AIP Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description aryl hydrocarbon receptor interacting protein|The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] (NCBI Entrez Gene Database, 9049)
External Link https://ncbi.nlm.nih.gov/gene/9049
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Genes

499 genes differentially expressed following the AIP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SRPX sushi-repeat containing protein, X-linked 0.0152051
KIF2C kinesin family member 2C 0.0130582
APOD apolipoprotein D 0.0120456
TGFBI transforming growth factor, beta-induced, 68kDa 0.0118915
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0118698
TNC tenascin C 0.0108618
CDC20 cell division cycle 20 0.0104705
DES desmin 0.0104217
PMP22 peripheral myelin protein 22 0.0104148
PDGFC platelet derived growth factor C 0.0103499
C3 complement component 3 0.0101803
STK10 serine/threonine kinase 10 0.0101654
BCHE butyrylcholinesterase 0.0100669
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00992645
NOTCH2 notch 2 0.0099184
LGALS1 lectin, galactoside-binding, soluble, 1 0.00988228
TGM2 transglutaminase 2 0.00964674
MYH11 myosin, heavy chain 11, smooth muscle 0.009641
REG3A regenerating islet-derived 3 alpha 0.00948989
SFRP1 secreted frizzled-related protein 1 0.00940232
CST3 cystatin C 0.00934432
AGR2 anterior gradient 2 0.00933726
MGP matrix Gla protein 0.00930944
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00911187
SYNM synemin, intermediate filament protein 0.00896621
CD36 CD36 molecule (thrombospondin receptor) 0.00895599
PLN phospholamban 0.00882986
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00878456
CCL19 chemokine (C-C motif) ligand 19 0.00876168
GNAS GNAS complex locus 0.00873351
FRY furry homolog (Drosophila) 0.00870344
MELK maternal embryonic leucine zipper kinase 0.00870051
KANK1 KN motif and ankyrin repeat domains 1 0.00864233
SPEN spen family transcriptional repressor 0.00856126
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0085535
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00853088
SORBS1 sorbin and SH3 domain containing 1 0.00851763
NOTCH2NL notch 2 N-terminal like 0.00839746
SMTN smoothelin 0.00833267
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0083137
CLU clusterin 0.00826275
MAGEA3 melanoma antigen family A3 0.00819763
FABP4 fatty acid binding protein 4, adipocyte 0.00809582
SRGN serglycin 0.00805929
NID1 nidogen 1 0.0079423
COL15A1 collagen, type XV, alpha 1 0.00792434
NCAM1 neural cell adhesion molecule 1 0.00781636
ARID4B AT rich interactive domain 4B (RBP1-like) 0.00781425
NIBAN1 niban apoptosis regulator 1 0.00780889
EPS8 epidermal growth factor receptor pathway substrate 8 0.00778254
ZCCHC24 zinc finger, CCHC domain containing 24 0.00776556
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00774886
REG1B regenerating islet-derived 1 beta 0.00768622
AMIGO2 adhesion molecule with Ig-like domain 2 0.00766778
WWTR1 WW domain containing transcription regulator 1 0.00765063
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00762092
ZW10 zw10 kinetochore protein 0.00760993
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00751844
LIMS1 LIM and senescent cell antigen-like domains 1 0.0074578
CD302 CD302 molecule 0.00744251
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.00744036
HMG20B high mobility group 20B 0.00741816
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00739139
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00738852
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00734954
TSPAN7 tetraspanin 7 0.00722688
REG1A regenerating islet-derived 1 alpha 0.0072114
SPON2 spondin 2, extracellular matrix protein 0.00720689
SYNGR2 synaptogyrin 2 0.00720035
FILIP1L filamin A interacting protein 1-like 0.00717299
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00715093
AQP1 aquaporin 1 (Colton blood group) 0.00714009
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00713864
TGFBR3 transforming growth factor, beta receptor III 0.0071049
PLXNC1 plexin C1 0.00710301
ADARB1 adenosine deaminase, RNA-specific, B1 0.00710169
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00709789
SMC1A structural maintenance of chromosomes 1A 0.0070168
COL4A5 collagen, type IV, alpha 5 0.00697142
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.0069598
CNN1 calponin 1, basic, smooth muscle 0.00694457
CCDC47 coiled-coil domain containing 47 0.00694291
TSPAN13 tetraspanin 13 0.00692703
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.00691158
SVIL supervillin 0.00686777
PRC1 protein regulator of cytokinesis 1 0.00684923
CD93 CD93 molecule 0.00682482
CD320 CD320 molecule 0.00681558
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00678974
TIMP3 TIMP metallopeptidase inhibitor 3 0.00677559
SAMD4A sterile alpha motif domain containing 4A 0.00674254
TBC1D16 TBC1 domain family, member 16 0.00672754
QPCT glutaminyl-peptide cyclotransferase 0.0067104
LMOD1 leiomodin 1 (smooth muscle) 0.00669926
CPVL carboxypeptidase, vitellogenic-like 0.00668011
COL6A1 collagen, type VI, alpha 1 0.00666807
PDZRN3 PDZ domain containing ring finger 3 0.0066594
ANPEP alanyl (membrane) aminopeptidase 0.00665411
FASN fatty acid synthase 0.00665152
G6PD glucose-6-phosphate dehydrogenase 0.00660381
XIC X chromosome inactivation center 0.00658092
CERK ceramide kinase 0.00658062
SPARCL1 SPARC-like 1 (hevin) 0.0065803
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.00656387
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00652026
ADAMDEC1 ADAM-like, decysin 1 0.00652002
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00651132
SDC3 syndecan 3 0.00649396
MAGEA12 melanoma antigen family A12 0.00648929
APOLD1 apolipoprotein L domain containing 1 0.00648619
MOK MOK protein kinase 0.00642647
TIMP1 TIMP metallopeptidase inhibitor 1 0.00641825
RAPSN receptor-associated protein of the synapse 0.00640552
LAMA4 laminin, alpha 4 0.0063927
COMT catechol-O-methyltransferase 0.00639043
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00638652
C1ORF115 chromosome 1 open reading frame 115 0.00638233
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00637617
PLXNB2 plexin B2 0.00637512
PON2 paraoxonase 2 0.00637387
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00632002
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00630994
RUNX3 runt-related transcription factor 3 0.00628455
PRAME preferentially expressed antigen in melanoma 0.00626939
DMD dystrophin 0.00621278
DMBT1 deleted in malignant brain tumors 1 0.00619805
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00618564
SLC43A3 solute carrier family 43, member 3 0.0061535
GYPC glycophorin C (Gerbich blood group) 0.00614119
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00612148
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.00610566
KIAA0100 KIAA0100 0.00604867
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00603202
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00602866
CCL21 chemokine (C-C motif) ligand 21 0.00602508
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0060193
ZBTB35 zinc finger and BTB domain containing 35 0.0060073
OBSL1 obscurin-like 1 0.00599402
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00596205
LDOC1 leucine zipper, down-regulated in cancer 1 0.00596064
RAD23B RAD23 homolog B (S. cerevisiae) 0.00595653
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00595002
LPP LIM domain containing preferred translocation partner in lipoma 0.00594355
HMBOX1 homeobox containing 1 0.0059286
COL21A1 collagen, type XXI, alpha 1 0.00590941
CTSK cathepsin K 0.00589522
QKI QKI, KH domain containing, RNA binding 0.00589266
PDLIM3 PDZ and LIM domain 3 0.00588764
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00586632
MPDZ multiple PDZ domain protein 0.00585994
IL1R1 interleukin 1 receptor, type I 0.00585195
F13A1 coagulation factor XIII, A1 polypeptide 0.00584588
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 0.00583766
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 0.00583088
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00582158
COL6A2 collagen, type VI, alpha 2 0.0058122
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00581076
TYROBP TYRO protein tyrosine kinase binding protein 0.00580491
KYNU kynureninase 0.00579559
CFD complement factor D (adipsin) 0.00577455
TCTA T-cell leukemia translocation altered 0.00577163
ITGAV integrin, alpha V 0.00575127
PCNT pericentrin 0.00574783
XYLT1 xylosyltransferase I 0.00573284
TMX4 thioredoxin-related transmembrane protein 4 0.00572554
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00569877
GOLGA8H golgin A8 family, member H 0.00569121
PURA purine-rich element binding protein A 0.00567181
RNH1 ribonuclease/angiogenin inhibitor 1 0.00566271
KAT2B K(lysine) acetyltransferase 2B 0.00565246
GLB1L2 galactosidase, beta 1-like 2 0.005644
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00564347
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00560795
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00559675
TXNDC9 thioredoxin domain containing 9 0.00558333
SH2B3 SH2B adaptor protein 3 0.00555783
TMEM255A transmembrane protein 255A 0.00554319
AXIN1 axin 1 0.00554287
ADGRL4 adhesion G protein-coupled receptor L4 0.00551241
ASPH aspartate beta-hydroxylase 0.00549953
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00549879
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.00547286
MPRIP myosin phosphatase Rho interacting protein 0.00544575
ZMIZ1 zinc finger, MIZ-type containing 1 0.00543877
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00543716
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.00543695
PFN2 profilin 2 0.00541338
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00540959
TSPAN4 tetraspanin 4 0.00540488
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.0053881
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.0053665
GREM1 gremlin 1, DAN family BMP antagonist 0.00536042
CD99 CD99 molecule 0.00535555
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00534761
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0053224
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00530576
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00528081
TBL1X transducin (beta)-like 1X-linked 0.00526817
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00526621
PLXNA1 plexin A1 0.0052582
AADAC arylacetamide deacetylase 0.00524211
ERGIC2 ERGIC and golgi 2 0.00523452
FAM114A1 family with sequence similarity 114, member A1 0.00522031
PTTG1 pituitary tumor-transforming 1 0.00521158
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.00518475
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.0051842
FYCO1 FYVE and coiled-coil domain containing 1 0.00517758
EFHD2 EF-hand domain family, member D2 0.00517403
CD163 CD163 molecule 0.00516788
SPRY4 sprouty homolog 4 (Drosophila) 0.00515223
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0051463
SIDT2 SID1 transmembrane family, member 2 0.00514465
PLTP phospholipid transfer protein 0.00511819
CANT1 calcium activated nucleotidase 1 0.00511614
IGSF3 immunoglobulin superfamily, member 3 0.00510922
AVL9 AVL9 homolog (S. cerevisiase) 0.00510431
ZFAND6 zinc finger, AN1-type domain 6 0.00509681
TRIM9 tripartite motif containing 9 0.00509248
KANK2 KN motif and ankyrin repeat domains 2 0.00508885
PMEL premelanosome protein 0.00508634
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 0.00507281
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00506958
PDPK1 3-phosphoinositide dependent protein kinase 1 0.00506419
LAMA5 laminin, alpha 5 0.0050608
FLNC filamin C, gamma 0.00503832
LOC283683 uncharacterized LOC283683 0.00503173
CSF1R colony stimulating factor 1 receptor 0.00502176
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00500873
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00500021
TACC3 transforming, acidic coiled-coil containing protein 3 0.00499583
PDGFD platelet derived growth factor D 0.00498972
EHBP1L1 EH domain binding protein 1-like 1 0.00498717
DPYD dihydropyrimidine dehydrogenase 0.00498498
DROSHA drosha, ribonuclease type III 0.00498445
S100B S100 calcium binding protein B 0.00496967
COL6A3 collagen, type VI, alpha 3 0.00496818
ZEB1 zinc finger E-box binding homeobox 1 0.00496507
DST dystonin 0.00496252
TRPS1 trichorhinophalangeal syndrome I 0.00495594
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00494696
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00494594
NES nestin 0.00493274
TUBG1 tubulin, gamma 1 0.0049298
EMID1 EMI domain containing 1 0.00492689
ZFPM2 zinc finger protein, FOG family member 2 0.00492562
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00491781
PANK3 pantothenate kinase 3 0.00491375
DCHS1 dachsous cadherin-related 1 0.00490964
RTL8A retrotransposon Gag like 8A 0.00490492

decreased expression

Symbol Name Standardized Value
SIRT3 sirtuin 3 -0.0132997
CA2 carbonic anhydrase II -0.0128078
RGCC regulator of cell cycle -0.0121558
ADM adrenomedullin -0.0119396
CCN2 cellular communication network factor 2 -0.0114176
ANXA3 annexin A3 -0.0102665
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.0101184
KRT15 keratin 15, type I -0.00990362
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00968788
KLK10 kallikrein-related peptidase 10 -0.00940692
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00938159
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00935788
KLF6 Kruppel-like factor 6 -0.00932395
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00926723
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00897319
HIST1H2AC histone cluster 1, H2ac -0.00895535
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00895385
BMP2 bone morphogenetic protein 2 -0.0089367
SPIN1 spindlin 1 -0.00893178
EPS8L2 EPS8-like 2 -0.00858151
AQP3 aquaporin 3 (Gill blood group) -0.00855483
EPCAM epithelial cell adhesion molecule -0.00850848
SLPI secretory leukocyte peptidase inhibitor -0.00838308
ADD3 adducin 3 (gamma) -0.00833851
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00822971
PUF60 poly-U binding splicing factor 60KDa -0.00812267
CRABP2 cellular retinoic acid binding protein 2 -0.00806386
IL1RN interleukin 1 receptor antagonist -0.008057
PCYOX1 prenylcysteine oxidase 1 -0.00805597
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00796128
SCGB1D2 secretoglobin, family 1D, member 2 -0.00795585
SCGB2A1 secretoglobin, family 2A, member 1 -0.00794442
ASS1 argininosuccinate synthase 1 -0.00792991
SDC1 syndecan 1 -0.00792621
DIPK1A divergent protein kinase domain 1A -0.00787636
S100A12 S100 calcium binding protein A12 -0.00787474
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00787343
KRT14 keratin 14, type I -0.00766079
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.0076219
KLK11 kallikrein-related peptidase 11 -0.00761169
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00761089
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00759342
TSPAN8 tetraspanin 8 -0.0075909
ZBED2 zinc finger, BED-type containing 2 -0.00751175
IVNS1ABP influenza virus NS1A binding protein -0.00749696
TACSTD2 tumor-associated calcium signal transducer 2 -0.00749199
ATF3 activating transcription factor 3 -0.00748755
RNF141 ring finger protein 141 -0.0074417
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00743179
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00735954
FOLR1 folate receptor 1 (adult) -0.00733142
NIP7 NIP7, nucleolar pre-rRNA processing protein -0.00731046
KRT17 keratin 17, type I -0.00730477
NPR3 natriuretic peptide receptor 3 -0.00729848
SORBS2 sorbin and SH3 domain containing 2 -0.00728829
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00726492
CRABP1 cellular retinoic acid binding protein 1 -0.00717917
RIDA reactive intermediate imine deaminase A homolog -0.00716276
ZNF195 zinc finger protein 195 -0.00714098
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00707495
KRT13 keratin 13, type I -0.00707431
YIPF5 Yip1 domain family, member 5 -0.00707137
GLUL glutamate-ammonia ligase -0.00706197
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00702486
EXOC5 exocyst complex component 5 -0.00701574
CRCT1 cysteine-rich C-terminal 1 -0.00691489
NT5C2 5'-nucleotidase, cytosolic II -0.00686666
SAMD9 sterile alpha motif domain containing 9 -0.00686458
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00679083
CHEK1 checkpoint kinase 1 -0.00678059
PTHLH parathyroid hormone-like hormone -0.00675491
LTF lactotransferrin -0.00673315
TRIM22 tripartite motif containing 22 -0.00670158
NEFM neurofilament, medium polypeptide -0.00669707
GTPBP8 GTP-binding protein 8 (putative) -0.00665769
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00658056
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00657406
KRT16 keratin 16, type I -0.00656868
S100P S100 calcium binding protein P -0.00656668
HBEGF heparin-binding EGF-like growth factor -0.0065211
INHBA inhibin, beta A -0.00652033
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -0.00650899
ESRP1 epithelial splicing regulatory protein 1 -0.0064785
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00647379
IFI44L interferon-induced protein 44-like -0.0064515
RETREG1 reticulophagy regulator 1 -0.00644201
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00641878
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00639971
CDA cytidine deaminase -0.00638039
EDN1 endothelin 1 -0.00637713
IFITM1 interferon induced transmembrane protein 1 -0.00637238
VSNL1 visinin-like 1 -0.00635247
KLK6 kallikrein-related peptidase 6 -0.00634278
ISG15 ISG15 ubiquitin-like modifier -0.00633366
MRPL44 mitochondrial ribosomal protein L44 -0.00629689
CHP1 calcineurin-like EF-hand protein 1 -0.00627839
HIST1H2BD histone cluster 1, H2bd -0.0062724
KRT5 keratin 5, type II -0.00627106
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00626798
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00625102
MMP12 matrix metallopeptidase 12 -0.00625
BCCIP BRCA2 and CDKN1A interacting protein -0.00624701
MZB1 marginal zone B and B1 cell-specific protein -0.0062128
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00621232
SCEL sciellin -0.00618591
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00617625
RAB40B RAB40B, member RAS oncogene family -0.00616337
DEFB1 defensin, beta 1 -0.00616295
S100A2 S100 calcium binding protein A2 -0.00613059
CEMIP cell migration inducing protein, hyaluronan binding -0.00607066
CXADR coxsackie virus and adenovirus receptor -0.00605746
VNN1 vanin 1 -0.00602988
ABHD17B abhydrolase domain containing 17B -0.00602698
CLDND1 claudin domain containing 1 -0.00601987
DTX4 deltex 4, E3 ubiquitin ligase -0.00596986
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A -0.00594656
KRT6A keratin 6A, type II -0.00594642
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.00593857
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00591047
CDC37L1 cell division cycle 37-like 1 -0.0058926
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00589238
EREG epiregulin -0.00587343
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00584718
AGTPBP1 ATP/GTP binding protein 1 -0.00583708
MYOF myoferlin -0.00582499
PKP1 plakophilin 1 -0.00580249
CTSZ cathepsin Z -0.00578143
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00577579
IPO7 importin 7 -0.00577533
BPI bactericidal/permeability-increasing protein -0.00577188
STX3 syntaxin 3 -0.0057683
PGD phosphogluconate dehydrogenase -0.00575786
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00575722
LIAS lipoic acid synthetase -0.00575034
PAWR PRKC, apoptosis, WT1, regulator -0.00573128
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00573106
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.00571214
ANOS1 anosmin 1 -0.0057074
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00570577
C21ORF91 chromosome 21 open reading frame 91 -0.0057026
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -0.00569997
IFI44 interferon-induced protein 44 -0.00569591
PBX3 pre-B-cell leukemia homeobox 3 -0.0056942
WEE1 WEE1 G2 checkpoint kinase -0.0056881
NCBP2 nuclear cap binding protein subunit 2, 20kDa -0.00566574
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00566167
OPHN1 oligophrenin 1 -0.00564575
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -0.0056409
AKIRIN1 akirin 1 -0.00563596
AZU1 azurocidin 1 -0.00562859
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.0056118
HIST1H2BH histone cluster 1, H2bh -0.00559704
CES1 carboxylesterase 1 -0.00557983
EGR2 early growth response 2 -0.00557802
S100A8 S100 calcium binding protein A8 -0.00557106
KLF5 Kruppel-like factor 5 (intestinal) -0.00556468
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00556142
PRTN3 proteinase 3 -0.00555473
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0055475
CNN2 calponin 2 -0.00554146
SH3YL1 SH3 and SYLF domain containing 1 -0.00552251
AGTR1 angiotensin II receptor, type 1 -0.00552194
LY6H lymphocyte antigen 6 complex, locus H -0.00551938
MME membrane metallo-endopeptidase -0.00551443
SNAP25 synaptosomal-associated protein, 25kDa -0.00551288
DSP desmoplakin -0.00551254
NKX2-1 NK2 homeobox 1 -0.0054842
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00548289
DEFA4 defensin, alpha 4, corticostatin -0.00546925
CLDN10 claudin 10 -0.00546352
CAPRIN1 cell cycle associated protein 1 -0.00546313
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.00545737
S100A7 S100 calcium binding protein A7 -0.00545612
RPL14 ribosomal protein L14 -0.00542242
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.0054223
RAB14 RAB14, member RAS oncogene family -0.00542082
GCH1 GTP cyclohydrolase 1 -0.00541962
GPX1 glutathione peroxidase 1 -0.00541373
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00540648
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -0.0054059
LIG4 ligase IV, DNA, ATP-dependent -0.00540115
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00539767
CTSV cathepsin V -0.0053942
ISG20 interferon stimulated exonuclease gene 20kDa -0.00535368
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -0.00535184
ATXN3 ataxin 3 -0.00535138
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00533735
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00531021
TCTN2 tectonic family member 2 -0.00531019
PPID peptidylprolyl isomerase D -0.00530806
PI3 peptidase inhibitor 3, skin-derived -0.00530408
H1-2 H1.2 linker histone, cluster member -0.00530296
AREG amphiregulin -0.00530277
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00528949
P3H2 prolyl 3-hydroxylase 2 -0.00528614
CCK cholecystokinin -0.00528402
USP25 ubiquitin specific peptidase 25 -0.0052694
SCAMP1 secretory carrier membrane protein 1 -0.00526527
NMRK1 nicotinamide riboside kinase 1 -0.00526102
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00525876
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.0052587
FKBP14 FK506 binding protein 14, 22 kDa -0.00523925
TMOD3 tropomodulin 3 (ubiquitous) -0.00522095
CHMP1B charged multivesicular body protein 1B -0.00520333
CALB1 calbindin 1, 28kDa -0.00520037
PPA1 pyrophosphatase (inorganic) 1 -0.0051951
ZNF165 zinc finger protein 165 -0.00518455
C9ORF3 chromosome 9 open reading frame 3 -0.00518348
ABLIM1 actin binding LIM protein 1 -0.0051825
FGFR3 fibroblast growth factor receptor 3 -0.0051795
IL10RB interleukin 10 receptor, beta -0.00516421
COL8A1 collagen, type VIII, alpha 1 -0.00515715
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -0.00514281
MX1 MX dynamin-like GTPase 1 -0.00512964
SMIM8 small integral membrane protein 8 -0.00512358
ACOT13 acyl-CoA thioesterase 13 -0.00512205
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -0.00510728
CLC Charcot-Leyden crystal galectin -0.00510311
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00510009
CD52 CD52 molecule -0.00509974
FBP1 fructose-1,6-bisphosphatase 1 -0.00508778
TOX thymocyte selection-associated high mobility group box -0.00508632
GLG1 golgi glycoprotein 1 -0.00507159
EIF3H eukaryotic translation initiation factor 3, subunit H -0.00507122
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -0.0050631
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.0050606
PNMA2 paraneoplastic Ma antigen 2 -0.00505098
AK4 adenylate kinase 4 -0.0050508
MAL mal, T-cell differentiation protein -0.00503716
SPRR3 small proline-rich protein 3 -0.00503335
ALOX5 arachidonate 5-lipoxygenase -0.00503145
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00501236
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00500875
THY1 Thy-1 cell surface antigen -0.00499458
EHF ets homologous factor -0.00499428
AZIN1 antizyme inhibitor 1 -0.00499426
TALDO1 transaldolase 1 -0.00499332
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.00499309
DNTT DNA nucleotidylexotransferase -0.00497366
IER3IP1 immediate early response 3 interacting protein 1 -0.00497178
TUBB2A tubulin, beta 2A class IIa -0.00495741
NDRG1 N-myc downstream regulated 1 -0.00494844
CALCA calcitonin-related polypeptide alpha -0.00494224
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00493942
MCL1 myeloid cell leukemia 1 -0.00493937
TSPAN1 tetraspanin 1 -0.00493807
NRG1 neuregulin 1 -0.00493391
TRIM16 tripartite motif containing 16 -0.00493097
ANXA11 annexin A11 -0.0049156
GOT1 glutamic-oxaloacetic transaminase 1, soluble -0.00491539