ADAMTS13 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ADAM metallopeptidase with thrombospondin type 1 motif, 13|This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 11093)
External Link http://www.ncbi.nlm.nih.gov/gene/11093
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Genes

5 interacting proteins for ADAMTS13 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
B3GALTL beta 1,3-galactosyltransferase-like
F8 coagulation factor VIII, procoagulant component
NRF1 nuclear respiratory factor 1
POFUT2 protein O-fucosyltransferase 2
VWF von Willebrand factor