ALG10 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ALG10, alpha-1,2-glucosyltransferase|This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 84920)
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Genes

305 genes differentially expressed following the ALG10 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CSAG1 chondrosarcoma associated gene 1 2.44918
PRDM7 PR domain containing 7 2.44918
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.44918
PCDH8 protocadherin 8 2.44918
LRRC10B leucine rich repeat containing 10B 2.44918
CRIP1 cysteine-rich protein 1 (intestinal) 2.44918
PLK5 polo-like kinase 5 2.44918
CLEC6A C-type lectin domain family 6, member A 2.44918
CRYGB crystallin, gamma B 2.44918
BAAT bile acid CoA:amino acid N-acyltransferase 2.44918
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.44918
POSTN periostin, osteoblast specific factor 2.44918
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.44918
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.44918
LBP lipopolysaccharide binding protein 2.44918
VRK2 vaccinia related kinase 2 2.44918
SCAF8 SR-related CTD-associated factor 8 2.44918
REN renin 2.44918
PTGFR prostaglandin F receptor (FP) 2.44918
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.44918
KRT72 keratin 72, type II 2.44918
TRPC5OS TRPC5 opposite strand 2.44918
KHDC1L KH homology domain containing 1-like 2.44918
DNAH2 dynein, axonemal, heavy chain 2 2.44918
FOXC1 forkhead box C1 2.44918
IQCB1 IQ motif containing B1 2.44918
TPRX1 tetra-peptide repeat homeobox 1 2.44918
FXYD3 FXYD domain containing ion transport regulator 3 2.44918
KRTAP13-4 keratin associated protein 13-4 2.44918
PITX3 paired-like homeodomain 3 2.44918
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.44918
NWD2 NACHT and WD repeat domain containing 2 2.44918
LY6K lymphocyte antigen 6 complex, locus K 2.44918
NBEAL1 neurobeachin-like 1 2.44918
LGALS2 lectin, galactoside-binding, soluble, 2 2.44918
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.44918
SP6 Sp6 transcription factor 2.44918
ACY3 aminoacylase 3 2.44918
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 2.44918
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.44918
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.44918
KCNU1 potassium channel, subfamily U, member 1 2.44918
TMEM81 transmembrane protein 81 2.44918
SSMEM1 serine-rich single-pass membrane protein 1 2.44918
GPR84 G protein-coupled receptor 84 2.44918
TUBA3D tubulin, alpha 3d 2.44918
SLC68A1 solute carrier family 68 member 1 2.44918
POMC proopiomelanocortin 2.44918
KLHL33 kelch-like family member 33 2.44918
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.44918
PCDHA3 protocadherin alpha 3 2.44918
PXDNL peroxidasin-like 2.44918
CAPN14 calpain 14 2.44918
C3ORF80 chromosome 3 open reading frame 80 2.44918
ANXA10 annexin A10 2.44918
CD79A CD79a molecule, immunoglobulin-associated alpha 2.44918
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 2.44918
CCR3 chemokine (C-C motif) receptor 3 2.44918
INSRR insulin receptor-related receptor 2.44918
FAM186A family with sequence similarity 186, member A 2.44918
TLR2 toll-like receptor 2 2.44918
TACSTD2 tumor-associated calcium signal transducer 2 2.44918
SCRT2 scratch family zinc finger 2 2.44918
CXCL14 chemokine (C-X-C motif) ligand 14 2.44918
SLFN14 schlafen family member 14 2.44918
RAB44 RAB44, member RAS oncogene family 2.44918
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 2.44918
MYO18B myosin XVIIIB 2.44918
C8ORF48 chromosome 8 open reading frame 48 2.44918
TMEM100 transmembrane protein 100 2.44918
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.44918
FOXR1 forkhead box R1 2.44918
LRRN4CL LRRN4 C-terminal like 2.44918
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.44918
FETUB fetuin B 2.44918
GPR151 G protein-coupled receptor 151 2.44918
PXDC1 PX domain containing 1 2.44918
FOXA2 forkhead box A2 2.44918
TMEM229A transmembrane protein 229A 2.44918
FLG filaggrin 2.44918
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.44918
KLHL34 kelch-like family member 34 2.44918
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 2.44918
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.44918
AKAP14 A kinase (PRKA) anchor protein 14 2.44918
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.44918
LRRC72 leucine rich repeat containing 72 2.44918
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.44918
ZDHHC11B zinc finger, DHHC-type containing 11B 2.44918
PRRT1B proline rich transmembrane protein 1B 2.44918
ZCCHC18 zinc finger, CCHC domain containing 18 2.44918
KLK14 kallikrein-related peptidase 14 2.44918
ZNF705D zinc finger protein 705D 2.44918
SPMIP3 sperm microtubule inner protein 3 2.44918
FBXL22 F-box and leucine-rich repeat protein 22 2.44918
C8B complement component 8, beta polypeptide 2.44918
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.44918
VWA3A von Willebrand factor A domain containing 3A 2.44918
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.44918
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.44918
BTNL8 butyrophilin-like 8 2.44918
CIBAR1 CBY1 interacting BAR domain containing 1 2.44918
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 2.44918
TMEM204 transmembrane protein 204 2.44918
TMEM202 transmembrane protein 202 2.44918
APOC4 apolipoprotein C-IV 2.44918
CYS1 cystin 1 2.44918
SPEF1 sperm flagellar 1 2.44918
SPMIP8 sperm microtubule inner protein 8 2.44918
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.44918
HPGDS hematopoietic prostaglandin D synthase 2.44918
LAMB1 laminin, beta 1 2.44918
SPMIP10 sperm microtubule inner protein 10 2.44918
ZNF835 zinc finger protein 835 2.44918
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 2.44918
GOLGA8M golgin A8 family, member M 2.44918
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 2.44918
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.44918
GPR150 G protein-coupled receptor 150 2.44918
SIGLEC15 sialic acid binding Ig-like lectin 15 2.44918
TMPPE transmembrane protein with metallophosphoesterase domain 2.44918
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.44918
GCGR glucagon receptor 2.44918
EFCC1 EF-hand and coiled-coil domain containing 1 2.44918
CIMIP7 ciliary microtubule inner protein 7 2.44918
DRC5 dynein regulatory complex subunit 5 2.44918
IGIP IgA-inducing protein 2.44918
ADGRA1 adhesion G protein-coupled receptor A1 2.44918
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.44918
SRGN serglycin 2.44918
VTCN1 V-set domain containing T cell activation inhibitor 1 2.44918
POTEF POTE ankyrin domain family, member F 2.44918
MST1 macrophage stimulating 1 2.44918
CARNS1 carnosine synthase 1 2.44918
LTB4R2 leukotriene B4 receptor 2 2.44918
EPX eosinophil peroxidase 2.44918
MC5R melanocortin 5 receptor 2.44918
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 2.44918
HHIPL2 HHIP-like 2 2.44918
TMPRSS4 transmembrane protease, serine 4 2.44918
PADI1 peptidyl arginine deiminase, type I 2.44918
OR10G7 olfactory receptor, family 10, subfamily G, member 7 2.44918
TTC34 tetratricopeptide repeat domain 34 2.44918
RGPD5 RANBP2-like and GRIP domain containing 5 2.44918
ACSL5 acyl-CoA synthetase long-chain family member 5 2.44918
CGA glycoprotein hormones, alpha polypeptide 2.44918
CD80 CD80 molecule 2.44918
PKM pyruvate kinase, muscle 2.44918
RERGL RERG/RAS-like 2.44918
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.44918
ZNF679 zinc finger protein 679 2.44918
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.44918
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.44918
DKKL1 dickkopf-like 1 2.44918
KASH5 KASH domain containing 5 2.44918
LRTM2 leucine-rich repeats and transmembrane domains 2 2.44918
NIM1K NIM1 serine/threonine protein kinase 2.44918
POF1B premature ovarian failure, 1B 2.44918
TMEM132D transmembrane protein 132D 2.44918
BIN1 bridging integrator 1 2.44918
RAD51AP2 RAD51 associated protein 2 2.44918
AURKC aurora kinase C 2.44918
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 2.44918
GPR12 G protein-coupled receptor 12 2.44918
SKIC2 SKI2 subunit of superkiller complex 2.44918
KPNA7 karyopherin alpha 7 (importin alpha 8) 2.44918
SHOX2 short stature homeobox 2 2.44918
CMKLR2 chemerin chemokine-like receptor 2 2.41873
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.41873
TMEM50A transmembrane protein 50A 2.41873
YLPM1 YLP motif containing 1 2.4098
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.39325
DEFB131B defensin beta 131B 2.39305
CACHD1 cache domain containing 1 2.39305
PTPRB protein tyrosine phosphatase, receptor type, B 2.36984
RPL8 ribosomal protein L8 2.35776
CDH24 cadherin 24, type 2 2.34553
ERICH1 glutamate-rich 1 2.31881
KANSL1L KAT8 regulatory NSL complex subunit 1-like 2.31836
EFNA1 ephrin-A1 2.31836
EFCAB14 EF-hand calcium binding domain 14 2.31464
IRF2BP1 interferon regulatory factor 2 binding protein 1 2.2887
DPY19L3 dpy-19-like 3 (C. elegans) 2.27612
AGBL5 ATP/GTP binding protein-like 5 2.25826
WDR83OS WD repeat domain 83 opposite strand 2.25826
FADS6 fatty acid desaturase 6 2.25826
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 2.25826
ATXN7 ataxin 7 2.21246
CHMP4A charged multivesicular body protein 4A 2.20754
SLC39A10 solute carrier family 39 (zinc transporter), member 10 2.18648
SLC35D4 solute carrier family 35 member D4 2.18648
RPP40 ribonuclease P/MRP 40kDa subunit 2.16848
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.16845
SEC11A SEC11 homolog A (S. cerevisiae) 2.14927
EMC1 ER membrane protein complex subunit 1 2.14465
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 2.12969
H3C12 H3 clustered histone 12 2.11905
PYY peptide YY 2.11905
USP9X ubiquitin specific peptidase 9, X-linked 2.08205
ORC2 origin recognition complex, subunit 2 2.08205
TRIM22 tripartite motif containing 22 2.08176
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like 2.08176
GARS1 glycyl-tRNA synthetase 1 2.07941
RICTOR RPTOR independent companion of MTOR, complex 2 2.07941
ENTREP1 endosomal transmembrane epsin interactor 1 2.07069
ZNF106 zinc finger protein 106 2.07069
KLK10 kallikrein-related peptidase 10 2.05035
SENP5 SUMO1/sentrin specific peptidase 5 2.03357
SENP1 SUMO1/sentrin specific peptidase 1 2.03026
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 2.0279
TMEM135 transmembrane protein 135 2.02679
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2.02416
CCDC200 coiled-coil domain containing 200 2.01853
ATXN7L2 ataxin 7-like 2 2.01801
CFAP58 cilia and flagella associated protein 58 2.01382
RNF7 ring finger protein 7 2.00564

decreased expression

Symbol Name Standardized Value
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.44918
CLPSL1 colipase-like 1 -2.44918
TMEM248 transmembrane protein 248 -2.44918
LZTR1 leucine-zipper-like transcription regulator 1 -2.44918
PKD1L1 polycystic kidney disease 1 like 1 -2.44918
FAM53A family with sequence similarity 53, member A -2.44918
ATXN10 ataxin 10 -2.44918
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) -2.44918
RPL38 ribosomal protein L38 -2.44918
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -2.44918
MSRB1 methionine sulfoxide reductase B1 -2.44918
CCNYL1 cyclin Y-like 1 -2.44918
ZNF525 zinc finger protein 525 -2.44918
DUSP5 dual specificity phosphatase 5 -2.44918
PNPLA5 patatin-like phospholipase domain containing 5 -2.44918
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -2.44918
DPF3 D4, zinc and double PHD fingers, family 3 -2.44918
PHF23 PHD finger protein 23 -2.44918
ZNF284 zinc finger protein 284 -2.44918
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -2.44918
NRXN3 neurexin 3 -2.41873
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.4
RHOF ras homolog family member F (in filopodia) -2.39298
TSPAN10 tetraspanin 10 -2.36984
FAM43A family with sequence similarity 43, member A -2.36984
DUT deoxyuridine triphosphatase -2.34447
LTB4R leukotriene B4 receptor -2.33997
ZFX zinc finger protein, X-linked -2.3324
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -2.31962
PTCH2 patched 2 -2.31881
CCDC85B coiled-coil domain containing 85B -2.31464
XRRA1 X-ray radiation resistance associated 1 -2.30055
TEX261 testis expressed 261 -2.2716
VEGFD vascular endothelial growth factor D -2.25826
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -2.25826
SLC23A3 solute carrier family 23, member 3 -2.25826
MEI1 meiosis inhibitor 1 -2.25826
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -2.25826
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -2.25826
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) -2.25826
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.25826
SIX1 SIX homeobox 1 -2.25826
OVOL1 ovo-like zinc finger 1 -2.25826
INSYN1 inhibitory synaptic factor 1 -2.25826
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 -2.25826
REP15 RAB15 effector protein -2.25826
MYZAP myocardial zonula adherens protein -2.25826
YPEL4 yippee-like 4 (Drosophila) -2.25826
DGLUCY D-glutamate cyclase -2.25826
SMIM36 small integral membrane protein 36 -2.25826
SUSD2 sushi domain containing 2 -2.25826
EBF3 early B-cell factor 3 -2.25826
CD101 CD101 molecule -2.25826
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -2.25826
LRRC36 leucine rich repeat containing 36 -2.25826
ANKRD7 ankyrin repeat domain 7 -2.25826
ZNF470 zinc finger protein 470 -2.25826
MDH1B malate dehydrogenase 1B, NAD (soluble) -2.25826
RHOJ ras homolog family member J -2.25826
TTPA tocopherol (alpha) transfer protein -2.25826
BCAS1 breast carcinoma amplified sequence 1 -2.25826
ASCL5 achaete-scute family bHLH transcription factor 5 -2.25826
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -2.24464
HIST1H2BF histone cluster 1, H2bf -2.23871
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 -2.23404
OSBPL3 oxysterol binding protein-like 3 -2.22571
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -2.22571
SPATA17 spermatogenesis associated 17 -2.22212
BRI3BP BRI3 binding protein -2.21217
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1 -2.19602
ARMC5 armadillo repeat containing 5 -2.1839
ZNF605 zinc finger protein 605 -2.14439
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -2.13284
SYT7 synaptotagmin VII -2.11905
CA10 carbonic anhydrase X -2.08205
SNX13 sorting nexin 13 -2.08176
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 -2.08176
DNAL4 dynein, axonemal, light chain 4 -2.08176
CCDC183 coiled-coil domain containing 183 -2.08176
KDM3A lysine (K)-specific demethylase 3A -2.08112
ZNF266 zinc finger protein 266 -2.08112
MAMDC2 MAM domain containing 2 -2.07069
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.06858
LY6G5B lymphocyte antigen 6 complex, locus G5B -2.0413
LYPD1 LY6/PLAUR domain containing 1 -2.03436
AEN apoptosis enhancing nuclease -2.02679
ITM2C integral membrane protein 2C -2.02322
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.01853
TRIM35 tripartite motif containing 35 -2.00564