AAR2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description AAR2 splicing factor homolog (S. cerevisiae)|This gene encodes the homolog of the yeast A1-alpha2 repressin protein that is involved in mRNA splicing. Alternately spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012] (NCBI Entrez Gene Database, 25980)
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Genes

352 genes differentially expressed following the AAR2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 3.26333
NANOS2 nanos homolog 2 (Drosophila) 3.26333
CX3CL1 chemokine (C-X3-C motif) ligand 1 3.26333
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.26333
PON1 paraoxonase 1 3.26333
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 3.26333
GJB3 gap junction protein, beta 3, 31kDa 3.26333
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 3.26333
PAX5 paired box 5 3.26333
APOA2 apolipoprotein A-II 3.26333
LRRTM1 leucine rich repeat transmembrane neuronal 1 3.26333
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.26333
PDILT protein disulfide isomerase-like, testis expressed 3.26333
SLCO1B3 solute carrier organic anion transporter family, member 1B3 3.26333
SRL sarcalumenin 3.26333
TMEM212 transmembrane protein 212 3.26333
TMPRSS11A transmembrane protease, serine 11A 3.26333
AGTR1 angiotensin II receptor, type 1 3.26333
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.26333
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3.26333
MAP3K7CL MAP3K7 C-terminal like 3.26333
FETUB fetuin B 3.26333
RPE65 retinal pigment epithelium-specific protein 65kDa 3.26333
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 3.26333
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 3.26333
FAM181B family with sequence similarity 181, member B 3.26333
PRR29 proline rich 29 3.26333
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 3.26333
TLDC2 TBC/LysM-associated domain containing 2 3.26333
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 3.26333
CD22 CD22 molecule 3.26333
R3HDML R3H domain containing-like 3.26333
OVCH1 ovochymase 1 3.26333
CPLX3 complexin 3 3.26333
ADGB androglobin 3.26333
BSX brain-specific homeobox 3.26333
GMFG glia maturation factor, gamma 3.26333
EDDM3B epididymal protein 3B 3.26333
TMEM71 transmembrane protein 71 3.26333
ZNF221 zinc finger protein 221 3.26333
ADAT3 adenosine deaminase, tRNA-specific 3 3.26333
BMP3 bone morphogenetic protein 3 3.26333
LGALS2 lectin, galactoside-binding, soluble, 2 3.26333
MRGPRX3 MAS-related GPR, member X3 3.26333
SLC22A10 solute carrier family 22, member 10 3.26333
LRTM3 leucine rich repeat transmembrane protein 3 3.26333
KIRREL1 kirre like nephrin family adhesion molecule 1 3.26333
RIPOR1 RHO family interacting cell polarization regulator 1 3.26333
HAO2 hydroxyacid oxidase 2 (long chain) 3.26333
C3AR1 complement component 3a receptor 1 3.26333
PNLIPRP1 pancreatic lipase-related protein 1 3.26333
VN1R2 vomeronasal 1 receptor 2 3.26333
SIM1 single-minded family bHLH transcription factor 1 3.26333
SPEM1 spermatid maturation 1 3.26333
POM121L2 POM121 transmembrane nucleoporin-like 2 3.26333
TENT5C terminal nucleotidyltransferase 5C 3.26333
CCDC198 coiled-coil domain containing 198 3.26333
SPMAP1 sperm microtubule associated protein 1 3.26333
DRC5 dynein regulatory complex subunit 5 3.26333
SPEGNB SPEG neighbor 3.26333
LOC124906010 uncharacterized LOC124906010 3.26333
SPAAR small regulatory polypeptide of amino acid response 3.26333
H4C14 H4 clustered histone 14 3.26333
SERTM2 serine rich and transmembrane domain containing 2 3.26333
DNAAF6 dynein axonemal assembly factor 6 3.26333
TAFA3 TAFA chemokine like family member 3 3.26333
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 3.26333
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 3.26333
ZNF575 zinc finger protein 575 3.26333
TMEM235 transmembrane protein 235 3.26333
CBLN3 cerebellin 3 precursor 3.26333
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 3.26333
SAXO3 stabilizer of axonemal microtubules 3 3.26333
NXPE2 neurexophilin and PC-esterase domain family, member 2 3.26333
ARL5C ADP-ribosylation factor-like 5C 3.26333
PTPRH protein tyrosine phosphatase, receptor type, H 3.26333
PCDHA7 protocadherin alpha 7 3.26333
RUNX3 runt-related transcription factor 3 3.26333
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.26333
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.26333
GATA2 GATA binding protein 2 3.26333
PRDM7 PR domain containing 7 3.26333
MOV10L1 Mov10 RISC complex RNA helicase like 1 3.26333
GDF6 growth differentiation factor 6 3.26333
FRK fyn-related Src family tyrosine kinase 3.26333
PLEK2 pleckstrin 2 3.26333
CELA2A chymotrypsin-like elastase family, member 2A 3.26333
PIWIL3 piwi-like RNA-mediated gene silencing 3 3.26333
OR2A1 olfactory receptor, family 2, subfamily A, member 1 3.26333
NRGN neurogranin (protein kinase C substrate, RC3) 3.26333
COL17A1 collagen, type XVII, alpha 1 3.26333
EXTL2 exostosin-like glycosyltransferase 2 3.26333
RETN resistin 3.26333
MRLN myoregulin 3.26333
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 3.26333
CCL24 chemokine (C-C motif) ligand 24 3.26333
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.26333
PCDHGB4 protocadherin gamma subfamily B, 4 3.26333
KATNBL1 katanin p80 subunit B-like 1 3.26333
PLA2G4D phospholipase A2, group IVD (cytosolic) 3.26333
SDS serine dehydratase 3.26333
HSPB9 heat shock protein, alpha-crystallin-related, B9 3.26333
BOLL boule-like RNA-binding protein 3.26333
TSPAN32 tetraspanin 32 3.26333
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 3.26333
ACKR3 atypical chemokine receptor 3 3.26333
ARHGAP20 Rho GTPase activating protein 20 3.26333
UBXN10 UBX domain protein 10 3.26333
GP5 glycoprotein V (platelet) 3.26333
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing 3.26333
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.26333
EVPLL envoplakin-like 3.26333
SHISA8 shisa family member 8 3.26333
DRD3 dopamine receptor D3 3.26333
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 3.26333
PAGE4 P antigen family, member 4 (prostate associated) 3.26333
CHIT1 chitinase 1 (chitotriosidase) 3.26333
CPA2 carboxypeptidase A2 (pancreatic) 3.26333
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.26333
C11ORF16 chromosome 11 open reading frame 16 3.26333
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.26333
EMX2 empty spiracles homeobox 2 3.26333
CTAGE4 CTAGE family, member 4 3.26333
CLRN1 clarin 1 3.26333
CRYBB2 crystallin, beta B2 3.26333
AQP7 aquaporin 7 3.26333
TPPP3 tubulin polymerization-promoting protein family member 3 3.26333
SLITRK1 SLIT and NTRK-like family, member 1 3.26333
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 3.26333
NEUROD2 neuronal differentiation 2 3.26333
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.26333
SYTL4 synaptotagmin-like 4 3.26333
PTPN7 protein tyrosine phosphatase, non-receptor type 7 3.26333
C10ORF90 chromosome 10 open reading frame 90 3.26333
AGBL4 ATP/GTP binding protein-like 4 3.26333
ASCL3 achaete-scute family bHLH transcription factor 3 3.26333
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 3.26333
CCNA1 cyclin A1 3.26333
PEBP4 phosphatidylethanolamine-binding protein 4 3.26333
TGM3 transglutaminase 3 3.26333
GREM1 gremlin 1, DAN family BMP antagonist 3.26333
PGM5 phosphoglucomutase 5 3.26333
TMEM215 transmembrane protein 215 3.26333
PDK4 pyruvate dehydrogenase kinase, isozyme 4 3.26333
CHRDL2 chordin-like 2 3.26333
ASCL2 achaete-scute family bHLH transcription factor 2 3.26333
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 3.26333
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 3.26333
LRRC25 leucine rich repeat containing 25 3.26333
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 3.26333
PXT1 peroxisomal, testis specific 1 3.26333
ERVV-2 endogenous retrovirus group V, member 2 3.26333
RERGL RERG/RAS-like 3.26333
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.26333
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 3.26333
POTEI POTE ankyrin domain family, member I 3.26333
SLC25A48 solute carrier family 25, member 48 3.24215
FAM110D family with sequence similarity 110, member D 3.15491
MICALL2 MICAL-like 2 3.15491
TAPBPL TAP binding protein-like 3.15491
NAGS N-acetylglutamate synthase 3.15491
RAMACL RNA guanine-7 methyltransferase activating subunit like 3.15491
NUTM2E NUT family member 2E 3.15491
SPACA9 sperm acrosome associated 9 3.15491
INHBE inhibin, beta E 3.15491
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 3.03193
RABIF RAB interacting factor 2.97275
TM7SF2 transmembrane 7 superfamily member 2 2.93457
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.90787
ATG101 autophagy related 101 2.8554
DNAH2 dynein, axonemal, heavy chain 2 2.82862
ASPHD2 aspartate beta-hydroxylase domain containing 2 2.77511
TICRR TOPBP1-interacting checkpoint and replication regulator 2.68773
DEDD death effector domain containing 2.68608
DRC11 dynein regulatory complex subunit 11 2.64881
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.62983
FGD4 FYVE, RhoGEF and PH domain containing 4 2.53678
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.52249
IRF7 interferon regulatory factor 7 2.49245
RP1L1 retinitis pigmentosa 1-like 1 2.49245
ACSL6 acyl-CoA synthetase long-chain family member 6 2.49225
PYCARD PYD and CARD domain containing 2.48837
CPT1C carnitine palmitoyltransferase 1C 2.4725
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 2.46587
NPTX1 neuronal pentraxin I 2.3497
SYS1 Sys1 golgi trafficking protein 2.34591
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 2.32751
ITM2C integral membrane protein 2C 2.32547
TRAPPC3 trafficking protein particle complex 3 2.30824
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.28643
DYNAP dynactin associated protein 2.2847
MYZAP myocardial zonula adherens protein 2.2847
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.27649
CA11 carbonic anhydrase XI 2.2624
SAP18 Sin3A-associated protein, 18kDa 2.23206
PELI1 pellino E3 ubiquitin protein ligase 1 2.23206
CROT carnitine O-octanoyltransferase 2.23117
TRAPPC2 trafficking protein particle complex 2 2.22957
KIN Kin17 DNA and RNA binding protein 2.22481
RAB9A RAB9A, member RAS oncogene family 2.21549
ACD adrenocortical dysplasia homolog (mouse) 2.18786
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2.17671
VDAC3 voltage-dependent anion channel 3 2.17047
RAB8A RAB8A, member RAS oncogene family 2.16071
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.16071
ZDHHC11B zinc finger, DHHC-type containing 11B 2.16071
TNC tenascin C 2.16071
FAM24B family with sequence similarity 24, member B 2.16071
HCST hematopoietic cell signal transducer 2.16071
CSRNP1 cysteine-serine-rich nuclear protein 1 2.16071
OAF OAF homolog (Drosophila) 2.16071
WASHC4 WASH complex subunit 4 2.15623
TET1 tet methylcytosine dioxygenase 1 2.13888
ACYP1 acylphosphatase 1, erythrocyte (common) type 2.13437
TRIM45 tripartite motif containing 45 2.10771
PIAS4 protein inhibitor of activated STAT, 4 2.10771
TADA3 transcriptional adaptor 3 2.09473
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.08168
MACROH2A1 macroH2A.1 histone 2.08168
THAP5 THAP domain containing 5 2.08168
SDC1 syndecan 1 2.06038
RTL8B retrotransposon Gag like 8B 2.05769
SLC22A23 solute carrier family 22, member 23 2.05769
CCDC194 coiled-coil domain containing 194 2.05769
LOXHD1 lipoxygenase homology domains 1 2.05769
DPY30 dpy-30 homolog (C. elegans) 2.05218
HM13 histocompatibility (minor) 13 2.03376
PDE10A phosphodiesterase 10A 2.01906
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.00205

decreased expression

Symbol Name Standardized Value
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.26333
MPZL2 myelin protein zero-like 2 -3.26333
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1 -3.26333
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -3.26333
HAS1 hyaluronan synthase 1 -3.26333
NPPA natriuretic peptide A -3.26333
PWWP2A PWWP domain containing 2A -3.26333
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.26333
GPR20 G protein-coupled receptor 20 -3.26333
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -3.26333
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 -3.26333
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -3.26333
SCN7A sodium channel, voltage gated, type VII alpha subunit -3.26333
C1ORF53 chromosome 1 open reading frame 53 -3.26333
ZNF570 zinc finger protein 570 -3.26333
MYL5 myosin, light chain 5, regulatory -3.26333
ULBP3 UL16 binding protein 3 -3.26333
PSD4 pleckstrin and Sec7 domain containing 4 -3.26333
NR1I2 nuclear receptor subfamily 1, group I, member 2 -3.26333
IL32 interleukin 32 -3.26333
TNS2 tensin 2 -3.26333
ESR1 estrogen receptor 1 -3.26333
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -3.26333
TICAM1 toll-like receptor adaptor molecule 1 -3.26333
TTN titin -3.26333
NRP1 neuropilin 1 -3.26333
IGSF6 immunoglobulin superfamily, member 6 -3.26333
H2BC12 H2B clustered histone 12 -3.26333
MNT MAX network transcriptional repressor -3.26333
BTN3A3 butyrophilin, subfamily 3, member A3 -3.26333
SLC25A45 solute carrier family 25, member 45 -3.26333
SPACDR sperm acrosome developmental regulator -3.26333
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.26333
ALKAL1 ALK and LTK ligand 1 -3.26333
PON3 paraoxonase 3 -3.26333
DEFB131B defensin beta 131B -3.26333
ZC3H11A zinc finger CCCH-type containing 11A -3.26333
CFAP119 cilia and flagella associated protein 119 -3.26333
LRRC55 leucine rich repeat containing 55 -3.26333
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 -3.26333
FAM186B family with sequence similarity 186, member B -3.26333
FAM153A family with sequence similarity 153, member A -3.26333
PDZD7 PDZ domain containing 7 -3.26333
BGN biglycan -3.26333
CXORF58 chromosome X open reading frame 58 -3.26333
PDZRN4 PDZ domain containing ring finger 4 -3.26333
ADRB2 adrenoceptor beta 2, surface -3.26333
RXRA retinoid X receptor, alpha -3.24215
ADRA1D adrenoceptor alpha 1D -3.15491
FMO5 flavin containing monooxygenase 5 -3.15491
RNF207 ring finger protein 207 -3.15491
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.15491
JAKMIP1 janus kinase and microtubule interacting protein 1 -3.15491
SIRT1 sirtuin 1 -3.04234
SERINC1 serine incorporator 1 -3.00923
LPCAT4 lysophosphatidylcholine acyltransferase 4 -2.9364
ZNF653 zinc finger protein 653 -2.90868
DCAF16 DDB1 and CUL4 associated factor 16 -2.8543
C8ORF76 chromosome 8 open reading frame 76 -2.74576
NEK5 NIMA-related kinase 5 -2.71122
HTRA3 HtrA serine peptidase 3 -2.68092
CAPRIN1 cell cycle associated protein 1 -2.65572
FDPS farnesyl diphosphate synthase -2.60997
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 -2.53678
ZNF207 zinc finger protein 207 -2.5064
GSPT2 G1 to S phase transition 2 -2.48896
FAT2 FAT atypical cadherin 2 -2.4827
ZNF524 zinc finger protein 524 -2.4827
ZFPM1 zinc finger protein, FOG family member 1 -2.4827
GAB3 GRB2-associated binding protein 3 -2.4827
PRKD1 protein kinase D1 -2.45959
RERG RAS-like, estrogen-regulated, growth inhibitor -2.44384
NUTM1 NUT midline carcinoma, family member 1 -2.44384
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -2.43869
TMEM126A transmembrane protein 126A -2.42747
ZNF419 zinc finger protein 419 -2.42747
FNBP1 formin binding protein 1 -2.39976
CBFB core-binding factor, beta subunit -2.39324
CREB3L4 cAMP responsive element binding protein 3-like 4 -2.35365
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 -2.35365
ZNF607 zinc finger protein 607 -2.35352
KATNA1 katanin p60 (ATPase containing) subunit A 1 -2.35352
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -2.30634
ING1 inhibitor of growth family, member 1 -2.29786
HAP1 huntingtin-associated protein 1 -2.28643
TMEM138 transmembrane protein 138 -2.28643
CDRT4 CMT1A duplicated region transcript 4 -2.28643
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.28357
SEC24B SEC24 family member B -2.23408
TERT telomerase reverse transcriptase -2.20436
TCEAL4 transcription elongation factor A (SII)-like 4 -2.20361
H2BC18 H2B clustered histone 18 -2.19107
APP-DT APP divergent transcript -2.18956
CDT1 chromatin licensing and DNA replication factor 1 -2.18274
ADCK5 aarF domain containing kinase 5 -2.18053
EGFL8 EGF-like-domain, multiple 8 -2.18053
SEPHS2 selenophosphate synthetase 2 -2.17325
NCOA2 nuclear receptor coactivator 2 -2.16736
CENPI centromere protein I -2.16736
LUC7L3 LUC7-like 3 (S. cerevisiae) -2.1673
CABP1 calcium binding protein 1 -2.16071
NBPF26 neuroblastoma breakpoint family, member 26 -2.15623
ARRB1 arrestin, beta 1 -2.14339
LRMDA leucine rich melanocyte differentiation associated -2.13263
NUMB numb homolog (Drosophila) -2.09473
ZNF2 zinc finger protein 2 -2.09473
SDC3 syndecan 3 -2.05769
ZFAND2A zinc finger, AN1-type domain 2A -2.05769
USP24 ubiquitin specific peptidase 24 -2.05228
WLS wntless Wnt ligand secretion mediator -2.04197
EYA3 EYA transcriptional coactivator and phosphatase 3 -2.03376
CSNK1G1 casein kinase 1, gamma 1 -2.0131
ROR2 receptor tyrosine kinase-like orphan receptor 2 -2.00412
PDCL3 phosducin-like 3 -2.00377
NFIA nuclear factor I/A -2.00205
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -2.00103
CELA2B chymotrypsin-like elastase family, member 2B -2.00103
HK1 hexokinase 1 -2.00103
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.00103
FBN3 fibrillin 3 -2.00103
RBP1 retinol binding protein 1, cellular -2.00103
PRXL2B peroxiredoxin like 2B -2.00103
LRRC17 leucine rich repeat containing 17 -2.00103