AG1478 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

18 kinases inhibited by the AG1478 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
EGFR epidermal growth factor receptor 1.36211
DDR1 discoidin domain receptor tyrosine kinase 1 1.21703
SLK STE20-like kinase 1.20983
ERBB4 erb-b2 receptor tyrosine kinase 4 1.11167
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.08845
MKNK1 MAP kinase interacting serine/threonine kinase 1 1.05057
LCK LCK proto-oncogene, Src family tyrosine kinase 1.01127
IRAK1 interleukin-1 receptor-associated kinase 1 1.00208
HIPK4 homeodomain interacting protein kinase 4 0.980114
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.959553
CHEK2 checkpoint kinase 2 0.955601
HCK HCK proto-oncogene, Src family tyrosine kinase 0.9517
RET ret proto-oncogene 0.944052
BLK BLK proto-oncogene, Src family tyrosine kinase 0.940302
CIT citron rho-interacting serine/threonine kinase 0.929345
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.922275
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.852752
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.852752