AIM2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description absent in melanoma 2|AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9447)
External Link https://ncbi.nlm.nih.gov/gene/9447
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Genes

499 genes differentially expressed following the AIM2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.024114
CNPY3 canopy FGF signaling regulator 3 0.0153271
CTSZ cathepsin Z 0.0132816
NVL nuclear VCP-like 0.0129792
PMP22 peripheral myelin protein 22 0.0125708
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.0120158
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0116586
REEP1 receptor accessory protein 1 0.0113959
MBL2 mannose-binding lectin (protein C) 2, soluble 0.0112605
GPX3 glutathione peroxidase 3 0.0112336
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0108394
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0107832
PAX6 paired box 6 0.0105988
SMC1A structural maintenance of chromosomes 1A 0.0105264
SUB1 SUB1 homolog (S. cerevisiae) 0.0104708
ASPH aspartate beta-hydroxylase 0.0103102
PHACTR2 phosphatase and actin regulator 2 0.0102915
ST18 suppression of tumorigenicity 18, zinc finger 0.010278
RCAN2 regulator of calcineurin 2 0.00996585
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00993848
PDLIM3 PDZ and LIM domain 3 0.00991062
VLDLR very low density lipoprotein receptor 0.00981518
YBX3 Y box binding protein 3 0.00964109
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00959299
DES desmin 0.00957516
COL4A5 collagen, type IV, alpha 5 0.00947618
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00942395
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00941064
IPO5 importin 5 0.00925321
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00902362
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00888971
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00887061
FASN fatty acid synthase 0.00876355
AKR1C3 aldo-keto reductase family 1, member C3 0.0087589
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00873353
IGFBP1 insulin-like growth factor binding protein 1 0.00873017
ACTB actin, beta 0.0086464
IDO1 indoleamine 2,3-dioxygenase 1 0.00863579
SLIT2 slit homolog 2 (Drosophila) 0.00856542
C3 complement component 3 0.00854218
SPART spartin 0.00850131
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00841956
NBPF10 neuroblastoma breakpoint family, member 10 0.00836816
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00836325
MOCOS molybdenum cofactor sulfurase 0.00833416
GCH1 GTP cyclohydrolase 1 0.00827486
RHOBTB3 Rho-related BTB domain containing 3 0.00827295
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00826605
KLHDC3 kelch domain containing 3 0.00826209
APOA2 apolipoprotein A-II 0.0081745
SDC2 syndecan 2 0.00812237
PLIN1 perilipin 1 0.0080427
DLK1 delta-like 1 homolog (Drosophila) 0.00799347
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00789891
COL6A2 collagen, type VI, alpha 2 0.00789842
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00787639
CBX6 chromobox homolog 6 0.00787116
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00782278
ELOVL5 ELOVL fatty acid elongase 5 0.00780741
SVIL supervillin 0.00780258
BAG2 BCL2-associated athanogene 2 0.00776497
DYNLL1 dynein, light chain, LC8-type 1 0.00774831
AKR1C2 aldo-keto reductase family 1, member C2 0.0077447
CXCL9 chemokine (C-X-C motif) ligand 9 0.00774223
GAL galanin/GMAP prepropeptide 0.00769262
RTN2 reticulon 2 0.00768264
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.00765755
GPC3 glypican 3 0.00764109
FADS1 fatty acid desaturase 1 0.00763635
HOMER2 homer scaffolding protein 2 0.00756682
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.0075181
FRS2 fibroblast growth factor receptor substrate 2 0.00751334
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00746638
AKR1C1 aldo-keto reductase family 1, member C1 0.00745019
NAV3 neuron navigator 3 0.00741323
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00741168
COL4A6 collagen, type IV, alpha 6 0.00736834
LGALS13 lectin, galactoside-binding, soluble, 13 0.00734588
LIMCH1 LIM and calponin homology domains 1 0.00728006
ADAM28 ADAM metallopeptidase domain 28 0.00723519
AFP alpha-fetoprotein 0.007221
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.0071954
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00718601
PYGL phosphorylase, glycogen, liver 0.00716585
SNX7 sorting nexin 7 0.00715015
DHDDS dehydrodolichyl diphosphate synthase 0.00714672
OBSL1 obscurin-like 1 0.00713232
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 0.00710873
TARDBP TAR DNA binding protein 0.00709547
RBPMS RNA binding protein with multiple splicing 0.00708925
SHTN1 shootin 1 0.00708559
FGL2 fibrinogen-like 2 0.00708328
CLGN calmegin 0.00707116
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00704418
INSM1 insulinoma-associated 1 0.00704157
TLE2 transducin-like enhancer of split 2 0.0070271
PROCR protein C receptor, endothelial 0.00702359
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00700884
FBLN1 fibulin 1 0.00700431
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.0069771
FOXF2 forkhead box F2 0.00696535
TOX3 TOX high mobility group box family member 3 0.00695905
H2AFV H2A histone family, member V 0.0069511
STEAP3 STEAP family member 3, metalloreductase 0.00693206
L1CAM L1 cell adhesion molecule 0.00684897
TCERG1 transcription elongation regulator 1 0.00682253
MTA1 metastasis associated 1 0.00675741
EREG epiregulin 0.00672348
SEPTIN10 septin 10 0.00671825
CD164 CD164 molecule, sialomucin 0.00666329
STK26 serine/threonine protein kinase 26 0.00664331
SCGN secretagogin, EF-hand calcium binding protein 0.00663438
CGA glycoprotein hormones, alpha polypeptide 0.00659302
HSPB8 heat shock 22kDa protein 8 0.00659114
COL15A1 collagen, type XV, alpha 1 0.0065699
PBX3 pre-B-cell leukemia homeobox 3 0.00656182
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00653326
TULP4 tubby like protein 4 0.00653129
SMTN smoothelin 0.00652728
CALCA calcitonin-related polypeptide alpha 0.0065268
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0065257
LAMP2 lysosomal-associated membrane protein 2 0.00650731
HOXB2 homeobox B2 0.00649754
TGFBR3 transforming growth factor, beta receptor III 0.00648865
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00648329
PITX1 paired-like homeodomain 1 0.00647494
PGC progastricsin (pepsinogen C) 0.00647466
RAD21 RAD21 homolog (S. pombe) 0.00645417
ISL1 ISL LIM homeobox 1 0.00642545
ZBTB18 zinc finger and BTB domain containing 18 0.00640745
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00639693
CXCL11 chemokine (C-X-C motif) ligand 11 0.00637875
RAPSN receptor-associated protein of the synapse 0.00636194
ANGPT1 angiopoietin 1 0.00634954
SRSF7 serine/arginine-rich splicing factor 7 0.00633994
SYNM synemin, intermediate filament protein 0.00629938
APOA1 apolipoprotein A-I 0.0062394
LPAR1 lysophosphatidic acid receptor 1 0.00623437
PLPP2 phospholipid phosphatase 2 0.00621943
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00620298
ELN elastin 0.00620151
CHGA chromogranin A 0.00619709
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.0061857
APOB apolipoprotein B 0.00616185
CREB1 cAMP responsive element binding protein 1 0.00614692
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.00613853
ANKRD10 ankyrin repeat domain 10 0.00613741
CRLF1 cytokine receptor-like factor 1 0.00613296
BTBD3 BTB (POZ) domain containing 3 0.00611601
LRRC1 leucine rich repeat containing 1 0.00611366
FOXF1 forkhead box F1 0.00610628
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.00608676
AMIGO2 adhesion molecule with Ig-like domain 2 0.00606598
DUSP5 dual specificity phosphatase 5 0.0060652
SRSF10 serine/arginine-rich splicing factor 10 0.00605178
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00603446
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.0060338
H2AX H2A.X variant histone 0.00603031
SORBS1 sorbin and SH3 domain containing 1 0.00603028
FOXA2 forkhead box A2 0.00601117
FN1 fibronectin 1 0.0060046
SHOX2 short stature homeobox 2 0.00599324
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00593089
SQLE squalene epoxidase 0.00592302
PDZRN3 PDZ domain containing ring finger 3 0.00591764
ACTC1 actin, alpha, cardiac muscle 1 0.00591615
TP73-AS1 TP73 antisense RNA 1 0.00590208
CIDEC cell death-inducing DFFA-like effector c 0.00589289
LGALS2 lectin, galactoside-binding, soluble, 2 0.00588575
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.00588564
PERP PERP, TP53 apoptosis effector 0.00587729
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00586625
AXL AXL receptor tyrosine kinase 0.00585786
MEIS2 Meis homeobox 2 0.00585699
DDR2 discoidin domain receptor tyrosine kinase 2 0.00584227
NNT nicotinamide nucleotide transhydrogenase 0.00582815
AHSG alpha-2-HS-glycoprotein 0.00581208
HOXA5 homeobox A5 0.00580978
MAPK6 mitogen-activated protein kinase 6 0.00580816
TNC tenascin C 0.00580392
PCLAF PCNA clamp associated factor 0.00579616
APLP1 amyloid beta (A4) precursor-like protein 1 0.00578162
ZBTB35 zinc finger and BTB domain containing 35 0.00577684
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.0057736
SELENOW selenoprotein W 0.00576951
CFH complement factor H 0.00576622
DCHS1 dachsous cadherin-related 1 0.00575997
CYB5R3 cytochrome b5 reductase 3 0.00575419
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.00574331
SRSF3 serine/arginine-rich splicing factor 3 0.00574282
CDC25B cell division cycle 25B 0.00574095
ZSCAN18 zinc finger and SCAN domain containing 18 0.00571461
TTN titin 0.00570151
PEG3 paternally expressed 3 0.0057008
LGALS8 lectin, galactoside-binding, soluble, 8 0.00569333
BCL2 B-cell CLL/lymphoma 2 0.00568656
CERK ceramide kinase 0.00568044
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00567877
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.00566114
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00565324
TMCO3 transmembrane and coiled-coil domains 3 0.00564913
PDE4DIP phosphodiesterase 4D interacting protein 0.00563464
GYG2 glycogenin 2 0.00559799
MFAP4 microfibrillar-associated protein 4 0.00559671
CASQ2 calsequestrin 2 (cardiac muscle) 0.00559011
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00558745
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00558081
CALML5 calmodulin-like 5 0.00557773
SFRP1 secreted frizzled-related protein 1 0.00557407
MCM2 minichromosome maintenance complex component 2 0.00557364
ARMC8 armadillo repeat containing 8 0.00556813
MEX3D mex-3 RNA binding family member D 0.00556571
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.00555868
FNDC3B fibronectin type III domain containing 3B 0.00555564
PTCD3 pentatricopeptide repeat domain 3 0.00555053
MB myoglobin 0.00553376
AGR2 anterior gradient 2 0.00552981
SPRY4 sprouty homolog 4 (Drosophila) 0.00550704
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00550223
LGMN legumain 0.00549363
RSRC2 arginine/serine-rich coiled-coil 2 0.0054929
DCLK1 doublecortin-like kinase 1 0.0054918
SREBF1 sterol regulatory element binding transcription factor 1 0.00547352
G0S2 G0/G1 switch 2 0.0054709
CHKB choline kinase beta 0.00545642
CPB1 carboxypeptidase B1 (tissue) 0.00545631
CCL8 chemokine (C-C motif) ligand 8 0.00544885
CD1E CD1e molecule 0.00543766
DMPK dystrophia myotonica-protein kinase 0.00542666
CCDC68 coiled-coil domain containing 68 0.00542525
DAPK1 death-associated protein kinase 1 0.00542026
F3 coagulation factor III (thromboplastin, tissue factor) 0.00541817
NAMPT nicotinamide phosphoribosyltransferase 0.00541454
NPTN neuroplastin 0.00540915
MEN1 multiple endocrine neoplasia I 0.0054063
KLHL23 kelch-like family member 23 0.00539553
CALR calreticulin 0.00539428
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 0.00539328
LAPTM4B lysosomal protein transmembrane 4 beta 0.00539056
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00538398
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00538057
SSBP2 single-stranded DNA binding protein 2 0.0053665
TYMP thymidine phosphorylase 0.00536352
SST somatostatin 0.00535832
TBC1D16 TBC1 domain family, member 16 0.00534632
SUN1 Sad1 and UNC84 domain containing 1 0.00534015
REC8 REC8 meiotic recombination protein 0.00533685
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00533414
TPPP3 tubulin polymerization-promoting protein family member 3 0.00532933
SOX13 SRY (sex determining region Y)-box 13 0.00532851

decreased expression

Symbol Name Standardized Value
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.016624
MT1X metallothionein 1X -0.0161795
MT1H metallothionein 1H -0.0150437
MT1E metallothionein 1E -0.0147636
MT1G metallothionein 1G -0.0140421
IFI27 interferon, alpha-inducible protein 27 -0.0139838
MT1HL1 metallothionein 1H-like 1 -0.0133334
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0132744
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.012604
GSTP1 glutathione S-transferase pi 1 -0.0125861
JCHAIN joining chain of multimeric IgA and IgM -0.0125668
ALCAM activated leukocyte cell adhesion molecule -0.0125643
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0118301
CSRP2 cysteine and glycine-rich protein 2 -0.0117083
TACSTD2 tumor-associated calcium signal transducer 2 -0.0115668
XIC X chromosome inactivation center -0.0115334
ADIRF adipogenesis regulatory factor -0.0114231
FXYD3 FXYD domain containing ion transport regulator 3 -0.0112979
MT2A metallothionein 2A -0.0111655
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0111554
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.0110674
CRYBG1 crystallin beta-gamma domain containing 1 -0.0109415
MT1F metallothionein 1F -0.0108563
THY1 Thy-1 cell surface antigen -0.0107582
ZMAT3 zinc finger, matrin-type 3 -0.0106991
CSTA cystatin A (stefin A) -0.0106512
KRT14 keratin 14, type I -0.0105196
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0103673
CRABP2 cellular retinoic acid binding protein 2 -0.0102224
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.0101503
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0100762
TP53I3 tumor protein p53 inducible protein 3 -0.00996649
RGS4 regulator of G-protein signaling 4 -0.00980824
AQP9 aquaporin 9 -0.0097195
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00962655
EGFL6 EGF-like-domain, multiple 6 -0.00962231
DAXX death-domain associated protein -0.00948386
MRPS16 mitochondrial ribosomal protein S16 -0.00943257
RPS27L ribosomal protein S27-like -0.00931947
HIST1H2BD histone cluster 1, H2bd -0.0092916
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00927298
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00926569
SCGB2A2 secretoglobin, family 2A, member 2 -0.00925935
ZNF185 zinc finger protein 185 (LIM domain) -0.0092591
TRIM29 tripartite motif containing 29 -0.00916269
HOPX HOP homeobox -0.00914217
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00910469
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00907538
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00898682
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.0089564
KRT5 keratin 5, type II -0.00894567
CLIC5 chloride intracellular channel 5 -0.0089034
COG7 component of oligomeric golgi complex 7 -0.00888134
C1ORF54 chromosome 1 open reading frame 54 -0.00883197
STK10 serine/threonine kinase 10 -0.00879797
ATOX1 antioxidant 1 copper chaperone -0.00876224
TP53TG1 TP53 target 1 (non-protein coding) -0.00869941
KLK10 kallikrein-related peptidase 10 -0.0086978
XYLT1 xylosyltransferase I -0.00865658
GRB7 growth factor receptor-bound protein 7 -0.00863555
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00863072
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0086199
ASS1 argininosuccinate synthase 1 -0.00858276
ALOX5 arachidonate 5-lipoxygenase -0.00848521
FOLR1 folate receptor 1 (adult) -0.00838766
LAMP3 lysosomal-associated membrane protein 3 -0.00835927
CEMIP cell migration inducing protein, hyaluronan binding -0.00834879
BAX BCL2-associated X protein -0.00833458
PI3 peptidase inhibitor 3, skin-derived -0.00827068
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00824262
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.0082201
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00820882
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00815452
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00811281
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00808854
SRGN serglycin -0.00805567
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00805288
BMP7 bone morphogenetic protein 7 -0.00803197
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00801542
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00800457
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00800439
SMAGP small cell adhesion glycoprotein -0.00797106
CA12 carbonic anhydrase XII -0.00796457
S100A11 S100 calcium binding protein A11 -0.00788076
CYRIA CYFIP related Rac1 interactor A -0.00785569
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00785413
TRIM22 tripartite motif containing 22 -0.00783111
GM2A GM2 ganglioside activator -0.00780612
DSG3 desmoglein 3 -0.00780361
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -0.00779594
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00776154
TARP TCR gamma alternate reading frame protein -0.00771096
AQP1 aquaporin 1 (Colton blood group) -0.00770842
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00768458
NEBL nebulette -0.00763842
DDB2 damage-specific DNA binding protein 2, 48kDa -0.00762449
CTSD cathepsin D -0.0076053
ECM1 extracellular matrix protein 1 -0.0076036
LDB2 LIM domain binding 2 -0.0075792
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00753737
IFITM1 interferon induced transmembrane protein 1 -0.00747687
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00745808
FKBP11 FK506 binding protein 11, 19 kDa -0.00744531
RPS26 ribosomal protein S26 -0.00744143
CAPG capping protein (actin filament), gelsolin-like -0.00743401
KRT15 keratin 15, type I -0.00741054
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00733534
NMRK1 nicotinamide riboside kinase 1 -0.00726001
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00723772
MMP12 matrix metallopeptidase 12 -0.00723625
LY96 lymphocyte antigen 96 -0.0072198
POU2AF1 POU class 2 associating factor 1 -0.00721431
GPR137B G protein-coupled receptor 137B -0.00721309
CRABP1 cellular retinoic acid binding protein 1 -0.00716061
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00712507
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.00708978
BAMBI BMP and activin membrane-bound inhibitor -0.00701991
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00700648
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00700076
DEFA4 defensin, alpha 4, corticostatin -0.00698133
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.0069576
MME membrane metallo-endopeptidase -0.00691605
DPEP1 dipeptidase 1 (renal) -0.00689171
TESC tescalcin -0.00684572
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00682637
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.00682507
LINC00623 long intergenic non-protein coding RNA 623 -0.00682243
ARG1 arginase 1 -0.00680173
GYPC glycophorin C (Gerbich blood group) -0.00678541
PDLIM2 PDZ and LIM domain 2 (mystique) -0.00677672
IGFBP6 insulin-like growth factor binding protein 6 -0.00677158
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00676247
CALB1 calbindin 1, 28kDa -0.00675508
MRPL40 mitochondrial ribosomal protein L40 -0.00673315
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00672942
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -0.00671743
IFI16 interferon, gamma-inducible protein 16 -0.00670018
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00668617
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00667691
S100P S100 calcium binding protein P -0.00667488
NT5E 5'-nucleotidase, ecto (CD73) -0.00667115
CLEC11A C-type lectin domain family 11, member A -0.00665279
MSLN mesothelin -0.00663403
IL1RN interleukin 1 receptor antagonist -0.00661571
CCN2 cellular communication network factor 2 -0.00659986
SOCS2 suppressor of cytokine signaling 2 -0.0065925
SYT1 synaptotagmin I -0.00656764
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00652902
NANS N-acetylneuraminic acid synthase -0.00652016
ZNHIT1 zinc finger, HIT-type containing 1 -0.00651594
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00651534
UBFD1 ubiquitin family domain containing 1 -0.00649324
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -0.00648966
MFAP3L microfibrillar-associated protein 3-like -0.00647975
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00647417
BCL2A1 BCL2-related protein A1 -0.00646761
SDC1 syndecan 1 -0.00643303
MXRA7 matrix-remodelling associated 7 -0.00642091
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.00640334
ZNF430 zinc finger protein 430 -0.00640199
SLPI secretory leukocyte peptidase inhibitor -0.0064001
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00639838
MSMO1 methylsterol monooxygenase 1 -0.00638191
IL2RG interleukin 2 receptor, gamma -0.00638048
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -0.00637298
BHMT betaine--homocysteine S-methyltransferase -0.00637264
RSL1D1 ribosomal L1 domain containing 1 -0.00637076
SH3YL1 SH3 and SYLF domain containing 1 -0.00636928
ELOB elongin B -0.00636206
COL11A1 collagen, type XI, alpha 1 -0.00630883
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.00629843
IGFBP4 insulin-like growth factor binding protein 4 -0.00629616
C5AR1 complement component 5a receptor 1 -0.00629434
TAOK1 TAO kinase 1 -0.00629153
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.00628377
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00627389
KDM5D lysine (K)-specific demethylase 5D -0.00626641
HTRA1 HtrA serine peptidase 1 -0.00626508
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00625953
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00622783
IFITM2 interferon induced transmembrane protein 2 -0.00622674
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00621624
UROS uroporphyrinogen III synthase -0.00620251
PON2 paraoxonase 2 -0.00620108
AREG amphiregulin -0.00619179
LY75 lymphocyte antigen 75 -0.00614345
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -0.00611677
GSTZ1 glutathione S-transferase zeta 1 -0.00610643
RNF187 ring finger protein 187 -0.00609113
CLDN8 claudin 8 -0.0060721
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00607182
DGKA diacylglycerol kinase, alpha 80kDa -0.00606836
BGN biglycan -0.00604604
RFTN1 raftlin, lipid raft linker 1 -0.00604401
MXI1 MAX interactor 1, dimerization protein -0.00603809
PCTP phosphatidylcholine transfer protein -0.00603653
ITK IL2-inducible T-cell kinase -0.00603581
SGK1 serum/glucocorticoid regulated kinase 1 -0.00603334
DPYS dihydropyrimidinase -0.00599328
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -0.0059806
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00596582
GSTK1 glutathione S-transferase kappa 1 -0.00595907
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.00595377
BIRC3 baculoviral IAP repeat containing 3 -0.00595377
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00594751
PTK2B protein tyrosine kinase 2 beta -0.00593803
ACOT7 acyl-CoA thioesterase 7 -0.00592432
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00591852
RHCG Rh family, C glycoprotein -0.00591455
ZBED2 zinc finger, BED-type containing 2 -0.00591099
FGFBP1 fibroblast growth factor binding protein 1 -0.00591072
NDE1 nudE neurodevelopment protein 1 -0.0059076
RUNX3 runt-related transcription factor 3 -0.00590414
ACP5 acid phosphatase 5, tartrate resistant -0.00590073
ARMCX2 armadillo repeat containing, X-linked 2 -0.00589869
SLAMF1 signaling lymphocytic activation molecule family member 1 -0.00589233
TMEM243 transmembrane protein 243, mitochondrial -0.00587232
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -0.00585781
ADD3 adducin 3 (gamma) -0.00585529
ATP10B ATPase, class V, type 10B -0.00585022
CCL5 chemokine (C-C motif) ligand 5 -0.00584683
BTK Bruton agammaglobulinemia tyrosine kinase -0.0058411
S100A12 S100 calcium binding protein A12 -0.0058221
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00582196
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00582141
ZNF652 zinc finger protein 652 -0.00581164
CLIP2 CAP-GLY domain containing linker protein 2 -0.00578823
GOLM1 golgi membrane protein 1 -0.00578664
PPID peptidylprolyl isomerase D -0.0057759
MEPCE methylphosphate capping enzyme -0.00577457
S100A14 S100 calcium binding protein A14 -0.00577313
ANXA1 annexin A1 -0.00576982
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00576825
GJA1 gap junction protein, alpha 1, 43kDa -0.00576625
ZNF395 zinc finger protein 395 -0.00576115
OASL 2'-5'-oligoadenylate synthetase-like -0.00576089
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00575821
FOXO1 forkhead box O1 -0.00575385
ETHE1 ethylmalonic encephalopathy 1 -0.00575134
CDK14 cyclin-dependent kinase 14 -0.00574299
FUCA1 fucosidase, alpha-L- 1, tissue -0.00572885
AMZ2 archaelysin family metallopeptidase 2 -0.00572415
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00571673
PTHLH parathyroid hormone-like hormone -0.005712
AOC1 amine oxidase, copper containing 1 -0.00570748
ANO1 anoctamin 1, calcium activated chloride channel -0.00569227
SERF2 small EDRK-rich factor 2 -0.00567912
DEFB1 defensin, beta 1 -0.00567198
CYTIP cytohesin 1 interacting protein -0.0056676