AIP Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description aryl hydrocarbon receptor interacting protein|The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] (NCBI Entrez Gene Database, 9049)
External Link http://www.ncbi.nlm.nih.gov/gene/9049
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324 interacting proteins for AIP from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACADVL acyl-CoA dehydrogenase, very long chain
ACBD5 acyl-CoA binding domain containing 5
ACP1 acid phosphatase 1, soluble
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTB actin, beta
ADAP1 ArfGAP with dual PH domains 1
ADD1 adducin 1 (alpha)
ADD3 adducin 3 (gamma)
AFF1 AF4/FMR2 family, member 1
AFF3 AF4/FMR2 family, member 3
AFF4 AF4/FMR2 family, member 4
AGO1 argonaute RISC catalytic component 1
AGPS alkylglycerone phosphate synthase
AHNAK AHNAK nucleoprotein
AHR aryl hydrocarbon receptor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKRD28 ankyrin repeat domain 28
ANKRD44 ankyrin repeat domain 44
ANKRD52 ankyrin repeat domain 52
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARCN1 archain 1
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARF6 ADP-ribosylation factor 6
ARHGAP1 Rho GTPase activating protein 1
ARHGAP8 Rho GTPase activating protein 8
ARL1 ADP-ribosylation factor-like 1
ARNT aryl hydrocarbon receptor nuclear translocator
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AURKB aurora kinase B
B3GAT3 beta-1,3-glucuronyltransferase 3
BAG3 BCL2-associated athanogene 3
BZW1 basic leucine zipper and W2 domains 1
BZW2 basic leucine zipper and W2 domains 2
CACYBP calcyclin binding protein
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CCDC117 coiled-coil domain containing 117
CCDC47 coiled-coil domain containing 47
CCNT1 cyclin T1
CCNT2 cyclin T2
CD9 CD9 molecule
CDC37 cell division cycle 37
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK12 cyclin-dependent kinase 12
CDK15 cyclin-dependent kinase 15
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CEP97 centrosomal protein 97kDa
CFL1 cofilin 1 (non-muscle)
CHMP2A charged multivesicular body protein 2A
CHMP4B charged multivesicular body protein 4B
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC7A C-type lectin domain family 7, member A
CLIC1 chloride intracellular channel 1
CLTC clathrin, heavy chain (Hc)
CNN2 calponin 2
COPA coatomer protein complex, subunit alpha
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CPT1A carnitine palmitoyltransferase 1A (liver)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTTN cortactin
CUL3 cullin 3
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYTH1 cytohesin 1
CYTH2 cytohesin 2
CYTH3 cytohesin 3
DIAPH1 diaphanous-related formin 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DNM2 dynamin 2
DPCD deleted in primary ciliary dyskinesia homolog (mouse)
DRG1 developmentally regulated GTP binding protein 1
DSTN destrin (actin depolymerizing factor)
DTYMK deoxythymidylate kinase (thymidylate kinase)
DUSP23 dual specificity phosphatase 23
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPCAM epithelial cell adhesion molecule
ERAP1 endoplasmic reticulum aminopeptidase 1
ESYT1 extended synaptotagmin-like protein 1
ETHE1 ethylmalonic encephalopathy 1
FANCI Fanconi anemia, complementation group I
FAR2 fatty acyl CoA reductase 2
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FER fer (fps/fes related) tyrosine kinase
FGFR4 fibroblast growth factor receptor 4
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FKBPL FK506 binding protein like
FLNC filamin C, gamma
FNTA farnesyltransferase, CAAX box, alpha
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G6PD glucose-6-phosphate dehydrogenase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBAS glioblastoma amplified sequence
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GDI2 GDP dissociation inhibitor 2
GLMN glomulin, FKBP associated protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNPAT glyceronephosphate O-acyltransferase
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HEXIM1 hexamethylene bis-acetamide inducible 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-H major histocompatibility complex, class I, H (pseudogene)
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSDL2 hydroxysteroid dehydrogenase like 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IQGAP1 IQ motif containing GTPase activating protein 1
IQSEC1 IQ motif and Sec7 domain 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRF7 interferon regulatory factor 7
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
KIAA0368 KIAA0368
KIF5B kinesin family member 5B
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP1 lysosomal-associated membrane protein 1
LARP7 La ribonucleoprotein domain family, member 7
LBR lamin B receptor
LDHA lactate dehydrogenase A
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC40 leucine rich repeat containing 40
LRRC59 leucine rich repeat containing 59
LTN1 listerin E3 ubiquitin protein ligase 1
MAGED1 melanoma antigen family D1
MAPK1 mitogen-activated protein kinase 1
MARCKSL1 MARCKS-like 1
MAX MYC associated factor X
MEPCE methylphosphate capping enzyme
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MX1 MX dynamin-like GTPase 1
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYO18A myosin XVIIIA
MYO1E myosin IE
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
NADSYN1 NAD synthetase 1
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRF1 nuclear respiratory factor 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSF N-ethylmaleimide-sensitive factor
NTPCR nucleoside-triphosphatase, cancer-related
NUDC nudC nuclear distribution protein
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUP98 nucleoporin 98kDa
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PALD1 phosphatase domain containing, paladin 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4A phosphodiesterase 4A, cAMP-specific
PDS5A PDS5 cohesin associated factor A
PDZD8 PDZ domain containing 8
PFDN2 prefoldin subunit 2
PFDN5 prefoldin subunit 5
PFDN6 prefoldin subunit 6
PFKL phosphofructokinase, liver
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PHB prohibitin
PHGDH phosphoglycerate dehydrogenase
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PITPNB phosphatidylinositol transfer protein, beta
PKM pyruvate kinase, muscle
PKN2 protein kinase N2
PLEK2 pleckstrin 2
PLK1 polo-like kinase 1
PLLP plasmolipin
PLS1 plastin 1
POTEE POTE ankyrin domain family, member E
PPARA peroxisome proliferator-activated receptor alpha
PPID peptidylprolyl isomerase D
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP5C protein phosphatase 5, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PPP6R1 protein phosphatase 6, regulatory subunit 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB11A RAB11A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAE1 ribonucleic acid export 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
REPS1 RALBP1 associated Eps domain containing 1
RHEB Ras homolog enriched in brain
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPAP3 RNA polymerase II associated protein 3
RPN1 ribophorin I
RPN2 ribophorin II
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRAS related RAS viral (r-ras) oncogene homolog
RSU1 Ras suppressor protein 1
RUVBL2 RuvB-like AAA ATPase 2
SAR1A secretion associated, Ras related GTPase 1A
SARNP SAP domain containing ribonucleoprotein
SCCPDH saccharopine dehydrogenase (putative)
SCP2 sterol carrier protein 2
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEPT11 septin 11
SEPT2 septin 2
SEPT7 septin 7
SEPT9 septin 9
SFXN1 sideroflexin 1
SGPL1 sphingosine-1-phosphate lyase 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIM2 single-minded family bHLH transcription factor 2
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SMYD3 SET and MYND domain containing 3
SNAPIN SNAP-associated protein
SNX5 sorting nexin 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SQRDL sulfide quinone reductase-like (yeast)
SRP54 signal recognition particle 54kDa
SRP72 signal recognition particle 72kDa
SRP9 signal recognition particle 9kDa
SRPK1 SRSF protein kinase 1
SSRP1 structure specific recognition protein 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STIP1 stress-induced phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STXBP5 syntaxin binding protein 5 (tomosyn)
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SYNE2 spectrin repeat containing, nuclear envelope 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAGLN2 transgelin 2
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D4 TBC1 domain family, member 4
TCAF1 TRPM8 channel-associated factor 1
TFRC transferrin receptor
TLK2 tousled-like kinase 2
TLN1 talin 1
TMEM109 transmembrane protein 109
TMEM33 transmembrane protein 33
TMOD2 tropomodulin 2 (neuronal)
TMOD3 tropomodulin 3 (ubiquitous)
TMOD4 tropomodulin 4 (muscle)
TNNI3K TNNI3 interacting kinase
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOMM34 translocase of outer mitochondrial membrane 34
TPD52 tumor protein D52
TPD52L2 tumor protein D52-like 2
TPM3 tropomyosin 3
TRAP1 TNF receptor-associated protein 1
TRIM28 tripartite motif containing 28
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMT61B tRNA methyltransferase 61B
TSPAN8 tetraspanin 8
TTC1 tetratricopeptide repeat domain 1
TTC39B tetratricopeptide repeat domain 39B
TTC4 tetratricopeptide repeat domain 4
TTC9C tetratricopeptide repeat domain 9C
TUBA1A tubulin, alpha 1a
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
UCK2 uridine-cytidine kinase 2
UNC45A unc-45 homolog A (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
URI1 URI1, prefoldin-like chaperone
USP19 ubiquitin specific peptidase 19
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VSNL1 visinin-like 1
VTA1 vesicle (multivesicular body) trafficking 1
WDR92 WD repeat domain 92
WIPI2 WD repeat domain, phosphoinositide interacting 2
XPO1 exportin 1
XPO7 exportin 7
ZC3H15 zinc finger CCCH-type containing 15