ADO Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description 2-aminoethanethiol (cysteamine) dioxygenase|Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 84890)
External Link https://ncbi.nlm.nih.gov/gene/84890
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Genes

498 genes differentially expressed following the ADO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0178134
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0144151
PLAAT3 phospholipase A and acyltransferase 3 0.013806
CLIC5 chloride intracellular channel 5 0.0133861
HSPA1A heat shock 70kDa protein 1A 0.0129939
IPO13 importin 13 0.0127147
SCGB1D2 secretoglobin, family 1D, member 2 0.0121645
NT5E 5'-nucleotidase, ecto (CD73) 0.0107878
COMP cartilage oligomeric matrix protein 0.0107838
SCGB2A1 secretoglobin, family 2A, member 1 0.0105225
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0104633
CCN2 cellular communication network factor 2 0.0104098
INHBA inhibin, beta A 0.0104008
MYO6 myosin VI 0.0103904
MYB v-myb avian myeloblastosis viral oncogene homolog 0.0102703
S100A11 S100 calcium binding protein A11 0.00966333
ESR1 estrogen receptor 1 0.00961502
PERP PERP, TP53 apoptosis effector 0.00956838
MALL mal, T-cell differentiation protein-like 0.00955073
TPSAB1 tryptase alpha/beta 1 0.00902297
SFRP4 secreted frizzled-related protein 4 0.00900871
LAMP5 lysosomal-associated membrane protein family, member 5 0.0088873
KRT14 keratin 14, type I 0.00880118
AEBP1 AE binding protein 1 0.00879093
DSP desmoplakin 0.00869198
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00861562
CTSV cathepsin V 0.00859757
NVL nuclear VCP-like 0.00856206
EPCAM epithelial cell adhesion molecule 0.008448
AMH anti-Mullerian hormone 0.00843116
TXN thioredoxin 0.00836783
CXCL8 chemokine (C-X-C motif) ligand 8 0.00836137
LGALS4 lectin, galactoside-binding, soluble, 4 0.00831844
RFTN1 raftlin, lipid raft linker 1 0.00825536
DOCK9 dedicator of cytokinesis 9 0.00817094
AMIGO2 adhesion molecule with Ig-like domain 2 0.00814598
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00812888
GAS6 growth arrest-specific 6 0.00811625
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00808878
ELANE elastase, neutrophil expressed 0.00800103
CLDN3 claudin 3 0.00784738
ARHGAP29 Rho GTPase activating protein 29 0.00779888
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00779078
FGFR1 fibroblast growth factor receptor 1 0.00776591
GOLGA8H golgin A8 family, member H 0.00774568
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00769202
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00761147
HOXC10 homeobox C10 0.00755351
CA12 carbonic anhydrase XII 0.00753283
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00752966
NINJ2 ninjurin 2 0.0074611
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00745875
GALC galactosylceramidase 0.00744891
SCGB2A2 secretoglobin, family 2A, member 2 0.00742478
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00738661
HOXC6 homeobox C6 0.00729421
AMDHD2 amidohydrolase domain containing 2 0.00723277
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00722255
TM4SF1 transmembrane 4 L six family member 1 0.00715415
AGR2 anterior gradient 2 0.00707276
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00706666
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00701689
KLK6 kallikrein-related peptidase 6 0.00700789
MFSD10 major facilitator superfamily domain containing 10 0.006981
CRIP1 cysteine-rich protein 1 (intestinal) 0.00695356
CTSD cathepsin D 0.00695186
BHLHE41 basic helix-loop-helix family, member e41 0.00694872
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00690256
SFN stratifin 0.00687482
ADGRF5 adhesion G protein-coupled receptor F5 0.00681935
PTK2B protein tyrosine kinase 2 beta 0.00680921
COL16A1 collagen, type XVI, alpha 1 0.00677632
TPPP3 tubulin polymerization-promoting protein family member 3 0.00676735
TFF1 trefoil factor 1 0.00675927
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0067156
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00665928
APOD apolipoprotein D 0.0066529
ZDHHC11 zinc finger, DHHC-type containing 11 0.00664954
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00663627
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00661507
TOB1 transducer of ERBB2, 1 0.00658465
KRT16 keratin 16, type I 0.00657276
IRX5 iroquois homeobox 5 0.00655863
CCNA2 cyclin A2 0.00652313
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00651298
COPG1 coatomer protein complex, subunit gamma 1 0.00648314
CTSZ cathepsin Z 0.00647303
SPAG1 sperm associated antigen 1 0.00643645
TFF3 trefoil factor 3 (intestinal) 0.00642864
PLPP2 phospholipid phosphatase 2 0.0064286
TACC2 transforming, acidic coiled-coil containing protein 2 0.00642234
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.00641991
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00639316
CYBA cytochrome b-245, alpha polypeptide 0.00636642
SLIRP SRA stem-loop interacting RNA binding protein 0.00636158
DPEP1 dipeptidase 1 (renal) 0.00636055
TXLNA taxilin alpha 0.00635785
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 0.00635046
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00634801
JUP junction plakoglobin 0.00631528
ACAT1 acetyl-CoA acetyltransferase 1 0.00626354
KIF5B kinesin family member 5B 0.0062597
E2F2 E2F transcription factor 2 0.00624201
CALML3 calmodulin-like 3 0.00622695
KLK5 kallikrein-related peptidase 5 0.00622172
CSTB cystatin B (stefin B) 0.00617407
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0061679
CRYAB crystallin, alpha B 0.00615162
ADIRF adipogenesis regulatory factor 0.00614785
HTRA1 HtrA serine peptidase 1 0.00613617
AZU1 azurocidin 1 0.0061296
GPX4 glutathione peroxidase 4 0.00611784
CAPN3 calpain 3, (p94) 0.00609262
LRRC15 leucine rich repeat containing 15 0.00607783
CLTB clathrin, light chain B 0.00607034
PRTN3 proteinase 3 0.00606724
ELN elastin 0.00603698
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00603362
GDF15 growth differentiation factor 15 0.00602504
LTBP2 latent transforming growth factor beta binding protein 2 0.00596041
AREG amphiregulin 0.00595246
KLF6 Kruppel-like factor 6 0.00594346
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00594137
RPS27L ribosomal protein S27-like 0.00593566
GAB2 GRB2-associated binding protein 2 0.00593401
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00592781
KLK10 kallikrein-related peptidase 10 0.00592695
AVL9 AVL9 homolog (S. cerevisiase) 0.00590377
HIP1R huntingtin interacting protein 1 related 0.00590241
KLK7 kallikrein-related peptidase 7 0.00589707
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00587214
ACTN4 actinin, alpha 4 0.0057946
PKP4 plakophilin 4 0.0057734
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00572654
ITM2C integral membrane protein 2C 0.00572462
RRAGC Ras-related GTP binding C 0.00568798
TACSTD2 tumor-associated calcium signal transducer 2 0.00568513
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00564196
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00563816
PKP2 plakophilin 2 0.00563433
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00560896
TMPRSS4 transmembrane protease, serine 4 0.00558318
DSG1 desmoglein 1 0.00557408
PODXL podocalyxin-like 0.00556955
CD81 CD81 molecule 0.0055509
ATP5MF ATP synthase membrane subunit f 0.00553391
HMGN3 high mobility group nucleosomal binding domain 3 0.00552235
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00551884
MARCKSL1 MARCKS-like 1 0.00550192
COBL cordon-bleu WH2 repeat protein 0.00549695
COL10A1 collagen, type X, alpha 1 0.00549599
ACAA2 acetyl-CoA acyltransferase 2 0.00548098
NIT2 nitrilase family, member 2 0.00547623
KDM5D lysine (K)-specific demethylase 5D 0.00544953
PYCARD PYD and CARD domain containing 0.00544301
CLEC11A C-type lectin domain family 11, member A 0.00543007
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00542503
PBLD phenazine biosynthesis-like protein domain containing 0.00542202
CST6 cystatin E/M 0.00541993
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00541979
ACAN aggrecan 0.0054066
AKAP9 A kinase (PRKA) anchor protein 9 0.00540416
SNF8 SNF8, ESCRT-II complex subunit 0.00539562
LAMP1 lysosomal-associated membrane protein 1 0.00539545
TNK2 tyrosine kinase, non-receptor, 2 0.00539104
PHF10 PHD finger protein 10 0.00538418
PECR peroxisomal trans-2-enoyl-CoA reductase 0.00537466
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00537296
SRGN serglycin 0.00532334
CPM carboxypeptidase M 0.00532234
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00531041
ECM1 extracellular matrix protein 1 0.00530402
RCAN1 regulator of calcineurin 1 0.00529869
COX17 COX17 cytochrome c oxidase copper chaperone 0.00528267
CCND3 cyclin D3 0.00527386
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00526902
TRAPPC6A trafficking protein particle complex 6A 0.0052488
TSPAN8 tetraspanin 8 0.00524753
THBS1 thrombospondin 1 0.00524695
MSLN mesothelin 0.00523842
SQSTM1 sequestosome 1 0.0052368
FTH1 ferritin, heavy polypeptide 1 0.00521884
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00520979
EHF ets homologous factor 0.00520249
DYNLL1 dynein, light chain, LC8-type 1 0.00519338
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00518014
CTBP2 C-terminal binding protein 2 0.00515814
VAMP8 vesicle-associated membrane protein 8 0.00515616
PEBP1 phosphatidylethanolamine binding protein 1 0.00515166
FOLR1 folate receptor 1 (adult) 0.0051505
BGN biglycan 0.00514898
SMAD7 SMAD family member 7 0.00514319
RTN3 reticulon 3 0.00514311
GGCT gamma-glutamylcyclotransferase 0.00512918
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00511712
ATP5IF1 ATP synthase inhibitory factor subunit 1 0.00509575
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.0050801
TIMP3 TIMP metallopeptidase inhibitor 3 0.00507826
GATA6 GATA binding protein 6 0.00507099
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00506594
GARS1 glycyl-tRNA synthetase 1 0.0050568
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00502143
CENPU centromere protein U 0.00499609
KRT7 keratin 7, type II 0.00498758
CLEC3B C-type lectin domain family 3, member B 0.00497628
MSN moesin 0.00496056
PLXND1 plexin D1 0.00495452
TTC39A tetratricopeptide repeat domain 39A 0.00495029
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00495019
NAV3 neuron navigator 3 0.00491732
TM7SF3 transmembrane 7 superfamily member 3 0.0049153
DPEP3 dipeptidase 3 0.00490855
RCAN3 RCAN family member 3 0.00490057
MISP mitotic spindle positioning 0.00489877
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00489258
LIMCH1 LIM and calponin homology domains 1 0.00488673
TRIM28 tripartite motif containing 28 0.00486937
MSRB2 methionine sulfoxide reductase B2 0.00486475
HSPA2 heat shock 70kDa protein 2 0.00485474
TBCD tubulin folding cofactor D 0.00485296
PAEP progestagen-associated endometrial protein 0.00484846
NADSYN1 NAD synthetase 1 0.00484277
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00483909
AK1 adenylate kinase 1 0.00483603
HMGB3 high mobility group box 3 0.00483599
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00483274
CST1 cystatin SN 0.00483246
PDZK1 PDZ domain containing 1 0.0048277
KRT6B keratin 6B, type II 0.00481301
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00479857
DHCR24 24-dehydrocholesterol reductase 0.00477444
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00476639
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00476539
SMS spermine synthase 0.00475974
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 0.00474556
DSC1 desmocollin 1 0.00473393
CHP1 calcineurin-like EF-hand protein 1 0.0047108
GRK2 G protein-coupled receptor kinase 2 0.00469624
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00468503
HMOX1 heme oxygenase 1 0.00468234
BCAS1 breast carcinoma amplified sequence 1 0.00468012
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.00467578
TECR trans-2,3-enoyl-CoA reductase 0.00467415
ACSL5 acyl-CoA synthetase long-chain family member 5 0.0046661
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00466224
MYO1B myosin IB 0.00465335
TPD52L1 tumor protein D52-like 1 0.00464296
PLEC plectin 0.00463213
HIST1H2BK histone cluster 1, H2bk 0.0046192

decreased expression

Symbol Name Standardized Value
SEPP1 selenoprotein P, plasma, 1 -0.0168593
XIC X chromosome inactivation center -0.0142069
NIBAN1 niban apoptosis regulator 1 -0.0141627
CLU clusterin -0.0124493
RNF167 ring finger protein 167 -0.0114639
GPC3 glypican 3 -0.0112957
TNC tenascin C -0.0110829
PRDX2 peroxiredoxin 2 -0.0108467
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0105823
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.0102636
EIF5A eukaryotic translation initiation factor 5A -0.0102469
BEX1 brain expressed, X-linked 1 -0.0102263
LAMA4 laminin, alpha 4 -0.0100399
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.009965
SLC35G2 solute carrier family 35, member G2 -0.00994183
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00967604
IFI16 interferon, gamma-inducible protein 16 -0.00967248
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.009568
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00917051
FABP7 fatty acid binding protein 7, brain -0.00914435
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00910455
IFI44L interferon-induced protein 44-like -0.00908943
PLTP phospholipid transfer protein -0.00906828
CPVL carboxypeptidase, vitellogenic-like -0.00893496
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.0089125
SPARCL1 SPARC-like 1 (hevin) -0.00886024
PEG3 paternally expressed 3 -0.00883183
DLK1 delta-like 1 homolog (Drosophila) -0.00874511
COL4A5 collagen, type IV, alpha 5 -0.00868242
CNR1 cannabinoid receptor 1 (brain) -0.00854359
DPYD dihydropyrimidine dehydrogenase -0.00853443
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00849007
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00848829
NTS neurotensin -0.00847608
CAV1 caveolin 1, caveolae protein, 22kDa -0.0084507
CADM1 cell adhesion molecule 1 -0.0084423
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00838207
CST3 cystatin C -0.00837616
F3 coagulation factor III (thromboplastin, tissue factor) -0.0083758
NID1 nidogen 1 -0.00831202
SDC2 syndecan 2 -0.00828305
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00814761
IFI44 interferon-induced protein 44 -0.00811579
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00806751
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00802612
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00795243
DMD dystrophin -0.00794988
NRN1 neuritin 1 -0.00794286
CHRDL1 chordin-like 1 -0.00792429
MYBPC1 myosin binding protein C, slow type -0.00787837
EPAS1 endothelial PAS domain protein 1 -0.00786975
CD36 CD36 molecule (thrombospondin receptor) -0.00776572
FHL1 four and a half LIM domains 1 -0.00772525
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00772055
GJA1 gap junction protein, alpha 1, 43kDa -0.00765634
FGL2 fibrinogen-like 2 -0.00762221
PRMT1 protein arginine methyltransferase 1 -0.00756048
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00754291
MMD monocyte to macrophage differentiation-associated -0.00753434
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00749161
LPAR6 lysophosphatidic acid receptor 6 -0.00742262
MEIS1 Meis homeobox 1 -0.00739167
TPBG trophoblast glycoprotein -0.00737529
SELL selectin L -0.00723107
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00720616
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00719086
BCL6 B-cell CLL/lymphoma 6 -0.00715633
STOM stomatin -0.00713491
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00712604
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00711558
RTN2 reticulon 2 -0.00706521
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00700931
CCNB1 cyclin B1 -0.00692482
NDFIP1 Nedd4 family interacting protein 1 -0.00688909
S100A9 S100 calcium binding protein A9 -0.00686266
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -0.00686234
GBP2 guanylate binding protein 2, interferon-inducible -0.00676982
AKR1C2 aldo-keto reductase family 1, member C2 -0.00676962
CD302 CD302 molecule -0.00674697
KRT13 keratin 13, type I -0.00672263
VWF von Willebrand factor -0.00671439
HILPDA hypoxia inducible lipid droplet-associated -0.00668617
CADPS2 Ca++-dependent secretion activator 2 -0.00668402
COL1A2 collagen, type I, alpha 2 -0.00666696
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -0.00664922
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00662765
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -0.00661047
DIO2 deiodinase, iodothyronine, type II -0.00660699
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0065676
ASPH aspartate beta-hydroxylase -0.00656494
TLE4 transducin-like enhancer of split 4 -0.00654033
RAD23B RAD23 homolog B (S. cerevisiae) -0.00653746
IL2RB interleukin 2 receptor, beta -0.00649331
SSBP2 single-stranded DNA binding protein 2 -0.00648727
MEIS2 Meis homeobox 2 -0.00645189
IGFBP5 insulin-like growth factor binding protein 5 -0.00644356
NCKAP1L NCK-associated protein 1-like -0.00643566
CHI3L2 chitinase 3-like 2 -0.00643516
APOB apolipoprotein B -0.00641992
PRF1 perforin 1 (pore forming protein) -0.00639848
H1-0 H1.0 linker histone -0.00639673
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.0063964
TUBB2A tubulin, beta 2A class IIa -0.00638191
LDB2 LIM domain binding 2 -0.00637103
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00635602
GPM6B glycoprotein M6B -0.00635203
SV2A synaptic vesicle glycoprotein 2A -0.00628188
HCP5 HLA complex P5 (non-protein coding) -0.00627217
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00626612
BCHE butyrylcholinesterase -0.00625341
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00624876
WLS wntless Wnt ligand secretion mediator -0.00624178
GRB7 growth factor receptor-bound protein 7 -0.00622446
GBP1 guanylate binding protein 1, interferon-inducible -0.00620285
NLGN4X neuroligin 4, X-linked -0.00617716
JAKMIP2 janus kinase and microtubule interacting protein 2 -0.00616992
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00616823
PDE4A phosphodiesterase 4A, cAMP-specific -0.00613567
PRKD3 protein kinase D3 -0.00613333
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -0.00613035
FGR FGR proto-oncogene, Src family tyrosine kinase -0.00612099
COL4A6 collagen, type IV, alpha 6 -0.00611176
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00610175
AK4 adenylate kinase 4 -0.00609313
ANGPT1 angiopoietin 1 -0.00609187
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00605751
FABP6 fatty acid binding protein 6, ileal -0.00603513
SYT11 synaptotagmin XI -0.00601551
HHEX hematopoietically expressed homeobox -0.00600857
A2M alpha-2-macroglobulin -0.00600745
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00599689
IDO1 indoleamine 2,3-dioxygenase 1 -0.00596493
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.0059622
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00595421
HOXB2 homeobox B2 -0.00595134
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00593033
CHGB chromogranin B -0.00592383
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00590741
ACP6 acid phosphatase 6, lysophosphatidic -0.00589405
ADA adenosine deaminase -0.00588268
MCTP1 multiple C2 domains, transmembrane 1 -0.00587736
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00586391
CD14 CD14 molecule -0.0058615
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00585909
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00585237
ZNF266 zinc finger protein 266 -0.00584289
IL1RN interleukin 1 receptor antagonist -0.0058359
IGSF3 immunoglobulin superfamily, member 3 -0.0058284
DPYSL3 dihydropyrimidinase-like 3 -0.00582594
CCNF cyclin F -0.00582328
TMSB15A thymosin beta 15a -0.00581799
CCK cholecystokinin -0.00581776
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.0058049
CD52 CD52 molecule -0.00579254
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00577785
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00577408
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.0057648
FERMT2 fermitin family member 2 -0.00574139
DLX2 distal-less homeobox 2 -0.00573138
TAL1 T-cell acute lymphocytic leukemia 1 -0.005722
CCDC47 coiled-coil domain containing 47 -0.0057068
SPTSSA serine palmitoyltransferase, small subunit A -0.00569012
ANXA6 annexin A6 -0.00565318
LRRC17 leucine rich repeat containing 17 -0.00564633
LAMP3 lysosomal-associated membrane protein 3 -0.00564511
CHKB choline kinase beta -0.0056328
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0056117
AQP1 aquaporin 1 (Colton blood group) -0.00560521
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.0055994
C7 complement component 7 -0.00559359
AFP alpha-fetoprotein -0.00559038
CAV2 caveolin 2 -0.00557184
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00556459
CD59 CD59 molecule, complement regulatory protein -0.0055558
ARG2 arginase 2 -0.00555537
MEN1 multiple endocrine neoplasia I -0.0055402
SERHL2 serine hydrolase-like 2 -0.00551059
CPD carboxypeptidase D -0.00550576
ACP2 acid phosphatase 2, lysosomal -0.00550318
CCR7 chemokine (C-C motif) receptor 7 -0.00549888
BMP4 bone morphogenetic protein 4 -0.00549836
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00548935
GAP43 growth associated protein 43 -0.00548061
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.0054744
SREBF1 sterol regulatory element binding transcription factor 1 -0.00546823
NES nestin -0.00546541
IRAK3 interleukin-1 receptor-associated kinase 3 -0.00546007
EDNRB endothelin receptor type B -0.00545896
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00545169
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00542417
ARHGAP6 Rho GTPase activating protein 6 -0.00542201
OLFM1 olfactomedin 1 -0.00539969
INSM1 insulinoma-associated 1 -0.00538984
FOXN3 forkhead box N3 -0.00538319
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00537903
HNMT histamine N-methyltransferase -0.00536691
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00536458
CD8A CD8a molecule -0.00535976
EIF3D eukaryotic translation initiation factor 3, subunit D -0.00535155
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00535007
CRELD2 cysteine-rich with EGF-like domains 2 -0.00534895
SEPTIN6 septin 6 -0.00533183
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00532964
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -0.0053254
MDH1 malate dehydrogenase 1, NAD (soluble) -0.005317
MRTFB myocardin related transcription factor B -0.00531305
VSNL1 visinin-like 1 -0.00530743
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00530335
F13A1 coagulation factor XIII, A1 polypeptide -0.00530072
DENND2B DENN domain containing 2B -0.00529171
NCAM1 neural cell adhesion molecule 1 -0.00527642
GANAB glucosidase, alpha; neutral AB -0.00526633
CD83 CD83 molecule -0.00526424
SALL2 spalt-like transcription factor 2 -0.00525226
IL13RA2 interleukin 13 receptor, alpha 2 -0.005249
PDE8B phosphodiesterase 8B -0.00523424
BAALC brain and acute leukemia, cytoplasmic -0.00523102
CD86 CD86 molecule -0.00521584
ERP44 endoplasmic reticulum protein 44 -0.00521519
CPE carboxypeptidase E -0.00520972
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00520937
CFI complement factor I -0.0052048
KIF5C kinesin family member 5C -0.00520277
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.00519834
AHSG alpha-2-HS-glycoprotein -0.00519747
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00519185
ALAS2 5'-aminolevulinate synthase 2 -0.00518852
DUOX2 dual oxidase 2 -0.00518771
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00518707
ARRB2 arrestin, beta 2 -0.00517288
SRSF1 serine/arginine-rich splicing factor 1 -0.00516137
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00514252
CLEC7A C-type lectin domain family 7, member A -0.00512548
ECHDC2 enoyl CoA hydratase domain containing 2 -0.00511654
IL33 interleukin 33 -0.00510858
AMPH amphiphysin -0.00510516
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00510504
PFN2 profilin 2 -0.00509351
FBXO11 F-box protein 11 -0.00509253
PADI3 peptidyl arginine deiminase, type III -0.00509025
PEA15 phosphoprotein enriched in astrocytes 15 -0.00507244
PBX1 pre-B-cell leukemia homeobox 1 -0.00507096
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00506908
LTF lactotransferrin -0.00506477
HIST3H2A histone cluster 3, H2a -0.00506086
MDFIC MyoD family inhibitor domain containing -0.00504559
MAGEA3 melanoma antigen family A3 -0.0050353
SOX11 SRY (sex determining region Y)-box 11 -0.00502801
NELL2 NEL-like 2 (chicken) -0.00501809