694756 uncharaterized LOC112694756 0.0696144
PKM pyruvate kinase, muscle 0.0687683
VIM vimentin 0.0675475
AHNAK2 AHNAK nucleoprotein 2 0.061794
RPL13A ribosomal protein L13a 0.0616253
RPS16 ribosomal protein S16 0.0592709
UBC ubiquitin C 0.0586244
ANKRD11 ankyrin repeat domain 11 0.0585874
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0557106
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0536763
FMNL2 formin-like 2 0.0521047
SLC38A1 solute carrier family 38, member 1 0.0518442
RAB3B RAB3B, member RAS oncogene family 0.0515216
FNDC3B fibronectin type III domain containing 3B 0.0511198
UBL4A ubiquitin-like 4A 0.051106
UBASH3B ubiquitin associated and SH3 domain containing B 0.0510935
FTH1 ferritin, heavy polypeptide 1 0.0476253
NRG1 neuregulin 1 0.0465145
RPL15 ribosomal protein L15 0.0463446
DENND4C DENN/MADD domain containing 4C 0.0456451
TMEM156 transmembrane protein 156 0.0454147
RAI14 retinoic acid induced 14 0.0444905
MAP4 microtubule-associated protein 4 0.0438055
KPNB1 karyopherin (importin) beta 1 0.0427902
HIPK2 homeodomain interacting protein kinase 2 0.0421906
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0409533
PLEC plectin 0.0408731
TRIO trio Rho guanine nucleotide exchange factor 0.040095
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.0400027
TKT transketolase 0.0390492
EREG epiregulin 0.0379757
KTN1 kinectin 1 (kinesin receptor) 0.0375968
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.037266
GCLM glutamate-cysteine ligase, modifier subunit 0.0372461
NTN4 netrin 4 0.0372054
ZFP36L1 ZFP36 ring finger protein-like 1 0.0370403
CEP350 centrosomal protein 350kDa 0.0369775
ACTG1 actin gamma 1 0.0367384
FDPS farnesyl diphosphate synthase 0.0365374
RORA RAR-related orphan receptor A 0.0362687
TMSB10 thymosin beta 10 0.0362103
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0362023
ACSS2 acyl-CoA synthetase short-chain family member 2 0.0357918
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0356631
AKAP12 A kinase (PRKA) anchor protein 12 0.0356027
LDHA lactate dehydrogenase A 0.0350463
MRPL13 mitochondrial ribosomal protein L13 0.0348529
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0347692
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0347161
UBB ubiquitin B 0.0340762
FASN fatty acid synthase 0.0340412
RPL28 ribosomal protein L28 0.0334109
RB1CC1 RB1-inducible coiled-coil 1 0.032987
RPL37A ribosomal protein L37a 0.0327464
NRIP1 nuclear receptor interacting protein 1 0.0327441
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0325862
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0321417
PRDX1 peroxiredoxin 1 0.032073
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0314895
AGFG1 ArfGAP with FG repeats 1 0.0314028
LPIN1 lipin 1 0.0310802
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0309679
AUTS2 autism susceptibility candidate 2 0.0309016
RPS8 ribosomal protein S8 0.0308794
MTDH metadherin 0.0302693
MYADM myeloid-associated differentiation marker 0.0302432
GRB2 growth factor receptor-bound protein 2 0.0302075
HMGA1 high mobility group AT-hook 1 0.0299291
ALCAM activated leukocyte cell adhesion molecule 0.0292868
PCDH9 protocadherin 9 0.029236
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0292062
BMERB1 bMERB domain containing 1 0.0289842
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0287545
USP34 ubiquitin specific peptidase 34 0.0286304
LARP1 La ribonucleoprotein domain family, member 1 0.0285995
TJP1 tight junction protein 1 0.0285517
CAVIN1 caveolae associated protein 1 0.028496
GLIS3 GLIS family zinc finger 3 0.0284395
DSTN destrin (actin depolymerizing factor) 0.0281955
AKAP13 A kinase (PRKA) anchor protein 13 0.028069
CEMIP cell migration inducing protein, hyaluronan binding 0.0280322
TPM3 tropomyosin 3 0.0280289
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0280141
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0279489
ENO1 enolase 1, (alpha) 0.0278766
IARS1 isoleucyl-tRNA synthetase 1 0.0275326
RPL12 ribosomal protein L12 0.0272414
GCLC glutamate-cysteine ligase, catalytic subunit 0.0270626
RPL38 ribosomal protein L38 0.0268719
TMEM41B transmembrane protein 41B 0.0267344
KIAA0319L KIAA0319-like 0.0266233
AKR1C1 aldo-keto reductase family 1, member C1 0.0265853
MBNL1 muscleblind-like splicing regulator 1 0.0264725
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0264008
SQLE squalene epoxidase 0.0262605
LMO7 LIM domain 7 0.0262375
RSL1D1 ribosomal L1 domain containing 1 0.0261816
RPL23A ribosomal protein L23a 0.026154
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0259089
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0257644
DHCR7 7-dehydrocholesterol reductase 0.0256463
ECPAS Ecm29 proteasome adaptor and scaffold 0.02562
IRAK2 interleukin-1 receptor-associated kinase 2 0.025605
ASPH aspartate beta-hydroxylase 0.0254985
RPSA ribosomal protein SA 0.0254785
RPS5 ribosomal protein S5 0.0254007
TPI1 triosephosphate isomerase 1 0.0253212
CANX calnexin 0.02528
NAMPT nicotinamide phosphoribosyltransferase 0.0251643
ITGB5 integrin, beta 5 0.0251548
RACK1 receptor for activated C kinase 1 0.0250307
MYO9A myosin IXA 0.0245273
CCNI cyclin I 0.0244877
KAT6B K(lysine) acetyltransferase 6B 0.0244089
VGLL4 vestigial-like family member 4 0.0243377
NFE2L1 nuclear factor, erythroid 2-like 1 0.0240321
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0238989
RPS6 ribosomal protein S6 0.0238818
UNC13A unc-13 homolog A (C. elegans) 0.0237461
WNT7B wingless-type MMTV integration site family, member 7B 0.0237276
RPS2 ribosomal protein S2 0.0235051
LDLR low density lipoprotein receptor 0.0234278
PCNX2 pecanex 2 0.023356
TUBA1B tubulin, alpha 1b 0.0232732
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0230367
GOLGA2 golgin A2 0.0229
SH3KBP1 SH3-domain kinase binding protein 1 0.0228912
RPL27A ribosomal protein L27a 0.022635
KCTD1 potassium channel tetramerization domain containing 1 0.0225571
NRP1 neuropilin 1 0.0224567
ARHGAP5 Rho GTPase activating protein 5 0.0223768
APP amyloid beta (A4) precursor protein 0.0223258
NPEPPS aminopeptidase puromycin sensitive 0.0223074
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0222829
DDIT4 DNA-damage-inducible transcript 4 0.0221803
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0220026
KMT2A lysine (K)-specific methyltransferase 2A 0.0219788
GNAS GNAS complex locus 0.0219663
RSF1 remodeling and spacing factor 1 0.0219225
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.021661
HSPA8 heat shock 70kDa protein 8 0.0216434
SFTPA2 surfactant protein A2 0.021613
SLK STE20-like kinase 0.0215848
ATXN1 ataxin 1 0.0215333
RPS9 ribosomal protein S9 0.0214943
COPA coatomer protein complex, subunit alpha 0.0214555
DNM3 dynamin 3 0.0214509
RNPS1 RNA binding protein S1, serine-rich domain 0.0213589
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.0213575
EEF2 eukaryotic translation elongation factor 2 0.0212688
PRRC2C proline-rich coiled-coil 2C 0.0212666
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 0.0212552
RPL27 ribosomal protein L27 0.0211273
NPC1 Niemann-Pick disease, type C1 0.0211258
FOXO1 forkhead box O1 0.0210979
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0210301
CLASP1 cytoplasmic linker associated protein 1 0.0209691
H3-3B H3.3 histone B 0.0209661
NCOA3 nuclear receptor coactivator 3 0.0209547
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.0209022
CXXC1 CXXC finger protein 1 0.0208661
DSPP dentin sialophosphoprotein 0.0206902
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0206705
HSPB1 heat shock 27kDa protein 1 0.020595
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.02056
EIF4B eukaryotic translation initiation factor 4B 0.0205338
ZFR zinc finger RNA binding protein 0.0205168
EML4 echinoderm microtubule associated protein like 4 0.0205008
EIF1 eukaryotic translation initiation factor 1 0.0204115
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.0204069
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0203728
SLTM SAFB-like, transcription modulator 0.0200457
VCP valosin containing protein 0.0200221
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0199812
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0199217
SKAP2 src kinase associated phosphoprotein 2 0.0198783
NPAS2 neuronal PAS domain protein 2 0.0196849
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0196564
SPAG9 sperm associated antigen 9 0.0196409
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.0196112
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.0194498
SLC35E3 solute carrier family 35, member E3 0.0193599
UBE2H ubiquitin-conjugating enzyme E2H 0.0193115
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0192922
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.019255
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.019201
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0191634
DCAF7 DDB1 and CUL4 associated factor 7 0.0191264
RPS11 ribosomal protein S11 0.019119
SLFN5 schlafen family member 5 0.0189455
KIF5B kinesin family member 5B 0.0189435
SND1 staphylococcal nuclease and tudor domain containing 1 0.018912
GLG1 golgi glycoprotein 1 0.0189024
GDF15 growth differentiation factor 15 0.0187975
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0187822
NAP1L1 nucleosome assembly protein 1-like 1 0.018741
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.0186948
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0186856
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0185819
COX5B cytochrome c oxidase subunit Vb 0.0185157
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0184952
CDK6 cyclin-dependent kinase 6 0.0184792
SMAD3 SMAD family member 3 0.0183471
KYNU kynureninase 0.0182905
CA12 carbonic anhydrase XII 0.0181191
GSK3B glycogen synthase kinase 3 beta 0.0180957
TARS1 threonyl-tRNA synthetase 1 0.0180823
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0180367
KMT2C lysine (K)-specific methyltransferase 2C 0.0179244
RPLP0 ribosomal protein, large, P0 0.0179173
RPL8 ribosomal protein L8 0.0178755
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0178749
SOS2 son of sevenless homolog 2 (Drosophila) 0.0178637
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.017861
RAB27B RAB27B, member RAS oncogene family 0.0178062
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.0177809
HMBOX1 homeobox containing 1 0.0175939
SLC35F3 solute carrier family 35, member F3 0.0175093
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.01748
SPOP speckle-type POZ protein 0.0174487
TRIB3 tribbles pseudokinase 3 0.0172946
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0171737
TMC5 transmembrane channel-like 5 0.017154
CHD8 chromodomain helicase DNA binding protein 8 0.01707
FGF13 fibroblast growth factor 13 0.017003
PLAAT3 phospholipase A and acyltransferase 3 0.0169692
LAMA4 laminin, alpha 4 0.0169638
PHGDH phosphoglycerate dehydrogenase 0.016943
WDR12 WD repeat domain 12 0.01692
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0168732
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.0168673
KIF1B kinesin family member 1B 0.0168397
EEIG1 estrogen-induced osteoclastogenesis regulator 1 0.0168073
RBM15 RNA binding motif protein 15 0.0167987
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0167058
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0166983
CREBBP CREB binding protein 0.0166916
TRAP1 TNF receptor-associated protein 1 0.016651
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.0166259
IFT54 intraflagellar transport 54 0.0165656
FBL fibrillarin 0.0164507
STAU1 staufen double-stranded RNA binding protein 1 0.0163931
TOM1L2 target of myb1-like 2 (chicken) 0.0163215
HCFC1 host cell factor C1 0.0162756
FLNB filamin B, beta 0.0162456
RNASE3 ribonuclease, RNase A family, 3 0.0162417
VDAC1 voltage-dependent anion channel 1 0.0161877
RPL7A ribosomal protein L7a 0.016135
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0160749
RNF10 ring finger protein 10 0.0160672
HSPH1 heat shock 105kDa/110kDa protein 1 0.0160562
RPLP2 ribosomal protein, large, P2 0.0160183
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0159966
IQGAP1 IQ motif containing GTPase activating protein 1 0.0159596
TMPRSS4 transmembrane protease, serine 4 0.0159291
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.0159082
EEA1 early endosome antigen 1 0.0158568
UBAP2 ubiquitin associated protein 2 0.0158161
MFSD12 major facilitator superfamily domain containing 12 0.0157831
BBX bobby sox homolog (Drosophila) 0.0157562
EXT1 exostosin glycosyltransferase 1 0.0157089
ECE1 endothelin converting enzyme 1 0.0156687
ITSN2 intersectin 2 0.0155898
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0155699
GPR39 G protein-coupled receptor 39 0.01555
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.0155303
MYO1B myosin IB 0.015522
SNX9 sorting nexin 9 0.01549
IKBIP IKBKB interacting protein 0.0152541
KIF2A kinesin heavy chain member 2A 0.0152071
TPT1 tumor protein, translationally-controlled 1 0.0152015
DST dystonin 0.0151802
MYO5C myosin VC 0.0151371
SHARPIN SHANK-associated RH domain interactor 0.0150951
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.015078
RPL11 ribosomal protein L11 0.0150151
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0150145
NECTIN3 nectin cell adhesion molecule 3 0.0150054
SERINC3 serine incorporator 3 0.0149883
SMC4 structural maintenance of chromosomes 4 0.0149846
KRT19 keratin 19, type I 0.0149789
FBXO11 F-box protein 11 0.0149325
UBP1 upstream binding protein 1 (LBP-1a) 0.014926
CLTC clathrin, heavy chain (Hc) 0.0148872
CHD9 chromodomain helicase DNA binding protein 9 0.0148676
FA2H fatty acid 2-hydroxylase 0.0148556
FNBP1 formin binding protein 1 0.0148206
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0148164
SCAF11 SR-related CTD-associated factor 11 0.0147167
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.0146213
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0146025
UBQLN1 ubiquilin 1 0.0145458
NCOA7 nuclear receptor coactivator 7 0.0145216
BICD1 bicaudal D homolog 1 (Drosophila) 0.014505
RPS7 ribosomal protein S7 0.0144906
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 0.0144871
RPS19 ribosomal protein S19 0.0144867
IGFBP1 insulin-like growth factor binding protein 1 0.0144854
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0144828
ZNF148 zinc finger protein 148 0.0144603
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0144278
CALCOCO2 calcium binding and coiled-coil domain 2 0.0144165
AMBRA1 autophagy/beclin-1 regulator 1 0.0143931
TTC3 tetratricopeptide repeat domain 3 0.0143665
CD2AP CD2-associated protein 0.0142726
RPS18 ribosomal protein S18 0.0142667
PARD6B par-6 family cell polarity regulator beta 0.01421
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.0141769
TNS3 tensin 3 0.0141627
OSBPL8 oxysterol binding protein-like 8 0.0141528
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0141225
KRT7 keratin 7, type II 0.0141182
POU2F1 POU class 2 homeobox 1 0.0141106
INTS10 integrator complex subunit 10 0.0140657
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0140283
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.0140209
STXBP1 syntaxin binding protein 1 0.0140017
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.0139959
TCEA1 transcription elongation factor A (SII), 1 0.0139871
WAPL WAPL cohesin release factor 0.0139823
KMT2E lysine (K)-specific methyltransferase 2E 0.0139804
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.013914
HAVCR1 hepatitis A virus cellular receptor 1 0.0139114
RPS23 ribosomal protein S23 0.0139058
LIN7A lin-7 homolog A (C. elegans) 0.0138316
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0138172
TMEM120B transmembrane protein 120B 0.0137788
TMEM131 transmembrane protein 131 0.0137731
MESD mesoderm development LRP chaperone 0.0137715
IRF2BPL interferon regulatory factor 2 binding protein-like 0.0137451
AREG amphiregulin 0.0137241
MINK1 misshapen-like kinase 1 0.0137223
NEBL nebulette 0.0137024
KDM4B lysine (K)-specific demethylase 4B 0.0136552
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0136487
MGST1 microsomal glutathione S-transferase 1 0.0135962
RANBP2 RAN binding protein 2 0.0135731
ZNF367 zinc finger protein 367 0.0135719
S100A6 S100 calcium binding protein A6 0.0135514
URI1 URI1, prefoldin-like chaperone 0.0134726
TASOR2 transcription activation suppressor family member 2 0.0134588
ZNF654 zinc finger protein 654 0.0134074
RABGAP1 RAB GTPase activating protein 1 0.0133902
KLHL42 kelch-like family member 42 0.013378
PRXL2A peroxiredoxin like 2A 0.0133653
TIAM2 T-cell lymphoma invasion and metastasis 2 0.0133404
RAN RAN, member RAS oncogene family 0.0133103
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0132899
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.013258
CTSL cathepsin L 0.0132321
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0131443
RARS1 arginyl-tRNA synthetase 1 0.0131352
ABHD2 abhydrolase domain containing 2 0.0131227
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.013117
RPS29 ribosomal protein S29 0.013047
SON SON DNA binding protein 0.01303
RHOQ ras homolog family member Q 0.0130252
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0130076
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.0129655
HM13 histocompatibility (minor) 13 0.0129649
NDRG1 N-myc downstream regulated 1 0.0129602
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.0129595
DTNB dystrobrevin, beta 0.0129233
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0128842
UBE3A ubiquitin protein ligase E3A 0.0128829
COTL1 coactosin-like F-actin binding protein 1 0.0128732
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.0128175
FUS FUS RNA binding protein 0.0128034
COBL cordon-bleu WH2 repeat protein 0.0127875
VEGFB vascular endothelial growth factor B 0.0127818
SECISBP2L SECIS binding protein 2-like 0.0127543
PLIN3 perilipin 3 0.0127534
RPL31 ribosomal protein L31 0.0127443
NONO non-POU domain containing, octamer-binding 0.0127195
CUL2 cullin 2 0.0127183
EVL Enah/Vasp-like 0.0127163
ARF3 ADP-ribosylation factor 3 0.0126774
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0126657
PRDM2 PR domain containing 2, with ZNF domain 0.0126125
PHPT1 phosphohistidine phosphatase 1 0.0126012
UBE4B ubiquitination factor E4B 0.0125945
HPS3 Hermansky-Pudlak syndrome 3 0.0125773
WBP1L WW domain binding protein 1-like 0.0125722
RPS21 ribosomal protein S21 0.0125641
GATAD1 GATA zinc finger domain containing 1 0.0125477
BCOR BCL6 corepressor 0.01252
HILPDA hypoxia inducible lipid droplet-associated 0.0125146
ATF4 activating transcription factor 4 0.0125004
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.0124966
ZMAT3 zinc finger, matrin-type 3 0.012463
ARHGAP35 Rho GTPase activating protein 35 0.0124523
ANO10 anoctamin 10 0.0124472
KIAA0319 KIAA0319 0.0124404
ERP44 endoplasmic reticulum protein 44 0.0124316
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.012417
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.0124163
SOS1 son of sevenless homolog 1 (Drosophila) 0.0124072
STK32B serine/threonine kinase 32B 0.0124035
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 0.0123739
HELZ helicase with zinc finger 0.0123734
RAD21 RAD21 homolog (S. pombe) 0.0123707
BLTP1 bridge-like lipid transfer protein family member 1 0.0123649
CCDC6 coiled-coil domain containing 6 0.0123245
SFPQ splicing factor proline/glutamine-rich 0.0123147
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0123135
ALKBH5 AlkB family member 5, RNA demethylase 0.0122895
NBAS neuroblastoma amplified sequence 0.012217
HP1BP3 heterochromatin protein 1, binding protein 3 0.0121973
TBCA tubulin folding cofactor A 0.0121887
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.0121557
RARB retinoic acid receptor, beta 0.0121514
TMEM123 transmembrane protein 123 0.012151
KANK2 KN motif and ankyrin repeat domains 2 0.0121442
MORC4 MORC family CW-type zinc finger 4 0.0121415
SET SET nuclear proto-oncogene 0.0121385
UBN2 ubinuclein 2 0.0121057
THRAP3 thyroid hormone receptor associated protein 3 0.0120273
MEF2A myocyte enhancer factor 2A 0.0120251
NOL10 nucleolar protein 10 0.0120223
SESN2 sestrin 2 0.0119922
ACADVL acyl-CoA dehydrogenase, very long chain 0.011974
EIF4E eukaryotic translation initiation factor 4E 0.0119668
RPL30 ribosomal protein L30 0.0119656
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.0119625
BRD2 bromodomain containing 2 0.0119536
SHISA5 shisa family member 5 0.0119304
KRTAP11-1 keratin associated protein 11-1 0.0119238
RNASEH1 ribonuclease H1 0.0119134
LIMS1 LIM and senescent cell antigen-like domains 1 0.0118686
IER2 immediate early response 2 0.0118374
DGKG diacylglycerol kinase, gamma 90kDa 0.0118234
CA8 carbonic anhydrase VIII 0.0118189
YAP1 Yes-associated protein 1 0.0117668
S100A11 S100 calcium binding protein A11 0.0117594
ASCC1 activating signal cointegrator 1 complex subunit 1 0.0117211
SIL1 SIL1 nucleotide exchange factor 0.0116982
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0116641
STK10 serine/threonine kinase 10 0.0116582
AATF apoptosis antagonizing transcription factor 0.0116418
VEZT vezatin, adherens junctions transmembrane protein 0.0116146
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0116006
SNX29 sorting nexin 29 0.0115574
RPS3 ribosomal protein S3 0.0115432
BHLHE40 basic helix-loop-helix family, member e40 0.0115078
NBR1 neighbor of BRCA1 gene 1 0.0115032
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0114815
AGPS alkylglycerone phosphate synthase 0.0114661
TXNL1 thioredoxin-like 1 0.0114521
TOM1L1 target of myb1 (chicken)-like 1 0.0114348
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.0114283
LGALS3 lectin, galactoside-binding, soluble, 3 0.0113778
PRNP prion protein 0.0113672
QKI QKI, KH domain containing, RNA binding 0.0113652
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.0113489
MAP2K1 mitogen-activated protein kinase kinase 1 0.0113442
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0113387
MRPL19 mitochondrial ribosomal protein L19 0.0113336
WDR33 WD repeat domain 33 0.0113326
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0113254
CSNK1A1 casein kinase 1, alpha 1 0.0113223
PDCD6IP programmed cell death 6 interacting protein 0.0113027
MSN moesin 0.0112977
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.0112692
ZCCHC17 zinc finger, CCHC domain containing 17 0.0112561
COG8 component of oligomeric golgi complex 8 0.0112298
AHNAK AHNAK nucleoprotein 0.0112195
SEPTIN6 septin 6 0.0112045
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0111993
MATN2 matrilin 2 0.0111984
IFT172 intraflagellar transport 172 0.0111691
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.011168
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 0.0111608
SRBD1 S1 RNA binding domain 1 0.0111312
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.0111227
CLIP4 CAP-GLY domain containing linker protein family, member 4 0.0111166
MLF2 myeloid leukemia factor 2 0.0111126
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0111075
FOXP1 forkhead box P1 0.0110904
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0110832
LARP4B La ribonucleoprotein domain family, member 4B 0.0110713
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.011071
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0110673
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.0110548
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0110541
ILF3 interleukin enhancer binding factor 3, 90kDa 0.0110394
CDC73 cell division cycle 73 0.0110188
RUNDC1 RUN domain containing 1 0.0110145

decreased expression

Symbol Name Standardized Value
PDE4D phosphodiesterase 4D, cAMP-specific -0.195182
PDE10A phosphodiesterase 10A -0.136873
MYO1E myosin IE -0.126512
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.107325
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.104318
PTGR1 prostaglandin reductase 1 -0.100529
CUX1 cut-like homeobox 1 -0.0930289
CNTN1 contactin 1 -0.0926499
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0776988
FN1 fibronectin 1 -0.0750188
EHBP1 EH domain binding protein 1 -0.0711692
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0711645
JMJD1C jumonji domain containing 1C -0.0701975
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0701751
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -0.0693372
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0680193
MTUS1 microtubule associated tumor suppressor 1 -0.0676197
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0654572
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0650404
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0648875
ANXA4 annexin A4 -0.0641513
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0584016
RAB10 RAB10, member RAS oncogene family -0.0576044
IGF1R insulin-like growth factor 1 receptor -0.0573927
WWOX WW domain containing oxidoreductase -0.0567762
MAP7 microtubule-associated protein 7 -0.0557639
MYO10 myosin X -0.0543655
PDE4B phosphodiesterase 4B, cAMP-specific -0.0512106
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0492905
AGR2 anterior gradient 2 -0.0480063
GPATCH8 G patch domain containing 8 -0.0477967
BCL2L1 BCL2-like 1 -0.0477359
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0476925
MED13L mediator complex subunit 13-like -0.0470888
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0443788
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0441864
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0440327
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0433574
CNTNAP3B contactin associated protein-like 3B -0.0427102
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0417398
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0414384
TTC17 tetratricopeptide repeat domain 17 -0.0411417
ELMO1 engulfment and cell motility 1 -0.0409706
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0403245
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0394778
CNKSR3 CNKSR family member 3 -0.0392583
FAM107B family with sequence similarity 107, member B -0.0387133
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 -0.037249
BCAS3 breast carcinoma amplified sequence 3 -0.0366945
TPM4 tropomyosin 4 -0.0366872
NFIA nuclear factor I/A -0.0366452
EVA1C eva-1 homolog C (C. elegans) -0.0359675
WWC1 WW and C2 domain containing 1 -0.0356454
SPIDR scaffolding protein involved in DNA repair -0.0351982
CLU clusterin -0.0350654
ARHGAP26 Rho GTPase activating protein 26 -0.0346227
PKP4 plakophilin 4 -0.0345147
NT5C2 5'-nucleotidase, cytosolic II -0.0341548
RBM47 RNA binding motif protein 47 -0.0338277
TM4SF20 transmembrane 4 L six family member 20 -0.0329913
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0325442
KRT8 keratin 8, type II -0.032499
SLC39A11 solute carrier family 39, member 11 -0.0324322
BASP1 brain abundant, membrane attached signal protein 1 -0.0321106
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0306956
AOPEP aminopeptidase O (putative) -0.0305695
FILIP1 filamin A interacting protein 1 -0.0304433
CMIP c-Maf inducing protein -0.030234
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0302055
EZR ezrin -0.0299888
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0296417
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0290823
LITAF lipopolysaccharide-induced TNF factor -0.0286405
ABTB3 ankyrin repeat and BTB domain containing 3 -0.0283757
PM20D1 peptidase M20 domain containing 1 -0.0280864
SEPTIN9 septin 9 -0.0277726
ARHGAP12 Rho GTPase activating protein 12 -0.0275821
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.0275565
BICC1 BicC family RNA binding protein 1 -0.0271108
PDE7B phosphodiesterase 7B -0.0270755
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0268563
ANXA2 annexin A2 -0.0268366
CLIP1 CAP-GLY domain containing linker protein 1 -0.0266398
ZBTB20 zinc finger and BTB domain containing 20 -0.0262746
LRPPRC leucine-rich pentatricopeptide repeat containing -0.025957
LRMDA leucine rich melanocyte differentiation associated -0.0259085
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0254561
OPHN1 oligophrenin 1 -0.0250893
SRPK1 SRSF protein kinase 1 -0.0250832
BMPR1B bone morphogenetic protein receptor, type IB -0.0245347
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0245176
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0244541
PTGES2 prostaglandin E synthase 2 -0.0244298
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0243417
GPC6 glypican 6 -0.0243333
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0242121
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0240865
MACROD2 MACRO domain containing 2 -0.0240111
IGFBP4 insulin-like growth factor binding protein 4 -0.0238699
MSH3 mutS homolog 3 -0.0238473
SNAP25 synaptosomal-associated protein, 25kDa -0.0238289
FOXK1 forkhead box K1 -0.0235093
PBX1 pre-B-cell leukemia homeobox 1 -0.0234638
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0233489
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.023323
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0232815
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0230652
SETBP1 SET binding protein 1 -0.0229715
MCU mitochondrial calcium uniporter -0.0229448
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0228186
CLDN2 claudin 2 -0.0228153
KIF13B kinesin family member 13B -0.0225742
SBF2 SET binding factor 2 -0.0223821
FGB fibrinogen beta chain -0.022346
GMDS GDP-mannose 4,6-dehydratase -0.0223381
TNRC6A trinucleotide repeat containing 6A -0.0223241
FAF2 Fas associated factor family member 2 -0.0222777
SLC45A4 solute carrier family 45, member 4 -0.0222256
UBE2K ubiquitin-conjugating enzyme E2K -0.0222204
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0221589
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0220872
TNPO3 transportin 3 -0.0220861
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0218274
PON2 paraoxonase 2 -0.0217918
HGD homogentisate 1,2-dioxygenase -0.0216896
MLPH melanophilin -0.0214953
LIMCH1 LIM and calponin homology domains 1 -0.021494
FGA fibrinogen alpha chain -0.0214411
FANCI Fanconi anemia, complementation group I -0.0213957
IFT88 intraflagellar transport 88 -0.0213447
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0211004
MDN1 MDN1, midasin homolog (yeast) -0.0208778
ADNP activity-dependent neuroprotector homeobox -0.0208114
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -0.020559
PDE8A phosphodiesterase 8A -0.0204147
STAG2 stromal antigen 2 -0.0203547
FTO fat mass and obesity associated -0.0203174
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0202687
ARID1A AT rich interactive domain 1A (SWI-like) -0.0202291
TM4SF1 transmembrane 4 L six family member 1 -0.0202227
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -0.0201081
GPHN gephyrin -0.0200256
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.0199916
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0199694
NUP107 nucleoporin 107kDa -0.0199419
TM4SF4 transmembrane 4 L six family member 4 -0.0199169
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0198034
RFWD3 ring finger and WD repeat domain 3 -0.0196707
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.01964
CLASP2 cytoplasmic linker associated protein 2 -0.0196064
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.019511
TMEM135 transmembrane protein 135 -0.0194761
SMAD2 SMAD family member 2 -0.0194539
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.0194377
SINHCAF SIN3-HDAC complex associated factor -0.0193861
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.019326
PICALM phosphatidylinositol binding clathrin assembly protein -0.0192861
PDE7A phosphodiesterase 7A -0.0192537
TRIM37 tripartite motif containing 37 -0.0192297
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0192183
TCF12 transcription factor 12 -0.0192035
PRSS23 protease, serine, 23 -0.0191541
NCOA2 nuclear receptor coactivator 2 -0.0190257
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0190002
PRKCA protein kinase C, alpha -0.0189739
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -0.0187923
TXN2 thioredoxin 2 -0.018785
BABAM2 BRISC and BRCA1 A complex member 2 -0.018774
POC1B POC1 centriolar protein B -0.018773
FHIT fragile histidine triad -0.0187589
SLC22A23 solute carrier family 22, member 23 -0.0187347
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -0.0187182
KIFC3 kinesin family member C3 -0.0187119
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -0.0186842
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0185844
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.0185072
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.0184246
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0183983
SLC38A10 solute carrier family 38, member 10 -0.0183646
HEATR1 HEAT repeat containing 1 -0.0183567
MPG N-methylpurine-DNA glycosylase -0.0183526
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -0.0183373
NRCAM neuronal cell adhesion molecule -0.0183337
PROC protein C (inactivator of coagulation factors Va and VIIIa) -0.018331
C5 complement component 5 -0.0183163
MSI2 musashi RNA-binding protein 2 -0.0182837
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0182788
MYO19 myosin XIX -0.0182659
ANTXR1 anthrax toxin receptor 1 -0.0182137
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0182019
AHI1 Abelson helper integration site 1 -0.0181846
SFXN5 sideroflexin 5 -0.0181368
GTF2I general transcription factor IIi -0.0181121
SHLD1 shieldin complex subunit 1 -0.0180217
PPP4R3B protein phosphatase 4 regulatory subunit 3B -0.0180086
MAGED1 melanoma antigen family D1 -0.0179984
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0179722
GTPBP4 GTP binding protein 4 -0.0178548
CDR2 cerebellar degeneration-related protein 2, 62kDa -0.017799
ASXL1 additional sex combs like transcriptional regulator 1 -0.0177892
R3HDM1 R3H domain containing 1 -0.0177681
ICE2 interactor of little elongation complex ELL subunit 2 -0.0176396
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0176199
ATXN2 ataxin 2 -0.0175582
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -0.0175326
UBXN2A UBX domain protein 2A -0.0174247
LAMB1 laminin, beta 1 -0.0174038
PROCR protein C receptor, endothelial -0.0173712
LIMD1 LIM domains containing 1 -0.0173693
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0171306
KDM6A lysine (K)-specific demethylase 6A -0.0170926
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0170907
RPS20 ribosomal protein S20 -0.0170658
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -0.0170598
EXOC6 exocyst complex component 6 -0.0170393
MAML3 mastermind-like 3 (Drosophila) -0.0169387
PDLIM5 PDZ and LIM domain 5 -0.0168708
PLCE1 phospholipase C, epsilon 1 -0.0167597
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 -0.0166696
UNC13B unc-13 homolog B (C. elegans) -0.0165508
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0165452
LRRC23 leucine rich repeat containing 23 -0.0165369
GOLM1 golgi membrane protein 1 -0.0165346
LASP1 LIM and SH3 protein 1 -0.0163904
ERRFI1 ERBB receptor feedback inhibitor 1 -0.01638
CKAP5 cytoskeleton associated protein 5 -0.0163132
CLIP2 CAP-GLY domain containing linker protein 2 -0.0162894
PARD3 par-3 family cell polarity regulator -0.0162526
HELLS helicase, lymphoid-specific -0.0161941
SMYD3 SET and MYND domain containing 3 -0.0161877
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0161174
PHIP pleckstrin homology domain interacting protein -0.015946
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0159185
PIAS1 protein inhibitor of activated STAT, 1 -0.0158709
RDX radixin -0.0158485
CLASRP CLK4-associating serine/arginine rich protein -0.0158371
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -0.0158223
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -0.0158012
SHLD2 shieldin complex subunit 2 -0.0157579
UBN1 ubinuclein 1 -0.0157286
DOCK9 dedicator of cytokinesis 9 -0.0156239
TTC7A tetratricopeptide repeat domain 7A -0.0154188
AVL9 AVL9 homolog (S. cerevisiase) -0.0154153
LMTK2 lemur tyrosine kinase 2 -0.0153444
TMOD3 tropomodulin 3 (ubiquitous) -0.015336
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0153339
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0153089
BSG basigin (Ok blood group) -0.0153038
TBC1D5 TBC1 domain family, member 5 -0.0152853
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0152453
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.0152269
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.0152044
COL4A4 collagen, type IV, alpha 4 -0.0151395
ARHGAP24 Rho GTPase activating protein 24 -0.01513
TFF1 trefoil factor 1 -0.0150985
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.0150776
CTSD cathepsin D -0.0150527
PPP5C protein phosphatase 5, catalytic subunit -0.0150375
ZMYM2 zinc finger, MYM-type 2 -0.015021
UBE3C ubiquitin protein ligase E3C -0.01502
UNK unkempt family zinc finger -0.0150147
ATG5 autophagy related 5 -0.0148943
NOP58 NOP58 ribonucleoprotein -0.0148839
PROS1 protein S (alpha) -0.0148819
IRS2 insulin receptor substrate 2 -0.0148781
PTPRG protein tyrosine phosphatase, receptor type, G -0.0148725
NCOR1 nuclear receptor corepressor 1 -0.0148626
RAD9A RAD9 homolog A (S. pombe) -0.0148558
PLXNA2 plexin A2 -0.0148493
EMP2 epithelial membrane protein 2 -0.0148001
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -0.0147796
ZNF652 zinc finger protein 652 -0.0147452
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0147158
NCKAP5 NCK-associated protein 5 -0.0147108
SPPL2A signal peptide peptidase like 2A -0.0146725
AP1S3 adaptor-related protein complex 1, sigma 3 subunit -0.0146703
ARL15 ADP-ribosylation factor-like 15 -0.0146204
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0145962
TUFM Tu translation elongation factor, mitochondrial -0.01458
TBL1X transducin (beta)-like 1X-linked -0.0144984
DGLUCY D-glutamate cyclase -0.0144922
RHOBTB3 Rho-related BTB domain containing 3 -0.0144822
SMOC1 SPARC related modular calcium binding 1 -0.0144304
NRDC nardilysin convertase -0.0144081
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0143998
SLC25A43 solute carrier family 25, member 43 -0.0143602
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0143459
IWS1 IWS1 homolog (S. cerevisiae) -0.0142703
DENND5A DENN/MADD domain containing 5A -0.0142522
CFH complement factor H -0.0142428
HEATR5B HEAT repeat containing 5B -0.0141926
SLC38A2 solute carrier family 38, member 2 -0.0141889
KIF15 kinesin family member 15 -0.014171
BCAR3 breast cancer anti-estrogen resistance 3 -0.0141472
FCGBP Fc fragment of IgG binding protein -0.0141457
CAND1 cullin-associated and neddylation-dissociated 1 -0.0141281
ZMAT4 zinc finger, matrin-type 4 -0.0141279
PDS5B PDS5 cohesin associated factor B -0.014124
CENPP centromere protein P -0.0140955
INAVA innate immunity activator -0.0140888
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0140791
MED12 mediator complex subunit 12 -0.0140701
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.0140627
CDC50A cell division cycle 50 P4-ATPase accessory subunit A -0.0140579
SRFBP1 serum response factor binding protein 1 -0.0140391
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0139521
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0139508
TTC27 tetratricopeptide repeat domain 27 -0.0139393
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.0139342
SOAT1 sterol O-acyltransferase 1 -0.0138769
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0138664
HDAC8 histone deacetylase 8 -0.0138644
MCFD2 multiple coagulation factor deficiency 2 -0.0138591
CGGBP1 CGG triplet repeat binding protein 1 -0.0138169
TSLIG1 tRNA splicing ligase complex subunit 1 -0.0138057
POTEF POTE ankyrin domain family, member F -0.0137785
TUT4 terminal uridylyl transferase 4 -0.0137726
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.013764
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.0137592
MARCHF6 membrane associated ring-CH-type finger 6 -0.0137363
TBK1 TANK-binding kinase 1 -0.0137146
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0136895
HRNR hornerin -0.0136859
FAM168A family with sequence similarity 168, member A -0.0136785
ATF7IP activating transcription factor 7 interacting protein -0.0136364
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.0136255
LRIF1 ligand dependent nuclear receptor interacting factor 1 -0.0136209
RPH3AL rabphilin 3A-like (without C2 domains) -0.0136158
ACYP2 acylphosphatase 2, muscle type -0.0135943
ACTN4 actinin, alpha 4 -0.0135403
MYO1D myosin ID -0.0135301
CCDC125 coiled-coil domain containing 125 -0.013429
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.0134077
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0133911
SCLT1 sodium channel and clathrin linker 1 -0.0133789
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.0133671
ZZZ3 zinc finger, ZZ-type containing 3 -0.0133666
KNTC1 kinetochore associated 1 -0.0133451
STRN striatin, calmodulin binding protein -0.0133392
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0133083
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -0.0133067
ZFP36L2 ZFP36 ring finger protein-like 2 -0.0133041
EXOC6B exocyst complex component 6B -0.0132962
HOMER2 homer scaffolding protein 2 -0.0132762
TMEM164 transmembrane protein 164 -0.0131161
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.0131089
YY1AP1 YY1 associated protein 1 -0.0130944
MTCL1 microtubule crosslinking factor 1 -0.013091
THSD4 thrombospondin, type I, domain containing 4 -0.0130515
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0130437
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.0129867
VASP vasodilator-stimulated phosphoprotein -0.0129567
CPLX2 complexin 2 -0.0129533
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.0129369
DERA deoxyribose-phosphate aldolase (putative) -0.0129145
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0128963
PHACTR2 phosphatase and actin regulator 2 -0.0128942
ZRANB3 zinc finger, RAN-binding domain containing 3 -0.0128412
TICRR TOPBP1-interacting checkpoint and replication regulator -0.0128228
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0128069
RHBDD1 rhomboid domain containing 1 -0.0127808
SCFD2 sec1 family domain containing 2 -0.0127391
MARK4 MAP/microtubule affinity-regulating kinase 4 -0.0127308
METTL16 methyltransferase like 16 -0.0127245
CSDE1 cold shock domain containing E1, RNA-binding -0.0127244
ATG7 autophagy related 7 -0.0127213
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.0127153
SIDT1 SID1 transmembrane family, member 1 -0.0125968
SHROOM3 shroom family member 3 -0.0125828
CHPT1 choline phosphotransferase 1 -0.0125326
ANKRD44 ankyrin repeat domain 44 -0.0125152
BPTF bromodomain PHD finger transcription factor -0.0125085
SNX1 sorting nexin 1 -0.0124973
CENPB centromere protein B, 80kDa -0.0124434
ATE1 arginyltransferase 1 -0.0124388
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -0.0124369
WDR41 WD repeat domain 41 -0.0124342
PRTG protogenin -0.0123964
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.0123532
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.0123133
RNF111 ring finger protein 111 -0.0122781
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0122769
UBA2 ubiquitin-like modifier activating enzyme 2 -0.0121911
KIF11 kinesin family member 11 -0.0121898
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.0121884
RIC8B RIC8 guanine nucleotide exchange factor B -0.0121859
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -0.0121751
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -0.0121709
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.0121583
LSG1 large 60S subunit nuclear export GTPase 1 -0.012152
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.0121363
PSD3 pleckstrin and Sec7 domain containing 3 -0.0121206
FKBP5 FK506 binding protein 5 -0.0121019
RPL22 ribosomal protein L22 -0.012079
ENOSF1 enolase superfamily member 1 -0.0120627
RIN2 Ras and Rab interactor 2 -0.012054
SAE1 SUMO1 activating enzyme subunit 1 -0.0120499
MEIS2 Meis homeobox 2 -0.0120464
THSD7A thrombospondin, type I, domain containing 7A -0.0120277
PGM2L1 phosphoglucomutase 2-like 1 -0.0119953
CARS1 cysteinyl-tRNA synthetase 1 -0.0119799
PLS3 plastin 3 -0.0119773
INO80 INO80 complex subunit -0.0119495
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0119336
DIAPH3 diaphanous-related formin 3 -0.0119189
FCHO2 FCH domain only 2 -0.0118941
TRAPPC9 trafficking protein particle complex 9 -0.0118826
C2CD3 C2 calcium-dependent domain containing 3 -0.011872
SLC71A2 solute carrier family 71 member 2 -0.01187
RBPMS RNA binding protein with multiple splicing -0.0118695
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -0.0118666
FAM168B family with sequence similarity 168, member B -0.0118589
RASAL2 RAS protein activator like 2 -0.0118571
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -0.0118512
NNMT nicotinamide N-methyltransferase -0.0118348
PTBP2 polypyrimidine tract binding protein 2 -0.0118294
REV1 REV1, polymerase (DNA directed) -0.0118281
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -0.0118239
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -0.0118229
ETNK1 ethanolamine kinase 1 -0.0118182
JUP junction plakoglobin -0.011812
SRPK2 SRSF protein kinase 2 -0.0118022
ZNF644 zinc finger protein 644 -0.0118005
FGG fibrinogen gamma chain -0.011798
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0117879
DNM1 dynamin 1 -0.0117842
KIF3B kinesin family member 3B -0.0117812
GRWD1 glutamate-rich WD repeat containing 1 -0.0117536
GGNBP2 gametogenetin binding protein 2 -0.0117523
CEP128 centrosomal protein 128kDa -0.0117409
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0117367
IL13RA1 interleukin 13 receptor, alpha 1 -0.0117163
MCM4 minichromosome maintenance complex component 4 -0.0117119
INVS inversin -0.0117063
SPICE1 spindle and centriole associated protein 1 -0.011701
FAM13B family with sequence similarity 13, member B -0.0116965
SUFU suppressor of fused homolog (Drosophila) -0.0116912
PHF20 PHD finger protein 20 -0.0116703
MGLL monoglyceride lipase -0.0116597
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.011634
MSRB3 methionine sulfoxide reductase B3 -0.0116281
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0116187
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.0115854
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) -0.0115722
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.0115627
FAT1 FAT atypical cadherin 1 -0.0115575
FOXJ3 forkhead box J3 -0.0115364
TTC6 tetratricopeptide repeat domain 6 -0.0115277
NIPBL Nipped-B homolog (Drosophila) -0.0114993
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0114732
REEP3 receptor accessory protein 3 -0.0114654
HIP1 huntingtin interacting protein 1 -0.011441
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.0114118
ZC2HC1A zinc finger, C2HC-type containing 1A -0.0114067
RBMX RNA binding motif protein, X-linked -0.0113828
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0113786
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -0.011374
SLX4IP SLX4 interacting protein -0.0113113
NBEA neurobeachin -0.0113102
FRY furry homolog (Drosophila) -0.0113069
CALD1 caldesmon 1 -0.0113066
YTHDC2 YTH domain containing 2 -0.0113066
NIPSNAP1 nipsnap homolog 1 (C. elegans) -0.0113019
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -0.0112986
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0112869
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.0112793
MYDGF myeloid-derived growth factor -0.0112762
DUSP4 dual specificity phosphatase 4 -0.0112576
GEN1 GEN1 Holliday junction 5' flap endonuclease -0.0112336
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.0112191
CERS6 ceramide synthase 6 -0.0112183
MBD5 methyl-CpG binding domain protein 5 -0.0112059
S100PBP S100P binding protein -0.0112046
NUP205 nucleoporin 205kDa -0.0111914
SPATS2 spermatogenesis associated, serine-rich 2 -0.011141
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0111383
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.0111363
ATXN3 ataxin 3 -0.0111045
STK24 serine/threonine kinase 24 -0.0110937
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0110925
DYM dymeclin -0.0110441
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -0.0110286
RBL2 retinoblastoma-like 2 -0.0110192
FOXA2 forkhead box A2 -0.0110123
GSE1 Gse1 coiled-coil protein -0.0110105
PRKCSH protein kinase C substrate 80K-H -0.01101
UTP4 UTP4 small subunit processome component -0.0110078
SLC44A1 solute carrier family 44 (choline transporter), member 1 -0.0110006
MOK MOK protein kinase -0.0109921
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0109608
ANO6 anoctamin 6 -0.010946
RB1 retinoblastoma 1 -0.0109299
VCAN versican -0.0109257
TMCC1 transmembrane and coiled-coil domain family 1 -0.0109174
LIN52 lin-52 DREAM MuvB core complex component -0.0109106
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0109048
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.0108976
KANSL2 KAT8 regulatory NSL complex subunit 2 -0.0108634
ERMP1 endoplasmic reticulum metallopeptidase 1 -0.0108615
NBEAL1 neurobeachin-like 1 -0.0108523