AHR Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description aryl hydrocarbon receptor|This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 196)
External Link https://ncbi.nlm.nih.gov/gene/196
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Genes

498 genes differentially expressed following the AHR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAS GNAS complex locus 0.00828944
SIRT3 sirtuin 3 0.00823165
FOLR1 folate receptor 1 (adult) 0.00816485
GREB1 growth regulation by estrogen in breast cancer 1 0.00767642
TPD52L1 tumor protein D52-like 1 0.00764493
EMX2 empty spiracles homeobox 2 0.00755432
HSPB1 heat shock 27kDa protein 1 0.00747182
XPO7 exportin 7 0.00745408
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.0070452
DEFB1 defensin, beta 1 0.00703357
FKBP5 FK506 binding protein 5 0.00698364
WASHC4 WASH complex subunit 4 0.00696164
HK1 hexokinase 1 0.00686227
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.00683092
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00681298
H1-10 H1.10 linker histone 0.006791
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00674242
ANXA3 annexin A3 0.00671063
RXYLT1 ribitol xylosyltransferase 1 0.00667759
GTF3A general transcription factor IIIA 0.0066161
GLUL glutamate-ammonia ligase 0.0065875
FXYD2 FXYD domain containing ion transport regulator 2 0.00655003
IFT57 intraflagellar transport 57 0.0065061
MSMB microseminoprotein, beta- 0.00635501
MSLN mesothelin 0.00629871
PDGFC platelet derived growth factor C 0.00628945
PDZK1 PDZ domain containing 1 0.00625491
RGS10 regulator of G-protein signaling 10 0.00623731
CETN2 centrin, EF-hand protein, 2 0.00616348
CAPG capping protein (actin filament), gelsolin-like 0.00615323
SOCS2 suppressor of cytokine signaling 2 0.00611017
CAV2 caveolin 2 0.00610622
LBH limb bud and heart development 0.00608154
YME1L1 YME1-like 1 ATPase 0.00607491
FGG fibrinogen gamma chain 0.00602629
HBD hemoglobin, delta 0.00596859
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00596425
PCLO piccolo presynaptic cytomatrix protein 0.00595623
CA2 carbonic anhydrase II 0.00592938
TGM2 transglutaminase 2 0.00589964
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00586326
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 0.00582074
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00581745
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.00580357
CSTB cystatin B (stefin B) 0.00580014
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00578519
ZBED2 zinc finger, BED-type containing 2 0.00575835
BUD31 BUD31 homolog (S. cerevisiae) 0.00574199
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00572929
SELENOT selenoprotein T 0.00568554
CORO1C coronin, actin binding protein, 1C 0.00566207
TFRC transferrin receptor 0.00565726
LSM1 LSM1, U6 small nuclear RNA associated 0.00564012
GPX1 glutathione peroxidase 1 0.00561882
MRPL42 mitochondrial ribosomal protein L42 0.00559873
FGA fibrinogen alpha chain 0.00559551
DNM1L dynamin 1-like 0.00556795
FCRL2 Fc receptor-like 2 0.00546496
MLF1 myeloid leukemia factor 1 0.00545326
CDH16 cadherin 16, KSP-cadherin 0.00543693
SINHCAF SIN3-HDAC complex associated factor 0.00541434
ARG2 arginase 2 0.00536433
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0053149
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00527888
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0052777
H1-2 H1.2 linker histone, cluster member 0.00526825
GET1 guided entry of tail-anchored proteins factor 1 0.00526451
GDI2 GDP dissociation inhibitor 2 0.00524937
PRPF18 pre-mRNA processing factor 18 0.00524114
TMEM243 transmembrane protein 243, mitochondrial 0.00524044
GSTP1 glutathione S-transferase pi 1 0.0052281
GRB7 growth factor receptor-bound protein 7 0.00520349
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00519962
MSMO1 methylsterol monooxygenase 1 0.00518578
DAZAP2 DAZ associated protein 2 0.00516991
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00516491
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00512899
NUSAP1 nucleolar and spindle associated protein 1 0.00511291
WDR61 WD repeat domain 61 0.00506564
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.0050494
MET MET proto-oncogene, receptor tyrosine kinase 0.00503501
C11ORF58 chromosome 11 open reading frame 58 0.0050007
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.00497163
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.0049657
KRT7 keratin 7, type II 0.00495876
GARS1 glycyl-tRNA synthetase 1 0.00495254
FGB fibrinogen beta chain 0.00494865
ZNF430 zinc finger protein 430 0.00492754
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00490955
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00489521
COG7 component of oligomeric golgi complex 7 0.00488894
FZD6 frizzled class receptor 6 0.00485109
PPID peptidylprolyl isomerase D 0.00484056
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.00484022
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.00481202
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00480368
CHPT1 choline phosphotransferase 1 0.00480299
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00480153
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00479019
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00477355
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.00476551
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.00475164
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00473017
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00472134
HMGB2 high mobility group box 2 0.00471787
APLP2 amyloid beta (A4) precursor-like protein 2 0.00471706
RNF14 ring finger protein 14 0.00471137
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.00469349
PRSS8 protease, serine, 8 0.00467903
NFYB nuclear transcription factor Y, beta 0.00465548
CP ceruloplasmin (ferroxidase) 0.00465293
RAB4A RAB4A, member RAS oncogene family 0.00464848
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.00464648
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.00464315
HCK HCK proto-oncogene, Src family tyrosine kinase 0.00461485
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00461195
PRPF4 pre-mRNA processing factor 4 0.00461056
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00460491
CTSB cathepsin B 0.00459867
DNTT DNA nucleotidylexotransferase 0.00459094
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.00459
EAPP E2F-associated phosphoprotein 0.00458772
ANXA2 annexin A2 0.00458716
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00457763
TLK2 tousled-like kinase 2 0.00455591
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.00454572
UBE2H ubiquitin-conjugating enzyme E2H 0.0045292
ARL3 ADP-ribosylation factor-like 3 0.00452836
SLPI secretory leukocyte peptidase inhibitor 0.00452176
ABI1 abl-interactor 1 0.00452012
ODC1 ornithine decarboxylase 1 0.00450814
BID BH3 interacting domain death agonist 0.00450319
CNOT8 CCR4-NOT transcription complex, subunit 8 0.00449272
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00448256
RFC2 replication factor C (activator 1) 2, 40kDa 0.00447548
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00447068
WNK1 WNK lysine deficient protein kinase 1 0.00446845
MZT2A mitotic spindle organizing protein 2A 0.00445471
FGFR2 fibroblast growth factor receptor 2 0.00442929
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00442633
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00441691
RNFT2 ring finger protein, transmembrane 2 0.00440709
CD1B CD1b molecule 0.00440141
MNS1 meiosis-specific nuclear structural 1 0.00439618
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.00439561
VAMP5 vesicle-associated membrane protein 5 0.00438873
CAPN7 calpain 7 0.00437861
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00437682
MAGEB2 melanoma antigen family B2 0.00435886
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00435383
JADE3 jade family PHD finger 3 0.00434048
RRM2 ribonucleotide reductase M2 0.00433681
ATAD2 ATPase family, AAA domain containing 2 0.00433474
MPP1 membrane protein, palmitoylated 1, 55kDa 0.00433396
IQCG IQ motif containing G 0.0043325
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00431559
CHMP4A charged multivesicular body protein 4A 0.00430369
ALAS2 5'-aminolevulinate synthase 2 0.00429962
CDC123 cell division cycle 123 0.00429755
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00429672
PXMP2 peroxisomal membrane protein 2, 22kDa 0.00429057
OGA O-GlcNAcase 0.00427016
SUMO1 small ubiquitin-like modifier 1 0.00426952
PCBP2 poly(rC) binding protein 2 0.00426903
HDDC2 HD domain containing 2 0.00426589
UGP2 UDP-glucose pyrophosphorylase 2 0.00425545
CDK14 cyclin-dependent kinase 14 0.00424921
CLDND1 claudin domain containing 1 0.00424585
PARL presenilin associated, rhomboid-like 0.00424547
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00423622
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00423238
TMCO3 transmembrane and coiled-coil domains 3 0.00422415
SMS spermine synthase 0.00422365
OSBPL10 oxysterol binding protein-like 10 0.00420786
AMDHD2 amidohydrolase domain containing 2 0.00420498
SH3YL1 SH3 and SYLF domain containing 1 0.00419549
PCP4 Purkinje cell protein 4 0.00419174
EXOC5 exocyst complex component 5 0.00418861
IPO13 importin 13 0.00418444
HSPA1A heat shock 70kDa protein 1A 0.00418267
STMN1 stathmin 1 0.00417932
ESD esterase D 0.00416873
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.00416619
EPB42 erythrocyte membrane protein band 4.2 0.00414768
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 0.00412052
BPGM 2,3-bisphosphoglycerate mutase 0.00411783
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00411507
BIK BCL2-interacting killer (apoptosis-inducing) 0.004101
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00409981
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00409045
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00408841
MED6 mediator complex subunit 6 0.00408578
ATG5 autophagy related 5 0.00408465
PRKCB protein kinase C, beta 0.00408387
H1-0 H1.0 linker histone 0.00408358
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00407629
TWSG1 twisted gastrulation BMP signaling modulator 1 0.00407224
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00407139
TRAM1 translocation associated membrane protein 1 0.00406166
CFAP298 cilia and flagella associated protein 298 0.00406115
CAPN1 calpain 1, (mu/I) large subunit 0.00405935
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00405696
NCOA4 nuclear receptor coactivator 4 0.00405524
SMYD2 SET and MYND domain containing 2 0.00405478
LRRC23 leucine rich repeat containing 23 0.0040417
PTPRO protein tyrosine phosphatase, receptor type, O 0.00403542
CRYBG1 crystallin beta-gamma domain containing 1 0.00403027
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00402506
PRMT1 protein arginine methyltransferase 1 0.00401709
GRB14 growth factor receptor-bound protein 14 0.00401647
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.0040156
FUCA1 fucosidase, alpha-L- 1, tissue 0.00400333
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.00399549
SH3GL3 SH3-domain GRB2-like 3 0.00399302
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00398559
PLK2 polo-like kinase 2 0.00398191
DGKA diacylglycerol kinase, alpha 80kDa 0.00397798
EMC3 ER membrane protein complex subunit 3 0.00396949
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00396876
SCN3B sodium channel, voltage gated, type III beta subunit 0.00396155
RANBP9 RAN binding protein 9 0.00395517
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 0.00395147
NMU neuromedin U 0.00395015
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 0.00394947
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.00394519
RBMX RNA binding motif protein, X-linked 0.00394249
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 0.00393827
CD200 CD200 molecule 0.00393772
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00392342
CD9 CD9 molecule 0.00392235
MARCHF5 membrane associated ring-CH-type finger 5 0.00391923
FABP6 fatty acid binding protein 6, ileal 0.0039156
PLSCR1 phospholipid scramblase 1 0.00390614
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.0038978
HSPH1 heat shock 105kDa/110kDa protein 1 0.00388684
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.0038868
RCAN1 regulator of calcineurin 1 0.0038848
CCDC28A coiled-coil domain containing 28A 0.00388446
GPN3 GPN-loop GTPase 3 0.0038729
AHSP alpha hemoglobin stabilizing protein 0.00386763
TAOK3 TAO kinase 3 0.00386428
CD1E CD1e molecule 0.00385983
RPL36AL ribosomal protein L36a-like 0.00385661
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.00385447
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00384289
MCM10 minichromosome maintenance complex component 10 0.00383514
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00383423
GGPS1 geranylgeranyl diphosphate synthase 1 0.00383352
GLOD4 glyoxalase domain containing 4 0.00383057
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.00382942

decreased expression

Symbol Name Standardized Value
HOPX HOP homeobox -0.0155255
SSBP2 single-stranded DNA binding protein 2 -0.015075
CXCL14 chemokine (C-X-C motif) ligand 14 -0.01311
PMP22 peripheral myelin protein 22 -0.0115551
SFN stratifin -0.0110636
PLXNC1 plexin C1 -0.0110507
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.0108703
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0105349
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0101157
SFRP4 secreted frizzled-related protein 4 -0.00968176
TFF3 trefoil factor 3 (intestinal) -0.00959732
STXBP2 syntaxin binding protein 2 -0.00951624
ACKR3 atypical chemokine receptor 3 -0.0094749
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00921968
STK10 serine/threonine kinase 10 -0.00892638
PLS3 plastin 3 -0.00873154
MFAP2 microfibrillar-associated protein 2 -0.00864786
PTCH1 patched 1 -0.00864549
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.0085986
CPA3 carboxypeptidase A3 (mast cell) -0.00859229
DLK1 delta-like 1 homolog (Drosophila) -0.00852781
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.008498
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00845039
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00843905
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00835841
MAP7 microtubule-associated protein 7 -0.0082482
GAS1 growth arrest-specific 1 -0.00818873
PROM1 prominin 1 -0.00807761
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.00800487
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00792442
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00790839
COL14A1 collagen, type XIV, alpha 1 -0.00787731
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00781835
KRT23 keratin 23, type I -0.00781122
DCN decorin -0.00779205
TGFB3 transforming growth factor, beta 3 -0.00768205
CTSK cathepsin K -0.00760928
ECM1 extracellular matrix protein 1 -0.00759955
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00755288
A2M alpha-2-macroglobulin -0.00751788
SCG5 secretogranin V -0.00749194
GREM1 gremlin 1, DAN family BMP antagonist -0.0074855
NRCAM neuronal cell adhesion molecule -0.00746529
COL15A1 collagen, type XV, alpha 1 -0.00744693
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00739669
HEPH hephaestin -0.00738137
VWF von Willebrand factor -0.00736055
SYNM synemin, intermediate filament protein -0.00733693
FABP4 fatty acid binding protein 4, adipocyte -0.00732977
ITM2A integral membrane protein 2A -0.00731569
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00731372
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00727933
GPX2 glutathione peroxidase 2 -0.00727726
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00723244
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00721182
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00720357
CD69 CD69 molecule -0.00718817
CNTN1 contactin 1 -0.00713047
JCHAIN joining chain of multimeric IgA and IgM -0.00710863
GOLGA8H golgin A8 family, member H -0.00707585
TPSAB1 tryptase alpha/beta 1 -0.00701493
S100A7 S100 calcium binding protein A7 -0.00696549
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00692679
LAMA4 laminin, alpha 4 -0.00691809
TGFBR3 transforming growth factor, beta receptor III -0.00684591
MYH11 myosin, heavy chain 11, smooth muscle -0.00682649
GPM6B glycoprotein M6B -0.00680928
COL16A1 collagen, type XVI, alpha 1 -0.00674545
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.00671859
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00667739
COL4A5 collagen, type IV, alpha 5 -0.00664096
CYTIP cytohesin 1 interacting protein -0.00662514
HMG20B high mobility group 20B -0.00659817
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00657552
RHOBTB3 Rho-related BTB domain containing 3 -0.00657238
TBX3 T-box 3 -0.00654959
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00653986
S100B S100 calcium binding protein B -0.00652151
SPARCL1 SPARC-like 1 (hevin) -0.0065193
RGS5 regulator of G-protein signaling 5 -0.00651704
ZEB2 zinc finger E-box binding homeobox 2 -0.00651454
SORBS1 sorbin and SH3 domain containing 1 -0.00646682
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00643124
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00641986
MINK1 misshapen-like kinase 1 -0.00640623
CCL20 chemokine (C-C motif) ligand 20 -0.00638841
CCL19 chemokine (C-C motif) ligand 19 -0.00636841
CLEC2B C-type lectin domain family 2, member B -0.00634237
INSM1 insulinoma-associated 1 -0.00631245
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.0062968
C1R complement component 1, r subcomponent -0.00628293
PDGFD platelet derived growth factor D -0.00627507
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -0.00623741
HLA-DRA major histocompatibility complex, class II, DR alpha -0.00622756
RCAN2 regulator of calcineurin 2 -0.00621874
ADGRF5 adhesion G protein-coupled receptor F5 -0.0061907
BTBD3 BTB (POZ) domain containing 3 -0.00617926
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00617417
G0S2 G0/G1 switch 2 -0.00615189
TOX3 TOX high mobility group box family member 3 -0.00613429
COLEC12 collectin sub-family member 12 -0.00612102
PDLIM3 PDZ and LIM domain 3 -0.006109
DCHS1 dachsous cadherin-related 1 -0.00610304
SRPX sushi-repeat containing protein, X-linked -0.00609262
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00607852
QKI QKI, KH domain containing, RNA binding -0.00607803
CD300A CD300a molecule -0.00606381
ZNF423 zinc finger protein 423 -0.00606316
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00602642
ZEB1 zinc finger E-box binding homeobox 1 -0.00592508
PLN phospholamban -0.00588082
AEBP1 AE binding protein 1 -0.00587647
TXLNA taxilin alpha -0.00586537
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00584883
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00583464
WLS wntless Wnt ligand secretion mediator -0.00581618
ISL1 ISL LIM homeobox 1 -0.00581408
RGS1 regulator of G-protein signaling 1 -0.00579863
NID2 nidogen 2 (osteonidogen) -0.0057908
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00578364
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00578128
S100P S100 calcium binding protein P -0.00577691
ANK2 ankyrin 2, neuronal -0.00577682
GBP1 guanylate binding protein 1, interferon-inducible -0.00576839
WIPF1 WAS/WASL interacting protein family, member 1 -0.00574449
LHFP lipoma HMGIC fusion partner -0.00573459
KIAA0125 KIAA0125 -0.00573231
CD96 CD96 molecule -0.00572484
SAMD4A sterile alpha motif domain containing 4A -0.00571675
NEFH neurofilament, heavy polypeptide -0.00569565
ABLIM1 actin binding LIM protein 1 -0.00568014
FCGBP Fc fragment of IgG binding protein -0.00567994
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00564961
NIBAN1 niban apoptosis regulator 1 -0.005638
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00562943
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00562913
ASPN asporin -0.00561221
IQGAP2 IQ motif containing GTPase activating protein 2 -0.0055792
KANK2 KN motif and ankyrin repeat domains 2 -0.00556843
CD36 CD36 molecule (thrombospondin receptor) -0.00555905
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00555187
SCD5 stearoyl-CoA desaturase 5 -0.00555081
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00554375
CD48 CD48 molecule -0.00553892
ANGPTL2 angiopoietin-like 2 -0.00550277
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00548933
THBS4 thrombospondin 4 -0.00547024
SCGB2A2 secretoglobin, family 2A, member 2 -0.00546744
C3AR1 complement component 3a receptor 1 -0.00545867
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00544195
OGN osteoglycin -0.00543214
WFDC1 WAP four-disulfide core domain 1 -0.00543031
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00542558
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00540437
PLSCR4 phospholipid scramblase 4 -0.00540015
COMP cartilage oligomeric matrix protein -0.00539707
TUBA4A tubulin, alpha 4a -0.00538108
LAPTM4B lysosomal protein transmembrane 4 beta -0.00536276
NOTCH1 notch 1 -0.00536123
C8ORF4 chromosome 8 open reading frame 4 -0.00532291
PDGFRL platelet-derived growth factor receptor-like -0.00532008
ELN elastin -0.0053
MTCL1 microtubule crosslinking factor 1 -0.00529888
COL3A1 collagen, type III, alpha 1 -0.00529453
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00529372
ITPKB inositol-trisphosphate 3-kinase B -0.00529219
COL5A2 collagen, type V, alpha 2 -0.00528696
FOXF1 forkhead box F1 -0.00528276
HPGDS hematopoietic prostaglandin D synthase -0.0052793
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00524604
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00523323
SDC1 syndecan 1 -0.00522309
GCH1 GTP cyclohydrolase 1 -0.00521871
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00520465
FNDC3B fibronectin type III domain containing 3B -0.00520014
SHOX2 short stature homeobox 2 -0.0051977
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00518188
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00517817
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00517409
PRR5L proline rich 5 like -0.00517351
ADRA2A adrenoceptor alpha 2A -0.00517136
LIMCH1 LIM and calponin homology domains 1 -0.00514
HOXA5 homeobox A5 -0.00513547
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00512851
SPRY2 sprouty homolog 2 (Drosophila) -0.00512298
RHOB ras homolog family member B -0.00511856
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00511701
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00511314
IL1R1 interleukin 1 receptor, type I -0.00511041
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00509496
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00508257
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00507875
OPHN1 oligophrenin 1 -0.00507683
STAB1 stabilin 1 -0.00506425
EGR2 early growth response 2 -0.00505721
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00505431
MFAP4 microfibrillar-associated protein 4 -0.00504407
COL21A1 collagen, type XXI, alpha 1 -0.00503971
ASPA aspartoacylase -0.00503895
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00503808
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -0.00502867
FBLN1 fibulin 1 -0.00502735
GBP2 guanylate binding protein 2, interferon-inducible -0.00502452
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00502414
UPP1 uridine phosphorylase 1 -0.00500681
MATN2 matrilin 2 -0.00499141
PIP prolactin-induced protein -0.00498631
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00498554
FRZB frizzled-related protein -0.00498474
IFI6 interferon, alpha-inducible protein 6 -0.00498438
HCLS1 hematopoietic cell-specific Lyn substrate 1 -0.00497698
PRDX2 peroxiredoxin 2 -0.00497273
NRIP3 nuclear receptor interacting protein 3 -0.0049678
MLPH melanophilin -0.00496118
C1S complement component 1, s subcomponent -0.00495332
FSTL1 follistatin-like 1 -0.00494347
MANSC1 MANSC domain containing 1 -0.00493286
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.0048983
TSPAN13 tetraspanin 13 -0.00488394
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00487854
CGA glycoprotein hormones, alpha polypeptide -0.00487703
GATA2 GATA binding protein 2 -0.00486943
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.00485651
CD320 CD320 molecule -0.00483505
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00483024
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00482268
NDRG1 N-myc downstream regulated 1 -0.00482083
MEN1 multiple endocrine neoplasia I -0.00482054
CD302 CD302 molecule -0.00480546
TYROBP TYRO protein tyrosine kinase binding protein -0.00480325
RNF19B ring finger protein 19B -0.00479866
LYZ lysozyme -0.00479614
CCR1 chemokine (C-C motif) receptor 1 -0.00479307
PDGFRB platelet-derived growth factor receptor, beta polypeptide -0.00479056
GAA glucosidase, alpha; acid -0.00478351
LAMA2 laminin, alpha 2 -0.0047815
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.0047656
SPP1 secreted phosphoprotein 1 -0.00475926
MORC4 MORC family CW-type zinc finger 4 -0.00475917
JAM3 junctional adhesion molecule 3 -0.00475052
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00474482
BSG basigin (Ok blood group) -0.0047441
FASN fatty acid synthase -0.00473946
RGS3 regulator of G-protein signaling 3 -0.00472958
ZBTB20 zinc finger and BTB domain containing 20 -0.00472555
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00472299
GATA6 GATA binding protein 6 -0.00471778
LGMN legumain -0.00470144