ADRB1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description adrenoceptor beta 1|The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 153)
External Link https://ncbi.nlm.nih.gov/gene/153
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Genes

499 genes differentially expressed following the ADRB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P 0.012308
LTF lactotransferrin 0.0103422
FBXO11 F-box protein 11 0.00996832
IRS2 insulin receptor substrate 2 0.00851656
RAD23B RAD23 homolog B (S. cerevisiae) 0.00831424
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00825003
DLK1 delta-like 1 homolog (Drosophila) 0.00779754
CCP110 centriolar coiled coil protein 110kDa 0.00778557
NUSAP1 nucleolar and spindle associated protein 1 0.00761691
GNAS GNAS complex locus 0.00743234
FAM120A family with sequence similarity 120A 0.0074223
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00737213
CNR1 cannabinoid receptor 1 (brain) 0.00718163
DHCR7 7-dehydrocholesterol reductase 0.00686005
PDIA3 protein disulfide isomerase family A, member 3 0.00675434
TFF1 trefoil factor 1 0.00665401
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00656043
TYRP1 tyrosinase-related protein 1 0.00655578
ZDHHC6 zinc finger, DHHC-type containing 6 0.00644214
GOLGA8A golgin A8 family, member A 0.00639471
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00632019
NRGN neurogranin (protein kinase C substrate, RC3) 0.00629632
NPR3 natriuretic peptide receptor 3 0.00616808
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00616119
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00612425
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00612242
FABP7 fatty acid binding protein 7, brain 0.00610724
SRSF5 serine/arginine-rich splicing factor 5 0.0061052
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00601277
CD1E CD1e molecule 0.00599489
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.0058956
GUCY2C guanylate cyclase 2C 0.00589503
TOB1 transducer of ERBB2, 1 0.00587894
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00587627
GLIPR1 GLI pathogenesis-related 1 0.0057615
CEP55 centrosomal protein 55kDa 0.00571362
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00570196
PAQR3 progestin and adipoQ receptor family member III 0.00570119
SFRP1 secreted frizzled-related protein 1 0.00567382
BEX1 brain expressed, X-linked 1 0.0056695
CPVL carboxypeptidase, vitellogenic-like 0.00566092
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00561703
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00561561
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.0055733
SOBP sine oculis binding protein homolog (Drosophila) 0.00554072
MRPS2 mitochondrial ribosomal protein S2 0.00550339
RFK riboflavin kinase 0.00548855
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00547762
PNISR PNN-interacting serine/arginine-rich protein 0.00546792
NEK2 NIMA-related kinase 2 0.00541761
SI sucrase-isomaltase (alpha-glucosidase) 0.00540322
REG3A regenerating islet-derived 3 alpha 0.00538877
MGAM maltase-glucoamylase 0.00538115
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00537026
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00533834
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00530851
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00529082
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00527759
CD1D CD1d molecule 0.00527181
FOXE1 forkhead box E1 0.00526202
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00525948
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00525771
TRIM37 tripartite motif containing 37 0.00525411
CKS2 CDC28 protein kinase regulatory subunit 2 0.00523597
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.00523339
MTARC1 mitochondrial amidoxime reducing component 1 0.00522622
NPC2 Niemann-Pick disease, type C2 0.00521647
CHKA choline kinase alpha 0.00520108
CDC20 cell division cycle 20 0.00518993
SCG5 secretogranin V 0.00518047
PMEL premelanosome protein 0.00517146
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00516107
COMMD8 COMM domain containing 8 0.00515406
HMGN5 high mobility group nucleosome binding domain 5 0.00514795
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00513091
FOXM1 forkhead box M1 0.00513013
SFN stratifin 0.00512381
PBX1 pre-B-cell leukemia homeobox 1 0.00511962
CST3 cystatin C 0.00511423
TPSAB1 tryptase alpha/beta 1 0.00510158
AGA aspartylglucosaminidase 0.00507566
MEP1A meprin A, alpha (PABA peptide hydrolase) 0.00507109
IFT74 intraflagellar transport 74 0.00505166
MAOA monoamine oxidase A 0.00505116
LGALS13 lectin, galactoside-binding, soluble, 13 0.00503191
PLP1 proteolipid protein 1 0.00502168
CXCL3 chemokine (C-X-C motif) ligand 3 0.00501843
FZD6 frizzled class receptor 6 0.00501419
ADAM9 ADAM metallopeptidase domain 9 0.00501335
OSTM1 osteopetrosis associated transmembrane protein 1 0.00498616
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00496683
TBL1X transducin (beta)-like 1X-linked 0.00496525
F13A1 coagulation factor XIII, A1 polypeptide 0.00493805
RXRA retinoid X receptor, alpha 0.00493793
MPO myeloperoxidase 0.00492603
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.00490721
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00490076
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00489773
TRAPPC3 trafficking protein particle complex 3 0.00488806
FCGBP Fc fragment of IgG binding protein 0.00486783
ING2 inhibitor of growth family, member 2 0.00486494
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00486404
EPHA4 EPH receptor A4 0.00486097
FAM46C family with sequence similarity 46, member C 0.00485784
HAUS3 HAUS augmin-like complex, subunit 3 0.00483509
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00483229
PEG3 paternally expressed 3 0.00481638
TLK2 tousled-like kinase 2 0.00480783
DCT dopachrome tautomerase 0.00480322
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00478374
E2F2 E2F transcription factor 2 0.00475909
RAB32 RAB32, member RAS oncogene family 0.00475754
TKTL1 transketolase-like 1 0.00472529
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00472228
BCHE butyrylcholinesterase 0.004708
ORC1 origin recognition complex, subunit 1 0.00470384
DBF4 DBF4 zinc finger 0.00468665
CENPU centromere protein U 0.00468503
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00467385
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00465529
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0046486
RSRP1 arginine/serine-rich protein 1 0.00464474
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00464023
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00463817
ERP29 endoplasmic reticulum protein 29 0.00463167
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0046199
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00458084
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00458012
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.00457017
SNAP25 synaptosomal-associated protein, 25kDa 0.0045578
ENO2 enolase 2 (gamma, neuronal) 0.00452794
STXBP2 syntaxin binding protein 2 0.00452302
RAD51C RAD51 paralog C 0.00450359
PARM1 prostate androgen-regulated mucin-like protein 1 0.00449511
FGL2 fibrinogen-like 2 0.00448844
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00448349
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0044803
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00447136
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00443091
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00441405
GCH1 GTP cyclohydrolase 1 0.00440025
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00439603
CALML5 calmodulin-like 5 0.0043873
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00438639
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00438264
MEN1 multiple endocrine neoplasia I 0.00438043
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00436774
CKAP4 cytoskeleton-associated protein 4 0.00435964
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00432253
OGFRL1 opioid growth factor receptor-like 1 0.00431833
SFPQ splicing factor proline/glutamine-rich 0.00429854
ADGRE1 adhesion G protein-coupled receptor E1 0.00429509
RNASEH2B ribonuclease H2, subunit B 0.0042934
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00429312
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.0042886
CCNG1 cyclin G1 0.00428327
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00428281
ERLIN2 ER lipid raft associated 2 0.00427602
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.00425996
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00425592
KIF20A kinesin family member 20A 0.00424786
CHGB chromogranin B 0.00423842
MELK maternal embryonic leucine zipper kinase 0.00423207
ACP6 acid phosphatase 6, lysophosphatidic 0.00422574
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00422495
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00422162
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.00421283
CORO2A coronin, actin binding protein, 2A 0.00420523
CDKN3 cyclin-dependent kinase inhibitor 3 0.00420299
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00419838
PSIP1 PC4 and SFRS1 interacting protein 1 0.00419678
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.00419308
CRYBG3 beta-gamma crystallin domain containing 3 0.00418425
AGR2 anterior gradient 2 0.00417637
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.00416938
EDN3 endothelin 3 0.00416746
MNS1 meiosis-specific nuclear structural 1 0.00416579
CGA glycoprotein hormones, alpha polypeptide 0.00416534
NFIB nuclear factor I/B 0.00416181
NANS N-acetylneuraminic acid synthase 0.00416174
FBXO5 F-box protein 5 0.0041614
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.00416033
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00415964
FLNA filamin A, alpha 0.00415634
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00414185
PITX3 paired-like homeodomain 3 0.00413159
IFT81 intraflagellar transport 81 0.0041286
FEN1 flap structure-specific endonuclease 1 0.00412158
CXCL5 chemokine (C-X-C motif) ligand 5 0.00410863
KLHL23 kelch-like family member 23 0.00409981
RGS10 regulator of G-protein signaling 10 0.00409748
SRRM1 serine/arginine repetitive matrix 1 0.00409493
PDHX pyruvate dehydrogenase complex, component X 0.00409084
PPT1 palmitoyl-protein thioesterase 1 0.00408348
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00408127
DDR2 discoidin domain receptor tyrosine kinase 2 0.00408028
PPA2 pyrophosphatase (inorganic) 2 0.00407164
CA9 carbonic anhydrase IX 0.0040715
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00406414
CAPZB capping protein (actin filament) muscle Z-line, beta 0.00406024
LMNB1 lamin B1 0.00405874
DHFR dihydrofolate reductase 0.0040525
TMX1 thioredoxin-related transmembrane protein 1 0.00404747
SAP30 Sin3A-associated protein, 30kDa 0.00403349
GTPBP8 GTP-binding protein 8 (putative) 0.00403273
PCP4 Purkinje cell protein 4 0.00403238
HMGB2 high mobility group box 2 0.00403127
CAPN3 calpain 3, (p94) 0.00402619
CD163 CD163 molecule 0.00401752
NANOG Nanog homeobox 0.00401578
CHMP3 charged multivesicular body protein 3 0.00401327
GREB1 growth regulation by estrogen in breast cancer 1 0.0040109
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.00400856
ROPN1B rhophilin associated tail protein 1B 0.004007
ADNP2 ADNP homeobox 2 0.00399648
MTIF2 mitochondrial translational initiation factor 2 0.00399403
FOXG1 forkhead box G1 0.00396994
CD44 CD44 molecule (Indian blood group) 0.00396159
CLASRP CLK4-associating serine/arginine rich protein 0.003956
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00394906
LRP4 low density lipoprotein receptor-related protein 4 0.00394538
CFP complement factor properdin 0.0039436
INSIG1 insulin induced gene 1 0.00394227
INSR insulin receptor 0.0039404
NBPF10 neuroblastoma breakpoint family, member 10 0.00393947
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00393228
PAX6 paired box 6 0.00392229
S100A2 S100 calcium binding protein A2 0.00391974
TIMELESS timeless circadian clock 0.00391393
OLFM4 olfactomedin 4 0.0039094
DLG5 discs, large homolog 5 (Drosophila) 0.00390712
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00390683
HK2 hexokinase 2 0.00390074
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00389024
ICMT isoprenylcysteine carboxyl methyltransferase 0.00388751
YEATS4 YEATS domain containing 4 0.00388709
KIF14 kinesin family member 14 0.00388544
YME1L1 YME1-like 1 ATPase 0.00388412
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.00388314
SEC63 SEC63 homolog (S. cerevisiae) 0.00388093
NTS neurotensin 0.00387394
RYR3 ryanodine receptor 3 0.00386547
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00386436
TYMS thymidylate synthetase 0.00385555
ENTR1 endosome associated trafficking regulator 1 0.0038542
DZIP1 DAZ interacting zinc finger protein 1 0.00384654
ARGLU1 arginine and glutamate rich 1 0.00384216
RMI1 RecQ mediated genome instability 1 0.00383946
HMGB1 high mobility group box 1 0.00383844

decreased expression

Symbol Name Standardized Value
ADIRF adipogenesis regulatory factor -0.0131553
XPO7 exportin 7 -0.01228
PCOLCE procollagen C-endopeptidase enhancer -0.0113445
DCN decorin -0.0112536
RGCC regulator of cell cycle -0.0110666
CA2 carbonic anhydrase II -0.010574
IFI27 interferon, alpha-inducible protein 27 -0.0105478
AQP1 aquaporin 1 (Colton blood group) -0.0104804
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00987994
G0S2 G0/G1 switch 2 -0.00976775
DEFB1 defensin, beta 1 -0.00971053
CCN2 cellular communication network factor 2 -0.00945569
ATF3 activating transcription factor 3 -0.00915556
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00913224
ECM1 extracellular matrix protein 1 -0.00893703
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00878666
STC2 stanniocalcin 2 -0.00853955
AREG amphiregulin -0.00830466
IRF7 interferon regulatory factor 7 -0.00819812
SPON1 spondin 1, extracellular matrix protein -0.00795783
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00785364
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00778443
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00776906
CFH complement factor H -0.00776636
AMOTL2 angiomotin like 2 -0.0077323
EGR2 early growth response 2 -0.00760692
ZBED2 zinc finger, BED-type containing 2 -0.00746427
SFRP4 secreted frizzled-related protein 4 -0.00744773
CRYAB crystallin, alpha B -0.00741106
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00740921
THBS2 thrombospondin 2 -0.00738719
DAXX death-domain associated protein -0.00731337
NT5E 5'-nucleotidase, ecto (CD73) -0.00730569
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00727385
EGFL6 EGF-like-domain, multiple 6 -0.00724181
FABP4 fatty acid binding protein 4, adipocyte -0.0072036
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00720202
KLK10 kallikrein-related peptidase 10 -0.00718438
GPR137B G protein-coupled receptor 137B -0.00708463
MX1 MX dynamin-like GTPase 1 -0.00703033
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00696826
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00691233
HSPB8 heat shock 22kDa protein 8 -0.00688515
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00687831
LIF leukemia inhibitory factor -0.0067845
LMCD1 LIM and cysteine-rich domains 1 -0.00678414
CCNG2 cyclin G2 -0.00672618
AEBP1 AE binding protein 1 -0.00671731
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00670841
SPON2 spondin 2, extracellular matrix protein -0.00670409
CLIC5 chloride intracellular channel 5 -0.006674
IL32 interleukin 32 -0.00665466
CSRP2 cysteine and glycine-rich protein 2 -0.00665288
TM4SF1 transmembrane 4 L six family member 1 -0.00665236
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00661801
C10ORF10 chromosome 10 open reading frame 10 -0.00657609
CAPG capping protein (actin filament), gelsolin-like -0.00656166
EGR3 early growth response 3 -0.00654934
CFI complement factor I -0.00651842
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00651214
MXRA5 matrix-remodelling associated 5 -0.00647227
PDGFRB platelet-derived growth factor receptor, beta polypeptide -0.00646396
RAI2 retinoic acid induced 2 -0.00646274
RAI14 retinoic acid induced 14 -0.00641687
CD200 CD200 molecule -0.00641491
SLAMF7 SLAM family member 7 -0.00640188
GEM GTP binding protein overexpressed in skeletal muscle -0.00636939
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00636364
RTN2 reticulon 2 -0.00636296
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00631616
CLEC3B C-type lectin domain family 3, member B -0.00629538
FRMD4B FERM domain containing 4B -0.00627429
JUP junction plakoglobin -0.00624701
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00622912
AHNAK2 AHNAK nucleoprotein 2 -0.00618653
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.00617563
TUBB2B tubulin, beta 2B class IIb -0.00616388
ARHGAP29 Rho GTPase activating protein 29 -0.0061546
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00609303
TNS1 tensin 1 -0.00609233
COL14A1 collagen, type XIV, alpha 1 -0.00608796
ELN elastin -0.00605596
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00605412
LAMP3 lysosomal-associated membrane protein 3 -0.00605175
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00604781
BCL2L1 BCL2-like 1 -0.00604061
SLC38A1 solute carrier family 38, member 1 -0.00601261
MGLL monoglyceride lipase -0.00598232
SASH1 SAM and SH3 domain containing 1 -0.00596629
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00591762
ALOX5 arachidonate 5-lipoxygenase -0.00590948
CLTB clathrin, light chain B -0.00590073
KLK6 kallikrein-related peptidase 6 -0.00590048
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00589514
FSCN1 fascin actin-bundling protein 1 -0.00588514
CBS cystathionine-beta-synthase -0.00587463
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.0058728
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.005839
EMP1 epithelial membrane protein 1 -0.00583244
IGFBP6 insulin-like growth factor binding protein 6 -0.00583083
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00582665
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00582507
MET MET proto-oncogene, receptor tyrosine kinase -0.00579927
COL3A1 collagen, type III, alpha 1 -0.00576711
TNNT1 troponin T type 1 (skeletal, slow) -0.00576575
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.00575529
LAMB3 laminin, beta 3 -0.00575104
TUBB2A tubulin, beta 2A class IIa -0.00574579
TSPAN3 tetraspanin 3 -0.00571968
BGN biglycan -0.00571476
EFHD1 EF-hand domain family, member D1 -0.0056869
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00568652
THBD thrombomodulin -0.00567086
PXDN peroxidasin -0.00565495
RCAN1 regulator of calcineurin 1 -0.00561577
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00558262
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00558195
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00557173
MME membrane metallo-endopeptidase -0.00556763
KIAA0040 KIAA0040 -0.00555805
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00554803
HBD hemoglobin, delta -0.00554657
MEF2C myocyte enhancer factor 2C -0.00554546
FMOD fibromodulin -0.00551865
GRB7 growth factor receptor-bound protein 7 -0.00551667
CFB complement factor B -0.00550523
GPER1 G protein-coupled estrogen receptor 1 -0.0055002
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.0054844
STK10 serine/threonine kinase 10 -0.00547988
EPHA2 EPH receptor A2 -0.00547967
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00547908
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00547757
LHFP lipoma HMGIC fusion partner -0.0054713
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00547016
NNMT nicotinamide N-methyltransferase -0.00541482
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00541467
INHBA inhibin, beta A -0.00539694
ASPN asporin -0.00539059
TES testin LIM domain protein -0.00538883
AHR aryl hydrocarbon receptor -0.00538546
TSPAN13 tetraspanin 13 -0.00535464
EPS8L1 EPS8-like 1 -0.00534921
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00534386
SCGB2A1 secretoglobin, family 2A, member 1 -0.00533378
GUSBP3 glucuronidase, beta pseudogene 3 -0.00533065
RFTN1 raftlin, lipid raft linker 1 -0.0053119
PTN pleiotrophin -0.00530439
ZFPM2 zinc finger protein, FOG family member 2 -0.0053039
COL5A1 collagen, type V, alpha 1 -0.00530257
HILPDA hypoxia inducible lipid droplet-associated -0.00529358
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00528786
APOD apolipoprotein D -0.00528401
TPST2 tyrosylprotein sulfotransferase 2 -0.00528398
CTSK cathepsin K -0.00528322
TPM2 tropomyosin 2 (beta) -0.00527697
BLNK B-cell linker -0.00526843
CRABP2 cellular retinoic acid binding protein 2 -0.0052631
GJA1 gap junction protein, alpha 1, 43kDa -0.00525743
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00524651
CCL4 chemokine (C-C motif) ligand 4 -0.00523117
ZMAT3 zinc finger, matrin-type 3 -0.00522312
ARMCX2 armadillo repeat containing, X-linked 2 -0.00522141
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00521865
FBLN2 fibulin 2 -0.00520202
EPS8L2 EPS8-like 2 -0.00520002
AKR1C2 aldo-keto reductase family 1, member C2 -0.00519497
CDK14 cyclin-dependent kinase 14 -0.00518063
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00517009
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00515955
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00515586
STX4 syntaxin 4 -0.00511886
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00510975
LUM lumican -0.00507782
ADAM10 ADAM metallopeptidase domain 10 -0.00507075
CEMIP cell migration inducing protein, hyaluronan binding -0.00506904
MN1 meningioma (disrupted in balanced translocation) 1 -0.00505492
COLEC12 collectin sub-family member 12 -0.00504117
IGF1 insulin-like growth factor 1 (somatomedin C) -0.0050362
KLK11 kallikrein-related peptidase 11 -0.00503276
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.00500642
OSBPL3 oxysterol binding protein-like 3 -0.00499695
LAT2 linker for activation of T cells family, member 2 -0.00499445
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00493976
FLNC filamin C, gamma -0.00493739
PTPRE protein tyrosine phosphatase, receptor type, E -0.0049252
ZCCHC24 zinc finger, CCHC domain containing 24 -0.0049219
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00491924
SYNGR3 synaptogyrin 3 -0.0049096
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00490472
MYH10 myosin, heavy chain 10, non-muscle -0.00490459
HMGA1 high mobility group AT-hook 1 -0.00488502
RNF167 ring finger protein 167 -0.00488488
SNCG synuclein, gamma (breast cancer-specific protein 1) -0.004877
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00487666
TGM2 transglutaminase 2 -0.00487479
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00483524
HTRA2 HtrA serine peptidase 2 -0.00483002
ZBTB16 zinc finger and BTB domain containing 16 -0.00482924
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00482784
SELL selectin L -0.00482291
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.0048227
RHOD ras homolog family member D -0.00482092
ICAM1 intercellular adhesion molecule 1 -0.0048176
CD248 CD248 molecule, endosialin -0.00481617
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00481258
DCHS1 dachsous cadherin-related 1 -0.00481173
NOS3 nitric oxide synthase 3 (endothelial cell) -0.00481104
C14ORF132 chromosome 14 open reading frame 132 -0.00479903
JPT1 Jupiter microtubule associated homolog 1 -0.00479699
ACP5 acid phosphatase 5, tartrate resistant -0.00477765
GPX3 glutathione peroxidase 3 -0.0047722
FGF13 fibroblast growth factor 13 -0.00477145
MYLK myosin light chain kinase -0.00476939
TSPAN7 tetraspanin 7 -0.00474993
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00474695
SLC43A3 solute carrier family 43, member 3 -0.00472903
ADGRE5 adhesion G protein-coupled receptor E5 -0.00472407
A2M alpha-2-macroglobulin -0.00471794
HSPA1A heat shock 70kDa protein 1A -0.00471597
HOPX HOP homeobox -0.00471276
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00471134
JCAD junctional cadherin 5 associated -0.0047101
TMEM47 transmembrane protein 47 -0.00470903
PLXNB2 plexin B2 -0.0047024
BLVRB biliverdin reductase B -0.0047012
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00469001
SNAI2 snail family zinc finger 2 -0.0046885
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00467499
MMP9 matrix metallopeptidase 9 -0.00466513
TGFB3 transforming growth factor, beta 3 -0.00466263
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00464339
FN1 fibronectin 1 -0.00463493
CP ceruloplasmin (ferroxidase) -0.00463174
KRT14 keratin 14, type I -0.00462449
CAVIN3 caveolae associated protein 3 -0.0046151
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00461009
HMBOX1 homeobox containing 1 -0.00460939
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00458627
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00458485
FBLN5 fibulin 5 -0.00457803
CAV2 caveolin 2 -0.00456494
IL15RA interleukin 15 receptor, alpha -0.00456162
LAMC2 laminin, gamma 2 -0.00456088
ALAS2 5'-aminolevulinate synthase 2 -0.00455796
IFITM2 interferon induced transmembrane protein 2 -0.00455744
SSBP2 single-stranded DNA binding protein 2 -0.00454103
MVP major vault protein -0.0045172
TGFBR3 transforming growth factor, beta receptor III -0.00451317
C9ORF3 chromosome 9 open reading frame 3 -0.004512
TMSB15A thymosin beta 15a -0.00451049