ABL2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ABL proto-oncogene 2, non-receptor tyrosine kinase|This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 27)
External Link https://ncbi.nlm.nih.gov/gene/27
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Genes

500 genes differentially expressed following the ABL2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0156387
IFI27 interferon, alpha-inducible protein 27 0.0144335
MX1 MX dynamin-like GTPase 1 0.0123421
CRABP2 cellular retinoic acid binding protein 2 0.0121681
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0116955
GRN granulin 0.0116385
AIM2 absent in melanoma 2 0.0115281
TENT5A terminal nucleotidyltransferase 5A 0.0114541
CXCL14 chemokine (C-X-C motif) ligand 14 0.0114014
ANXA2P2 annexin A2 pseudogene 2 0.0112524
IFI44L interferon-induced protein 44-like 0.0112197
HSPA1A heat shock 70kDa protein 1A 0.0110121
S100A10 S100 calcium binding protein A10 0.0110002
IL18 interleukin 18 0.0109682
JPT1 Jupiter microtubule associated homolog 1 0.0107113
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0105663
ISG15 ISG15 ubiquitin-like modifier 0.0104076
KRT14 keratin 14, type I 0.0103768
BTG1 B-cell translocation gene 1, anti-proliferative 0.0102653
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.0100691
MFSD10 major facilitator superfamily domain containing 10 0.0100641
CXADR coxsackie virus and adenovirus receptor 0.0100617
ANXA2 annexin A2 0.00996848
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00979033
NCK1 NCK adaptor protein 1 0.0097345
HIST1H2BD histone cluster 1, H2bd 0.00972483
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0097074
RRAGC Ras-related GTP binding C 0.00965124
CCNG2 cyclin G2 0.00963947
AHNAK AHNAK nucleoprotein 0.00943717
SCPEP1 serine carboxypeptidase 1 0.00940758
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00931477
BEX1 brain expressed, X-linked 1 0.00926149
KRT17 keratin 17, type I 0.00920628
SCGB2A2 secretoglobin, family 2A, member 2 0.00916152
REEP5 receptor accessory protein 5 0.00910045
TM4SF1 transmembrane 4 L six family member 1 0.00909725
FNDC3B fibronectin type III domain containing 3B 0.00908487
CAV1 caveolin 1, caveolae protein, 22kDa 0.00901706
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00898504
MYOF myoferlin 0.00898119
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00897122
MELK maternal embryonic leucine zipper kinase 0.00896224
FABP4 fatty acid binding protein 4, adipocyte 0.00893557
TGFBI transforming growth factor, beta-induced, 68kDa 0.00882081
HEATR1 HEAT repeat containing 1 0.00868352
KCTD12 potassium channel tetramerization domain containing 12 0.00864147
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00857542
APOD apolipoprotein D 0.00854002
IFI44 interferon-induced protein 44 0.008448
HSPB8 heat shock 22kDa protein 8 0.00842041
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00836954
CAV2 caveolin 2 0.00835187
TP63 tumor protein p63 0.00835179
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00832034
TRIM22 tripartite motif containing 22 0.00829676
CFD complement factor D (adipsin) 0.0082399
STK17A serine/threonine kinase 17a 0.00821505
ADM adrenomedullin 0.00820955
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00820719
FGFBP1 fibroblast growth factor binding protein 1 0.00820698
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00818197
BST2 bone marrow stromal cell antigen 2 0.00817944
RPL36 ribosomal protein L36 0.00816788
MVP major vault protein 0.00816296
IVL involucrin 0.00814142
HIST1H2AC histone cluster 1, H2ac 0.00808562
PRPH peripherin 0.00807411
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.00805785
PTHLH parathyroid hormone-like hormone 0.00798444
SPRR1A small proline-rich protein 1A 0.00798017
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00792665
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00791007
CSRP2 cysteine and glycine-rich protein 2 0.00788666
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00787232
NES nestin 0.00786268
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00785665
SPRR1B small proline-rich protein 1B 0.0078525
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00776501
CA2 carbonic anhydrase II 0.00775607
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00775141
RAB9A RAB9A, member RAS oncogene family 0.0077366
TUBB2A tubulin, beta 2A class IIa 0.00773523
ACTB actin, beta 0.00770886
HIST1H2BK histone cluster 1, H2bk 0.0076825
MBNL2 muscleblind-like splicing regulator 2 0.00767183
AREG amphiregulin 0.00766866
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00756567
IL1RN interleukin 1 receptor antagonist 0.00756316
MATN2 matrilin 2 0.0075152
USP6NL USP6 N-terminal like 0.00750199
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00746399
SNX7 sorting nexin 7 0.00746351
GPATCH8 G patch domain containing 8 0.00745996
LY6D lymphocyte antigen 6 complex, locus D 0.00744932
GLA galactosidase, alpha 0.00743368
GNS glucosamine (N-acetyl)-6-sulfatase 0.00741292
ARL4A ADP-ribosylation factor-like 4A 0.00739629
KLF6 Kruppel-like factor 6 0.00739588
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00738004
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00734914
RBM47 RNA binding motif protein 47 0.00730678
COL17A1 collagen, type XVII, alpha 1 0.00730392
SLC38A1 solute carrier family 38, member 1 0.00728022
INHBB inhibin, beta B 0.00726264
PGAM1 phosphoglycerate mutase 1 (brain) 0.00724519
RPS17 ribosomal protein S17 0.00723573
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00723506
RAB1A RAB1A, member RAS oncogene family 0.00720717
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00719322
CSTA cystatin A (stefin A) 0.00718847
RUFY3 RUN and FYVE domain containing 3 0.0071477
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00714554
CA12 carbonic anhydrase XII 0.00713568
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00713491
IGFBP6 insulin-like growth factor binding protein 6 0.00711342
MYO1B myosin IB 0.00710262
EMP1 epithelial membrane protein 1 0.00709967
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00708092
STMN2 stathmin 2 0.00707166
HNMT histamine N-methyltransferase 0.00705278
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00704187
ANXA5 annexin A5 0.00703171
NOTCH2NL notch 2 N-terminal like 0.00703121
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0070139
FZD2 frizzled class receptor 2 0.00701197
ACTC1 actin, alpha, cardiac muscle 1 0.00698017
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00697474
EDNRB endothelin receptor type B 0.00694436
PELI1 pellino E3 ubiquitin protein ligase 1 0.00692851
PLK2 polo-like kinase 2 0.0069285
RTN4 reticulon 4 0.00690418
KRT1 keratin 1, type II 0.00689137
GAL galanin/GMAP prepropeptide 0.00685447
SPON2 spondin 2, extracellular matrix protein 0.00683975
TGFBR3 transforming growth factor, beta receptor III 0.00682127
LGALS4 lectin, galactoside-binding, soluble, 4 0.00678761
TOM1L1 target of myb1 (chicken)-like 1 0.00678534
HSPA4L heat shock 70kDa protein 4-like 0.00677506
ISG20 interferon stimulated exonuclease gene 20kDa 0.00675253
DMTF1 cyclin D binding myb-like transcription factor 1 0.00674125
TMEM45A transmembrane protein 45A 0.00674104
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00673142
ZNF430 zinc finger protein 430 0.0067197
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00671814
UBB ubiquitin B 0.00671291
MYCBP MYC binding protein 0.00668979
LHFPL2 lipoma HMGIC fusion partner-like 2 0.00660865
SOX9 SRY (sex determining region Y)-box 9 0.00659794
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00659745
CXCL10 chemokine (C-X-C motif) ligand 10 0.00659519
COL15A1 collagen, type XV, alpha 1 0.0065922
XAF1 XIAP associated factor 1 0.00659197
TPBG trophoblast glycoprotein 0.00651345
HBP1 HMG-box transcription factor 1 0.00650917
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00649255
ATF3 activating transcription factor 3 0.00648984
ADGRL2 adhesion G protein-coupled receptor L2 0.00648687
XIC X chromosome inactivation center 0.00646875
ABHD3 abhydrolase domain containing 3 0.00646151
SERINC1 serine incorporator 1 0.00646017
SPAG9 sperm associated antigen 9 0.0064594
SCGB1D2 secretoglobin, family 1D, member 2 0.00643654
DSG3 desmoglein 3 0.00643564
ENAH enabled homolog (Drosophila) 0.00643489
HIST1H2BH histone cluster 1, H2bh 0.00642823
TUBB2B tubulin, beta 2B class IIb 0.00641612
CTSG cathepsin G 0.00641509
LGALS1 lectin, galactoside-binding, soluble, 1 0.0064145
TM4SF4 transmembrane 4 L six family member 4 0.0064105
GOLGA8A golgin A8 family, member A 0.00640877
FN1 fibronectin 1 0.00637554
BAG3 BCL2-associated athanogene 3 0.00636031
CLIP1 CAP-GLY domain containing linker protein 1 0.00635739
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00635125
SCAF11 SR-related CTD-associated factor 11 0.00634731
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00634412
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.00634373
MGLL monoglyceride lipase 0.00634065
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00633023
OASL 2'-5'-oligoadenylate synthetase-like 0.00632748
PWP1 PWP1 homolog (S. cerevisiae) 0.00632581
ACLY ATP citrate lyase 0.00630547
KLK5 kallikrein-related peptidase 5 0.00629929
NIT1 nitrilase 1 0.0062581
MAB21L1 mab-21-like 1 (C. elegans) 0.00622418
PLAAT3 phospholipase A and acyltransferase 3 0.00622329
ASPH aspartate beta-hydroxylase 0.00619771
OLFML2A olfactomedin-like 2A 0.00619671
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.006193
BCL3 B-cell CLL/lymphoma 3 0.00618001
ANXA3 annexin A3 0.00617917
ACSL4 acyl-CoA synthetase long-chain family member 4 0.0061227
CXCL5 chemokine (C-X-C motif) ligand 5 0.0061083
DPP8 dipeptidyl-peptidase 8 0.00610111
ITGB4 integrin, beta 4 0.00608669
ARMCX3 armadillo repeat containing, X-linked 3 0.00607635
NELL1 NEL-like 1 (chicken) 0.00607485
KIF5B kinesin family member 5B 0.0060616
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.00605651
TAOK3 TAO kinase 3 0.00604519
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.00603366
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00602559
RGS5 regulator of G-protein signaling 5 0.00602535
ARID5B AT rich interactive domain 5B (MRF1-like) 0.00601157
CCDC68 coiled-coil domain containing 68 0.0059964
KRT10 keratin 10, type I 0.00599286
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00597238
RXYLT1 ribitol xylosyltransferase 1 0.00596771
FGD6 FYVE, RhoGEF and PH domain containing 6 0.00595367
PRSS23 protease, serine, 23 0.00594927
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.00594284
ZBTB43 zinc finger and BTB domain containing 43 0.00594146
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00593359
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00592493
NFE2L2 nuclear factor, erythroid 2-like 2 0.00590162
GUSBP3 glucuronidase, beta pseudogene 3 0.00590056
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.0058992
DDIT3 DNA-damage-inducible transcript 3 0.00589828
MIR22HG MIR22 host gene 0.00588677
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.00586991
CRABP1 cellular retinoic acid binding protein 1 0.0058699
TTR transthyretin 0.00586345
MPZ myelin protein zero 0.00585697
CSNK1A1 casein kinase 1, alpha 1 0.00583438
MXI1 MAX interactor 1, dimerization protein 0.0058268
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0058159
NFIB nuclear factor I/B 0.00581046
SGCE sarcoglycan, epsilon 0.00580445
BRD2 bromodomain containing 2 0.00579497
EGR1 early growth response 1 0.0057856
CYB5A cytochrome b5 type A (microsomal) 0.00578548
TRIB3 tribbles pseudokinase 3 0.00578441
ZMAT3 zinc finger, matrin-type 3 0.00576904
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.0057669
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00576096
SPRR2B small proline-rich protein 2B 0.00575694
MRPS30 mitochondrial ribosomal protein S30 0.00575248
RSL1D1 ribosomal L1 domain containing 1 0.00574175
SEPP1 selenoprotein P, plasma, 1 0.00573098
ZYX zyxin 0.00572316
MED13 mediator complex subunit 13 0.00572175
CANX calnexin 0.00571892
BRD4 bromodomain containing 4 0.00571771
S100A11 S100 calcium binding protein A11 0.00571106
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.005706
RND3 Rho family GTPase 3 0.0057041
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00569324
SOWAHC sosondowah ankyrin repeat domain family member C 0.0056843
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00568109

decreased expression

Symbol Name Standardized Value
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.0125816
WT1 Wilms tumor 1 -0.0123609
MYH10 myosin, heavy chain 10, non-muscle -0.0122844
EPCAM epithelial cell adhesion molecule -0.0117796
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0114444
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0113318
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0108485
RPIA ribose 5-phosphate isomerase A -0.0107313
LAPTM4B lysosomal protein transmembrane 4 beta -0.0106589
PCP4 Purkinje cell protein 4 -0.0103685
BGN biglycan -0.0101364
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.0100137
PRUNE2 prune homolog 2 (Drosophila) -0.00996651
LCN2 lipocalin 2 -0.00994511
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0099198
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.00970029
RNF144A ring finger protein 144A -0.00961343
MAGED1 melanoma antigen family D1 -0.0095993
PCNA proliferating cell nuclear antigen -0.00956491
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0095454
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.00938168
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00913411
MUC16 mucin 16, cell surface associated -0.00905907
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00900257
ODC1 ornithine decarboxylase 1 -0.00897134
RNF167 ring finger protein 167 -0.008946
ITM2C integral membrane protein 2C -0.00893908
XYLT1 xylosyltransferase I -0.00890573
KIAA0100 KIAA0100 -0.0088568
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0088204
SLC44A4 solute carrier family 44, member 4 -0.00880001
PTGIS prostaglandin I2 (prostacyclin) synthase -0.0087866
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00877332
RGS1 regulator of G-protein signaling 1 -0.00869922
MSLN mesothelin -0.00868562
CLDN3 claudin 3 -0.00866131
MT1M metallothionein 1M -0.00861781
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00853439
GCH1 GTP cyclohydrolase 1 -0.0085225
MAP7 microtubule-associated protein 7 -0.00850024
MSMB microseminoprotein, beta- -0.00829141
AEBP1 AE binding protein 1 -0.00826347
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00820565
PTPRD protein tyrosine phosphatase, receptor type, D -0.0080899
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00805768
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.00803038
NNMT nicotinamide N-methyltransferase -0.00793829
CLDN10 claudin 10 -0.0078802
MCM6 minichromosome maintenance complex component 6 -0.00787848
COL1A2 collagen, type I, alpha 2 -0.00786113
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00785182
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00783812
GNAS GNAS complex locus -0.0078347
CDC20 cell division cycle 20 -0.00779918
CHN2 chimerin 2 -0.00779824
POMZP3 POM121 and ZP3 fusion -0.00775882
H2AX H2A.X variant histone -0.00775351
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00774394
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00768934
ASPN asporin -0.00767728
TST thiosulfate sulfurtransferase (rhodanese) -0.00761487
IRS2 insulin receptor substrate 2 -0.0076085
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00759407
DSCC1 DNA replication and sister chromatid cohesion 1 -0.00759048
AOC1 amine oxidase, copper containing 1 -0.00758972
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00755284
FBXO21 F-box protein 21 -0.00743857
WWOX WW domain containing oxidoreductase -0.00741275
SKI SKI proto-oncogene -0.00738641
KRT19 keratin 19, type I -0.00730651
CDK8 cyclin-dependent kinase 8 -0.00725659
MB myoglobin -0.00723925
S100P S100 calcium binding protein P -0.00723094
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00720299
ZCCHC14 zinc finger, CCHC domain containing 14 -0.00719761
VDAC3 voltage-dependent anion channel 3 -0.00719009
QPCT glutaminyl-peptide cyclotransferase -0.00718014
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00717915
INHBA inhibin, beta A -0.00715894
MLF1 myeloid leukemia factor 1 -0.00715514
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00715377
ACP5 acid phosphatase 5, tartrate resistant -0.00708457
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00707038
ZBTB18 zinc finger and BTB domain containing 18 -0.00706836
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00705941
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00705599
STK10 serine/threonine kinase 10 -0.0070516
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00704354
LMNB1 lamin B1 -0.0070051
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00695652
ANPEP alanyl (membrane) aminopeptidase -0.00694682
FGFR3 fibroblast growth factor receptor 3 -0.00694495
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00693826
NUSAP1 nucleolar and spindle associated protein 1 -0.00692467
LYZ lysozyme -0.00689909
ADCY2 adenylate cyclase 2 (brain) -0.00683883
ATP7B ATPase, Cu++ transporting, beta polypeptide -0.00682876
MAL mal, T-cell differentiation protein -0.00682634
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00682299
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -0.00682028
ESRP1 epithelial splicing regulatory protein 1 -0.00680975
RRBP1 ribosome binding protein 1 -0.0067874
TRIB2 tribbles pseudokinase 2 -0.00676428
TRMT5 tRNA methyltransferase 5 -0.0067413
RAD23B RAD23 homolog B (S. cerevisiae) -0.00669199
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00666587
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.00665472
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00664261
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00663494
CCDC92 coiled-coil domain containing 92 -0.00662473
MAN1C1 mannosidase, alpha, class 1C, member 1 -0.00661822
TSPAN4 tetraspanin 4 -0.00661682
TARDBP TAR DNA binding protein -0.00661589
FAM171A1 family with sequence similarity 171, member A1 -0.00658961
CADPS2 Ca++-dependent secretion activator 2 -0.00657573
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00653741
CBFB core-binding factor, beta subunit -0.00651844
COG2 component of oligomeric golgi complex 2 -0.00651044
CHKB choline kinase beta -0.00650142
NRGN neurogranin (protein kinase C substrate, RC3) -0.00647562
DHCR24 24-dehydrocholesterol reductase -0.00646755
EMX2 empty spiracles homeobox 2 -0.00643129
CPVL carboxypeptidase, vitellogenic-like -0.00642679
MRPL57 mitochondrial ribosomal protein L57 -0.00641989
KRCC1 lysine-rich coiled-coil 1 -0.00640636
PDS5B PDS5 cohesin associated factor B -0.00640263
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.0063991
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00639697
CRYM crystallin, mu -0.00637344
PDLIM3 PDZ and LIM domain 3 -0.00635884
NUDCD3 NudC domain containing 3 -0.00634065
TBC1D31 TBC1 domain family, member 31 -0.00630865
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00629799
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -0.00628937
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.0062791
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -0.00626943
IL1R1 interleukin 1 receptor, type I -0.00623239
SULF1 sulfatase 1 -0.00621244
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00620516
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00618932
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00616385
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00615188
TEX30 testis expressed 30 -0.00613974
MGAM maltase-glucoamylase -0.00609393
HMGB2 high mobility group box 2 -0.00607823
MCM4 minichromosome maintenance complex component 4 -0.00607265
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00605136
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00603885
HDAC4 histone deacetylase 4 -0.00602738
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00601889
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00598595
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00597111
COPS7A COP9 signalosome subunit 7A -0.00596546
CLEC11A C-type lectin domain family 11, member A -0.00594329
KAZN kazrin, periplakin interacting protein -0.00594147
TOR1A torsin family 1, member A (torsin A) -0.00594047
MAVS mitochondrial antiviral signaling protein -0.0059262
DCK deoxycytidine kinase -0.00591088
ADI1 acireductone dioxygenase 1 -0.00590529
PEX11A peroxisomal biogenesis factor 11 alpha -0.00588473
TBC1D16 TBC1 domain family, member 16 -0.00584822
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00584646
IFRD2 interferon-related developmental regulator 2 -0.00584206
STAU2 staufen double-stranded RNA binding protein 2 -0.00583027
CCL20 chemokine (C-C motif) ligand 20 -0.00582991
TXNDC9 thioredoxin domain containing 9 -0.00582509
MCM5 minichromosome maintenance complex component 5 -0.00582458
NKX2-2 NK2 homeobox 2 -0.00582258
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00581798
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00580134
TEAD4 TEA domain family member 4 -0.00580079
INTS6 integrator complex subunit 6 -0.00578272
PHYH phytanoyl-CoA 2-hydroxylase -0.0057806
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0057786
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00577751
NPY neuropeptide Y -0.0057764
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.00577565
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00577273
CRISP3 cysteine-rich secretory protein 3 -0.00575516
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00569573
MCM2 minichromosome maintenance complex component 2 -0.00568488
THBS2 thrombospondin 2 -0.005681
CRNKL1 crooked neck pre-mRNA splicing factor 1 -0.00567919
AUTS2 autism susceptibility candidate 2 -0.00564223
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00564072
ACP3 acid phosphatase 3 -0.00563699
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00562824
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00562259
GCHFR GTP cyclohydrolase I feedback regulator -0.00561626
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00561043
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00557403
KPNA3 karyopherin alpha 3 (importin alpha 4) -0.0055706
LUM lumican -0.0055631
TSPYL5 TSPY-like 5 -0.00556281
SLC2A4RG SLC2A4 regulator -0.00556272
HMGB1 high mobility group box 1 -0.00554832
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.00553672
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.00552877
ZNF318 zinc finger protein 318 -0.0055205
IFT52 intraflagellar transport 52 -0.00551735
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00550197
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.00549579
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00547473
FTH1 ferritin, heavy polypeptide 1 -0.0054685
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.0054622
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00545773
FOXM1 forkhead box M1 -0.00545354
H2AFV H2A histone family, member V -0.00545022
HMGN2 high mobility group nucleosomal binding domain 2 -0.0054437
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.00544128
COL11A1 collagen, type XI, alpha 1 -0.00543287
DGKZ diacylglycerol kinase, zeta -0.00543154
CPB1 carboxypeptidase B1 (tissue) -0.00542529
COMP cartilage oligomeric matrix protein -0.00541798
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.00541147
MEIS1 Meis homeobox 1 -0.00540654
STARD7 StAR-related lipid transfer (START) domain containing 7 -0.00540415
NLGN4X neuroligin 4, X-linked -0.00539549
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00538691
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00538441
WFDC2 WAP four-disulfide core domain 2 -0.00537491
HPCAL1 hippocalcin-like 1 -0.00537332
PLXNB1 plexin B1 -0.00536839
PELI2 pellino E3 ubiquitin protein ligase family member 2 -0.00536144
PLN phospholamban -0.00534229
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00534104
EIF3L eukaryotic translation initiation factor 3, subunit L -0.00534012
MLPH melanophilin -0.00533805
CEL carboxyl ester lipase -0.00533588
DHFR dihydrofolate reductase -0.00532584
SIDT2 SID1 transmembrane family, member 2 -0.0053248
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.00529718
RFC3 replication factor C (activator 1) 3, 38kDa -0.00528805
ARHGAP6 Rho GTPase activating protein 6 -0.00528077
HAT1 histone acetyltransferase 1 -0.00527519
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00527515
TNS1 tensin 1 -0.00527273
SEH1L SEH1-like (S. cerevisiae) -0.00527178
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00527111
USP1 ubiquitin specific peptidase 1 -0.00525823
ATG4B autophagy related 4B, cysteine peptidase -0.00525672
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00525352
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -0.00524618
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00524039
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00523424
PDZRN3 PDZ domain containing ring finger 3 -0.00521899
DNM3 dynamin 3 -0.00521722
CCNA2 cyclin A2 -0.00520159
SDC1 syndecan 1 -0.00519523
BRCA1 breast cancer 1, early onset -0.00518812