A549_SGI-1776 free base_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description SGI-1776 free base 100nM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_SGI-1776 free base_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.201515
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.140023
KRT8 keratin 8, type II 0.13882
FTL ferritin, light polypeptide 0.128138
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.125261
CA12 carbonic anhydrase XII 0.113597
UBL4A ubiquitin-like 4A 0.0989711
AKR1C1 aldo-keto reductase family 1, member C1 0.0882715
AKR1C2 aldo-keto reductase family 1, member C2 0.0773421
GPX2 glutathione peroxidase 2 0.0742841
KRT18 keratin 18, type I 0.0722411
PKM pyruvate kinase, muscle 0.0686017
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0661683
S100A6 S100 calcium binding protein A6 0.0654138
S100A4 S100 calcium binding protein A4 0.0643503
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0573982
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0551372
ACTN4 actinin, alpha 4 0.0547827
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0503883
IGFBP4 insulin-like growth factor binding protein 4 0.0498679
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.048909
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0459277
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.0456353
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0453908
MAP7 microtubule-associated protein 7 0.0443725
PBX1 pre-B-cell leukemia homeobox 1 0.043829
FBXL20 F-box and leucine-rich repeat protein 20 0.0435085
DST dystonin 0.0414933
CD151 CD151 molecule (Raph blood group) 0.0411174
TMSB10 thymosin beta 10 0.0406762
DIAPH2 diaphanous-related formin 2 0.039559
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0384251
CTSD cathepsin D 0.0374606
ABTB3 ankyrin repeat and BTB domain containing 3 0.0374599
MAML3 mastermind-like 3 (Drosophila) 0.0371204
AKR1C3 aldo-keto reductase family 1, member C3 0.0369008
LARP1 La ribonucleoprotein domain family, member 1 0.0365538
AHNAK2 AHNAK nucleoprotein 2 0.0363855
ARHGAP18 Rho GTPase activating protein 18 0.0356473
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0352859
IPO9 importin 9 0.0346392
RSPO3 R-spondin 3 0.0346366
TM4SF1 transmembrane 4 L six family member 1 0.0342935
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0341953
S100A10 S100 calcium binding protein A10 0.0341279
DSTN destrin (actin depolymerizing factor) 0.0338566
MPG N-methylpurine-DNA glycosylase 0.0337202
MYOF myoferlin 0.0335487
KDM2A lysine (K)-specific demethylase 2A 0.0335115
VDAC2 voltage-dependent anion channel 2 0.033136
LPP LIM domain containing preferred translocation partner in lipoma 0.0329317
KRT81 keratin 81, type II 0.0329051
FAF1 Fas (TNFRSF6) associated factor 1 0.0328494
VCP valosin containing protein 0.0321187
RANBP2 RAN binding protein 2 0.0320208
ENO1 enolase 1, (alpha) 0.0316917
CAPNS1 calpain, small subunit 1 0.0315759
VIM vimentin 0.0312586
CUEDC1 CUE domain containing 1 0.0311807
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0310099
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0309526
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0307676
ACACA acetyl-CoA carboxylase alpha 0.0304249
RPLP0 ribosomal protein, large, P0 0.0301009
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 0.0300639
POTEF POTE ankyrin domain family, member F 0.0299784
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0298623
GLIS3 GLIS family zinc finger 3 0.0296958
EFNA5 ephrin-A5 0.0294041
CPLX2 complexin 2 0.0293634
NRCAM neuronal cell adhesion molecule 0.0292174
PLEC plectin 0.0290437
TPM3 tropomyosin 3 0.0289845
RPL37 ribosomal protein L37 0.0287751
RPS23 ribosomal protein S23 0.0286793
UBB ubiquitin B 0.02816
BMPR1A bone morphogenetic protein receptor, type IA 0.0280536
CAPN2 calpain 2, (m/II) large subunit 0.0280123
BRCA1 breast cancer 1, early onset 0.0279578
EMC10 ER membrane protein complex subunit 10 0.0279338
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.0277623
TTC17 tetratricopeptide repeat domain 17 0.0276128
CLASP1 cytoplasmic linker associated protein 1 0.0275331
IQGAP1 IQ motif containing GTPase activating protein 1 0.0275125
MORC4 MORC family CW-type zinc finger 4 0.0272396
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0271765
RPS19 ribosomal protein S19 0.0270203
KTN1 kinectin 1 (kinesin receptor) 0.0269512
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.0268811
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0267346
MRPL13 mitochondrial ribosomal protein L13 0.0265098
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.026276
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.0262096
SBF2 SET binding factor 2 0.0261092
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.026007
RPL35 ribosomal protein L35 0.025966
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0259526
TRIM33 tripartite motif containing 33 0.0258285
HSPB1 heat shock 27kDa protein 1 0.0257762
PTK2 protein tyrosine kinase 2 0.025675
CNST consortin, connexin sorting protein 0.0256173
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.0255838
DPYD dihydropyrimidine dehydrogenase 0.0254711
ITM2B integral membrane protein 2B 0.0253105
SNX5 sorting nexin 5 0.0249467
UBE2H ubiquitin-conjugating enzyme E2H 0.0248897
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0247951
SHTN1 shootin 1 0.0246922
SLC35F3 solute carrier family 35, member F3 0.0244069
CD81 CD81 molecule 0.0241455
RAD51B RAD51 paralog B 0.0240978
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.0239092
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0239041
VEZT vezatin, adherens junctions transmembrane protein 0.0236732
ATP5F1B ATP synthase F1 subunit beta 0.0235933
UBE4B ubiquitination factor E4B 0.0235069
FADS2 fatty acid desaturase 2 0.0233381
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0232117
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0230662
RPL13A ribosomal protein L13a 0.0230593
GRB10 growth factor receptor-bound protein 10 0.0229527
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0229224
MTDH metadherin 0.0228817
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.022836
TPI1 triosephosphate isomerase 1 0.0227428
SFT2D2 SFT2 domain containing 2 0.0224951
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0224478
LDHA lactate dehydrogenase A 0.0224064
SSH2 slingshot protein phosphatase 2 0.0223773
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.022346
RABAC1 Rab acceptor 1 (prenylated) 0.0223386
PRSS3 protease, serine, 3 0.0223366
GPATCH8 G patch domain containing 8 0.0223166
CD44 CD44 molecule (Indian blood group) 0.0220795
PSD3 pleckstrin and Sec7 domain containing 3 0.0220297
TP53I3 tumor protein p53 inducible protein 3 0.0219697
BSG basigin (Ok blood group) 0.0218976
ADNP activity-dependent neuroprotector homeobox 0.0218877
PHF14 PHD finger protein 14 0.0218236
NOL10 nucleolar protein 10 0.0217236
REEP3 receptor accessory protein 3 0.0216886
VDAC1 voltage-dependent anion channel 1 0.021682
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0216283
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.0215992
MGST1 microsomal glutathione S-transferase 1 0.0215989
SUGP2 SURP and G patch domain containing 2 0.0215842
RPL10A ribosomal protein L10a 0.0214638
FBXO11 F-box protein 11 0.0214574
LOC112694756 uncharaterized LOC112694756 0.0214219
CORO1B coronin, actin binding protein, 1B 0.0214083
MMS22L MMS22-like, DNA repair protein 0.0213469
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0212802
ACTN1 actinin, alpha 1 0.0212596
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.0211753
ABHD2 abhydrolase domain containing 2 0.0211199
ATAD2 ATPase family, AAA domain containing 2 0.0210569
GTF2I general transcription factor IIi 0.021056
NUDC nudC nuclear distribution protein 0.0208871
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.02088
ATXN7L1 ataxin 7-like 1 0.020849
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0208389
SUMO2 small ubiquitin-like modifier 2 0.0206367
ZFP36L2 ZFP36 ring finger protein-like 2 0.0206139
DHCR24 24-dehydrocholesterol reductase 0.0205966
SH3KBP1 SH3-domain kinase binding protein 1 0.0204993
RPLP2 ribosomal protein, large, P2 0.0204959
CLIP1 CAP-GLY domain containing linker protein 1 0.0204821
PTPRG protein tyrosine phosphatase, receptor type, G 0.0204475
ACLY ATP citrate lyase 0.020251
RDX radixin 0.0202406
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0199788
CDYL chromodomain protein, Y-like 0.0199766
NUP210 nucleoporin 210kDa 0.0199567
DSPP dentin sialophosphoprotein 0.0199046
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0197247
NUP35 nucleoporin 35kDa 0.0197206
NCOA3 nuclear receptor coactivator 3 0.019691
TIMP1 TIMP metallopeptidase inhibitor 1 0.0196684
DTX2 deltex 2, E3 ubiquitin ligase 0.0196476
TUFM Tu translation elongation factor, mitochondrial 0.0196054
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0195866
ERMP1 endoplasmic reticulum metallopeptidase 1 0.0195183
KDM2B lysine (K)-specific demethylase 2B 0.0194049
CNTLN centlein, centrosomal protein 0.0193162
VCAN versican 0.0193149
UGP2 UDP-glucose pyrophosphorylase 2 0.0192421
TTC3 tetratricopeptide repeat domain 3 0.0192135
SREBF1 sterol regulatory element binding transcription factor 1 0.0191925
AGR2 anterior gradient 2 0.0191361
RBBP7 retinoblastoma binding protein 7 0.0191224
PDZD8 PDZ domain containing 8 0.0191108
STRBP spermatid perinuclear RNA binding protein 0.0190915
TSC22D1 TSC22 domain family, member 1 0.0190874
EGFR epidermal growth factor receptor 0.0189892
HIPK2 homeodomain interacting protein kinase 2 0.018961
TRIM28 tripartite motif containing 28 0.0189108
CANX calnexin 0.0188892
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 0.0188507
HPS5 Hermansky-Pudlak syndrome 5 0.0188202
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.0188201
LRP10 low density lipoprotein receptor-related protein 10 0.0188128
PFN1 profilin 1 0.0187864
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.0187628
ALG3 ALG3, alpha-1,3- mannosyltransferase 0.0187627
COG8 component of oligomeric golgi complex 8 0.0187548
CLSPN claspin 0.0187495
LDAH lipid droplet associated hydrolase 0.0186314
RHOA ras homolog family member A 0.0186258
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0186151
SYTL2 synaptotagmin-like 2 0.0186113
CRTAP cartilage associated protein 0.0186105
ANXA4 annexin A4 0.0186034
SH3PXD2A SH3 and PX domains 2A 0.0184902
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0184564
TPR translocated promoter region, nuclear basket protein 0.0184337
NIPSNAP2 nipsnap homolog 2 0.0183423
CENPP centromere protein P 0.0183422
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0183322
STAG2 stromal antigen 2 0.0183279
SPAG1 sperm associated antigen 1 0.0183116
TBCK TBC1 domain containing kinase 0.0182119
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.0181732
FANCI Fanconi anemia, complementation group I 0.0181669
AGO2 argonaute RISC catalytic component 2 0.018155
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.0180757
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.0180362
SMIM44 small integral membrane protein 44 0.0180267
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0179985
ERBIN erbb2 interacting protein 0.0179978
STMN1 stathmin 1 0.0179977
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 0.0179576
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0179184
EIPR1 EARP complex and GARP complex interacting protein 1 0.0178569
ALCAM activated leukocyte cell adhesion molecule 0.0177721
SND1 staphylococcal nuclease and tudor domain containing 1 0.0177545
LRRC23 leucine rich repeat containing 23 0.0177502
PRMT3 protein arginine methyltransferase 3 0.017722
DARS1 aspartyl-tRNA synthetase 1 0.0176809
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.0176747
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0176692
PDCD10 programmed cell death 10 0.0176437
H3-3B H3.3 histone B 0.0176394
SELENOF selenoprotein F 0.0176069
LURAP1L leucine rich adaptor protein 1-like 0.017566
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.0175062
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0174996
ASXL2 additional sex combs like transcriptional regulator 2 0.0174599
RPS27A ribosomal protein S27a 0.0174415
JUP junction plakoglobin 0.0174408
RPL4 ribosomal protein L4 0.0174408
NMT1 N-myristoyltransferase 1 0.0173768
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.0173739
TSKU tsukushi, small leucine rich proteoglycan 0.0173615
LRP1B low density lipoprotein receptor-related protein 1B 0.0173449
DNA2 DNA replication helicase/nuclease 2 0.0172893
KIF21A kinesin family member 21A 0.0172807
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.0172443
GPR75-ASB3 GPR75-ASB3 readthrough 0.0172398
PTPRK protein tyrosine phosphatase, receptor type, K 0.0172295
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.0172119
RUNDC1 RUN domain containing 1 0.0171885
INTS7 integrator complex subunit 7 0.0171526
KPNB1 karyopherin (importin) beta 1 0.0170393
STAU1 staufen double-stranded RNA binding protein 1 0.0170279
APP amyloid beta (A4) precursor protein 0.0170155
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.0169509
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0168999
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0168909
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0167828
BIRC5 baculoviral IAP repeat containing 5 0.0167821
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.0167493
RPL8 ribosomal protein L8 0.0167249
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.0165273
BICDL1 BICD family like cargo adaptor 1 0.0165246
MTX2 metaxin 2 0.0165199
DNAH14 dynein, axonemal, heavy chain 14 0.016515
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0165076
RNF217 ring finger protein 217 0.0164989
MYEOV myeloma overexpressed 0.0164632
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.0164572
HMGA1 high mobility group AT-hook 1 0.016443
GATAD2B GATA zinc finger domain containing 2B 0.0164236
PA2G4 proliferation-associated 2G4, 38kDa 0.0164074
ELP4 elongator acetyltransferase complex subunit 4 0.0163985
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 0.0162942
KCTD1 potassium channel tetramerization domain containing 1 0.0162936
RBM33 RNA binding motif protein 33 0.0161942
TMPO thymopoietin 0.0161831
EXOC4 exocyst complex component 4 0.0161522
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 0.0159932
OAZ1 ornithine decarboxylase antizyme 1 0.0159606
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0159226
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.0158965
MPDU1 mannose-P-dolichol utilization defect 1 0.0158939
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.015885
CD109 CD109 molecule 0.0158661
PLD3 phospholipase D family, member 3 0.0158615
OSBPL1A oxysterol binding protein-like 1A 0.0158587
AKT1S1 AKT1 substrate 1 (proline-rich) 0.0158329
RPSA ribosomal protein SA 0.0158163
IREB2 iron-responsive element binding protein 2 0.0157568
CBR1 carbonyl reductase 1 0.0157361
SPAST spastin 0.0157215
CST1 cystatin SN 0.0156993
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0156824
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0156579
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.0156331
CTCF CCCTC-binding factor (zinc finger protein) 0.0155959
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0155756
RLF rearranged L-myc fusion 0.0155348
RPL5 ribosomal protein L5 0.0155161
SPPL2A signal peptide peptidase like 2A 0.0154916
CMIP c-Maf inducing protein 0.0154773
TWIST2 twist family bHLH transcription factor 2 0.0154376
RPS8 ribosomal protein S8 0.0154165
ELOVL6 ELOVL fatty acid elongase 6 0.0154088
XYLB xylulokinase homolog (H. influenzae) 0.0153229
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.0153162
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.015309
TSPAN14 tetraspanin 14 0.0152622
TCERG1 transcription elongation regulator 1 0.0152537
MSH6 mutS homolog 6 0.0152223
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 0.0151238
SCAPER S-phase cyclin A-associated protein in the ER 0.0151234
EEF2 eukaryotic translation elongation factor 2 0.0151089
ZBTB4 zinc finger and BTB domain containing 4 0.0151048
MAST2 microtubule associated serine/threonine kinase 2 0.015074
RPS24 ribosomal protein S24 0.0150727
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0150659
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0150062
CCND3 cyclin D3 0.0150016
FTH1 ferritin, heavy polypeptide 1 0.0149955
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.0149706
TMEM164 transmembrane protein 164 0.014941
RNF216 ring finger protein 216 0.0149257
ERCC6L2 excision repair cross-complementation group 6-like 2 0.0149177
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.0149151
CCDC137 coiled-coil domain containing 137 0.0149098
MBNL1 muscleblind-like splicing regulator 1 0.0149067
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0148942
PLBD2 phospholipase B domain containing 2 0.0148675
WASF2 WAS protein family, member 2 0.0148562
EXT2 exostosin glycosyltransferase 2 0.0148274
AUP1 ancient ubiquitous protein 1 0.0148037
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.014801
HELLS helicase, lymphoid-specific 0.01479
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 0.0147777
SSBP3 single stranded DNA binding protein 3 0.0147621
ITGAV integrin, alpha V 0.0147502
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.0147375
DMWD dystrophia myotonica, WD repeat containing 0.0147125
GREB1 growth regulation by estrogen in breast cancer 1 0.0146939
THSD7A thrombospondin, type I, domain containing 7A 0.0146171
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0145923
RECQL RecQ helicase-like 0.0145532
DOCK3 dedicator of cytokinesis 3 0.0145035
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0145022
MIS18BP1 MIS18 binding protein 1 0.0144992
NXPE3 neurexophilin and PC-esterase domain family, member 3 0.0144924
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0144582
METTL8 methyltransferase like 8 0.0144569
ZFP36L1 ZFP36 ring finger protein-like 1 0.0144568
C1RL complement component 1, r subcomponent-like 0.0144541
TMEM44 transmembrane protein 44 0.0144246
RPS6 ribosomal protein S6 0.0144097
MCMBP minichromosome maintenance complex binding protein 0.0144059
FBXO17 F-box protein 17 0.0143992
IL6ST interleukin 6 signal transducer 0.0143802
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.0143381
CDK12 cyclin-dependent kinase 12 0.0143208
SAP130 Sin3A-associated protein, 130kDa 0.0142993
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.0142852
RPL15 ribosomal protein L15 0.0142631
CEP55 centrosomal protein 55kDa 0.014263
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0142609
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0141937
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.0141759
CUL2 cullin 2 0.0141737
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0141505
KAT6A K(lysine) acetyltransferase 6A 0.014147
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0141282
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.0141259
MFSD12 major facilitator superfamily domain containing 12 0.014107
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0140989
PHKB phosphorylase kinase, beta 0.0140929
CHD6 chromodomain helicase DNA binding protein 6 0.0140907
LARP1B La ribonucleoprotein domain family, member 1B 0.0140366
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.0140131
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.014012
RAI14 retinoic acid induced 14 0.0140084
C1QBP complement component 1, q subcomponent binding protein 0.0139912
MACROD2 MACRO domain containing 2 0.0139824
CLTC clathrin, heavy chain (Hc) 0.0139723
METTL15 methyltransferase like 15 0.0139711
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0139558
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0139541
STAU2 staufen double-stranded RNA binding protein 2 0.0139315
CAV1 caveolin 1, caveolae protein, 22kDa 0.013915
LRRC75A leucine rich repeat containing 75A 0.0138934
DNM1L dynamin 1-like 0.0138779
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0138768
MCFD2 multiple coagulation factor deficiency 2 0.0138733
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.0138632
NONO non-POU domain containing, octamer-binding 0.0138107
NT5DC3 5'-nucleotidase domain containing 3 0.0138092
CANT1 calcium activated nucleotidase 1 0.0138036
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0137945
USP40 ubiquitin specific peptidase 40 0.0137684
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0137488
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0137281
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.0136832
SFTPA2 surfactant protein A2 0.0136721
NSD2 nuclear receptor binding SET domain protein 2 0.0136719
NEK8 NIMA-related kinase 8 0.0136662
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.0136413
CSNK1D casein kinase 1, delta 0.0136398
ZEB1 zinc finger E-box binding homeobox 1 0.013628
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.0136238
NUP62 nucleoporin 62kDa 0.0136132
ACOT7 acyl-CoA thioesterase 7 0.0136114
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.0136078
GPS2 G protein pathway suppressor 2 0.0135688
C1ORF122 chromosome 1 open reading frame 122 0.0135099
NHLRC2 NHL repeat containing 2 0.0135057
SCAMP3 secretory carrier membrane protein 3 0.0134699
SLPI secretory leukocyte peptidase inhibitor 0.0134594
MAP7D2 MAP7 domain containing 2 0.0134258
FKBP11 FK506 binding protein 11, 19 kDa 0.0134049
BLTP2 bridge-like lipid transfer protein family member 2 0.0133972
LASP1 LIM and SH3 protein 1 0.0133875
PPCDC phosphopantothenoylcysteine decarboxylase 0.0133784
KEAP1 kelch-like ECH-associated protein 1 0.0133664
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.0133281
LY6E lymphocyte antigen 6 complex, locus E 0.0133095
DCAF7 DDB1 and CUL4 associated factor 7 0.013269
LAMA5 laminin, alpha 5 0.0132676
ABHD12 abhydrolase domain containing 12 0.0132454
ACSF3 acyl-CoA synthetase family member 3 0.0132389
RPL32 ribosomal protein L32 0.0132298
CNN3 calponin 3, acidic 0.0132276
P3H1 prolyl 3-hydroxylase 1 0.0132067
KIAA1958 KIAA1958 0.0131793
SLIT3 slit homolog 3 (Drosophila) 0.0131519
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.0131389
LIN54 lin-54 DREAM MuvB core complex component 0.0131348
OXSR1 oxidative stress responsive 1 0.0131343
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0131205
PTPRM protein tyrosine phosphatase, receptor type, M 0.0131181
CLCN5 chloride channel, voltage-sensitive 5 0.0131112
BTBD9 BTB (POZ) domain containing 9 0.0130875
CASD1 CAS1 domain containing 1 0.0130565
BBX bobby sox homolog (Drosophila) 0.0130352
CYRIB CYFIP related Rac1 interactor B 0.0130249
MSI2 musashi RNA-binding protein 2 0.0129839
STK35 serine/threonine kinase 35 0.0129746
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 0.012967
LRRC59 leucine rich repeat containing 59 0.0129625
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.0129598
CMC2 C-x(9)-C motif containing 2 0.0129048
CORO1C coronin, actin binding protein, 1C 0.0129018
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.0128996
BCAS1 breast carcinoma amplified sequence 1 0.0128939
TACR1 tachykinin receptor 1 0.0128786
TTC7A tetratricopeptide repeat domain 7A 0.0128741
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.0128691
RPS2 ribosomal protein S2 0.0128641
SYT17 synaptotagmin XVII 0.0128619
TASP1 taspase, threonine aspartase, 1 0.0128599
TCEA1 transcription elongation factor A (SII), 1 0.0128462
LAMB1 laminin, beta 1 0.012845
RFWD3 ring finger and WD repeat domain 3 0.0128443
TLK2 tousled-like kinase 2 0.0128408
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0128381
MSRB3 methionine sulfoxide reductase B3 0.0128374
FBXL5 F-box and leucine-rich repeat protein 5 0.0127899
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0127824
TRIR telomerase RNA component interacting RNase 0.0127622
RPGRIP1L RPGRIP1-like 0.0127593
WAPL WAPL cohesin release factor 0.0127451
SANBR SANT and BTB domain regulator of CSR 0.0127418
IER5L immediate early response 5-like 0.012728
LIFR leukemia inhibitory factor receptor alpha 0.0127168
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.0126806
CFAP44 cilia and flagella associated protein 44 0.0126685
HPCAL1 hippocalcin-like 1 0.0126537
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.0126232
RPS4X ribosomal protein S4, X-linked 0.0126213
NKIRAS2 NFKB inhibitor interacting Ras-like 2 0.0126054
TPM1 tropomyosin 1 (alpha) 0.0125915
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.0125891
MRPS33 mitochondrial ribosomal protein S33 0.0125858
ATF6 activating transcription factor 6 0.0125809
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.0125701
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 0.0125695
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.0125619
KLF12 Kruppel-like factor 12 0.0125341
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.0125089
MYDGF myeloid-derived growth factor 0.0125067
RPL28 ribosomal protein L28 0.0125056
CENPN centromere protein N 0.0124976

decreased expression

Symbol Name Standardized Value
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.118913
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.089196
PDE4D phosphodiesterase 4D, cAMP-specific -0.0852295
ZBTB20 zinc finger and BTB domain containing 20 -0.0806373
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0790925
CUX1 cut-like homeobox 1 -0.0763307
VMP1 vacuole membrane protein 1 -0.0709666
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0695948
CNTNAP3B contactin associated protein-like 3B -0.0657303
FN1 fibronectin 1 -0.0637522
MYO1E myosin IE -0.0592576
WWOX WW domain containing oxidoreductase -0.0588066
FAM107B family with sequence similarity 107, member B -0.0580795
ARL15 ADP-ribosylation factor-like 15 -0.0572936
KYNU kynureninase -0.0550209
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0541191
CLU clusterin -0.0540703
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0503
FNDC3B fibronectin type III domain containing 3B -0.0502643
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0501981
DENND5B DENN/MADD domain containing 5B -0.0501422
ZNF609 zinc finger protein 609 -0.0496038
TPM4 tropomyosin 4 -0.0487725
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0484521
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0481674
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0477978
PTGR1 prostaglandin reductase 1 -0.0470721
MTUS1 microtubule associated tumor suppressor 1 -0.0459655
AOPEP aminopeptidase O (putative) -0.0457827
MYO1D myosin ID -0.0442373
MCU mitochondrial calcium uniporter -0.0441262
ITGB5 integrin, beta 5 -0.0433452
FOXK1 forkhead box K1 -0.0433375
CDK13 cyclin-dependent kinase 13 -0.0430779
IPO7 importin 7 -0.042847
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0428103
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0425785
ARHGAP12 Rho GTPase activating protein 12 -0.042241
SMAD2 SMAD family member 2 -0.0412105
PDE8A phosphodiesterase 8A -0.0409211
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0407041
CNTN1 contactin 1 -0.0407009
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0398049
BMPR1B bone morphogenetic protein receptor, type IB -0.0398029
GCLM glutamate-cysteine ligase, modifier subunit -0.0392741
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0390654
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0383249
BPTF bromodomain PHD finger transcription factor -0.0382166
PDE7B phosphodiesterase 7B -0.0379941
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0379031
PDE10A phosphodiesterase 10A -0.0376463
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0376104
MSH3 mutS homolog 3 -0.0372116
USP34 ubiquitin specific peptidase 34 -0.0368943
FILIP1 filamin A interacting protein 1 -0.0367885
TMOD3 tropomodulin 3 (ubiquitous) -0.0360004
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0356126
SERINC5 serine incorporator 5 -0.0353587
GRAMD1A GRAM domain containing 1A -0.0348218
BIRC6 baculoviral IAP repeat containing 6 -0.0347474
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0343506
SYT1 synaptotagmin I -0.0343498
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0342968
GPRIN3 GPRIN family member 3 -0.034287
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0342666
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0340881
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.0331725
HDAC8 histone deacetylase 8 -0.0331083
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0329567
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0329232
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0328856
RASAL2 RAS protein activator like 2 -0.0324779
ZFHX3 zinc finger homeobox 3 -0.0324746
SMYD3 SET and MYND domain containing 3 -0.0322539
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0320884
USP9X ubiquitin specific peptidase 9, X-linked -0.0320824
STX8 syntaxin 8 -0.0320343
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0320087
GOLM1 golgi membrane protein 1 -0.0319665
TXNRD1 thioredoxin reductase 1 -0.0319023
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0318498
GTF2IRD1 GTF2I repeat domain containing 1 -0.0313252
PCED1B PC-esterase domain containing 1B -0.0311356
FLNB filamin B, beta -0.03104
DENND1A DENN/MADD domain containing 1A -0.0308993
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0307034
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0306808
METTL16 methyltransferase like 16 -0.0306539
NRG1 neuregulin 1 -0.0304559
SRRM2 serine/arginine repetitive matrix 2 -0.0303828
NBEA neurobeachin -0.030176
SEPTIN9 septin 9 -0.0301047
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.029738
TMCC1 transmembrane and coiled-coil domain family 1 -0.0296835
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0296143
PIAS1 protein inhibitor of activated STAT, 1 -0.0295939
UBASH3B ubiquitin associated and SH3 domain containing B -0.0291314
AAK1 AP2 associated kinase 1 -0.0289145
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0287122
SLC39A11 solute carrier family 39, member 11 -0.0285491
AUTS2 autism susceptibility candidate 2 -0.0281975
ZFAND6 zinc finger, AN1-type domain 6 -0.0281534
UTRN utrophin -0.0281334
FOXP1 forkhead box P1 -0.028095
LIMD1 LIM domains containing 1 -0.0280902
SH2D4A SH2 domain containing 4A -0.0280454
MED13L mediator complex subunit 13-like -0.0280087
MED27 mediator complex subunit 27 -0.0279922
RIN2 Ras and Rab interactor 2 -0.0278164
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 -0.0277656
AGFG1 ArfGAP with FG repeats 1 -0.0277653
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0277321
KMT5B lysine methyltransferase 5B -0.0275862
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.027501
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.0273108
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0272831
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0272435
PHF21A PHD finger protein 21A -0.0272357
EPN2 epsin 2 -0.0271303
TJP1 tight junction protein 1 -0.0270621
DAPK1 death-associated protein kinase 1 -0.0269389
HSPA4 heat shock 70kDa protein 4 -0.0268891
AKAP12 A kinase (PRKA) anchor protein 12 -0.0268306
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0267837
TRAPPC12 trafficking protein particle complex 12 -0.0267758
CDC27 cell division cycle 27 -0.0267627
XPO1 exportin 1 -0.0267234
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.026625
RNF145 ring finger protein 145 -0.0265701
ATE1 arginyltransferase 1 -0.026524
SPIDR scaffolding protein involved in DNA repair -0.026356
DIS3L DIS3 like exosome 3'-5' exoribonuclease -0.0263054
PTCD3 pentatricopeptide repeat domain 3 -0.0261254
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.0261031
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -0.0261002
AFF1 AF4/FMR2 family, member 1 -0.0259811
TNPO1 transportin 1 -0.0259185
PHF20 PHD finger protein 20 -0.0259046
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0257749
SEPTIN6 septin 6 -0.025568
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0254519
TNRC6B trinucleotide repeat containing 6B -0.0253658
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.0249173
RBL2 retinoblastoma-like 2 -0.0248851
R3HDM1 R3H domain containing 1 -0.0247265
SESTD1 SEC14 and spectrin domains 1 -0.024649
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.0246238
NFIA nuclear factor I/A -0.0246162
MYO1B myosin IB -0.0245728
KATNBL1 katanin p80 subunit B-like 1 -0.024441
BABAM2 BRISC and BRCA1 A complex member 2 -0.0244303
TNRC6A trinucleotide repeat containing 6A -0.0243538
FANCC Fanconi anemia, complementation group C -0.0241753
PSEN1 presenilin 1 -0.0241491
FBXO42 F-box protein 42 -0.0240828
UBA2 ubiquitin-like modifier activating enzyme 2 -0.02405
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0239294
RBM39 RNA binding motif protein 39 -0.0239099
FAM177A1 family with sequence similarity 177, member A1 -0.0239067
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.023863
KIAA0319 KIAA0319 -0.0236444
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0236252
ZFAND3 zinc finger, AN1-type domain 3 -0.0236252
SDCCAG8 serologically defined colon cancer antigen 8 -0.0236039
BASP1 brain abundant, membrane attached signal protein 1 -0.0235392
NAMPT nicotinamide phosphoribosyltransferase -0.023248
TMEM117 transmembrane protein 117 -0.0230998
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0230681
SIN3A SIN3 transcription regulator family member A -0.0229963
CCDC57 coiled-coil domain containing 57 -0.0229333
PKP4 plakophilin 4 -0.0228465
PDIA3 protein disulfide isomerase family A, member 3 -0.0227961
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0227796
POLK polymerase (DNA directed) kappa -0.0227382
CDKL5 cyclin-dependent kinase-like 5 -0.022698
PAWR PRKC, apoptosis, WT1, regulator -0.0226837
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0226781
THOC2 THO complex 2 -0.022564
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0225577
PHKA2 phosphorylase kinase, alpha 2 (liver) -0.0225429
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0225107
SP3 Sp3 transcription factor -0.0224959
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -0.0224866
GPHN gephyrin -0.022482
CDK17 cyclin-dependent kinase 17 -0.0224675
TBC1D5 TBC1 domain family, member 5 -0.0224066
BCL2L1 BCL2-like 1 -0.0223339
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.0222966
DCP1A decapping mRNA 1A -0.0222152
RTN3 reticulon 3 -0.0222103
RBM47 RNA binding motif protein 47 -0.0222075
DCAKD dephospho-CoA kinase domain containing -0.0220906
SETD5 SET domain containing 5 -0.0220806
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0220375
CBX5 chromobox homolog 5 -0.0219183
ZNF280D zinc finger protein 280D -0.02183
PUM2 pumilio RNA-binding family member 2 -0.0218156
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.0218045
ACBD6 acyl-CoA binding domain containing 6 -0.0217025
PCDH9 protocadherin 9 -0.0216255
RBPMS RNA binding protein with multiple splicing -0.0216112
TMEM184B transmembrane protein 184B -0.0215592
TPX2 TPX2, microtubule-associated -0.0214904
PDE4B phosphodiesterase 4B, cAMP-specific -0.0214716
ATG7 autophagy related 7 -0.021439
DOCK1 dedicator of cytokinesis 1 -0.0214167
ITGA6 integrin, alpha 6 -0.0213373
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0213327
ITCH itchy E3 ubiquitin protein ligase -0.0213234
INVS inversin -0.0212909
LPIN1 lipin 1 -0.0212764
UBE2O ubiquitin-conjugating enzyme E2O -0.021239
SKIL SKI-like proto-oncogene -0.0212087
PLAUR plasminogen activator, urokinase receptor -0.0210678
VASP vasodilator-stimulated phosphoprotein -0.0210496
FBXO28 F-box protein 28 -0.021032
EYA4 EYA transcriptional coactivator and phosphatase 4 -0.0209996
SHLD1 shieldin complex subunit 1 -0.0209961
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0209582
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0209342
SQSTM1 sequestosome 1 -0.0208879
TRAPPC8 trafficking protein particle complex 8 -0.0208495
USP36 ubiquitin specific peptidase 36 -0.0208094
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0207783
ARF4 ADP-ribosylation factor 4 -0.0207708
GLG1 golgi glycoprotein 1 -0.0207668
MORF4L2 mortality factor 4 like 2 -0.0207482
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.0207429
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -0.0207109
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.020666
CKAP5 cytoskeleton associated protein 5 -0.0206335
RRBP1 ribosome binding protein 1 -0.0206029
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.0205291
KAT6B K(lysine) acetyltransferase 6B -0.0204961
KRT7 keratin 7, type II -0.020455
MKI67 marker of proliferation Ki-67 -0.0204478
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0203419
NECTIN2 nectin cell adhesion molecule 2 -0.0203262
NCOA7 nuclear receptor coactivator 7 -0.0202903
MYO5A myosin VA (heavy chain 12, myoxin) -0.0202681
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.0202437
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.0202427
NINL ninein-like -0.0202234
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0200985
FHL2 four and a half LIM domains 2 -0.020092
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0200724
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0199929
NSD3 nuclear receptor binding SET domain protein 3 -0.0199825
RAD21 RAD21 homolog (S. pombe) -0.0199707
ANTXR1 anthrax toxin receptor 1 -0.0199609
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -0.0199595
KDM5B lysine (K)-specific demethylase 5B -0.0199472
RPL37A ribosomal protein L37a -0.0198679
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0198187
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0198075
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -0.0198026
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0197817
EML4 echinoderm microtubule associated protein like 4 -0.0197452
PRPF3 pre-mRNA processing factor 3 -0.0197158
MUSK muscle, skeletal, receptor tyrosine kinase -0.0196966
IKBIP IKBKB interacting protein -0.0196511
IRS2 insulin receptor substrate 2 -0.0196339
PDIA4 protein disulfide isomerase family A, member 4 -0.0196059
PRKCSH protein kinase C substrate 80K-H -0.0195609
ANKRD11 ankyrin repeat domain 11 -0.019281
ZZZ3 zinc finger, ZZ-type containing 3 -0.0192796
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0192094
FGB fibrinogen beta chain -0.0191498
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0190892
SIK3 SIK family kinase 3 -0.0190858
EHBP1 EH domain binding protein 1 -0.0190625
PIR pirin (iron-binding nuclear protein) -0.019054
QSER1 glutamine and serine rich 1 -0.019013
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0190109
ZNRF3 zinc and ring finger 3 -0.0189556
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0189298
ZNF618 zinc finger protein 618 -0.0189169
ZFP64 ZFP64 zinc finger protein -0.018888
PRTG protogenin -0.0188421
PFKP phosphofructokinase, platelet -0.0188375
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0188062
CDK19 cyclin-dependent kinase 19 -0.0187739
SEC23A Sec23 homolog A (S. cerevisiae) -0.0186303
MYH10 myosin, heavy chain 10, non-muscle -0.0185993
SEC31A SEC31 homolog A (S. cerevisiae) -0.0185843
NEBL nebulette -0.0185752
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0184257
PARD3B par-3 family cell polarity regulator beta -0.0183521
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.0183054
RAB1A RAB1A, member RAS oncogene family -0.0182988
CERT1 ceramide transporter 1 -0.0182828
R3HDM2 R3H domain containing 2 -0.0182802
DUSP16 dual specificity phosphatase 16 -0.0182765
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -0.0182646
LMNA lamin A/C -0.0182448
TBCA tubulin folding cofactor A -0.0182187
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.0182044
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -0.0181842
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.0181246
JADE1 jade family PHD finger 1 -0.018098
PER2 period circadian clock 2 -0.0180266
SRPK2 SRSF protein kinase 2 -0.0179706
TPD52 tumor protein D52 -0.017902
PON3 paraoxonase 3 -0.0178938
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.017868
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0178537
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0178185
TBL1X transducin (beta)-like 1X-linked -0.0177981
OLA1 Obg-like ATPase 1 -0.0177978
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -0.0176944
BRD4 bromodomain containing 4 -0.0176805
CNTNAP3 contactin associated protein-like 3 -0.017675
MED29 mediator complex subunit 29 -0.0176599
PLCB4 phospholipase C, beta 4 -0.0175567
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0175425
ITSN2 intersectin 2 -0.0175392
UGDH UDP-glucose 6-dehydrogenase -0.01753
RANBP10 RAN binding protein 10 -0.017488
PRKCA protein kinase C, alpha -0.0174622
APTX aprataxin -0.0174573
RAB6A RAB6A, member RAS oncogene family -0.0174364
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.01741
CAMK2D calcium/calmodulin-dependent protein kinase II delta -0.0173973
NSD1 nuclear receptor binding SET domain protein 1 -0.0173612
SPATA6L spermatogenesis associated 6-like -0.0173421
ADCY9 adenylate cyclase 9 -0.0172805
ICE2 interactor of little elongation complex ELL subunit 2 -0.0172627
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.0172138
SFSWAP splicing factor, suppressor of white-apricot family -0.017181
SCAI suppressor of cancer cell invasion -0.0171604
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0171588
MCM8 minichromosome maintenance complex component 8 -0.0171108
ACER3 alkaline ceramidase 3 -0.0170905
UBTF upstream binding transcription factor, RNA polymerase I -0.0170833
RBM6 RNA binding motif protein 6 -0.017059
THRB thyroid hormone receptor, beta -0.0170586
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0170452
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0170219
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0170086
RABEPK Rab9 effector protein with kelch motifs -0.0169924
FCHSD2 FCH and double SH3 domains 2 -0.0169902
ARHGAP26 Rho GTPase activating protein 26 -0.0169626
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0169011
NR2C1 nuclear receptor subfamily 2, group C, member 1 -0.0168838
IDE insulin-degrading enzyme -0.0168778
KSR1 kinase suppressor of ras 1 -0.0168556
TRIP4 thyroid hormone receptor interactor 4 -0.0168244
ZBTB35 zinc finger and BTB domain containing 35 -0.0167966
ESYT2 extended synaptotagmin-like protein 2 -0.0167793
RTF2 replication termination factor 2 -0.0167594
RNPS1 RNA binding protein S1, serine-rich domain -0.0167346
UBN2 ubinuclein 2 -0.0167083
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0166956
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0166704
ITSN1 intersectin 1 (SH3 domain protein) -0.0166593
BCLAF3 BCLAF1 and THRAP3 family member 3 -0.0166387
ACOT9 acyl-CoA thioesterase 9 -0.0165894
DCDC1 doublecortin domain containing 1 -0.016576
UNK unkempt family zinc finger -0.0165741
TRIM9 tripartite motif containing 9 -0.0165546
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0165161
LARS2 leucyl-tRNA synthetase 2, mitochondrial -0.0165052
PON2 paraoxonase 2 -0.0165046
MRTFA myocardin related transcription factor A -0.0164601
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0164297
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0164095
CNPY2 canopy FGF signaling regulator 2 -0.0164087
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.016393
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0163781
TBC1D32 TBC1 domain family, member 32 -0.0163556
AZIN1 antizyme inhibitor 1 -0.0163139
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -0.0163025
ANXA7 annexin A7 -0.0162989
CRLF3 cytokine receptor-like factor 3 -0.0162982
KIF3B kinesin family member 3B -0.0162481
CARNMT1 carnosine N-methyltransferase 1 -0.0161881
FSTL4 follistatin-like 4 -0.0161712
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.0161257
NLN neurolysin (metallopeptidase M3 family) -0.0161253
MYADM myeloid-associated differentiation marker -0.016075
LTBP1 latent transforming growth factor beta binding protein 1 -0.0160444
NRP1 neuropilin 1 -0.0159948
STK39 serine threonine kinase 39 -0.0159932
PSPH phosphoserine phosphatase -0.0159856
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0159609
XXYLT1 xyloside xylosyltransferase 1 -0.0159209
FNBP1 formin binding protein 1 -0.0159076
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.015895
MAPK6 mitogen-activated protein kinase 6 -0.0158913
GCC2 GRIP and coiled-coil domain containing 2 -0.0158877
SEC24B SEC24 family member B -0.0158683
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0158659
SREBF2 sterol regulatory element binding transcription factor 2 -0.0158572
HGD homogentisate 1,2-dioxygenase -0.0157999
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.015798
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0157584
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.0157452
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.015705
UBAP2 ubiquitin associated protein 2 -0.0156619
TMEM156 transmembrane protein 156 -0.0156435
DDB2 damage-specific DNA binding protein 2, 48kDa -0.0156305
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0156257
GPR39 G protein-coupled receptor 39 -0.0156131
RPL11 ribosomal protein L11 -0.0155661
ELOF1 elongation factor 1 homolog (S. cerevisiae) -0.0155627
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0155568
LRP6 low density lipoprotein receptor-related protein 6 -0.0155487
TRAPPC9 trafficking protein particle complex 9 -0.0155471
PLCH1 phospholipase C, eta 1 -0.0155208
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.0155119
CLASRP CLK4-associating serine/arginine rich protein -0.0154905
RORA RAR-related orphan receptor A -0.0154835
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0154636
DPP8 dipeptidyl-peptidase 8 -0.0154632
CREBBP CREB binding protein -0.0154375
SRRM1 serine/arginine repetitive matrix 1 -0.0153913
ELL2 elongation factor, RNA polymerase II, 2 -0.0153769
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.015363
AREG amphiregulin -0.0153405
N4BP2L2 NEDD4 binding protein 2-like 2 -0.01533
PHGDH phosphoglycerate dehydrogenase -0.0153196
CUL4A cullin 4A -0.0152807
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0152784
CREM cAMP responsive element modulator -0.0152566
ADD3 adducin 3 (gamma) -0.0152559
ANKMY2 ankyrin repeat and MYND domain containing 2 -0.0152119
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -0.0152042
CLIP2 CAP-GLY domain containing linker protein 2 -0.0151892
NUP43 nucleoporin 43kDa -0.0151846
NCOA2 nuclear receptor coactivator 2 -0.0151833
ADGRV1 adhesion G protein-coupled receptor V1 -0.0151782
YEATS2 YEATS domain containing 2 -0.0151763
UBXN2A UBX domain protein 2A -0.0151657
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0151535
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0151335
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0151305
MFF mitochondrial fission factor -0.0151256
TOB1 transducer of ERBB2, 1 -0.0151034
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0150925
MYO10 myosin X -0.0150853
UBN1 ubinuclein 1 -0.015041
NCKAP1 NCK-associated protein 1 -0.0150312
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -0.0150145
VGLL4 vestigial-like family member 4 -0.0149928
LRMDA leucine rich melanocyte differentiation associated -0.0149635
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.0149574
RBMX RNA binding motif protein, X-linked -0.0149515
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -0.0149133
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0148713
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0148602
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0148177
ATAD2B ATPase family, AAA domain containing 2B -0.0148069
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.0147979
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0147821
COPB1 coatomer protein complex, subunit beta 1 -0.0147665
LARP4B La ribonucleoprotein domain family, member 4B -0.0147387
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -0.0146824
TOP1 topoisomerase (DNA) I -0.0146813
ATM ATM serine/threonine kinase -0.0146424
FAM149B1 family with sequence similarity 149, member B1 -0.0146273
RAP1B RAP1B, member of RAS oncogene family -0.0146138
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0145856
THSD4 thrombospondin, type I, domain containing 4 -0.0145791
STK32B serine/threonine kinase 32B -0.0145722
XPO6 exportin 6 -0.014563
LMTK2 lemur tyrosine kinase 2 -0.0145032
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0144984
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0144974
TMEM127 transmembrane protein 127 -0.014493
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.014487
FKTN fukutin -0.0144791
FKBP5 FK506 binding protein 5 -0.0144725
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0144639
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.0144465
KIF4A kinesin family member 4A -0.0144187
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -0.0144123
DGCR2 DiGeorge syndrome critical region gene 2 -0.0144069
ZNF518A zinc finger protein 518A -0.0144038
ARHGAP11B Rho GTPase activating protein 11B -0.0143776
ATXN2 ataxin 2 -0.0143676
USP32 ubiquitin specific peptidase 32 -0.0143615
RABL6 RAB, member RAS oncogene family-like 6 -0.014335
TEX10 testis expressed 10 -0.0143329
SYNRG synergin, gamma -0.0143214
CEP95 centrosomal protein 95kDa -0.0142724
WAC WW domain containing adaptor with coiled-coil -0.0142692
GLS2 glutaminase 2 (liver, mitochondrial) -0.0142057
EZR ezrin -0.0141918
SCFD1 sec1 family domain containing 1 -0.0141883
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.0141608
PLA2R1 phospholipase A2 receptor 1, 180kDa -0.0141585
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -0.0141438
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a -0.0141084
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.014087
DOCK10 dedicator of cytokinesis 10 -0.0140342
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.014019
PPARG peroxisome proliferator-activated receptor gamma -0.0140146
TMEM245 transmembrane protein 245 -0.0139926
SEPTIN11 septin 11 -0.0139848
RRM1 ribonucleotide reductase M1 -0.0139493