ABL2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ABL proto-oncogene 2, non-receptor tyrosine kinase|This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 27)
External Link http://www.ncbi.nlm.nih.gov/gene/27
Similar Terms
Downloads & Tools

Genes

316 interacting proteins for ABL2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAD11 acyl-CoA dehydrogenase family, member 11
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACTB actin, beta
ACTN4 actinin, alpha 4
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ADAM28 ADAM metallopeptidase domain 28
ADCK1 aarF domain containing kinase 1
ADCK3 aarF domain containing kinase 3
ADK adenosine kinase
AFF4 AF4/FMR2 family, member 4
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AHRR aryl-hydrocarbon receptor repressor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIP aryl hydrocarbon receptor interacting protein
ALDOA aldolase A, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ALPK3 alpha-kinase 3
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANXA2 annexin A2
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAD3B ATPase family, AAA domain containing 3B
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AXL AXL receptor tyrosine kinase
AZI2 5-azacytidine induced 2
BCR breakpoint cluster region
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP2K BMP2 inducible kinase
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD3 bromodomain containing 3
BRD4 bromodomain containing 4
BTK Bruton agammaglobulinemia tyrosine kinase
C15ORF48 chromosome 15 open reading frame 48
C2CD5 C2 calcium-dependent domain containing 5
C6ORF25 chromosome 6 open reading frame 25
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASS4 Cas scaffolding protein family member 4
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNH cyclin H
CD84 CD84 molecule
CDC37 cell division cycle 37
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK12 cyclin-dependent kinase 12
CDK13 cyclin-dependent kinase 13
CDK2 cyclin-dependent kinase 2
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLK1 CDC-like kinase 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK1G1 casein kinase 1, gamma 1
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTTN cortactin
DCK deoxycytidine kinase
DCTPP1 dCTP pyrophosphatase 1
DDR1 discoidin domain receptor tyrosine kinase 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDC4 enhancer of mRNA decapping 4
EGFR epidermal growth factor receptor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3J eukaryotic translation initiation factor 3, subunit J
EPHA2 EPH receptor A2
EPHA5 EPH receptor A5
EPHA7 EPH receptor A7
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
EPHB4 EPH receptor B4
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
FBXO38 F-box protein 38
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FKBPL FK506 binding protein like
FRK fyn-related Src family tyrosine kinase
FRYL FRY-like
FYN FYN proto-oncogene, Src family tyrosine kinase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAK cyclin G associated kinase
GAPVD1 GTPase activating protein and VPS9 domains 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLMN glomulin, FKBP associated protein
GPX1 glutathione peroxidase 1
GRAMD1A GRAM domain containing 1A
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HCK HCK proto-oncogene, Src family tyrosine kinase
HIPK1 homeodomain interacting protein kinase 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HRAS Harvey rat sarcoma viral oncogene homolog
HRNR hornerin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPPL1 inositol polyphosphate phosphatase-like 1
INSR insulin receptor
IRAK1 interleukin-1 receptor-associated kinase 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KIAA0195 KIAA0195
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LGALS3 lectin, galactoside-binding, soluble, 3
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LRRK2 leucine-rich repeat kinase 2
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MED28 mediator complex subunit 28
MELK maternal embryonic leucine zipper kinase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEK11 NIMA-related kinase 11
NEK9 NIMA-related kinase 9
NLK nemo-like kinase
NQO2 NAD(P)H dehydrogenase, quinone 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUP98 nucleoporin 98kDa
OIP5 Opa interacting protein 5
ONECUT1 one cut homeobox 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDE4A phosphodiesterase 4A, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PKM pyruvate kinase, muscle
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN1 protein kinase N1
PKN3 protein kinase N3
PLCG1 phospholipase C, gamma 1
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
PPID peptidylprolyl isomerase D
PPP5C protein phosphatase 5, catalytic subunit
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKCQ protein kinase C, theta
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAE1 ribonucleic acid export 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RIN1 Ras and Rab interactor 1
RIPK2 receptor-interacting serine-threonine kinase 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPAP3 RNA polymerase II associated protein 3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SACK1A scaffolding CK1 anchoring protein A
SEC16A SEC16 homolog A (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK2 salt-inducible kinase 2
SIK3 SIK family kinase 3
SIVA1 SIVA1, apoptosis-inducing factor
SKP1 S-phase kinase-associated protein 1
SLK STE20-like kinase
SMYD3 SET and MYND domain containing 3
SORBS2 sorbin and SH3 domain containing 2
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPEG SPEG complex locus
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM2 serine/arginine repetitive matrix 2
SSB Sjogren syndrome antigen B (autoantigen La)
STK16 serine/threonine kinase 16
STK4 serine/threonine kinase 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYK spleen tyrosine kinase
SYNE2 spectrin repeat containing, nuclear envelope 2
TANK TRAF family member-associated NFKB activator
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBK1 TANK-binding kinase 1
TBKBP1 TBK1 binding protein 1
TEC tec protein tyrosine kinase
TESK2 testis-specific kinase 2
TGFBR1 transforming growth factor, beta receptor 1
TMX1 thioredoxin-related transmembrane protein 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNIK TRAF2 and NCK interacting kinase
TNK1 tyrosine kinase, non-receptor, 1
TNK2 tyrosine kinase, non-receptor, 2
TOMM34 translocase of outer mitochondrial membrane 34
TPD52L1 tumor protein D52-like 1
TRAF2 TNF receptor-associated factor 2
TRIM28 tripartite motif containing 28
TRIP10 thyroid hormone receptor interactor 10
TTBK2 tau tubulin kinase 2
TTC4 tetratricopeptide repeat domain 4
TTC9C tetratricopeptide repeat domain 9C
TTN titin
TUBA1B tubulin, alpha 1b
TYK2 tyrosine kinase 2
UBASH3A ubiquitin associated and SH3 domain containing A
UBASH3B ubiquitin associated and SH3 domain containing B
ULK3 unc-51 like kinase 3
UNC45A unc-45 homolog A (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USP19 ubiquitin specific peptidase 19
WEE1 WEE1 G2 checkpoint kinase
YES1 YES proto-oncogene 1, Src family tyrosine kinase