ACTN4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description actinin, alpha 4|Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 81)
Similar Terms
Downloads & Tools

Genes

406 genes differentially expressed following the ACTN4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
BTN1A1 butyrophilin, subfamily 1, member A1 2.93812
FIMP1 fertilization-influencing membrane protein 1 2.93812
MMP20 matrix metallopeptidase 20 2.93812
BCO2 beta-carotene oxygenase 2 2.93812
DAW1 dynein assembly factor with WDR repeat domains 1 2.93812
CHRM1 cholinergic receptor, muscarinic 1 2.93812
CLEC5A C-type lectin domain family 5, member A 2.93812
TTLL2 tubulin tyrosine ligase-like family member 2 2.93812
GRAP2 GRB2-related adaptor protein 2 2.93812
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.93812
PDZRN4 PDZ domain containing ring finger 4 2.93812
BHLHE40 basic helix-loop-helix family, member e40 2.93812
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.93812
IRF7 interferon regulatory factor 7 2.93812
CIITA class II, major histocompatibility complex, transactivator 2.93812
LOC124900192 uncharacterized LOC124900192 2.93812
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.93812
DUSP9 dual specificity phosphatase 9 2.93812
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 2.93812
RTP1 receptor (chemosensory) transporter protein 1 2.93812
ETV3L ets variant 3-like 2.93812
FGF4 fibroblast growth factor 4 2.93812
PGM5 phosphoglucomutase 5 2.93812
PSD2 pleckstrin and Sec7 domain containing 2 2.93812
TUBB8 tubulin, beta 8 class VIII 2.90997
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.90997
AKR1C2 aldo-keto reductase family 1, member C2 2.90997
WFDC13 WAP four-disulfide core domain 13 2.90997
ZNF181 zinc finger protein 181 2.90997
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.90997
SIGLEC5 sialic acid binding Ig-like lectin 5 2.90997
CEP295NL CEP295 N-terminal like 2.90997
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 2.90997
SIRPB2 signal-regulatory protein beta 2 2.90997
AFM afamin 2.90997
SKOR2 SKI family transcriptional corepressor 2 2.90997
TMEM100 transmembrane protein 100 2.90997
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.90997
CD34 CD34 molecule 2.90997
CSTL1 cystatin-like 1 2.90997
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.90997
FAM81B family with sequence similarity 81, member B 2.90997
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.90997
NPIPA8 nuclear pore complex interacting protein family, member A8 2.90997
LRRC61 leucine rich repeat containing 61 2.90997
CRYGA crystallin, gamma A 2.90997
ASCL5 achaete-scute family bHLH transcription factor 5 2.90997
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.90997
IL2RB interleukin 2 receptor, beta 2.90997
LOC105378220 macrophage receptor MARCO-like 2.90997
LGALS2 lectin, galactoside-binding, soluble, 2 2.90997
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.90997
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.90997
C8ORF74 chromosome 8 open reading frame 74 2.90997
POSTN periostin, osteoblast specific factor 2.90997
FAM161B family with sequence similarity 161, member B 2.90997
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 2.90997
MROH2B maestro heat-like repeat family member 2B 2.90997
UBA7 ubiquitin-like modifier activating enzyme 7 2.90997
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 2.90997
SLC10A5 solute carrier family 10, member 5 2.90997
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.90997
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.90997
ZBTB5 zinc finger and BTB domain containing 5 2.90997
AVPR1B arginine vasopressin receptor 1B 2.90997
HBG2 hemoglobin, gamma G 2.90997
ADGRG6 adhesion G protein-coupled receptor G6 2.90997
RD3 retinal degeneration 3 2.90997
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.90997
TSPAN8 tetraspanin 8 2.90997
CNOT10 CCR4-NOT transcription complex, subunit 10 2.90997
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.90997
KL klotho 2.90997
IL16 interleukin 16 2.90997
MCHR1 melanin-concentrating hormone receptor 1 2.90997
SEPTIN14 septin 14 2.90997
STING1 stimulator of interferon response cGAMP interactor 1 2.90997
CIMIP7 ciliary microtubule inner protein 7 2.90997
STRIT1 small transmembrane regulator of ion transport 1 2.90997
H4C12 H4 clustered histone 12 2.90997
ACP7 acid phosphatase 7, tartrate resistant (putative) 2.90997
LHFPL7 LHFPL tetraspan subfamily member 7 2.90997
LY6L lymphocyte antigen 6 family member L 2.90997
RTL5 retrotransposon Gag like 5 2.90997
CBLIF cobalamin binding intrinsic factor 2.90997
PLAAT2 phospholipase A and acyltransferase 2 2.90997
LBHD2 LBH domain containing 2 2.90997
IL1RN interleukin 1 receptor antagonist 2.90997
TACR2 tachykinin receptor 2 2.90997
MYH13 myosin, heavy chain 13, skeletal muscle 2.90997
RAB44 RAB44, member RAS oncogene family 2.90997
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.90997
GJA4 gap junction protein, alpha 4, 37kDa 2.90997
TMPRSS11D transmembrane protease, serine 11D 2.90997
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.90997
SIGLECL1 SIGLEC family like 1 2.90997
TRMT61B tRNA methyltransferase 61B 2.90997
HPCAL4 hippocalcin like 4 2.90997
IZUMO3 IZUMO family member 3 2.90997
CELF3 CUGBP, Elav-like family member 3 2.90997
WDR38 WD repeat domain 38 2.90997
PCDHB13 protocadherin beta 13 2.90997
CLDN9 claudin 9 2.90997
TFEC transcription factor EC 2.90997
IL5 interleukin 5 2.90997
SIM2 single-minded family bHLH transcription factor 2 2.90997
GOLGA7B golgin A7 family, member B 2.90997
CXCL16 chemokine (C-X-C motif) ligand 16 2.90997
TMCO2 transmembrane and coiled-coil domains 2 2.90997
MSX1 msh homeobox 1 2.90997
TMEM235 transmembrane protein 235 2.90997
AXDND1 axonemal dynein light chain domain containing 1 2.90997
CCR6 chemokine (C-C motif) receptor 6 2.90997
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.90997
TBC1D10C TBC1 domain family, member 10C 2.90997
ZCCHC12 zinc finger, CCHC domain containing 12 2.90997
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.90997
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.90997
CATIP ciliogenesis associated TTC17 interacting protein 2.90997
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.90997
ERMN ermin, ERM-like protein 2.90997
FBXO40 F-box protein 40 2.90997
MFSD6L major facilitator superfamily domain containing 6-like 2.90997
TCF21 transcription factor 21 2.90997
TINAG tubulointerstitial nephritis antigen 2.90997
FGG fibrinogen gamma chain 2.90997
CFAP47 cilia and flagella associated protein 47 2.90997
AICDA activation-induced cytidine deaminase 2.90997
LRRC3 leucine rich repeat containing 3 2.90997
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.90997
ANKRD33 ankyrin repeat domain 33 2.90997
LPAR5 lysophosphatidic acid receptor 5 2.90997
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.90997
SEC14L3 SEC14-like 3 (S. cerevisiae) 2.90997
LRRC43 leucine rich repeat containing 43 2.90997
BPIFB1 BPI fold containing family B, member 1 2.90997
BPIFB4 BPI fold containing family B, member 4 2.90997
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.90997
IL21R interleukin 21 receptor 2.90997
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.90997
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.90997
C16ORF78 chromosome 16 open reading frame 78 2.90997
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 2.90997
POU6F2 POU class 6 homeobox 2 2.90997
MAB21L1 mab-21-like 1 (C. elegans) 2.90997
CTAGE4 CTAGE family, member 4 2.90997
ZDHHC11B zinc finger, DHHC-type containing 11B 2.90997
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.90997
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.90997
RGS18 regulator of G-protein signaling 18 2.90997
ALOXE3 arachidonate lipoxygenase 3 2.90997
IL19 interleukin 19 2.90997
STMND1 stathmin domain containing 1 2.90997
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 2.90997
MSLN mesothelin 2.90997
HPGDS hematopoietic prostaglandin D synthase 2.90997
THEM5 thioesterase superfamily member 5 2.90997
ARGFX arginine-fifty homeobox 2.90997
ARHGAP40 Rho GTPase activating protein 40 2.90997
PCDHAC2 protocadherin alpha subfamily C, 2 2.90997
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 2.90997
CLCNKB chloride channel, voltage-sensitive Kb 2.90997
ABLIM3 actin binding LIM protein family, member 3 2.90997
SDSL serine dehydratase-like 2.90997
LMX1A LIM homeobox transcription factor 1, alpha 2.90997
BCL2A1 BCL2-related protein A1 2.90997
TAS2R43 taste receptor, type 2, member 43 2.90997
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.90997
GOLGA8N golgin A8 family, member N 2.90997
ANXA8 annexin A8 2.90997
C22ORF31 chromosome 22 open reading frame 31 2.90997
XCR1 chemokine (C motif) receptor 1 2.90997
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.90997
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.90997
DMRTC1 DMRT-like family C1 2.90997
PRAP1 proline-rich acidic protein 1 2.90997
CPZ carboxypeptidase Z 2.90997
CD8B CD8b molecule 2.90997
ZBED6 zinc finger, BED-type containing 6 2.90997
AQP1 aquaporin 1 (Colton blood group) 2.90997
SIGLEC15 sialic acid binding Ig-like lectin 15 2.90997
DMRT1 doublesex and mab-3 related transcription factor 1 2.90997
POU3F2 POU class 3 homeobox 2 2.90997
NT5C1B 5'-nucleotidase, cytosolic IB 2.90997
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 2.90997
REN renin 2.90997
NMBR neuromedin B receptor 2.90997
REEP1 receptor accessory protein 1 2.90997
NKX6-2 NK6 homeobox 2 2.90997
POMT1 protein-O-mannosyltransferase 1 2.90997
PSG3 pregnancy specific beta-1-glycoprotein 3 2.90997
CGA glycoprotein hormones, alpha polypeptide 2.90997
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 2.87924
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.86911
NDRG4 NDRG family member 4 2.86423
AQP5 aquaporin 5 2.86423
NALCN sodium leak channel, non selective 2.86423
DPPA3 developmental pluripotency associated 3 2.86423
TFRC transferrin receptor 2.73973
DCPH1 damage control phosphatase 1 2.72458
YPEL4 yippee-like 4 (Drosophila) 2.6659
CMTR1 cap methyltransferase 1 2.63783
UBOX5 U-box domain containing 5 2.61311
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.59259
EXOC3 exocyst complex component 3 2.59195
ISM1 isthmin 1, angiogenesis inhibitor 2.59195
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.5779
SOX13 SRY (sex determining region Y)-box 13 2.57066
CCDC148 coiled-coil domain containing 148 2.54272
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.5299
PROSER1 proline and serine rich 1 2.52259
ARMC9 armadillo repeat containing 9 2.50381
MSN moesin 2.49925
MRPL22 mitochondrial ribosomal protein L22 2.49354
ACOX2 acyl-CoA oxidase 2, branched chain 2.49165
FAM151A family with sequence similarity 151, member A 2.49165
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 2.49061
OPA1 optic atrophy 1 (autosomal dominant) 2.49061
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 2.49061
PCDHAC1 protocadherin alpha subfamily C, 1 2.48738
NCAPH2 non-SMC condensin II complex, subunit H2 2.47504
SHROOM1 shroom family member 1 2.47242
OPRL1 opiate receptor-like 1 2.45129
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.45129
DAGLA diacylglycerol lipase, alpha 2.41524
C8ORF82 chromosome 8 open reading frame 82 2.41524
XKR5 XK, Kell blood group complex subunit-related family, member 5 2.3667
TLCD4 TLC domain containing 4 2.3667
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.36085
XRRA1 X-ray radiation resistance associated 1 2.34568
UCMA upper zone of growth plate and cartilage matrix associated 2.32006
LRRN1 leucine rich repeat neuronal 1 2.32006
PNP purine nucleoside phosphorylase 2.32006
SRSF11 serine/arginine-rich splicing factor 11 2.29082
PPP6R3 protein phosphatase 6, regulatory subunit 3 2.26582
ZNF141 zinc finger protein 141 2.25808
PGM2 phosphoglucomutase 2 2.24603
ELL2 elongation factor, RNA polymerase II, 2 2.23026
ZNF623 zinc finger protein 623 2.19765
TET2 tet methylcytosine dioxygenase 2 2.19765
BRPF3 bromodomain and PHD finger containing, 3 2.1857
ZNF813 zinc finger protein 813 2.18234
FSIP1 fibrous sheath interacting protein 1 2.17415
CCDC150 coiled-coil domain containing 150 2.15288
ANKLE1 ankyrin repeat and LEM domain containing 1 2.12232
TRIM27 tripartite motif containing 27 2.12171
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 2.12111
ZDHHC8 zinc finger, DHHC-type containing 8 2.12034
DCAF7 DDB1 and CUL4 associated factor 7 2.11655
MZT1 mitotic spindle organizing protein 1 2.11572
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 2.1083
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.08906
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.08906
PGBD5 piggyBac transposable element derived 5 2.08237
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 2.08237
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.04843
NDEL1 nudE neurodevelopment protein 1-like 1 2.04809
FAM117A family with sequence similarity 117, member A 2.04017
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 2.03747
CNOT7 CCR4-NOT transcription complex, subunit 7 2.03747
NFYA nuclear transcription factor Y, alpha 2.03629
ADRM1 adhesion regulating molecule 1 2.02872
CNN1 calponin 1, basic, smooth muscle 2.01918
FXYD6 FXYD domain containing ion transport regulator 6 2.01619
EXOC5 exocyst complex component 5 2.00814
FOXI3 forkhead box I3 2.0063

decreased expression

Symbol Name Standardized Value
TTC28 tetratricopeptide repeat domain 28 -2.93812
KLHL8 kelch-like family member 8 -2.93812
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) -2.93812
SKAP1 src kinase associated phosphoprotein 1 -2.93812
RANBP17 RAN binding protein 17 -2.92324
FGD1 FYVE, RhoGEF and PH domain containing 1 -2.90997
QSER1 glutamine and serine rich 1 -2.90997
F10 coagulation factor X -2.90997
VWC2 von Willebrand factor C domain containing 2 -2.90997
LYG2 lysozyme G-like 2 -2.90997
DCDC1 doublecortin domain containing 1 -2.90997
CBX4 chromobox homolog 4 -2.90997
AXIN1 axin 1 -2.90997
ZNF688 zinc finger protein 688 -2.90997
NPTXR neuronal pentraxin receptor -2.90997
C1R complement component 1, r subcomponent -2.90997
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -2.90997
ACAD8 acyl-CoA dehydrogenase family, member 8 -2.86609
CLNK cytokine-dependent hematopoietic cell linker -2.86423
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.86423
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -2.86423
FADS6 fatty acid desaturase 6 -2.86423
ZNF215 zinc finger protein 215 -2.86423
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 -2.86423
IL17D interleukin 17D -2.86423
TNNI1 troponin I type 1 (skeletal, slow) -2.86423
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.86423
NOS3 nitric oxide synthase 3 (endothelial cell) -2.86423
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -2.86423
TNC tenascin C -2.86423
COL8A2 collagen, type VIII, alpha 2 -2.86423
LKAAEAR1 LKAAEAR motif containing 1 -2.86423
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.86423
TMEM86B transmembrane protein 86B -2.86423
ATOH8 atonal homolog 8 (Drosophila) -2.86423
KISS1R KISS1 receptor -2.86423
CORT cortistatin -2.86423
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -2.86423
CALR3 calreticulin 3 -2.86423
GLB1L2 galactosidase, beta 1-like 2 -2.86423
TSLIG3C tRNA splicing ligase complex subunit 3C -2.86423
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled -2.86423
ZNF221 zinc finger protein 221 -2.86423
SLC25A34 solute carrier family 25, member 34 -2.86423
KCTD13 potassium channel tetramerization domain containing 13 -2.86423
ADPRHL1 ADP-ribosylhydrolase like 1 -2.86423
ESPNL espin-like -2.86423
SPACA9 sperm acrosome associated 9 -2.86423
GBX2 gastrulation brain homeobox 2 -2.86423
C20ORF144 chromosome 20 open reading frame 144 -2.86423
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -2.86423
HRH3 histamine receptor H3 -2.86423
AKAP6 A kinase (PRKA) anchor protein 6 -2.86423
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 -2.86423
LOC124902694 uncharacterized LOC124902694 -2.86423
FAM178B family with sequence similarity 178, member B -2.86423
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.86423
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -2.86423
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 -2.86423
NOX1 NADPH oxidase 1 -2.86423
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -2.86423
PSKH2 protein serine kinase H2 -2.86423
ACTN4 actinin, alpha 4 -2.80329
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.79721
PTPRD protein tyrosine phosphatase, receptor type, D -2.7892
MTCL1 microtubule crosslinking factor 1 -2.76775
KIF13B kinesin family member 13B -2.74835
ACE angiotensin I converting enzyme -2.73557
SZT2 seizure threshold 2 homolog (mouse) -2.71897
WDR86 WD repeat domain 86 -2.71709
EXOC3L2 exocyst complex component 3-like 2 -2.69648
C5 complement component 5 -2.69589
TMEM237 transmembrane protein 237 -2.61686
HDDC2 HD domain containing 2 -2.59259
POLR1E polymerase (RNA) I polypeptide E, 53kDa -2.59195
CNTN5 contactin 5 -2.59195
AZU1 azurocidin 1 -2.54479
ATP7A ATPase, Cu++ transporting, alpha polypeptide -2.54479
GULP1 GULP, engulfment adaptor PTB domain containing 1 -2.52062
ZNF696 zinc finger protein 696 -2.51808
SH3D19 SH3 domain containing 19 -2.47242
CCDC85A coiled-coil domain containing 85A -2.45385
ZC2HC1C zinc finger, C2HC-type containing 1C -2.44277
SHB Src homology 2 domain containing adaptor protein B -2.43146
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.43146
ZGPAT zinc finger, CCCH-type with G patch domain -2.43006
CHN2 chimerin 2 -2.41928
MEF2C myocyte enhancer factor 2C -2.36527
SHLD2 shieldin complex subunit 2 -2.36184
MZT2A mitotic spindle organizing protein 2A -2.35832
BCDIN3D BCDIN3 domain containing -2.32974
GHRHR growth hormone releasing hormone receptor -2.32006
PXN paxillin -2.32006
MYO7A myosin VIIA -2.32006
PRKCSH protein kinase C substrate 80K-H -2.32006
KLF10 Kruppel-like factor 10 -2.32006
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -2.31169
RBPJ recombination signal binding protein for immunoglobulin kappa J region -2.28903
ANKAR ankyrin and armadillo repeat containing -2.28903
HSF1 heat shock transcription factor 1 -2.28409
ZBTB47 zinc finger and BTB domain containing 47 -2.28409
LMF2 lipase maturation factor 2 -2.22287
USH2A Usher syndrome 2A (autosomal recessive, mild) -2.20549
HJV hemojuvelin BMP co-receptor -2.19765
RIPK4 receptor-interacting serine-threonine kinase 4 -2.19765
CNTN3 contactin 3 (plasmacytoma associated) -2.19765
RAD21L1 RAD21-like 1 (S. pombe) -2.19765
MYCBPAP MYCBP associated protein -2.19112
C1QTNF7 C1q and tumor necrosis factor related protein 7 -2.15207
MEAK7 MTOR associated protein, eak-7 homolog -2.14967
WFDC10B WAP four-disulfide core domain 10B -2.13568
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) -2.1333
TMEM14B transmembrane protein 14B -2.12111
GEMIN5 gem (nuclear organelle) associated protein 5 -2.11645
NOCT nocturnin -2.09836
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -2.09109
ATF7IP2 activating transcription factor 7 interacting protein 2 -2.0748
BBOF1 basal body orientation factor 1 -2.06196
DPP8 dipeptidyl-peptidase 8 -2.05989
EMID1 EMI domain containing 1 -2.05989
TMEM266 transmembrane protein 266 -2.05732
EYA2 EYA transcriptional coactivator and phosphatase 2 -2.05732
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -2.05447
UBXN2A UBX domain protein 2A -2.04868
ANKRD37 ankyrin repeat domain 37 -2.04809
H3C12 H3 clustered histone 12 -2.04809
BCAS2 breast carcinoma amplified sequence 2 -2.04099
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.04099
PKD2 polycystic kidney disease 2 (autosomal dominant) -2.03747
RBM12 RNA binding motif protein 12 -2.01786
WASF2 WAS protein family, member 2 -2.01628
CRYGS crystallin, gamma S -2.01541
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -2.01541
LPIN3 lipin 3 -2.01541
BCL2L11 BCL2-like 11 (apoptosis facilitator) -2.01376
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -2.0076
STOM stomatin -2.0063
SLC25A40 solute carrier family 25, member 40 -2.0063
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.0063
RESF1 retroelement silencing factor 1 -2.00328