A549_Valproic acid sodium salt_100nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 100nM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_Valproic acid sodium salt_100nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.14482
KRT8 keratin 8, type II 0.141348
RAB10 RAB10, member RAS oncogene family 0.133107
KRT18 keratin 18, type I 0.109387
MYO1E myosin IE 0.107711
ACTN4 actinin, alpha 4 0.0875473
ENO1 enolase 1, (alpha) 0.0819348
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0726913
RBM47 RNA binding motif protein 47 0.0691272
AKR1C3 aldo-keto reductase family 1, member C3 0.0671827
PKM pyruvate kinase, muscle 0.0668761
CELF1 CUGBP, Elav-like family member 1 0.0666126
AKR1C2 aldo-keto reductase family 1, member C2 0.0636858
TBC1D5 TBC1 domain family, member 5 0.0610309
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0609022
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.0601586
GPC6 glypican 6 0.0587765
DOCK5 dedicator of cytokinesis 5 0.0571232
ABTB3 ankyrin repeat and BTB domain containing 3 0.0548566
TMCC1 transmembrane and coiled-coil domain family 1 0.0547936
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.0522715
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0449529
PTPRM protein tyrosine phosphatase, receptor type, M 0.0446528
NT5C2 5'-nucleotidase, cytosolic II 0.0444503
ACACA acetyl-CoA carboxylase alpha 0.0443674
PDE4D phosphodiesterase 4D, cAMP-specific 0.0434197
UBASH3B ubiquitin associated and SH3 domain containing B 0.0428409
SPIDR scaffolding protein involved in DNA repair 0.0424209
EFNA5 ephrin-A5 0.0411876
USP32 ubiquitin specific peptidase 32 0.0408924
GRB2 growth factor receptor-bound protein 2 0.0407597
MEIS2 Meis homeobox 2 0.040094
RPLP1 ribosomal protein, large, P1 0.0383619
CYRIB CYFIP related Rac1 interactor B 0.037296
PDE4B phosphodiesterase 4B, cAMP-specific 0.0372694
EXOC4 exocyst complex component 4 0.0364863
PUM3 pumilio RNA binding family member 3 0.0356645
GAB2 GRB2-associated binding protein 2 0.0356515
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0350491
NFIA nuclear factor I/A 0.0347537
VCP valosin containing protein 0.0346579
ANXA4 annexin A4 0.0341793
SRSF4 serine/arginine-rich splicing factor 4 0.0341222
MED13L mediator complex subunit 13-like 0.0341009
SLC39A11 solute carrier family 39, member 11 0.0340239
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0334988
KYNU kynureninase 0.0334899
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.0332157
RFWD3 ring finger and WD repeat domain 3 0.0331257
NSD2 nuclear receptor binding SET domain protein 2 0.0323609
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0322083
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0317826
COL5A2 collagen, type V, alpha 2 0.031701
PDS5A PDS5 cohesin associated factor A 0.0313593
MTA3 metastasis associated 1 family, member 3 0.0313484
LRP1B low density lipoprotein receptor-related protein 1B 0.031198
ANKRD17 ankyrin repeat domain 17 0.031145
CUEDC1 CUE domain containing 1 0.0309685
FLNB filamin B, beta 0.0306318
MYOF myoferlin 0.0300392
HDAC4 histone deacetylase 4 0.0298712
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.0297937
HDAC8 histone deacetylase 8 0.0295652
MPRIP myosin phosphatase Rho interacting protein 0.0295645
CUL3 cullin 3 0.0294318
RABL6 RAB, member RAS oncogene family-like 6 0.029427
GSE1 Gse1 coiled-coil protein 0.028845
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0287673
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0287589
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.0287336
MRPS27 mitochondrial ribosomal protein S27 0.0287303
MPG N-methylpurine-DNA glycosylase 0.0283406
MYO9B myosin IXB 0.0283267
CDIN1 CDAN1 interacting nuclease 1 0.0282321
NPTN neuroplastin 0.0281038
ARHGAP11B Rho GTPase activating protein 11B 0.0280746
SMC4 structural maintenance of chromosomes 4 0.0278138
OSBPL10 oxysterol binding protein-like 10 0.0275281
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0271239
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.027031
THADA thyroid adenoma associated 0.0267922
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.0266276
LIN52 lin-52 DREAM MuvB core complex component 0.0264958
PARD3 par-3 family cell polarity regulator 0.0264014
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.0262378
AHCTF1 AT hook containing transcription factor 1 0.026195
EXT1 exostosin glycosyltransferase 1 0.0261437
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.0261398
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0260389
GPATCH8 G patch domain containing 8 0.0260192
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.0257188
CARMIL1 capping protein regulator and myosin 1 linker 1 0.0256733
SET SET nuclear proto-oncogene 0.0256034
PRKCE protein kinase C, epsilon 0.025413
TENT4B terminal nucleotidyltransferase 4B 0.0254128
PHGDH phosphoglycerate dehydrogenase 0.0253435
PELP1 proline, glutamate and leucine rich protein 1 0.0253245
FHIP2A FHF complex subunit HOOK interacting protein 2A 0.0251446
DIAPH1 diaphanous-related formin 1 0.0250339
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0250314
DPP8 dipeptidyl-peptidase 8 0.0249595
PCSK7 proprotein convertase subtilisin/kexin type 7 0.0249519
CEP350 centrosomal protein 350kDa 0.0249512
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0247379
TCF12 transcription factor 12 0.0245538
CEP112 centrosomal protein 112kDa 0.0244578
AFAP1 actin filament associated protein 1 0.0244405
FOXK1 forkhead box K1 0.0244083
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.0242512
DNM2 dynamin 2 0.0239513
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0239383
DIDO1 death inducer-obliterator 1 0.0238916
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.023761
AKR1C1 aldo-keto reductase family 1, member C1 0.023578
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.023432
TGIF1 TGFB-induced factor homeobox 1 0.0233867
DSCAM Down syndrome cell adhesion molecule 0.0233298
TUBB tubulin, beta class I 0.0233198
ARRB1 arrestin, beta 1 0.0233074
KLHDC10 kelch domain containing 10 0.0232894
EREG epiregulin 0.0232543
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.0230811
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.0230115
CHD4 chromodomain helicase DNA binding protein 4 0.0228375
BICC1 BicC family RNA binding protein 1 0.0228328
ABHD3 abhydrolase domain containing 3 0.0228253
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.0228228
KIAA0753 KIAA0753 0.0228051
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0227731
STAG2 stromal antigen 2 0.0227445
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0227347
SENP6 SUMO1/sentrin specific peptidase 6 0.0226653
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.0226253
BBX bobby sox homolog (Drosophila) 0.02255
MSI2 musashi RNA-binding protein 2 0.0224639
ARL8B ADP-ribosylation factor-like 8B 0.0223671
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0222993
MINK1 misshapen-like kinase 1 0.0222377
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.0222342
PRRC2C proline-rich coiled-coil 2C 0.0222064
PARD6B par-6 family cell polarity regulator beta 0.022201
KLF5 Kruppel-like factor 5 (intestinal) 0.0221166
TMF1 TATA element modulatory factor 1 0.0220798
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0220788
ITGAV integrin, alpha V 0.022035
ZDHHC20 zinc finger, DHHC-type containing 20 0.0219747
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.0218115
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.0216999
S100A11 S100 calcium binding protein A11 0.0214964
POLK polymerase (DNA directed) kappa 0.0214904
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 0.0214687
PHACTR4 phosphatase and actin regulator 4 0.0214204
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.0214119
PALLD palladin, cytoskeletal associated protein 0.021338
RHOA ras homolog family member A 0.0212962
LDLR low density lipoprotein receptor 0.0212581
JARID2 jumonji, AT rich interactive domain 2 0.0211744
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0211447
ERH enhancer of rudimentary homolog (Drosophila) 0.0210697
SYNJ2BP synaptojanin 2 binding protein 0.0210591
CCAR1 cell division cycle and apoptosis regulator 1 0.0209301
SMAD3 SMAD family member 3 0.0208905
ANXA1 annexin A1 0.0207577
RASA2 RAS p21 protein activator 2 0.0206769
ELP2 elongator acetyltransferase complex subunit 2 0.0206363
MTIF2 mitochondrial translational initiation factor 2 0.020548
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.0205412
EVI5 ecotropic viral integration site 5 0.0205256
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.0205239
KIF2A kinesin heavy chain member 2A 0.0204994
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0204862
AGFG1 ArfGAP with FG repeats 1 0.0204672
AFF1 AF4/FMR2 family, member 1 0.0204632
FAF1 Fas (TNFRSF6) associated factor 1 0.0204619
HELB helicase (DNA) B 0.0204464
MED27 mediator complex subunit 27 0.0204145
RAI1 retinoic acid induced 1 0.0203857
NBDY negative regulator of P-body association 0.0203416
SUSD1 sushi domain containing 1 0.0203028
ALMS1 Alstrom syndrome protein 1 0.0202885
BCAS3 breast carcinoma amplified sequence 3 0.0202822
BRCA1 breast cancer 1, early onset 0.0202751
AMBRA1 autophagy/beclin-1 regulator 1 0.020235
CDK6 cyclin-dependent kinase 6 0.0201558
CNN2 calponin 2 0.0199103
IL6ST interleukin 6 signal transducer 0.019881
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.019858
CENPF centromere protein F, 350/400kDa 0.0197904
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.0197475
RPL30 ribosomal protein L30 0.0197086
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.0196816
NDC1 NDC1 transmembrane nucleoporin 0.0196011
CPLX2 complexin 2 0.0195464
FYCO1 FYVE and coiled-coil domain containing 1 0.0195006
KIAA1671 KIAA1671 0.0194667
HSPH1 heat shock 105kDa/110kDa protein 1 0.0194632
SEC16A SEC16 homolog A (S. cerevisiae) 0.0194613
COP1 COP1 E3 ubiquitin ligase 0.0194009
IPO5 importin 5 0.0193587
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0192786
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0192553
LDHB lactate dehydrogenase B 0.0192462
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0192461
DOK4 docking protein 4 0.0191313
S100A10 S100 calcium binding protein A10 0.0191258
ZC3H4 zinc finger CCCH-type containing 4 0.0191258
AFTPH aftiphilin 0.0191101
XPO1 exportin 1 0.019088
GCLC glutamate-cysteine ligase, catalytic subunit 0.0190832
ZFYVE9 zinc finger, FYVE domain containing 9 0.0190557
TMEM164 transmembrane protein 164 0.0189891
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.0189271
VIRMA vir like m6A methyltransferase associated 0.0188778
TMEM168 transmembrane protein 168 0.0188408
WNK1 WNK lysine deficient protein kinase 1 0.0188162
LARP4B La ribonucleoprotein domain family, member 4B 0.0187964
MDN1 MDN1, midasin homolog (yeast) 0.0187783
PTMS parathymosin 0.0187666
NPAS2 neuronal PAS domain protein 2 0.0187637
KRIT1 KRIT1, ankyrin repeat containing 0.0187297
SIK2 salt-inducible kinase 2 0.018676
PGK1 phosphoglycerate kinase 1 0.0186501
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0186178
EXOC6B exocyst complex component 6B 0.0185818
SPRED2 sprouty-related, EVH1 domain containing 2 0.0185551
ZCCHC14 zinc finger, CCHC domain containing 14 0.018542
FAF2 Fas associated factor family member 2 0.0185034
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0184185
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.0182795
TUBA1B tubulin, alpha 1b 0.0182718
LCORL ligand dependent nuclear receptor corepressor-like 0.0182639
ZBTB11 zinc finger and BTB domain containing 11 0.0182612
AFG2A AFG2 AAA ATPase homolog A 0.0182586
ZNF236 zinc finger protein 236 0.0182303
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.0182177
ELOVL5 ELOVL fatty acid elongase 5 0.0182176
DOCK10 dedicator of cytokinesis 10 0.018212
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0181823
DPP3 dipeptidyl-peptidase 3 0.018177
METTL2B methyltransferase like 2B 0.018121
HOOK3 hook microtubule-tethering protein 3 0.0180917
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0180359
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0180213
ANLN anillin, actin binding protein 0.0179717
BPTF bromodomain PHD finger transcription factor 0.017938
DNMBP dynamin binding protein 0.0179347
DHCR24 24-dehydrocholesterol reductase 0.0178079
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0177332
ATF7IP2 activating transcription factor 7 interacting protein 2 0.0176727
IQSEC2 IQ motif and Sec7 domain 2 0.0176498
BTBD7 BTB (POZ) domain containing 7 0.0176302
CENPP centromere protein P 0.0176171
DARS1 aspartyl-tRNA synthetase 1 0.0175808
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.017561
KDM2A lysine (K)-specific demethylase 2A 0.0175452
MIPOL1 mirror-image polydactyly 1 0.0175359
YARS1 tyrosyl-tRNA synthetase 1 0.0175042
ATXN2 ataxin 2 0.0174464
PEAK1 pseudopodium-enriched atypical kinase 1 0.0174348
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.0174024
ABLIM1 actin binding LIM protein 1 0.0173983
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0173567
DCAF7 DDB1 and CUL4 associated factor 7 0.0173374
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0172884
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.0172596
COPE coatomer protein complex, subunit epsilon 0.0172541
ITFG2 integrin alpha FG-GAP repeat containing 2 0.0172455
TPI1 triosephosphate isomerase 1 0.0172196
LGALS3 lectin, galactoside-binding, soluble, 3 0.0172088
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 0.017196
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0171528
ZMYND8 zinc finger, MYND-type containing 8 0.0171176
NLK nemo-like kinase 0.0171099
CAMKMT calmodulin-lysine N-methyltransferase 0.0170851
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.0170532
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.0170199
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0169869
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 0.0169743
LIN54 lin-54 DREAM MuvB core complex component 0.0169583
CCND3 cyclin D3 0.0168665
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0168608
BSG basigin (Ok blood group) 0.0168221
SREBF2 sterol regulatory element binding transcription factor 2 0.0168081
SUFU suppressor of fused homolog (Drosophila) 0.016805
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0167862
MASTL microtubule associated serine/threonine kinase-like 0.0167856
KIAA1549 KIAA1549 0.0167853
CORO1B coronin, actin binding protein, 1B 0.0167271
RPL19 ribosomal protein L19 0.0167162
RSRC1 arginine/serine-rich coiled-coil 1 0.0167019
PAWR PRKC, apoptosis, WT1, regulator 0.0166958
DTNB dystrobrevin, beta 0.0166027
CDC42SE2 CDC42 small effector 2 0.0165873
GATAD2B GATA zinc finger domain containing 2B 0.0165666
GPATCH4 G patch domain containing 4 0.0165317
CANT1 calcium activated nucleotidase 1 0.0165045
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0164427
APIP APAF1 interacting protein 0.0163096
AREG amphiregulin 0.0162891
RAB3IP RAB3A interacting protein 0.0162455
MAML3 mastermind-like 3 (Drosophila) 0.0162364
ETV6 ets variant 6 0.0162182
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0162125
ARHGAP18 Rho GTPase activating protein 18 0.0162112
KIAA1217 KIAA1217 0.0162086
USP22 ubiquitin specific peptidase 22 0.0161577
STK38 serine/threonine kinase 38 0.0161053
GPBP1 GC-rich promoter binding protein 1 0.0160972
RMDN1 regulator of microtubule dynamics 1 0.0160778
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0160722
TULP4 tubby like protein 4 0.0159881
HOMER1 homer scaffolding protein 1 0.0159767
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0159256
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0159016
RPH3AL rabphilin 3A-like (without C2 domains) 0.0158628
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0158566
NUDC nudC nuclear distribution protein 0.0158538
COX7C cytochrome c oxidase subunit VIIc 0.0158375
JADE3 jade family PHD finger 3 0.015768
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0157505
SLC38A6 solute carrier family 38, member 6 0.0156656
TPM3 tropomyosin 3 0.0156639
RBL1 retinoblastoma-like 1 0.0156625
PANK2 pantothenate kinase 2 0.015638
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0156016
VGLL4 vestigial-like family member 4 0.0156
ZNHIT6 zinc finger, HIT-type containing 6 0.0155943
KIAA1958 KIAA1958 0.0155781
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0155299
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0155057
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0154846
ATAD2 ATPase family, AAA domain containing 2 0.0154561
SCARB1 scavenger receptor class B, member 1 0.0154534
AKAP10 A kinase (PRKA) anchor protein 10 0.0154491
GPATCH2L G patch domain containing 2-like 0.0154369
ADCY9 adenylate cyclase 9 0.0154142
FOXM1 forkhead box M1 0.015392
CUL2 cullin 2 0.0153871
EYA4 EYA transcriptional coactivator and phosphatase 4 0.01536
TSPAN15 tetraspanin 15 0.015357
METTL8 methyltransferase like 8 0.0153548
KDM1A lysine (K)-specific demethylase 1A 0.015346
TCERG1 transcription elongation regulator 1 0.0153285
FAM193A family with sequence similarity 193, member A 0.0153067
MYRF myelin regulatory factor 0.0152811
EIF3G eukaryotic translation initiation factor 3, subunit G 0.0152741
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0152601
MAST4 microtubule associated serine/threonine kinase family member 4 0.0152359
UBB ubiquitin B 0.0152174
TRAPPC9 trafficking protein particle complex 9 0.0152041
GFRA1 GDNF family receptor alpha 1 0.0151902
SAV1 salvador family WW domain containing protein 1 0.0151424
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.0151364
UXS1 UDP-glucuronate decarboxylase 1 0.0151089
TUSC3 tumor suppressor candidate 3 0.0150238
NUP205 nucleoporin 205kDa 0.0149637
CSNK1G2 casein kinase 1, gamma 2 0.0149436
ATP5F1D ATP synthase F1 subunit delta 0.0149119
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.0148788
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.0148723
ZNF195 zinc finger protein 195 0.0148696
CAMSAP1 calmodulin regulated spectrin-associated protein 1 0.0148685
NOP56 NOP56 ribonucleoprotein 0.0148669
LEMD3 LEM domain containing 3 0.0148565
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 0.0147871
ALCAM activated leukocyte cell adhesion molecule 0.0147844
MEF2D myocyte enhancer factor 2D 0.0147827
AVEN apoptosis, caspase activation inhibitor 0.0147717
TPST1 tyrosylprotein sulfotransferase 1 0.0147716
SEPTIN9 septin 9 0.0147659
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.0147653
PRPF8 pre-mRNA processing factor 8 0.014694
GXYLT1 glucoside xylosyltransferase 1 0.0146764
COPG2 coatomer protein complex, subunit gamma 2 0.0146665
KSR1 kinase suppressor of ras 1 0.0146624
ATP5F1B ATP synthase F1 subunit beta 0.0145638
FLII flightless I homolog (Drosophila) 0.0145629
WDFY1 WD repeat and FYVE domain containing 1 0.0145445
IFT172 intraflagellar transport 172 0.0145335
TPX2 TPX2, microtubule-associated 0.0145332
TSC22D2 TSC22 domain family, member 2 0.0144648
SIRT7 sirtuin 7 0.0144591
TRIM24 tripartite motif containing 24 0.0143489
SLC35F2 solute carrier family 35, member F2 0.0143488
ANKLE2 ankyrin repeat and LEM domain containing 2 0.0143408
INCENP inner centromere protein antigens 135/155kDa 0.0142922
DAPK1 death-associated protein kinase 1 0.0142788
CEP164 centrosomal protein 164kDa 0.0142739
SREBF1 sterol regulatory element binding transcription factor 1 0.0142689
EGFL7 EGF-like-domain, multiple 7 0.014255
MIA2 melanoma inhibitory activity 2 0.0142255
SETDB1 SET domain, bifurcated 1 0.014195
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.0141938
DCAKD dephospho-CoA kinase domain containing 0.0141802
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.0141727
ZNF680 zinc finger protein 680 0.0141478
CACUL1 CDK2-associated, cullin domain 1 0.0140849
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.0140615
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0140572
FRMD5 FERM domain containing 5 0.0140532
LY6E lymphocyte antigen 6 complex, locus E 0.0140217
CLIC4 chloride intracellular channel 4 0.0140206
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.0140048
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.0139926
CHD3 chromodomain helicase DNA binding protein 3 0.0139496
HIPK3 homeodomain interacting protein kinase 3 0.0139427
HOXB7 homeobox B7 0.0139272
WSB2 WD repeat and SOCS box containing 2 0.0139239
RUFY1 RUN and FYVE domain containing 1 0.0139238
DIAPH3 diaphanous-related formin 3 0.0139207
KIF3C kinesin family member 3C 0.0139127
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.0138941
KANK2 KN motif and ankyrin repeat domains 2 0.0138914
KCTD1 potassium channel tetramerization domain containing 1 0.0138914
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 0.0138906
MEAK7 MTOR associated protein, eak-7 homolog 0.0138873
ANXA2 annexin A2 0.013885
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0138644
RNASEH1 ribonuclease H1 0.0138576
SIL1 SIL1 nucleotide exchange factor 0.0138486
ABHD2 abhydrolase domain containing 2 0.0138183
ACADVL acyl-CoA dehydrogenase, very long chain 0.0138006
SIRAL2 SIR2 antiphage like 2 0.0137922
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.0137776
STRBP spermatid perinuclear RNA binding protein 0.0137585
SCFD2 sec1 family domain containing 2 0.0137346
RPS20 ribosomal protein S20 0.0137147
INVS inversin 0.0137139
WARS1 tryptophanyl-tRNA synthetase 1 0.0136766
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.0136711
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase 0.0136638
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.0136345
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.0136281
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.0136146
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.013601
TBC1D10A TBC1 domain family, member 10A 0.0135951
HS1BP3 HCLS1 binding protein 3 0.0135824
TLK1 tousled-like kinase 1 0.0135559
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.0135456
SPAG9 sperm associated antigen 9 0.0135411
BANP BTG3 associated nuclear protein 0.0135109
RBBP6 retinoblastoma binding protein 6 0.0135056
SAE1 SUMO1 activating enzyme subunit 1 0.013504
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.0134996
AGK acylglycerol kinase 0.0134867
KMT2C lysine (K)-specific methyltransferase 2C 0.0134734
ETF1 eukaryotic translation termination factor 1 0.0134641
CFLAR CASP8 and FADD-like apoptosis regulator 0.013419
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0134058
CFAP44 cilia and flagella associated protein 44 0.013386
RAD18 RAD18 E3 ubiquitin protein ligase 0.0133793
XYLT2 xylosyltransferase II 0.0133612
MGST3 microsomal glutathione S-transferase 3 0.0133566
KIF21A kinesin family member 21A 0.0133551
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.0133495
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.0133448
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0133332
NARS1 asparaginyl-tRNA synthetase 1 0.0133149
WDR35 WD repeat domain 35 0.0133069
CCNF cyclin F 0.0133036
FNBP4 formin binding protein 4 0.0133011
CAPN7 calpain 7 0.0132981
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.0132882
YBX3 Y box binding protein 3 0.0132832
TUBB4B tubulin, beta 4B class IVb 0.0132826
PCM1 pericentriolar material 1 0.013271
MICU2 mitochondrial calcium uptake 2 0.0132618
CARM1 coactivator-associated arginine methyltransferase 1 0.0132567
CEP128 centrosomal protein 128kDa 0.0132425
CENPE centromere protein E, 312kDa 0.013232
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0132242
KLHL42 kelch-like family member 42 0.0132169
SNX5 sorting nexin 5 0.0132144
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.013203
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.0132005
LCLAT1 lysocardiolipin acyltransferase 1 0.0131834
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.0131781
BRCA2 breast cancer 2, early onset 0.0131747
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0131681
MANBA mannosidase, beta A, lysosomal 0.0131536
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.0131463
YTHDC2 YTH domain containing 2 0.013139
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.013111
EIF4E eukaryotic translation initiation factor 4E 0.0131042
MLEC malectin 0.0130954
CDC7 cell division cycle 7 0.0130911
CDC16 cell division cycle 16 0.0130764
VAV2 vav 2 guanine nucleotide exchange factor 0.013057
CAPN1 calpain 1, (mu/I) large subunit 0.0130564
GLI2 GLI family zinc finger 2 0.0130445
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.0130402
ALG12 ALG12, alpha-1,6-mannosyltransferase 0.0130224
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.0129999
INTS3 integrator complex subunit 3 0.0129953
IQGAP2 IQ motif containing GTPase activating protein 2 0.0129848
MAP2K1 mitogen-activated protein kinase kinase 1 0.012941
USP9X ubiquitin specific peptidase 9, X-linked 0.0129364
EPDR1 ependymin related 1 0.0129319
HCFC1 host cell factor C1 0.012931
ADCY8 adenylate cyclase 8 (brain) 0.0129096

decreased expression

Symbol Name Standardized Value
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.110439
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.101743
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.089776
JMJD1C jumonji domain containing 1C -0.0869822
TXNRD1 thioredoxin reductase 1 -0.0832447
EHBP1 EH domain binding protein 1 -0.0718786
PDE10A phosphodiesterase 10A -0.0655518
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.065371
IGFBP4 insulin-like growth factor binding protein 4 -0.0622986
NRG1 neuregulin 1 -0.0588818
ZBTB20 zinc finger and BTB domain containing 20 -0.0562677
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0559687
APP amyloid beta (A4) precursor protein -0.0537533
RRBP1 ribosome binding protein 1 -0.0536686
THSD7A thrombospondin, type I, domain containing 7A -0.053288
EZR ezrin -0.0511726
MUSK muscle, skeletal, receptor tyrosine kinase -0.0480452
WWOX WW domain containing oxidoreductase -0.0470147
HM13 histocompatibility (minor) 13 -0.0469426
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0467737
HIP1 huntingtin interacting protein 1 -0.0465027
ARL15 ADP-ribosylation factor-like 15 -0.0459456
LIMCH1 LIM and calponin homology domains 1 -0.0455255
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0453988
PTPRK protein tyrosine phosphatase, receptor type, K -0.0451412
STK24 serine/threonine kinase 24 -0.0450718
PTGR1 prostaglandin reductase 1 -0.0444343
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.0439252
MTUS1 microtubule associated tumor suppressor 1 -0.0428766
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0425809
TPM4 tropomyosin 4 -0.0420308
SH3D19 SH3 domain containing 19 -0.041821
GSK3B glycogen synthase kinase 3 beta -0.0408294
PLAUR plasminogen activator, urokinase receptor -0.0405868
LPP LIM domain containing preferred translocation partner in lipoma -0.0405061
EML4 echinoderm microtubule associated protein like 4 -0.0404306
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0399276
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0397608
SH3RF1 SH3 domain containing ring finger 1 -0.0395171
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0392412
VCL vinculin -0.0391454
MLPH melanophilin -0.0391215
RBM6 RNA binding motif protein 6 -0.0390218
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.038772
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0387516
ADNP activity-dependent neuroprotector homeobox -0.0384796
PATJ PATJ crumbs cell polarity complex component -0.0384107
GLIS3 GLIS family zinc finger 3 -0.0381342
DOCK1 dedicator of cytokinesis 1 -0.0378777
TAOK1 TAO kinase 1 -0.0373943
PCYOX1 prenylcysteine oxidase 1 -0.0372816
KDM3B lysine (K)-specific demethylase 3B -0.0371097
FMNL2 formin-like 2 -0.0370406
MRPL13 mitochondrial ribosomal protein L13 -0.0368046
ZNF638 zinc finger protein 638 -0.0367163
SMAD2 SMAD family member 2 -0.0363642
MYADM myeloid-associated differentiation marker -0.0362846
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0362639
VIM vimentin -0.0362034
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.036133
GPX2 glutathione peroxidase 2 -0.0360707
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0357978
ARHGAP26 Rho GTPase activating protein 26 -0.0357603
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0356975
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.035229
VMP1 vacuole membrane protein 1 -0.0350482
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.0347805
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0347788
TAOK3 TAO kinase 3 -0.0346199
CANX calnexin -0.0342397
POLR1A polymerase (RNA) I polypeptide A, 194kDa -0.034202
MYO1D myosin ID -0.0341571
DHDDS dehydrodolichyl diphosphate synthase -0.0337354
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0337307
SLC38A2 solute carrier family 38, member 2 -0.033658
NUP160 nucleoporin 160kDa -0.0335713
TBC1D14 TBC1 domain family, member 14 -0.0335062
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0332914
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0332449
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 -0.0329769
FAM222B family with sequence similarity 222, member B -0.0329427
NCOA2 nuclear receptor coactivator 2 -0.0329182
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0328635
CDK13 cyclin-dependent kinase 13 -0.0327064
RPS16 ribosomal protein S16 -0.0326974
FAM107B family with sequence similarity 107, member B -0.0326457
PTPRA protein tyrosine phosphatase, receptor type, A -0.0326357
ICE2 interactor of little elongation complex ELL subunit 2 -0.0326059
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0325081
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -0.0321883
CLU clusterin -0.0319125
AK1 adenylate kinase 1 -0.0318583
KIAA0319L KIAA0319-like -0.0316446
CP ceruloplasmin (ferroxidase) -0.0315579
RACK1 receptor for activated C kinase 1 -0.0314543
TNRC6B trinucleotide repeat containing 6B -0.031431
RPL32 ribosomal protein L32 -0.0312869
SUMF1 sulfatase modifying factor 1 -0.0310286
AKAP12 A kinase (PRKA) anchor protein 12 -0.0310071
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 -0.0309654
USP34 ubiquitin specific peptidase 34 -0.0307785
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.030457
BMPR1B bone morphogenetic protein receptor, type IB -0.0303869
MED13 mediator complex subunit 13 -0.0302669
RIN2 Ras and Rab interactor 2 -0.030068
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0300541
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0298364
CNTNAP3B contactin associated protein-like 3B -0.0296748
EPS8 epidermal growth factor receptor pathway substrate 8 -0.029523
MACROH2A1 macroH2A.1 histone -0.0291711
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0291639
USP15 ubiquitin specific peptidase 15 -0.0290792
PUM1 pumilio RNA-binding family member 1 -0.0290771
PHACTR2 phosphatase and actin regulator 2 -0.028979
SP3 Sp3 transcription factor -0.028676
HDLBP high density lipoprotein binding protein -0.0285627
KANK1 KN motif and ankyrin repeat domains 1 -0.0283372
TRPM7 transient receptor potential cation channel, subfamily M, member 7 -0.02833
PLPP1 phospholipid phosphatase 1 -0.0283186
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0282173
FHIT fragile histidine triad -0.028047
NTN4 netrin 4 -0.0278109
MAVS mitochondrial antiviral signaling protein -0.0277923
ZNF609 zinc finger protein 609 -0.0277668
PHF21A PHD finger protein 21A -0.0276654
RPS29 ribosomal protein S29 -0.0275164
USP3 ubiquitin specific peptidase 3 -0.0274769
TNPO1 transportin 1 -0.0274639
SPATS2 spermatogenesis associated, serine-rich 2 -0.027442
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -0.0274409
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0271419
FBXL17 F-box and leucine-rich repeat protein 17 -0.0270562
TGFBI transforming growth factor, beta-induced, 68kDa -0.0270539
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0269707
CTSD cathepsin D -0.0269556
TMEM41B transmembrane protein 41B -0.026518
EVA1C eva-1 homolog C (C. elegans) -0.0263273
FNDC3B fibronectin type III domain containing 3B -0.0262806
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.0262327
RPS19 ribosomal protein S19 -0.0262039
LRP10 low density lipoprotein receptor-related protein 10 -0.0261305
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0260583
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 -0.0258447
RPL27A ribosomal protein L27a -0.0258362
MBNL1 muscleblind-like splicing regulator 1 -0.0257744
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0257345
SLTM SAFB-like, transcription modulator -0.025617
GOLM2 golgi membrane protein 2 -0.0256156
TRIO trio Rho guanine nucleotide exchange factor -0.0256016
ZFHX3 zinc finger homeobox 3 -0.0255907
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0254725
ITCH itchy E3 ubiquitin protein ligase -0.0254711
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0254251
NMT1 N-myristoyltransferase 1 -0.0253537
NBAS neuroblastoma amplified sequence -0.0253498
SNAP25 synaptosomal-associated protein, 25kDa -0.0252388
SMOX spermine oxidase -0.0252049
MACROD2 MACRO domain containing 2 -0.0250908
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -0.0250576
BMPR1A bone morphogenetic protein receptor, type IA -0.0250156
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0248964
NRP1 neuropilin 1 -0.0247767
AUTS2 autism susceptibility candidate 2 -0.0247118
CLIP2 CAP-GLY domain containing linker protein 2 -0.0246773
GCLM glutamate-cysteine ligase, modifier subunit -0.0246165
CALR calreticulin -0.024583
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0245689
KAT6B K(lysine) acetyltransferase 6B -0.0245168
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -0.0244783
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.0242956
MKI67 marker of proliferation Ki-67 -0.0241525
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.0240942
VPS35L VPS35 endosomal protein sorting factor like -0.0239688
PTRH2 peptidyl-tRNA hydrolase 2 -0.0238535
TNRC18 trinucleotide repeat containing 18 -0.0237942
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0237856
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0237619
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0237171
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.0236836
MAPK8 mitogen-activated protein kinase 8 -0.0236769
DNAAF9 dynein axonemal assembly factor 9 -0.0236698
RPN2 ribophorin II -0.0236474
MAP4 microtubule-associated protein 4 -0.0235837
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 -0.0234995
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.0234664
SETX senataxin -0.0233486
LRPPRC leucine-rich pentatricopeptide repeat containing -0.023335
NF1 neurofibromin 1 -0.02329
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.0231542
PSD3 pleckstrin and Sec7 domain containing 3 -0.0231158
SLC38A1 solute carrier family 38, member 1 -0.0230887
SFTPA2 surfactant protein A2 -0.0230759
SYAP1 synapse associated protein 1 -0.0229809
SDCCAG8 serologically defined colon cancer antigen 8 -0.0228995
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -0.0228689
PLD5 phospholipase D family, member 5 -0.0228094
AXL AXL receptor tyrosine kinase -0.0228075
SVIL supervillin -0.0227901
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0227892
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0227071
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0226933
ADAM10 ADAM metallopeptidase domain 10 -0.0226732
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.0226449
KCNT2 potassium channel, sodium activated subfamily T, member 2 -0.0225993
SQSTM1 sequestosome 1 -0.0224562
PSEN1 presenilin 1 -0.022426
SUGP2 SURP and G patch domain containing 2 -0.0223153
ZNF292 zinc finger protein 292 -0.0222254
PLCB4 phospholipase C, beta 4 -0.0221985
ERBIN erbb2 interacting protein -0.0221845
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0221686
PAIP2 poly(A) binding protein interacting protein 2 -0.022168
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.0221395
TPM1 tropomyosin 1 (alpha) -0.0221384
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.02203
AHI1 Abelson helper integration site 1 -0.0220161
ANKRD26 ankyrin repeat domain 26 -0.0219818
MBTD1 mbt domain containing 1 -0.0219598
NEBL nebulette -0.0219333
VASP vasodilator-stimulated phosphoprotein -0.021895
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0218858
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0218336
ZMYM2 zinc finger, MYM-type 2 -0.0218175
RC3H2 ring finger and CCCH-type domains 2 -0.0217883
PTPRG protein tyrosine phosphatase, receptor type, G -0.02173
PPP6R2 protein phosphatase 6, regulatory subunit 2 -0.0217229
SHLD2 shieldin complex subunit 2 -0.0216815
ARMH3 armadillo like helical domain containing 3 -0.0216452
FADS2 fatty acid desaturase 2 -0.0215979
UBE3C ubiquitin protein ligase E3C -0.0215789
MPHOSPH9 M-phase phosphoprotein 9 -0.0215261
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -0.0212311
GIGYF2 GRB10 interacting GYF protein 2 -0.0212076
ZNF532 zinc finger protein 532 -0.0210882
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0210762
SLC16A4 solute carrier family 16, member 4 -0.0209821
ITGB5 integrin, beta 5 -0.0209612
SEC11A SEC11 homolog A (S. cerevisiae) -0.0209015
ETNK1 ethanolamine kinase 1 -0.0208161
ABI1 abl-interactor 1 -0.0207557
METTL16 methyltransferase like 16 -0.0207421
PDE7B phosphodiesterase 7B -0.0207116
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0206902
THRB thyroid hormone receptor, beta -0.0206854
CCDC57 coiled-coil domain containing 57 -0.02068
ATAD2B ATPase family, AAA domain containing 2B -0.0206782
CLDN2 claudin 2 -0.0206733
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -0.0206584
OGA O-GlcNAcase -0.0206492
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.020645
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0205749
FAM13B family with sequence similarity 13, member B -0.0204986
COL4A5 collagen, type IV, alpha 5 -0.0204295
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 -0.0203543
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0203206
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.0202262
ADAM17 ADAM metallopeptidase domain 17 -0.020157
KIF5B kinesin family member 5B -0.0200686
CUX1 cut-like homeobox 1 -0.0200528
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0199582
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.019933
THOC2 THO complex 2 -0.0198996
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -0.0198732
MARF1 meiosis regulator and mRNA stability factor 1 -0.0198507
SYNGR2 synaptogyrin 2 -0.0198483
PALS2 protein associated with LIN7 2, MAGUK p55 family member -0.0198151
KAT6A K(lysine) acetyltransferase 6A -0.0197955
PHF20 PHD finger protein 20 -0.0197809
RPS18 ribosomal protein S18 -0.0197399
PDLIM5 PDZ and LIM domain 5 -0.0197337
CEP95 centrosomal protein 95kDa -0.0197216
IL13RA1 interleukin 13 receptor, alpha 1 -0.0196567
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0196474
LTAP1 lipid transport auxiliary protein 1 -0.0196262
ZNF33A zinc finger protein 33A -0.0195633
OPHN1 oligophrenin 1 -0.0195425
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.019497
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0194642
TPCN1 two pore segment channel 1 -0.0193975
PLCE1 phospholipase C, epsilon 1 -0.019325
NFE2L1 nuclear factor, erythroid 2-like 1 -0.0193089
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0192756
IRS2 insulin receptor substrate 2 -0.019258
TOR1AIP1 torsin A interacting protein 1 -0.0192241
NCKAP5 NCK-associated protein 5 -0.0191856
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -0.0191846
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.019148
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -0.0191052
MRPS34 mitochondrial ribosomal protein S34 -0.0190902
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -0.0190814
DMXL2 Dmx-like 2 -0.0190526
TRAF3 TNF receptor-associated factor 3 -0.0190427
SLF2 SMC5-SMC6 complex localization factor 2 -0.0190102
DDHD1 DDHD domain containing 1 -0.0189943
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -0.0189299
GLS2 glutaminase 2 (liver, mitochondrial) -0.0189199
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.0189078
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0188498
NOSTRIN nitric oxide synthase trafficking -0.0188459
PRSS23 protease, serine, 23 -0.0188329
PLD3 phospholipase D family, member 3 -0.0187807
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -0.0187201
RHEB Ras homolog enriched in brain -0.0187122
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0186687
XRN2 5'-3' exoribonuclease 2 -0.0185964
CFH complement factor H -0.0185322
RPS21 ribosomal protein S21 -0.0184767
LONP2 lon peptidase 2, peroxisomal -0.0184587
IFT88 intraflagellar transport 88 -0.0184307
KMT5B lysine methyltransferase 5B -0.0184229
CLIP4 CAP-GLY domain containing linker protein family, member 4 -0.0183992
ECE1 endothelin converting enzyme 1 -0.0183991
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.018372
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.0183624
YAP1 Yes-associated protein 1 -0.0183456
ARF4 ADP-ribosylation factor 4 -0.0182843
PAQR5 progestin and adipoQ receptor family member V -0.0182781
FGB fibrinogen beta chain -0.0182653
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -0.0182615
CDC27 cell division cycle 27 -0.0181896
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -0.01815
TMEM120B transmembrane protein 120B -0.0181376
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -0.0180402
RPS3 ribosomal protein S3 -0.0179746
RNF149 ring finger protein 149 -0.0179697
RB1CC1 RB1-inducible coiled-coil 1 -0.0179526
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0179501
RSU1 Ras suppressor protein 1 -0.0179314
MARCHF6 membrane associated ring-CH-type finger 6 -0.0179152
AOPEP aminopeptidase O (putative) -0.0179015
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -0.0178884
S100A6 S100 calcium binding protein A6 -0.0178531
USP53 ubiquitin specific peptidase 53 -0.0178416
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0178097
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.017807
RBPMS RNA binding protein with multiple splicing -0.0177727
VDAC2 voltage-dependent anion channel 2 -0.0177458
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.0177158
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0177051
WDR27 WD repeat domain 27 -0.0176959
G2E3 G2/M-phase specific E3 ubiquitin protein ligase -0.0176422
MINDY3 MINDY lysine 48 deubiquitinase 3 -0.0176415
CTSL cathepsin L -0.0176234
NRP2 neuropilin 2 -0.0176056
UBQLN1 ubiquilin 1 -0.0176047
PRKCSH protein kinase C substrate 80K-H -0.0176035
THRAP3 thyroid hormone receptor associated protein 3 -0.0175875
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.0175721
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0175635
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -0.0175485
PARD3B par-3 family cell polarity regulator beta -0.0174866
TALDO1 transaldolase 1 -0.0174513
ACTG1 actin gamma 1 -0.0174328
CAPN2 calpain 2, (m/II) large subunit -0.0174284
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0174229
CEP89 centrosomal protein 89kDa -0.0174121
SGMS1 sphingomyelin synthase 1 -0.0173886
RASEF RAS and EF-hand domain containing -0.0173845
BABAM2 BRISC and BRCA1 A complex member 2 -0.0173815
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -0.0173722
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0173623
SRSF10 serine/arginine-rich splicing factor 10 -0.0172792
BMERB1 bMERB domain containing 1 -0.0172669
RPL3 ribosomal protein L3 -0.0172601
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0172581
EML2 echinoderm microtubule associated protein like 2 -0.0172526
RIOK3 RIO kinase 3 -0.0172515
WWC2 WW and C2 domain containing 2 -0.0172184
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0172169
VRK2 vaccinia related kinase 2 -0.0172084
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0171625
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0171457
POLE polymerase (DNA directed), epsilon, catalytic subunit -0.0171243
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0171015
NUCB2 nucleobindin 2 -0.0170897
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0170386
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0169732
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -0.016968
KMT2E lysine (K)-specific methyltransferase 2E -0.0169537
WAC WW domain containing adaptor with coiled-coil -0.0169464
MYO5A myosin VA (heavy chain 12, myoxin) -0.016932
LSM12 LSM12 homolog (S. cerevisiae) -0.0169254
VCAN versican -0.0169205
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0169197
PRELID2 PRELI domain containing 2 -0.0169114
GPRIN3 GPRIN family member 3 -0.0169017
GIPC1 GIPC PDZ domain containing family, member 1 -0.016886
IGFBP3 insulin-like growth factor binding protein 3 -0.0168824
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0168495
IP6K2 inositol hexakisphosphate kinase 2 -0.0168208
GRN granulin -0.0168179
EPN2 epsin 2 -0.0168135
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0167977
C2CD5 C2 calcium-dependent domain containing 5 -0.0167953
C1QBP complement component 1, q subcomponent binding protein -0.0167147
AQR aquarius intron-binding spliceosomal factor -0.0167022
SNX8 sorting nexin 8 -0.0166947
FOSL1 FOS-like antigen 1 -0.0166749
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.0166564
UBAP1 ubiquitin associated protein 1 -0.0166407
TXLNG taxilin gamma -0.0166355
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -0.0166118
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.0165987
SEC13 SEC13 homolog (S. cerevisiae) -0.0165895
DCTN2 dynactin 2 (p50) -0.01657
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0165519
FTL ferritin, light polypeptide -0.0165122
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0164917
TSG101 tumor susceptibility 101 -0.0164626
SCO1 SCO1 cytochrome c oxidase assembly protein -0.0164598
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0163954
TM4SF20 transmembrane 4 L six family member 20 -0.0163932
OSBPL3 oxysterol binding protein-like 3 -0.0163909
BCLAF3 BCLAF1 and THRAP3 family member 3 -0.0163771
RHOF ras homolog family member F (in filopodia) -0.0163306
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -0.0163076
ATOSA atos homolog A -0.0162876
CNTLN centlein, centrosomal protein -0.0162796
RAD9A RAD9 homolog A (S. pombe) -0.016265
MECP2 methyl CpG binding protein 2 -0.0162589
TOGARAM1 TOG array regulator of axonemal microtubules 1 -0.0162189
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -0.0162178
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0161995
NR5A2 nuclear receptor subfamily 5, group A, member 2 -0.0161903
RPL7L1 ribosomal protein L7-like 1 -0.0161708
MDM4 MDM4, p53 regulator -0.016156
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.0161421
SMAD6 SMAD family member 6 -0.0161405
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -0.016139
DAD1 defender against cell death 1 -0.0161334
MGA MGA, MAX dimerization protein -0.0161235
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0160934
SCAMP1 secretory carrier membrane protein 1 -0.0160859
ORC3 origin recognition complex, subunit 3 -0.0160779
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0160704
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0160442
GPHN gephyrin -0.0160391
TCF25 transcription factor 25 (basic helix-loop-helix) -0.0160363
MVP major vault protein -0.016035
ZNF33B zinc finger protein 33B -0.0159798
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0159669
LUC7L LUC7-like (S. cerevisiae) -0.0159307
HAGH hydroxyacylglutathione hydrolase -0.0158994
FGG fibrinogen gamma chain -0.0158968
RANBP17 RAN binding protein 17 -0.0158961
SNX14 sorting nexin 14 -0.0158904
GSPT1 G1 to S phase transition 1 -0.0158452
TPT1 tumor protein, translationally-controlled 1 -0.0158229
ZNF331 zinc finger protein 331 -0.0158075
NFU1 NFU1 iron-sulfur cluster scaffold -0.0158016
NFIB nuclear factor I/B -0.0157915
LRMDA leucine rich melanocyte differentiation associated -0.0157866
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0157837
DAND5 DAN domain family member 5, BMP antagonist -0.0157794
SLC38A10 solute carrier family 38, member 10 -0.0157548
TM9SF3 transmembrane 9 superfamily member 3 -0.0157228
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.0156988
HSPA4 heat shock 70kDa protein 4 -0.0156955
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0156633
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.0156466
HEATR6 HEAT repeat containing 6 -0.0156466
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.0156406
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0156288
WDR43 WD repeat domain 43 -0.0156162
BAX BCL2-associated X protein -0.0155829
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0155794
TTC19 tetratricopeptide repeat domain 19 -0.0155483
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0155458
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.015523
CYTH3 cytohesin 3 -0.0155183
HEATR5A HEAT repeat containing 5A -0.0154991
FGFR1 fibroblast growth factor receptor 1 -0.0154948
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 -0.0154384
LTBP1 latent transforming growth factor beta binding protein 1 -0.0154353
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -0.0153763
MAP2K4 mitogen-activated protein kinase kinase 4 -0.0153689
PPP1R9A protein phosphatase 1, regulatory subunit 9A -0.0153518
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0153405
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.0153143
PGM2L1 phosphoglucomutase 2-like 1 -0.0153083
POGZ pogo transposable element with ZNF domain -0.015289
SKIL SKI-like proto-oncogene -0.0152881
ARHGAP12 Rho GTPase activating protein 12 -0.0152812
LETMD1 LETM1 domain containing 1 -0.0152807
TMEM87A transmembrane protein 87A -0.0152728
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.0152579
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -0.0152161
EIF3K eukaryotic translation initiation factor 3, subunit K -0.0152017
RBM26 RNA binding motif protein 26 -0.015193
MEGF8 multiple EGF-like-domains 8 -0.0151587
TTC17 tetratricopeptide repeat domain 17 -0.0151428
RSPO3 R-spondin 3 -0.0151354
BRWD1 bromodomain and WD repeat domain containing 1 -0.0151258
AAGAB alpha- and gamma-adaptin binding protein -0.0151234
SLC39A9 solute carrier family 39, member 9 -0.0151131
PTER phosphotriesterase related -0.0151014
PUDP pseudouridine 5'-phosphatase -0.0151004
GTF2IRD2B GTF2I repeat domain containing 2B -0.0150776
SPPL2A signal peptide peptidase like 2A -0.0150733
MAPK6 mitogen-activated protein kinase 6 -0.0150527