AARD Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description alanine and arginine rich domain containing protein| (NCBI Entrez Gene Database, 441376)
Similar Terms
Downloads & Tools

Genes

340 genes differentially expressed following the AARD gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
APOOL apolipoprotein O-like 3.65091
OLIG3 oligodendrocyte transcription factor 3 3.65091
ASB10 ankyrin repeat and SOCS box containing 10 3.65091
OLFM4 olfactomedin 4 3.65091
SLC30A2 solute carrier family 30 (zinc transporter), member 2 3.65091
SLC30A4 solute carrier family 30 (zinc transporter), member 4 3.65091
NEU4 sialidase 4 3.65091
ASPA aspartoacylase 3.65091
TRPV3 transient receptor potential cation channel, subfamily V, member 3 3.65091
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.65091
PAX7 paired box 7 3.65091
FFAR4 free fatty acid receptor 4 3.65091
IZUMO3 IZUMO family member 3 3.65091
CD19 CD19 molecule 3.65091
BTN1A1 butyrophilin, subfamily 1, member A1 3.65091
MGAM2 maltase-glucoamylase 2 (putative) 3.65091
ZNF662 zinc finger protein 662 3.65091
PDYN prodynorphin 3.65091
SSTR1 somatostatin receptor 1 3.65091
RIMBP2 RIMS binding protein 2 3.65091
WT1 Wilms tumor 1 3.65091
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.65091
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 3.65091
RGPD4 RANBP2-like and GRIP domain containing 4 3.65091
STEAP4 STEAP family member 4 3.65091
SPAG8 sperm associated antigen 8 3.65091
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.65091
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 3.65091
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 3.65091
FGF7 fibroblast growth factor 7 3.65091
PRSS22 protease, serine, 22 3.65091
SMCO1 single-pass membrane protein with coiled-coil domains 1 3.65091
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.65091
PRDM8 PR domain containing 8 3.65091
TPPP tubulin polymerization promoting protein 3.65091
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.65091
RLN3 relaxin 3 3.65091
TTLL2 tubulin tyrosine ligase-like family member 2 3.65091
DLX4 distal-less homeobox 4 3.65091
ADAT3 adenosine deaminase, tRNA-specific 3 3.65091
ATOH7 atonal homolog 7 (Drosophila) 3.65091
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 3.65091
OR2B11 olfactory receptor, family 2, subfamily B, member 11 3.65091
C2ORF78 chromosome 2 open reading frame 78 3.65091
FAM81B family with sequence similarity 81, member B 3.65091
SCPPPQ1 secretory calcium-binding phosphoprotein proline-glutamine rich 1 3.65091
SPRR2E small proline-rich protein 2E 3.65091
FIMP1 fertilization-influencing membrane protein 1 3.65091
LELP1 late cornified envelope-like proline-rich 1 3.65091
IQCF3 IQ motif containing F3 3.65091
ADRB3 adrenoceptor beta 3 3.65091
BDKRB1 bradykinin receptor B1 3.65091
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.65091
OR52E5 olfactory receptor, family 52, subfamily E, member 5 3.65091
GPR37L1 G protein-coupled receptor 37 like 1 3.65091
ZNF726 zinc finger protein 726 3.65091
HAO2 hydroxyacid oxidase 2 (long chain) 3.65091
SPMIP10 sperm microtubule inner protein 10 3.65091
PRR20G proline rich 20G 3.65091
NOTCH2NLB notch 2 N-terminal like B 3.65091
TMT1B thiol methyltransferase 1B 3.65091
CD8B2 CD8b2 molecule 3.65091
RHEX regulator of hemoglobinization and erythroid cell expansion 3.65091
H3C14 H3 clustered histone 14 3.65091
CALHM4 calcium homeostasis modulator family member 4 3.65091
ERVW-1 endogenous retrovirus group W, member 1 3.65091
KRTAP7-1 keratin associated protein 7-1 (gene/pseudogene) 3.65091
DYNLRB2 dynein, light chain, roadblock-type 2 3.65091
C15ORF62 chromosome 15 open reading frame 62 3.65091
ZSWIM2 zinc finger, SWIM-type containing 2 3.65091
PCDHB13 protocadherin beta 13 3.65091
OASL 2'-5'-oligoadenylate synthetase-like 3.65091
RLBP1 retinaldehyde binding protein 1 3.65091
GRXCR1 glutaredoxin, cysteine rich 1 3.65091
HBA2 hemoglobin, alpha 2 3.65091
GPR4 G protein-coupled receptor 4 3.65091
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 3.65091
STKLD1 serine/threonine kinase-like domain containing 1 3.65091
MAG myelin associated glycoprotein 3.65091
IL31RA interleukin 31 receptor A 3.65091
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.65091
TACR2 tachykinin receptor 2 3.65091
PIWIL3 piwi-like RNA-mediated gene silencing 3 3.65091
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.65091
KLRF2 killer cell lectin-like receptor subfamily F, member 2 3.65091
SLAMF1 signaling lymphocytic activation molecule family member 1 3.65091
C1ORF162 chromosome 1 open reading frame 162 3.65091
CATSPER3 cation channel, sperm associated 3 3.65091
CALCA calcitonin-related polypeptide alpha 3.65091
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 3.65091
KLF2 Kruppel-like factor 2 3.65091
IL11 interleukin 11 3.65091
FNDC8 fibronectin type III domain containing 8 3.65091
PCDHGB2 protocadherin gamma subfamily B, 2 3.65091
PDZRN4 PDZ domain containing ring finger 4 3.65091
HP haptoglobin 3.65091
STAB1 stabilin 1 3.65091
PHOSPHO1 phosphatase, orphan 1 3.65091
TBPL2 TATA box binding protein like 2 3.65091
ITGA8 integrin, alpha 8 3.65091
PRSS57 protease, serine, 57 3.65091
PRSS51 protease, serine, 51 3.65091
CHIT1 chitinase 1 (chitotriosidase) 3.65091
PRR35 proline rich 35 3.65091
CRYBA1 crystallin, beta A1 3.65091
MYOD1 myogenic differentiation 1 3.65091
CCL27 chemokine (C-C motif) ligand 27 3.65091
OAZ3 ornithine decarboxylase antizyme 3 3.65091
CALHM2 calcium homeostasis modulator 2 3.65091
DPRX divergent-paired related homeobox 3.65091
C11ORF91 chromosome 11 open reading frame 91 3.65091
CALHM3 calcium homeostasis modulator 3 3.65091
NPBWR1 neuropeptides B/W receptor 1 3.65091
MAB21L3 mab-21-like 3 (C. elegans) 3.65091
RGSL1 regulator of G-protein signaling like 1 3.65091
PCDHGA7 protocadherin gamma subfamily A, 7 3.65091
OPRK1 opioid receptor, kappa 1 3.65091
EVPLL envoplakin-like 3.65091
CNTF ciliary neurotrophic factor 3.65091
VWA3B von Willebrand factor A domain containing 3B 3.65091
TMEM132E transmembrane protein 132E 3.65091
MAEL maelstrom spermatogenic transposon silencer 3.65091
TF transferrin 3.65091
SLC36A3 solute carrier family 36, member 3 3.65091
CERKL ceramide kinase-like 3.65091
ERVV-1 endogenous retrovirus group V, member 1 3.65091
GPR150 G protein-coupled receptor 150 3.65091
POU4F1 POU class 4 homeobox 1 3.65091
POPDC2 popeye domain containing 2 3.65091
ASCL3 achaete-scute family bHLH transcription factor 3 3.65091
IRX4 iroquois homeobox 4 3.65091
DCST1 DC-STAMP domain containing 1 3.65091
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.65091
FAM151A family with sequence similarity 151, member A 3.65091
ADAM18 ADAM metallopeptidase domain 18 3.65091
WFDC13 WAP four-disulfide core domain 13 3.65091
CLEC18B C-type lectin domain family 18, member B 3.65091
ZNF831 zinc finger protein 831 3.65091
HIGD1C HIG1 hypoxia inducible domain family, member 1C 3.65091
NOTCH4 notch 4 3.65091
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 3.65091
MAGEA9B melanoma antigen family A9B 3.65091
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 3.65091
GCM1 glial cells missing homolog 1 (Drosophila) 3.65091
POTEJ POTE ankyrin domain family, member J 3.65091
ITPKA inositol-trisphosphate 3-kinase A 3.65091
MYLK2 myosin light chain kinase 2 3.65091
CHAT choline O-acetyltransferase 3.65091
NOBOX NOBOX oogenesis homeobox 3.65091
PTCRA pre T-cell antigen receptor alpha 3.65091
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 3.65091
FAM222A family with sequence similarity 222, member A 3.58623
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 3.58623
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 3.50164
ZSCAN26 zinc finger and SCAN domain containing 26 3.41471
TCF4 transcription factor 4 3.32969
LOC102723564 uncharacterized LOC102723564 3.31324
WDR31 WD repeat domain 31 3.31324
NEGR1 neuronal growth regulator 1 3.02951
LRRC66 leucine rich repeat containing 66 2.91657
CSMD3 CUB and Sushi multiple domains 3 2.91114
USP47 ubiquitin specific peptidase 47 2.80215
REPS2 RALBP1 associated Eps domain containing 2 2.79373
CC2D1A coiled-coil and C2 domain containing 1A 2.77818
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.77707
NRL neural retina leucine zipper 2.75347
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.71198
ASMT acetylserotonin O-methyltransferase 2.71198
SLC51B solute carrier family 51, beta subunit 2.71198
IRF8 interferon regulatory factor 8 2.71198
C16ORF54 chromosome 16 open reading frame 54 2.71198
RELL2 RELT-like 2 2.6944
ZNF546 zinc finger protein 546 2.66528
ZNF415 zinc finger protein 415 2.66038
IL3RA interleukin 3 receptor, alpha (low affinity) 2.64747
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.63471
GK glycerol kinase 2.62079
SKIC3 SKI3 subunit of superkiller complex 2.58184
CFAP46 cilia and flagella associated protein 46 2.57478
XPC xeroderma pigmentosum, complementation group C 2.5633
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 2.5621
MEIG1 meiosis/spermiogenesis associated 1 2.5621
ZAR1L zygote arrest 1-like 2.5621
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.50615
RBM26 RNA binding motif protein 26 2.48536
CFAP157 cilia and flagella associated protein 157 2.42358
HLA-E major histocompatibility complex, class I, E 2.41385
ROR1 receptor tyrosine kinase-like orphan receptor 1 2.40727
ETV3L ets variant 3-like 2.39032
CDC20B cell division cycle 20B 2.39032
TMEM86B transmembrane protein 86B 2.36212
ASB6 ankyrin repeat and SOCS box containing 6 2.34728
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.34685
NIM1K NIM1 serine/threonine protein kinase 2.33381
ZNF561 zinc finger protein 561 2.31881
PPP1R21 protein phosphatase 1, regulatory subunit 21 2.31343
SCN2A sodium channel, voltage gated, type II alpha subunit 2.28912
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 2.26081
LDB2 LIM domain binding 2 2.25999
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.25624
MINDY2 MINDY lysine 48 deubiquitinase 2 2.23848
CCDC13 coiled-coil domain containing 13 2.22969
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 2.16852
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.15996
SSH1 slingshot protein phosphatase 1 2.15018
MAP3K2 mitogen-activated protein kinase kinase kinase 2 2.1387
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 2.13865
TPP1 tripeptidyl peptidase I 2.12296
LCOR ligand dependent nuclear receptor corepressor 2.10183
LIPI lipase, member I 2.10048
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 2.08591
CFAP221 cilia and flagella associated protein 221 2.07428
NIPBL Nipped-B homolog (Drosophila) 2.05545
STOX2 storkhead box 2 2.04565
TLR5 toll-like receptor 5 2.04114
NLRC3 NLR family, CARD domain containing 3 2.04114
ZNF333 zinc finger protein 333 2.03925
PDE4B phosphodiesterase 4B, cAMP-specific 2.01748
MBD1 methyl-CpG binding domain protein 1 2.01673
TRIM21 tripartite motif containing 21 2.0009
PDZD11 PDZ domain containing 11 2.00035

decreased expression

Symbol Name Standardized Value
RPS9 ribosomal protein S9 -3.65091
ATAD3C ATPase family, AAA domain containing 3C -3.65091
ADGRA2 adhesion G protein-coupled receptor A2 -3.65091
FAM24B family with sequence similarity 24, member B -3.65091
WIF1 WNT inhibitory factor 1 -3.65091
LHX6 LIM homeobox 6 -3.5562
ADAM29 ADAM metallopeptidase domain 29 -3.5562
THEM6 thioesterase superfamily member 6 -3.5562
MYORG myogenesis regulating glycosidase (putative) -3.5562
CCDC154 coiled-coil domain containing 154 -3.5562
ARHGAP20 Rho GTPase activating protein 20 -3.5562
ERICH6 glutamate-rich 6 -3.5562
ARR3 arrestin 3, retinal (X-arrestin) -3.5562
CIMAP2 ciliary microtubule associated protein 2 -3.5562
SLC16A6 solute carrier family 16, member 6 -3.5562
ALX4 ALX homeobox 4 -3.5562
RHCG Rh family, C glycoprotein -3.5562
PARVG parvin, gamma -3.5562
C1QL3 complement component 1, q subcomponent-like 3 -3.5562
NPIPB9 nuclear pore complex interacting protein family, member B9 -3.5562
TUBA3D tubulin, alpha 3d -3.5562
ZEB2 zinc finger E-box binding homeobox 2 -3.5562
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like -3.5562
SH2D6 SH2 domain containing 6 -3.5562
OLFML1 olfactomedin-like 1 -3.5562
POU2AF1 POU class 2 associating factor 1 -3.5562
TM4SF19 transmembrane 4 L six family member 19 -3.5562
VWA3A von Willebrand factor A domain containing 3A -3.5562
KLK6 kallikrein-related peptidase 6 -3.5562
CFAP126 cilia and flagella associated protein 126 -3.5562
KLF4 Kruppel-like factor 4 (gut) -3.5562
LMOD2 leiomodin 2 (cardiac) -3.5562
ADCY4 adenylate cyclase 4 -3.5562
FCRLB Fc receptor-like B -3.5562
UPK1B uroplakin 1B -3.5562
HIST1H2BI histone cluster 1, H2bi -3.44995
RUMY3 RUMY family member 3 -3.44995
HFE hemochromatosis -3.44995
EID1 EP300 interacting inhibitor of differentiation 1 -3.29195
TROAP trophinin associated protein -3.28505
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.18651
CSNK1E casein kinase 1, epsilon -3.12842
PTPRF protein tyrosine phosphatase, receptor type, F -2.90407
LRRC39 leucine rich repeat containing 39 -2.90083
PSPN persephin -2.90083
AQP5 aquaporin 5 -2.87109
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 -2.86946
XIRP2 xin actin binding repeat containing 2 -2.83577
TTC21A tetratricopeptide repeat domain 21A -2.83577
CISD1 CDGSH iron sulfur domain 1 -2.80253
ZMIZ1 zinc finger, MIZ-type containing 1 -2.78694
RNF144B ring finger protein 144B -2.7319
ARF5 ADP-ribosylation factor 5 -2.67916
VGLL3 vestigial-like family member 3 -2.66646
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.64099
FBXW5 F-box and WD repeat domain containing 5 -2.62247
MTRF1L mitochondrial translational release factor 1-like -2.57405
MT1G metallothionein 1G -2.57294
PCNA proliferating cell nuclear antigen -2.5621
PGD phosphogluconate dehydrogenase -2.56185
GRID1 glutamate receptor, ionotropic, delta 1 -2.54956
NPDC1 neural proliferation, differentiation and control, 1 -2.54778
CCNG2 cyclin G2 -2.54778
HTATSF1 HIV-1 Tat specific factor 1 -2.53472
MRPL1 mitochondrial ribosomal protein L1 -2.53368
INA internexin neuronal intermediate filament protein, alpha -2.50615
TSKU tsukushi, small leucine rich proteoglycan -2.48536
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.47411
DGAT2 diacylglycerol O-acyltransferase 2 -2.4725
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -2.46754
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -2.46754
MOSPD2 motile sperm domain containing 2 -2.46754
IFI27L2 interferon, alpha-inducible protein 27-like 2 -2.46754
GRM2 glutamate receptor, metabotropic 2 -2.38942
CNTN3 contactin 3 (plasmacytoma associated) -2.38942
VSTM2A V-set and transmembrane domain containing 2A -2.38942
MATN4 matrilin 4 -2.38942
C20ORF204 chromosome 20 open reading frame 204 -2.38942
HHIPL1 HHIP-like 1 -2.37274
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.34822
ADRA2B adrenoceptor alpha 2B -2.34686
CYS1 cystin 1 -2.32105
CIDEB cell death-inducing DFFA-like effector b -2.32105
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -2.31118
SPOCD1 SPOC domain containing 1 -2.30289
SNCG synuclein, gamma (breast cancer-specific protein 1) -2.29009
GPHA2 glycoprotein hormone alpha 2 -2.26972
TUBGCP5 tubulin, gamma complex associated protein 5 -2.26972
RASGRP4 RAS guanyl releasing protein 4 -2.26972
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 -2.2553
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.2553
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 -2.2553
CCS copper chaperone for superoxide dismutase -2.22445
GPR82 G protein-coupled receptor 82 -2.22018
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -2.21507
TMEM14B transmembrane protein 14B -2.19852
PHRF1 PHD and ring finger domains 1 -2.19449
KPNA6 karyopherin alpha 6 (importin alpha 7) -2.17227
MTA3 metastasis associated 1 family, member 3 -2.15828
IP6K2 inositol hexakisphosphate kinase 2 -2.15562
CAND2 cullin-associated and neddylation-dissociated 2 (putative) -2.1543
GIGYF1 GRB10 interacting GYF protein 1 -2.13003
DPPA2 developmental pluripotency associated 2 -2.12748
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -2.11403
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.11403
TRAPPC3 trafficking protein particle complex 3 -2.11403
GSTM3 glutathione S-transferase mu 3 (brain) -2.11376
SNX10 sorting nexin 10 -2.11376
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.11376
EXT2 exostosin glycosyltransferase 2 -2.10616
NAIP NLR family, apoptosis inhibitory protein -2.09542
MOV10 Mov10 RISC complex RNA helicase -2.086
FASN fatty acid synthase -2.07096
BHLHE41 basic helix-loop-helix family, member e41 -2.06631
MGME1 mitochondrial genome maintenance exonuclease 1 -2.05883
UFD1 ubiquitin recognition factor in ER associated degradation 1 -2.03736
RNF10 ring finger protein 10 -2.01748
RAB42 RAB42, member RAS oncogene family -2.01673
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.0009