| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | v-akt murine thymoma viral oncogene homolog 1|The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 207) |
| External Link | https://ncbi.nlm.nih.gov/gene/207 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the AKT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.00684919 |
| LTF | lactotransferrin | 0.00603156 |
| PROM1 | prominin 1 | 0.00567296 |
| G0S2 | G0/G1 switch 2 | 0.00546199 |
| OLFM4 | olfactomedin 4 | 0.00529406 |
| GPX3 | glutathione peroxidase 3 | 0.00515591 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0050565 |
| BEX1 | brain expressed, X-linked 1 | 0.00503303 |
| XIC | X chromosome inactivation center | 0.00503301 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00460632 |
| TUBA4A | tubulin, alpha 4a | 0.00450929 |
| PXDN | peroxidasin | 0.00438475 |
| PENK | proenkephalin | 0.00432845 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00425423 |
| BGN | biglycan | 0.00419306 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00413851 |
| SMAD7 | SMAD family member 7 | 0.00412127 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00410636 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0040906 |
| CD9 | CD9 molecule | 0.00406502 |
| MT1E | metallothionein 1E | 0.00403229 |
| PEG3 | paternally expressed 3 | 0.00401137 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00400246 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00399257 |
| TSPO | translocator protein (18kDa) | 0.00397725 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00396523 |
| GOLGA8A | golgin A8 family, member A | 0.00395158 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00391481 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00390852 |
| MT1H | metallothionein 1H | 0.00389258 |
| THBS4 | thrombospondin 4 | 0.00389055 |
| CTSG | cathepsin G | 0.00388648 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00383835 |
| RELN | reelin | 0.00382012 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00378617 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00377622 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00375382 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00371364 |
| LOC283683 | uncharacterized LOC283683 | 0.00369124 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00368345 |
| MMP7 | matrix metallopeptidase 7 | 0.00362825 |
| PEG10 | paternally expressed 10 | 0.00362034 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00358347 |
| APOD | apolipoprotein D | 0.00358166 |
| CRYAB | crystallin, alpha B | 0.00355599 |
| RRAGD | Ras-related GTP binding D | 0.00353725 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00353437 |
| TSPYL5 | TSPY-like 5 | 0.00351839 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00350967 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00349289 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00348378 |
| TSPAN8 | tetraspanin 8 | 0.00348018 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00344549 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00339275 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00338893 |
| RGS4 | regulator of G-protein signaling 4 | 0.00338571 |
| AZU1 | azurocidin 1 | 0.00337461 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00335081 |
| PLBD1 | phospholipase B domain containing 1 | 0.00334588 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00333519 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00332175 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00331594 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00331408 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00330246 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00329208 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00328781 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00327749 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | 0.0032734 |
| MT1G | metallothionein 1G | 0.00323293 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00323182 |
| ALB | albumin | 0.00322952 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00322461 |
| KRT14 | keratin 14, type I | 0.00322154 |
| TEX10 | testis expressed 10 | 0.00321461 |
| SCG5 | secretogranin V | 0.00321362 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00321344 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00320676 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00319503 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.0031916 |
| GOLM1 | golgi membrane protein 1 | 0.00318161 |
| MT1F | metallothionein 1F | 0.00317213 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00316696 |
| CRP | C-reactive protein, pentraxin-related | 0.00316362 |
| ABHD3 | abhydrolase domain containing 3 | 0.00313761 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0031295 |
| JMJD6 | jumonji domain containing 6 | 0.00310681 |
| RIN2 | Ras and Rab interactor 2 | 0.00309489 |
| PCNA | proliferating cell nuclear antigen | 0.00308435 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00305473 |
| FN1 | fibronectin 1 | 0.0030516 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00304774 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00304472 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 0.00304116 |
| REEP1 | receptor accessory protein 1 | 0.00302662 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0030086 |
| S100P | S100 calcium binding protein P | 0.00299762 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00299523 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00295223 |
| GSPT2 | G1 to S phase transition 2 | 0.00295121 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00294655 |
| NKX2-2 | NK2 homeobox 2 | 0.00294259 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00293856 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00293463 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00289062 |
| ORM1 | orosomucoid 1 | 0.00289035 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.0028877 |
| NFIB | nuclear factor I/B | 0.00288635 |
| CFB | complement factor B | 0.00288375 |
| FGL1 | fibrinogen-like 1 | 0.00282908 |
| DACH1 | dachshund family transcription factor 1 | 0.00280533 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00280409 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00279945 |
| DCX | doublecortin | 0.00277584 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00277485 |
| CAB39 | calcium binding protein 39 | 0.00276268 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00274242 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00273462 |
| DGKZ | diacylglycerol kinase, zeta | 0.00273159 |
| SYT11 | synaptotagmin XI | 0.00273141 |
| GYG1 | glycogenin 1 | 0.00270969 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00270783 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0027052 |
| NOTCH2NL | notch 2 N-terminal like | 0.00269754 |
| LPIN1 | lipin 1 | 0.00269674 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00269423 |
| GGT5 | gamma-glutamyltransferase 5 | 0.0026869 |
| PKM | pyruvate kinase, muscle | 0.00266687 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.0026596 |
| GRN | granulin | 0.0026592 |
| CAMP | cathelicidin antimicrobial peptide | 0.00265823 |
| GRAMD1C | GRAM domain containing 1C | 0.00264938 |
| CCND2 | cyclin D2 | 0.00264495 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00264066 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00263991 |
| MT1X | metallothionein 1X | 0.0026223 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.0026199 |
| MTF2 | metal response element binding transcription factor 2 | 0.0026189 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.00261613 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00261149 |
| CDO1 | cysteine dioxygenase type 1 | 0.00260726 |
| MMP9 | matrix metallopeptidase 9 | 0.00260673 |
| RGS5 | regulator of G-protein signaling 5 | 0.00259914 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00259513 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00258763 |
| MYO6 | myosin VI | 0.00258632 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00258602 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00258315 |
| MPO | myeloperoxidase | 0.00257916 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.00257564 |
| KLHL21 | kelch-like family member 21 | 0.00257285 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0025715 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00256784 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00256742 |
| TGFA | transforming growth factor, alpha | 0.00254889 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00254564 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00254473 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00253894 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00253815 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00253154 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00252921 |
| DCLK1 | doublecortin-like kinase 1 | 0.00252399 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00251233 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00251002 |
| BMP2 | bone morphogenetic protein 2 | 0.00250624 |
| TSPAN12 | tetraspanin 12 | 0.00249907 |
| KLF2 | Kruppel-like factor 2 | 0.00249268 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0024925 |
| ATP13A3 | ATPase type 13A3 | 0.00248318 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.00248256 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00247967 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00247611 |
| PLK2 | polo-like kinase 2 | 0.00247303 |
| TSC22D4 | TSC22 domain family, member 4 | 0.0024546 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 0.00244316 |
| TAGLN | transgelin | 0.00244313 |
| BIN1 | bridging integrator 1 | 0.00244042 |
| FAM222B | family with sequence similarity 222, member B | 0.00243733 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00243671 |
| GLA | galactosidase, alpha | 0.00243413 |
| ECM1 | extracellular matrix protein 1 | 0.00241987 |
| ZNF83 | zinc finger protein 83 | 0.00240849 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00240514 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00240307 |
| MXRA7 | matrix-remodelling associated 7 | 0.00240016 |
| INSIG1 | insulin induced gene 1 | 0.00239393 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00239224 |
| MT2A | metallothionein 2A | 0.00239086 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | 0.00239028 |
| BSPRY | B-box and SPRY domain containing | 0.00238816 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.00238226 |
| KRT5 | keratin 5, type II | 0.00237908 |
| SOD3 | superoxide dismutase 3, extracellular | 0.00237553 |
| FRMD4A | FERM domain containing 4A | 0.00236991 |
| ETV5 | ets variant 5 | 0.00236729 |
| ADAM23 | ADAM metallopeptidase domain 23 | 0.00236512 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00236063 |
| MAP2 | microtubule-associated protein 2 | 0.00236046 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00235753 |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like | 0.00235704 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00234978 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.0023427 |
| FGB | fibrinogen beta chain | 0.00234136 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00233993 |
| HTRA1 | HtrA serine peptidase 1 | 0.0023333 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00233291 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00232813 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00232548 |
| NPY | neuropeptide Y | 0.00232286 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00232143 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00232109 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00231667 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00231428 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00231089 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00230991 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00230642 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00230294 |
| HOMER1 | homer scaffolding protein 1 | 0.00230138 |
| BMP4 | bone morphogenetic protein 4 | 0.00229888 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00229697 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.0022924 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00228817 |
| SGCE | sarcoglycan, epsilon | 0.00228747 |
| TTR | transthyretin | 0.00227754 |
| HIP1R | huntingtin interacting protein 1 related | 0.00227138 |
| PFKM | phosphofructokinase, muscle | 0.00227057 |
| C1R | complement component 1, r subcomponent | 0.00226876 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00226871 |
| THBS2 | thrombospondin 2 | 0.00226789 |
| STAG2 | stromal antigen 2 | 0.00226766 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.00226065 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.0022545 |
| GLS | glutaminase | 0.00225337 |
| PRSS3 | protease, serine, 3 | 0.002251 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00224598 |
| KRT15 | keratin 15, type I | 0.00224573 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00224276 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.00224226 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.00224177 |
| KRT23 | keratin 23, type I | 0.00224062 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00223702 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00223518 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | 0.00223058 |
| DEFB1 | defensin, beta 1 | 0.00222922 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00222557 |
| KLK5 | kallikrein-related peptidase 5 | 0.00222477 |
| METTL7A | methyltransferase like 7A | 0.00222323 |
| ANXA5 | annexin A5 | 0.00221901 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00221881 |
| ABHD2 | abhydrolase domain containing 2 | 0.00221768 |
| PCDH9 | protocadherin 9 | 0.00219798 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00973586 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00653031 |
| RGCC | regulator of cell cycle | -0.00631531 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00626523 |
| TFF1 | trefoil factor 1 | -0.00620098 |
| CD99 | CD99 molecule | -0.00612901 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00584729 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.00568695 |
| SELENBP1 | selenium binding protein 1 | -0.00566054 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00559631 |
| ZNF395 | zinc finger protein 395 | -0.00522646 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00499292 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00493429 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00471837 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00453498 |
| MAGEA3 | melanoma antigen family A3 | -0.00442504 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00419677 |
| HBB | hemoglobin, beta | -0.00418676 |
| NEBL | nebulette | -0.00418315 |
| NTS | neurotensin | -0.00417312 |
| MAP7 | microtubule-associated protein 7 | -0.00414657 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0040888 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00404552 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00403408 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.004012 |
| PRAME | preferentially expressed antigen in melanoma | -0.00397593 |
| MMP10 | matrix metallopeptidase 10 | -0.00396943 |
| NPR3 | natriuretic peptide receptor 3 | -0.00393124 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00387145 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00386194 |
| FOXF1 | forkhead box F1 | -0.00383619 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00381948 |
| FZD5 | frizzled class receptor 5 | -0.00380091 |
| MMP12 | matrix metallopeptidase 12 | -0.00377756 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00376545 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00369355 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00368561 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00368091 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0036756 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00360751 |
| PLEK2 | pleckstrin 2 | -0.00360505 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00360458 |
| NELL2 | NEL-like 2 (chicken) | -0.00358366 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00352931 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00352914 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.00347812 |
| TMEM14B | transmembrane protein 14B | -0.00347316 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00347278 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00345177 |
| ODC1 | ornithine decarboxylase 1 | -0.00343338 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0034038 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00338018 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00334919 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00334504 |
| INHBB | inhibin, beta B | -0.00334289 |
| ADM | adrenomedullin | -0.00331637 |
| CTTN | cortactin | -0.00331006 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.0033057 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00329215 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00329005 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00328752 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -0.00328106 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00327386 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00327213 |
| BTG3 | BTG family, member 3 | -0.00322468 |
| EMX2 | empty spiracles homeobox 2 | -0.00322309 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00322012 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00319235 |
| HOXB7 | homeobox B7 | -0.00319188 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -0.00318343 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00317763 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00317103 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00316712 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.00315948 |
| CD2 | CD2 molecule | -0.00315164 |
| COPA | coatomer protein complex, subunit alpha | -0.00315075 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00314439 |
| IL7R | interleukin 7 receptor | -0.003135 |
| PBK | PDZ binding kinase | -0.00312814 |
| ANOS1 | anosmin 1 | -0.00312504 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00309009 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00308941 |
| RHOA | ras homolog family member A | -0.00306782 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00306469 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00305484 |
| KRT20 | keratin 20, type I | -0.0030546 |
| CHN1 | chimerin 1 | -0.00303339 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00302404 |
| STC1 | stanniocalcin 1 | -0.0029885 |
| VEGFA | vascular endothelial growth factor A | -0.00298551 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00298465 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00296518 |
| CD83 | CD83 molecule | -0.00293921 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00293434 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | -0.0029277 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00291718 |
| ACTB | actin, beta | -0.00291295 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00291237 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00291047 |
| SNX11 | sorting nexin 11 | -0.00286899 |
| COL5A2 | collagen, type V, alpha 2 | -0.00286852 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00286678 |
| COG7 | component of oligomeric golgi complex 7 | -0.00286125 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00285667 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00284221 |
| HLA-F | major histocompatibility complex, class I, F | -0.0028383 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00283287 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00281816 |
| CD86 | CD86 molecule | -0.00281638 |
| BMP7 | bone morphogenetic protein 7 | -0.00281345 |
| HNMT | histamine N-methyltransferase | -0.00280797 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.0027992 |
| HOXB6 | homeobox B6 | -0.00276317 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00275224 |
| USP18 | ubiquitin specific peptidase 18 | -0.00275181 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00274453 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.00274408 |
| IL10RB | interleukin 10 receptor, beta | -0.00273583 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00272449 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00271766 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00271319 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00270876 |
| ZNF652 | zinc finger protein 652 | -0.00270387 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00269505 |
| TPM4 | tropomyosin 4 | -0.00268985 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00268463 |
| FOXF2 | forkhead box F2 | -0.00267808 |
| CYTIP | cytohesin 1 interacting protein | -0.00267726 |
| KRT1 | keratin 1, type II | -0.00267698 |
| MED6 | mediator complex subunit 6 | -0.00266991 |
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 | -0.00266984 |
| SORD | sorbitol dehydrogenase | -0.00266292 |
| TKTL1 | transketolase-like 1 | -0.00266215 |
| KYNU | kynureninase | -0.00264729 |
| SLC2A4RG | SLC2A4 regulator | -0.00264419 |
| CHKB | choline kinase beta | -0.00264162 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00263747 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00262996 |
| CD1E | CD1e molecule | -0.00262949 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00261431 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0026091 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00260885 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00260422 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00260398 |
| MYRF | myelin regulatory factor | -0.00260214 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.0026009 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00259745 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00259648 |
| CST1 | cystatin SN | -0.00259509 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00257455 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00256757 |
| MAGEA12 | melanoma antigen family A12 | -0.00256677 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00255716 |
| ACP3 | acid phosphatase 3 | -0.00254679 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00253953 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -0.00253702 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00253348 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00252905 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00252525 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00251647 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00251632 |
| MAPKAPK5-AS1 | MAPKAPK5 antisense RNA 1 | -0.00251095 |
| ZFP36 | ZFP36 ring finger protein | -0.00250768 |
| AUTS2 | autism susceptibility candidate 2 | -0.00250636 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00250557 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00250278 |
| CA9 | carbonic anhydrase IX | -0.0024982 |
| TMPRSS2 | transmembrane protease, serine 2 | -0.00248743 |
| MOCOS | molybdenum cofactor sulfurase | -0.00248616 |
| PRDX2 | peroxiredoxin 2 | -0.00248154 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00247913 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.00247647 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.00247256 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00247217 |
| MYL9 | myosin, light chain 9, regulatory | -0.0024698 |
| GCH1 | GTP cyclohydrolase 1 | -0.00246842 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00246809 |
| MYO1D | myosin ID | -0.00246472 |
| DAZAP2 | DAZ associated protein 2 | -0.00246004 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -0.00244864 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00244396 |
| CLCA1 | chloride channel accessory 1 | -0.00244358 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -0.00244195 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -0.00243716 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00243176 |
| EPB42 | erythrocyte membrane protein band 4.2 | -0.00241683 |
| CD8A | CD8a molecule | -0.00241675 |
| COLEC12 | collectin sub-family member 12 | -0.00241389 |
| KRT81 | keratin 81, type II | -0.00241354 |
| PRF1 | perforin 1 (pore forming protein) | -0.00239714 |
| MTARC2 | mitochondrial amidoxime reducing component 2 | -0.0023876 |
| C19ORF53 | chromosome 19 open reading frame 53 | -0.00238628 |
| GPM6B | glycoprotein M6B | -0.0023833 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00238294 |
| CCL11 | chemokine (C-C motif) ligand 11 | -0.00238265 |
| PRDX6 | peroxiredoxin 6 | -0.00238194 |
| BLVRB | biliverdin reductase B | -0.00238076 |
| KHNYN | KH and NYN domain containing | -0.00237747 |
| GPR18 | G protein-coupled receptor 18 | -0.00237314 |
| CEP170B | centrosomal protein 170B | -0.00237002 |
| POPDC3 | popeye domain containing 3 | -0.00236873 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00236185 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00235063 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00234899 |
| ELAVL1 | ELAV like RNA binding protein 1 | -0.00234621 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00234457 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00233446 |
| CYBRD1 | cytochrome b reductase 1 | -0.0023331 |
| CREM | cAMP responsive element modulator | -0.00233284 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00232076 |
| HDDC2 | HD domain containing 2 | -0.00231094 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.00230794 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00230761 |
| SMYD2 | SET and MYND domain containing 2 | -0.00230734 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00230365 |
| SLAMF7 | SLAM family member 7 | -0.00230247 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0023 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00229954 |
| NKX3-1 | NK3 homeobox 1 | -0.00229152 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00229059 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00228807 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00228512 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.00228276 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00227938 |
| CBX1 | chromobox homolog 1 | -0.00227736 |
| GUCY2C | guanylate cyclase 2C | -0.00227576 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | -0.0022753 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00227396 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00226962 |
| IL2RA | interleukin 2 receptor, alpha | -0.00226161 |
| TESK1 | testis-specific kinase 1 | -0.00226016 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.00225731 |
| HCCS | holocytochrome c synthase | -0.00225707 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00225284 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00224719 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00224424 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | -0.00224188 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00223908 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00223568 |
| TRAF1 | TNF receptor-associated factor 1 | -0.00223527 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00223156 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00222792 |
| HPCAL1 | hippocalcin-like 1 | -0.00222502 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00221939 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00221443 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.0022108 |
| RHOH | ras homolog family member H | -0.00221072 |
| PADI3 | peptidyl arginine deiminase, type III | -0.00221068 |
| CD1C | CD1c molecule | -0.00220787 |
