AES Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description amino-terminal enhancer of split|The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 166)
External Link http://www.ncbi.nlm.nih.gov/gene/166
Similar Terms
Downloads & Tools

Genes

43 interacting proteins for AES from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AR androgen receptor
ATN1 atrophin 1
ATXN1L ataxin 1-like
CAPN1 calpain 1, (mu/I) large subunit
CCL7 chemokine (C-C motif) ligand 7
DGCR6 DiGeorge syndrome critical region gene 6
ELAVL1 ELAV like RNA binding protein 1
GABARAP GABA(A) receptor-associated protein
GFI1B growth factor independent 1B transcription repressor
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HMGB1 high mobility group box 1
HNF1A HNF1 homeobox A
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
LEF1 lymphoid enhancer-binding factor 1
MAPK14 mitogen-activated protein kinase 14
MED31 mediator complex subunit 31
MSX1 msh homeobox 1
MVP major vault protein
NLK nemo-like kinase
POU2F1 POU class 2 homeobox 1
PRDM1 PR domain containing 1, with ZNF domain
PROP1 PROP paired-like homeobox 1
PTRH2 peptidyl-tRNA hydrolase 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPL18A ribosomal protein L18a
RUNX1 runt-related transcription factor 1
SH3GL3 SH3-domain GRB2-like 3
SIX1 SIX homeobox 1
SIX2 SIX homeobox 2
SIX3 SIX homeobox 3
SIX6 SIX homeobox 6
SMAD1 SMAD family member 1
SMAD4 SMAD family member 4
SNCAIP synuclein, alpha interacting protein
STYXL1 serine/threonine/tyrosine interacting-like 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE3 transducin-like enhancer of split 3
UBC ubiquitin C