ADRBK1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description adrenergic, beta, receptor kinase 1|The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 156)
External Link http://www.ncbi.nlm.nih.gov/gene/156
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Genes

21 substrates of the kinase ADRBK1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ADIPOR1 adiponectin receptor 1
ADRB2 adrenoceptor beta 2, surface
CHRM2 cholinergic receptor, muscarinic 2
CLTB clathrin, light chain B
CXCR4 chemokine (C-X-C motif) receptor 4
EZR ezrin
HRH1 histamine receptor H1
IGF1R insulin-like growth factor 1 receptor
IRS1 insulin receptor substrate 1
KCNIP3 Kv channel interacting protein 3, calsenilin
MAPK14 mitogen-activated protein kinase 14
MSN moesin
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
RDX radixin
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD2 SMAD family member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TBXA2R thromboxane A2 receptor
TUBB3 tubulin, beta 3 class III