| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the AG-013608-5944 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALPK1 | alpha-kinase 1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| BAIAP3 | BAI1-associated protein 3 |
| BMP10 | bone morphogenetic protein 10 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CARD9 | caspase recruitment domain family, member 9 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DNM3 | dynamin 3 |
| EGFR | epidermal growth factor receptor |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPOR | erythropoietin receptor |
| ETNK2 | ethanolamine kinase 2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FAM155A | family with sequence similarity 155, member A |
| FAM46C | family with sequence similarity 46, member C |
| FCMR | Fc fragment of IgM receptor |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| GAS7 | growth arrest-specific 7 |
| GLP1R | glucagon-like peptide 1 receptor |
| GP5 | glycoprotein V (platelet) |
| GPR161 | G protein-coupled receptor 161 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IDS | iduronate 2-sulfatase |
| ING1 | inhibitor of growth family, member 1 |
| ITM2C | integral membrane protein 2C |
| KIAA0125 | KIAA0125 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LHX1 | LIM homeobox 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAPT | microtubule-associated protein tau |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MTSS1L | metastasis suppressor 1-like |
| MVB12B | multivesicular body subunit 12B |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| MYO1E | myosin IE |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NEK11 | NIMA-related kinase 11 |
| NFYA | nuclear transcription factor Y, alpha |
| NNAT | neuronatin |
| NPPB | natriuretic peptide B |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PHF20 | PHD finger protein 20 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB33A | RAB33A, member RAS oncogene family |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD1 | SMAD family member 1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SSTR5 | somatostatin receptor 5 |
| STAB2 | stabilin 2 |
| STK4 | serine/threonine kinase 4 |
| STX1A | syntaxin 1A (brain) |
| TAZ | tafazzin |
| TBX19 | T-box 19 |
| TH | tyrosine hydroxylase |
| TM2D1 | TM2 domain containing 1 |
| TMEM121 | transmembrane protein 121 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPMT | thiopurine S-methyltransferase |
| TRIM5 | tripartite motif containing 5 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VAMP5 | vesicle-associated membrane protein 5 |
| VPS9D1 | VPS9 domain containing 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF227 | zinc finger protein 227 |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ANKRD40 | ankyrin repeat domain 40 |
| ANKRD7 | ankyrin repeat domain 7 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATG10 | autophagy related 10 |
| AUTS2 | autism susceptibility candidate 2 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CCDC186 | coiled-coil domain containing 186 |
| CD1A | CD1a molecule |
| CDCP1 | CUB domain containing protein 1 |
| CDH18 | cadherin 18, type 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLGN | calmegin |
| CLSTN3 | calsyntenin 3 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM124B | family with sequence similarity 124B |
| FAM76A | family with sequence similarity 76, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FGF16 | fibroblast growth factor 16 |
| FOXN2 | forkhead box N2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCKR | glucokinase (hexokinase 4) regulator |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GIPC2 | GIPC PDZ domain containing family, member 2 |
| GPR27 | G protein-coupled receptor 27 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA4 | homeobox A4 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INHA | inhibin, alpha |
| IRF8 | interferon regulatory factor 8 |
| JAM3 | junctional adhesion molecule 3 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LOC257152 | uncharacterized LOC257152 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAL | mal, T-cell differentiation protein |
| MCC | mutated in colorectal cancers |
| MED31 | mediator complex subunit 31 |
| MYO15A | myosin XVA |
| NAG18 | NAG18 mRNA |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OLFML2B | olfactomedin-like 2B |
| PADI1 | peptidyl arginine deiminase, type I |
| PGBD5 | piggyBac transposable element derived 5 |
| PLCH2 | phospholipase C, eta 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| POU3F2 | POU class 3 homeobox 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PRDM16 | PR domain containing 16 |
| PRF1 | perforin 1 (pore forming protein) |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS53 | protease, serine, 53 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| QPCT | glutaminyl-peptide cyclotransferase |
| RASL11B | RAS-like, family 11, member B |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGB | Ras-related GTP binding B |
| SALL1 | spalt-like transcription factor 1 |
| SCG5 | secretogranin V |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SIX3 | SIX homeobox 3 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| STIM1 | stromal interaction molecule 1 |
| STRN | striatin, calmodulin binding protein |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TARP | TCR gamma alternate reading frame protein |
| TIGD6 | tigger transposable element derived 6 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TPSG1 | tryptase gamma 1 |
| TRIM25 | tripartite motif containing 25 |
| TRIM36 | tripartite motif containing 36 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBA3D | tubulin, alpha 3d |
| WDR62 | WD repeat domain 62 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZIC3 | Zic family member 3 |