ABL1_mutant_179_GSE45452 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE45452
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Genes

600 genes differentially expressed following the ABL1_mutant_179_GSE45452 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
RAB3IP RAB3A interacting protein 3.56413
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 3.48229
MRPL22 mitochondrial ribosomal protein L22 3.43076
CA2 carbonic anhydrase II 3.39394
MRPL35 mitochondrial ribosomal protein L35 3.17937
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 3.1269
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 3.05991
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 3.0264
RHBDD1 rhomboid domain containing 1 3.02362
BRWD1 bromodomain and WD repeat domain containing 1 2.97563
HPS1 Hermansky-Pudlak syndrome 1 2.95176
COPS8 COP9 signalosome subunit 8 2.94948
MSI2 musashi RNA-binding protein 2 2.94315
DIAPH3 diaphanous-related formin 3 2.83237
DOCK9 dedicator of cytokinesis 9 2.83174
PRR5 proline rich 5 (renal) 2.81777
LEPR leptin receptor 2.8073
CELF1 CUGBP, Elav-like family member 1 2.76183
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 2.75843
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 2.66453
CPZ carboxypeptidase Z 2.65671
FOXJ3 forkhead box J3 2.64255
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.59905
CR2 complement component (3d/Epstein Barr virus) receptor 2 2.59416
TMEM233 transmembrane protein 233 2.58681
TPM1 tropomyosin 1 (alpha) 2.58458
ICE2 interactor of little elongation complex ELL subunit 2 2.58362
REXO2 RNA exonuclease 2 2.58159
C2ORF49 chromosome 2 open reading frame 49 2.56913
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.55458
TPX2 TPX2, microtubule-associated 2.5533
CKAP5 cytoskeleton associated protein 5 2.54444
CYB5A cytochrome b5 type A (microsomal) 2.5424
CSNK1E casein kinase 1, epsilon 2.52276
CDCA8 cell division cycle associated 8 2.51728
ERBB2IP erbb2 interacting protein 2.51554
ODF2 outer dense fiber of sperm tails 2 2.50834
TTK TTK protein kinase 2.4818
PDRG1 p53 and DNA-damage regulated 1 2.48111
NOL6 nucleolar protein 6 (RNA-associated) 2.45067
CKS1B CDC28 protein kinase regulatory subunit 1B 2.4486
PHF6 PHD finger protein 6 2.44619
UBE2M ubiquitin-conjugating enzyme E2M 2.44052
PTTG3P pituitary tumor-transforming 3, pseudogene 2.39664
INO80 INO80 complex subunit 2.39656
FAM131A family with sequence similarity 131, member A 2.39392
MTX2 metaxin 2 2.38029
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 2.37713
SNORA18 small nucleolar RNA, H/ACA box 18 2.37167
LPIN2 lipin 2 2.34895
RPL17 ribosomal protein L17 2.32681
MAP2K4 mitogen-activated protein kinase kinase 4 2.32181
CSNK2A1 casein kinase 2, alpha 1 polypeptide 2.32138
KRIT1 KRIT1, ankyrin repeat containing 2.30467
DHRS11 dehydrogenase/reductase (SDR family) member 11 2.29122
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 2.28011
CCNB2 cyclin B2 2.27989
CSNK1A1 casein kinase 1, alpha 1 2.26627
SLC25A38 solute carrier family 25, member 38 2.24156
RDM1 RAD52 motif containing 1 2.21148
ATN1 atrophin 1 2.20278
PIEZO2 piezo-type mechanosensitive ion channel component 2 2.17625
SNORD68 small nucleolar RNA, C/D box 68 2.16403
ANAPC10 anaphase promoting complex subunit 10 2.16145
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.15108
TRIP13 thyroid hormone receptor interactor 13 2.15088
SORBS1 sorbin and SH3 domain containing 1 2.14173
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 2.14102
MGARP mitochondria-localized glutamic acid-rich protein 2.14102
EIF4E2 eukaryotic translation initiation factor 4E family member 2 2.13207
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 2.1228
ASCC3 activating signal cointegrator 1 complex subunit 3 2.12193
S100A6 S100 calcium binding protein A6 2.11991
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 2.11624
PLK1 polo-like kinase 1 2.11435
STEAP3 STEAP family member 3, metalloreductase 2.11408
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 2.10538
SNORA80A small nucleolar RNA, H/ACA box 80A 2.10351
FDX1L ferredoxin 1-like 2.10344
C8ORF33 chromosome 8 open reading frame 33 2.10303
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2.09931
LTN1 listerin E3 ubiquitin protein ligase 1 2.09797
ACOT7 acyl-CoA thioesterase 7 2.09672
XK X-linked Kx blood group 2.0956
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.0891
SGPP1 sphingosine-1-phosphate phosphatase 1 2.08664
GTPBP8 GTP-binding protein 8 (putative) 2.08486
NCS1 neuronal calcium sensor 1 2.07652
NUP88 nucleoporin 88kDa 2.07611
LINC00152 long intergenic non-protein coding RNA 152 2.07429
MAN2A1 mannosidase, alpha, class 2A, member 1 2.06004
PKLR pyruvate kinase, liver and RBC 2.0517
AP2B1 adaptor-related protein complex 2, beta 1 subunit 2.04704
KEAP1 kelch-like ECH-associated protein 1 2.04388
FBXO7 F-box protein 7 2.0407
BOLA3 bolA family member 3 2.03901
SNORD46 small nucleolar RNA, C/D box 46 2.03733
NARF nuclear prelamin A recognition factor 2.02781
POC1A POC1 centriolar protein A 2.02259
TUBG1 tubulin, gamma 1 2.02001
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 2.01982
VPS9D1-AS1 VPS9D1 antisense RNA 1 2.01877
XPO7 exportin 7 2.00651
PIBF1 progesterone immunomodulatory binding factor 1 2.0043
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.00403
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.00331
CTTN cortactin 2.00168
UBAC1 UBA domain containing 1 1.99216
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.98585
ANKRD9 ankyrin repeat domain 9 1.97994
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.97994
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.97731
OSBP2 oxysterol binding protein 2 1.97621
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.97117
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.96721
COL6A5 collagen, type VI, alpha 5 1.96546
HLTF helicase-like transcription factor 1.96371
RACGAP1 Rac GTPase activating protein 1 1.96213
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 1.95506
CBX3 chromobox homolog 3 1.9473
PWP1 PWP1 homolog (S. cerevisiae) 1.94474
MATR3 matrin 3 1.94416
FAM72B family with sequence similarity 72, member B 1.94129
CAB39L calcium binding protein 39-like 1.94124
SHISA5 shisa family member 5 1.94097
ANKRD16 ankyrin repeat domain 16 1.93956
TFRC transferrin receptor 1.93865
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 1.92734
SGOL1 shugoshin-like 1 (S. pombe) 1.92279
BMP2K BMP2 inducible kinase 1.91984
KIF20A kinesin family member 20A 1.91868
MRPL4 mitochondrial ribosomal protein L4 1.91396
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.91378
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.91359
CDK1 cyclin-dependent kinase 1 1.91127
CPOX coproporphyrinogen oxidase 1.90235
JADE1 jade family PHD finger 1 1.89496
USP6NL USP6 N-terminal like 1.88559
BTF3 basic transcription factor 3 1.87786
WT1 Wilms tumor 1 1.87621
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 1.8643
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 1.86018
TRIM37 tripartite motif containing 37 1.85556
FAM83A family with sequence similarity 83, member A 1.85526
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.85478
ECD ecdysoneless homolog (Drosophila) 1.85306
RMDN3 regulator of microtubule dynamics 3 1.85123
OAT ornithine aminotransferase 1.85122
GOLGA2P7 golgin A2 pseudogene 7 1.83667
SYBU syntabulin (syntaxin-interacting) 1.82669
USP48 ubiquitin specific peptidase 48 1.82496
DNAAF5 dynein, axonemal, assembly factor 5 1.82116
CHPF chondroitin polymerizing factor 1.8186
RCL1 RNA terminal phosphate cyclase-like 1 1.81008
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 1.80912
SETD8 SET domain containing (lysine methyltransferase) 8 1.80541
ACSL3 acyl-CoA synthetase long-chain family member 3 1.80234
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.80094
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.7994
EFTUD1 elongation factor Tu GTP binding domain containing 1 1.79575
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene 1.79528
DEPDC1 DEP domain containing 1 1.79493
NUSAP1 nucleolar and spindle associated protein 1 1.78587
TRIM58 tripartite motif containing 58 1.78525
GABPB1 GA binding protein transcription factor, beta subunit 1 1.7843
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 1.78359
INCENP inner centromere protein antigens 135/155kDa 1.7822
DCK deoxycytidine kinase 1.77914
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.77768
U2SURP U2 snRNP-associated SURP domain containing 1.77482
DLD dihydrolipoamide dehydrogenase 1.77337
CDCA3 cell division cycle associated 3 1.77048
TSTA3 tissue specific transplantation antigen P35B 1.76042
STOML2 stomatin (EPB72)-like 2 1.76002
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 1.75654
PKP4 plakophilin 4 1.75443
TBRG4 transforming growth factor beta regulator 4 1.75061
MYL4 myosin, light chain 4, alkali; atrial, embryonic 1.7497
RANBP10 RAN binding protein 10 1.74771
TSKU tsukushi, small leucine rich proteoglycan 1.7468
RPP21 ribonuclease P/MRP 21kDa subunit 1.74538
THOC7 THO complex 7 1.74134
PROS1 protein S (alpha) 1.74093
CCDC34 coiled-coil domain containing 34 1.74074
CYC1 cytochrome c-1 1.73807
CCDC59 coiled-coil domain containing 59 1.73442
BCAP29 B-cell receptor-associated protein 29 1.73436
CACYBP calcyclin binding protein 1.73247
DIABLO diablo, IAP-binding mitochondrial protein 1.7182
SNORA11B small nucleolar RNA, H/ACA box 11B 1.71742
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.71621
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.71501
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.71173
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 1.70891
TBC1D32 TBC1 domain family, member 32 1.7046
FAM83D family with sequence similarity 83, member D 1.70355
PCCB propionyl CoA carboxylase, beta polypeptide 1.70346
GCDH glutaryl-CoA dehydrogenase 1.70229
CAPRIN1 cell cycle associated protein 1 1.69851
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.69714
SPTB spectrin, beta, erythrocytic 1.6965
TFG TRK-fused gene 1.69625
DEPDC1B DEP domain containing 1B 1.69549
YME1L1 YME1-like 1 ATPase 1.69305
ATXN2L ataxin 2-like 1.68935
FAM210B family with sequence similarity 210, member B 1.68843
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 1.68653
LAGE3 L antigen family, member 3 1.68354
TMEM14C transmembrane protein 14C 1.68272
LBH limb bud and heart development 1.68166
TMEM108 transmembrane protein 108 1.68151
UBQLN1 ubiquilin 1 1.68043
EMC3 ER membrane protein complex subunit 3 1.6767
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 1.67391
SEC14L1 SEC14-like 1 (S. cerevisiae) 1.67378
C6ORF106 chromosome 6 open reading frame 106 1.66924
ACO1 aconitase 1, soluble 1.66852
GPX3 glutathione peroxidase 3 1.66778
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.66577
ZNF451 zinc finger protein 451 1.66364
DAP3 death associated protein 3 1.66247
RBM43 RNA binding motif protein 43 1.66039
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 1.65761
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.65571
GSR glutathione reductase 1.65218
GAB1 GRB2-associated binding protein 1 1.6483
OSGIN2 oxidative stress induced growth inhibitor family member 2 1.64638
RPS21 ribosomal protein S21 1.64619
HBQ1 hemoglobin, theta 1 1.64583
MRPL32 mitochondrial ribosomal protein L32 1.6458
CHMP5 charged multivesicular body protein 5 1.64282
LRRC42 leucine rich repeat containing 42 1.64157
BAG3 BCL2-associated athanogene 3 1.64119
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.64061
ORC5 origin recognition complex, subunit 5 1.63981
RIOK3 RIO kinase 3 1.63622
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 1.63325
OTUD6B OTU domain containing 6B 1.63268
REPS2 RALBP1 associated Eps domain containing 2 1.63117
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.62789
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 1.62511
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.62424
NUPL1 nucleoporin like 1 1.62186
BTNL3 butyrophilin-like 3 1.62021
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.61838
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 1.61533
RIF1 replication timing regulatory factor 1 1.61331
ANKRD20A1 ankyrin repeat domain 20 family, member A1 1.61064
COX17 COX17 cytochrome c oxidase copper chaperone 1.60664
VAMP4 vesicle-associated membrane protein 4 1.60374
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.60329
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 1.60286
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.60257
NUP35 nucleoporin 35kDa 1.60176
CDC25C cell division cycle 25C 1.59421
NUP37 nucleoporin 37kDa 1.59401
AK4 adenylate kinase 4 1.5913
TWSG1 twisted gastrulation BMP signaling modulator 1 1.59017
C9ORF64 chromosome 9 open reading frame 64 1.58799
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 1.58446
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.58417
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.58328
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.58145
CREB1 cAMP responsive element binding protein 1 1.58143
XPO4 exportin 4 1.58123
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 1.57681
MAPK6 mitogen-activated protein kinase 6 1.57619
MRPS30 mitochondrial ribosomal protein S30 1.57614
TUBB tubulin, beta class I 1.57302
PCNP PEST proteolytic signal containing nuclear protein 1.57065
DPH6 diphthamine biosynthesis 6 1.56945
COX5A cytochrome c oxidase subunit Va 1.56918
ARL4A ADP-ribosylation factor-like 4A 1.56906
ABHD2 abhydrolase domain containing 2 1.56639
TBPL1 TBP-like 1 1.56598
RAB2B RAB2B, member RAS oncogene family 1.56494
CLUAP1 clusterin associated protein 1 1.56319
KIF15 kinesin family member 15 1.56308
NACAD NAC alpha domain containing 1.56255
MOB4 MOB family member 4, phocein 1.56111
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.56014
MED1 mediator complex subunit 1 1.55853
SDE2 SDE2 telomere maintenance homolog (S. pombe) 1.55412
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 1.55389
B9D1 B9 protein domain 1 1.55362
STRN3 striatin, calmodulin binding protein 3 1.55346
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 1.55328
PEX2 peroxisomal biogenesis factor 2 1.55103
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 1.54773
SNX25 sorting nexin 25 1.54753
NPAS3 neuronal PAS domain protein 3 1.54592
MZT1 mitotic spindle organizing protein 1 1.54545
ZMYM5 zinc finger, MYM-type 5 1.54398
MED23 mediator complex subunit 23 1.5435
FAM20B family with sequence similarity 20, member B 1.54348
MYH10 myosin, heavy chain 10, non-muscle 1.53834
UHRF1BP1L UHRF1 binding protein 1-like 1.53776
GMPS guanine monphosphate synthase 1.53593
ADGRG1 adhesion G protein-coupled receptor G1 1.53196
IKZF5 IKAROS family zinc finger 5 (Pegasus) 1.53165

decreased expression

Symbol Name Standardized Value
CERK ceramide kinase -3.56584
SCP2 sterol carrier protein 2 -3.51918
PLAC8 placenta-specific 8 -3.43143
SUSD3 sushi domain containing 3 -3.29104
RAB37 RAB37, member RAS oncogene family -3.00724
PLEKHO1 pleckstrin homology domain containing, family O member 1 -2.9624
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 -2.95624
MFSD1 major facilitator superfamily domain containing 1 -2.93573
MGST2 microsomal glutathione S-transferase 2 -2.89911
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.85028
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 -2.82127
TLR2 toll-like receptor 2 -2.8057
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 -2.78087
MYADM myeloid-associated differentiation marker -2.77558
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -2.76153
LYST lysosomal trafficking regulator -2.75503
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough -2.74759
GAPT GRB2-binding adaptor protein, transmembrane -2.74059
LAT2 linker for activation of T cells family, member 2 -2.72717
TSPAN4 tetraspanin 4 -2.71742
CCDC22 coiled-coil domain containing 22 -2.70173
FGR FGR proto-oncogene, Src family tyrosine kinase -2.69996
GRN granulin -2.68668
CARD16 caspase recruitment domain family, member 16 -2.6688
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -2.66362
SCN4B sodium channel, voltage gated, type IV beta subunit -2.65585
RNF216 ring finger protein 216 -2.65131
CLCN7 chloride channel, voltage-sensitive 7 -2.64949
LINC01278 long intergenic non-protein coding RNA 1278 -2.63383
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.63074
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -2.59533
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.5694
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.55296
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.54495
POGK pogo transposable element with KRAB domain -2.52811
ASGR1 asialoglycoprotein receptor 1 -2.51212
ZNF131 zinc finger protein 131 -2.50967
RHBDF2 rhomboid 5 homolog 2 (Drosophila) -2.49621
NAIP NLR family, apoptosis inhibitory protein -2.48485
SRGN serglycin -2.48308
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 -2.47003
SPRY2 sprouty homolog 2 (Drosophila) -2.46993
HPS5 Hermansky-Pudlak syndrome 5 -2.45763
FXYD5 FXYD domain containing ion transport regulator 5 -2.45072
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 -2.44411
CCDC106 coiled-coil domain containing 106 -2.43548
HCP5 HLA complex P5 (non-protein coding) -2.43179
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit -2.42503
RPL15 ribosomal protein L15 -2.38163
FMO4 flavin containing monooxygenase 4 -2.36135
PLBD1 phospholipase B domain containing 1 -2.35635
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.35338
MPV17 MpV17 mitochondrial inner membrane protein -2.34474
LAMP2 lysosomal-associated membrane protein 2 -2.33097
KIFC2 kinesin family member C2 -2.32679
MPRIP myosin phosphatase Rho interacting protein -2.30411
TMEM219 transmembrane protein 219 -2.29359
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -2.28979
SYK spleen tyrosine kinase -2.2632
SLC26A8 solute carrier family 26 (anion exchanger), member 8 -2.26109
LST1 leukocyte specific transcript 1 -2.25838
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2 -2.25132
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -2.24862
CYSLTR1 cysteinyl leukotriene receptor 1 -2.20198
SPI1 Spi-1 proto-oncogene -2.19961
TSPAN32 tetraspanin 32 -2.19239
PPP1R21 protein phosphatase 1, regulatory subunit 21 -2.19116
RILPL2 Rab interacting lysosomal protein-like 2 -2.19014
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.18676
MYH9 myosin, heavy chain 9, non-muscle -2.17346
CD14 CD14 molecule -2.17334
AFF3 AF4/FMR2 family, member 3 -2.16756
SIRPB1 signal-regulatory protein beta 1 -2.15678
GAS7 growth arrest-specific 7 -2.1562
CLSTN1 calsyntenin 1 -2.15229
KIAA1211L KIAA1211-like -2.15194
CTSS cathepsin S -2.15121
LOC606724 coronin, actin binding protein, 1A pseudogene -2.14895
PLD3 phospholipase D family, member 3 -2.14499
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.1433
LINC00936 long intergenic non-protein coding RNA 936 -2.13604
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 -2.13303
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.12396
LY86 lymphocyte antigen 86 -2.11874
NSF N-ethylmaleimide-sensitive factor -2.11832
PSAP prosaposin -2.11639
OSBPL5 oxysterol binding protein-like 5 -2.10552
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.09667
CUEDC1 CUE domain containing 1 -2.09613
GAMT guanidinoacetate N-methyltransferase -2.09451
SMAGP small cell adhesion glycoprotein -2.09374
MANBA mannosidase, beta A, lysosomal -2.07678
MSRB3 methionine sulfoxide reductase B3 -2.07228
FBN2 fibrillin 2 -2.06199
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -2.06135
SH2D3C SH2 domain containing 3C -2.05622
TSPO translocator protein (18kDa) -2.054
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.05221
PWWP2B PWWP domain containing 2B -2.04971
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma -2.044
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) -2.04177
HIPK2 homeodomain interacting protein kinase 2 -2.03488
RAB5C RAB5C, member RAS oncogene family -2.03191
SERF2 small EDRK-rich factor 2 -2.02797
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -2.0258
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -2.01938
DNAH1 dynein, axonemal, heavy chain 1 -2.0188
TRAK1 trafficking protein, kinesin binding 1 -2.01287
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.00624
HVCN1 hydrogen voltage gated channel 1 -1.9994
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -1.99688
TADA2B transcriptional adaptor 2B -1.99681
CSTA cystatin A (stefin A) -1.98887
ERP29 endoplasmic reticulum protein 29 -1.98816
SGSM2 small G protein signaling modulator 2 -1.98496
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -1.97124
SH3BP1 SH3-domain binding protein 1 -1.96807
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -1.96413
MFSD10 major facilitator superfamily domain containing 10 -1.96004
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -1.9432
PLEKHO2 pleckstrin homology domain containing, family O member 2 -1.94015
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -1.92414
DHRS4 dehydrogenase/reductase (SDR family) member 4 -1.92067
CTSA cathepsin A -1.9182
YPEL2 yippee-like 2 (Drosophila) -1.91736
ROPN1L rhophilin associated tail protein 1-like -1.91173
SLC45A4 solute carrier family 45, member 4 -1.9064
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) -1.90535
RRAGD Ras-related GTP binding D -1.9045
ZFHX3 zinc finger homeobox 3 -1.90324
KIAA0319L KIAA0319-like -1.89734
CFC1B cripto, FRL-1, cryptic family 1B -1.89224
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.89082
TPP1 tripeptidyl peptidase I -1.88233
CCR2 chemokine (C-C motif) receptor 2 -1.8794
PLIN3 perilipin 3 -1.86577
CLEC7A C-type lectin domain family 7, member A -1.8643
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 -1.86214
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 -1.86203
GNAS GNAS complex locus -1.85796
NPTN neuroplastin -1.85587
TMEM206 transmembrane protein 206 -1.85329
RUNX1 runt-related transcription factor 1 -1.84342
MMRN1 multimerin 1 -1.8427
MYO9B myosin IXB -1.83837
GMFG glia maturation factor, gamma -1.83818
RNASE3 ribonuclease, RNase A family, 3 -1.83132
DOCK2 dedicator of cytokinesis 2 -1.82925
CFP complement factor properdin -1.8284
ANGPTL6 angiopoietin-like 6 -1.82022
H2AFY H2A histone family, member Y -1.81608
ARHGAP27 Rho GTPase activating protein 27 -1.81596
C9ORF72 chromosome 9 open reading frame 72 -1.81561
EML3 echinoderm microtubule associated protein like 3 -1.81389
LPAR6 lysophosphatidic acid receptor 6 -1.8117
CX3CR1 chemokine (C-X3-C motif) receptor 1 -1.80648
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -1.8034
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.80093
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -1.79906
DGCR6 DiGeorge syndrome critical region gene 6 -1.79053
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -1.7793
TRAPPC5 trafficking protein particle complex 5 -1.77903
DUSP4 dual specificity phosphatase 4 -1.77129
ZNF669 zinc finger protein 669 -1.76472
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.76387
ADAM15 ADAM metallopeptidase domain 15 -1.76327
PYCARD PYD and CARD domain containing -1.76289
CEP350 centrosomal protein 350kDa -1.75522
NLRP3 NLR family, pyrin domain containing 3 -1.75234
TRIM8 tripartite motif containing 8 -1.75062
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -1.74833
POR P450 (cytochrome) oxidoreductase -1.74463
GPR160 G protein-coupled receptor 160 -1.74377
GAS6 growth arrest-specific 6 -1.73658
SVIL supervillin -1.73311
AIF1 allograft inflammatory factor 1 -1.73198
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -1.73108
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -1.72696
SH3BP2 SH3-domain binding protein 2 -1.72611
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.72523
SNX27 sorting nexin family member 27 -1.72315
RBM4B RNA binding motif protein 4B -1.72124
WAS Wiskott-Aldrich syndrome -1.7168
C10ORF11 chromosome 10 open reading frame 11 -1.71645
LTA4H leukotriene A4 hydrolase -1.7143
RHOG ras homolog family member G -1.71356
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase -1.71299
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B -1.70975
GPR162 G protein-coupled receptor 162 -1.70861
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.70809
NBPF9 neuroblastoma breakpoint family, member 9 -1.70636
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 -1.70614
TPM2 tropomyosin 2 (beta) -1.70342
GPSM3 G-protein signaling modulator 3 -1.70282
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -1.70085
DPEP2 dipeptidase 2 -1.69559
CNPY3 canopy FGF signaling regulator 3 -1.69271
TAGAP T-cell activation RhoGTPase activating protein -1.69268
EP400 E1A binding protein p400 -1.69207
ARRB1 arrestin, beta 1 -1.69153
BICD2 bicaudal D homolog 2 (Drosophila) -1.68963
EVA1B eva-1 homolog B (C. elegans) -1.68791
NAGK N-acetylglucosamine kinase -1.68701
PRKCD protein kinase C, delta -1.68558
RAP1GAP2 RAP1 GTPase activating protein 2 -1.68281
MATK megakaryocyte-associated tyrosine kinase -1.67977
CLNK cytokine-dependent hematopoietic cell linker -1.67773
PNKD paroxysmal nonkinesigenic dyskinesia -1.67708
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 -1.67551
SMIM14 small integral membrane protein 14 -1.67493
CD1E CD1e molecule -1.67218
CRTAP cartilage associated protein -1.6665
ZNF467 zinc finger protein 467 -1.66488
INSIG1 insulin induced gene 1 -1.66235
USF2 upstream transcription factor 2, c-fos interacting -1.65391
TOX thymocyte selection-associated high mobility group box -1.65301
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 -1.64684
CLIP2 CAP-GLY domain containing linker protein 2 -1.64374
ADPGK ADP-dependent glucokinase -1.64337
PLBD2 phospholipase B domain containing 2 -1.64327
C5 complement component 5 -1.64054
SPNS3 spinster homolog 3 (Drosophila) -1.63665
TNNI2 troponin I type 2 (skeletal, fast) -1.63208
INF2 inverted formin, FH2 and WH2 domain containing -1.63203
C5AR1 complement component 5a receptor 1 -1.63181
CCM2 cerebral cavernous malformation 2 -1.62835
DUSP3 dual specificity phosphatase 3 -1.62536
MSRB1 methionine sulfoxide reductase B1 -1.62467
THBS4 thrombospondin 4 -1.62234
CSF3R colony stimulating factor 3 receptor (granulocyte) -1.61953
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -1.61746
C16ORF93 chromosome 16 open reading frame 93 -1.61494
AK8 adenylate kinase 8 -1.61383
EML4 echinoderm microtubule associated protein like 4 -1.61337
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -1.61227
EHF ets homologous factor -1.61033
MTMR14 myotubularin related protein 14 -1.60538
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -1.60513
AKNA AT-hook transcription factor -1.60288
AZU1 azurocidin 1 -1.6021
SUN2 Sad1 and UNC84 domain containing 2 -1.60138
OSCAR osteoclast associated, immunoglobulin-like receptor -1.60074
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -1.60004
LPXN leupaxin -1.60003
DTX2 deltex 2, E3 ubiquitin ligase -1.59894
RALY RALY heterogeneous nuclear ribonucleoprotein -1.59799
POMT1 protein-O-mannosyltransferase 1 -1.59718
TBC1D13 TBC1 domain family, member 13 -1.59608
CBR3 carbonyl reductase 3 -1.5952
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.59364
TOM1 target of myb1 (chicken) -1.59312
TMEM131 transmembrane protein 131 -1.59257
NIN ninein (GSK3B interacting protein) -1.59156
CD33 CD33 molecule -1.59026
TPMT thiopurine S-methyltransferase -1.58884
LMO4 LIM domain only 4 -1.58537
MEF2D myocyte enhancer factor 2D -1.58521
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 -1.58431
HYAL3 hyaluronoglucosaminidase 3 -1.58224
ZDHHC6 zinc finger, DHHC-type containing 6 -1.58176
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -1.58141
LINC00202-2 long intergenic non-protein coding RNA 202-2 -1.58057
IGFBP7 insulin-like growth factor binding protein 7 -1.57842
NOTCH1 notch 1 -1.57685
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -1.57482
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -1.57436
ELMO2 engulfment and cell motility 2 -1.57235
SMCO4 single-pass membrane protein with coiled-coil domains 4 -1.56834
PILRA paired immunoglobin-like type 2 receptor alpha -1.56721
PTPRE protein tyrosine phosphatase, receptor type, E -1.56443
DDIT4L DNA-damage-inducible transcript 4-like -1.5644
NBPF11 neuroblastoma breakpoint family, member 11 -1.56284
GPRIN3 GPRIN family member 3 -1.56235
TP53I13 tumor protein p53 inducible protein 13 -1.56075
RAB4B RAB4B, member RAS oncogene family -1.56017
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -1.55658
BEND5 BEN domain containing 5 -1.55526
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -1.55421
RASAL3 RAS protein activator like 3 -1.55376
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -1.55069
GPR18 G protein-coupled receptor 18 -1.54631
TTC3 tetratricopeptide repeat domain 3 -1.54475
VGLL4 vestigial-like family member 4 -1.54461
ITGA7 integrin, alpha 7 -1.54446
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -1.54399
RRAGC Ras-related GTP binding C -1.53962
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -1.53656
ANKRD33 ankyrin repeat domain 33 -1.53601
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -1.53435
FGD3 FYVE, RhoGEF and PH domain containing 3 -1.5333
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -1.53233
TYMP thymidine phosphorylase -1.53135
PAM peptidylglycine alpha-amidating monooxygenase -1.53094
SUMF1 sulfatase modifying factor 1 -1.53075
LTC4S leukotriene C4 synthase -1.53071
SNX17 sorting nexin 17 -1.52777
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -1.52755
ALCAM activated leukocyte cell adhesion molecule -1.5264
TACSTD2 tumor-associated calcium signal transducer 2 -1.52154
TTC39C tetratricopeptide repeat domain 39C -1.51952
Funding