A549_Valproic acid sodium salt_10µM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 10µM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_Valproic acid sodium salt_10µM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT8 keratin 8, type II 0.109905
KRT18 keratin 18, type I 0.0950284
MAP7 microtubule-associated protein 7 0.0909473
CENPF centromere protein F, 350/400kDa 0.0847156
KRT81 keratin 81, type II 0.0785609
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0777536
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.075668
PTPRM protein tyrosine phosphatase, receptor type, M 0.0747351
NRCAM neuronal cell adhesion molecule 0.0738348
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0708534
SMYD3 SET and MYND domain containing 3 0.0686511
FLNB filamin B, beta 0.0583293
SPTBN1 spectrin, beta, non-erythrocytic 1 0.056685
ENO1 enolase 1, (alpha) 0.0558138
CAVIN1 caveolae associated protein 1 0.0527029
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0510642
GCLC glutamate-cysteine ligase, catalytic subunit 0.0496384
MTUS1 microtubule associated tumor suppressor 1 0.048845
UGDH UDP-glucose 6-dehydrogenase 0.0485169
BMAL2 basic helix-loop-helix ARNT like 2 0.0482202
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0470732
MTDH metadherin 0.046708
DOCK10 dedicator of cytokinesis 10 0.0454776
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0428779
GLIS3 GLIS family zinc finger 3 0.0428115
ACTN4 actinin, alpha 4 0.0424857
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0414171
LMNA lamin A/C 0.0410862
ASPH aspartate beta-hydroxylase 0.0404608
PDS5A PDS5 cohesin associated factor A 0.039199
FTL ferritin, light polypeptide 0.0389371
HIPK2 homeodomain interacting protein kinase 2 0.0388976
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.0388596
ANXA2 annexin A2 0.0384458
FLNA filamin A, alpha 0.0383972
PBX1 pre-B-cell leukemia homeobox 1 0.0376569
THADA thyroid adenoma associated 0.0365582
MYO1E myosin IE 0.0364487
CUEDC1 CUE domain containing 1 0.0358882
BRCA1 breast cancer 1, early onset 0.035663
SMC1A structural maintenance of chromosomes 1A 0.0354638
POLK polymerase (DNA directed) kappa 0.035303
ATAD2 ATPase family, AAA domain containing 2 0.0352762
NRF1 nuclear respiratory factor 1 0.0351753
ANXA1 annexin A1 0.0349173
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0347683
BRMS1L breast cancer metastasis-suppressor 1-like 0.0342098
PKP4 plakophilin 4 0.0340346
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0339571
MYOF myoferlin 0.0338502
KATNBL1 katanin p80 subunit B-like 1 0.0334286
CNTN1 contactin 1 0.0334
PCDHB16 protocadherin beta 16 0.0331359
CLTC clathrin, heavy chain (Hc) 0.0330942
MCU mitochondrial calcium uniporter 0.0330859
AKR1C3 aldo-keto reductase family 1, member C3 0.0329876
PARN poly(A)-specific ribonuclease 0.0329536
PDS5B PDS5 cohesin associated factor B 0.0327064
TOP1 topoisomerase (DNA) I 0.0326218
NEBL nebulette 0.0325533
PRICKLE2 prickle homolog 2 (Drosophila) 0.0325277
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.0324184
ZFHX3 zinc finger homeobox 3 0.0321718
CERT1 ceramide transporter 1 0.0320178
NSD2 nuclear receptor binding SET domain protein 2 0.031971
TMOD3 tropomodulin 3 (ubiquitous) 0.03189
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0317525
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0314077
ANKRD17 ankyrin repeat domain 17 0.0313744
BBX bobby sox homolog (Drosophila) 0.0312925
NUP107 nucleoporin 107kDa 0.0312596
MAP4 microtubule-associated protein 4 0.0312535
NRP1 neuropilin 1 0.0312418
BLM Bloom syndrome, RecQ helicase-like 0.0312294
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.0310993
PDE4B phosphodiesterase 4B, cAMP-specific 0.0310255
PRRC2B proline-rich coiled-coil 2B 0.0309931
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0308462
KPNB1 karyopherin (importin) beta 1 0.0308348
DNM2 dynamin 2 0.0308071
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0307591
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0306775
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0306516
TRIO trio Rho guanine nucleotide exchange factor 0.0306257
LRP5 low density lipoprotein receptor-related protein 5 0.0304731
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0301455
ARHGAP18 Rho GTPase activating protein 18 0.0300551
RPL28 ribosomal protein L28 0.0300288
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0299721
RNF115 ring finger protein 115 0.0299647
KCMF1 potassium channel modulatory factor 1 0.0296452
ACTG1 actin gamma 1 0.0294694
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.0293279
IQCB1 IQ motif containing B1 0.0292137
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0290717
PTPRA protein tyrosine phosphatase, receptor type, A 0.0289697
MSI2 musashi RNA-binding protein 2 0.0289481
ASXL2 additional sex combs like transcriptional regulator 2 0.0288706
SMC6 structural maintenance of chromosomes 6 0.0286033
CPLX2 complexin 2 0.0283044
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.0281128
NEMF nuclear export mediator factor 0.0280932
MYH9 myosin, heavy chain 9, non-muscle 0.0280891
PHGDH phosphoglycerate dehydrogenase 0.0280471
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 0.0279406
CPT1A carnitine palmitoyltransferase 1A (liver) 0.0279108
SLC35F3 solute carrier family 35, member F3 0.0278326
ZC3H3 zinc finger CCCH-type containing 3 0.0278217
PA2G4 proliferation-associated 2G4, 38kDa 0.0277822
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 0.0277602
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.027675
ADNP activity-dependent neuroprotector homeobox 0.0275334
GPC6 glypican 6 0.0275304
PDE10A phosphodiesterase 10A 0.0275139
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.027513
TAGLN2 transgelin 2 0.0274531
RNF216 ring finger protein 216 0.0274439
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0273456
CTBP2 C-terminal binding protein 2 0.0271845
ADAM10 ADAM metallopeptidase domain 10 0.027143
AAK1 AP2 associated kinase 1 0.0271162
IRF2BPL interferon regulatory factor 2 binding protein-like 0.027006
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0269275
SRPK2 SRSF protein kinase 2 0.026841
MED13L mediator complex subunit 13-like 0.0268395
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0267001
UIMC1 ubiquitin interaction motif containing 1 0.0266688
CD2AP CD2-associated protein 0.0266461
HELLS helicase, lymphoid-specific 0.0265598
AFG2A AFG2 AAA ATPase homolog A 0.0263983
NOL10 nucleolar protein 10 0.0263341
COL4A5 collagen, type IV, alpha 5 0.0263114
IPO7 importin 7 0.0262476
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0262004
PLCH1 phospholipase C, eta 1 0.0260601
SETX senataxin 0.026044
MACROH2A1 macroH2A.1 histone 0.0259781
KIF14 kinesin family member 14 0.0258791
HDAC2 histone deacetylase 2 0.0257984
NUP153 nucleoporin 153kDa 0.0257929
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0257312
STXBP4 syntaxin binding protein 4 0.0256125
MDN1 MDN1, midasin homolog (yeast) 0.0255058
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.0254516
NPAS2 neuronal PAS domain protein 2 0.0254121
AKAP13 A kinase (PRKA) anchor protein 13 0.0253842
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0253018
MPG N-methylpurine-DNA glycosylase 0.0252236
SNX27 sorting nexin family member 27 0.0250037
TASOR2 transcription activation suppressor family member 2 0.0249942
ACACA acetyl-CoA carboxylase alpha 0.0249383
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0249347
EXOC4 exocyst complex component 4 0.0248295
DIAPH3 diaphanous-related formin 3 0.024813
ATL2 atlastin GTPase 2 0.0247246
SMC4 structural maintenance of chromosomes 4 0.0246263
TPI1 triosephosphate isomerase 1 0.0244438
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0244082
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0243224
EPB41 erythrocyte membrane protein band 4.1 0.0243215
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0241871
MSRB3 methionine sulfoxide reductase B3 0.0241757
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.0241677
EIF5B eukaryotic translation initiation factor 5B 0.0240366
ACLY ATP citrate lyase 0.0239231
IRAK1 interleukin-1 receptor-associated kinase 1 0.0239225
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.0239081
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.0238514
PLEC plectin 0.0238093
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.0238067
PBX3 pre-B-cell leukemia homeobox 3 0.0237194
HJURP Holliday junction recognition protein 0.0237027
SCAI suppressor of cancer cell invasion 0.0235815
REPS1 RALBP1 associated Eps domain containing 1 0.0235526
QKI QKI, KH domain containing, RNA binding 0.02355
EIPR1 EARP complex and GARP complex interacting protein 1 0.0235112
AGO2 argonaute RISC catalytic component 2 0.0234847
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0234811
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0234394
RABGAP1L RAB GTPase activating protein 1-like 0.0234066
CAPN2 calpain 2, (m/II) large subunit 0.0233562
NRIP1 nuclear receptor interacting protein 1 0.0232103
TCERG1 transcription elongation regulator 1 0.0231566
CENPE centromere protein E, 312kDa 0.0231057
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0230648
KIF18B kinesin family member 18B 0.0230058
BMPR1A bone morphogenetic protein receptor, type IA 0.0229756
TIMELESS timeless circadian clock 0.0229715
MGST1 microsomal glutathione S-transferase 1 0.0228478
CDK6 cyclin-dependent kinase 6 0.0228221
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.0227992
GPC1 glypican 1 0.0227943
ARHGAP35 Rho GTPase activating protein 35 0.022714
TNRC6B trinucleotide repeat containing 6B 0.0226535
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.0226204
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.0225345
ZNF618 zinc finger protein 618 0.022527
ZMYND11 zinc finger, MYND-type containing 11 0.0224484
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0224466
ZNF644 zinc finger protein 644 0.0224127
STX8 syntaxin 8 0.0223909
SPC25 SPC25, NDC80 kinetochore complex component 0.0223812
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0222004
SH2D4A SH2 domain containing 4A 0.0221287
TBC1D4 TBC1 domain family, member 4 0.0220482
LIMS1 LIM and senescent cell antigen-like domains 1 0.0219454
PILRB paired immunoglobin-like type 2 receptor beta 0.0218919
ZNF281 zinc finger protein 281 0.0218576
SRBD1 S1 RNA binding domain 1 0.0218177
SENP1 SUMO1/sentrin specific peptidase 1 0.0217187
CEMIP cell migration inducing protein, hyaluronan binding 0.0214902
BPTF bromodomain PHD finger transcription factor 0.02146
NIPBL Nipped-B homolog (Drosophila) 0.0214516
CTTN cortactin 0.0213573
ZNF367 zinc finger protein 367 0.0213394
SPIDR scaffolding protein involved in DNA repair 0.021288
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0212716
SLC39A11 solute carrier family 39, member 11 0.021268
CENPP centromere protein P 0.0211891
EDN1 endothelin 1 0.0210524
DCAF1 DDB1 and CUL4 associated factor 1 0.0209932
PLCD3 phospholipase C, delta 3 0.0208519
ZZZ3 zinc finger, ZZ-type containing 3 0.0208503
RPL38 ribosomal protein L38 0.0208139
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.020807
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.0207725
NUMB numb homolog (Drosophila) 0.0207323
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0206183
PTBP2 polypyrimidine tract binding protein 2 0.0205927
SFXN5 sideroflexin 5 0.0204103
MUSK muscle, skeletal, receptor tyrosine kinase 0.020373
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.0203693
ECPAS Ecm29 proteasome adaptor and scaffold 0.0203597
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0202505
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.0202192
METTL16 methyltransferase like 16 0.0201719
RBMX RNA binding motif protein, X-linked 0.0200706
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 0.0200421
CEP128 centrosomal protein 128kDa 0.0200325
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0199982
PUM2 pumilio RNA-binding family member 2 0.0199883
MMS22L MMS22-like, DNA repair protein 0.0199588
DTD1 D-tyrosyl-tRNA deacylase 1 0.0199468
PARD3 par-3 family cell polarity regulator 0.0199451
RPH3AL rabphilin 3A-like (without C2 domains) 0.0199172
RAD51B RAD51 paralog B 0.0199094
LCLAT1 lysocardiolipin acyltransferase 1 0.0198362
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0197781
GPS1 G protein pathway suppressor 1 0.0197597
FOXO3 forkhead box O3 0.019748
MYO5A myosin VA (heavy chain 12, myoxin) 0.019688
PIR pirin (iron-binding nuclear protein) 0.0196775
ZGRF1 zinc finger, GRF-type containing 1 0.0196541
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.0196429
URGCP upregulator of cell proliferation 0.0196272
TMEM131 transmembrane protein 131 0.0196236
CLASRP CLK4-associating serine/arginine rich protein 0.0195893
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.0195152
ZCCHC7 zinc finger, CCHC domain containing 7 0.0194901
ATXN10 ataxin 10 0.0194718
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.019466
JADE1 jade family PHD finger 1 0.0194357
MARCHF7 membrane associated ring-CH-type finger 7 0.0193259
PON2 paraoxonase 2 0.0192827
MLEC malectin 0.0192727
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0192615
FTO fat mass and obesity associated 0.0192442
USP47 ubiquitin specific peptidase 47 0.019213
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0192053
SRSF10 serine/arginine-rich splicing factor 10 0.0191219
CASP8AP2 caspase 8 associated protein 2 0.01912
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.0190914
NSUN6 NOP2/Sun domain family, member 6 0.0190877
MGST3 microsomal glutathione S-transferase 3 0.0190734
NF1 neurofibromin 1 0.0190606
PSPC1 paraspeckle component 1 0.0190065
NCAPG non-SMC condensin I complex, subunit G 0.0190022
CHN1 chimerin 1 0.0189698
EPAS1 endothelial PAS domain protein 1 0.0189411
SMAD6 SMAD family member 6 0.0188667
SCLT1 sodium channel and clathrin linker 1 0.0188662
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.018787
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.0186473
ASTN2 astrotactin 2 0.0185955
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0184962
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.0184304
EML1 echinoderm microtubule associated protein like 1 0.0183955
NLK nemo-like kinase 0.0183555
SPATS2 spermatogenesis associated, serine-rich 2 0.0183457
FNBP4 formin binding protein 4 0.0183183
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0182906
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0182831
MTCL1 microtubule crosslinking factor 1 0.0182326
CLSTN1 calsyntenin 1 0.0181885
AKR1C2 aldo-keto reductase family 1, member C2 0.0181834
RHOBTB1 Rho-related BTB domain containing 1 0.0181569
FAM133B family with sequence similarity 133, member B 0.0181172
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0181091
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.018071
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0180621
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.0180461
SNX24 sorting nexin 24 0.0180345
TUBB4B tubulin, beta 4B class IVb 0.0180285
ELOF1 elongation factor 1 homolog (S. cerevisiae) 0.017989
PITRM1 pitrilysin metallopeptidase 1 0.0178821
ABLIM1 actin binding LIM protein 1 0.0178199
BICD2 bicaudal D homolog 2 (Drosophila) 0.0177865
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.017774
EIF4B eukaryotic translation initiation factor 4B 0.0177694
RNF121 ring finger protein 121 0.0177506
TSC2 tuberous sclerosis 2 0.0177455
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.0177434
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.0177187
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0177086
PGAP2 post-GPI attachment to proteins 2 0.0176939
TTC8 tetratricopeptide repeat domain 8 0.017651
CLASP2 cytoplasmic linker associated protein 2 0.0175947
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 0.0175537
SCAF11 SR-related CTD-associated factor 11 0.0175444
RRM1 ribonucleotide reductase M1 0.0175422
CNTLN centlein, centrosomal protein 0.0175235
TNRC6A trinucleotide repeat containing 6A 0.017491
NFIA nuclear factor I/A 0.0174845
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0174843
NCOR1 nuclear receptor corepressor 1 0.0174678
FUBP1 far upstream element (FUSE) binding protein 1 0.0174617
MYO10 myosin X 0.0174602
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.0174538
IPO9 importin 9 0.017449
SPOP speckle-type POZ protein 0.0174475
MTCH2 mitochondrial carrier 2 0.0174435
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.0174401
DCLK2 doublecortin-like kinase 2 0.0173498
VGLL4 vestigial-like family member 4 0.017347
ENAH enabled homolog (Drosophila) 0.0172711
PALB2 partner and localizer of BRCA2 0.0172488
CCDC142 coiled-coil domain containing 142 0.0172404
SIK3 SIK family kinase 3 0.017239
PDE4D phosphodiesterase 4D, cAMP-specific 0.0172358
UBL4A ubiquitin-like 4A 0.0172254
KIF4A kinesin family member 4A 0.0172123
UBE2N ubiquitin-conjugating enzyme E2N 0.0172047
FAR1 fatty acyl CoA reductase 1 0.0171714
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0171023
CMIP c-Maf inducing protein 0.0169249
EIF3B eukaryotic translation initiation factor 3, subunit B 0.0169101
WNK1 WNK lysine deficient protein kinase 1 0.0169073
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0168671
MYO19 myosin XIX 0.0168451
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.0168398
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0168251
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0168066
EIF4A3 eukaryotic translation initiation factor 4A3 0.0168008
PCNA proliferating cell nuclear antigen 0.0167926
NDRG3 NDRG family member 3 0.0166964
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.0166884
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.0166289
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 0.0166107
MCM6 minichromosome maintenance complex component 6 0.0166083
IQGAP1 IQ motif containing GTPase activating protein 1 0.0166049
SEPTIN10 septin 10 0.0165963
FAF1 Fas (TNFRSF6) associated factor 1 0.0165499
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0165177
CNOT10 CCR4-NOT transcription complex, subunit 10 0.0165105
MED24 mediator complex subunit 24 0.0165052
DDRGK1 DDRGK domain containing 1 0.0164877
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0164144
VRK2 vaccinia related kinase 2 0.0163797
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.0163605
NEO1 neogenin 1 0.0163557
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0162889
SEPTIN9 septin 9 0.0162631
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.0161803
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0161764
HROB homologous recombination factor with OB-fold 0.0161278
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.016104
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0160587
AKAP10 A kinase (PRKA) anchor protein 10 0.0160506
CERS6 ceramide synthase 6 0.0160452
KDM5A lysine (K)-specific demethylase 5A 0.016032
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0160017
AGTPBP1 ATP/GTP binding protein 1 0.0159962
SCFD2 sec1 family domain containing 2 0.0159799
SHTN1 shootin 1 0.0159484
DCTN1 dynactin 1 0.0159139
GPHN gephyrin 0.0158943
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0158413
RCC1 regulator of chromosome condensation 1 0.0158358
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0157981
KDM2A lysine (K)-specific demethylase 2A 0.0157794
EP300 E1A binding protein p300 0.0157685
WDR11 WD repeat domain 11 0.015737
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.0157188
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.0156837
ZNF75A zinc finger protein 75a 0.0156544
UNG uracil-DNA glycosylase 0.0156474
HOOK3 hook microtubule-tethering protein 3 0.0156352
ARB2A ARB2 cotranscriptional regulator A 0.0156145
PTCD3 pentatricopeptide repeat domain 3 0.0155852
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.01552
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 0.0155108
SRSF7 serine/arginine-rich splicing factor 7 0.0154889
ERBIN erbb2 interacting protein 0.0154842
NFIB nuclear factor I/B 0.0154715
CDKL5 cyclin-dependent kinase-like 5 0.015448
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.0154307
ATM ATM serine/threonine kinase 0.0154084
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 0.0154079
REEP3 receptor accessory protein 3 0.0154064
EIF6 eukaryotic translation initiation factor 6 0.0153781
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.0153738
PELI1 pellino E3 ubiquitin protein ligase 1 0.0153571
RHOC ras homolog family member C 0.0153357
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0153288
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0153087
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.0152977
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0152706
EGFR epidermal growth factor receptor 0.0152328
TUFM Tu translation elongation factor, mitochondrial 0.0152309
RBBP7 retinoblastoma binding protein 7 0.0152044
LIN9 lin-9 DREAM MuvB core complex component 0.015198
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.0151672
TNRC18 trinucleotide repeat containing 18 0.015143
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 0.0151426
TMEM135 transmembrane protein 135 0.0151266
CLINT1 clathrin interactor 1 0.0150993
RGS17 regulator of G-protein signaling 17 0.0150927
GANAB glucosidase, alpha; neutral AB 0.015064
LARP1 La ribonucleoprotein domain family, member 1 0.015057
BRCA2 breast cancer 2, early onset 0.0150465
RPN1 ribophorin I 0.0150115
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.015011
ATL3 atlastin GTPase 3 0.0149322
COL4A4 collagen, type IV, alpha 4 0.0149025
CTCF CCCTC-binding factor (zinc finger protein) 0.0149001
ZNF121 zinc finger protein 121 0.0148748
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.014874
MBNL1 muscleblind-like splicing regulator 1 0.0148238
OAZ1 ornithine decarboxylase antizyme 1 0.0148124
TFRC transferrin receptor 0.0148037
CREB1 cAMP responsive element binding protein 1 0.0147867
TBCD tubulin folding cofactor D 0.014783
TMEM41B transmembrane protein 41B 0.0147356
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 0.0147158
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 0.0146607
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 0.0146548
ARL2 ADP-ribosylation factor-like 2 0.0146497
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 0.014588
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.014576
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.0145585
MYO9A myosin IXA 0.0145444
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0145166
TMEM181 transmembrane protein 181 0.0145021
RAP1A RAP1A, member of RAS oncogene family 0.0144852
DIAPH1 diaphanous-related formin 1 0.0144813
CERK ceramide kinase 0.014477
ITPRID2 ITPR interacting domain containing 2 0.0144762
ZC3H13 zinc finger CCCH-type containing 13 0.0144676
LRP6 low density lipoprotein receptor-related protein 6 0.0144631
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.014463
COMMD4 COMM domain containing 4 0.0144602
BTN3A3 butyrophilin, subfamily 3, member A3 0.0144411
TULP3 tubby like protein 3 0.0144123
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0143938
SUMO2 small ubiquitin-like modifier 2 0.0143849
CENPK centromere protein K 0.0143826
SNX5 sorting nexin 5 0.0143793
ZC3H4 zinc finger CCCH-type containing 4 0.0143514
MED29 mediator complex subunit 29 0.0143248
SMAP1 small ArfGAP 1 0.0143159
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0143136
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.014308
FAM219A family with sequence similarity 219, member A 0.0143028
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0142748
TRERF1 transcriptional regulating factor 1 0.0142744
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.0142699
KDM5C lysine (K)-specific demethylase 5C 0.0142554
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0142541
JADE3 jade family PHD finger 3 0.0141993
RAP1GAP RAP1 GTPase activating protein 0.0141646
SH3RF2 SH3 domain containing ring finger 2 0.0141536
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.0141477
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.0141248
UHMK1 U2AF homology motif (UHM) kinase 1 0.0141018
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.0140984
RGS20 regulator of G-protein signaling 20 0.0140966
ARL4C ADP-ribosylation factor-like 4C 0.014089
TMPO thymopoietin 0.0140874
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.0140607
KIF23 kinesin family member 23 0.014058
FZD6 frizzled class receptor 6 0.014053
WWC1 WW and C2 domain containing 1 0.0140015
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0140006
EIF4E eukaryotic translation initiation factor 4E 0.013993
CCNL2 cyclin L2 0.0139891
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0139774
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0139551
GPATCH4 G patch domain containing 4 0.0139421
TXNRD1 thioredoxin reductase 1 0.0139322
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0139214

decreased expression

Symbol Name Standardized Value
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.128007
KYNU kynureninase -0.111651
FAM107B family with sequence similarity 107, member B -0.0975284
ZBTB20 zinc finger and BTB domain containing 20 -0.0928484
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0778103
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0686037
SQSTM1 sequestosome 1 -0.0657091
CA12 carbonic anhydrase XII -0.0650411
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0629762
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0567636
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0565452
RPS19 ribosomal protein S19 -0.0543698
FNDC3B fibronectin type III domain containing 3B -0.0538398
PRKCA protein kinase C, alpha -0.0536199
PRKCSH protein kinase C substrate 80K-H -0.0532962
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0532771
CST3 cystatin C -0.0532761
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0524304
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0524194
ARHGAP26 Rho GTPase activating protein 26 -0.0517745
BMPR1B bone morphogenetic protein receptor, type IB -0.050412
PTGR1 prostaglandin reductase 1 -0.0492
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0489563
THSD4 thrombospondin, type I, domain containing 4 -0.048295
CTSD cathepsin D -0.0476829
HIP1 huntingtin interacting protein 1 -0.0476023
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0475374
RASAL2 RAS protein activator like 2 -0.0461634
APP amyloid beta (A4) precursor protein -0.0455429
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0443183
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0439904
R3HDM2 R3H domain containing 2 -0.0439192
GPATCH8 G patch domain containing 8 -0.0438373
SBF2 SET binding factor 2 -0.043693
OPHN1 oligophrenin 1 -0.0434117
THRB thyroid hormone receptor, beta -0.0432185
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0430219
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.042732
RTN4 reticulon 4 -0.0424487
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0422618
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) -0.0420392
NRG1 neuregulin 1 -0.0417674
NCOA3 nuclear receptor coactivator 3 -0.0417461
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0416467
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0414928
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0413293
EFNA5 ephrin-A5 -0.0405966
LPP LIM domain containing preferred translocation partner in lipoma -0.0400798
BCL2L1 BCL2-like 1 -0.040041
FBXL20 F-box and leucine-rich repeat protein 20 -0.0399974
GPX2 glutathione peroxidase 2 -0.0399136
ATXN1 ataxin 1 -0.0398905
THSD7A thrombospondin, type I, domain containing 7A -0.0398507
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0397147
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0397047
CDK13 cyclin-dependent kinase 13 -0.0394898
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0394854
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0379989
BABAM2 BRISC and BRCA1 A complex member 2 -0.0376218
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0375533
ITSN2 intersectin 2 -0.0363243
TNS3 tensin 3 -0.036296
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0360907
TAOK3 TAO kinase 3 -0.0360553
SMAD2 SMAD family member 2 -0.0355162
MRPL13 mitochondrial ribosomal protein L13 -0.0355095
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0351448
AFF4 AF4/FMR2 family, member 4 -0.0348758
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.0348362
PATJ PATJ crumbs cell polarity complex component -0.0346453
CUX1 cut-like homeobox 1 -0.034364
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0343294
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0338989
ATXN3 ataxin 3 -0.033678
FHIT fragile histidine triad -0.0333799
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0333527
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0330274
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0326396
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0325974
CNTNAP3B contactin associated protein-like 3B -0.0323156
AGR2 anterior gradient 2 -0.0320441
AHI1 Abelson helper integration site 1 -0.0319751
MORF4L1 mortality factor 4 like 1 -0.0318883
FN1 fibronectin 1 -0.0317817
ANXA4 annexin A4 -0.031687
TMSB10 thymosin beta 10 -0.031508
MYADM myeloid-associated differentiation marker -0.0314789
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0314063
RPS3 ribosomal protein S3 -0.0312182
AKAP12 A kinase (PRKA) anchor protein 12 -0.0309931
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.0307662
FRMD3 FERM domain containing 3 -0.0306356
KAT6B K(lysine) acetyltransferase 6B -0.0305615
SPAG9 sperm associated antigen 9 -0.0305004
GMDS GDP-mannose 4,6-dehydratase -0.0304746
CLU clusterin -0.0303985
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.030156
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0299789
RIN2 Ras and Rab interactor 2 -0.0298245
EVA1C eva-1 homolog C (C. elegans) -0.0297794
RBM6 RNA binding motif protein 6 -0.0295733
BSG basigin (Ok blood group) -0.0294215
RAP1B RAP1B, member of RAS oncogene family -0.0292746
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0292455
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0291194
FOSL1 FOS-like antigen 1 -0.0289546
RNF145 ring finger protein 145 -0.0288682
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0288314
CNKSR3 CNKSR family member 3 -0.0286363
RACK1 receptor for activated C kinase 1 -0.0284235
GTF2IRD1 GTF2I repeat domain containing 1 -0.0283331
ZFAND6 zinc finger, AN1-type domain 6 -0.028304
CP ceruloplasmin (ferroxidase) -0.028279
PDE8A phosphodiesterase 8A -0.0280711
SPPL2A signal peptide peptidase like 2A -0.0278815
ANTXR1 anthrax toxin receptor 1 -0.0278589
RCOR1 REST corepressor 1 -0.0276925
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.0275952
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.027483
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0274164
AUTS2 autism susceptibility candidate 2 -0.0270989
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0270167
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0270058
SETD5 SET domain containing 5 -0.0269173
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0269021
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.026825
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0268106
CUL1 cullin 1 -0.026577
PDLIM5 PDZ and LIM domain 5 -0.026177
TLK2 tousled-like kinase 2 -0.0261385
SPPL3 signal peptide peptidase like 3 -0.026131
ZNF292 zinc finger protein 292 -0.0260641
PCED1B PC-esterase domain containing 1B -0.0259039
COBL cordon-bleu WH2 repeat protein -0.0258985
STK24 serine/threonine kinase 24 -0.0258547
LAMB1 laminin, beta 1 -0.0258015
PEAK1 pseudopodium-enriched atypical kinase 1 -0.02578
KRT7 keratin 7, type II -0.0257608
XRN2 5'-3' exoribonuclease 2 -0.0257274
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0256009
CALU calumenin -0.0255738
MYO1D myosin ID -0.0255673
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0255524
SHLD1 shieldin complex subunit 1 -0.0255425
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.0255022
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.025497
USP36 ubiquitin specific peptidase 36 -0.0254738
TBC1D5 TBC1 domain family, member 5 -0.0253327
ARL15 ADP-ribosylation factor-like 15 -0.0253108
STK39 serine threonine kinase 39 -0.0252757
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0248968
GFOD1 glucose-fructose oxidoreductase domain containing 1 -0.0247576
PRTG protogenin -0.0247564
CRTC3 CREB regulated transcription coactivator 3 -0.0247262
SSH2 slingshot protein phosphatase 2 -0.0247097
USP9X ubiquitin specific peptidase 9, X-linked -0.0246052
VSIG10 V-set and immunoglobulin domain containing 10 -0.0244456
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0244181
RPL30 ribosomal protein L30 -0.0241047
ITGB5 integrin, beta 5 -0.0240848
COP1 COP1 E3 ubiquitin ligase -0.0240291
SLC35F5 solute carrier family 35, member F5 -0.0237734
MAPK6 mitogen-activated protein kinase 6 -0.0237577
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0237032
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.023672
CLIP2 CAP-GLY domain containing linker protein 2 -0.0236066
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0235638
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.02349
FGA fibrinogen alpha chain -0.0234702
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0234477
CEMIP2 cell migration inducing hyaluronidase 2 -0.0234327
ZNF638 zinc finger protein 638 -0.0234257
SLTM SAFB-like, transcription modulator -0.0233925
RNF213 ring finger protein 213 -0.0233577
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.023332
ABR active BCR-related -0.0233301
JPT1 Jupiter microtubule associated homolog 1 -0.0232023
PTPRK protein tyrosine phosphatase, receptor type, K -0.0231389
ANKRD30A ankyrin repeat domain 30A -0.0230478
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.022987
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.0229869
TTC28 tetratricopeptide repeat domain 28 -0.0228627
MLPH melanophilin -0.0228617
TPM1 tropomyosin 1 (alpha) -0.0227887
CUL5 cullin 5 -0.0227839
WDFY3 WD repeat and FYVE domain containing 3 -0.0227519
FRY furry homolog (Drosophila) -0.0227279
RPS11 ribosomal protein S11 -0.0227148
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0225481
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0225446
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0225445
RB1CC1 RB1-inducible coiled-coil 1 -0.0225284
GRAMD1B GRAM domain containing 1B -0.0225235
NTN4 netrin 4 -0.0224747
SNX29 sorting nexin 29 -0.0224026
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0223259
BICD1 bicaudal D homolog 1 (Drosophila) -0.0222881
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0222214
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0222114
CD44 CD44 molecule (Indian blood group) -0.0221811
ARMH3 armadillo like helical domain containing 3 -0.0221772
APTX aprataxin -0.0220852
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0220747
TANK TRAF family member-associated NFKB activator -0.0220575
FOXK2 forkhead box K2 -0.0220518
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.0220239
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.0219717
AK3 adenylate kinase 3 -0.0219699
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0218804
TTC17 tetratricopeptide repeat domain 17 -0.0218702
JMJD1C jumonji domain containing 1C -0.0218421
TPT1 tumor protein, translationally-controlled 1 -0.0218294
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0217851
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -0.0217599
RPL18 ribosomal protein L18 -0.021758
GOLM1 golgi membrane protein 1 -0.0216777
PREPL prolyl endopeptidase-like -0.0216617
PUM1 pumilio RNA-binding family member 1 -0.0216548
PSEN1 presenilin 1 -0.021633
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.0216266
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.0216264
COG4 component of oligomeric golgi complex 4 -0.0216191
FGB fibrinogen beta chain -0.0215956
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0215909
FGFR1 fibroblast growth factor receptor 1 -0.0215516
RPS5 ribosomal protein S5 -0.0214662
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0214546
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0213314
PLPP1 phospholipid phosphatase 1 -0.0213183
RPS9 ribosomal protein S9 -0.0213011
FOXP1 forkhead box P1 -0.0212805
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0212683
TMEM156 transmembrane protein 156 -0.0212439
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.0212324
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0212014
LOC112694756 uncharaterized LOC112694756 -0.0211128
AATF apoptosis antagonizing transcription factor -0.0210696
DROSHA drosha, ribonuclease type III -0.0210547
PPA2 pyrophosphatase (inorganic) 2 -0.0210443
DOCK9 dedicator of cytokinesis 9 -0.0207273
DNMBP dynamin binding protein -0.0206391
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0206066
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0205938
CYRIB CYFIP related Rac1 interactor B -0.020587
PGK1 phosphoglycerate kinase 1 -0.0205657
ARSD arylsulfatase D -0.0205374
SEPTIN6 septin 6 -0.0205362
SPATA7 spermatogenesis associated 7 -0.0204986
USP8 ubiquitin specific peptidase 8 -0.0204899
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0204481
EXT1 exostosin glycosyltransferase 1 -0.0204132
METAP2 methionyl aminopeptidase 2 -0.02041
ZNF331 zinc finger protein 331 -0.0202364
RSF1 remodeling and spacing factor 1 -0.0202247
TRIM37 tripartite motif containing 37 -0.0201849
DAPK1 death-associated protein kinase 1 -0.0201718
CYSTM1 cysteine-rich transmembrane module containing 1 -0.0201132
ATRN attractin -0.0200816
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.019988
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 -0.0199038
NFX1 nuclear transcription factor, X-box binding 1 -0.0198599
PGAP1 post-GPI attachment to proteins 1 -0.0197832
FAM177A1 family with sequence similarity 177, member A1 -0.0197759
SRSF4 serine/arginine-rich splicing factor 4 -0.0197726
ZMYND8 zinc finger, MYND-type containing 8 -0.0197663
CADPS2 Ca++-dependent secretion activator 2 -0.0197358
PROCR protein C receptor, endothelial -0.019717
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0196829
ADIPOR2 adiponectin receptor 2 -0.0196752
RPS29 ribosomal protein S29 -0.0196686
RASA2 RAS p21 protein activator 2 -0.0195681
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -0.0195673
GSK3B glycogen synthase kinase 3 beta -0.0195613
USP32 ubiquitin specific peptidase 32 -0.0195371
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0194034
ETF1 eukaryotic translation termination factor 1 -0.0193804
SOAT1 sterol O-acyltransferase 1 -0.0193576
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0193436
LDLR low density lipoprotein receptor -0.0193375
RANBP2 RAN binding protein 2 -0.0193124
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.0192926
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0192797
UNK unkempt family zinc finger -0.0192496
FCGBP Fc fragment of IgG binding protein -0.0192177
RASEF RAS and EF-hand domain containing -0.0191814
VPS50 VPS50 subunit of EARP/GARPII complex -0.019143
IQGAP2 IQ motif containing GTPase activating protein 2 -0.0191394
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.0191087
MFF mitochondrial fission factor -0.0191057
KDM3B lysine (K)-specific demethylase 3B -0.0190988
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.0190614
NINL ninein-like -0.0190461
ZMYM4 zinc finger, MYM-type 4 -0.0190422
JUP junction plakoglobin -0.018977
SLC49A4 solute carrier family 49 member 4 -0.0189007
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.018883
DYM dymeclin -0.018724
EZR ezrin -0.01869
AFF1 AF4/FMR2 family, member 1 -0.0186497
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -0.0186447
RPS18 ribosomal protein S18 -0.0186035
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0185552
HBP1 HMG-box transcription factor 1 -0.0184873
STRN3 striatin, calmodulin binding protein 3 -0.0184525
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0184505
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0184154
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0183941
PLAUR plasminogen activator, urokinase receptor -0.0183588
PRRC2C proline-rich coiled-coil 2C -0.0183509
ITGAV integrin, alpha V -0.0183447
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.0183333
ATG7 autophagy related 7 -0.0183325
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0182716
CD46 CD46 molecule, complement regulatory protein -0.0181568
SERINC5 serine incorporator 5 -0.018142
OLA1 Obg-like ATPase 1 -0.0181046
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -0.0180768
MACF1 microtubule-actin crosslinking factor 1 -0.0180754
CFLAR CASP8 and FADD-like apoptosis regulator -0.0180684
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0179814
PM20D1 peptidase M20 domain containing 1 -0.0178809
HIPK3 homeodomain interacting protein kinase 3 -0.017872
CHD6 chromodomain helicase DNA binding protein 6 -0.0178715
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.0177672
FSTL4 follistatin-like 4 -0.0177576
SHISA5 shisa family member 5 -0.0177287
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.017702
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.0176836
CTPS2 CTP synthase 2 -0.0176695
TOM1L1 target of myb1 (chicken)-like 1 -0.0176693
TNS4 tensin 4 -0.0176352
TRAF3 TNF receptor-associated factor 3 -0.0176332
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0175932
IGFBP3 insulin-like growth factor binding protein 3 -0.0175889
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -0.0175601
CAMK2D calcium/calmodulin-dependent protein kinase II delta -0.0175493
ADAM17 ADAM metallopeptidase domain 17 -0.0175415
PLIN4 perilipin 4 -0.0175328
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0175144
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.017514
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -0.0174335
LMTK2 lemur tyrosine kinase 2 -0.0174194
TM4SF1 transmembrane 4 L six family member 1 -0.0174119
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 -0.0174095
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0174018
NCOA2 nuclear receptor coactivator 2 -0.0173286
CEP290 centrosomal protein 290kDa -0.0172933
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.017287
FXYD2 FXYD domain containing ion transport regulator 2 -0.0172471
FAM135A family with sequence similarity 135, member A -0.0172343
SKIL SKI-like proto-oncogene -0.0172098
PLD3 phospholipase D family, member 3 -0.0171818
RANBP17 RAN binding protein 17 -0.0171738
AKAP9 A kinase (PRKA) anchor protein 9 -0.0171299
TRIM33 tripartite motif containing 33 -0.0170937
TRIM16 tripartite motif containing 16 -0.0170225
H1-10 H1.10 linker histone -0.0170159
STIP1 stress-induced phosphoprotein 1 -0.0170132
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0169896
PNISR PNN-interacting serine/arginine-rich protein -0.0169682
LRP10 low density lipoprotein receptor-related protein 10 -0.0169557
SEPTIN11 septin 11 -0.0169304
ACER3 alkaline ceramidase 3 -0.0169263
SDC1 syndecan 1 -0.0169181
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0169158
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.0168895
INO80 INO80 complex subunit -0.016884
BCLAF3 BCLAF1 and THRAP3 family member 3 -0.0168643
BIRC6 baculoviral IAP repeat containing 6 -0.0168182
RAB1A RAB1A, member RAS oncogene family -0.0168118
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -0.016786
TASP1 taspase, threonine aspartase, 1 -0.0167857
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0167659
CATSPERB catsper channel auxiliary subunit beta -0.0167505
SCFD1 sec1 family domain containing 1 -0.0167467
WDR75 WD repeat domain 75 -0.0167341
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -0.01673
KDM5B lysine (K)-specific demethylase 5B -0.0166735
SFTPA2 surfactant protein A2 -0.016659
PTPRF protein tyrosine phosphatase, receptor type, F -0.0166213
REV1 REV1, polymerase (DNA directed) -0.0166021
RPSA ribosomal protein SA -0.0166018
DAZAP2 DAZ associated protein 2 -0.0165758
TRA2A transformer 2 alpha homolog (Drosophila) -0.0165729
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.0165527
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0165336
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -0.0165225
TMED9 transmembrane emp24 protein transport domain containing 9 -0.0164939
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0164925
COXFA4 cytochrome c oxidase associated subunit FA4 -0.0164925
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -0.0164848
FAT1 FAT atypical cadherin 1 -0.0164212
SMIM14 small integral membrane protein 14 -0.0164161
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -0.0163861
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.01638
FTH1 ferritin, heavy polypeptide 1 -0.0163494
RPN2 ribophorin II -0.016275
ANKH ANKH inorganic pyrophosphate transport regulator -0.0162278
LAPTM4B lysosomal protein transmembrane 4 beta -0.0162259
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.0161697
ARHGAP12 Rho GTPase activating protein 12 -0.0161493
SLC22A23 solute carrier family 22, member 23 -0.016147
PPIA peptidylprolyl isomerase A (cyclophilin A) -0.0161455
ATG10 autophagy related 10 -0.0161287
WDR41 WD repeat domain 41 -0.0160384
PITPNA phosphatidylinositol transfer protein, alpha -0.0160054
SLC38A1 solute carrier family 38, member 1 -0.0159992
GNB5 guanine nucleotide binding protein (G protein), beta 5 -0.0159594
CHGB chromogranin B -0.0159429
SEC23A Sec23 homolog A (S. cerevisiae) -0.0158563
RPL8 ribosomal protein L8 -0.0158528
PCBP2 poly(rC) binding protein 2 -0.015821
NAP1L1 nucleosome assembly protein 1-like 1 -0.015808
EPN2 epsin 2 -0.0157991
IREB2 iron-responsive element binding protein 2 -0.0157968
STXBP1 syntaxin binding protein 1 -0.015738
TOM1L2 target of myb1-like 2 (chicken) -0.015734
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0157127
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -0.0156433
WDR59 WD repeat domain 59 -0.0156278
BCLAF1 BCL2-associated transcription factor 1 -0.0155814
TPD52 tumor protein D52 -0.0155569
PKM pyruvate kinase, muscle -0.0155469
WDR20 WD repeat domain 20 -0.0155436
FTSJ3 FtsJ homolog 3 (E. coli) -0.0155187
PDIA4 protein disulfide isomerase family A, member 4 -0.015516
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0155031
G6PC3 glucose 6 phosphatase, catalytic, 3 -0.0154905
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0154642
SLC45A4 solute carrier family 45, member 4 -0.0154589
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -0.015454
RRBP1 ribosome binding protein 1 -0.0154271
PCCA propionyl CoA carboxylase, alpha polypeptide -0.0154207
RETREG3 reticulophagy regulator family member 3 -0.0154149
SRRM1 serine/arginine repetitive matrix 1 -0.0154098
TM9SF2 transmembrane 9 superfamily member 2 -0.0153784
PCNT pericentrin -0.0153634
CCDC186 coiled-coil domain containing 186 -0.0153628
CCS copper chaperone for superoxide dismutase -0.0153587
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0153362
SPRED1 sprouty-related, EVH1 domain containing 1 -0.0153195
OGA O-GlcNAcase -0.0153071
RPS16 ribosomal protein S16 -0.0152762
GRAMD1A GRAM domain containing 1A -0.0152549
HLA-DMB major histocompatibility complex, class II, DM beta -0.0152443
SMOC1 SPARC related modular calcium binding 1 -0.0152393
AMBRA1 autophagy/beclin-1 regulator 1 -0.0151969
RFX7 regulatory factor X, 7 -0.0151788
SIGMAR1 sigma non-opioid intracellular receptor 1 -0.0151766
KIF13A kinesin family member 13A -0.0150473
PER2 period circadian clock 2 -0.0150191
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0150127
LMBR1 limb development membrane protein 1 -0.0149891
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -0.0149826
ERRFI1 ERBB receptor feedback inhibitor 1 -0.014947
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.0149382
RALY RALY heterogeneous nuclear ribonucleoprotein -0.014929
ALPK2 alpha-kinase 2 -0.0148142
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.0147966
MPZL1 myelin protein zero-like 1 -0.0147895
KIFBP kinesin family binding protein -0.0147875
SANBR SANT and BTB domain regulator of CSR -0.014741
TCTN3 tectonic family member 3 -0.0146479
TSG101 tumor susceptibility 101 -0.0146229
TENT2 terminal nucleotidyltransferase 2 -0.0146156
UROS uroporphyrinogen III synthase -0.0145851
KLHL5 kelch-like family member 5 -0.0145625
ECH1 enoyl CoA hydratase 1, peroxisomal -0.0145595
HDLBP high density lipoprotein binding protein -0.0145532
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -0.014547
RTN4RL2 reticulon 4 receptor-like 2 -0.014512
FBXL17 F-box and leucine-rich repeat protein 17 -0.0144922
NCOA6 nuclear receptor coactivator 6 -0.0144663
RB1 retinoblastoma 1 -0.0144477
PCYOX1 prenylcysteine oxidase 1 -0.0144475
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0144405
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0144372
MACO1 macoilin 1 -0.0143696
DSTYK dual serine/threonine and tyrosine protein kinase -0.0143634
CCSER2 coiled-coil serine-rich protein 2 -0.0143268
FUBP3 far upstream element (FUSE) binding protein 3 -0.0142659
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.0142201
CPEB2 cytoplasmic polyadenylation element binding protein 2 -0.0142175
AARS1 alanyl-tRNA synthetase 1 -0.0142075
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.0142048
FPGS folylpolyglutamate synthase -0.0141512
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.0141168
SBNO1 strawberry notch homolog 1 (Drosophila) -0.0141141
DARS1 aspartyl-tRNA synthetase 1 -0.0141072
RARS1 arginyl-tRNA synthetase 1 -0.0140894
AVPI1 arginine vasopressin-induced 1 -0.0140874
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -0.0140682
MEGF8 multiple EGF-like-domains 8 -0.0140462
RBM5 RNA binding motif protein 5 -0.0140347
ZFAND5 zinc finger, AN1-type domain 5 -0.0140192
WIPF1 WAS/WASL interacting protein family, member 1 -0.0140095
ABHD12 abhydrolase domain containing 12 -0.0140074
RESF1 retroelement silencing factor 1 -0.013995
GPRC5C G protein-coupled receptor, class C, group 5, member C -0.0139775
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.0139741