ABL1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ABL proto-oncogene 1, non-receptor tyrosine kinase|This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014] (NCBI Entrez Gene Database, 25)
External Link https://ncbi.nlm.nih.gov/gene/25
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Genes

499 genes differentially expressed following the ABL1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00733851
BEX1 brain expressed, X-linked 1 0.00712143
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00664868
FABP7 fatty acid binding protein 7, brain 0.00661142
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00595733
SFTPB surfactant protein B 0.00573221
FGG fibrinogen gamma chain 0.00533226
HOPX HOP homeobox 0.00508015
A2M alpha-2-macroglobulin 0.00499898
MPO myeloperoxidase 0.00498546
ASCL1 achaete-scute family bHLH transcription factor 1 0.00486019
SFTPD surfactant protein D 0.00485396
FGA fibrinogen alpha chain 0.0048423
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00474926
SFTPA2 surfactant protein A2 0.00468061
POSTN periostin, osteoblast specific factor 0.00464899
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00458839
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00456604
TNS3 tensin 3 0.00447699
RFTN1 raftlin, lipid raft linker 1 0.00443521
APOD apolipoprotein D 0.00439114
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00434917
HSPB1 heat shock 27kDa protein 1 0.00425645
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00422202
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00421162
PODXL podocalyxin-like 0.00420006
MGP matrix Gla protein 0.00408969
KRT6A keratin 6A, type II 0.00403802
ADGRE1 adhesion G protein-coupled receptor E1 0.00402299
DMD dystrophin 0.00400967
KANK1 KN motif and ankyrin repeat domains 1 0.00399264
PDE8B phosphodiesterase 8B 0.00398772
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00396519
EHD3 EH-domain containing 3 0.00392856
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00392455
H2AFV H2A histone family, member V 0.00391626
MAL mal, T-cell differentiation protein 0.00390743
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00389062
TCTA T-cell leukemia translocation altered 0.00386903
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00385436
LTA4H leukotriene A4 hydrolase 0.00381028
PCNA proliferating cell nuclear antigen 0.00380093
SNX5 sorting nexin 5 0.00379293
GJA1 gap junction protein, alpha 1, 43kDa 0.00372331
KRT14 keratin 14, type I 0.00371866
DUOX1 dual oxidase 1 0.00368822
SFTPC surfactant protein C 0.00367346
CD200 CD200 molecule 0.00366807
MFGE8 milk fat globule-EGF factor 8 protein 0.00366287
CHD9 chromodomain helicase DNA binding protein 9 0.00365376
TIMP4 TIMP metallopeptidase inhibitor 4 0.00360563
TIMP3 TIMP metallopeptidase inhibitor 3 0.00360213
GSTA4 glutathione S-transferase alpha 4 0.00359052
ZMAT3 zinc finger, matrin-type 3 0.00358074
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00355373
MAMLD1 mastermind-like domain containing 1 0.00355072
GPI glucose-6-phosphate isomerase 0.00353265
CES1 carboxylesterase 1 0.00351932
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00348975
COG2 component of oligomeric golgi complex 2 0.00348477
OXA1L oxidase (cytochrome c) assembly 1-like 0.00348026
KRT13 keratin 13, type I 0.00347455
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00344098
CXADR coxsackie virus and adenovirus receptor 0.00343539
APOC1 apolipoprotein C-I 0.00343501
DPP8 dipeptidyl-peptidase 8 0.00341663
CD93 CD93 molecule 0.00341603
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00341223
TMCC1 transmembrane and coiled-coil domain family 1 0.0034058
GSTP1 glutathione S-transferase pi 1 0.00333757
F3 coagulation factor III (thromboplastin, tissue factor) 0.00332271
CHRDL1 chordin-like 1 0.00331552
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.00329815
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00328533
RRBP1 ribosome binding protein 1 0.00327397
ZNF185 zinc finger protein 185 (LIM domain) 0.00326502
CRYAB crystallin, alpha B 0.00324711
PTPRM protein tyrosine phosphatase, receptor type, M 0.00323747
SOX10 SRY (sex determining region Y)-box 10 0.00322896
FOLR1 folate receptor 1 (adult) 0.0032279
SNX11 sorting nexin 11 0.0032138
RAPSN receptor-associated protein of the synapse 0.00320866
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00320797
RGS5 regulator of G-protein signaling 5 0.00320748
GAB2 GRB2-associated binding protein 2 0.00320269
MYH10 myosin, heavy chain 10, non-muscle 0.00319738
GNAS GNAS complex locus 0.0031969
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00318792
SOCS2 suppressor of cytokine signaling 2 0.00318723
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.0031869
CS citrate synthase 0.00318584
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00318542
NOTCH2 notch 2 0.00314551
KRT5 keratin 5, type II 0.00313628
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0031341
TALDO1 transaldolase 1 0.00312356
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.0030996
DERA deoxyribose-phosphate aldolase (putative) 0.00309928
SCD5 stearoyl-CoA desaturase 5 0.00309397
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00309155
PGC progastricsin (pepsinogen C) 0.0030858
PLA1A phospholipase A1 member A 0.0030558
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00304319
EDNRB endothelin receptor type B 0.00303665
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00303449
TNNC1 troponin C type 1 (slow) 0.00302055
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00300649
TACSTD2 tumor-associated calcium signal transducer 2 0.00300213
NDRG4 NDRG family member 4 0.00299331
ETV5 ets variant 5 0.00297715
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00297576
KPNB1 karyopherin (importin) beta 1 0.00297321
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00297298
PRAME preferentially expressed antigen in melanoma 0.00297046
GRB14 growth factor receptor-bound protein 14 0.00297005
OXTR oxytocin receptor 0.00296457
DNTT DNA nucleotidylexotransferase 0.00295488
SEC23B Sec23 homolog B (S. cerevisiae) 0.00295363
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00295197
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.00294686
TGM2 transglutaminase 2 0.00293844
EGFL6 EGF-like-domain, multiple 6 0.00293364
IL1RAP interleukin 1 receptor accessory protein 0.00291958
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0029145
PDHX pyruvate dehydrogenase complex, component X 0.00290844
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00290297
HP haptoglobin 0.00289829
ORM1 orosomucoid 1 0.00288875
UPK1B uroplakin 1B 0.00288545
MGST2 microsomal glutathione S-transferase 2 0.00288366
GTF2H5 general transcription factor IIH, polypeptide 5 0.00288029
LRP4 low density lipoprotein receptor-related protein 4 0.00287672
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.00287582
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.00286405
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00286139
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.00286008
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.00285942
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00283954
MPPED2 metallophosphoesterase domain containing 2 0.00283056
OLFM1 olfactomedin 1 0.00281758
TRIM44 tripartite motif containing 44 0.00279477
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.00278511
TRIM13 tripartite motif containing 13 0.00278409
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.0027661
TPI1 triosephosphate isomerase 1 0.00275673
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.00274556
NOP56 NOP56 ribonucleoprotein 0.00274518
HEATR1 HEAT repeat containing 1 0.00274375
BPIFA1 BPI fold containing family A, member 1 0.00273752
ATN1 atrophin 1 0.00272788
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00271497
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00270785
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.00270584
ADGRF5 adhesion G protein-coupled receptor F5 0.00270569
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00270564
PHB2 prohibitin 2 0.0027039
GYS1 glycogen synthase 1 (muscle) 0.00270138
TASP1 taspase, threonine aspartase, 1 0.00269959
NREP neuronal regeneration related protein 0.00269421
KRT15 keratin 15, type I 0.00269334
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0026907
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00268908
DYNLL1 dynein, light chain, LC8-type 1 0.00268857
XIC X chromosome inactivation center 0.0026875
LAMA4 laminin, alpha 4 0.00267833
FHL1 four and a half LIM domains 1 0.00267802
MB myoglobin 0.00267514
ABI2 abl-interactor 2 0.00267021
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.00266743
EHBP1 EH domain binding protein 1 0.00266226
UBXN7 UBX domain protein 7 0.00265491
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00265411
OCA2 oculocutaneous albinism II 0.00265047
COL9A3 collagen, type IX, alpha 3 0.00264656
RAB6B RAB6B, member RAS oncogene family 0.00264326
PHACTR2 phosphatase and actin regulator 2 0.00264067
SLPI secretory leukocyte peptidase inhibitor 0.00263129
CD9 CD9 molecule 0.00263091
PCYOX1 prenylcysteine oxidase 1 0.00262859
NCK1 NCK adaptor protein 1 0.00262806
NEK7 NIMA-related kinase 7 0.00262638
WIF1 WNT inhibitory factor 1 0.00262382
RPS26 ribosomal protein S26 0.00261662
MEIS1 Meis homeobox 1 0.00261652
KLK11 kallikrein-related peptidase 11 0.00261
FN1 fibronectin 1 0.00260887
CAVIN2 caveolae associated protein 2 0.00260648
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00260583
AHCYL1 adenosylhomocysteinase-like 1 0.00260003
IPO7 importin 7 0.00259892
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00259001
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.00257788
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.00256741
ELANE elastase, neutrophil expressed 0.00256207
NT5C2 5'-nucleotidase, cytosolic II 0.0025575
GM2A GM2 ganglioside activator 0.00255304
RNASE3 ribonuclease, RNase A family, 3 0.00255125
IGSF1 immunoglobulin superfamily, member 1 0.0025472
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.00254624
C1ORF95 chromosome 1 open reading frame 95 0.00254526
PDGFC platelet derived growth factor C 0.00254478
LOC730101 uncharacterized LOC730101 0.00253964
PLA2G2D phospholipase A2, group IID 0.00253812
NFIB nuclear factor I/B 0.0025304
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00251999
COG7 component of oligomeric golgi complex 7 0.00251653
FOCAD focadhesin 0.00250583
DET1 de-etiolated homolog 1 (Arabidopsis) 0.00250367
IGSF3 immunoglobulin superfamily, member 3 0.00249885
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00249734
DUSP4 dual specificity phosphatase 4 0.00249637
EPAS1 endothelial PAS domain protein 1 0.00248965
IMMT inner membrane protein, mitochondrial 0.00248776
S100B S100 calcium binding protein B 0.002482
LPP LIM domain containing preferred translocation partner in lipoma 0.00247186
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.0024718
NKX2-1 NK2 homeobox 1 0.00246785
NMB neuromedin B 0.00246734
SELL selectin L 0.00246687
GPM6A glycoprotein M6A 0.00246442
TAOK3 TAO kinase 3 0.00245565
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00245401
VAMP5 vesicle-associated membrane protein 5 0.00245395
CSTA cystatin A (stefin A) 0.00244373
SV2A synaptic vesicle glycoprotein 2A 0.00244362
PRSS21 protease, serine, 21 (testisin) 0.00243858
WDR7 WD repeat domain 7 0.00243472
RSL1D1 ribosomal L1 domain containing 1 0.00243345
CTSG cathepsin G 0.0024323
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.00242965
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.00242844
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.00242709
FRS2 fibroblast growth factor receptor substrate 2 0.00242674
HOMER2 homer scaffolding protein 2 0.00242626
RGS16 regulator of G-protein signaling 16 0.00242115
PMM2 phosphomannomutase 2 0.00241746
AHCYL2 adenosylhomocysteinase-like 2 0.00241655
CADM1 cell adhesion molecule 1 0.00241318
PPP1R17 protein phosphatase 1, regulatory subunit 17 0.00240623
BGN biglycan 0.00240622
KIF3B kinesin family member 3B 0.00240201
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00240173
MAP3K6 mitogen-activated protein kinase kinase kinase 6 0.00239771
RNF7 ring finger protein 7 0.00239376
PNMA2 paraneoplastic Ma antigen 2 0.00239345
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.00239197
RUFY3 RUN and FYVE domain containing 3 0.00238613
ZMYND11 zinc finger, MYND-type containing 11 0.00238561
STK10 serine/threonine kinase 10 0.00238488
RAB3B RAB3B, member RAS oncogene family 0.00237979

decreased expression

Symbol Name Standardized Value
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.010099
GRB7 growth factor receptor-bound protein 7 -0.00884645
GREM1 gremlin 1, DAN family BMP antagonist -0.0078484
TSPAN8 tetraspanin 8 -0.00773086
MDK midkine (neurite growth-promoting factor 2) -0.00734939
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00686842
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0065575
KRT19 keratin 19, type I -0.00633738
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00617232
ASS1 argininosuccinate synthase 1 -0.00602751
ALDOB aldolase B, fructose-bisphosphate -0.0059042
TFF1 trefoil factor 1 -0.005879
PLAU plasminogen activator, urokinase -0.00566884
ANPEP alanyl (membrane) aminopeptidase -0.0055969
EVI2A ecotropic viral integration site 2A -0.00549225
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00543922
SLC38A1 solute carrier family 38, member 1 -0.0054309
CLGN calmegin -0.00542262
HEPH hephaestin -0.00535369
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00535227
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00527799
MAP7 microtubule-associated protein 7 -0.00520571
TGFBI transforming growth factor, beta-induced, 68kDa -0.0051979
TPBG trophoblast glycoprotein -0.0051258
KRT8 keratin 8, type II -0.00511671
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00500814
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00496303
LPAR1 lysophosphatidic acid receptor 1 -0.00493285
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00489025
CLDN7 claudin 7 -0.00485598
COL6A2 collagen, type VI, alpha 2 -0.00479669
TUBB2A tubulin, beta 2A class IIa -0.00479616
RAB40B RAB40B, member RAS oncogene family -0.00478715
MMP3 matrix metallopeptidase 3 -0.00474226
BLNK B-cell linker -0.00473563
MX1 MX dynamin-like GTPase 1 -0.00471675
SFRP1 secreted frizzled-related protein 1 -0.00470245
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00467301
REG3A regenerating islet-derived 3 alpha -0.00465892
CD209 CD209 molecule -0.00463946
SIK1 salt-inducible kinase 1 -0.00457062
CA2 carbonic anhydrase II -0.00455377
NT5E 5'-nucleotidase, ecto (CD73) -0.00454666
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00452314
GAS6 growth arrest-specific 6 -0.00451359
SPON2 spondin 2, extracellular matrix protein -0.0044896
DAXX death-domain associated protein -0.00445484
EIF5A eukaryotic translation initiation factor 5A -0.00445312
SELENBP1 selenium binding protein 1 -0.00444762
RCAN1 regulator of calcineurin 1 -0.00443977
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00438064
AUTS2 autism susceptibility candidate 2 -0.00436454
MCOLN1 mucolipin 1 -0.00436249
IFI6 interferon, alpha-inducible protein 6 -0.004361
AOC1 amine oxidase, copper containing 1 -0.00436068
TPD52 tumor protein D52 -0.00434563
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00434194
EGR3 early growth response 3 -0.00431226
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00429804
REG1A regenerating islet-derived 1 alpha -0.00429592
MKNK1 MAP kinase interacting serine/threonine kinase 1 -0.00428366
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00427018
PDLIM4 PDZ and LIM domain 4 -0.00424599
PDZK1IP1 PDZK1 interacting protein 1 -0.00423827
S100P S100 calcium binding protein P -0.00421538
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.0041921
GSDMB gasdermin B -0.00419021
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00418757
SI sucrase-isomaltase (alpha-glucosidase) -0.00418617
CDC20 cell division cycle 20 -0.00416912
PLAT plasminogen activator, tissue -0.00416096
KRT20 keratin 20, type I -0.00414082
CXCL6 chemokine (C-X-C motif) ligand 6 -0.0041315
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.00412101
TFF3 trefoil factor 3 (intestinal) -0.0041065
DOCK4 dedicator of cytokinesis 4 -0.00410079
SCGB2A2 secretoglobin, family 2A, member 2 -0.00408091
REG1B regenerating islet-derived 1 beta -0.00407392
TUFT1 tuftelin 1 -0.00406104
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00398452
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.0039841
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00391121
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00388159
SGCE sarcoglycan, epsilon -0.00387915
NVL nuclear VCP-like -0.00386528
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00386507
TBC1D12 TBC1 domain family, member 12 -0.00385978
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00384156
MYRF myelin regulatory factor -0.00383781
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0038164
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00380189
RAI14 retinoic acid induced 14 -0.00379694
CLTB clathrin, light chain B -0.00378834
COL14A1 collagen, type XIV, alpha 1 -0.00377137
GPNMB glycoprotein (transmembrane) nmb -0.00375615
TST thiosulfate sulfurtransferase (rhodanese) -0.00375146
TNC tenascin C -0.00373127
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00371339
PTK2 protein tyrosine kinase 2 -0.0036796
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00366973
AREG amphiregulin -0.00365891
PENK proenkephalin -0.00365877
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00364438
UFM1 ubiquitin-fold modifier 1 -0.00362962
KLF4 Kruppel-like factor 4 (gut) -0.00362564
QPCT glutaminyl-peptide cyclotransferase -0.00362211
CDCP1 CUB domain containing protein 1 -0.00360361
BASP1 brain abundant, membrane attached signal protein 1 -0.00358793
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00357677
FGF13 fibroblast growth factor 13 -0.00356184
OLFM4 olfactomedin 4 -0.00356091
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00355736
SYNM synemin, intermediate filament protein -0.0035491
DACH1 dachshund family transcription factor 1 -0.00354871
KIAA0930 KIAA0930 -0.00354351
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00353978
CRAT carnitine O-acetyltransferase -0.00353123
NPY neuropeptide Y -0.00352724
TOX3 TOX high mobility group box family member 3 -0.00352596
IL10RA interleukin 10 receptor, alpha -0.0035144
KLHL2 kelch-like family member 2 -0.00350774
DSE dermatan sulfate epimerase -0.00350749
MAB21L2 mab-21-like 2 (C. elegans) -0.00350638
PLPP2 phospholipid phosphatase 2 -0.0035047
SSBP2 single-stranded DNA binding protein 2 -0.00350274
CHN2 chimerin 2 -0.00349995
CYTIP cytohesin 1 interacting protein -0.0034973
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00349662
TMPRSS4 transmembrane protease, serine 4 -0.00349462
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00348739
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00348526
TOB1 transducer of ERBB2, 1 -0.00345045
FA2H fatty acid 2-hydroxylase -0.00344906
KLK6 kallikrein-related peptidase 6 -0.00344345
HOXC6 homeobox C6 -0.00342396
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00342226
SOX9 SRY (sex determining region Y)-box 9 -0.00342203
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0034156
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.0034003
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00338682
PDGFRL platelet-derived growth factor receptor-like -0.00338177
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00337632
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00335972
HSPA2 heat shock 70kDa protein 2 -0.00334513
FABP1 fatty acid binding protein 1, liver -0.00333714
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00333302
MFAP5 microfibrillar associated protein 5 -0.00331852
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00330608
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00330546
CLIC2 chloride intracellular channel 2 -0.00330504
RBM47 RNA binding motif protein 47 -0.00329954
GUK1 guanylate kinase 1 -0.00329926
CANT1 calcium activated nucleotidase 1 -0.00329569
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00328055
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.0032738
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00327272
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00326943
IL13RA2 interleukin 13 receptor, alpha 2 -0.00325657
CHN1 chimerin 1 -0.00321844
GLIPR1 GLI pathogenesis-related 1 -0.0032148
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00319758
JCHAIN joining chain of multimeric IgA and IgM -0.00319716
VCAM1 vascular cell adhesion molecule 1 -0.00319502
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -0.00318492
EPCAM epithelial cell adhesion molecule -0.00316852
RCAN2 regulator of calcineurin 2 -0.0031657
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00315123
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00314829
S100A14 S100 calcium binding protein A14 -0.00313199
HBB hemoglobin, beta -0.00313076
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00312641
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00311646
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -0.00311407
GATA3 GATA binding protein 3 -0.00310847
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00310182
MICB MHC class I polypeptide-related sequence B -0.00309584
PLXNC1 plexin C1 -0.00309552
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00309379
OSR2 odd-skipped related transciption factor 2 -0.00309327
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00308753
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00308245
TSPAN13 tetraspanin 13 -0.00307182
CCL11 chemokine (C-C motif) ligand 11 -0.0030717
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00307011
SLAMF7 SLAM family member 7 -0.00306899
BLVRB biliverdin reductase B -0.0030671
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00305246
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00305089
CCL8 chemokine (C-C motif) ligand 8 -0.00304772
PUF60 poly-U binding splicing factor 60KDa -0.00303653
GOLGA8A golgin A8 family, member A -0.00303428
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00303123
GDF15 growth differentiation factor 15 -0.00303063
PRDX2 peroxiredoxin 2 -0.00301439
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00301213
ACKR3 atypical chemokine receptor 3 -0.00301146
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00300994
SGK1 serum/glucocorticoid regulated kinase 1 -0.00300117
CLDN4 claudin 4 -0.00299652
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -0.00299233
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00298967
ADAP1 ArfGAP with dual PH domains 1 -0.00298299
IL11 interleukin 11 -0.00297493
FGFR2 fibroblast growth factor receptor 2 -0.00297191
PDE2A phosphodiesterase 2A, cGMP-stimulated -0.0029699
KCTD5 potassium channel tetramerization domain containing 5 -0.00296369
SDC1 syndecan 1 -0.00295641
STARD3 StAR-related lipid transfer (START) domain containing 3 -0.00295553
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00295548
NNMT nicotinamide N-methyltransferase -0.00294368
PRUNE2 prune homolog 2 (Drosophila) -0.00293019
RGS2 regulator of G-protein signaling 2 -0.00292985
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00292292
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00292286
NMU neuromedin U -0.00292134
MLF1 myeloid leukemia factor 1 -0.00291552
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00291072
CYBA cytochrome b-245, alpha polypeptide -0.00290744
NUSAP1 nucleolar and spindle associated protein 1 -0.00290413
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00289759
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0028967
MMP10 matrix metallopeptidase 10 -0.00289536
TGFA transforming growth factor, alpha -0.00289159
MYO1D myosin ID -0.0028913
CLEC3B C-type lectin domain family 3, member B -0.00288271
HIC2 hypermethylated in cancer 2 -0.00287736
RND3 Rho family GTPase 3 -0.00287476
PI3 peptidase inhibitor 3, skin-derived -0.00287085
TES testin LIM domain protein -0.00286502
GEM GTP binding protein overexpressed in skeletal muscle -0.00285557
CLIC5 chloride intracellular channel 5 -0.00285328
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound -0.00285165
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00285094
NRBF2 nuclear receptor binding factor 2 -0.00284891
LAT2 linker for activation of T cells family, member 2 -0.00284342
PRSS8 protease, serine, 8 -0.00284082
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00283331
ANXA4 annexin A4 -0.00282908
KIF13B kinesin family member 13B -0.00282083
ECI2 enoyl-CoA delta isomerase 2 -0.00282072
PHF1 PHD finger protein 1 -0.00281851
BMP2 bone morphogenetic protein 2 -0.00281646
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00281075
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.002809
TBX3 T-box 3 -0.00280344
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00280273
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00279895
NAV3 neuron navigator 3 -0.00279694
ZNF395 zinc finger protein 395 -0.00279465