ALKBH2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description alkB, alkylation repair homolog 2 (E. coli)|The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 121642)
External Link https://ncbi.nlm.nih.gov/gene/121642
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Genes

499 genes differentially expressed following the ALKBH2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 0.0216922
PEG10 paternally expressed 10 0.0146845
TFPI2 tissue factor pathway inhibitor 2 0.014029
DLK1 delta-like 1 homolog (Drosophila) 0.0139171
SRGN serglycin 0.0137884
HSPA1A heat shock 70kDa protein 1A 0.0131718
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0126727
RB1 retinoblastoma 1 0.0125809
SCG5 secretogranin V 0.0117481
RGS1 regulator of G-protein signaling 1 0.0116687
STC2 stanniocalcin 2 0.0115855
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0114172
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0109163
ANPEP alanyl (membrane) aminopeptidase 0.01086
PENK proenkephalin 0.0107874
MLPH melanophilin 0.0106598
ADI1 acireductone dioxygenase 1 0.0106123
FN1 fibronectin 1 0.010528
TIMP1 TIMP metallopeptidase inhibitor 1 0.0104019
SGCE sarcoglycan, epsilon 0.0103341
MAGEA3 melanoma antigen family A3 0.0102941
ISG15 ISG15 ubiquitin-like modifier 0.00996888
ZIC1 Zic family member 1 0.00984004
NIBAN1 niban apoptosis regulator 1 0.00983646
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00965141
NAV2 neuron navigator 2 0.00956828
ATG101 autophagy related 101 0.00947554
CADM1 cell adhesion molecule 1 0.00938515
MET MET proto-oncogene, receptor tyrosine kinase 0.00936705
PDGFC platelet derived growth factor C 0.00935424
C1QA complement component 1, q subcomponent, A chain 0.00931995
CYBA cytochrome b-245, alpha polypeptide 0.00930359
TRIB3 tribbles pseudokinase 3 0.00930029
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00929909
BST2 bone marrow stromal cell antigen 2 0.00927307
NID2 nidogen 2 (osteonidogen) 0.00922294
ATF3 activating transcription factor 3 0.00920409
TWIST1 twist family bHLH transcription factor 1 0.00912094
FTH1 ferritin, heavy polypeptide 1 0.00903689
NOTCH2 notch 2 0.00902831
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00898552
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.00888666
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.0088257
DVL1 dishevelled segment polarity protein 1 0.00879149
TNS3 tensin 3 0.00878625
MGLL monoglyceride lipase 0.00878198
IFI6 interferon, alpha-inducible protein 6 0.00869478
NOTCH2NL notch 2 N-terminal like 0.00865524
SOX9 SRY (sex determining region Y)-box 9 0.00864963
IL6 interleukin 6 0.00861154
BTBD3 BTB (POZ) domain containing 3 0.00856991
AHR aryl hydrocarbon receptor 0.00856703
IFRD1 interferon-related developmental regulator 1 0.00854457
ZFP36L1 ZFP36 ring finger protein-like 1 0.00852114
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.00850395
SYNM synemin, intermediate filament protein 0.00849255
CXCL8 chemokine (C-X-C motif) ligand 8 0.00849048
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00844768
PROM1 prominin 1 0.0084466
ZNF331 zinc finger protein 331 0.0084094
LOXL2 lysyl oxidase-like 2 0.00831854
VNN1 vanin 1 0.00830414
TSC22D1 TSC22 domain family, member 1 0.00829989
CLGN calmegin 0.00819271
GREM1 gremlin 1, DAN family BMP antagonist 0.00817724
CNPY3 canopy FGF signaling regulator 3 0.00815683
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00814196
PFKM phosphofructokinase, muscle 0.00813888
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00812162
RRBP1 ribosome binding protein 1 0.00811759
PLXNB2 plexin B2 0.00809389
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00808902
PLK2 polo-like kinase 2 0.00803706
MPRIP myosin phosphatase Rho interacting protein 0.00798681
EFNB2 ephrin-B2 0.00797086
TOMM34 translocase of outer mitochondrial membrane 34 0.00791404
SPRY2 sprouty homolog 2 (Drosophila) 0.00791236
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00785695
OXTR oxytocin receptor 0.00779765
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00779152
NAXD NAD(P)HX dehydratase 0.00771161
PLXNC1 plexin C1 0.00765857
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00765116
SIK1 salt-inducible kinase 1 0.00761048
MMP2 matrix metallopeptidase 2 0.00759158
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.00756188
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00754877
CSRP2 cysteine and glycine-rich protein 2 0.00754677
MBNL1 muscleblind-like splicing regulator 1 0.00750834
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00750247
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.00749601
COL6A2 collagen, type VI, alpha 2 0.00746311
IFITM3 interferon induced transmembrane protein 3 0.00745051
RFTN1 raftlin, lipid raft linker 1 0.00736876
LSP1 lymphocyte-specific protein 1 0.00735861
QKI QKI, KH domain containing, RNA binding 0.00735739
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.007337
COL9A2 collagen, type IX, alpha 2 0.00732423
DYNLL1 dynein, light chain, LC8-type 1 0.00728637
BICC1 BicC family RNA binding protein 1 0.00726381
DDRGK1 DDRGK domain containing 1 0.00726238
EXT1 exostosin glycosyltransferase 1 0.00726028
APOB apolipoprotein B 0.00725574
TPCN1 two pore segment channel 1 0.00722806
TSPO translocator protein (18kDa) 0.0072223
KLK11 kallikrein-related peptidase 11 0.00720625
TGFBI transforming growth factor, beta-induced, 68kDa 0.00719489
IL6ST interleukin 6 signal transducer 0.00718977
APOLD1 apolipoprotein L domain containing 1 0.00716959
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00715758
HMOX1 heme oxygenase 1 0.00715725
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00706052
IGFBP4 insulin-like growth factor binding protein 4 0.0070291
PDLIM4 PDZ and LIM domain 4 0.00702772
WWTR1 WW domain containing transcription regulator 1 0.00700024
RTN2 reticulon 2 0.00699899
PLIN2 perilipin 2 0.00699569
AMPD2 adenosine monophosphate deaminase 2 0.00698192
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.00695159
RIN2 Ras and Rab interactor 2 0.00693066
ZSCAN18 zinc finger and SCAN domain containing 18 0.00689847
AMPD3 adenosine monophosphate deaminase 3 0.00689466
FOXD1 forkhead box D1 0.00688477
MMD monocyte to macrophage differentiation-associated 0.00688277
MT1M metallothionein 1M 0.00686638
UBL3 ubiquitin-like 3 0.0068509
ODC1 ornithine decarboxylase 1 0.00684826
PFDN2 prefoldin subunit 2 0.00683914
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00682437
SGK1 serum/glucocorticoid regulated kinase 1 0.00681701
MMP19 matrix metallopeptidase 19 0.00680343
TM4SF1 transmembrane 4 L six family member 1 0.00679611
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.006782
RHOBTB3 Rho-related BTB domain containing 3 0.00677972
MRC2 mannose receptor, C type 2 0.00677155
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00676569
VCAM1 vascular cell adhesion molecule 1 0.00674789
LEPR leptin receptor 0.00672149
GBAP1 glucosidase, beta, acid pseudogene 1 0.0067148
DCT dopachrome tautomerase 0.00670448
NFE2L2 nuclear factor, erythroid 2-like 2 0.00669729
C5AR1 complement component 5a receptor 1 0.00667624
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.00666677
LYPD1 LY6/PLAUR domain containing 1 0.00664731
IL13RA2 interleukin 13 receptor, alpha 2 0.00664004
RBPMS RNA binding protein with multiple splicing 0.00663808
TFRC transferrin receptor 0.00662919
KAZN kazrin, periplakin interacting protein 0.00662646
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.00661371
DGKD diacylglycerol kinase, delta 130kDa 0.00659153
IFITM2 interferon induced transmembrane protein 2 0.00658955
POR P450 (cytochrome) oxidoreductase 0.0065895
LAPTM4B lysosomal protein transmembrane 4 beta 0.00658619
TNIK TRAF2 and NCK interacting kinase 0.00658026
DOCK9 dedicator of cytokinesis 9 0.00657648
GLS glutaminase 0.00656479
INHBB inhibin, beta B 0.00655174
LAGE3 L antigen family, member 3 0.00652614
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00652044
GOLM1 golgi membrane protein 1 0.00650878
SOCS2 suppressor of cytokine signaling 2 0.0065034
C1QB complement component 1, q subcomponent, B chain 0.00649221
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00648235
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00646973
ITPKB inositol-trisphosphate 3-kinase B 0.00645905
SST somatostatin 0.00645771
TES testin LIM domain protein 0.0064038
JMJD6 jumonji domain containing 6 0.00638943
TRIB1 tribbles pseudokinase 1 0.00635816
COL6A1 collagen, type VI, alpha 1 0.00635615
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.00634787
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.00634786
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.00634115
EZR ezrin 0.00633641
AHSG alpha-2-HS-glycoprotein 0.00632112
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.0063161
XIC X chromosome inactivation center 0.00630662
SDC4 syndecan 4 0.00629701
SOCS3 suppressor of cytokine signaling 3 0.00628331
PMP22 peripheral myelin protein 22 0.00627223
H1-0 H1.0 linker histone 0.00625867
KAT2B K(lysine) acetyltransferase 2B 0.00625046
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00623872
TDO2 tryptophan 2,3-dioxygenase 0.00623665
ANXA3 annexin A3 0.00623534
STXBP6 syntaxin binding protein 6 (amisyn) 0.00623027
SEC24C SEC24 family member C 0.00622935
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.006229
FGG fibrinogen gamma chain 0.00621986
ACD adrenocortical dysplasia homolog (mouse) 0.00621707
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00620738
L1CAM L1 cell adhesion molecule 0.00620575
SIRT1 sirtuin 1 0.00620026
ICAM2 intercellular adhesion molecule 2 0.00618942
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00618619
IRF9 interferon regulatory factor 9 0.00618497
TMX4 thioredoxin-related transmembrane protein 4 0.00618194
WIPF1 WAS/WASL interacting protein family, member 1 0.00615612
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00615541
PXDN peroxidasin 0.00614146
CLIP2 CAP-GLY domain containing linker protein 2 0.00613926
NGRN neugrin, neurite outgrowth associated 0.00613825
SDF4 stromal cell derived factor 4 0.00612258
LEPROTL1 leptin receptor overlapping transcript-like 1 0.00611685
SUCO SUN domain containing ossification factor 0.00610866
PFN2 profilin 2 0.00609691
CTSA cathepsin A 0.00609517
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00609106
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00607888
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.0060624
DUSP1 dual specificity phosphatase 1 0.00606061
MRPL20 mitochondrial ribosomal protein L20 0.00604541
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00603838
IGSF3 immunoglobulin superfamily, member 3 0.00602473
TSPAN4 tetraspanin 4 0.00600627
DAP death-associated protein 0.00599221
CDK11A cyclin-dependent kinase 11A 0.00599091
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00598946
PLP1 proteolipid protein 1 0.0059884
CREM cAMP responsive element modulator 0.00596716
PDZRN3 PDZ domain containing ring finger 3 0.00596499
FAM50A family with sequence similarity 50, member A 0.00596173
MUC16 mucin 16, cell surface associated 0.00594703
PHC2 polyhomeotic homolog 2 (Drosophila) 0.00594371
PXDC1 PX domain containing 1 0.00593705
MALT1 MALT1 paracaspase 0.00591783
WNT5A wingless-type MMTV integration site family, member 5A 0.0059122
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.00589816
BMP2 bone morphogenetic protein 2 0.00589698
AK1 adenylate kinase 1 0.00589579
NRIP1 nuclear receptor interacting protein 1 0.00589567
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00589501
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.005892
ZFHX4 zinc finger homeobox 4 0.00587714
EHBP1L1 EH domain binding protein 1-like 1 0.0058728
RIN3 Ras and Rab interactor 3 0.00587126
WWC3 WWC family member 3 0.00586508
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00585502
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00584379
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00584004
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00583978
WNT5B wingless-type MMTV integration site family, member 5B 0.00582741
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00582498
VNN2 vanin 2 0.0058082
TBL2 transducin (beta)-like 2 0.00580288
ADAP2 ArfGAP with dual PH domains 2 0.00579694
APMAP adipocyte plasma membrane associated protein 0.00578387
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00578266
MAGED2 melanoma antigen family D2 0.00577818

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0160828
CXCL14 chemokine (C-X-C motif) ligand 14 -0.015758
PLN phospholamban -0.0145378
S100A8 S100 calcium binding protein A8 -0.0141131
AQP3 aquaporin 3 (Gill blood group) -0.0135046
HOPX HOP homeobox -0.0130033
CRYBG1 crystallin beta-gamma domain containing 1 -0.0129323
ASPN asporin -0.0127753
SPRR1B small proline-rich protein 1B -0.0126726
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0122809
VSNL1 visinin-like 1 -0.012276
KRT6A keratin 6A, type II -0.0119132
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.0117675
SNAP25 synaptosomal-associated protein, 25kDa -0.0116441
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0115917
CAST calpastatin -0.011433
PGAM1 phosphoglycerate mutase 1 (brain) -0.0111848
CXADR coxsackie virus and adenovirus receptor -0.011142
S100A9 S100 calcium binding protein A9 -0.0108462
TLCD3A TLC domain containing 3A -0.0106628
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0105619
S100A2 S100 calcium binding protein A2 -0.0105195
PALLD palladin, cytoskeletal associated protein -0.0105011
RAB25 RAB25, member RAS oncogene family -0.0104711
NRN1 neuritin 1 -0.0104698
SEPP1 selenoprotein P, plasma, 1 -0.0104079
HOXC6 homeobox C6 -0.0103081
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0101591
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00999712
TXN thioredoxin -0.00985892
MMP7 matrix metallopeptidase 7 -0.00982309
GLUL glutamate-ammonia ligase -0.00980724
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00972169
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00965069
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00962405
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0095849
TACSTD2 tumor-associated calcium signal transducer 2 -0.00956503
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00937697
KDM5D lysine (K)-specific demethylase 5D -0.00930756
SYT1 synaptotagmin I -0.00925135
CST1 cystatin SN -0.00919306
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00918768
KRT6B keratin 6B, type II -0.0091002
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00909027
NPY1R neuropeptide Y receptor Y1 -0.0090197
CD99 CD99 molecule -0.0089834
ABHD17B abhydrolase domain containing 17B -0.00894628
PPL periplakin -0.00891709
ESRP1 epithelial splicing regulatory protein 1 -0.00889402
MMP12 matrix metallopeptidase 12 -0.00888373
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00881665
S100A7 S100 calcium binding protein A7 -0.00880262
CSTA cystatin A (stefin A) -0.00880181
CALB1 calbindin 1, 28kDa -0.00877662
OLFM1 olfactomedin 1 -0.00874252
DPEP1 dipeptidase 1 (renal) -0.00862894
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00858901
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00855829
MGP matrix Gla protein -0.00846433
TOX3 TOX high mobility group box family member 3 -0.00844319
KRT16 keratin 16, type I -0.0083031
CD27 CD27 molecule -0.00826613
STOM stomatin -0.00822642
RBBP4 retinoblastoma binding protein 4 -0.00819698
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00810469
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00806699
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00801347
ACOX2 acyl-CoA oxidase 2, branched chain -0.00798375
COL10A1 collagen, type X, alpha 1 -0.00794752
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00792453
CPA3 carboxypeptidase A3 (mast cell) -0.00791952
SPRR1A small proline-rich protein 1A -0.00789225
CALD1 caldesmon 1 -0.00783358
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00773631
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00771311
YBX3 Y box binding protein 3 -0.00766777
OPHN1 oligophrenin 1 -0.00764394
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00764071
SORD sorbitol dehydrogenase -0.00759027
SDC1 syndecan 1 -0.00756235
HEATR1 HEAT repeat containing 1 -0.00756211
CCL19 chemokine (C-C motif) ligand 19 -0.00752305
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00748904
KRT5 keratin 5, type II -0.00748594
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00748041
TGFBR3 transforming growth factor, beta receptor III -0.00747978
CLDN8 claudin 8 -0.00743777
NUSAP1 nucleolar and spindle associated protein 1 -0.00743511
UMOD uromodulin -0.00738902
SFRP4 secreted frizzled-related protein 4 -0.00737554
SH3YL1 SH3 and SYLF domain containing 1 -0.00737423
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00735475
RPL14 ribosomal protein L14 -0.00735446
CNOT8 CCR4-NOT transcription complex, subunit 8 -0.00733147
ADAM28 ADAM metallopeptidase domain 28 -0.00729954
NELL2 NEL-like 2 (chicken) -0.00729624
KRT15 keratin 15, type I -0.00729055
CD2 CD2 molecule -0.00728469
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00728029
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.00726519
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00723901
AOC1 amine oxidase, copper containing 1 -0.00723024
EPCAM epithelial cell adhesion molecule -0.00722747
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00722681
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00721966
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00721321
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -0.0071353
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00710812
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00710687
MXRA5 matrix-remodelling associated 5 -0.00706853
CCL14 chemokine (C-C motif) ligand 14 -0.0070616
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.00705135
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00704852
MYH11 myosin, heavy chain 11, smooth muscle -0.00703857
RHOA ras homolog family member A -0.00703115
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00702526
STX3 syntaxin 3 -0.00701695
EXOC5 exocyst complex component 5 -0.00701151
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00699004
PPAP2A phosphatidic acid phosphatase type 2A -0.00694803
CD8A CD8a molecule -0.00693866
TMEM176B transmembrane protein 176B -0.0069277
CLDND1 claudin domain containing 1 -0.0069092
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00689834
IRF6 interferon regulatory factor 6 -0.0068963
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.00689521
AHCY adenosylhomocysteinase -0.00689306
EMCN endomucin -0.00689281
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -0.0068561
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00684414
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00681961
NDRG1 N-myc downstream regulated 1 -0.00681589
AHNAK2 AHNAK nucleoprotein 2 -0.00678756
OLFM4 olfactomedin 4 -0.00672594
KRCC1 lysine-rich coiled-coil 1 -0.00667744
CLIP1 CAP-GLY domain containing linker protein 1 -0.00667033
UBXN7 UBX domain protein 7 -0.00665781
PLAU plasminogen activator, urokinase -0.00665173
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00664662
BHMT betaine--homocysteine S-methyltransferase -0.00661566
CD52 CD52 molecule -0.00661348
PTPRO protein tyrosine phosphatase, receptor type, O -0.00659628
SET SET nuclear proto-oncogene -0.00659398
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00658592
CTSV cathepsin V -0.00657764
GMDS GDP-mannose 4,6-dehydratase -0.00656742
LEFTY1 left-right determination factor 1 -0.00655284
ZNF204P zinc finger protein 204, pseudogene -0.0065342
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00650754
CHGB chromogranin B -0.00649932
CLEC11A C-type lectin domain family 11, member A -0.00649354
ITGA6 integrin, alpha 6 -0.00648221
LSR lipolysis stimulated lipoprotein receptor -0.00647457
RHCG Rh family, C glycoprotein -0.00644187
COL5A2 collagen, type V, alpha 2 -0.00643713
PODXL podocalyxin-like -0.00641978
ELANE elastase, neutrophil expressed -0.00640881
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.00640825
CES1 carboxylesterase 1 -0.00638529
HLA-DOB major histocompatibility complex, class II, DO beta -0.0063643
RAB23 RAB23, member RAS oncogene family -0.00636381
F2R coagulation factor II (thrombin) receptor -0.0063566
NCK1 NCK adaptor protein 1 -0.00635296
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.0063526
FERMT1 fermitin family member 1 -0.00634995
EAF2 ELL associated factor 2 -0.00632514
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00632099
FZD5 frizzled class receptor 5 -0.00626925
NRGN neurogranin (protein kinase C substrate, RC3) -0.00625833
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00625494
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00623455
DSG3 desmoglein 3 -0.00621545
SMIM8 small integral membrane protein 8 -0.00619971
ZNF277 zinc finger protein 277 -0.00619405
MPZL2 myelin protein zero-like 2 -0.006192
PARM1 prostate androgen-regulated mucin-like protein 1 -0.0061834
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.00617044
GPR87 G protein-coupled receptor 87 -0.00616688
INSR insulin receptor -0.00614796
ECI2 enoyl-CoA delta isomerase 2 -0.00614178
CLCA4 chloride channel accessory 4 -0.00614032
FABP7 fatty acid binding protein 7, brain -0.00610867
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00610851
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00610771
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00610062
NFYB nuclear transcription factor Y, beta -0.00607895
CCND2 cyclin D2 -0.00606974
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00606959
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00605118
GTPBP8 GTP-binding protein 8 (putative) -0.00604788
PAH phenylalanine hydroxylase -0.00604371
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00604063
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00603482
MPO myeloperoxidase -0.00602897
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00602175
FOXC1 forkhead box C1 -0.00599388
NFYA nuclear transcription factor Y, alpha -0.00598784
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00596541
ALDOB aldolase B, fructose-bisphosphate -0.00596264
MME membrane metallo-endopeptidase -0.00593738
CFD complement factor D (adipsin) -0.00593572
CLCA2 chloride channel accessory 2 -0.00593542
FRZB frizzled-related protein -0.00592405
SPRR3 small proline-rich protein 3 -0.00590966
CAV1 caveolin 1, caveolae protein, 22kDa -0.00590176
THY1 Thy-1 cell surface antigen -0.00589279
BSPRY B-box and SPRY domain containing -0.00589016
GDE1 glycerophosphodiester phosphodiesterase 1 -0.00587938
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00587779
PTH1R parathyroid hormone 1 receptor -0.00584663
GCH1 GTP cyclohydrolase 1 -0.00584463
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 -0.00584281
AGPS alkylglycerone phosphate synthase -0.0058354
MMP9 matrix metallopeptidase 9 -0.00583512
CD200 CD200 molecule -0.00582903
RHOH ras homolog family member H -0.00582406
ABHD4 abhydrolase domain containing 4 -0.0057703
ZNF271P zinc finger protein 271, pseudogene -0.00575613
MEN1 multiple endocrine neoplasia I -0.00574016
CD1A CD1a molecule -0.00573161
GAL galanin/GMAP prepropeptide -0.00572634
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.00572369
ATG5 autophagy related 5 -0.00570362
APOL2 apolipoprotein L, 2 -0.00570177
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00569052
TWSG1 twisted gastrulation BMP signaling modulator 1 -0.00568999
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -0.00567925
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0056775
TNF tumor necrosis factor -0.00566103
MRPL19 mitochondrial ribosomal protein L19 -0.00565867
NOTCH3 notch 3 -0.0056585
DMAC2L distal membrane arm assembly component 2 like -0.00564545
CUBN cubilin (intrinsic factor-cobalamin receptor) -0.00562812
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00562623
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -0.00562538
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00562022
WDR61 WD repeat domain 61 -0.00561894
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.00561254
FGFBP1 fibroblast growth factor binding protein 1 -0.00561096
AZU1 azurocidin 1 -0.0055635
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00555266
FGD6 FYVE, RhoGEF and PH domain containing 6 -0.00555106
PPA2 pyrophosphatase (inorganic) 2 -0.00554491
NPR3 natriuretic peptide receptor 3 -0.0055448
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00552532
NEFM neurofilament, medium polypeptide -0.00552044
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00551434
NOX1 NADPH oxidase 1 -0.00550442
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00548777
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.00547911