A549_Valproic acid sodium salt_1µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 1µM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_Valproic acid sodium salt_1µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
PDE4D phosphodiesterase 4D, cAMP-specific 0.201057
KRT18 keratin 18, type I 0.124966
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0996777
ACTN4 actinin, alpha 4 0.0885691
RAB10 RAB10, member RAS oncogene family 0.083642
RAD51B RAD51 paralog B 0.0756244
S100A6 S100 calcium binding protein A6 0.0630363
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0603389
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0602663
ANXA1 annexin A1 0.059473
KRT8 keratin 8, type II 0.0590253
PKM pyruvate kinase, muscle 0.057619
PDE4B phosphodiesterase 4B, cAMP-specific 0.0568665
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0512042
ARHGAP11B Rho GTPase activating protein 11B 0.0501148
GLIS3 GLIS family zinc finger 3 0.0494347
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0491543
S100A10 S100 calcium binding protein A10 0.0474786
MYO10 myosin X 0.0469139
RFX7 regulatory factor X, 7 0.0460613
KRT81 keratin 81, type II 0.0452202
NCOA3 nuclear receptor coactivator 3 0.0451411
CD44 CD44 molecule (Indian blood group) 0.0441218
ZBTB20 zinc finger and BTB domain containing 20 0.0438581
PARD3 par-3 family cell polarity regulator 0.0421711
NFIA nuclear factor I/A 0.0419699
ARHGAP18 Rho GTPase activating protein 18 0.0414141
CENPP centromere protein P 0.0410478
NRCAM neuronal cell adhesion molecule 0.0395803
GPC6 glypican 6 0.0387606
BMAL2 basic helix-loop-helix ARNT like 2 0.0386069
MGST1 microsomal glutathione S-transferase 1 0.0383826
ZNF367 zinc finger protein 367 0.0380284
ZNF609 zinc finger protein 609 0.0376653
TCF12 transcription factor 12 0.0376078
BCL2L1 BCL2-like 1 0.0368587
CERS6 ceramide synthase 6 0.0364045
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0351111
RBM47 RNA binding motif protein 47 0.034393
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0343772
LIMS1 LIM and senescent cell antigen-like domains 1 0.0339034
MYO9B myosin IXB 0.0336848
UGDH UDP-glucose 6-dehydrogenase 0.0334529
MED13L mediator complex subunit 13-like 0.0333461
EREG epiregulin 0.0328908
CCDC14 coiled-coil domain containing 14 0.0322926
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.0321993
FBXW11 F-box and WD repeat domain containing 11 0.0317387
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0316817
AK1 adenylate kinase 1 0.031555
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0314866
CLASP2 cytoplasmic linker associated protein 2 0.0313495
NAMPT nicotinamide phosphoribosyltransferase 0.0309724
PDE7B phosphodiesterase 7B 0.0309336
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0306737
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0306402
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0301476
TBC1D5 TBC1 domain family, member 5 0.0300452
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 0.0300295
SRPK1 SRSF protein kinase 1 0.0293566
TOP6BL TOP6B like initiator of meiotic double strand breaks 0.0290785
ASPH aspartate beta-hydroxylase 0.028975
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0288958
CCND3 cyclin D3 0.0288716
CNTLN centlein, centrosomal protein 0.0287733
ANXA2 annexin A2 0.0286775
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.0286173
TTLL10 tubulin tyrosine ligase-like family member 10 0.0284819
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.0284207
FAM120A family with sequence similarity 120A 0.0284098
NRIP1 nuclear receptor interacting protein 1 0.0284019
WASHC4 WASH complex subunit 4 0.0283256
SLIT3 slit homolog 3 (Drosophila) 0.028167
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0280923
GCLC glutamate-cysteine ligase, catalytic subunit 0.0280816
BLTP3B bridge-like lipid transfer protein family member 3B 0.0280409
TXNRD1 thioredoxin reductase 1 0.0279323
KIF21A kinesin family member 21A 0.0278975
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.027875
MAML3 mastermind-like 3 (Drosophila) 0.0278195
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0275895
DOCK10 dedicator of cytokinesis 10 0.0275675
AFG2A AFG2 AAA ATPase homolog A 0.0274796
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.0273171
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.0270535
SSH2 slingshot protein phosphatase 2 0.0269733
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0267319
TCF20 transcription factor 20 (AR1) 0.0266124
TRIM28 tripartite motif containing 28 0.0265935
MARCHF7 membrane associated ring-CH-type finger 7 0.0265613
ANKRD11 ankyrin repeat domain 11 0.0265377
BASP1 brain abundant, membrane attached signal protein 1 0.0264857
HEATR5B HEAT repeat containing 5B 0.0264637
RABL6 RAB, member RAS oncogene family-like 6 0.0264102
ZNHIT1 zinc finger, HIT-type containing 1 0.0263325
ATXN10 ataxin 10 0.0260227
KIF18B kinesin family member 18B 0.0256576
MPHOSPH9 M-phase phosphoprotein 9 0.0255402
FOXJ3 forkhead box J3 0.025306
CDC25C cell division cycle 25C 0.0252876
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.0251374
FAM13B family with sequence similarity 13, member B 0.0250233
GMPS guanine monphosphate synthase 0.0249884
ITCH itchy E3 ubiquitin protein ligase 0.0249464
SERBP1 SERPINE1 mRNA binding protein 1 0.0248405
IGF1R insulin-like growth factor 1 receptor 0.024768
SIK3 SIK family kinase 3 0.0246978
RAB6A RAB6A, member RAS oncogene family 0.0246834
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0246649
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0245744
ZFR zinc finger RNA binding protein 0.0243313
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0242946
TBC1D14 TBC1 domain family, member 14 0.0242769
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0241368
CMIP c-Maf inducing protein 0.0240348
FRK fyn-related Src family tyrosine kinase 0.0239831
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0238149
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.023797
ADGRA3 adhesion G protein-coupled receptor A3 0.0237955
ATAD2 ATPase family, AAA domain containing 2 0.0237063
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0236214
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.023503
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0234086
KDM2A lysine (K)-specific demethylase 2A 0.0232557
AZIN1 antizyme inhibitor 1 0.0231365
MORC4 MORC family CW-type zinc finger 4 0.0229715
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.0228983
TRAPPC9 trafficking protein particle complex 9 0.0228202
NSRP1 nuclear speckle splicing regulatory protein 1 0.0227309
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.0227011
PLCH1 phospholipase C, eta 1 0.0226859
PBX1 pre-B-cell leukemia homeobox 1 0.0226384
INVS inversin 0.0225841
WWOX WW domain containing oxidoreductase 0.0225834
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.0225066
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.022025
NONO non-POU domain containing, octamer-binding 0.0220226
LPP LIM domain containing preferred translocation partner in lipoma 0.0219809
RUSC2 RUN and SH3 domain containing 2 0.021967
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.0219395
FANCL Fanconi anemia, complementation group L 0.0219221
SSBP2 single-stranded DNA binding protein 2 0.0218445
DIAPH3 diaphanous-related formin 3 0.0218024
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0217816
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0217373
SKA2 spindle and kinetochore associated complex subunit 2 0.02166
LMNA lamin A/C 0.0216233
CCDC88A coiled-coil domain containing 88A 0.0216125
CENPI centromere protein I 0.0215833
AHCTF1 AT hook containing transcription factor 1 0.0215739
MCM8 minichromosome maintenance complex component 8 0.0215299
TK1 thymidine kinase 1, soluble 0.0215036
PCDH9 protocadherin 9 0.0214704
SEC11A SEC11 homolog A (S. cerevisiae) 0.0214678
PUM3 pumilio RNA binding family member 3 0.0214678
RNASE3 ribonuclease, RNase A family, 3 0.0214486
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0214296
TMED3 transmembrane emp24 protein transport domain containing 3 0.021424
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0213161
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0213075
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.021294
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.0212765
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.0212292
POGZ pogo transposable element with ZNF domain 0.0211473
ZBTB38 zinc finger and BTB domain containing 38 0.0211136
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0209805
EIF4A1 eukaryotic translation initiation factor 4A1 0.0209301
CST3 cystatin C 0.0208445
EBF1 early B-cell factor 1 0.0208282
POM121 POM121 transmembrane nucleoporin 0.0207084
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.020676
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0206155
BCAR3 breast cancer anti-estrogen resistance 3 0.0205327
KANK1 KN motif and ankyrin repeat domains 1 0.0204817
RBL1 retinoblastoma-like 1 0.0203633
HSPG2 heparan sulfate proteoglycan 2 0.0203499
ZMYND8 zinc finger, MYND-type containing 8 0.0203223
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.020164
RCOR1 REST corepressor 1 0.0201299
POFUT1 protein O-fucosyltransferase 1 0.0200767
H1-3 H1.3 linker histone, cluster member 0.0200457
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0200233
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.0199911
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0199825
PHF20L1 PHD finger protein 20-like 1 0.0199284
STIL SCL/TAL1 interrupting locus 0.0198877
WWTR1 WW domain containing transcription regulator 1 0.0198061
RNFT2 ring finger protein, transmembrane 2 0.0196648
GRK3 G protein-coupled receptor kinase 3 0.0196261
TRERF1 transcriptional regulating factor 1 0.0196198
CALR calreticulin 0.0196081
SETD2 SET domain containing 2 0.0195957
PRKCE protein kinase C, epsilon 0.0195844
WDR62 WD repeat domain 62 0.0194733
EIPR1 EARP complex and GARP complex interacting protein 1 0.0194102
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0193567
DCAF6 DDB1 and CUL4 associated factor 6 0.0193277
MAGT1 magnesium transporter 1 0.0192761
FANCI Fanconi anemia, complementation group I 0.0192532
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.0192362
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.019167
CUL3 cullin 3 0.0191432
PBRM1 polybromo 1 0.019131
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0191308
CDC42SE2 CDC42 small effector 2 0.0191289
PTPRA protein tyrosine phosphatase, receptor type, A 0.0190796
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0190737
BTBD9 BTB (POZ) domain containing 9 0.0190689
PACS1 phosphofurin acidic cluster sorting protein 1 0.0190658
AURKA aurora kinase A 0.0190132
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0189921
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0189469
SH3RF2 SH3 domain containing ring finger 2 0.0189425
IFFO2 intermediate filament family orphan 2 0.018913
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0188947
ERN1 endoplasmic reticulum to nucleus signaling 1 0.0188853
RSRC1 arginine/serine-rich coiled-coil 1 0.0187872
SARAF store-operated calcium entry-associated regulatory factor 0.0187265
NKTR natural killer cell triggering receptor 0.0186744
SNX24 sorting nexin 24 0.0186007
ACADVL acyl-CoA dehydrogenase, very long chain 0.0185218
NCOA2 nuclear receptor coactivator 2 0.0184695
ZMIZ1 zinc finger, MIZ-type containing 1 0.0184212
PDAP1 PDGFA associated protein 1 0.0183857
CAVIN1 caveolae associated protein 1 0.0183606
SCARB1 scavenger receptor class B, member 1 0.0182042
VCP valosin containing protein 0.0180425
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0180069
FNBP1L formin binding protein 1-like 0.0179981
EFNA5 ephrin-A5 0.0179937
SCFD2 sec1 family domain containing 2 0.017905
SBNO2 strawberry notch homolog 2 (Drosophila) 0.0178718
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.0178388
SLC45A4 solute carrier family 45, member 4 0.0178338
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.017825
ZZZ3 zinc finger, ZZ-type containing 3 0.0178043
CENPK centromere protein K 0.0177669
ABTB3 ankyrin repeat and BTB domain containing 3 0.0177632
CAPRIN1 cell cycle associated protein 1 0.0177415
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0177354
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0177298
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.0177167
FER fer (fps/fes related) tyrosine kinase 0.0176916
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.0176703
FAM219A family with sequence similarity 219, member A 0.0176584
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0176358
COL27A1 collagen, type XXVII, alpha 1 0.0175898
CACUL1 CDK2-associated, cullin domain 1 0.0175746
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.0174884
LDHA lactate dehydrogenase A 0.017472
DYNC2I2 dynein 2 intermediate chain 2 0.0174687
KIF3C kinesin family member 3C 0.017428
TMPRSS4 transmembrane protease, serine 4 0.0173834
SLC35F6 solute carrier family 35, member F6 0.0173272
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0173079
WDR70 WD repeat domain 70 0.0172986
TMEM209 transmembrane protein 209 0.01729
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0172488
TUBB tubulin, beta class I 0.0172245
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0172171
RTN3 reticulon 3 0.0171282
TNPO3 transportin 3 0.0171249
TMEM135 transmembrane protein 135 0.0171212
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.0169318
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0169068
OPN3 opsin 3 0.0168957
MASTL microtubule associated serine/threonine kinase-like 0.0168445
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.0168375
LIMCH1 LIM and calponin homology domains 1 0.016823
ABLIM1 actin binding LIM protein 1 0.0167995
CENPO centromere protein O 0.0167891
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0167873
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0167681
CUX1 cut-like homeobox 1 0.0167595
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0167314
TUBD1 tubulin, delta 1 0.016696
DEF8 differentially expressed in FDCP 8 homolog (mouse) 0.0166846
TTC23 tetratricopeptide repeat domain 23 0.0166646
PRKCI protein kinase C, iota 0.0166548
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.0165824
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.0164815
CELF1 CUGBP, Elav-like family member 1 0.0164649
MACROD1 MACRO domain containing 1 0.0163469
KIF18A kinesin family member 18A 0.0163065
LRRC23 leucine rich repeat containing 23 0.0163034
CDIN1 CDAN1 interacting nuclease 1 0.0162702
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.016263
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 0.0162623
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.01623
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.0162122
LIMD1 LIM domains containing 1 0.0161921
R3HDM2 R3H domain containing 2 0.0161499
MRPL24 mitochondrial ribosomal protein L24 0.016147
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 0.0161367
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.0161154
COPS3 COP9 signalosome subunit 3 0.0160903
NRF1 nuclear respiratory factor 1 0.0160324
BTBD1 BTB (POZ) domain containing 1 0.0160234
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0160116
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.0159846
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.0159827
SHKBP1 SH3KBP1 binding protein 1 0.0159546
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0159538
CENPU centromere protein U 0.0159314
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.0159211
ATG7 autophagy related 7 0.01588
MYO1B myosin IB 0.015821
CPAP centrosome assembly and centriole elongation protein 0.0158189
HPS5 Hermansky-Pudlak syndrome 5 0.0158135
TTC17 tetratricopeptide repeat domain 17 0.0157863
HCFC1 host cell factor C1 0.0157379
MMS22L MMS22-like, DNA repair protein 0.0156726
COX5A cytochrome c oxidase subunit Va 0.0156716
ARB2A ARB2 cotranscriptional regulator A 0.015658
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.0156495
XPC xeroderma pigmentosum, complementation group C 0.015631
LAMA5 laminin, alpha 5 0.0156035
MNX1 motor neuron and pancreas homeobox 1 0.0155591
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0155366
NSD3 nuclear receptor binding SET domain protein 3 0.0154671
ELP6 elongator acetyltransferase complex subunit 6 0.015461
MAST2 microtubule associated serine/threonine kinase 2 0.0154557
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0154237
ANAPC5 anaphase promoting complex subunit 5 0.0154162
CDK17 cyclin-dependent kinase 17 0.0154051
MALT1 MALT1 paracaspase 0.0153828
RPL35A ribosomal protein L35a 0.0153735
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.0153381
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 0.0152629
ICE1 interactor of little elongation complex ELL subunit 1 0.0152374
GON4L gon-4-like (C. elegans) 0.0152269
NCAPG non-SMC condensin I complex, subunit G 0.0152153
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0151875
SUGP2 SURP and G patch domain containing 2 0.0151471
RRBP1 ribosome binding protein 1 0.0151402
TLN2 talin 2 0.0151326
RAB2A RAB2A, member RAS oncogene family 0.0151316
NUAK2 NUAK family, SNF1-like kinase, 2 0.0151234
ANKRD13C ankyrin repeat domain 13C 0.0150751
CNOT1 CCR4-NOT transcription complex, subunit 1 0.01507
AIRIM AFG2 interacting ribosome maturation factor 0.0150667
TTC28 tetratricopeptide repeat domain 28 0.0150511
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 0.0150401
JAZF1 JAZF zinc finger 1 0.0149793
ZNF41 zinc finger protein 41 0.0149181
RRM1 ribonucleotide reductase M1 0.014876
PBK PDZ binding kinase 0.0148736
TBC1D4 TBC1 domain family, member 4 0.0148334
COMMD1 copper metabolism (Murr1) domain containing 1 0.0148325
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.0148181
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0148171
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0148068
MELK maternal embryonic leucine zipper kinase 0.0147726
HNF1A HNF1 homeobox A 0.0147647
SRPK2 SRSF protein kinase 2 0.0147519
TIMP1 TIMP metallopeptidase inhibitor 1 0.0147322
GMCL1 germ cell-less, spermatogenesis associated 1 0.014715
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 0.0146634
NSD2 nuclear receptor binding SET domain protein 2 0.0146512
EXO1 exonuclease 1 0.0146256
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.0146244
OXNAD1 oxidoreductase NAD-binding domain containing 1 0.0146214
MAP4 microtubule-associated protein 4 0.0145911
ATXN7 ataxin 7 0.0145749
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0145306
GPC1 glypican 1 0.0144995
MRPL20 mitochondrial ribosomal protein L20 0.0144712
BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 0.0144633
RSPO3 R-spondin 3 0.014416
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0144052
ZBED3 zinc finger, BED-type containing 3 0.0144044
EIF4A3 eukaryotic translation initiation factor 4A3 0.0143975
XRRA1 X-ray radiation resistance associated 1 0.0143711
LNPK lunapark, ER junction formation factor 0.0143581
HJURP Holliday junction recognition protein 0.0143513
USP22 ubiquitin specific peptidase 22 0.0143463
MGA MGA, MAX dimerization protein 0.0143286
SAMD4B sterile alpha motif domain containing 4B 0.014315
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.0143079
MRPS26 mitochondrial ribosomal protein S26 0.0142914
BMP6 bone morphogenetic protein 6 0.0142783
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.014274
INAVA innate immunity activator 0.014267
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.0142529
RBM39 RNA binding motif protein 39 0.0141394
NUP62 nucleoporin 62kDa 0.0141183
UFD1 ubiquitin recognition factor in ER associated degradation 1 0.0140427
PUM1 pumilio RNA-binding family member 1 0.0140296
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0140082
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.0139843
HSF1 heat shock transcription factor 1 0.0139567
ABI2 abl-interactor 2 0.0139299
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0139185
ZFAND3 zinc finger, AN1-type domain 3 0.0139142
FLYWCH1 FLYWCH-type zinc finger 1 0.0138968
PLPP1 phospholipid phosphatase 1 0.0138601
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 0.0138208
ERBIN erbb2 interacting protein 0.013792
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.0137812
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 0.0137787
ACTN1 actinin, alpha 1 0.0137737
LMNB1 lamin B1 0.01377
SREBF2 sterol regulatory element binding transcription factor 2 0.0137495
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.0137488
TPCN1 two pore segment channel 1 0.0137476
LARP1 La ribonucleoprotein domain family, member 1 0.0137457
CC2D1A coiled-coil and C2 domain containing 1A 0.0137365
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0137296
NLRP2 NLR family, pyrin domain containing 2 0.0136635
DHCR7 7-dehydrocholesterol reductase 0.0136457
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0136361
KRI1 KRI1 homolog (S. cerevisiae) 0.0136218
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0136186
TRAF3 TNF receptor-associated factor 3 0.0136079
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 0.0136057
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.0135705
RTN4 reticulon 4 0.0135673
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 0.0135641
TASP1 taspase, threonine aspartase, 1 0.0135444
ARL2 ADP-ribosylation factor-like 2 0.0135164
ITPK1 inositol-tetrakisphosphate 1-kinase 0.0134813
USP20 ubiquitin specific peptidase 20 0.0134761
HHIPL2 HHIP-like 2 0.0134376
UBTF upstream binding transcription factor, RNA polymerase I 0.0134143
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.0134127
RPL10A ribosomal protein L10a 0.0134115
TRAPPC1 trafficking protein particle complex 1 0.0133976
TGFBI transforming growth factor, beta-induced, 68kDa 0.0133721
TM7SF3 transmembrane 7 superfamily member 3 0.0133682
CDCA7L cell division cycle associated 7-like 0.0133673
ATAD2B ATPase family, AAA domain containing 2B 0.0133667
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.0133543
NALF1 NALCN channel auxiliary factor 1 0.0133503
PCSK5 proprotein convertase subtilisin/kexin type 5 0.0133383
MFSD11 major facilitator superfamily domain containing 11 0.0133029
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.013288
COL4A5 collagen, type IV, alpha 5 0.0132721
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0132658
GAN gigaxonin 0.0132637
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0132598
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.0132353
MPG N-methylpurine-DNA glycosylase 0.0132059
EIF3H eukaryotic translation initiation factor 3, subunit H 0.013188
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0131795
KIF20B kinesin family member 20B 0.0131669
BRCA1 breast cancer 1, early onset 0.0131666
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 0.0131593
ACSL4 acyl-CoA synthetase long-chain family member 4 0.0131263
HEATR1 HEAT repeat containing 1 0.013124
FAM13A family with sequence similarity 13, member A 0.0131083
ARID1A AT rich interactive domain 1A (SWI-like) 0.0130962
DCP2 decapping mRNA 2 0.0130908
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0130413
STMN1 stathmin 1 0.0130223
OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 0.0129916
SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B 0.0129878
ASTN2 astrotactin 2 0.0129679
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.0129517
ACTG1 actin gamma 1 0.0129317
ANAPC10 anaphase promoting complex subunit 10 0.0129314
PEAK1 pseudopodium-enriched atypical kinase 1 0.0129279
ZNRF3 zinc and ring finger 3 0.0129016
TSC2 tuberous sclerosis 2 0.0128905
NCBP3 nuclear cap binding subunit 3 0.012874
TPR translocated promoter region, nuclear basket protein 0.0128715
PEX26 peroxisomal biogenesis factor 26 0.0128598
NOP14 NOP14 nucleolar protein 0.0128444
SCAI suppressor of cancer cell invasion 0.0128386
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.0128219
CNKSR3 CNKSR family member 3 0.0127952
SMG5 SMG5 nonsense mediated mRNA decay factor 0.0127882
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0127721
ZFX zinc finger protein, X-linked 0.0127338
SYTL4 synaptotagmin-like 4 0.0127283
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0127204
MTMR4 myotubularin related protein 4 0.0127097
BMERB1 bMERB domain containing 1 0.012709
DHCR24 24-dehydrocholesterol reductase 0.0127059
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0127003
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.0126991
CEP295 centrosomal protein 295kDa 0.0126856
TGOLN2 trans-golgi network protein 2 0.0126681
ZMYM1 zinc finger, MYM-type 1 0.0126555
SON SON DNA binding protein 0.0125918
ZFAND5 zinc finger, AN1-type domain 5 0.0125781
SQLE squalene epoxidase 0.0125699
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.0125571
RAD18 RAD18 E3 ubiquitin protein ligase 0.0125571
NOM1 nucleolar protein with MIF4G domain 1 0.0125568
RAI14 retinoic acid induced 14 0.012518
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.0125089
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.0125058
TMEM245 transmembrane protein 245 0.0125023
GEN1 GEN1 Holliday junction 5' flap endonuclease 0.0125018
MCM6 minichromosome maintenance complex component 6 0.0125009
KIF14 kinesin family member 14 0.0124997
RPS14 ribosomal protein S14 0.0124819
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 0.0124751
CTIF CBP80/20-dependent translation initiation factor 0.0124448
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.012396

decreased expression

Symbol Name Standardized Value
CA12 carbonic anhydrase XII -0.158577
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.122671
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.109874
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0880001
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0860783
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0842119
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0824253
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0712318
CLU clusterin -0.0683137
BIRC6 baculoviral IAP repeat containing 6 -0.0666284
KYNU kynureninase -0.0634703
AKR1C2 aldo-keto reductase family 1, member C2 -0.0588924
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0562501
NRG1 neuregulin 1 -0.0557556
EML4 echinoderm microtubule associated protein like 4 -0.0553478
CP ceruloplasmin (ferroxidase) -0.0545282
MTUS1 microtubule associated tumor suppressor 1 -0.0541981
CNTN1 contactin 1 -0.0539894
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0530118
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0502376
CNTNAP3B contactin associated protein-like 3B -0.0486884
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0482887
RPL13A ribosomal protein L13a -0.0479874
RPS16 ribosomal protein S16 -0.0478509
CLIP1 CAP-GLY domain containing linker protein 1 -0.0469604
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0469188
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0464211
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0463441
IGFBP4 insulin-like growth factor binding protein 4 -0.0463128
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0453196
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0451223
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0450592
GRAMD1A GRAM domain containing 1A -0.0445915
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0438379
DENND4A DENN/MADD domain containing 4A -0.043535
TNRC18 trinucleotide repeat containing 18 -0.0430685
ARHGAP5 Rho GTPase activating protein 5 -0.0426032
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0424993
RPS3 ribosomal protein S3 -0.0424224
FOXP1 forkhead box P1 -0.0424159
MCU mitochondrial calcium uniporter -0.0421208
SPAG9 sperm associated antigen 9 -0.0420142
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0413546
AGR2 anterior gradient 2 -0.0413414
RPS11 ribosomal protein S11 -0.0412913
PDS5A PDS5 cohesin associated factor A -0.0412553
EHBP1 EH domain binding protein 1 -0.0410376
SFTPA2 surfactant protein A2 -0.0395365
NCOR1 nuclear receptor corepressor 1 -0.0393687
RAB1A RAB1A, member RAS oncogene family -0.0388824
PHGDH phosphoglycerate dehydrogenase -0.0388763
PM20D1 peptidase M20 domain containing 1 -0.0384352
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0382984
GLG1 golgi glycoprotein 1 -0.0379458
S100A4 S100 calcium binding protein A4 -0.0376513
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0371
FN1 fibronectin 1 -0.0370298
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0368438
BMPR1B bone morphogenetic protein receptor, type IB -0.0366339
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0366025
DOCK5 dedicator of cytokinesis 5 -0.0364899
SVIL supervillin -0.0364272
AKAP13 A kinase (PRKA) anchor protein 13 -0.0362738
RPLP1 ribosomal protein, large, P1 -0.0361859
CFH complement factor H -0.0359208
SETD5 SET domain containing 5 -0.0358249
GRAMD1B GRAM domain containing 1B -0.0357754
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0357507
NCOR2 nuclear receptor corepressor 2 -0.0356425
LRP10 low density lipoprotein receptor-related protein 10 -0.0355516
CANX calnexin -0.0353206
MAP1B microtubule-associated protein 1B -0.0342388
DNAAF9 dynein axonemal assembly factor 9 -0.0341558
TAOK1 TAO kinase 1 -0.0340114
MLPH melanophilin -0.0333304
JUP junction plakoglobin -0.0332864
KMT5B lysine methyltransferase 5B -0.0332421
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0329188
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0329149
ARHGAP26 Rho GTPase activating protein 26 -0.0328899
PRPF8 pre-mRNA processing factor 8 -0.03287
LRMDA leucine rich melanocyte differentiation associated -0.0325718
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0324689
SERINC5 serine incorporator 5 -0.0324154
BCAS3 breast carcinoma amplified sequence 3 -0.0323575
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0323315
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0322325
FTL ferritin, light polypeptide -0.0319926
FMNL2 formin-like 2 -0.0315307
LDLR low density lipoprotein receptor -0.0313955
RPS19 ribosomal protein S19 -0.0310455
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.0309892
ACYP2 acylphosphatase 2, muscle type -0.0308782
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0306644
ARHGAP12 Rho GTPase activating protein 12 -0.0306579
VDAC2 voltage-dependent anion channel 2 -0.0305667
KTN1 kinectin 1 (kinesin receptor) -0.0305315
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0304757
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0303404
ATXN3 ataxin 3 -0.030236
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0302145
FTH1 ferritin, heavy polypeptide 1 -0.0301142
P4HB prolyl 4-hydroxylase, beta polypeptide -0.029979
FCGBP Fc fragment of IgG binding protein -0.0299395
ATM ATM serine/threonine kinase -0.0298622
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 -0.0297436
CDR2 cerebellar degeneration-related protein 2, 62kDa -0.0294511
KRT7 keratin 7, type II -0.0294115
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0293583
RPL19 ribosomal protein L19 -0.029297
RPS21 ribosomal protein S21 -0.0291827
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0288267
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.0288217
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0286669
FNDC3A fibronectin type III domain containing 3A -0.0286135
RIN2 Ras and Rab interactor 2 -0.0285538
CAMKMT calmodulin-lysine N-methyltransferase -0.0285376
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0284716
SPATS2 spermatogenesis associated, serine-rich 2 -0.0283189
PATJ PATJ crumbs cell polarity complex component -0.0280865
RPL8 ribosomal protein L8 -0.028035
NCEH1 neutral cholesterol ester hydrolase 1 -0.0278618
MICU1 mitochondrial calcium uptake 1 -0.0278603
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0278268
FILIP1 filamin A interacting protein 1 -0.0278055
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.027798
TRIO trio Rho guanine nucleotide exchange factor -0.0277635
SH3D19 SH3 domain containing 19 -0.0277511
TMCC1 transmembrane and coiled-coil domain family 1 -0.0275727
TKT transketolase -0.0272761
STX8 syntaxin 8 -0.0271501
CEP128 centrosomal protein 128kDa -0.0269412
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.0269191
AKAP9 A kinase (PRKA) anchor protein 9 -0.0268463
PDLIM5 PDZ and LIM domain 5 -0.02681
PCM1 pericentriolar material 1 -0.0265565
TPI1 triosephosphate isomerase 1 -0.0264712
GPX2 glutathione peroxidase 2 -0.0263534
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.0263026
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0262453
TM4SF1 transmembrane 4 L six family member 1 -0.0262178
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.026174
ARMH3 armadillo like helical domain containing 3 -0.0260777
SLC38A1 solute carrier family 38, member 1 -0.026041
ZNF638 zinc finger protein 638 -0.0259389
SCAF11 SR-related CTD-associated factor 11 -0.0259252
CD151 CD151 molecule (Raph blood group) -0.025841
SHLD1 shieldin complex subunit 1 -0.0258401
RREB1 ras responsive element binding protein 1 -0.0258317
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0257659
PCNX2 pecanex 2 -0.0255609
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0253476
MGLL monoglyceride lipase -0.0253086
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0252424
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0252136
WDR59 WD repeat domain 59 -0.0251563
GOLGB1 golgin B1 -0.0250312
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.0248535
ACER3 alkaline ceramidase 3 -0.0248042
NBEA neurobeachin -0.024645
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.024603
COMMD10 COMM domain containing 10 -0.0245865
SMAD2 SMAD family member 2 -0.0245515
PDE8A phosphodiesterase 8A -0.0244699
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.0243722
UBAP2 ubiquitin associated protein 2 -0.024358
GOLGA4 golgin A4 -0.0243478
NEMF nuclear export mediator factor -0.024303
RAB5A RAB5A, member RAS oncogene family -0.0240113
PCYOX1 prenylcysteine oxidase 1 -0.023996
ELMO1 engulfment and cell motility 1 -0.0239382
PTGR1 prostaglandin reductase 1 -0.0239006
ZNF518A zinc finger protein 518A -0.0238906
AHNAK2 AHNAK nucleoprotein 2 -0.0238702
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0238201
NHSL1 NHS-like 1 -0.0236048
RBM6 RNA binding motif protein 6 -0.0235997
FAF1 Fas (TNFRSF6) associated factor 1 -0.0235565
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0235077
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0235057
TNRC6A trinucleotide repeat containing 6A -0.0235033
IRS2 insulin receptor substrate 2 -0.023426
NIPBL Nipped-B homolog (Drosophila) -0.0233294
TRA2A transformer 2 alpha homolog (Drosophila) -0.0232768
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0232692
PPP1R21 protein phosphatase 1, regulatory subunit 21 -0.0232645
PDIA4 protein disulfide isomerase family A, member 4 -0.0232607
KDM5B lysine (K)-specific demethylase 5B -0.0232585
SCN8A sodium channel, voltage gated, type VIII alpha subunit -0.0232168
TJP1 tight junction protein 1 -0.0232031
LARP4B La ribonucleoprotein domain family, member 4B -0.0231479
OGA O-GlcNAcase -0.0230552
FGB fibrinogen beta chain -0.0230121
BPTF bromodomain PHD finger transcription factor -0.0230114
KLHL5 kelch-like family member 5 -0.0229726
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0228904
TAPBP TAP binding protein (tapasin) -0.0228481
AKR1C1 aldo-keto reductase family 1, member C1 -0.0227911
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0227315
TTC7A tetratricopeptide repeat domain 7A -0.022696
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 -0.0226951
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0226797
SEC23A Sec23 homolog A (S. cerevisiae) -0.02267
RPL15 ribosomal protein L15 -0.0226463
IGFBP3 insulin-like growth factor binding protein 3 -0.0226373
NUCB1 nucleobindin 1 -0.0226263
MUSK muscle, skeletal, receptor tyrosine kinase -0.022623
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.0225215
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0224125
PCED1B PC-esterase domain containing 1B -0.0224038
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0222891
MPRIP myosin phosphatase Rho interacting protein -0.0222603
SLC38A2 solute carrier family 38, member 2 -0.0222297
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.0222171
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -0.022207
AKAP12 A kinase (PRKA) anchor protein 12 -0.0221663
MACROD2 MACRO domain containing 2 -0.0221503
CDK13 cyclin-dependent kinase 13 -0.0221483
ATOSA atos homolog A -0.0221321
SETBP1 SET binding protein 1 -0.0218663
TACC1 transforming, acidic coiled-coil containing protein 1 -0.0217606
PHF21A PHD finger protein 21A -0.0217063
CALD1 caldesmon 1 -0.0217046
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.0216215
REPS1 RALBP1 associated Eps domain containing 1 -0.0216207
GCC2 GRIP and coiled-coil domain containing 2 -0.021546
TMEM87A transmembrane protein 87A -0.0215313
TP63 tumor protein p63 -0.0214975
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0214959
LASP1 LIM and SH3 protein 1 -0.021492
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0214862
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0214367
ETNK1 ethanolamine kinase 1 -0.021324
PLD5 phospholipase D family, member 5 -0.021323
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 -0.0212773
PLS3 plastin 3 -0.0212664
GSPT1 G1 to S phase transition 1 -0.021165
AKR1C3 aldo-keto reductase family 1, member C3 -0.0211195
CYSTM1 cysteine-rich transmembrane module containing 1 -0.0211024
RFWD3 ring finger and WD repeat domain 3 -0.0209507
LHFPL2 lipoma HMGIC fusion partner-like 2 -0.0208475
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0207836
CLTC clathrin, heavy chain (Hc) -0.0207806
SEC31A SEC31 homolog A (S. cerevisiae) -0.0205895
SMAD5 SMAD family member 5 -0.020489
FLNA filamin A, alpha -0.0204809
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.0203515
ZSWIM7 zinc finger, SWIM-type containing 7 -0.0202467
RBBP8 retinoblastoma binding protein 8 -0.020212
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0201987
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -0.0201852
CAPNS1 calpain, small subunit 1 -0.0200517
C19ORF12 chromosome 19 open reading frame 12 -0.0200172
MTCL1 microtubule crosslinking factor 1 -0.0200113
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0200013
CORO2A coronin, actin binding protein, 2A -0.0199937
TMEM156 transmembrane protein 156 -0.0199589
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0199465
VEZT vezatin, adherens junctions transmembrane protein -0.0198042
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.019803
KDM5A lysine (K)-specific demethylase 5A -0.0197497
KIAA0319L KIAA0319-like -0.0197376
NEBL nebulette -0.0196172
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0195562
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0195341
ABR active BCR-related -0.0194625
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -0.0194492
ZNF652 zinc finger protein 652 -0.0194091
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0194064
DGKG diacylglycerol kinase, gamma 90kDa -0.0193734
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0193696
NTN4 netrin 4 -0.0193481
PPIA peptidylprolyl isomerase A (cyclophilin A) -0.0193333
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.019315
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 -0.0192889
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0191934
NAP1L1 nucleosome assembly protein 1-like 1 -0.0191839
HOMER2 homer scaffolding protein 2 -0.0191497
TUG1 taurine up-regulated 1 (non-protein coding) -0.019092
TET3 tet methylcytosine dioxygenase 3 -0.0190852
GRID1 glutamate receptor, ionotropic, delta 1 -0.0190632
XRN1 5'-3' exoribonuclease 1 -0.0190058
BRD4 bromodomain containing 4 -0.0189347
CPT1A carnitine palmitoyltransferase 1A (liver) -0.0189315
RAB11FIP3 RAB11 family interacting protein 3 (class II) -0.0188999
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -0.0188948
CSDE1 cold shock domain containing E1, RNA-binding -0.0188885
AHI1 Abelson helper integration site 1 -0.0188757
ZDHHC17 zinc finger, DHHC-type containing 17 -0.0188754
PECR peroxisomal trans-2-enoyl-CoA reductase -0.0188674
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.0188674
OSBPL10 oxysterol binding protein-like 10 -0.0188566
TMC5 transmembrane channel-like 5 -0.018841
DST dystonin -0.0188028
OPHN1 oligophrenin 1 -0.0188028
KIF13B kinesin family member 13B -0.0187874
PPARG peroxisome proliferator-activated receptor gamma -0.0187848
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -0.0187106
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0186026
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -0.0184717
SERGEF secretion regulating guanine nucleotide exchange factor -0.0184361
YBX3 Y box binding protein 3 -0.0184206
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.0184081
FAF2 Fas associated factor family member 2 -0.018408
SECISBP2L SECIS binding protein 2-like -0.0184033
RGS17 regulator of G-protein signaling 17 -0.0183497
ATP5MC2 ATP synthase membrane subunit c locus 2 -0.0183417
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0183361
STIM1 stromal interaction molecule 1 -0.0183344
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0183294
MSI2 musashi RNA-binding protein 2 -0.0183254
FGG fibrinogen gamma chain -0.0182843
ERMP1 endoplasmic reticulum metallopeptidase 1 -0.0182731
TMEM65 transmembrane protein 65 -0.018259
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0182518
KMT2E lysine (K)-specific methyltransferase 2E -0.0182516
MYO6 myosin VI -0.0182348
MACROH2A1 macroH2A.1 histone -0.0182043
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -0.0181774
MAP7 microtubule-associated protein 7 -0.0181336
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.0181243
R3HDM1 R3H domain containing 1 -0.0180503
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.0180115
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -0.0180001
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0179843
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0179648
PON2 paraoxonase 2 -0.0179558
WNT7B wingless-type MMTV integration site family, member 7B -0.0178836
PLAAT3 phospholipase A and acyltransferase 3 -0.0178501
UNK unkempt family zinc finger -0.0178212
UBE4A ubiquitination factor E4A -0.0177501
LRRK2 leucine-rich repeat kinase 2 -0.0177246
ZNF618 zinc finger protein 618 -0.0177189
SIN3A SIN3 transcription regulator family member A -0.0177132
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.017625
ECI1 enoyl-CoA delta isomerase 1 -0.0175909
MORF4L1 mortality factor 4 like 1 -0.0174912
LITAF lipopolysaccharide-induced TNF factor -0.0174874
PSEN1 presenilin 1 -0.0174675
NGLY1 N-glycanase 1 -0.0174614
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0174579
TGFB2 transforming growth factor, beta 2 -0.0174398
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.0174339
USP25 ubiquitin specific peptidase 25 -0.0174317
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0174108
APP amyloid beta (A4) precursor protein -0.017404
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -0.017374
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0173708
SIRT1 sirtuin 1 -0.0173346
TAOK3 TAO kinase 3 -0.017301
STRN3 striatin, calmodulin binding protein 3 -0.017121
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0171146
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0170974
PLD3 phospholipase D family, member 3 -0.017078
LAMP2 lysosomal-associated membrane protein 2 -0.0170734
VIM vimentin -0.0170717
SBF2 SET binding factor 2 -0.0170643
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0170058
MYRF myelin regulatory factor -0.0169792
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.0169651
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -0.0169509
SESTD1 SEC14 and spectrin domains 1 -0.0169384
SPRED1 sprouty-related, EVH1 domain containing 1 -0.0169355
AOPEP aminopeptidase O (putative) -0.0169128
CCNT1 cyclin T1 -0.0168966
PTPRM protein tyrosine phosphatase, receptor type, M -0.0168814
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -0.0168642
NUMA1 nuclear mitotic apparatus protein 1 -0.0168614
WDR44 WD repeat domain 44 -0.0168187
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0168054
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0167979
KDM4B lysine (K)-specific demethylase 4B -0.0167482
PTPRG protein tyrosine phosphatase, receptor type, G -0.0166977
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0166582
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -0.0166231
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0166203
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -0.0166134
HKDC1 hexokinase domain containing 1 -0.0166111
TMEM41B transmembrane protein 41B -0.016602
MRRF mitochondrial ribosome recycling factor -0.0165963
PIR pirin (iron-binding nuclear protein) -0.0165893
COG4 component of oligomeric golgi complex 4 -0.0165759
PLXNA2 plexin A2 -0.0165369
RBM33 RNA binding motif protein 33 -0.0165358
CEP350 centrosomal protein 350kDa -0.0165337
MTA3 metastasis associated 1 family, member 3 -0.0164712
AATF apoptosis antagonizing transcription factor -0.0164665
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0164566
FKBP1A FK506 binding protein 1A, 12kDa -0.0164284
FOXK2 forkhead box K2 -0.0164084
PDCD6IP programmed cell death 6 interacting protein -0.0164069
XBP1 X-box binding protein 1 -0.0163987
ITGA6 integrin, alpha 6 -0.0163902
ZMPSTE24 zinc metallopeptidase STE24 -0.0163822
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -0.0163774
JMJD1C jumonji domain containing 1C -0.0163585
QTMAN queuosine-tRNA mannosyltransferase -0.0163189
ALCAM activated leukocyte cell adhesion molecule -0.0163146
FGFR1 fibroblast growth factor receptor 1 -0.0162674
ADAM17 ADAM metallopeptidase domain 17 -0.0162258
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0162208
UBE2H ubiquitin-conjugating enzyme E2H -0.0161785
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.0161572
SNX9 sorting nexin 9 -0.0161375
ERH enhancer of rudimentary homolog (Drosophila) -0.0160902
ARMC9 armadillo repeat containing 9 -0.0160897
ASPHD1 aspartate beta-hydroxylase domain containing 1 -0.0160631
KIF3B kinesin family member 3B -0.0160616
RHOBTB3 Rho-related BTB domain containing 3 -0.0160557
SH3RF1 SH3 domain containing ring finger 1 -0.0160231
LIMA1 LIM domain and actin binding 1 -0.0160204
RNF213 ring finger protein 213 -0.0159758
RAP1B RAP1B, member of RAS oncogene family -0.0159129
FBXL2 F-box and leucine-rich repeat protein 2 -0.0159041
THRB thyroid hormone receptor, beta -0.0158989
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0158534
KIF13A kinesin family member 13A -0.0158496
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0158424
RIOK3 RIO kinase 3 -0.0158412
RPL23 ribosomal protein L23 -0.0158305
ACIN1 apoptotic chromatin condensation inducer 1 -0.0158231
RPS20 ribosomal protein S20 -0.0157285
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -0.0157153
PNISR PNN-interacting serine/arginine-rich protein -0.0157048
KIAA0232 KIAA0232 -0.0156634
PLCB4 phospholipase C, beta 4 -0.0156176
AUP1 ancient ubiquitous protein 1 -0.015605
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0155684
TM9SF3 transmembrane 9 superfamily member 3 -0.0155574
ENSA endosulfine alpha -0.0155166
TLK1 tousled-like kinase 1 -0.0155001
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0154774
TP53 tumor protein p53 -0.0154426
UEVLD UEV and lactate/malate dehyrogenase domains -0.0154402
DOCK9 dedicator of cytokinesis 9 -0.0154376
IRS1 insulin receptor substrate 1 -0.0154049
USP36 ubiquitin specific peptidase 36 -0.015398
RND1 Rho family GTPase 1 -0.0153772
KIFC3 kinesin family member C3 -0.0153335
RAB31 RAB31, member RAS oncogene family -0.015321
RUFY2 RUN and FYVE domain containing 2 -0.0152975
SERINC3 serine incorporator 3 -0.0152654
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0152425
PARM1 prostate androgen-regulated mucin-like protein 1 -0.0152357
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0152313
PARK7 parkinson protein 7 -0.015197
RPS29 ribosomal protein S29 -0.0151842
RPN2 ribophorin II -0.0151534
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -0.0151529
ZC3H3 zinc finger CCCH-type containing 3 -0.0151426
UBQLN1 ubiquilin 1 -0.01511
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0150662
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0150461
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -0.0150358
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0150319
SSR1 signal sequence receptor, alpha -0.0150233
BICRAL BICRA like chromatin remodeling complex associated protein -0.0149968
RABGAP1 RAB GTPase activating protein 1 -0.0149662
ANAPC11 anaphase promoting complex subunit 11 -0.0149418
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.0149405
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0149357
WDFY3 WD repeat and FYVE domain containing 3 -0.0149316
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -0.0149088
RNF103-CHMP3 RNF103-CHMP3 readthrough -0.014901
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0148713
ITSN1 intersectin 1 (SH3 domain protein) -0.0148526
KIF1C kinesin family member 1C -0.014832
GARNL3 GTPase activating Rap/RanGAP domain-like 3 -0.0148257
AKT2 v-akt murine thymoma viral oncogene homolog 2 -0.0147966
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -0.0147802
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0147748
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0147702
RPS6 ribosomal protein S6 -0.0147556
DSG2 desmoglein 2 -0.0147543
TBCD tubulin folding cofactor D -0.0147414
LDHB lactate dehydrogenase B -0.0147405
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0147294
EIF3K eukaryotic translation initiation factor 3, subunit K -0.0147222
SYT17 synaptotagmin XVII -0.0147165
ADNP activity-dependent neuroprotector homeobox -0.0147112
TPM4 tropomyosin 4 -0.0147094
NUCB2 nucleobindin 2 -0.0146881
STX5 syntaxin 5 -0.0146873
PTPRF protein tyrosine phosphatase, receptor type, F -0.0146698
FGD6 FYVE, RhoGEF and PH domain containing 6 -0.0146522
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0145913
SH3PXD2A SH3 and PX domains 2A -0.0145482
AMOTL1 angiomotin like 1 -0.0145153
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0145119
CAPN7 calpain 7 -0.0145079
FYCO1 FYVE and coiled-coil domain containing 1 -0.014495
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0144865
PGRMC2 progesterone receptor membrane component 2 -0.014475
IGSF11 immunoglobulin superfamily, member 11 -0.0144639
CDYL chromodomain protein, Y-like -0.0144546
USP54 ubiquitin specific peptidase 54 -0.0144133
CENPV centromere protein V -0.0143849
MYADM myeloid-associated differentiation marker -0.0143803
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0143521
ACBD3 acyl-CoA binding domain containing 3 -0.0143313