AMG-900 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

15 genes differentially expressed following the AMG-900 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MT2A metallothionein 2A 4.34405
MT1X metallothionein 1X 3.69612
MT1HL1 metallothionein 1H-like 1 3.59973
HMG20B high mobility group 20B 3.53943
MT1H metallothionein 1H 3.47542
MAGEA10 melanoma antigen family A10 3.19525
MT1E metallothionein 1E 3.04541
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.00987

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -5.1137
MAP7 microtubule-associated protein 7 -4.53974
COPS7A COP9 signalosome subunit 7A -3.87375
PARD6B par-6 family cell polarity regulator beta -3.62356
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.05332
GMEB1 glucocorticoid modulatory element binding protein 1 -3.05309
ULK4 unc-51 like kinase 4 -3.01151