AATF Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description apoptosis antagonizing transcription factor|The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 26574)
External Link http://www.ncbi.nlm.nih.gov/gene/26574
Similar Terms
Downloads & Tools

Genes

42 interacting proteins for AATF from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
CAND1 cullin-associated and neddylation-dissociated 1
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CPD carboxypeptidase D
DAPK3 death-associated protein kinase 3
DAZAP2 DAZ associated protein 2
E2F1 E2F transcription factor 1
EFNB3 ephrin-B3
HNF4A hepatocyte nuclear factor 4, alpha
LDOC1 leucine zipper, down-regulated in cancer 1
LIN28A lin-28 homolog A (C. elegans)
LZTR1 leucine-zipper-like transcription regulator 1
MAGED1 melanoma antigen family D1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MPHOSPH6 M-phase phosphoprotein 6
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NRF1 nuclear respiratory factor 1
PAWR PRKC, apoptosis, WT1, regulator
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SIRT7 sirtuin 7
SMAD3 SMAD family member 3
SP1 Sp1 transcription factor
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SUMO2 small ubiquitin-like modifier 2
TSG101 tumor susceptibility 101
UBC ubiquitin C
UBD ubiquitin D
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZNF468 zinc finger protein 468