AGS Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

330 genes with high or low expression in AGS relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 2.84767
PAGE4 P antigen family, member 4 (prostate associated) 2.79852
SSR1 signal sequence receptor, alpha 2.73456
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.71806
GLTSCR1 glioma tumor suppressor candidate region gene 1 2.69738
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.69629
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.5616
CREBBP CREB binding protein 2.53693
MYL7 myosin, light chain 7, regulatory 2.53386
EDAR ectodysplasin A receptor 2.49305
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 2.48317
SGPL1 sphingosine-1-phosphate lyase 1 2.47179
MYH4 myosin, heavy chain 4, skeletal muscle 2.43316
OVOL2 ovo-like zinc finger 2 2.37822
ZNF45 zinc finger protein 45 2.34358
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.31769
GALC galactosylceramidase 2.30896
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.30548
MICALL1 MICAL-like 1 2.3024
FPR3 formyl peptide receptor 3 2.28317
PRRC2C proline-rich coiled-coil 2C 2.2821
CST4 cystatin S 2.2629
CTSE cathepsin E 2.25893
PPY2P pancreatic polypeptide 2, pseudogene 2.25316
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.25288
CST1 cystatin SN 2.25287
PVR poliovirus receptor 2.24644
DGCR2 DiGeorge syndrome critical region gene 2 2.23515
OMP olfactory marker protein 2.22641
ACTN1 actinin, alpha 1 2.22608
EWSR1 EWS RNA-binding protein 1 2.21249
TMEM2 transmembrane protein 2 2.2055
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.15098
KDM6A lysine (K)-specific demethylase 6A 2.15069
YY1 YY1 transcription factor 2.13859
GATA4 GATA binding protein 4 2.13183
ACTN4 actinin, alpha 4 2.12832
TMBIM6 transmembrane BAX inhibitor motif containing 6 2.11305
AGMAT agmatine ureohydrolase (agmatinase) 2.09664
PGC progastricsin (pepsinogen C) 2.08129
ZNF8 zinc finger protein 8 2.075
RPS27L ribosomal protein S27-like 2.06949
CHMP4A charged multivesicular body protein 4A 2.04823
GPR52 G protein-coupled receptor 52 2.03515
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 2.02732
WNT6 wingless-type MMTV integration site family, member 6 2.02679
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.02412
GPR1 G protein-coupled receptor 1 2.01801
ATXN1 ataxin 1 2.0131
STX17 syntaxin 17 1.99968
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.97426
TM9SF3 transmembrane 9 superfamily member 3 1.97375
GPATCH2 G patch domain containing 2 1.97204
KTN1 kinectin 1 (kinesin receptor) 1.97101
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.96914
ACOT9 acyl-CoA thioesterase 9 1.96437
STK24 serine/threonine kinase 24 1.938
CEP76 centrosomal protein 76kDa 1.93708
RAB5A RAB5A, member RAS oncogene family 1.92186
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.91239
NPPB natriuretic peptide B 1.91103
EPPK1 epiplakin 1 1.90705
FKRP fukutin related protein 1.90437
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.89559
CEP170B centrosomal protein 170B 1.88547
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.88445
TJP1 tight junction protein 1 1.88323
NOL7 nucleolar protein 7, 27kDa 1.88193
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.87496
USP6NL USP6 N-terminal like 1.87374
VTN vitronectin 1.86594
C4BPB complement component 4 binding protein, beta 1.86554
CLCN4 chloride channel, voltage-sensitive 4 1.85585
BAG5 BCL2-associated athanogene 5 1.84804
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 1.84466
KHNYN KH and NYN domain containing 1.83682
CST2 cystatin SA 1.81058
GMFB glia maturation factor, beta 1.80778
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.80365
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.80294
HES2 hes family bHLH transcription factor 2 1.80058
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.79632
ZNF79 zinc finger protein 79 1.7961
LSR lipolysis stimulated lipoprotein receptor 1.77747
ZNF629 zinc finger protein 629 1.77543
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.77529
FGF20 fibroblast growth factor 20 1.7716
YAP1 Yes-associated protein 1 1.77057
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.76525
CRISP1 cysteine-rich secretory protein 1 1.76303
JPH2 junctophilin 2 1.74613
WBP4 WW domain binding protein 4 1.74603
GPR161 G protein-coupled receptor 161 1.73937
SOCS2 suppressor of cytokine signaling 2 1.73139
FKBP3 FK506 binding protein 3, 25kDa 1.73081
RASIP1 Ras interacting protein 1 1.72531
ADAM9 ADAM metallopeptidase domain 9 1.7149
ZNF613 zinc finger protein 613 1.71005
KCTD15 potassium channel tetramerization domain containing 15 1.70138
PRSS3P2 protease, serine, 3 pseudogene 2 1.69345
MSMB microseminoprotein, beta- 1.68792
PKP4 plakophilin 4 1.6829
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 1.68264
SPHK2 sphingosine kinase 2 1.67982
SON SON DNA binding protein 1.67521
ZNF410 zinc finger protein 410 1.66467
HOXD12 homeobox D12 1.66071
LGMN legumain 1.65568
SMPX small muscle protein, X-linked 1.65457
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.65303
ZNF544 zinc finger protein 544 1.64726
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 1.64397
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 1.6385
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 1.62382
MTMR8 myotubularin related protein 8 1.61808
ZFX zinc finger protein, X-linked 1.61266
N4BP1 NEDD4 binding protein 1 1.59797
MUS81 MUS81 structure-specific endonuclease subunit 1.59442
TMEM185B transmembrane protein 185B 1.58355
PZP pregnancy-zone protein 1.5811
PNMA1 paraneoplastic Ma antigen 1 1.57633
GFER growth factor, augmenter of liver regeneration 1.5759
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.5743
SCT secretin 1.57259
CCAR2 cell cycle and apoptosis regulator 2 1.57224
NMBR neuromedin B receptor 1.57165
ATP11A ATPase, class VI, type 11A 1.56979
SLC39A14 solute carrier family 39 (zinc transporter), member 14 1.56941
PRSS2 protease, serine, 2 (trypsin 2) 1.56582
OLA1 Obg-like ATPase 1 1.56368
LRRC42 leucine rich repeat containing 42 1.56238
NSD1 nuclear receptor binding SET domain protein 1 1.55885
F5 coagulation factor V (proaccelerin, labile factor) 1.55062
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 1.55034
GMDS GDP-mannose 4,6-dehydratase 1.54946
NEMF nuclear export mediator factor 1.54711
MARS methionyl-tRNA synthetase 1.54671
MARK4 MAP/microtubule affinity-regulating kinase 4 1.54475
ZNF468 zinc finger protein 468 1.54385
FUT2 fucosyltransferase 2 (secretor status included) 1.54363
TNMD tenomodulin 1.53746
BCORL1 BCL6 corepressor-like 1 1.53638
NOMO2 NODAL modulator 2 1.5351
MAML1 mastermind-like 1 (Drosophila) 1.534
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.53179
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.53089
BAMBI BMP and activin membrane-bound inhibitor 1.52938
NUPL1 nucleoporin like 1 1.52749
VASP vasodilator-stimulated phosphoprotein 1.52602
INVS inversin 1.52459
RCAN3 RCAN family member 3 1.52211
TAGLN transgelin 1.51939
EFCAB2 EF-hand calcium binding domain 2 1.51927
GSTM4 glutathione S-transferase mu 4 1.51735
DOCK5 dedicator of cytokinesis 5 1.51261
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.50681
CTAGE5 CTAGE family, member 5 1.5014
ZNF112 zinc finger protein 112 1.5012
CST8 cystatin 8 (cystatin-related epididymal specific) 1.50082
RIF1 replication timing regulatory factor 1 1.49484
WAPAL wings apart-like homolog (Drosophila) 1.49426
AEN apoptosis enhancing nuclease 1.49342
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.49258
MTMR6 myotubularin related protein 6 1.49178
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 1.48293
SDK1 sidekick cell adhesion molecule 1 1.4781
ARF1P1 ADP-ribosylation factor 1 pseudogene 1 1.47808
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.47222
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.46685
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 1.4661
CDRT1 CMT1A duplicated region transcript 1 1.46235
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.45968
RGN regucalcin 1.45617
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 1.45555
EXD2 exonuclease 3'-5' domain containing 2 1.45512
TP53BP1 tumor protein p53 binding protein 1 1.45465
CNIH1 cornichon family AMPA receptor auxiliary protein 1 1.44314
EPN1 epsin 1 1.44034
RPN2 ribophorin II 1.43838
SFTPC surfactant protein C 1.4379
OR12D3 olfactory receptor, family 12, subfamily D, member 3 1.43653
WDR44 WD repeat domain 44 1.43597
TMEM131 transmembrane protein 131 1.43326
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 1.4332
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.43282
BCAM basal cell adhesion molecule (Lutheran blood group) 1.43213
ING2 inhibitor of growth family, member 2 1.42856
GDF2 growth differentiation factor 2 1.42517
RAP2B RAP2B, member of RAS oncogene family 1.42377
COPB1 coatomer protein complex, subunit beta 1 1.42094
XPC xeroderma pigmentosum, complementation group C 1.41777

low expression

Symbol Name Standardized Value
DKFZP564C152 DKFZP564C152 protein -3.52977
CUTC cutC copper transporter -3.52195
ERI3 ERI1 exoribonuclease family member 3 -3.44256
IDS iduronate 2-sulfatase -3.08745
DHPS deoxyhypusine synthase -3.0142
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -3.00037
AARSD1 alanyl-tRNA synthetase domain containing 1 -2.84316
DVL3 dishevelled segment polarity protein 3 -2.73307
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -2.60121
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.55828
FBXO41 F-box protein 41 -2.48643
MCC mutated in colorectal cancers -2.4671
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -2.40562
TRIB3 tribbles pseudokinase 3 -2.40263
MLYCD malonyl-CoA decarboxylase -2.39961
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.36168
TAPBPL TAP binding protein-like -2.33702
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.2331
VAMP4 vesicle-associated membrane protein 4 -2.202
LETMD1 LETM1 domain containing 1 -2.20173
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -2.1939
PFDN5 prefoldin subunit 5 -2.18932
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) -2.17957
HHIPL2 HHIP-like 2 -2.17419
DCAF13 DDB1 and CUL4 associated factor 13 -2.16125
NCBP2 nuclear cap binding protein subunit 2, 20kDa -2.13542
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.12973
MT1G metallothionein 1G -2.11713
TEX261 testis expressed 261 -2.09488
PCBP1 poly(rC) binding protein 1 -2.08624
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -2.07887
DCAKD dephospho-CoA kinase domain containing -2.04035
ZNF271P zinc finger protein 271, pseudogene -2.02406
FERMT2 fermitin family member 2 -2.00818
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.00439
STIP1 stress-induced phosphoprotein 1 -2.00301
CRHR1 corticotropin releasing hormone receptor 1 -1.97065
RPS28 ribosomal protein S28 -1.94363
LACTB2 lactamase, beta 2 -1.93246
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -1.92583
UBE2I ubiquitin-conjugating enzyme E2I -1.92231
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -1.91455
TERF2 telomeric repeat binding factor 2 -1.90155
MPDU1 mannose-P-dolichol utilization defect 1 -1.90106
DOK5 docking protein 5 -1.89818
RRAGD Ras-related GTP binding D -1.89605
DLG4 discs, large homolog 4 (Drosophila) -1.89372
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -1.8848
YIPF5 Yip1 domain family, member 5 -1.87861
RPL35A ribosomal protein L35a -1.86948
USP39 ubiquitin specific peptidase 39 -1.86945
TRIM66 tripartite motif containing 66 -1.85952
PTX3 pentraxin 3, long -1.84957
PFN2 profilin 2 -1.84317
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -1.84154
THOC6 THO complex 6 -1.80982
RAB15 RAB15, member RAS oncogene family -1.8046
ITM2C integral membrane protein 2C -1.80114
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 -1.80009
ADIPOR2 adiponectin receptor 2 -1.79852
RNF130 ring finger protein 130 -1.7929
NEU1 sialidase 1 (lysosomal sialidase) -1.78684
HLTF helicase-like transcription factor -1.78346
FKBPL FK506 binding protein like -1.77986
ETV7 ets variant 7 -1.77801
SGSH N-sulfoglucosamine sulfohydrolase -1.77536
HIST1H2BE histone cluster 1, H2be -1.75131
PMM1 phosphomannomutase 1 -1.7394
PEF1 penta-EF-hand domain containing 1 -1.73847
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -1.73749
ZNF419 zinc finger protein 419 -1.73587
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -1.73296
GLUD1 glutamate dehydrogenase 1 -1.72358
ANXA5 annexin A5 -1.71598
PPARA peroxisome proliferator-activated receptor alpha -1.71366
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 -1.71184
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -1.70956
REPS1 RALBP1 associated Eps domain containing 1 -1.70455
CUTA cutA divalent cation tolerance homolog (E. coli) -1.69551
TONSL tonsoku-like, DNA repair protein -1.67558
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.67298
EIF5A eukaryotic translation initiation factor 5A -1.66935
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -1.64896
FZD1 frizzled class receptor 1 -1.64015
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -1.64002
FADS1 fatty acid desaturase 1 -1.61866
WDR76 WD repeat domain 76 -1.61833
CYC1 cytochrome c-1 -1.61203
ACAA2 acetyl-CoA acyltransferase 2 -1.60361
CNGB3 cyclic nucleotide gated channel beta 3 -1.60252
IL6R interleukin 6 receptor -1.59882
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) -1.59689
TREX1 three prime repair exonuclease 1 -1.59643
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -1.59322
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.58701
MAGED1 melanoma antigen family D1 -1.58376
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -1.58215
GMCL1 germ cell-less, spermatogenesis associated 1 -1.58167
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.58076
ELOVL5 ELOVL fatty acid elongase 5 -1.58
CDK9 cyclin-dependent kinase 9 -1.56308
ARMC9 armadillo repeat containing 9 -1.55942
KLHDC3 kelch domain containing 3 -1.55318
LIMD1 LIM domains containing 1 -1.55263
COPZ1 coatomer protein complex, subunit zeta 1 -1.54097
RPA2 replication protein A2, 32kDa -1.54055
F2R coagulation factor II (thrombin) receptor -1.53917
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -1.53837
SCRN1 secernin 1 -1.53587
MEGF9 multiple EGF-like-domains 9 -1.53474
TTLL1 tubulin tyrosine ligase-like family member 1 -1.53138
LINC00339 long intergenic non-protein coding RNA 339 -1.52805
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -1.52468
ENO1 enolase 1, (alpha) -1.52264
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.51937
ZHX2 zinc fingers and homeoboxes 2 -1.51229
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -1.50923
PGD phosphogluconate dehydrogenase -1.50477
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -1.49919
SATB1 SATB homeobox 1 -1.49877
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.49621
DBN1 drebrin 1 -1.49475
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -1.49122
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -1.48371
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -1.48303
PGS1 phosphatidylglycerophosphate synthase 1 -1.48069
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -1.47927
C1QL1 complement component 1, q subcomponent-like 1 -1.47329
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -1.47235
MVD mevalonate (diphospho) decarboxylase -1.4667
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -1.46309
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -1.4571
RRAGB Ras-related GTP binding B -1.44934
MVK mevalonate kinase -1.44634
GLRB glycine receptor, beta -1.42713
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.42695
IL11RA interleukin 11 receptor, alpha -1.42292
KDM1A lysine (K)-specific demethylase 1A -1.4173
AASS aminoadipate-semialdehyde synthase -1.4169