ADCY6 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description adenylate cyclase 6|This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015] (NCBI Entrez Gene Database, 112)
External Link http://www.ncbi.nlm.nih.gov/gene/112
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38 interacting proteins for ADCY6 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AKAP5 A kinase (PRKA) anchor protein 5
ATXN1 ataxin 1
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
EDN1 endothelin 1
EDNRA endothelin receptor type A
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAS GNAS complex locus
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
IQGAP1 IQ motif containing GTPase activating protein 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCE protein kinase C, epsilon
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
UBC ubiquitin C