| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | autoimmune regulator|This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012] (NCBI Entrez Gene Database, 326) |
| External Link | https://ncbi.nlm.nih.gov/gene/326 |
| Similar Terms | |
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499 genes differentially expressed following the AIRE gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGEA3 | melanoma antigen family A3 | 0.0149848 |
| GNAS | GNAS complex locus | 0.0149281 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0140463 |
| ALB | albumin | 0.0139444 |
| SIRT3 | sirtuin 3 | 0.0131609 |
| KRT15 | keratin 15, type I | 0.0120608 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0119534 |
| A2M | alpha-2-macroglobulin | 0.0117599 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0117546 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0114965 |
| KRT14 | keratin 14, type I | 0.0112919 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0111994 |
| POU2AF1 | POU class 2 associating factor 1 | 0.0111403 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.011042 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0105614 |
| FGB | fibrinogen beta chain | 0.0104381 |
| PLS3 | plastin 3 | 0.00955718 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00943227 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00941824 |
| CFI | complement factor I | 0.00939996 |
| FGG | fibrinogen gamma chain | 0.00908635 |
| MAGEA12 | melanoma antigen family A12 | 0.00889978 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00879378 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00874744 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00871611 |
| ASPN | asporin | 0.00866116 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00865805 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00863841 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00847121 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00833318 |
| XPO7 | exportin 7 | 0.00832844 |
| MSX1 | msh homeobox 1 | 0.00823946 |
| APOB | apolipoprotein B | 0.00821383 |
| NID1 | nidogen 1 | 0.00818834 |
| ANXA1 | annexin A1 | 0.00817377 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00816219 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00815463 |
| ARG2 | arginase 2 | 0.00808441 |
| STC1 | stanniocalcin 1 | 0.00808175 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00802011 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00788012 |
| FGA | fibrinogen alpha chain | 0.00778573 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00775506 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00773596 |
| CD93 | CD93 molecule | 0.00771526 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.0076473 |
| NCOA2 | nuclear receptor coactivator 2 | 0.00758705 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00754905 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00753732 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00751405 |
| STAT5B | signal transducer and activator of transcription 5B | 0.00751338 |
| C1S | complement component 1, s subcomponent | 0.00750373 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00718547 |
| EMP1 | epithelial membrane protein 1 | 0.0071788 |
| RGS5 | regulator of G-protein signaling 5 | 0.00714312 |
| MME | membrane metallo-endopeptidase | 0.00709024 |
| DEFB1 | defensin, beta 1 | 0.00707115 |
| INSR | insulin receptor | 0.00701954 |
| MST1 | macrophage stimulating 1 | 0.00701614 |
| BTG3 | BTG family, member 3 | 0.00700247 |
| ELMO1 | engulfment and cell motility 1 | 0.00699164 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00699117 |
| TTR | transthyretin | 0.00695247 |
| ORM1 | orosomucoid 1 | 0.00692942 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00692619 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00688931 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0068681 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00686499 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00683076 |
| NRN1 | neuritin 1 | 0.00682937 |
| KRT5 | keratin 5, type II | 0.00679413 |
| EGR1 | early growth response 1 | 0.00676973 |
| LAMB1 | laminin, beta 1 | 0.00676775 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00676248 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00675767 |
| MT1X | metallothionein 1X | 0.00675102 |
| MXRA5 | matrix-remodelling associated 5 | 0.00670964 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00670119 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00668951 |
| RREB1 | ras responsive element binding protein 1 | 0.00665372 |
| BRD4 | bromodomain containing 4 | 0.00661909 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00658449 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00657378 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00655993 |
| R3HDM4 | R3H domain containing 4 | 0.00655204 |
| AIM2 | absent in melanoma 2 | 0.00654742 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00650793 |
| SELENBP1 | selenium binding protein 1 | 0.00647677 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.0064561 |
| PRAME | preferentially expressed antigen in melanoma | 0.0063936 |
| C3 | complement component 3 | 0.00639285 |
| OLFM4 | olfactomedin 4 | 0.00638382 |
| RCAN1 | regulator of calcineurin 1 | 0.00635217 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00630504 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00629694 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00628987 |
| FBLN1 | fibulin 1 | 0.00627691 |
| CTSB | cathepsin B | 0.00626836 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00626264 |
| INHBB | inhibin, beta B | 0.00622044 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00621011 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00620703 |
| AEBP1 | AE binding protein 1 | 0.00620231 |
| PEG10 | paternally expressed 10 | 0.00620215 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00620121 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00616516 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00616084 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00615208 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00612943 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00607294 |
| PLXND1 | plexin D1 | 0.00605892 |
| FOXO1 | forkhead box O1 | 0.0060204 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00600979 |
| MAGEA1 | melanoma antigen family A1 | 0.00600614 |
| MMP11 | matrix metallopeptidase 11 | 0.00598439 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00596634 |
| ENAH | enabled homolog (Drosophila) | 0.00596569 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00596264 |
| FAM189A2 | family with sequence similarity 189, member A2 | 0.00594257 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00593187 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.00587999 |
| RGCC | regulator of cell cycle | 0.00587141 |
| TMEM176B | transmembrane protein 176B | 0.00585848 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00583662 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | 0.00583225 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00580169 |
| FABP1 | fatty acid binding protein 1, liver | 0.0057872 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00578219 |
| FKBP5 | FK506 binding protein 5 | 0.0057774 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00577535 |
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 | 0.00577041 |
| PLXNA1 | plexin A1 | 0.00576785 |
| FLT1 | fms-related tyrosine kinase 1 | 0.00575174 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00572702 |
| CD200 | CD200 molecule | 0.0057232 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | 0.00571874 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00571523 |
| C1R | complement component 1, r subcomponent | 0.00571365 |
| PER1 | period circadian clock 1 | 0.00571279 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00566329 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00565282 |
| CPB2 | carboxypeptidase B2 (plasma) | 0.00563943 |
| WDR45 | WD repeat domain 45 | 0.00562995 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00562074 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00561496 |
| BSG | basigin (Ok blood group) | 0.0056137 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00560759 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00560583 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00558754 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0055594 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00553972 |
| FGF9 | fibroblast growth factor 9 | 0.00553364 |
| KRT18 | keratin 18, type I | 0.00553051 |
| NAV2 | neuron navigator 2 | 0.00552621 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00550588 |
| RHCG | Rh family, C glycoprotein | 0.00548672 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | 0.00547867 |
| EGR3 | early growth response 3 | 0.00547481 |
| APOA2 | apolipoprotein A-II | 0.00547148 |
| CCNA2 | cyclin A2 | 0.00545788 |
| SPRR1B | small proline-rich protein 1B | 0.0054467 |
| DBN1 | drebrin 1 | 0.00543237 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00543062 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00542562 |
| PTN | pleiotrophin | 0.00542129 |
| CHN1 | chimerin 1 | 0.00540815 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00539346 |
| STC2 | stanniocalcin 2 | 0.00538498 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00533794 |
| MT2A | metallothionein 2A | 0.00533679 |
| MAGEA4 | melanoma antigen family A4 | 0.00533319 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00532576 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00531427 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00531245 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00530866 |
| ERGIC2 | ERGIC and golgi 2 | 0.00530541 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 0.00530027 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00529743 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00526151 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00525667 |
| FBLN2 | fibulin 2 | 0.00524435 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00523267 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00523044 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00522946 |
| METTL7A | methyltransferase like 7A | 0.00522619 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00519473 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00519208 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00518922 |
| CNN3 | calponin 3, acidic | 0.00518353 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0051828 |
| G0S2 | G0/G1 switch 2 | 0.00517263 |
| TSPAN7 | tetraspanin 7 | 0.00516995 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00515218 |
| ADIPOR2 | adiponectin receptor 2 | 0.00514927 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00513416 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00512164 |
| ATF3 | activating transcription factor 3 | 0.00511534 |
| PDE8B | phosphodiesterase 8B | 0.00510653 |
| AQP9 | aquaporin 9 | 0.00509864 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0050969 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0050889 |
| IL27RA | interleukin 27 receptor, alpha | 0.00506605 |
| KRT6B | keratin 6B, type II | 0.00505654 |
| CD53 | CD53 molecule | 0.00504974 |
| PNMA8A | PNMA family member 8A | 0.00503852 |
| KLF13 | Kruppel-like factor 13 | 0.00503762 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.00502217 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00502027 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.00501595 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00501274 |
| PLTP | phospholipid transfer protein | 0.00500869 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00500541 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00500174 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00499751 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00499559 |
| ZNF281 | zinc finger protein 281 | 0.00499537 |
| VEGFA | vascular endothelial growth factor A | 0.00499405 |
| PLIN1 | perilipin 1 | 0.00499384 |
| PCBP2 | poly(rC) binding protein 2 | 0.00499213 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0049898 |
| GSDMB | gasdermin B | 0.0049888 |
| BMP2 | bone morphogenetic protein 2 | 0.00498069 |
| LAMB3 | laminin, beta 3 | 0.00495711 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00494872 |
| KLF2 | Kruppel-like factor 2 | 0.00494765 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00494515 |
| AOC3 | amine oxidase, copper containing 3 | 0.00494317 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.0049393 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00492555 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0049154 |
| GOLM1 | golgi membrane protein 1 | 0.00491312 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.00491163 |
| PCDH17 | protocadherin 17 | 0.00490566 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00489832 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00489721 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00489561 |
| APOC3 | apolipoprotein C-III | 0.0048934 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00488805 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00488767 |
| PLVAP | plasmalemma vesicle associated protein | 0.00488733 |
| PLAU | plasminogen activator, urokinase | 0.00487867 |
| CP | ceruloplasmin (ferroxidase) | 0.00486972 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | 0.00485767 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | 0.00484495 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00483439 |
| PNN | pinin, desmosome associated protein | 0.00482853 |
| STXBP2 | syntaxin binding protein 2 | 0.00482737 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00482415 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.0048233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0268899 |
| S100P | S100 calcium binding protein P | -0.0150638 |
| SLC44A4 | solute carrier family 44, member 4 | -0.014735 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0123124 |
| PROM1 | prominin 1 | -0.0106737 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0106267 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0105838 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.0105768 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0104505 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0103499 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0103004 |
| HOPX | HOP homeobox | -0.00993704 |
| GPM6A | glycoprotein M6A | -0.00967942 |
| KAZN | kazrin, periplakin interacting protein | -0.00963719 |
| REEP1 | receptor accessory protein 1 | -0.00958332 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00956661 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.00938689 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0091795 |
| MB | myoglobin | -0.00917053 |
| LYZ | lysozyme | -0.00914797 |
| ANXA3 | annexin A3 | -0.00910318 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00909757 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00903842 |
| HBD | hemoglobin, delta | -0.00882289 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00861764 |
| COG7 | component of oligomeric golgi complex 7 | -0.00850555 |
| TTN | titin | -0.0083488 |
| NEFH | neurofilament, heavy polypeptide | -0.00833099 |
| TSPAN1 | tetraspanin 1 | -0.00829193 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00823535 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00819126 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00816524 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00814457 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00808785 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00807462 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00800961 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00798607 |
| TSPAN12 | tetraspanin 12 | -0.00798077 |
| TMEM47 | transmembrane protein 47 | -0.00797265 |
| NAV3 | neuron navigator 3 | -0.00795246 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00780661 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00779159 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00769142 |
| ZNF652 | zinc finger protein 652 | -0.00754833 |
| NPTX2 | neuronal pentraxin II | -0.00754323 |
| HIST3H2A | histone cluster 3, H2a | -0.00751734 |
| NTS | neurotensin | -0.00740476 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00737428 |
| GATA6 | GATA binding protein 6 | -0.00734986 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00732696 |
| RTN2 | reticulon 2 | -0.00725792 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00722428 |
| TOX3 | TOX high mobility group box family member 3 | -0.00722257 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00718983 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00718646 |
| PUDP | pseudouridine 5'-phosphatase | -0.00715358 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00712435 |
| DACH1 | dachshund family transcription factor 1 | -0.0071049 |
| THBS1 | thrombospondin 1 | -0.00708071 |
| CSTA | cystatin A (stefin A) | -0.0070648 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00705658 |
| CKM | creatine kinase, muscle | -0.00702868 |
| SPAG16 | sperm associated antigen 16 | -0.00694941 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00693153 |
| TFF1 | trefoil factor 1 | -0.00691663 |
| DIXDC1 | DIX domain containing 1 | -0.00689407 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00688382 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00687592 |
| NME5 | NME/NM23 family member 5 | -0.00686451 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00685159 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00679803 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0067874 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00676087 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00675304 |
| MLF1 | myeloid leukemia factor 1 | -0.00673226 |
| AHI1 | Abelson helper integration site 1 | -0.00669769 |
| AGR2 | anterior gradient 2 | -0.00669387 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00668936 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.0066573 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | -0.00665238 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00665064 |
| NOTCH2NL | notch 2 N-terminal like | -0.00662034 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00662008 |
| SLN | sarcolipin | -0.00661863 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00659137 |
| GALC | galactosylceramidase | -0.00658826 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00655136 |
| TSPAN13 | tetraspanin 13 | -0.00653586 |
| AHR | aryl hydrocarbon receptor | -0.00649596 |
| GUCY2C | guanylate cyclase 2C | -0.00648681 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00648271 |
| AQP4 | aquaporin 4 | -0.00641183 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00640982 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00640408 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00637834 |
| IRX5 | iroquois homeobox 5 | -0.00635197 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00630936 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00629928 |
| DES | desmin | -0.00629646 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00627751 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00626725 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00622034 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00618846 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | -0.0061849 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00618282 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00615614 |
| THAP10 | THAP domain containing 10 | -0.00615185 |
| HNMT | histamine N-methyltransferase | -0.00613334 |
| ZNF91 | zinc finger protein 91 | -0.00609396 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00606466 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00606267 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00605275 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00601687 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00598829 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00595911 |
| KRT10 | keratin 10, type I | -0.00587806 |
| PERP | PERP, TP53 apoptosis effector | -0.00584727 |
| RAB32 | RAB32, member RAS oncogene family | -0.00583545 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00579767 |
| CRIP2 | cysteine-rich protein 2 | -0.00579652 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.0057907 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00578798 |
| NPR3 | natriuretic peptide receptor 3 | -0.00577833 |
| SPAG1 | sperm associated antigen 1 | -0.00575374 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00575256 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00574252 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -0.00573353 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0056853 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00568239 |
| ZNF468 | zinc finger protein 468 | -0.00567984 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.00565836 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00563593 |
| BIN1 | bridging integrator 1 | -0.0056337 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.0056286 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0056145 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00561409 |
| TNNC1 | troponin C type 1 (slow) | -0.00560764 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00560428 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00560184 |
| MEIS1 | Meis homeobox 1 | -0.00559731 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0055851 |
| TNNC2 | troponin C type 2 (fast) | -0.00558272 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | -0.00557889 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00557881 |
| UPK1B | uroplakin 1B | -0.00556645 |
| EDF1 | endothelial differentiation-related factor 1 | -0.00556619 |
| PEG3 | paternally expressed 3 | -0.00555707 |
| DAPK1 | death-associated protein kinase 1 | -0.00555698 |
| TMEM100 | transmembrane protein 100 | -0.00554194 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | -0.00553949 |
| ACYP2 | acylphosphatase 2, muscle type | -0.00552915 |
| CDC42 | cell division cycle 42 | -0.00552902 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00552026 |
| AZI2 | 5-azacytidine induced 2 | -0.00552019 |
| INSM1 | insulinoma-associated 1 | -0.00550855 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -0.00549807 |
| CRYM | crystallin, mu | -0.00548224 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00548038 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00546277 |
| EFNB2 | ephrin-B2 | -0.0054608 |
| PEX7 | peroxisomal biogenesis factor 7 | -0.0054586 |
| QKI | QKI, KH domain containing, RNA binding | -0.00544895 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00542533 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00541477 |
| PSPH | phosphoserine phosphatase | -0.00541043 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0053812 |
| PIR | pirin (iron-binding nuclear protein) | -0.00535385 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00534851 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00531273 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | -0.0053031 |
| ASRGL1 | asparaginase like 1 | -0.00530255 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00529259 |
| GLCE | glucuronic acid epimerase | -0.00526074 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00525164 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.0052478 |
| EPHB2 | EPH receptor B2 | -0.00524284 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G | -0.0052423 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00524016 |
| KLK6 | kallikrein-related peptidase 6 | -0.00523977 |
| C9ORF116 | chromosome 9 open reading frame 116 | -0.00523576 |
| CLU | clusterin | -0.00522789 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.00522689 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00522034 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00521205 |
| KLF3-AS1 | KLF3 antisense RNA 1 | -0.00520709 |
| TMEM231 | transmembrane protein 231 | -0.0052052 |
| NDNF | neuron-derived neurotrophic factor | -0.00516201 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.0051515 |
| CMC2 | C-x(9)-C motif containing 2 | -0.00514634 |
| ITM2A | integral membrane protein 2A | -0.00514554 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.00514244 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00513347 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.00513297 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00512384 |
| KLHL41 | kelch-like family member 41 | -0.00512157 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.00511878 |
| S100A4 | S100 calcium binding protein A4 | -0.00511732 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | -0.00511315 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00511224 |
| ACTN2 | actinin, alpha 2 | -0.00510764 |
| CD1E | CD1e molecule | -0.00510654 |
| ANOS1 | anosmin 1 | -0.00510048 |
| TCF21 | transcription factor 21 | -0.00510045 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00508855 |
| SELENOT | selenoprotein T | -0.00507472 |
| COMT | catechol-O-methyltransferase | -0.00507222 |
| CHODL | chondrolectin | -0.00506483 |
| RPS5 | ribosomal protein S5 | -0.00505701 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00505533 |
| EMX2 | empty spiracles homeobox 2 | -0.00504945 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00502268 |
| COMMD8 | COMM domain containing 8 | -0.00501803 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00501613 |
| CHGB | chromogranin B | -0.00501369 |
| KIAA0895 | KIAA0895 | -0.00501321 |
| ZNF593 | zinc finger protein 593 | -0.00501008 |
| MYOT | myotilin | -0.00500768 |
| MANSC1 | MANSC domain containing 1 | -0.0049932 |
| PYCARD | PYD and CARD domain containing | -0.00499309 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00499052 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.00498357 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0049832 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00498071 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | -0.00497872 |
| NNMT | nicotinamide N-methyltransferase | -0.00497849 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00497685 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00496316 |
| TRIM16 | tripartite motif containing 16 | -0.00496186 |
| PRKCZ | protein kinase C, zeta | -0.00495162 |
| ENO3 | enolase 3 (beta, muscle) | -0.00493761 |
| GPX2 | glutathione peroxidase 2 | -0.00492846 |
| SIX2 | SIX homeobox 2 | -0.00492794 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | -0.00492697 |
| TSPAN6 | tetraspanin 6 | -0.00492262 |
| TFEC | transcription factor EC | -0.00492129 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00491989 |
| ZNF329 | zinc finger protein 329 | -0.00491795 |
| SMPX | small muscle protein, X-linked | -0.00491638 |
| MYBPC2 | myosin binding protein C, fast type | -0.0049151 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00491046 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00490743 |
| GRHL2 | grainyhead-like 2 (Drosophila) | -0.00490468 |
| YME1L1 | YME1-like 1 ATPase | -0.00489803 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00487672 |
| OSMR | oncostatin M receptor | -0.00486851 |
| ZNF226 | zinc finger protein 226 | -0.00486719 |
| CCL15 | chemokine (C-C motif) ligand 15 | -0.0048568 |
| SPATA7 | spermatogenesis associated 7 | -0.00485376 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00484669 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00484498 |
