| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | adenylate kinase 2|Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010] (NCBI Entrez Gene Database, 204) |
| External Link | https://ncbi.nlm.nih.gov/gene/204 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the AK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0185697 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0149464 |
| MMP7 | matrix metallopeptidase 7 | 0.0122019 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0114712 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0112903 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.0112869 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0111386 |
| S100A7 | S100 calcium binding protein A7 | 0.0109605 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.0109286 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0107688 |
| LTF | lactotransferrin | 0.0104744 |
| S100A8 | S100 calcium binding protein A8 | 0.0102985 |
| TPM2 | tropomyosin 2 (beta) | 0.0102916 |
| SIRT3 | sirtuin 3 | 0.0100989 |
| CFB | complement factor B | 0.0100471 |
| IL7R | interleukin 7 receptor | 0.01001 |
| SORD | sorbitol dehydrogenase | 0.00996387 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00990669 |
| ACP3 | acid phosphatase 3 | 0.00983703 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00910193 |
| KAZN | kazrin, periplakin interacting protein | 0.0090521 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00900909 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00900777 |
| GPX1 | glutathione peroxidase 1 | 0.00898331 |
| MB | myoglobin | 0.00895814 |
| GMPR | guanosine monophosphate reductase | 0.00863489 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00859309 |
| S100A2 | S100 calcium binding protein A2 | 0.00855547 |
| TNC | tenascin C | 0.00839617 |
| NKX3-1 | NK3 homeobox 1 | 0.00837392 |
| FSTL1 | follistatin-like 1 | 0.00836984 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00835965 |
| MCOLN1 | mucolipin 1 | 0.00833134 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00825923 |
| NPTXR | neuronal pentraxin receptor | 0.00820023 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00815862 |
| KRT5 | keratin 5, type II | 0.00807087 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00804953 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00801372 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00800782 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.00800074 |
| DUSP3 | dual specificity phosphatase 3 | 0.00795109 |
| S100A9 | S100 calcium binding protein A9 | 0.00793826 |
| MYBPC1 | myosin binding protein C, slow type | 0.00792763 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00792202 |
| CLDN3 | claudin 3 | 0.00786376 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.0078292 |
| BIN1 | bridging integrator 1 | 0.00781813 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00781735 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00768348 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00768255 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00766216 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00760804 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00757792 |
| MMP10 | matrix metallopeptidase 10 | 0.00751131 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00746071 |
| RANBP1 | RAN binding protein 1 | 0.00744748 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00741927 |
| SELL | selectin L | 0.00737819 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00735644 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00733886 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00732376 |
| IFI44L | interferon-induced protein 44-like | 0.00723196 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00721156 |
| TBX3 | T-box 3 | 0.00719389 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00709116 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00704683 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00703966 |
| COG7 | component of oligomeric golgi complex 7 | 0.00700027 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00699898 |
| GPX4 | glutathione peroxidase 4 | 0.00695172 |
| COL1A2 | collagen, type I, alpha 2 | 0.0069515 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0069305 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00688883 |
| IL1RN | interleukin 1 receptor antagonist | 0.00687543 |
| TRIB2 | tribbles pseudokinase 2 | 0.00686377 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00682899 |
| A2M | alpha-2-macroglobulin | 0.00682142 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00678079 |
| COL5A1 | collagen, type V, alpha 1 | 0.00677151 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00675052 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00667302 |
| LST1 | leukocyte specific transcript 1 | 0.00665833 |
| CLCA2 | chloride channel accessory 2 | 0.00665043 |
| RAB20 | RAB20, member RAS oncogene family | 0.00660986 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0066076 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00658927 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00654664 |
| NPY | neuropeptide Y | 0.00654434 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00650231 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00647815 |
| NTS | neurotensin | 0.00647782 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00645599 |
| KLK3 | kallikrein-related peptidase 3 | 0.00645281 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00643697 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00637498 |
| MSMB | microseminoprotein, beta- | 0.00634361 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00633214 |
| CCN2 | cellular communication network factor 2 | 0.00632439 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.006318 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00628998 |
| USP18 | ubiquitin specific peptidase 18 | 0.00628341 |
| TARP | TCR gamma alternate reading frame protein | 0.00626666 |
| ABHD11 | abhydrolase domain containing 11 | 0.00625799 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00625487 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00618399 |
| PRF1 | perforin 1 (pore forming protein) | 0.00617835 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00617224 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00616766 |
| FOXC1 | forkhead box C1 | 0.00615167 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00613744 |
| POR | P450 (cytochrome) oxidoreductase | 0.00613665 |
| PRDX2 | peroxiredoxin 2 | 0.00611726 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00611611 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.00610346 |
| EMD | emerin | 0.00609097 |
| MARCKSL1 | MARCKS-like 1 | 0.00605717 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00602941 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00600364 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00598513 |
| KLK2 | kallikrein-related peptidase 2 | 0.00598113 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00597525 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00597 |
| MANSC1 | MANSC domain containing 1 | 0.00596834 |
| TSPAN4 | tetraspanin 4 | 0.0059102 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0059025 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.00590059 |
| EPHB4 | EPH receptor B4 | 0.00585063 |
| TNS3 | tensin 3 | 0.00584155 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00583407 |
| NDRG3 | NDRG family member 3 | 0.00582447 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00580724 |
| RPN2 | ribophorin II | 0.00579602 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00579322 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00578905 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00577139 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00576784 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00575863 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00575554 |
| GM2A | GM2 ganglioside activator | 0.00574667 |
| R3HDM2 | R3H domain containing 2 | 0.00574056 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00573584 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00573282 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00572436 |
| CLEC4A | C-type lectin domain family 4, member A | 0.005716 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00571287 |
| HBD | hemoglobin, delta | 0.00569998 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.00569396 |
| PON2 | paraoxonase 2 | 0.00568572 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00567863 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00567482 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.00567176 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00566123 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00565419 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00565398 |
| NKG7 | natural killer cell granule protein 7 | 0.00565091 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00563382 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00563213 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00560317 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00559657 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00558809 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00558789 |
| KIAA0100 | KIAA0100 | 0.00558297 |
| STOM | stomatin | 0.00556535 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00554642 |
| CD52 | CD52 molecule | 0.00554292 |
| UBE2M | ubiquitin-conjugating enzyme E2M | 0.00553996 |
| KRT17 | keratin 17, type I | 0.00553748 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00551775 |
| LCN2 | lipocalin 2 | 0.0055091 |
| MMP1 | matrix metallopeptidase 1 | 0.00550279 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00549159 |
| RBM38 | RNA binding motif protein 38 | 0.00548094 |
| YBX3 | Y box binding protein 3 | 0.00545544 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00544915 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | 0.00544566 |
| TRIM14 | tripartite motif containing 14 | 0.00543245 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.00542956 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00540999 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00539671 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00539511 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.00538526 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.0053811 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00537554 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00537047 |
| RPL36 | ribosomal protein L36 | 0.00534987 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00533708 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | 0.00533149 |
| MLPH | melanophilin | 0.00532813 |
| WASHC4 | WASH complex subunit 4 | 0.00532466 |
| IL2RB | interleukin 2 receptor, beta | 0.00531599 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00530778 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.00529129 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00527799 |
| BLVRB | biliverdin reductase B | 0.00526663 |
| CSTB | cystatin B (stefin B) | 0.0052643 |
| MICB | MHC class I polypeptide-related sequence B | 0.00525879 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00525336 |
| KYNU | kynureninase | 0.00524872 |
| PHF11 | PHD finger protein 11 | 0.00522246 |
| FUS | FUS RNA binding protein | 0.00522208 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00522197 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.00521854 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.0052134 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 | 0.00520042 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0051917 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00518094 |
| NNMT | nicotinamide N-methyltransferase | 0.0051734 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00516462 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 0.00515169 |
| SCARA3 | scavenger receptor class A, member 3 | 0.00514535 |
| LOXL1 | lysyl oxidase-like 1 | 0.00514386 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 0.00513366 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00512294 |
| HDAC3 | histone deacetylase 3 | 0.00509701 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00508988 |
| GNLY | granulysin | 0.00508645 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00507908 |
| VCL | vinculin | 0.00507778 |
| RPIA | ribose 5-phosphate isomerase A | 0.00505656 |
| SHTN1 | shootin 1 | 0.00505521 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | 0.00505274 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00505068 |
| CHKB | choline kinase beta | 0.0050504 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00503955 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00503783 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.00502727 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00502529 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.0050083 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00500039 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00499358 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0049889 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00498784 |
| DEAF1 | DEAF1 transcription factor | 0.00498568 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00498181 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00497555 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0049745 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00497248 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00496732 |
| GLO1 | glyoxalase I | 0.0049654 |
| SLAMF7 | SLAM family member 7 | 0.00495782 |
| TRIM38 | tripartite motif containing 38 | 0.00495448 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00494417 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00494263 |
| RAB13 | RAB13, member RAS oncogene family | 0.0049425 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00492716 |
| KIF20A | kinesin family member 20A | 0.00492634 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.00492591 |
| RPS5 | ribosomal protein S5 | 0.00492573 |
| SOAT1 | sterol O-acyltransferase 1 | 0.00492362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POSTN | periostin, osteoblast specific factor | -0.0125607 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0119905 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0112164 |
| RGS5 | regulator of G-protein signaling 5 | -0.0108212 |
| CA12 | carbonic anhydrase XII | -0.0104622 |
| RGCC | regulator of cell cycle | -0.0103219 |
| TAC1 | tachykinin, precursor 1 | -0.0101001 |
| TSPAN7 | tetraspanin 7 | -0.00995159 |
| NRCAM | neuronal cell adhesion molecule | -0.00979377 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00968901 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00958051 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00956238 |
| PENK | proenkephalin | -0.00943717 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00934884 |
| BMP2 | bone morphogenetic protein 2 | -0.00887962 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00886792 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00881627 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00879037 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00874005 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00868745 |
| CDC42 | cell division cycle 42 | -0.00866846 |
| CALB1 | calbindin 1, 28kDa | -0.00863113 |
| TMEM176B | transmembrane protein 176B | -0.00855266 |
| ANK2 | ankyrin 2, neuronal | -0.00845587 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00838406 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00838206 |
| MEN1 | multiple endocrine neoplasia I | -0.00831852 |
| STMN2 | stathmin 2 | -0.00825977 |
| OLFML2A | olfactomedin-like 2A | -0.00825934 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00817566 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00813502 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00811714 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00810055 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00809428 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00805453 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00804806 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00803761 |
| ANGPT2 | angiopoietin 2 | -0.00802497 |
| CALCA | calcitonin-related polypeptide alpha | -0.00802406 |
| FCGBP | Fc fragment of IgG binding protein | -0.00802081 |
| BEX1 | brain expressed, X-linked 1 | -0.00792762 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00791982 |
| MIR22HG | MIR22 host gene | -0.00776848 |
| THBS2 | thrombospondin 2 | -0.00775811 |
| FRY | furry homolog (Drosophila) | -0.00769456 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00762078 |
| GPM6A | glycoprotein M6A | -0.00761724 |
| FASTKD5 | FAST kinase domains 5 | -0.00755223 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00753012 |
| SYT11 | synaptotagmin XI | -0.00749662 |
| AHNAK | AHNAK nucleoprotein | -0.00748468 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00747784 |
| NEFM | neurofilament, medium polypeptide | -0.00746215 |
| KRT19 | keratin 19, type I | -0.00738941 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00735545 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00728658 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.00728161 |
| CFH | complement factor H | -0.00724825 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0072071 |
| GAP43 | growth associated protein 43 | -0.00715286 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00714875 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00704975 |
| GPR88 | G protein-coupled receptor 88 | -0.0070461 |
| PMP2 | peripheral myelin protein 2 | -0.00704004 |
| PLSCR4 | phospholipid scramblase 4 | -0.00702425 |
| USP3 | ubiquitin specific peptidase 3 | -0.00700126 |
| FLT1 | fms-related tyrosine kinase 1 | -0.00698698 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.00694424 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00693959 |
| CLTB | clathrin, light chain B | -0.00692491 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0069057 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00685815 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.0068353 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00681694 |
| KLF6 | Kruppel-like factor 6 | -0.00681678 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00678579 |
| RELN | reelin | -0.00678037 |
| DCX | doublecortin | -0.00673307 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00670072 |
| KLF9 | Kruppel-like factor 9 | -0.00668879 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00666479 |
| NKX2-1 | NK2 homeobox 1 | -0.0066399 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.0066324 |
| PODXL | podocalyxin-like | -0.00662499 |
| GMFG | glia maturation factor, gamma | -0.00660614 |
| MGP | matrix Gla protein | -0.00659783 |
| EGR1 | early growth response 1 | -0.00659184 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00658252 |
| BMP7 | bone morphogenetic protein 7 | -0.00657229 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00656967 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00655083 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00652696 |
| HMOX1 | heme oxygenase 1 | -0.00652441 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00648383 |
| AEBP1 | AE binding protein 1 | -0.00648357 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | -0.00645746 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00644559 |
| ACKR3 | atypical chemokine receptor 3 | -0.0064176 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.00641673 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00640009 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00639376 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0063773 |
| GSK3B | glycogen synthase kinase 3 beta | -0.00636664 |
| JAM2 | junctional adhesion molecule 2 | -0.00631492 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00630634 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00630484 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00630024 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00629065 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00628575 |
| MAOA | monoamine oxidase A | -0.00628295 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.00627463 |
| PLCE1 | phospholipase C, epsilon 1 | -0.00627107 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00626544 |
| PLXNA2 | plexin A2 | -0.00625489 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00621651 |
| CALCRL | calcitonin receptor-like | -0.00621034 |
| MRPL22 | mitochondrial ribosomal protein L22 | -0.00619106 |
| PDE10A | phosphodiesterase 10A | -0.00617913 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00617355 |
| KIF1A | kinesin family member 1A | -0.00611525 |
| MAGEA3 | melanoma antigen family A3 | -0.00609196 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00608855 |
| DMD | dystrophin | -0.0060693 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00605839 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00605412 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00605408 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00604468 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00604215 |
| BTG2 | BTG family, member 2 | -0.00603826 |
| CHMP2B | charged multivesicular body protein 2B | -0.00603222 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00601158 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00600513 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00599958 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00599009 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.0059797 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00597183 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00596251 |
| SST | somatostatin | -0.00595524 |
| CA4 | carbonic anhydrase IV | -0.0059503 |
| TMEM176A | transmembrane protein 176A | -0.00590722 |
| MEX3C | mex-3 RNA binding family member C | -0.00588908 |
| ZNF281 | zinc finger protein 281 | -0.00588065 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.0058787 |
| PLCL2 | phospholipase C-like 2 | -0.0058161 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.00581236 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00580824 |
| GCH1 | GTP cyclohydrolase 1 | -0.0058023 |
| FGF9 | fibroblast growth factor 9 | -0.0057901 |
| AZU1 | azurocidin 1 | -0.00578923 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.00578728 |
| PNN | pinin, desmosome associated protein | -0.00577971 |
| HAS1 | hyaluronan synthase 1 | -0.00576165 |
| FABP1 | fatty acid binding protein 1, liver | -0.00575558 |
| ARF6 | ADP-ribosylation factor 6 | -0.00573613 |
| MID1IP1 | MID1 interacting protein 1 | -0.00572531 |
| MECOM | MDS1 and EVI1 complex locus | -0.00571505 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00571283 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00571171 |
| GPX2 | glutathione peroxidase 2 | -0.00570891 |
| PCDH17 | protocadherin 17 | -0.00570607 |
| HAL | histidine ammonia-lyase | -0.00569832 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00569584 |
| INSL3 | insulin-like 3 (Leydig cell) | -0.00566783 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.00566361 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00565806 |
| JMJD6 | jumonji domain containing 6 | -0.00563979 |
| JUNB | jun B proto-oncogene | -0.00562902 |
| HOXB7 | homeobox B7 | -0.00562011 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 | -0.00560878 |
| MAP1A | microtubule-associated protein 1A | -0.00560074 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00559135 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00559037 |
| FOXD1 | forkhead box D1 | -0.005584 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00558312 |
| AIP | aryl hydrocarbon receptor interacting protein | -0.00557322 |
| CORO2B | coronin, actin binding protein, 2B | -0.00556902 |
| FAM117A | family with sequence similarity 117, member A | -0.00556591 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00556321 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00555946 |
| ELANE | elastase, neutrophil expressed | -0.00554364 |
| NFASC | neurofascin | -0.00552577 |
| MCL1 | myeloid cell leukemia 1 | -0.00551388 |
| PDZD2 | PDZ domain containing 2 | -0.00551009 |
| RGS17 | regulator of G-protein signaling 17 | -0.00550563 |
| CAVIN3 | caveolae associated protein 3 | -0.005504 |
| BRD2 | bromodomain containing 2 | -0.00550123 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00550051 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00550027 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00549235 |
| GOLGA8H | golgin A8 family, member H | -0.00548883 |
| PMM2 | phosphomannomutase 2 | -0.00548688 |
| ANGPTL4 | angiopoietin-like 4 | -0.00548364 |
| GPX7 | glutathione peroxidase 7 | -0.00547707 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00546982 |
| JAM3 | junctional adhesion molecule 3 | -0.00546712 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00545855 |
| FMOD | fibromodulin | -0.0054571 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00545479 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0054499 |
| CRP | C-reactive protein, pentraxin-related | -0.00543402 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00543102 |
| ITM2A | integral membrane protein 2A | -0.00543006 |
| NLGN4X | neuroligin 4, X-linked | -0.00542893 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00542357 |
| ZG16 | zymogen granule protein 16 | -0.00542346 |
| SLIT1 | slit homolog 1 (Drosophila) | -0.0054139 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.00541269 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0053899 |
| ELMO1 | engulfment and cell motility 1 | -0.00537863 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.00535967 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.00532976 |
| ESM1 | endothelial cell-specific molecule 1 | -0.00532349 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00531993 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00531853 |
| PRSS8 | protease, serine, 8 | -0.00530093 |
| OPHN1 | oligophrenin 1 | -0.00529273 |
| PRSS3 | protease, serine, 3 | -0.00528923 |
| ADAM23 | ADAM metallopeptidase domain 23 | -0.00528083 |
| SORBS3 | sorbin and SH3 domain containing 3 | -0.00527173 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00526631 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.00525765 |
| NAV3 | neuron navigator 3 | -0.00525666 |
| MVP | major vault protein | -0.00525101 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00525032 |
| CTSG | cathepsin G | -0.00523255 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00520917 |
| DENND1B | DENN/MADD domain containing 1B | -0.00520871 |
| BMP4 | bone morphogenetic protein 4 | -0.00520538 |
| SELENOW | selenoprotein W | -0.00519177 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00519142 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.00518872 |
| EDN3 | endothelin 3 | -0.00518438 |
| RGS16 | regulator of G-protein signaling 16 | -0.0051588 |
| DUSP6 | dual specificity phosphatase 6 | -0.00515662 |
| CES3 | carboxylesterase 3 | -0.00515218 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00514822 |
| MXRA5 | matrix-remodelling associated 5 | -0.00514321 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00513417 |
| SPAG9 | sperm associated antigen 9 | -0.00513325 |
| AREG | amphiregulin | -0.00512829 |
| TEK | TEK tyrosine kinase, endothelial | -0.00511451 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00511245 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.00508996 |
| GPHN | gephyrin | -0.0050855 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.00507894 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.00507809 |
| SLC35G2 | solute carrier family 35, member G2 | -0.00507654 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | -0.00507499 |
