ABO Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)|This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 28)
External Link http://www.ncbi.nlm.nih.gov/gene/28
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117 interacting proteins for ABO from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ANXA11 annexin A11
ANXA6 annexin A6
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARF1 ADP-ribosylation factor 1
ARF5 ADP-ribosylation factor 5
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
CAND1 cullin-associated and neddylation-dissociated 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CCDC53 coiled-coil domain containing 53
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD81 CD81 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDK1 cyclin-dependent kinase 1
CFL1 cofilin 1 (non-muscle)
CHMP4B charged multivesicular body protein 4B
CLDN3 claudin 3
CLTC clathrin, heavy chain (Hc)
CNN2 calponin 2
COPB1 coatomer protein complex, subunit beta 1
COPZ1 coatomer protein complex, subunit zeta 1
CPNE1 copine I
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSK c-src tyrosine kinase
DNM2 dynamin 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EML4 echinoderm microtubule associated protein like 4
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EZR ezrin
FAM21C family with sequence similarity 21, member C
FEN1 flap structure-specific endonuclease 1
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
KIAA1033 KIAA1033
KIF5B kinesin family member 5B
KPNB1 karyopherin (importin) beta 1
LDHA lactate dehydrogenase A
LRRC57 leucine rich repeat containing 57
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGED2 melanoma antigen family D2
MAP4 microtubule-associated protein 4
MARCKSL1 MARCKS-like 1
MSN moesin
MX1 MX dynamin-like GTPase 1
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYO1D myosin ID
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
PLEC plectin
PLXNB2 plexin B2
PRRC1 proline-rich coiled-coil 1
PTGFRN prostaglandin F2 receptor inhibitor
RAB11A RAB11A, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALB v-ral simian leukemia viral oncogene homolog B
RANGAP1 Ran GTPase activating protein 1
RDX radixin
RHOC ras homolog family member C
RHOG ras homolog family member G
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SAMHD1 SAM domain and HD domain 1
SARNP SAP domain containing ribonucleoprotein
SEPT11 septin 11
SEPT2 septin 2
SEPT7 septin 7
SEPT9 septin 9
SLK STE20-like kinase
SNX2 sorting nexin 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP54 signal recognition particle 54kDa
SRP68 signal recognition particle 68kDa
SRP72 signal recognition particle 72kDa
SSRP1 structure specific recognition protein 1
STX3 syntaxin 3
TPD52 tumor protein D52
TRAPPC3 trafficking protein particle complex 3
TRIM28 tripartite motif containing 28
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VSNL1 visinin-like 1