AGE RAGE pathway Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP2324.html
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Genes

66 proteins participating in the AGE RAGE pathway pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALPL alkaline phosphatase, liver/bone/kidney
ATF2 activating transcription factor 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDC42 cell division cycle 42
CHUK conserved helix-loop-helix ubiquitous kinase
CYCS cytochrome c, somatic
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DIAPH1 diaphanous-related formin 1
EGFR epidermal growth factor receptor
EZR ezrin
FOXO1 forkhead box O1
FOXO4 forkhead box O4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INHBB inhibin, beta B
INS insulin
INSR insulin receptor
IRAK4 interleukin-1 receptor-associated kinase 4
IRS1 insulin receptor substrate 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
LGALS3 lectin, galactoside-binding, soluble, 3
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSN moesin
MSR1 macrophage scavenger receptor 1
MYD88 myeloid differentiation primary response 88
NCF1 neutrophil cytosolic factor 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SOD1 superoxide dismutase 1, soluble
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein