| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ABL proto-oncogene 1, non-receptor tyrosine kinase|This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014] (NCBI Entrez Gene Database, 25) |
| External Link | https://ncbi.nlm.nih.gov/gene/25 |
| Similar Terms | |
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499 genes differentially expressed following the ABL1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00733851 |
| BEX1 | brain expressed, X-linked 1 | 0.00712143 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00664868 |
| FABP7 | fatty acid binding protein 7, brain | 0.00661142 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00595733 |
| SFTPB | surfactant protein B | 0.00573221 |
| FGG | fibrinogen gamma chain | 0.00533226 |
| HOPX | HOP homeobox | 0.00508015 |
| A2M | alpha-2-macroglobulin | 0.00499898 |
| MPO | myeloperoxidase | 0.00498546 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00486019 |
| SFTPD | surfactant protein D | 0.00485396 |
| FGA | fibrinogen alpha chain | 0.0048423 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00474926 |
| SFTPA2 | surfactant protein A2 | 0.00468061 |
| POSTN | periostin, osteoblast specific factor | 0.00464899 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00458839 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00456604 |
| TNS3 | tensin 3 | 0.00447699 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00443521 |
| APOD | apolipoprotein D | 0.00439114 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00434917 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00425645 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00422202 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00421162 |
| PODXL | podocalyxin-like | 0.00420006 |
| MGP | matrix Gla protein | 0.00408969 |
| KRT6A | keratin 6A, type II | 0.00403802 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.00402299 |
| DMD | dystrophin | 0.00400967 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00399264 |
| PDE8B | phosphodiesterase 8B | 0.00398772 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00396519 |
| EHD3 | EH-domain containing 3 | 0.00392856 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00392455 |
| H2AFV | H2A histone family, member V | 0.00391626 |
| MAL | mal, T-cell differentiation protein | 0.00390743 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00389062 |
| TCTA | T-cell leukemia translocation altered | 0.00386903 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.00385436 |
| LTA4H | leukotriene A4 hydrolase | 0.00381028 |
| PCNA | proliferating cell nuclear antigen | 0.00380093 |
| SNX5 | sorting nexin 5 | 0.00379293 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00372331 |
| KRT14 | keratin 14, type I | 0.00371866 |
| DUOX1 | dual oxidase 1 | 0.00368822 |
| SFTPC | surfactant protein C | 0.00367346 |
| CD200 | CD200 molecule | 0.00366807 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.00366287 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00365376 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.00360563 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00360213 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00359052 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00358074 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00355373 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00355072 |
| GPI | glucose-6-phosphate isomerase | 0.00353265 |
| CES1 | carboxylesterase 1 | 0.00351932 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00348975 |
| COG2 | component of oligomeric golgi complex 2 | 0.00348477 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00348026 |
| KRT13 | keratin 13, type I | 0.00347455 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00344098 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00343539 |
| APOC1 | apolipoprotein C-I | 0.00343501 |
| DPP8 | dipeptidyl-peptidase 8 | 0.00341663 |
| CD93 | CD93 molecule | 0.00341603 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.00341223 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0034058 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00333757 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00332271 |
| CHRDL1 | chordin-like 1 | 0.00331552 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00329815 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00328533 |
| RRBP1 | ribosome binding protein 1 | 0.00327397 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00326502 |
| CRYAB | crystallin, alpha B | 0.00324711 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00323747 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00322896 |
| FOLR1 | folate receptor 1 (adult) | 0.0032279 |
| SNX11 | sorting nexin 11 | 0.0032138 |
| RAPSN | receptor-associated protein of the synapse | 0.00320866 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00320797 |
| RGS5 | regulator of G-protein signaling 5 | 0.00320748 |
| GAB2 | GRB2-associated binding protein 2 | 0.00320269 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00319738 |
| GNAS | GNAS complex locus | 0.0031969 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00318792 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.00318723 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.0031869 |
| CS | citrate synthase | 0.00318584 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00318542 |
| NOTCH2 | notch 2 | 0.00314551 |
| KRT5 | keratin 5, type II | 0.00313628 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0031341 |
| TALDO1 | transaldolase 1 | 0.00312356 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.0030996 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00309928 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00309397 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00309155 |
| PGC | progastricsin (pepsinogen C) | 0.0030858 |
| PLA1A | phospholipase A1 member A | 0.0030558 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00304319 |
| EDNRB | endothelin receptor type B | 0.00303665 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00303449 |
| TNNC1 | troponin C type 1 (slow) | 0.00302055 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00300649 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00300213 |
| NDRG4 | NDRG family member 4 | 0.00299331 |
| ETV5 | ets variant 5 | 0.00297715 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00297576 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00297321 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00297298 |
| PRAME | preferentially expressed antigen in melanoma | 0.00297046 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00297005 |
| OXTR | oxytocin receptor | 0.00296457 |
| DNTT | DNA nucleotidylexotransferase | 0.00295488 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.00295363 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00295197 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00294686 |
| TGM2 | transglutaminase 2 | 0.00293844 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00293364 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00291958 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0029145 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00290844 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00290297 |
| HP | haptoglobin | 0.00289829 |
| ORM1 | orosomucoid 1 | 0.00288875 |
| UPK1B | uroplakin 1B | 0.00288545 |
| MGST2 | microsomal glutathione S-transferase 2 | 0.00288366 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00288029 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00287672 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.00287582 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00286405 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | 0.00286139 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.00286008 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00285942 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00283954 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00283056 |
| OLFM1 | olfactomedin 1 | 0.00281758 |
| TRIM44 | tripartite motif containing 44 | 0.00279477 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00278511 |
| TRIM13 | tripartite motif containing 13 | 0.00278409 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.0027661 |
| TPI1 | triosephosphate isomerase 1 | 0.00275673 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00274556 |
| NOP56 | NOP56 ribonucleoprotein | 0.00274518 |
| HEATR1 | HEAT repeat containing 1 | 0.00274375 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00273752 |
| ATN1 | atrophin 1 | 0.00272788 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00271497 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00270785 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 0.00270584 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00270569 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00270564 |
| PHB2 | prohibitin 2 | 0.0027039 |
| GYS1 | glycogen synthase 1 (muscle) | 0.00270138 |
| TASP1 | taspase, threonine aspartase, 1 | 0.00269959 |
| NREP | neuronal regeneration related protein | 0.00269421 |
| KRT15 | keratin 15, type I | 0.00269334 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0026907 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00268908 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00268857 |
| XIC | X chromosome inactivation center | 0.0026875 |
| LAMA4 | laminin, alpha 4 | 0.00267833 |
| FHL1 | four and a half LIM domains 1 | 0.00267802 |
| MB | myoglobin | 0.00267514 |
| ABI2 | abl-interactor 2 | 0.00267021 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | 0.00266743 |
| EHBP1 | EH domain binding protein 1 | 0.00266226 |
| UBXN7 | UBX domain protein 7 | 0.00265491 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00265411 |
| OCA2 | oculocutaneous albinism II | 0.00265047 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00264656 |
| RAB6B | RAB6B, member RAS oncogene family | 0.00264326 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00264067 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00263129 |
| CD9 | CD9 molecule | 0.00263091 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.00262859 |
| NCK1 | NCK adaptor protein 1 | 0.00262806 |
| NEK7 | NIMA-related kinase 7 | 0.00262638 |
| WIF1 | WNT inhibitory factor 1 | 0.00262382 |
| RPS26 | ribosomal protein S26 | 0.00261662 |
| MEIS1 | Meis homeobox 1 | 0.00261652 |
| KLK11 | kallikrein-related peptidase 11 | 0.00261 |
| FN1 | fibronectin 1 | 0.00260887 |
| CAVIN2 | caveolae associated protein 2 | 0.00260648 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00260583 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00260003 |
| IPO7 | importin 7 | 0.00259892 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00259001 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.00257788 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.00256741 |
| ELANE | elastase, neutrophil expressed | 0.00256207 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0025575 |
| GM2A | GM2 ganglioside activator | 0.00255304 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00255125 |
| IGSF1 | immunoglobulin superfamily, member 1 | 0.0025472 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.00254624 |
| C1ORF95 | chromosome 1 open reading frame 95 | 0.00254526 |
| PDGFC | platelet derived growth factor C | 0.00254478 |
| LOC730101 | uncharacterized LOC730101 | 0.00253964 |
| PLA2G2D | phospholipase A2, group IID | 0.00253812 |
| NFIB | nuclear factor I/B | 0.0025304 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00251999 |
| COG7 | component of oligomeric golgi complex 7 | 0.00251653 |
| FOCAD | focadhesin | 0.00250583 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 0.00250367 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00249885 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00249734 |
| DUSP4 | dual specificity phosphatase 4 | 0.00249637 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00248965 |
| IMMT | inner membrane protein, mitochondrial | 0.00248776 |
| S100B | S100 calcium binding protein B | 0.002482 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00247186 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.0024718 |
| NKX2-1 | NK2 homeobox 1 | 0.00246785 |
| NMB | neuromedin B | 0.00246734 |
| SELL | selectin L | 0.00246687 |
| GPM6A | glycoprotein M6A | 0.00246442 |
| TAOK3 | TAO kinase 3 | 0.00245565 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00245401 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00245395 |
| CSTA | cystatin A (stefin A) | 0.00244373 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00244362 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00243858 |
| WDR7 | WD repeat domain 7 | 0.00243472 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00243345 |
| CTSG | cathepsin G | 0.0024323 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.00242965 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00242844 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.00242709 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00242674 |
| HOMER2 | homer scaffolding protein 2 | 0.00242626 |
| RGS16 | regulator of G-protein signaling 16 | 0.00242115 |
| PMM2 | phosphomannomutase 2 | 0.00241746 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.00241655 |
| CADM1 | cell adhesion molecule 1 | 0.00241318 |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 | 0.00240623 |
| BGN | biglycan | 0.00240622 |
| KIF3B | kinesin family member 3B | 0.00240201 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00240173 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | 0.00239771 |
| RNF7 | ring finger protein 7 | 0.00239376 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00239345 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 | 0.00239197 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00238613 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.00238561 |
| STK10 | serine/threonine kinase 10 | 0.00238488 |
| RAB3B | RAB3B, member RAS oncogene family | 0.00237979 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.010099 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00884645 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0078484 |
| TSPAN8 | tetraspanin 8 | -0.00773086 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00734939 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00686842 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0065575 |
| KRT19 | keratin 19, type I | -0.00633738 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00617232 |
| ASS1 | argininosuccinate synthase 1 | -0.00602751 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.0059042 |
| TFF1 | trefoil factor 1 | -0.005879 |
| PLAU | plasminogen activator, urokinase | -0.00566884 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0055969 |
| EVI2A | ecotropic viral integration site 2A | -0.00549225 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00543922 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0054309 |
| CLGN | calmegin | -0.00542262 |
| HEPH | hephaestin | -0.00535369 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00535227 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00527799 |
| MAP7 | microtubule-associated protein 7 | -0.00520571 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0051979 |
| TPBG | trophoblast glycoprotein | -0.0051258 |
| KRT8 | keratin 8, type II | -0.00511671 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00500814 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00496303 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00493285 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00489025 |
| CLDN7 | claudin 7 | -0.00485598 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00479669 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00479616 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00478715 |
| MMP3 | matrix metallopeptidase 3 | -0.00474226 |
| BLNK | B-cell linker | -0.00473563 |
| MX1 | MX dynamin-like GTPase 1 | -0.00471675 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00470245 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00467301 |
| REG3A | regenerating islet-derived 3 alpha | -0.00465892 |
| CD209 | CD209 molecule | -0.00463946 |
| SIK1 | salt-inducible kinase 1 | -0.00457062 |
| CA2 | carbonic anhydrase II | -0.00455377 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00454666 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00452314 |
| GAS6 | growth arrest-specific 6 | -0.00451359 |
| SPON2 | spondin 2, extracellular matrix protein | -0.0044896 |
| DAXX | death-domain associated protein | -0.00445484 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00445312 |
| SELENBP1 | selenium binding protein 1 | -0.00444762 |
| RCAN1 | regulator of calcineurin 1 | -0.00443977 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00438064 |
| AUTS2 | autism susceptibility candidate 2 | -0.00436454 |
| MCOLN1 | mucolipin 1 | -0.00436249 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.004361 |
| AOC1 | amine oxidase, copper containing 1 | -0.00436068 |
| TPD52 | tumor protein D52 | -0.00434563 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00434194 |
| EGR3 | early growth response 3 | -0.00431226 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00429804 |
| REG1A | regenerating islet-derived 1 alpha | -0.00429592 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00428366 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00427018 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00424599 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00423827 |
| S100P | S100 calcium binding protein P | -0.00421538 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.0041921 |
| GSDMB | gasdermin B | -0.00419021 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00418757 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00418617 |
| CDC20 | cell division cycle 20 | -0.00416912 |
| PLAT | plasminogen activator, tissue | -0.00416096 |
| KRT20 | keratin 20, type I | -0.00414082 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.0041315 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00412101 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0041065 |
| DOCK4 | dedicator of cytokinesis 4 | -0.00410079 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00408091 |
| REG1B | regenerating islet-derived 1 beta | -0.00407392 |
| TUFT1 | tuftelin 1 | -0.00406104 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00398452 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.0039841 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00391121 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00388159 |
| SGCE | sarcoglycan, epsilon | -0.00387915 |
| NVL | nuclear VCP-like | -0.00386528 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00386507 |
| TBC1D12 | TBC1 domain family, member 12 | -0.00385978 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00384156 |
| MYRF | myelin regulatory factor | -0.00383781 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0038164 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00380189 |
| RAI14 | retinoic acid induced 14 | -0.00379694 |
| CLTB | clathrin, light chain B | -0.00378834 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00377137 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00375615 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00375146 |
| TNC | tenascin C | -0.00373127 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00371339 |
| PTK2 | protein tyrosine kinase 2 | -0.0036796 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00366973 |
| AREG | amphiregulin | -0.00365891 |
| PENK | proenkephalin | -0.00365877 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00364438 |
| UFM1 | ubiquitin-fold modifier 1 | -0.00362962 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00362564 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00362211 |
| CDCP1 | CUB domain containing protein 1 | -0.00360361 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00358793 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00357677 |
| FGF13 | fibroblast growth factor 13 | -0.00356184 |
| OLFM4 | olfactomedin 4 | -0.00356091 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -0.00355736 |
| SYNM | synemin, intermediate filament protein | -0.0035491 |
| DACH1 | dachshund family transcription factor 1 | -0.00354871 |
| KIAA0930 | KIAA0930 | -0.00354351 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00353978 |
| CRAT | carnitine O-acetyltransferase | -0.00353123 |
| NPY | neuropeptide Y | -0.00352724 |
| TOX3 | TOX high mobility group box family member 3 | -0.00352596 |
| IL10RA | interleukin 10 receptor, alpha | -0.0035144 |
| KLHL2 | kelch-like family member 2 | -0.00350774 |
| DSE | dermatan sulfate epimerase | -0.00350749 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00350638 |
| PLPP2 | phospholipid phosphatase 2 | -0.0035047 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00350274 |
| CHN2 | chimerin 2 | -0.00349995 |
| CYTIP | cytohesin 1 interacting protein | -0.0034973 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00349662 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00349462 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00348739 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00348526 |
| TOB1 | transducer of ERBB2, 1 | -0.00345045 |
| FA2H | fatty acid 2-hydroxylase | -0.00344906 |
| KLK6 | kallikrein-related peptidase 6 | -0.00344345 |
| HOXC6 | homeobox C6 | -0.00342396 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00342226 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00342203 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0034156 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0034003 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00338682 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00338177 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00337632 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00335972 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00334513 |
| FABP1 | fatty acid binding protein 1, liver | -0.00333714 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00333302 |
| MFAP5 | microfibrillar associated protein 5 | -0.00331852 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00330608 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00330546 |
| CLIC2 | chloride intracellular channel 2 | -0.00330504 |
| RBM47 | RNA binding motif protein 47 | -0.00329954 |
| GUK1 | guanylate kinase 1 | -0.00329926 |
| CANT1 | calcium activated nucleotidase 1 | -0.00329569 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00328055 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.0032738 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | -0.00327272 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00326943 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00325657 |
| CHN1 | chimerin 1 | -0.00321844 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0032148 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00319758 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00319716 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00319502 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -0.00318492 |
| EPCAM | epithelial cell adhesion molecule | -0.00316852 |
| RCAN2 | regulator of calcineurin 2 | -0.0031657 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00315123 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00314829 |
| S100A14 | S100 calcium binding protein A14 | -0.00313199 |
| HBB | hemoglobin, beta | -0.00313076 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00312641 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00311646 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00311407 |
| GATA3 | GATA binding protein 3 | -0.00310847 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00310182 |
| MICB | MHC class I polypeptide-related sequence B | -0.00309584 |
| PLXNC1 | plexin C1 | -0.00309552 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00309379 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00309327 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.00308753 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00308245 |
| TSPAN13 | tetraspanin 13 | -0.00307182 |
| CCL11 | chemokine (C-C motif) ligand 11 | -0.0030717 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00307011 |
| SLAMF7 | SLAM family member 7 | -0.00306899 |
| BLVRB | biliverdin reductase B | -0.0030671 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00305246 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00305089 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00304772 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00303653 |
| GOLGA8A | golgin A8 family, member A | -0.00303428 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00303123 |
| GDF15 | growth differentiation factor 15 | -0.00303063 |
| PRDX2 | peroxiredoxin 2 | -0.00301439 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -0.00301213 |
| ACKR3 | atypical chemokine receptor 3 | -0.00301146 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00300994 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00300117 |
| CLDN4 | claudin 4 | -0.00299652 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | -0.00299233 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00298967 |
| ADAP1 | ArfGAP with dual PH domains 1 | -0.00298299 |
| IL11 | interleukin 11 | -0.00297493 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00297191 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.0029699 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00296369 |
| SDC1 | syndecan 1 | -0.00295641 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | -0.00295553 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00295548 |
| NNMT | nicotinamide N-methyltransferase | -0.00294368 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00293019 |
| RGS2 | regulator of G-protein signaling 2 | -0.00292985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00292292 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00292286 |
| NMU | neuromedin U | -0.00292134 |
| MLF1 | myeloid leukemia factor 1 | -0.00291552 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00291072 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00290744 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00290413 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00289759 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0028967 |
| MMP10 | matrix metallopeptidase 10 | -0.00289536 |
| TGFA | transforming growth factor, alpha | -0.00289159 |
| MYO1D | myosin ID | -0.0028913 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00288271 |
| HIC2 | hypermethylated in cancer 2 | -0.00287736 |
| RND3 | Rho family GTPase 3 | -0.00287476 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00287085 |
| TES | testin LIM domain protein | -0.00286502 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00285557 |
| CLIC5 | chloride intracellular channel 5 | -0.00285328 |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | -0.00285165 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00285094 |
| NRBF2 | nuclear receptor binding factor 2 | -0.00284891 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00284342 |
| PRSS8 | protease, serine, 8 | -0.00284082 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00283331 |
| ANXA4 | annexin A4 | -0.00282908 |
| KIF13B | kinesin family member 13B | -0.00282083 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00282072 |
| PHF1 | PHD finger protein 1 | -0.00281851 |
| BMP2 | bone morphogenetic protein 2 | -0.00281646 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00281075 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.002809 |
| TBX3 | T-box 3 | -0.00280344 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00280273 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00279895 |
| NAV3 | neuron navigator 3 | -0.00279694 |
| ZNF395 | zinc finger protein 395 | -0.00279465 |