AKT2 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description v-akt murine thymoma viral oncogene homolog 2|This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 208)
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100 substrates of the kinase AKT2 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
MYO1F myosin IF
ARHGAP11A Rho GTPase activating protein 11A
WNK1 WNK lysine deficient protein kinase 1
HEXIM1 hexamethylene bis-acetamide inducible 1
OSBPL5 oxysterol binding protein-like 5
RRAD Ras-related associated with diabetes
TP53RK TP53 regulating kinase
TRIM17 tripartite motif containing 17
BTK Bruton agammaglobulinemia tyrosine kinase
PRICKLE3 prickle homolog 3 (Drosophila)
C11ORF30 chromosome 11 open reading frame 30
PLXNB1 plexin B1
SCAF1 SR-related CTD-associated factor 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
MYO1E myosin IE
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
UBE2O ubiquitin-conjugating enzyme E2O
KIF2A kinesin heavy chain member 2A
BRCA1 breast cancer 1, early onset
KIF27 kinesin family member 27
KIF23 kinesin family member 23
MKI67 marker of proliferation Ki-67
TRA2A transformer 2 alpha homolog (Drosophila)
PDE3A phosphodiesterase 3A, cGMP-inhibited
WDR81 WD repeat domain 81
RNF217 ring finger protein 217
CREBZF CREB/ATF bZIP transcription factor
PRRT3 proline-rich transmembrane protein 3
CCDC120 coiled-coil domain containing 120
THOC5 THO complex 5
ZNF687 zinc finger protein 687
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
AIM1 absent in melanoma 1
FRMD4B FERM domain containing 4B
GATA3 GATA binding protein 3
RPS6 ribosomal protein S6
FLJ22184
DMXL1 Dmx-like 1
S1PR1 sphingosine-1-phosphate receptor 1
SEPT1 septin 1
BAHD1 bromo adjacent homology domain containing 1
TRPS1 trichorhinophalangeal syndrome I
MVD mevalonate (diphospho) decarboxylase
P3H3 prolyl 3-hydroxylase 3
SOX9 SRY (sex determining region Y)-box 9
SRSF2 serine/arginine-rich splicing factor 2
NEO1 neogenin 1
GAS7 growth arrest-specific 7
DEPDC5 DEP domain containing 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
URI1 URI1, prefoldin-like chaperone
RARA retinoic acid receptor, alpha
HBP1 HMG-box transcription factor 1
GRK7 G protein-coupled receptor kinase 7
GPR15 G protein-coupled receptor 15
MAP3K11 mitogen-activated protein kinase kinase kinase 11
RARG retinoic acid receptor, gamma
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
NOP2 NOP2 nucleolar protein
SECISBP2L SECIS binding protein 2-like
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
ANKRD33B ankyrin repeat domain 33B
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
CEP128 centrosomal protein 128kDa
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
PYGO2 pygopus family PHD finger 2
CDCA2 cell division cycle associated 2
CDCA7 cell division cycle associated 7
ZFP91 ZFP91 zinc finger protein
CHKB choline kinase beta
DSP desmoplakin
CHERP calcium homeostasis endoplasmic reticulum protein
AEBP2 AE binding protein 2
FAM214B family with sequence similarity 214, member B
SRRM1 serine/arginine repetitive matrix 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
EI24 etoposide induced 2.4
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
TWIST1 twist family bHLH transcription factor 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
SETD2 SET domain containing 2
DGKZ diacylglycerol kinase, zeta
INTS3 integrator complex subunit 3
REM2 RAS (RAD and GEM)-like GTP binding 2
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
UBR5 ubiquitin protein ligase E3 component n-recognin 5
SRRM2 serine/arginine repetitive matrix 2
ALPK3 alpha-kinase 3
PIANP PILR alpha associated neural protein
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2
MEPCE methylphosphate capping enzyme
KANK1 KN motif and ankyrin repeat domains 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
DGAT1 diacylglycerol O-acyltransferase 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LARP4B La ribonucleoprotein domain family, member 4B