A549_Valproic acid sodium salt_10nM_24h Gene Set

Dataset Sci-Plex Drug Perturbation Signatures
Category transcriptomics
Type drug perturbation
Description Valproic acid sodium salt 10nM perturbation in A549 cell line at 24h timepoint (Sci-Plex)
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Genes

1000 genes differentially expressed following the A549_Valproic acid sodium salt_10nM_24h drug perturbation from the Sci-Plex Drug Perturbation Signatures dataset.

increased expression

Symbol Name Standardized Value
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0853505
SMYD3 SET and MYND domain containing 3 0.0840609
PDE4B phosphodiesterase 4B, cAMP-specific 0.083199
IGF1R insulin-like growth factor 1 receptor 0.0788515
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0723428
PDE4D phosphodiesterase 4D, cAMP-specific 0.0678075
WWOX WW domain containing oxidoreductase 0.0595002
TBC1D5 TBC1 domain family, member 5 0.0594781
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0586577
NRCAM neuronal cell adhesion molecule 0.0582244
KRT18 keratin 18, type I 0.0571383
DST dystonin 0.056231
MYO10 myosin X 0.0543179
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0541606
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0534218
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0519961
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0514219
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.0511586
CENPF centromere protein F, 350/400kDa 0.0493663
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.0490963
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0486281
DGKG diacylglycerol kinase, gamma 90kDa 0.0484673
AKR1C2 aldo-keto reductase family 1, member C2 0.0480492
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0471543
RAB10 RAB10, member RAS oncogene family 0.0470427
PKM pyruvate kinase, muscle 0.0461566
SETD2 SET domain containing 2 0.0460258
PHGDH phosphoglycerate dehydrogenase 0.0456875
S100A10 S100 calcium binding protein A10 0.0446794
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.044148
CDK6 cyclin-dependent kinase 6 0.0440765
ZFHX3 zinc finger homeobox 3 0.0439115
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.043552
DTNB dystrobrevin, beta 0.0434375
PBX1 pre-B-cell leukemia homeobox 1 0.0428738
TNS3 tensin 3 0.0426331
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.040793
NAMPT nicotinamide phosphoribosyltransferase 0.0407837
SBF2 SET binding factor 2 0.0395757
GLIS3 GLIS family zinc finger 3 0.0393113
UGDH UDP-glucose 6-dehydrogenase 0.0391771
PDE7B phosphodiesterase 7B 0.0384187
TFF1 trefoil factor 1 0.0383623
SEPTIN9 septin 9 0.0376678
TMCC1 transmembrane and coiled-coil domain family 1 0.0370617
GOLGA4 golgin A4 0.0369933
ARHGAP35 Rho GTPase activating protein 35 0.0369834
SIL1 SIL1 nucleotide exchange factor 0.0369017
UBTF upstream binding transcription factor, RNA polymerase I 0.0368924
ARL4C ADP-ribosylation factor-like 4C 0.0368224
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0365907
MAP7 microtubule-associated protein 7 0.0365598
CLASP1 cytoplasmic linker associated protein 1 0.0364089
TUBA1B tubulin, alpha 1b 0.0360329
NEBL nebulette 0.0347267
BCL2L1 BCL2-like 1 0.0345826
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.0344368
SLC38A1 solute carrier family 38, member 1 0.0343902
MAP4 microtubule-associated protein 4 0.0342921
MKI67 marker of proliferation Ki-67 0.0341321
CENPP centromere protein P 0.0341138
RPLP1 ribosomal protein, large, P1 0.0340301
SPIDR scaffolding protein involved in DNA repair 0.0336544
CDCA2 cell division cycle associated 2 0.0334488
AFG2A AFG2 AAA ATPase homolog A 0.033445
AHNAK2 AHNAK nucleoprotein 2 0.0332216
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0331832
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.0330816
PHACTR4 phosphatase and actin regulator 4 0.0330081
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0326536
SIK3 SIK family kinase 3 0.0326176
MFF mitochondrial fission factor 0.0325196
BICC1 BicC family RNA binding protein 1 0.0317935
ZNF217 zinc finger protein 217 0.0317516
PSPC1 paraspeckle component 1 0.0313584
RAD18 RAD18 E3 ubiquitin protein ligase 0.0312148
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0311541
RABGAP1 RAB GTPase activating protein 1 0.0310335
KIF14 kinesin family member 14 0.0310075
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.030998
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.0309302
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0308963
FGFR1 fibroblast growth factor receptor 1 0.0308483
SBNO1 strawberry notch homolog 1 (Drosophila) 0.0304624
NBAS neuroblastoma amplified sequence 0.0303034
NOP58 NOP58 ribonucleoprotein 0.030014
HMOX1 heme oxygenase 1 0.029848
PIAS1 protein inhibitor of activated STAT, 1 0.0296855
ANKLE2 ankyrin repeat and LEM domain containing 2 0.0294726
STK24 serine/threonine kinase 24 0.0294564
HP1BP3 heterochromatin protein 1, binding protein 3 0.0292333
PCNX2 pecanex 2 0.0291378
MIS18BP1 MIS18 binding protein 1 0.0290079
HDAC4 histone deacetylase 4 0.0288717
MACROD1 MACRO domain containing 1 0.0285668
DENND1A DENN/MADD domain containing 1A 0.0285467
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0285076
NLK nemo-like kinase 0.0283774
GCLM glutamate-cysteine ligase, modifier subunit 0.0282058
FTO fat mass and obesity associated 0.0281155
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.0279346
BLM Bloom syndrome, RecQ helicase-like 0.0277858
NONO non-POU domain containing, octamer-binding 0.0277703
DCP2 decapping mRNA 2 0.0275775
WDPCP WD repeat containing planar cell polarity effector 0.0274209
TBCE tubulin folding cofactor E 0.0273308
SFTPA2 surfactant protein A2 0.0272377
PON2 paraoxonase 2 0.02722
HEATR6 HEAT repeat containing 6 0.0271956
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.0271715
SOCS5 suppressor of cytokine signaling 5 0.0271362
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.027061
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0269756
FAM168A family with sequence similarity 168, member A 0.0266534
NCKAP1 NCK-associated protein 1 0.0266448
ANXA2 annexin A2 0.0265825
REEP5 receptor accessory protein 5 0.0265075
MMS22L MMS22-like, DNA repair protein 0.0264986
MPG N-methylpurine-DNA glycosylase 0.0264675
SRBD1 S1 RNA binding domain 1 0.0263239
PRPF4B pre-mRNA processing factor 4B 0.0262882
CTCF CCCTC-binding factor (zinc finger protein) 0.0262742
MYOF myoferlin 0.0262549
LITAF lipopolysaccharide-induced TNF factor 0.0262224
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0261094
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.0260908
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.0260584
RPS8 ribosomal protein S8 0.0260225
NXN nucleoredoxin 0.0258913
ZC3H18 zinc finger CCCH-type containing 18 0.0258107
PDE10A phosphodiesterase 10A 0.0257694
BMP6 bone morphogenetic protein 6 0.0257685
PTPRM protein tyrosine phosphatase, receptor type, M 0.0256976
CUEDC1 CUE domain containing 1 0.0256416
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.0255441
IMMT inner membrane protein, mitochondrial 0.0255278
ARL15 ADP-ribosylation factor-like 15 0.025458
PARG poly (ADP-ribose) glycohydrolase 0.0254156
RSPO3 R-spondin 3 0.0253573
GRB2 growth factor receptor-bound protein 2 0.0252608
GPHN gephyrin 0.0252171
DIAPH1 diaphanous-related formin 1 0.0252058
PUM1 pumilio RNA-binding family member 1 0.0250471
EVL Enah/Vasp-like 0.0249766
RAD51B RAD51 paralog B 0.0249646
SENP5 SUMO1/sentrin specific peptidase 5 0.0249094
RBM47 RNA binding motif protein 47 0.0248329
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.0247418
EGFR epidermal growth factor receptor 0.0247389
CTSD cathepsin D 0.0246615
CEP128 centrosomal protein 128kDa 0.0246511
CPLX2 complexin 2 0.0246426
CNKSR3 CNKSR family member 3 0.0246364
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.0246118
TXN2 thioredoxin 2 0.024464
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0244344
UBE2O ubiquitin-conjugating enzyme E2O 0.0244252
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0244088
DOCK7 dedicator of cytokinesis 7 0.0243833
NSD1 nuclear receptor binding SET domain protein 1 0.0243773
TUFM Tu translation elongation factor, mitochondrial 0.0243044
CEP350 centrosomal protein 350kDa 0.0242024
DDB2 damage-specific DNA binding protein 2, 48kDa 0.0238192
CEP112 centrosomal protein 112kDa 0.0236869
AGFG1 ArfGAP with FG repeats 1 0.0235825
CPT1A carnitine palmitoyltransferase 1A (liver) 0.0235726
KATNIP katanin interacting protein 0.023483
CCNJL cyclin J-like 0.0234467
MYBBP1A MYB binding protein (P160) 1a 0.0234262
GRAMD1A GRAM domain containing 1A 0.0234222
COASY CoA synthase 0.0234154
YAP1 Yes-associated protein 1 0.0233757
PHF20 PHD finger protein 20 0.0233754
NUP153 nucleoporin 153kDa 0.0233511
ANKRD17 ankyrin repeat domain 17 0.0233266
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0232962
ETV6 ets variant 6 0.0232725
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.0230793
ZNF789 zinc finger protein 789 0.023067
KANK1 KN motif and ankyrin repeat domains 1 0.0230318
CREB1 cAMP responsive element binding protein 1 0.0230229
NPAS2 neuronal PAS domain protein 2 0.0229698
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0229529
LUZP1 leucine zipper protein 1 0.0228292
NCAPG2 non-SMC condensin II complex, subunit G2 0.0228094
SRPK2 SRSF protein kinase 2 0.0227746
RPL12 ribosomal protein L12 0.0227725
ANXA1 annexin A1 0.0227658
SLIT3 slit homolog 3 (Drosophila) 0.0226618
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.0226309
AHI1 Abelson helper integration site 1 0.0226078
PKP4 plakophilin 4 0.0225433
GPX2 glutathione peroxidase 2 0.0224762
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0224295
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0223632
ODF2 outer dense fiber of sperm tails 2 0.0223388
CENPI centromere protein I 0.0221967
SPNS1 spinster homolog 1 (Drosophila) 0.0221889
TCF12 transcription factor 12 0.0221644
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.022139
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0220854
PUM3 pumilio RNA binding family member 3 0.0220714
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.0220394
MARK2 MAP/microtubule affinity-regulating kinase 2 0.0220259
COPA coatomer protein complex, subunit alpha 0.0220088
PKN2 protein kinase N2 0.0218971
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0218212
ITPRID2 ITPR interacting domain containing 2 0.0218047
TRAP1 TNF receptor-associated protein 1 0.021745
MYO19 myosin XIX 0.0216956
MACF1 microtubule-actin crosslinking factor 1 0.0216497
GSTCD glutathione S-transferase, C-terminal domain containing 0.0216353
KIF2A kinesin heavy chain member 2A 0.0216294
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.0215896
NUP62 nucleoporin 62kDa 0.021519
DENR density-regulated protein 0.0214948
PTK2 protein tyrosine kinase 2 0.0214563
RPL30 ribosomal protein L30 0.0214513
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.0212881
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.0212368
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.0212109
HJURP Holliday junction recognition protein 0.0211483
COX5B cytochrome c oxidase subunit Vb 0.0210648
SLC45A4 solute carrier family 45, member 4 0.0210323
ZFYVE16 zinc finger, FYVE domain containing 16 0.0210044
EIF1 eukaryotic translation initiation factor 1 0.0208432
LDHA lactate dehydrogenase A 0.0208157
RBMX RNA binding motif protein, X-linked 0.0207613
NBEAL1 neurobeachin-like 1 0.0207544
TMEM131 transmembrane protein 131 0.0207226
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0207187
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.0206896
TRIM56 tripartite motif containing 56 0.0206356
MYSM1 Myb-like, SWIRM and MPN domains 1 0.0205988
SMAD3 SMAD family member 3 0.0204999
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0204943
PHF14 PHD finger protein 14 0.0204692
NRIP1 nuclear receptor interacting protein 1 0.0204648
DNM2 dynamin 2 0.0204437
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.0203526
CNST consortin, connexin sorting protein 0.0203368
NEO1 neogenin 1 0.0203076
TPM3 tropomyosin 3 0.0202986
FLNB filamin B, beta 0.0202402
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.0202271
RPL37A ribosomal protein L37a 0.020221
BTBD1 BTB (POZ) domain containing 1 0.0202196
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0201747
ZBTB7A zinc finger and BTB domain containing 7A 0.0201306
MAPK1 mitogen-activated protein kinase 1 0.020123
STXBP4 syntaxin binding protein 4 0.0200915
KYAT1 kynurenine aminotransferase 1 0.0200757
GPC6 glypican 6 0.0200652
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0200512
EDN1 endothelin 1 0.0200491
GSK3B glycogen synthase kinase 3 beta 0.0200261
CENPE centromere protein E, 312kDa 0.0200203
ANKRD26 ankyrin repeat domain 26 0.0199908
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.0198857
TACC2 transforming, acidic coiled-coil containing protein 2 0.0198856
PRDX5 peroxiredoxin 5 0.019867
SERBP1 SERPINE1 mRNA binding protein 1 0.0198324
KLHDC10 kelch domain containing 10 0.0197554
NUP160 nucleoporin 160kDa 0.0197522
HSPH1 heat shock 105kDa/110kDa protein 1 0.0197332
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0197151
ARHGAP21 Rho GTPase activating protein 21 0.0197079
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.019591
ARRB1 arrestin, beta 1 0.0195746
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.0195504
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0195108
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.0194658
DESI2 desumoylating isopeptidase 2 0.0194418
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 0.0194244
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.0194073
CCDC88A coiled-coil domain containing 88A 0.0192421
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 0.0192337
NSRP1 nuclear speckle splicing regulatory protein 1 0.0191838
RPS28 ribosomal protein S28 0.019183
KRT8 keratin 8, type II 0.0191462
RAB31 RAB31, member RAS oncogene family 0.0191394
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0191051
SREBF2 sterol regulatory element binding transcription factor 2 0.0190142
SGMS1 sphingomyelin synthase 1 0.0189457
FRYL FRY-like 0.0189407
SLC39A11 solute carrier family 39, member 11 0.0189078
H4C3 H4 clustered histone 3 0.0188632
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0187951
R3HDM1 R3H domain containing 1 0.0187385
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0187269
BRI3BP BRI3 binding protein 0.0187217
PITPNA phosphatidylinositol transfer protein, alpha 0.0187111
ECT2 epithelial cell transforming 2 0.0187109
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.0187088
APTX aprataxin 0.0186873
GSTP1 glutathione S-transferase pi 1 0.0186815
IER3 immediate early response 3 0.0186793
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.0186148
NKTR natural killer cell triggering receptor 0.0185989
EPN2 epsin 2 0.0185925
USP49 ubiquitin specific peptidase 49 0.0185856
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.0185557
EIF4A1 eukaryotic translation initiation factor 4A1 0.0185459
CCND3 cyclin D3 0.0184686
PUS7 pseudouridylate synthase 7 (putative) 0.0184591
NRP2 neuropilin 2 0.0183407
MAST2 microtubule associated serine/threonine kinase 2 0.0183192
ZNF277 zinc finger protein 277 0.0182941
AEBP2 AE binding protein 2 0.0182675
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.0182639
HSPB1 heat shock 27kDa protein 1 0.0182519
MYO5A myosin VA (heavy chain 12, myoxin) 0.0182391
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0182239
BLTP3B bridge-like lipid transfer protein family member 3B 0.0182173
AZIN1 antizyme inhibitor 1 0.0182151
IER5L immediate early response 5-like 0.0182088
LIMCH1 LIM and calponin homology domains 1 0.0181648
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.0181527
STIP1 stress-induced phosphoprotein 1 0.0181138
NR2C1 nuclear receptor subfamily 2, group C, member 1 0.0181048
OPN3 opsin 3 0.018104
ZNF106 zinc finger protein 106 0.0180796
BLTP2 bridge-like lipid transfer protein family member 2 0.0180696
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.0180418
ATG7 autophagy related 7 0.018009
SREBF1 sterol regulatory element binding transcription factor 1 0.0180039
CARS1 cysteinyl-tRNA synthetase 1 0.0179472
ESYT2 extended synaptotagmin-like protein 2 0.0179357
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0179126
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.0178906
FBXL20 F-box and leucine-rich repeat protein 20 0.0178003
HMOX2 heme oxygenase 2 0.0177876
CEP152 centrosomal protein 152kDa 0.0177849
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.0177362
KLHL5 kelch-like family member 5 0.0176814
TMED9 transmembrane emp24 protein transport domain containing 9 0.0176653
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0176196
NRDC nardilysin convertase 0.0176185
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0175839
KMT2A lysine (K)-specific methyltransferase 2A 0.0175828
RASAL2 RAS protein activator like 2 0.0175815
GTSE1 G-2 and S-phase expressed 1 0.0175735
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.0175513
AURKB aurora kinase B 0.0175418
UBE2N ubiquitin-conjugating enzyme E2N 0.0175388
CKAP2 cytoskeleton associated protein 2 0.0175322
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.0175289
S100A6 S100 calcium binding protein A6 0.0175093
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0175077
NCOA3 nuclear receptor coactivator 3 0.0175046
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0174717
RBMS2 RNA binding motif, single stranded interacting protein 2 0.0174564
TAOK3 TAO kinase 3 0.0174192
MTRFR mitochondrial translation release factor in rescue 0.0174086
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0173881
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0173428
PARVB parvin, beta 0.0173342
EIF3A eukaryotic translation initiation factor 3, subunit A 0.017318
RC3H1 ring finger and CCCH-type domains 1 0.0172718
DDHD1 DDHD domain containing 1 0.0172645
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 0.0172599
CKAP5 cytoskeleton associated protein 5 0.0172588
PEAK1 pseudopodium-enriched atypical kinase 1 0.017243
RPL4 ribosomal protein L4 0.0172408
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0172319
NUP54 nucleoporin 54kDa 0.0172255
DCTN4 dynactin 4 (p62) 0.0172071
JARID2 jumonji, AT rich interactive domain 2 0.0171954
EPDR1 ependymin related 1 0.0171938
RPL23 ribosomal protein L23 0.0171888
ZMYND8 zinc finger, MYND-type containing 8 0.0171124
MYL12B myosin, light chain 12B, regulatory 0.0170611
MEIS2 Meis homeobox 2 0.0170088
RGS20 regulator of G-protein signaling 20 0.0170026
EMP2 epithelial membrane protein 2 0.0168621
EHBP1 EH domain binding protein 1 0.0168609
KCTD3 potassium channel tetramerization domain containing 3 0.0168605
APAF1 apoptotic peptidase activating factor 1 0.0168328
PDPK1 3-phosphoinositide dependent protein kinase 1 0.0168309
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.0168104
PTMS parathymosin 0.0167901
AMBRA1 autophagy/beclin-1 regulator 1 0.016738
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.0167342
DCTN1 dynactin 1 0.0167134
TPX2 TPX2, microtubule-associated 0.0166941
ACADVL acyl-CoA dehydrogenase, very long chain 0.0166934
CLYBL citrate lyase beta like 0.0166772
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 0.0166767
ERP29 endoplasmic reticulum protein 29 0.0166714
ARHGAP32 Rho GTPase activating protein 32 0.0166684
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.0166551
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 0.0166482
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0166444
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.0166369
TGFBI transforming growth factor, beta-induced, 68kDa 0.0166237
RPL34 ribosomal protein L34 0.0166048
SNX4 sorting nexin 4 0.016574
USP47 ubiquitin specific peptidase 47 0.016567
MAP2K1 mitogen-activated protein kinase kinase 1 0.0165653
WDR27 WD repeat domain 27 0.0165464
GPR107 G protein-coupled receptor 107 0.0165307
RECQL4 RecQ protein-like 4 0.0165269
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0164798
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 0.0164779
ZBTB4 zinc finger and BTB domain containing 4 0.0164109
UBE4B ubiquitination factor E4B 0.0164022
MARCHF7 membrane associated ring-CH-type finger 7 0.0163892
COL5A2 collagen, type V, alpha 2 0.0163787
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.0163327
RFC2 replication factor C (activator 1) 2, 40kDa 0.0163087
BAG3 BCL2-associated athanogene 3 0.0163055
MPZL1 myelin protein zero-like 1 0.0162583
D2HGDH D-2-hydroxyglutarate dehydrogenase 0.0161859
NXPE3 neurexophilin and PC-esterase domain family, member 3 0.0161823
AKAP1 A kinase (PRKA) anchor protein 1 0.0161359
BARD1 BRCA1 associated RING domain 1 0.016104
YAF2 YY1 associated factor 2 0.0160618
DHCR7 7-dehydrocholesterol reductase 0.016049
USP37 ubiquitin specific peptidase 37 0.0160414
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.0160384
ENAH enabled homolog (Drosophila) 0.0160238
WWC2 WW and C2 domain containing 2 0.0159939
MIA2 melanoma inhibitory activity 2 0.0159704
COPS6 COP9 signalosome subunit 6 0.0159495
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 0.0159307
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.0159279
SOGA1 suppressor of glucose, autophagy associated 1 0.0159068
EXOC4 exocyst complex component 4 0.0158976
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.0158299
SNRPA small nuclear ribonucleoprotein polypeptide A 0.0158246
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0158049
ATXN2L ataxin 2-like 0.0158003
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.0158002
PDCD11 programmed cell death 11 0.0157924
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0157452
RAD52 RAD52 homolog (S. cerevisiae) 0.0157188
H1-10 H1.10 linker histone 0.0157124
RPL32 ribosomal protein L32 0.0156855
TLE5 TLE family member 5, transcriptional modulator 0.0156836
RTTN rotatin 0.0156636
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0156398
SNX29 sorting nexin 29 0.0156248
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0156163
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.0156068
PTPRF protein tyrosine phosphatase, receptor type, F 0.0155911
ZFP64 ZFP64 zinc finger protein 0.0155907
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0155837
CUX1 cut-like homeobox 1 0.0155728
ITGB4 integrin, beta 4 0.0155483
JADE2 jade family PHD finger 2 0.0155412
TRIM44 tripartite motif containing 44 0.0155251
TGFB1 transforming growth factor, beta 1 0.0155164
DLG1 discs, large homolog 1 (Drosophila) 0.0155118
EBF1 early B-cell factor 1 0.0154704
KAT6A K(lysine) acetyltransferase 6A 0.0154589
ATAD5 ATPase family, AAA domain containing 5 0.0154545
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0154458
RPLP2 ribosomal protein, large, P2 0.0154215
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.0154048
CD46 CD46 molecule, complement regulatory protein 0.0154036
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.015403
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.0153768
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.0153747
ZNF280D zinc finger protein 280D 0.0153713
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0153591
IDI1 isopentenyl-diphosphate delta isomerase 1 0.0153299
TGOLN2 trans-golgi network protein 2 0.0153252
SCLT1 sodium channel and clathrin linker 1 0.0153241
UBE2I ubiquitin-conjugating enzyme E2I 0.0153089
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 0.0152843
SYNE2 spectrin repeat containing, nuclear envelope 2 0.015281
AGO2 argonaute RISC catalytic component 2 0.0152778
DRAM1 DNA-damage regulated autophagy modulator 1 0.0152384
STAMBP STAM binding protein 0.0152137
INO80D INO80 complex subunit D 0.0151837
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0151781
USPL1 ubiquitin specific peptidase like 1 0.0151737
KIF2C kinesin family member 2C 0.0151638
CHD4 chromodomain helicase DNA binding protein 4 0.0151478
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.0151188
KATNAL2 katanin p60 subunit A-like 2 0.0150791
TTLL10 tubulin tyrosine ligase-like family member 10 0.0150484
RDX radixin 0.0150438
GFRA1 GDNF family receptor alpha 1 0.0150371
PACS1 phosphofurin acidic cluster sorting protein 1 0.0150303
CUL2 cullin 2 0.0150296
FRMD5 FERM domain containing 5 0.0150128
GOLT1A golgi transport 1A 0.0150101
TCF20 transcription factor 20 (AR1) 0.0149896
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.0149789
KIDINS220 kinase D-interacting substrate, 220kDa 0.014911
CCNY cyclin Y 0.0149003
ERBIN erbb2 interacting protein 0.0148929
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0148549
MGST1 microsomal glutathione S-transferase 1 0.0148525
TXNDC15 thioredoxin domain containing 15 0.0148513
TCAF1 TRPM8 channel-associated factor 1 0.014834
CD151 CD151 molecule (Raph blood group) 0.0148281
SNX8 sorting nexin 8 0.0147506
TSPAN4 tetraspanin 4 0.0147441

decreased expression

Symbol Name Standardized Value
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.128778
MTUS1 microtubule associated tumor suppressor 1 -0.0955222
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.0899566
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0859315
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 -0.080868
SLTM SAFB-like, transcription modulator -0.073956
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.0738043
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0717563
AGR2 anterior gradient 2 -0.0710774
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0690313
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -0.0615543
CA12 carbonic anhydrase XII -0.061123
ARHGAP26 Rho GTPase activating protein 26 -0.0600476
CNTNAP3B contactin associated protein-like 3B -0.0596784
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0571432
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0557324
USP3 ubiquitin specific peptidase 3 -0.0519952
NRP1 neuropilin 1 -0.0518467
AKR1C1 aldo-keto reductase family 1, member C1 -0.0514588
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0502826
TTC28 tetratricopeptide repeat domain 28 -0.0502232
HDLBP high density lipoprotein binding protein -0.0471204
PCDH9 protocadherin 9 -0.0468917
FCGBP Fc fragment of IgG binding protein -0.0451974
KRT81 keratin 81, type II -0.0450545
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0443351
RNF213 ring finger protein 213 -0.0443107
NRG1 neuregulin 1 -0.0439456
THSD4 thrombospondin, type I, domain containing 4 -0.0437744
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0433248
FN1 fibronectin 1 -0.0431331
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.042634
LMNA lamin A/C -0.0419052
ARHGAP5 Rho GTPase activating protein 5 -0.0414851
SQSTM1 sequestosome 1 -0.0413196
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0409289
PTPRJ protein tyrosine phosphatase, receptor type, J -0.0397752
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0396487
PDE8A phosphodiesterase 8A -0.0390001
THSD7A thrombospondin, type I, domain containing 7A -0.0389868
TPM4 tropomyosin 4 -0.0385923
PDLIM5 PDZ and LIM domain 5 -0.0383178
MCU mitochondrial calcium uniporter -0.0382969
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0382939
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0381784
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0370616
FAM107B family with sequence similarity 107, member B -0.0367306
PDZD8 PDZ domain containing 8 -0.0364475
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0363542
ANXA4 annexin A4 -0.0362624
JUP junction plakoglobin -0.0360509
DIAPH2 diaphanous-related formin 2 -0.0359555
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0354699
PLCB4 phospholipase C, beta 4 -0.0352639
VDAC2 voltage-dependent anion channel 2 -0.0349873
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0346465
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0342255
WASF2 WAS protein family, member 2 -0.0338913
RBM6 RNA binding motif protein 6 -0.0337973
DOCK5 dedicator of cytokinesis 5 -0.0337025
TBL1X transducin (beta)-like 1X-linked -0.0335907
GMDS GDP-mannose 4,6-dehydratase -0.0335868
CP ceruloplasmin (ferroxidase) -0.0334518
ABTB3 ankyrin repeat and BTB domain containing 3 -0.0332335
RAB1A RAB1A, member RAS oncogene family -0.0332115
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0331693
MAML3 mastermind-like 3 (Drosophila) -0.0330075
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0328194
CDC27 cell division cycle 27 -0.0326605
ITGAV integrin, alpha V -0.0325555
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.0324551
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0323046
DSTN destrin (actin depolymerizing factor) -0.0321309
CDK17 cyclin-dependent kinase 17 -0.0318843
KMT2C lysine (K)-specific methyltransferase 2C -0.0316198
FHIT fragile histidine triad -0.0314916
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0312971
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0310882
GNB5 guanine nucleotide binding protein (G protein), beta 5 -0.0310256
HIP1 huntingtin interacting protein 1 -0.0310222
PCYOX1 prenylcysteine oxidase 1 -0.030956
RPL8 ribosomal protein L8 -0.0307952
RAP1B RAP1B, member of RAS oncogene family -0.0303472
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0302551
CEMIP2 cell migration inducing hyaluronidase 2 -0.0301908
RNF43 ring finger protein 43 -0.0300056
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.0297023
LIPH lipase, member H -0.0295818
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0294492
CYSTM1 cysteine-rich transmembrane module containing 1 -0.0292638
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.0291157
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.0288651
LPAR1 lysophosphatidic acid receptor 1 -0.0288554
MYO1B myosin IB -0.028728
TMEM65 transmembrane protein 65 -0.0286548
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0286175
MGLL monoglyceride lipase -0.0286115
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0283923
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.0283872
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.02829
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0281688
ATXN1 ataxin 1 -0.0279587
PDIA4 protein disulfide isomerase family A, member 4 -0.0279331
RPL15 ribosomal protein L15 -0.0278563
PDS5A PDS5 cohesin associated factor A -0.0278055
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0277591
SERINC5 serine incorporator 5 -0.0276183
KATNBL1 katanin p80 subunit B-like 1 -0.0276129
R3HDM2 R3H domain containing 2 -0.0273623
ENSA endosulfine alpha -0.027353
XRN1 5'-3' exoribonuclease 1 -0.0272471
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -0.0271666
TNRC6A trinucleotide repeat containing 6A -0.0269779
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0269424
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0269387
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0267517
PTPRA protein tyrosine phosphatase, receptor type, A -0.0267479
REEP3 receptor accessory protein 3 -0.0264382
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0263981
DNM1 dynamin 1 -0.0262036
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.0261617
AVPI1 arginine vasopressin-induced 1 -0.0260217
FRS2 fibroblast growth factor receptor substrate 2 -0.0259721
KLF3 Kruppel-like factor 3 (basic) -0.0258837
VSIG10 V-set and immunoglobulin domain containing 10 -0.0257887
CTBP2 C-terminal binding protein 2 -0.0257732
CNTN1 contactin 1 -0.0257517
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0256996
VCAN versican -0.0256727
CNTNAP3 contactin associated protein-like 3 -0.0256548
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0255989
ACBD3 acyl-CoA binding domain containing 3 -0.0255541
CST3 cystatin C -0.0255079
ZNF638 zinc finger protein 638 -0.0254787
SCAF11 SR-related CTD-associated factor 11 -0.0252967
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0252285
NOSTRIN nitric oxide synthase trafficking -0.0250926
AOPEP aminopeptidase O (putative) -0.025073
MRPS35 mitochondrial ribosomal protein S35 -0.0249794
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.0249622
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.0247074
SH3KBP1 SH3-domain kinase binding protein 1 -0.0245525
YIPF4 Yip1 domain family, member 4 -0.024535
ZNRF3 zinc and ring finger 3 -0.0244985
MYLK myosin light chain kinase -0.0241465
ANTXR1 anthrax toxin receptor 1 -0.0241304
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0241222
CALD1 caldesmon 1 -0.0241138
NFX1 nuclear transcription factor, X-box binding 1 -0.0241084
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.0239991
TMEM245 transmembrane protein 245 -0.0239939
CLSTN1 calsyntenin 1 -0.0239474
ANKRD30A ankyrin repeat domain 30A -0.0239399
PHC3 polyhomeotic homolog 3 (Drosophila) -0.0239175
ATXN2 ataxin 2 -0.0237467
TNPO1 transportin 1 -0.023743
ANAPC16 anaphase promoting complex subunit 16 -0.0236555
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0236255
PPA2 pyrophosphatase (inorganic) 2 -0.0235857
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0233768
YBX3 Y box binding protein 3 -0.0232824
KYNU kynureninase -0.0232609
FOSL1 FOS-like antigen 1 -0.0232513
ZFP36L2 ZFP36 ring finger protein-like 2 -0.0232496
LPP LIM domain containing preferred translocation partner in lipoma -0.0232239
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.023196
PRPF3 pre-mRNA processing factor 3 -0.0231796
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0231336
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0231309
EXT1 exostosin glycosyltransferase 1 -0.0230908
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0230342
PHF21A PHD finger protein 21A -0.0228488
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.0227797
TMEM44 transmembrane protein 44 -0.0227367
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0227283
RETREG3 reticulophagy regulator family member 3 -0.0226667
ZMYM2 zinc finger, MYM-type 2 -0.0226084
CGGBP1 CGG triplet repeat binding protein 1 -0.0225684
ERGIC3 ERGIC and golgi 3 -0.0224581
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -0.0224325
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0224281
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.0224206
RNF130 ring finger protein 130 -0.0224181
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0223938
PTPRK protein tyrosine phosphatase, receptor type, K -0.0223393
SYT17 synaptotagmin XVII -0.0222586
RPL7L1 ribosomal protein L7-like 1 -0.0221724
CTTN cortactin -0.0221664
GPATCH2L G patch domain containing 2-like -0.0221572
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.0221055
LUC7L LUC7-like (S. cerevisiae) -0.0220494
CD109 CD109 molecule -0.0220395
ZNF33B zinc finger protein 33B -0.0219981
GABPB2 GA binding protein transcription factor, beta subunit 2 -0.0218776
SHLD1 shieldin complex subunit 1 -0.0218443
DENND4A DENN/MADD domain containing 4A -0.0218328
TTF1 transcription termination factor, RNA polymerase I -0.0218125
PCED1B PC-esterase domain containing 1B -0.0217037
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0215854
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 -0.0215515
SEC16A SEC16 homolog A (S. cerevisiae) -0.0214793
CORO2A coronin, actin binding protein, 2A -0.0214634
USP8 ubiquitin specific peptidase 8 -0.0214537
MAPK6 mitogen-activated protein kinase 6 -0.0214515
ZZZ3 zinc finger, ZZ-type containing 3 -0.0214167
LRP10 low density lipoprotein receptor-related protein 10 -0.0213426
CHD9 chromodomain helicase DNA binding protein 9 -0.0213394
TPM2 tropomyosin 2 (beta) -0.0213155
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -0.0212775
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0212596
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0212481
PLD3 phospholipase D family, member 3 -0.0212345
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0212169
TP53 tumor protein p53 -0.0212137
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -0.0211518
SECISBP2L SECIS binding protein 2-like -0.0211481
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.021147
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.0211256
MISP mitotic spindle positioning -0.0210841
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.021059
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0210195
MFSD6 major facilitator superfamily domain containing 6 -0.0210081
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.0210013
GCLC glutamate-cysteine ligase, catalytic subunit -0.0209858
RBL2 retinoblastoma-like 2 -0.020935
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -0.02093
UNK unkempt family zinc finger -0.0207761
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.0207294
IQCB1 IQ motif containing B1 -0.0207061
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.020629
SSH2 slingshot protein phosphatase 2 -0.020417
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.0204
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0203848
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.020345
DOCK10 dedicator of cytokinesis 10 -0.0202988
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0202934
PLS3 plastin 3 -0.0202205
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.020175
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0201553
CANX calnexin -0.0201314
FNBP4 formin binding protein 4 -0.0201257
SMAD2 SMAD family member 2 -0.0201033
KAT6B K(lysine) acetyltransferase 6B -0.0200646
TUBD1 tubulin, delta 1 -0.0197833
FNDC3A fibronectin type III domain containing 3A -0.0197812
JMJD1C jumonji domain containing 1C -0.0197751
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.0197075
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0196925
XPO1 exportin 1 -0.0196346
BABAM2 BRISC and BRCA1 A complex member 2 -0.0195324
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.0194772
RBM39 RNA binding motif protein 39 -0.0194612
EML4 echinoderm microtubule associated protein like 4 -0.0194442
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -0.0194134
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.019392
FOXP1 forkhead box P1 -0.0193767
PRPF6 pre-mRNA processing factor 6 -0.0193364
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.0193328
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.0192246
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0192202
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0192089
RAB6A RAB6A, member RAS oncogene family -0.0191843
ZMIZ1 zinc finger, MIZ-type containing 1 -0.0191524
RNF145 ring finger protein 145 -0.0191252
SKIL SKI-like proto-oncogene -0.0191216
CSNK2A2 casein kinase 2, alpha prime polypeptide -0.0190951
POTEF POTE ankyrin domain family, member F -0.0189146
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -0.0188911
ACTN1 actinin, alpha 1 -0.0188663
AHCYL1 adenosylhomocysteinase-like 1 -0.0188449
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.0188047
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0187062
TXNRD1 thioredoxin reductase 1 -0.0186911
L2HGDH L-2-hydroxyglutarate dehydrogenase -0.0186449
STRN3 striatin, calmodulin binding protein 3 -0.0186209
STK32B serine/threonine kinase 32B -0.0186088
MANBA mannosidase, beta A, lysosomal -0.0185893
ADNP2 ADNP homeobox 2 -0.0185695
ADD3 adducin 3 (gamma) -0.0185681
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0185226
PRKCA protein kinase C, alpha -0.0184896
CDK13 cyclin-dependent kinase 13 -0.0184276
KSR1 kinase suppressor of ras 1 -0.0184241
OSBPL3 oxysterol binding protein-like 3 -0.0184059
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -0.0183906
STRBP spermatid perinuclear RNA binding protein -0.0183282
SESTD1 SEC14 and spectrin domains 1 -0.0183058
GCFC2 GC-rich sequence DNA-binding factor 2 -0.0182975
NTN4 netrin 4 -0.0182909
WIPF1 WAS/WASL interacting protein family, member 1 -0.0182881
ZBTB20 zinc finger and BTB domain containing 20 -0.0182498
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.018239
CLOCK clock circadian regulator -0.0182371
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.0181977
FOCAD focadhesin -0.0181873
HEATR5B HEAT repeat containing 5B -0.0181562
N4BP2L2 NEDD4 binding protein 2-like 2 -0.018155
ANKRD28 ankyrin repeat domain 28 -0.0181353
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0180947
BASP1 brain abundant, membrane attached signal protein 1 -0.0180902
TCP11L1 t-complex 11, testis-specific-like 1 -0.0180416
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0180406
TRAF3 TNF receptor-associated factor 3 -0.0180087
TPCN1 two pore segment channel 1 -0.0179832
SCAMP2 secretory carrier membrane protein 2 -0.0179759
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -0.0179757
LCOR ligand dependent nuclear receptor corepressor -0.0179699
VIM vimentin -0.017937
RPS11 ribosomal protein S11 -0.0179065
CCDC47 coiled-coil domain containing 47 -0.0178947
CCDC138 coiled-coil domain containing 138 -0.0178369
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.0178177
RNF103-CHMP3 RNF103-CHMP3 readthrough -0.0177861
EML2 echinoderm microtubule associated protein like 2 -0.0177719
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.0177702
ETNK1 ethanolamine kinase 1 -0.0176978
FOXK1 forkhead box K1 -0.0176673
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.0176546
ICE1 interactor of little elongation complex ELL subunit 1 -0.0176098
WSB1 WD repeat and SOCS box containing 1 -0.0175939
MYO1E myosin IE -0.0175795
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.0175158
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0175125
TRAPPC10 trafficking protein particle complex 10 -0.0173891
SETDB1 SET domain, bifurcated 1 -0.0173755
SKAP2 src kinase associated phosphoprotein 2 -0.0173631
TJP1 tight junction protein 1 -0.0173392
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 -0.0173031
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0172266
PLCH1 phospholipase C, eta 1 -0.0172065
WDFY1 WD repeat and FYVE domain containing 1 -0.0172054
HAVCR1 hepatitis A virus cellular receptor 1 -0.017204
WWC1 WW and C2 domain containing 1 -0.0171805
KIAA1958 KIAA1958 -0.017161
ATP5MC2 ATP synthase membrane subunit c locus 2 -0.0170879
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0170808
RXYLT1 ribitol xylosyltransferase 1 -0.0170794
EFNA5 ephrin-A5 -0.0170776
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -0.0170589
DROSHA drosha, ribonuclease type III -0.0170468
AHNAK AHNAK nucleoprotein -0.0170035
HLA-E major histocompatibility complex, class I, E -0.016954
CCDC57 coiled-coil domain containing 57 -0.0169292
RPS3 ribosomal protein S3 -0.0168857
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.0168801
SPG11 spastic paraplegia 11 (autosomal recessive) -0.0168573
KATNAL1 katanin p60 subunit A-like 1 -0.0168264
KDM6A lysine (K)-specific demethylase 6A -0.0168253
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0168052
PCGF6 polycomb group ring finger 6 -0.0168034
TMED3 transmembrane emp24 protein transport domain containing 3 -0.0168016
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0167976
MAGT1 magnesium transporter 1 -0.016785
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.0167541
MLPH melanophilin -0.0167398
PNKP polynucleotide kinase 3'-phosphatase -0.0167283
TCP1 t-complex 1 -0.0166779
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.0166562
BRWD1 bromodomain and WD repeat domain containing 1 -0.0166455
TRRAP transformation/transcription domain-associated protein -0.0166287
CYRIB CYFIP related Rac1 interactor B -0.0165993
MSI2 musashi RNA-binding protein 2 -0.0165489
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.0165449
POFUT1 protein O-fucosyltransferase 1 -0.0165363
PCM1 pericentriolar material 1 -0.0165144
FAM114A1 family with sequence similarity 114, member A1 -0.0165124
XPO6 exportin 6 -0.0164774
GON4L gon-4-like (C. elegans) -0.0164718
ZFAND6 zinc finger, AN1-type domain 6 -0.0164574
RPL29 ribosomal protein L29 -0.016448
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 -0.0164098
STOX2 storkhead box 2 -0.0163989
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.016387
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.016382
UNC13B unc-13 homolog B (C. elegans) -0.01637
LIN9 lin-9 DREAM MuvB core complex component -0.0163592
RAN RAN, member RAS oncogene family -0.0163163
FBXO16 F-box protein 16 -0.0163144
ATOSA atos homolog A -0.0162976
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 -0.0162284
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.0162096
YY1AP1 YY1 associated protein 1 -0.0162094
NAT10 N-acetyltransferase 10 (GCN5-related) -0.0162056
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -0.0162055
ZNF573 zinc finger protein 573 -0.0161955
ADCY9 adenylate cyclase 9 -0.0160988
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0160824
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -0.0160707
ZNF518A zinc finger protein 518A -0.0160186
PSD3 pleckstrin and Sec7 domain containing 3 -0.016014
EXOC6 exocyst complex component 6 -0.0159794
LHFPL2 lipoma HMGIC fusion partner-like 2 -0.0158793
CORO1C coronin, actin binding protein, 1C -0.0158789
UBXN7 UBX domain protein 7 -0.0158618
KDM5A lysine (K)-specific demethylase 5A -0.0158554
TRAM1 translocation associated membrane protein 1 -0.0158187
GCN1 GCN1 activator of EIF2AK4 -0.0157955
MDN1 MDN1, midasin homolog (yeast) -0.0157884
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.0157726
PISD phosphatidylserine decarboxylase -0.0157633
DCTN2 dynactin 2 (p50) -0.0157529
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -0.0157223
PER2 period circadian clock 2 -0.0157152
KMT5B lysine methyltransferase 5B -0.0156881
ARF4 ADP-ribosylation factor 4 -0.0156736
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.015671
PTOV1 prostate tumor overexpressed 1 -0.0156677
FA2H fatty acid 2-hydroxylase -0.0156073
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.0155984
KIAA0319 KIAA0319 -0.0155907
RPSA ribosomal protein SA -0.0155766
FKBP5 FK506 binding protein 5 -0.0155618
SSR4 signal sequence receptor, delta -0.0155558
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -0.0155308
CTPS2 CTP synthase 2 -0.0155093
LETMD1 LETM1 domain containing 1 -0.0154974
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0154862
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 -0.0154788
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 -0.0154649
LARS1 leucyl-tRNA synthetase 1 -0.0154499
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0154367
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.015434
STK40 serine/threonine kinase 40 -0.0154227
NUMB numb homolog (Drosophila) -0.0154009
AXL AXL receptor tyrosine kinase -0.0153986
NCOA7 nuclear receptor coactivator 7 -0.0153864
NR2C2 nuclear receptor subfamily 2, group C, member 2 -0.0153763
UBAP2 ubiquitin associated protein 2 -0.0153749
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.015369
EPB41 erythrocyte membrane protein band 4.1 -0.0153422
CASC3 cancer susceptibility candidate 3 -0.0153326
RAB7A RAB7A, member RAS oncogene family -0.0152639
CDK19 cyclin-dependent kinase 19 -0.0152549
MZF1 myeloid zinc finger 1 -0.0152478
PCGF5 polycomb group ring finger 5 -0.0151974
FAM120B family with sequence similarity 120B -0.0151933
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -0.0151734
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 -0.0151672
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0151596
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0151414
GDI2 GDP dissociation inhibitor 2 -0.015118
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.0151138
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -0.0150901
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0150203
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.0150148
ITGB5 integrin, beta 5 -0.0149991
GSPT1 G1 to S phase transition 1 -0.0149726
ATXN7 ataxin 7 -0.0149445
TMEM161B transmembrane protein 161B -0.0149252
INTS2 integrator complex subunit 2 -0.0148449
CEP170 centrosomal protein 170kDa -0.0148246
EIF3B eukaryotic translation initiation factor 3, subunit B -0.0148102
SEC23IP SEC23 interacting protein -0.0148101
TRNP1 TMF1-regulated nuclear protein 1 -0.0147878
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.0147612
APP amyloid beta (A4) precursor protein -0.0147464
ORC3 origin recognition complex, subunit 3 -0.0147419
NFIA nuclear factor I/A -0.0147348
ANXA7 annexin A7 -0.0147153
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -0.0147143
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -0.0147139
OGG1 8-oxoguanine DNA glycosylase -0.0147087
KIRREL1 kirre like nephrin family adhesion molecule 1 -0.0147055
MFSD12 major facilitator superfamily domain containing 12 -0.0146873
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0146827
CNOT12 CCR4-NOT transcription complex subunit 12 -0.0146716
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0146319
MYH9 myosin, heavy chain 9, non-muscle -0.014628
HSPA4L heat shock 70kDa protein 4-like -0.0146261
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.0146255
TTC17 tetratricopeptide repeat domain 17 -0.014599
USP36 ubiquitin specific peptidase 36 -0.0145973
TMX2 thioredoxin-related transmembrane protein 2 -0.0145918
MSH3 mutS homolog 3 -0.014586
AGGF1 angiogenic factor with G patch and FHA domains 1 -0.0145815
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0145755
RHOF ras homolog family member F (in filopodia) -0.0145749
S100A4 S100 calcium binding protein A4 -0.0145689
LRPPRC leucine-rich pentatricopeptide repeat containing -0.014561
PCNX1 pecanex 1 -0.0145436
VRK2 vaccinia related kinase 2 -0.0145395
PHB2 prohibitin 2 -0.0145317
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -0.0145068
TRERF1 transcriptional regulating factor 1 -0.0145032
WNK1 WNK lysine deficient protein kinase 1 -0.0144872
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -0.0144829
PALLD palladin, cytoskeletal associated protein -0.0144277
RNF149 ring finger protein 149 -0.0144265
SERF2 small EDRK-rich factor 2 -0.0143778
MYADM myeloid-associated differentiation marker -0.0143593
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0143496
ALPK2 alpha-kinase 2 -0.0143348
VCP valosin containing protein -0.0143306
YIPF5 Yip1 domain family, member 5 -0.0143218
TBCK TBC1 domain containing kinase -0.0143203
SFPQ splicing factor proline/glutamine-rich -0.0142951
ZNF292 zinc finger protein 292 -0.0142728
UBC ubiquitin C -0.0142663
SKP1 S-phase kinase-associated protein 1 -0.0142575
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 -0.0142573