| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the AG-013608-5909 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AGO4 | argonaute RISC catalytic component 4 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| BGN | biglycan |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALD1 | caldesmon 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD70 | CD70 molecule |
| COPE | coatomer protein complex, subunit epsilon |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DRICH1 | aspartate-rich 1 |
| EGR1 | early growth response 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| FAM134B | family with sequence similarity 134, member B |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| H2AFJ | H2A histone family, member J |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT140 | intraflagellar transport 140 |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL36G | interleukin 36, gamma |
| INHBA | inhibin, beta A |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL24 | kelch-like family member 24 |
| LOC729164 | hCG1732469 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPT | microtubule-associated protein tau |
| MEF2D | myocyte enhancer factor 2D |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MUC3A | mucin 3A, cell surface associated |
| MYF5 | myogenic factor 5 |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OGFR | opioid growth factor receptor |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PEX16 | peroxisomal biogenesis factor 16 |
| PLA1A | phospholipase A1 member A |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLCH1 | phospholipase C, eta 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODNL1 | podocan-like 1 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REG1A | regenerating islet-derived 1 alpha |
| RGS12 | regulator of G-protein signaling 12 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL7 | ribosomal protein L7 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMIM14 | small integral membrane protein 14 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STC2 | stanniocalcin 2 |
| TAPBPL | TAP binding protein-like |
| TJP3 | tight junction protein 3 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TNPO3 | transportin 3 |
| TNXB | tenascin XB |
| TPP1 | tripeptidyl peptidase I |
| TRAIP | TRAF interacting protein |
| TRIB3 | tribbles pseudokinase 3 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VASH1 | vasohibin 1 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF214 | zinc finger protein 214 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRS3 | bombesin-like receptor 3 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK18 | cyclin-dependent kinase 18 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRDL1 | chordin-like 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLDND1 | claudin domain containing 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CPNE7 | copine VII |
| CPOX | coproporphyrinogen oxidase |
| CTGF | connective tissue growth factor |
| DCLRE1A | DNA cross-link repair 1A |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DIO3 | deiodinase, iodothyronine, type III |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FKBP5 | FK506 binding protein 5 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR176 | G protein-coupled receptor 176 |
| GPR85 | G protein-coupled receptor 85 |
| GRAMD3 | GRAM domain containing 3 |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4E | histone cluster 1, H4e |
| HOXA6 | homeobox A6 |
| HOXD11 | homeobox D11 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IL6 | interleukin 6 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LMNB1 | lamin B1 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAK | male germ cell-associated kinase |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MIS12 | MIS12 kinetochore complex component |
| MOXD1 | monooxygenase, DBH-like 1 |
| MRAS | muscle RAS oncogene homolog |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NCALD | neurocalcin delta |
| NTF3 | neurotrophin 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OSBP2 | oxysterol binding protein 2 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDZK1 | PDZ domain containing 1 |
| PENK | proenkephalin |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB36 | RAB36, member RAS oncogene family |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCEL | sciellin |
| SCG2 | secretogranin II |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCRT1 | scratch family zinc finger 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMG2 | semenogelin II |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM230 | transmembrane protein 230 |
| TMEM74B | transmembrane protein 74B |
| TRIM25 | tripartite motif containing 25 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF516 | zinc finger protein 516 |
| ZNF770 | zinc finger protein 770 |