| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | acetylcholinesterase (Yt blood group)|Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 43) |
| External Link | https://ncbi.nlm.nih.gov/gene/43 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the ACHE gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0145464 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0111087 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0110613 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0108955 |
| LY96 | lymphocyte antigen 96 | 0.010644 |
| KRT14 | keratin 14, type I | 0.0106419 |
| FCGBP | Fc fragment of IgG binding protein | 0.010504 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0100056 |
| HTRA1 | HtrA serine peptidase 1 | 0.00993254 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00982295 |
| ADIRF | adipogenesis regulatory factor | 0.00962451 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00937613 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00918572 |
| HOPX | HOP homeobox | 0.00896833 |
| CA12 | carbonic anhydrase XII | 0.00893156 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00891655 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00891645 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0087576 |
| GPX1 | glutathione peroxidase 1 | 0.00855085 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00851371 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00850912 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00845392 |
| AOC1 | amine oxidase, copper containing 1 | 0.00844633 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00823797 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00812017 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00803329 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.00777006 |
| ASS1 | argininosuccinate synthase 1 | 0.00773104 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00760649 |
| SNAI2 | snail family zinc finger 2 | 0.00757578 |
| UPP1 | uridine phosphorylase 1 | 0.00751559 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00738513 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00729536 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00728076 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00722343 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00722233 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00718648 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00717373 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | 0.0070979 |
| C1QA | complement component 1, q subcomponent, A chain | 0.007086 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00702559 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00702283 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00700196 |
| CRYAB | crystallin, alpha B | 0.00697594 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00696923 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00694613 |
| LCN2 | lipocalin 2 | 0.00692665 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00682801 |
| ANXA4 | annexin A4 | 0.00675945 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.00673877 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00673356 |
| RPS27L | ribosomal protein S27-like | 0.0067082 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00668683 |
| SST | somatostatin | 0.00667891 |
| ZG16 | zymogen granule protein 16 | 0.00664881 |
| AREG | amphiregulin | 0.00663698 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00662926 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.0065984 |
| XIC | X chromosome inactivation center | 0.00659039 |
| GPR137B | G protein-coupled receptor 137B | 0.00653818 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00652261 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00647708 |
| S100A10 | S100 calcium binding protein A10 | 0.00646474 |
| CLCA4 | chloride channel accessory 4 | 0.00642504 |
| CTSD | cathepsin D | 0.00642278 |
| PLK1 | polo-like kinase 1 | 0.00642185 |
| TAGLN2 | transgelin 2 | 0.00640191 |
| GUK1 | guanylate kinase 1 | 0.00640188 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00639334 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00638791 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00637303 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00635672 |
| SRI | sorcin | 0.00635603 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00628643 |
| SSR4 | signal sequence receptor, delta | 0.00626767 |
| KRT13 | keratin 13, type I | 0.00626078 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00624148 |
| DCN | decorin | 0.00623127 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00621965 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00620849 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00620441 |
| IFI35 | interferon-induced protein 35 | 0.00620258 |
| AK1 | adenylate kinase 1 | 0.00619206 |
| NNMT | nicotinamide N-methyltransferase | 0.00618289 |
| MT1X | metallothionein 1X | 0.00617872 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00615451 |
| MXRA7 | matrix-remodelling associated 7 | 0.00613532 |
| CLCA1 | chloride channel accessory 1 | 0.00612658 |
| C1S | complement component 1, s subcomponent | 0.00611125 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.0061074 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00608329 |
| RBM34 | RNA binding motif protein 34 | 0.00607483 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00607417 |
| C1R | complement component 1, r subcomponent | 0.00601687 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00600961 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00598686 |
| KLK10 | kallikrein-related peptidase 10 | 0.00597962 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 0.0059674 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00593993 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00586392 |
| MEOX2 | mesenchyme homeobox 2 | 0.00585843 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00585831 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00585339 |
| ATF3 | activating transcription factor 3 | 0.00582859 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00582211 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00576423 |
| RGS1 | regulator of G-protein signaling 1 | 0.00576361 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.00575612 |
| IL18 | interleukin 18 | 0.00575323 |
| ATP5MF | ATP synthase membrane subunit f | 0.00570606 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00569805 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00569328 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00566227 |
| NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 0.00566031 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00564819 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00564468 |
| MRPS12 | mitochondrial ribosomal protein S12 | 0.00563206 |
| UBE2M | ubiquitin-conjugating enzyme E2M | 0.00559881 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00556826 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase | 0.00556529 |
| MIR22HG | MIR22 host gene | 0.00556459 |
| IL1RN | interleukin 1 receptor antagonist | 0.00555181 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00553364 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00553102 |
| WTAP | Wilms tumor 1 associated protein | 0.00552457 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.00552447 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 0.005516 |
| AK4 | adenylate kinase 4 | 0.00549983 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00547833 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00546081 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0054553 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00544476 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00543694 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00543511 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00543153 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00542909 |
| LYRM4 | LYR motif containing 4 | 0.00542123 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.00541587 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00541377 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00540478 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00540364 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00539547 |
| WDR7 | WD repeat domain 7 | 0.00539455 |
| TGFB3 | transforming growth factor, beta 3 | 0.00538917 |
| NUTF2 | nuclear transport factor 2 | 0.00538912 |
| PFDN4 | prefoldin subunit 4 | 0.00537025 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0053617 |
| DEFB1 | defensin, beta 1 | 0.00535845 |
| CFB | complement factor B | 0.00535042 |
| IFI44L | interferon-induced protein 44-like | 0.00534695 |
| SFN | stratifin | 0.00532822 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00532727 |
| STK17A | serine/threonine kinase 17a | 0.00532406 |
| TOX | thymocyte selection-associated high mobility group box | 0.0052688 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.00526714 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00524874 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00524601 |
| HMOX1 | heme oxygenase 1 | 0.00524057 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00524044 |
| FBXO11 | F-box protein 11 | 0.0052327 |
| OGN | osteoglycin | 0.00522041 |
| SEC24A | SEC24 family member A | 0.00521433 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.0052133 |
| REEP5 | receptor accessory protein 5 | 0.00519171 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00515931 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00515576 |
| CLTB | clathrin, light chain B | 0.00515157 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | 0.00513183 |
| RGCC | regulator of cell cycle | 0.00512373 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00512101 |
| SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 0.0050914 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00507414 |
| PLVAP | plasmalemma vesicle associated protein | 0.00507133 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0050701 |
| KLF10 | Kruppel-like factor 10 | 0.00505789 |
| RFK | riboflavin kinase | 0.0050341 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00503047 |
| CA2 | carbonic anhydrase II | 0.0050178 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00500463 |
| COA3 | cytochrome c oxidase assembly factor 3 | 0.00500118 |
| STX8 | syntaxin 8 | 0.00499767 |
| TXLNA | taxilin alpha | 0.00499524 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00499404 |
| BSG | basigin (Ok blood group) | 0.0049843 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00498151 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00498045 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00497784 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00497015 |
| OPTN | optineurin | 0.00496984 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00496234 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00496146 |
| PALLD | palladin, cytoskeletal associated protein | 0.00494938 |
| DSTN | destrin (actin depolymerizing factor) | 0.00494643 |
| CD52 | CD52 molecule | 0.00493887 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00493366 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00492454 |
| STAB1 | stabilin 1 | 0.0049104 |
| IER5 | immediate early response 5 | 0.00491034 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.00489933 |
| SLN | sarcolipin | 0.00489436 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00488691 |
| XAF1 | XIAP associated factor 1 | 0.00488001 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.0048545 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00485436 |
| THBS1 | thrombospondin 1 | 0.00485138 |
| PDZD2 | PDZ domain containing 2 | 0.00484954 |
| EGR2 | early growth response 2 | 0.00484314 |
| CA4 | carbonic anhydrase IV | 0.00484189 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00483256 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.0048271 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00482463 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00480578 |
| NOTCH1 | notch 1 | 0.00479965 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.00477708 |
| WT1 | Wilms tumor 1 | 0.00477006 |
| TSPO | translocator protein (18kDa) | 0.00477001 |
| PRDX4 | peroxiredoxin 4 | 0.00476867 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.00476685 |
| CD93 | CD93 molecule | 0.00476684 |
| JAM3 | junctional adhesion molecule 3 | 0.00474972 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.00474074 |
| PTN | pleiotrophin | 0.00472268 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00471751 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00470914 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.00470714 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00469387 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 0.00469262 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00468865 |
| DUSP5 | dual specificity phosphatase 5 | 0.00468704 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00467539 |
| E2F2 | E2F transcription factor 2 | 0.00467292 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00466471 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00465763 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00465593 |
| GCG | glucagon | 0.00464624 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00464385 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | 0.00464248 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00463527 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00463463 |
| RPL36 | ribosomal protein L36 | 0.00462805 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.0046279 |
| IL6R | interleukin 6 receptor | 0.00462434 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00462023 |
| MRPS18A | mitochondrial ribosomal protein S18A | 0.00461605 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00461562 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00460153 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00460001 |
| MGST3 | microsomal glutathione S-transferase 3 | 0.00459718 |
| GM2A | GM2 ganglioside activator | 0.00459374 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00458735 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0138787 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0136502 |
| EPCAM | epithelial cell adhesion molecule | -0.0115722 |
| BMP4 | bone morphogenetic protein 4 | -0.0106118 |
| CADM1 | cell adhesion molecule 1 | -0.0101453 |
| LYZ | lysozyme | -0.00994294 |
| MAP7 | microtubule-associated protein 7 | -0.00832049 |
| APOA2 | apolipoprotein A-II | -0.00796667 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00788732 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.00778036 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0077592 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00767233 |
| PNN | pinin, desmosome associated protein | -0.00760818 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00747521 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00745308 |
| HBB | hemoglobin, beta | -0.00730958 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00720915 |
| PCP4 | Purkinje cell protein 4 | -0.00706702 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00705943 |
| SRPRA | SRP receptor subunit alpha | -0.00703902 |
| VLDLR | very low density lipoprotein receptor | -0.00702123 |
| PROM1 | prominin 1 | -0.00698466 |
| DCLK1 | doublecortin-like kinase 1 | -0.00696493 |
| IPO13 | importin 13 | -0.00696015 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00694803 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.0068686 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0068522 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00683527 |
| STC1 | stanniocalcin 1 | -0.00680165 |
| TSPYL5 | TSPY-like 5 | -0.00657223 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0065381 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00651705 |
| TNC | tenascin C | -0.00651661 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00649517 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00640379 |
| AHSG | alpha-2-HS-glycoprotein | -0.00639045 |
| CTBP2 | C-terminal binding protein 2 | -0.00638566 |
| EXPH5 | exophilin 5 | -0.0063105 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00627096 |
| KAZN | kazrin, periplakin interacting protein | -0.00626734 |
| SVIL | supervillin | -0.00624633 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00622048 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00613429 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00603356 |
| POSTN | periostin, osteoblast specific factor | -0.00595484 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00595294 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00590922 |
| PTK2 | protein tyrosine kinase 2 | -0.00588896 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00586758 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00583973 |
| NEBL | nebulette | -0.00583885 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00579667 |
| PCDH9 | protocadherin 9 | -0.00578606 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00577489 |
| ARGLU1 | arginine and glutamate rich 1 | -0.00576641 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00572055 |
| LTF | lactotransferrin | -0.00571744 |
| RNF43 | ring finger protein 43 | -0.00569084 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00567789 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.00566748 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00564294 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00562748 |
| FGF13 | fibroblast growth factor 13 | -0.00562467 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00560475 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.00560036 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.00559705 |
| KIF14 | kinesin family member 14 | -0.00557766 |
| WWOX | WW domain containing oxidoreductase | -0.00555903 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.00554907 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00553907 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00546684 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.00544723 |
| PKP4 | plakophilin 4 | -0.00544583 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00539909 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00537736 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00535349 |
| PER3 | period circadian clock 3 | -0.00534905 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00534693 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.00533788 |
| RAB25 | RAB25, member RAS oncogene family | -0.00533688 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00533027 |
| SERINC5 | serine incorporator 5 | -0.00531831 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00530547 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00529494 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00529144 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.00529053 |
| MAL | mal, T-cell differentiation protein | -0.00528367 |
| MLEC | malectin | -0.00528326 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | -0.00527726 |
| APOA1 | apolipoprotein A-I | -0.00524769 |
| DMD | dystrophin | -0.00523092 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00522925 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.00520825 |
| SNX1 | sorting nexin 1 | -0.00519662 |
| PPL | periplakin | -0.00519003 |
| APOD | apolipoprotein D | -0.00518752 |
| FZD6 | frizzled class receptor 6 | -0.00517054 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00516644 |
| ADIPOR2 | adiponectin receptor 2 | -0.00516533 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00516346 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00515292 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00511784 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.00511534 |
| MYO5C | myosin VC | -0.00509686 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.00507965 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | -0.00507801 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00506424 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00505776 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00504786 |
| DHFR | dihydrofolate reductase | -0.00504089 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00502595 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0050206 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | -0.00501133 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00500964 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00500279 |
| GDF15 | growth differentiation factor 15 | -0.00500179 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00500041 |
| GPC3 | glypican 3 | -0.00499376 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00498918 |
| HOMER2 | homer scaffolding protein 2 | -0.00497074 |
| IRS1 | insulin receptor substrate 1 | -0.00496097 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00495592 |
| SFTPC | surfactant protein C | -0.00492889 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.00492118 |
| ARG2 | arginase 2 | -0.00491395 |
| H1-0 | H1.0 linker histone | -0.00490583 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00490419 |
| GRHL2 | grainyhead-like 2 (Drosophila) | -0.00489497 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00487536 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | -0.00487168 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00484492 |
| TFDP1 | transcription factor Dp-1 | -0.00483962 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 | -0.00482274 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.00481774 |
| PSPC1 | paraspeckle component 1 | -0.00481725 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00480888 |
| FKBP5 | FK506 binding protein 5 | -0.00479647 |
| DMXL2 | Dmx-like 2 | -0.0047935 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00479344 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00478622 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | -0.00477943 |
| FADS1 | fatty acid desaturase 1 | -0.00476572 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -0.00475938 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00473023 |
| RAPSN | receptor-associated protein of the synapse | -0.0047194 |
| MARCO | macrophage receptor with collagenous structure | -0.00471915 |
| MSH2 | mutS homolog 2 | -0.00469614 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00469117 |
| SIM2 | single-minded family bHLH transcription factor 2 | -0.00467782 |
| CLDN3 | claudin 3 | -0.00467479 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00466484 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00465995 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00465879 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.004649 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.00464515 |
| AZIN1 | antizyme inhibitor 1 | -0.0046403 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0046341 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00462522 |
| ANXA5 | annexin A5 | -0.00462372 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00461622 |
| PXN | paxillin | -0.00460493 |
| MELK | maternal embryonic leucine zipper kinase | -0.00458547 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00456422 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00455047 |
| RSRP1 | arginine/serine-rich protein 1 | -0.00455005 |
| NKTR | natural killer cell triggering receptor | -0.00454823 |
| CS | citrate synthase | -0.00453938 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00452615 |
| GLUL | glutamate-ammonia ligase | -0.00451833 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00451217 |
| RAB20 | RAB20, member RAS oncogene family | -0.00451098 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.00450914 |
| INSR | insulin receptor | -0.00450171 |
| RAB3B | RAB3B, member RAS oncogene family | -0.00448071 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.00447689 |
| SEPTIN2 | septin 2 | -0.00447535 |
| MANSC1 | MANSC domain containing 1 | -0.00447443 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00445581 |
| NCALD | neurocalcin delta | -0.00442831 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.00442293 |
| PLCB4 | phospholipase C, beta 4 | -0.00440881 |
| KYNU | kynureninase | -0.00440555 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00439876 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | -0.00439389 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00438694 |
| LY75 | lymphocyte antigen 75 | -0.00438467 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00436977 |
| PHIP | pleckstrin homology domain interacting protein | -0.00436975 |
| NPY | neuropeptide Y | -0.00436674 |
| CCKBR | cholecystokinin B receptor | -0.00436663 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00436217 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00434284 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00433488 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.00433344 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00432667 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.0043263 |
| CERS6 | ceramide synthase 6 | -0.00432042 |
| SUOX | sulfite oxidase | -0.00432013 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.0043188 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.00431462 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00430807 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00429431 |
| SCRIB | scribbled planar cell polarity protein | -0.00429136 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00428214 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00428031 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00427963 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00427068 |
| MEIS2 | Meis homeobox 2 | -0.00426546 |
| CLDN1 | claudin 1 | -0.00426198 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.00426077 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00424598 |
| TIMELESS | timeless circadian clock | -0.00424395 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00424047 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00423935 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.00423127 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00422132 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00421597 |
| KIF15 | kinesin family member 15 | -0.00421485 |
| LPIN1 | lipin 1 | -0.00420507 |
| RDX | radixin | -0.00420222 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00419562 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.00419135 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | -0.00418787 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00418729 |
| E2F8 | E2F transcription factor 8 | -0.00418067 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00416777 |
| OR51E2 | olfactory receptor, family 51, subfamily E, member 2 | -0.00416563 |
| MACROH2A1 | macroH2A.1 histone | -0.00415894 |
| ALB | albumin | -0.00415763 |
| FRY | furry homolog (Drosophila) | -0.00415544 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00415492 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.00415422 |
| IL27RA | interleukin 27 receptor, alpha | -0.00415082 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00414313 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00411052 |
| IL6ST | interleukin 6 signal transducer | -0.00410838 |
| NUCLEOLIN | nucleolin multifunctional protein | -0.00409933 |
| GPC4 | glypican 4 | -0.00409912 |
| RGN | regucalcin | -0.00407944 |
| TMC6 | transmembrane channel-like 6 | -0.00406832 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00404654 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.00404528 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.00403648 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00403358 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00403187 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00403159 |
| PAIP2B | poly(A) binding protein interacting protein 2B | -0.00403149 |
| ADCY9 | adenylate cyclase 9 | -0.00402981 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00402268 |
| MGAM | maltase-glucoamylase | -0.00402035 |
