| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | angiotensin I converting enzyme|This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 1636) |
| External Link | https://ncbi.nlm.nih.gov/gene/1636 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the ACE gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPB1 | heat shock 27kDa protein 1 | 0.0248444 |
| S100P | S100 calcium binding protein P | 0.0171687 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0169787 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0152467 |
| NEBL | nebulette | 0.0149563 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0135523 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0130353 |
| LCN2 | lipocalin 2 | 0.0128637 |
| YBX3 | Y box binding protein 3 | 0.0127797 |
| MAL | mal, T-cell differentiation protein | 0.0122956 |
| MGP | matrix Gla protein | 0.0118214 |
| XIC | X chromosome inactivation center | 0.0113696 |
| STC1 | stanniocalcin 1 | 0.0113177 |
| EPCAM | epithelial cell adhesion molecule | 0.0111529 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0110851 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0110668 |
| MX1 | MX dynamin-like GTPase 1 | 0.0110433 |
| TFF1 | trefoil factor 1 | 0.0110046 |
| PRKCA | protein kinase C, alpha | 0.0108651 |
| TRIM29 | tripartite motif containing 29 | 0.0108586 |
| PRAME | preferentially expressed antigen in melanoma | 0.0108534 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0108532 |
| GPM6B | glycoprotein M6B | 0.0106049 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0106002 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0105897 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0100493 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0100404 |
| EGR1 | early growth response 1 | 0.00998932 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00997287 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00985296 |
| ASS1 | argininosuccinate synthase 1 | 0.00983165 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00968342 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00957297 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0095066 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00938335 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00930617 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00928654 |
| KRT19 | keratin 19, type I | 0.00922293 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00920677 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00917487 |
| COCH | cochlin | 0.00911496 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00902156 |
| PTCH1 | patched 1 | 0.0089973 |
| COG7 | component of oligomeric golgi complex 7 | 0.00889215 |
| TXLNA | taxilin alpha | 0.00869672 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00869156 |
| DEFB1 | defensin, beta 1 | 0.00867807 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00858289 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.0085686 |
| DST | dystonin | 0.00852044 |
| KLK11 | kallikrein-related peptidase 11 | 0.00851588 |
| SYT1 | synaptotagmin I | 0.00842457 |
| CALB1 | calbindin 1, 28kDa | 0.00839058 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00838091 |
| PER1 | period circadian clock 1 | 0.00836926 |
| FGF13 | fibroblast growth factor 13 | 0.00829872 |
| AUTS2 | autism susceptibility candidate 2 | 0.00829684 |
| GNAS | GNAS complex locus | 0.00828928 |
| CHGB | chromogranin B | 0.00826428 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00824014 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00822067 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.0082 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00818804 |
| KLK6 | kallikrein-related peptidase 6 | 0.00817523 |
| SVIL | supervillin | 0.00813898 |
| INSR | insulin receptor | 0.00810267 |
| MYO5C | myosin VC | 0.00805727 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00805225 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.008029 |
| MMP7 | matrix metallopeptidase 7 | 0.00796711 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00792253 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00790919 |
| TGM2 | transglutaminase 2 | 0.00790183 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00790063 |
| LAMB1 | laminin, beta 1 | 0.00789857 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00785087 |
| ZNF318 | zinc finger protein 318 | 0.00781909 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.0078186 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00777102 |
| IRS2 | insulin receptor substrate 2 | 0.00776554 |
| KLK10 | kallikrein-related peptidase 10 | 0.007757 |
| GPATCH8 | G patch domain containing 8 | 0.00774086 |
| PSCA | prostate stem cell antigen | 0.00770884 |
| PCDH9 | protocadherin 9 | 0.00770847 |
| LETMD1 | LETM1 domain containing 1 | 0.00767959 |
| KYNU | kynureninase | 0.00767577 |
| RRBP1 | ribosome binding protein 1 | 0.00762795 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00761429 |
| USP18 | ubiquitin specific peptidase 18 | 0.00760609 |
| OGA | O-GlcNAcase | 0.00759433 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00757592 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00756826 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.00750198 |
| FOSL2 | FOS-like antigen 2 | 0.0075007 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00749531 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00746242 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00745522 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.0074344 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00742852 |
| TAC1 | tachykinin, precursor 1 | 0.00742336 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.00737251 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00737013 |
| SERINC5 | serine incorporator 5 | 0.0072655 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00721958 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00721436 |
| IL6ST | interleukin 6 signal transducer | 0.00719195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00718211 |
| AMT | aminomethyltransferase | 0.0071687 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00716258 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00715789 |
| ITGB4 | integrin, beta 4 | 0.00713881 |
| OPHN1 | oligophrenin 1 | 0.00712952 |
| GPX2 | glutathione peroxidase 2 | 0.00711176 |
| HAND2-AS1 | HAND2 antisense RNA 1 (head to head) | 0.00710763 |
| CAPN3 | calpain 3, (p94) | 0.00704864 |
| LAMC2 | laminin, gamma 2 | 0.00702636 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00702212 |
| KRT13 | keratin 13, type I | 0.00701521 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0070061 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00698051 |
| BCR | breakpoint cluster region | 0.00694094 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00694032 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00693504 |
| RNF167 | ring finger protein 167 | 0.0069097 |
| HDLBP | high density lipoprotein binding protein | 0.00690175 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00688931 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0068859 |
| NOP56 | NOP56 ribonucleoprotein | 0.00687724 |
| PCP4 | Purkinje cell protein 4 | 0.00685321 |
| SPRR3 | small proline-rich protein 3 | 0.00682258 |
| TRIOBP | TRIO and F-actin binding protein | 0.00681981 |
| PLCB4 | phospholipase C, beta 4 | 0.00681891 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00681755 |
| CST1 | cystatin SN | 0.00677695 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0067697 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00675984 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00674984 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00674824 |
| LAMA3 | laminin, alpha 3 | 0.00673503 |
| CHPT1 | choline phosphotransferase 1 | 0.00672526 |
| BAG3 | BCL2-associated athanogene 3 | 0.00672412 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00668427 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.00664334 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00663276 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00663026 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00659756 |
| RRAGD | Ras-related GTP binding D | 0.00657891 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00657654 |
| INAVA | innate immunity activator | 0.00657626 |
| CSTA | cystatin A (stefin A) | 0.00656314 |
| FKBP5 | FK506 binding protein 5 | 0.00655065 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00654195 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00654095 |
| ALB | albumin | 0.00653399 |
| MID1 | midline 1 | 0.00652862 |
| RNASET2 | ribonuclease T2 | 0.00652747 |
| GOLGB1 | golgin B1 | 0.00652631 |
| MLXIP | MLX interacting protein | 0.00652398 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00652271 |
| JUNB | jun B proto-oncogene | 0.00651254 |
| PTGES | prostaglandin E synthase | 0.00650805 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0064988 |
| NINL | ninein-like | 0.00649473 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00649155 |
| KRT81 | keratin 81, type II | 0.00647092 |
| DNMBP | dynamin binding protein | 0.006458 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00645507 |
| KLHL24 | kelch-like family member 24 | 0.00644723 |
| SELE | selectin E | 0.00644612 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00643289 |
| KRT6A | keratin 6A, type II | 0.00642688 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00642251 |
| MVP | major vault protein | 0.00639269 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00638306 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.00638018 |
| MEIS2 | Meis homeobox 2 | 0.00633925 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00632074 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00631905 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00631252 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00630587 |
| CFB | complement factor B | 0.00630461 |
| AFTPH | aftiphilin | 0.00628251 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0062812 |
| PHIP | pleckstrin homology domain interacting protein | 0.00627931 |
| BMP4 | bone morphogenetic protein 4 | 0.00626833 |
| GAB2 | GRB2-associated binding protein 2 | 0.00624987 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00623814 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0062359 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00623153 |
| PLTP | phospholipid transfer protein | 0.00620545 |
| LTF | lactotransferrin | 0.00619763 |
| PEG10 | paternally expressed 10 | 0.0061836 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.00618165 |
| PNMA8A | PNMA family member 8A | 0.0061793 |
| CERS6 | ceramide synthase 6 | 0.00616402 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 | 0.00614336 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00614328 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00614189 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0061416 |
| H1-0 | H1.0 linker histone | 0.00612719 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00612133 |
| CTSH | cathepsin H | 0.00609108 |
| BLNK | B-cell linker | 0.00608238 |
| TJP2 | tight junction protein 2 | 0.00607685 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00605536 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00605451 |
| VCAN | versican | 0.00603731 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.0060318 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0060057 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00600537 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00599614 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00599326 |
| HSPA12A | heat shock 70kDa protein 12A | 0.00598085 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00597443 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.00596839 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00596107 |
| POU4F1 | POU class 4 homeobox 1 | 0.00595895 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00594028 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00593904 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0059299 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00592949 |
| PEG3 | paternally expressed 3 | 0.00592772 |
| RHCG | Rh family, C glycoprotein | 0.00591967 |
| PSAP | prosaposin | 0.00591929 |
| CYTH1 | cytohesin 1 | 0.00590656 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00590258 |
| DIPK1A | divergent protein kinase domain 1A | 0.0058893 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 0.00588029 |
| CAPNS1 | calpain, small subunit 1 | 0.00587859 |
| NKX3-1 | NK3 homeobox 1 | 0.00587751 |
| OLFML3 | olfactomedin-like 3 | 0.00586167 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.0058592 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.00585654 |
| MEIS1 | Meis homeobox 1 | 0.00585495 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00585042 |
| LYST | lysosomal trafficking regulator | 0.00584502 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00584303 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00583483 |
| OFD1 | oral-facial-digital syndrome 1 | 0.00583261 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00583167 |
| RHOB | ras homolog family member B | 0.00583103 |
| CLTB | clathrin, light chain B | 0.0058286 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00582407 |
| PARD3 | par-3 family cell polarity regulator | 0.00581899 |
| XPC | xeroderma pigmentosum, complementation group C | 0.005813 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00580178 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00578974 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00578624 |
| COPS7A | COP9 signalosome subunit 7A | 0.00578186 |
| LAMA4 | laminin, alpha 4 | 0.00577644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.025149 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0202256 |
| HOPX | HOP homeobox | -0.0187617 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0180654 |
| CA2 | carbonic anhydrase II | -0.0153851 |
| TMSB15A | thymosin beta 15a | -0.0128824 |
| SRGN | serglycin | -0.0123526 |
| SPP1 | secreted phosphoprotein 1 | -0.011172 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.0109723 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0108221 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.0106434 |
| FST | follistatin | -0.0105092 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0104806 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0104143 |
| RPA3 | replication protein A3, 14kDa | -0.0103957 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.0103377 |
| EVI2A | ecotropic viral integration site 2A | -0.0103221 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0103009 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0100321 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00996411 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0099436 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00979943 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00973443 |
| LY96 | lymphocyte antigen 96 | -0.0097024 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00966636 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00955941 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00939393 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00936014 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00934924 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00934862 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00934674 |
| TMEM165 | transmembrane protein 165 | -0.00930347 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00917746 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00914718 |
| NNMT | nicotinamide N-methyltransferase | -0.00910834 |
| CRIP2 | cysteine-rich protein 2 | -0.00906549 |
| TEX30 | testis expressed 30 | -0.00901051 |
| COMMD8 | COMM domain containing 8 | -0.00900059 |
| EGR2 | early growth response 2 | -0.00895801 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00894295 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00872848 |
| CEL | carboxyl ester lipase | -0.00869796 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00868364 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00859685 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00856753 |
| DCK | deoxycytidine kinase | -0.00856655 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00855755 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00853193 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00851982 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00845592 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00839605 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00834342 |
| WDR7 | WD repeat domain 7 | -0.0082833 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00828226 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00825541 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00818517 |
| S100A4 | S100 calcium binding protein A4 | -0.00806722 |
| TSPAN4 | tetraspanin 4 | -0.00806521 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.00803323 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.008027 |
| PRDX4 | peroxiredoxin 4 | -0.00801178 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00799042 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.0079598 |
| RTN2 | reticulon 2 | -0.00794551 |
| GAS1 | growth arrest-specific 1 | -0.00793039 |
| CD52 | CD52 molecule | -0.00789761 |
| TGFB1 | transforming growth factor, beta 1 | -0.00785926 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00777691 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00776785 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00774229 |
| PCLAF | PCNA clamp associated factor | -0.00771863 |
| ZG16 | zymogen granule protein 16 | -0.00770944 |
| TFEC | transcription factor EC | -0.00769673 |
| TMEM126B | transmembrane protein 126B | -0.00768742 |
| SIKE1 | suppressor of IKBKE 1 | -0.00766394 |
| TSPAN13 | tetraspanin 13 | -0.00765196 |
| MMP9 | matrix metallopeptidase 9 | -0.00761596 |
| ASF1A | anti-silencing function 1A histone chaperone | -0.0076131 |
| COMP | cartilage oligomeric matrix protein | -0.00761013 |
| CALR | calreticulin | -0.00760736 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00759088 |
| TMEM70 | transmembrane protein 70 | -0.00757573 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00752968 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00752078 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -0.0075081 |
| SEH1L | SEH1-like (S. cerevisiae) | -0.00746238 |
| WTAP | Wilms tumor 1 associated protein | -0.00745198 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00740913 |
| HTRA1 | HtrA serine peptidase 1 | -0.00737335 |
| ATF1 | activating transcription factor 1 | -0.00735797 |
| LRRC15 | leucine rich repeat containing 15 | -0.00733799 |
| LRRC17 | leucine rich repeat containing 17 | -0.00733763 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00731634 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00728687 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.007251 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00724778 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00724046 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | -0.00722478 |
| EMP3 | epithelial membrane protein 3 | -0.00716853 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00715357 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.00714488 |
| TOB1 | transducer of ERBB2, 1 | -0.00714411 |
| LST1 | leukocyte specific transcript 1 | -0.00711137 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00706175 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00703212 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.007009 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00699496 |
| TIPRL | TOR signaling pathway regulator | -0.00694785 |
| MDFIC | MyoD family inhibitor domain containing | -0.00693038 |
| APOC1 | apolipoprotein C-I | -0.006913 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00690488 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00688926 |
| PGRMC2 | progesterone receptor membrane component 2 | -0.00688558 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | -0.0068285 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00682086 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00681484 |
| LIN7C | lin-7 homolog C (C. elegans) | -0.00680066 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00680065 |
| TAGLN | transgelin | -0.00679279 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00676036 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00675188 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00675123 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00673852 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.0067173 |
| NPR3 | natriuretic peptide receptor 3 | -0.00668378 |
| CYTL1 | cytokine-like 1 | -0.00666995 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00666227 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00666026 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00666004 |
| DGKZ | diacylglycerol kinase, zeta | -0.00661389 |
| CDK1 | cyclin-dependent kinase 1 | -0.00660883 |
| CTSD | cathepsin D | -0.00660723 |
| CD320 | CD320 molecule | -0.00657272 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00657167 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00654272 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00653526 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00653239 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00651556 |
| TMEM38B | transmembrane protein 38B | -0.00649943 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00649697 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00649129 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.00648132 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00647844 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00644572 |
| SMYD3 | SET and MYND domain containing 3 | -0.00641448 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00641206 |
| TMX1 | thioredoxin-related transmembrane protein 1 | -0.00641205 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00639928 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00638381 |
| THAP12 | THAP domain containing 12 | -0.00638209 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N | -0.0063795 |
| PAQR3 | progestin and adipoQ receptor family member III | -0.00637459 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00636997 |
| CDCA4 | cell division cycle associated 4 | -0.00636079 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.0063581 |
| TSPAN12 | tetraspanin 12 | -0.0063476 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00634215 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00633533 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00632457 |
| ANKRD46 | ankyrin repeat domain 46 | -0.00631092 |
| CCND2 | cyclin D2 | -0.00630278 |
| WDR61 | WD repeat domain 61 | -0.00630167 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00629857 |
| C4BPA | complement component 4 binding protein, alpha | -0.00629597 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00629304 |
| TMEM14A | transmembrane protein 14A | -0.00628794 |
| H2AZ1 | H2A.Z variant histone 1 | -0.00628504 |
| NINJ2 | ninjurin 2 | -0.00625666 |
| HMGB3 | high mobility group box 3 | -0.00625596 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.0062244 |
| COPS4 | COP9 signalosome subunit 4 | -0.00615956 |
| MED7 | mediator complex subunit 7 | -0.00615462 |
| TK1 | thymidine kinase 1, soluble | -0.00615198 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) | -0.00613896 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00612333 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00611704 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00611657 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00609641 |
| FASN | fatty acid synthase | -0.00608988 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.00608163 |
| LRRC40 | leucine rich repeat containing 40 | -0.00607445 |
| BDNF | brain-derived neurotrophic factor | -0.00605592 |
| CBR4 | carbonyl reductase 4 | -0.00603708 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00602177 |
| STK17A | serine/threonine kinase 17a | -0.00601927 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00601261 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00600911 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00599987 |
| COL10A1 | collagen, type X, alpha 1 | -0.00599402 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | -0.0059879 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00597344 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00596693 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0059483 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00594228 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00593683 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00592911 |
| CTSS | cathepsin S | -0.00592556 |
| COMMD10 | COMM domain containing 10 | -0.00592539 |
| SLFN12 | schlafen family member 12 | -0.00592075 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00591954 |
| RMI1 | RecQ mediated genome instability 1 | -0.00591705 |
| FPR3 | formyl peptide receptor 3 | -0.00591229 |
| GMFB | glia maturation factor, beta | -0.00590098 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00588863 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00587832 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00587514 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.0058696 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | -0.00585992 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00585789 |
| CRYZ | crystallin, zeta (quinone reductase) | -0.00585453 |
| PSPH | phosphoserine phosphatase | -0.00584246 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00584157 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00583965 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.0058324 |
| MRPL11 | mitochondrial ribosomal protein L11 | -0.00582355 |
| C1ORF174 | chromosome 1 open reading frame 174 | -0.00579564 |
| TMEM14B | transmembrane protein 14B | -0.0057941 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.005777 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.00574328 |
| SRI | sorcin | -0.00571831 |
| GLRX2 | glutaredoxin 2 | -0.00570283 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00570052 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.00568515 |
| MTCH2 | mitochondrial carrier 2 | -0.00568345 |
| NOTCH2NL | notch 2 N-terminal like | -0.00566522 |
| DCTPP1 | dCTP pyrophosphatase 1 | -0.0056561 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00565421 |
| CBX3 | chromobox homolog 3 | -0.00565231 |
| CDH13 | cadherin 13 | -0.00565152 |
| NRBF2 | nuclear receptor binding factor 2 | -0.00564861 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00563335 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00563319 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00562712 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00560327 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00559992 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00559921 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00558633 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00558281 |
| MT3 | metallothionein 3 | -0.00557918 |
| OIP5 | Opa interacting protein 5 | -0.00557683 |
| BSG | basigin (Ok blood group) | -0.00555264 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00554543 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -0.00551685 |
| FRZB | frizzled-related protein | -0.00551668 |
| TXNL1 | thioredoxin-like 1 | -0.00551348 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.0055132 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) | -0.00550781 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.00550561 |
| FSTL1 | follistatin-like 1 | -0.00550041 |
| RPL39L | ribosomal protein L39-like | -0.00549973 |
