AMOT Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description angiomotin|This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 154796)
External Link http://www.ncbi.nlm.nih.gov/gene/154796
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Genes

318 interacting proteins for AMOT from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACAD11 acyl-CoA dehydrogenase family, member 11
ACTA1 actin, alpha 1, skeletal muscle
ACTB actin, beta
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHCYL1 adenosylhomocysteinase-like 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALMS1 Alstrom syndrome protein 1
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
ANAPC1 anaphase promoting complex subunit 1
ANKRD26 ankyrin repeat domain 26
ANKRD28 ankyrin repeat domain 28
ANKRD44 ankyrin repeat domain 44
ANKRD52 ankyrin repeat domain 52
APP amyloid beta (A4) precursor protein
ARHGAP17 Rho GTPase activating protein 17
ATAD3A ATPase family, AAA domain containing 3A
ATAD3B ATPase family, AAA domain containing 3B
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATPIF1 ATPase inhibitory factor 1
AURKB aurora kinase B
BAG3 BCL2-associated athanogene 3
BAIAP2L1 BAI1-associated protein 2-like 1
BASP1 brain abundant, membrane attached signal protein 1
BMS1 BMS1 ribosome biogenesis factor
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB3 BUB3 mitotic checkpoint protein
C14ORF169 chromosome 14 open reading frame 169
CA2 carbonic anhydrase II
CAPN3 calpain 3, (p94)
CCDC138 coiled-coil domain containing 138
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CDC27 cell division cycle 27
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPJ centromere protein J
CEP152 centrosomal protein 152kDa
CEP170B centrosomal protein 170B
CEP192 centrosomal protein 192kDa
CEP250 centrosomal protein 250kDa
CEP72 centrosomal protein 72kDa
CEP76 centrosomal protein 76kDa
CEP85 centrosomal protein 85kDa
CGN cingulin
CLIP1 CAP-GLY domain containing linker protein 1
CNTROB centrobin, centrosomal BRCA2 interacting protein
COPS5 COP9 signalosome subunit 5
CPEB4 cytoplasmic polyadenylation element binding protein 4
CPNE3 copine III
CPVL carboxypeptidase, vitellogenic-like
CS citrate synthase
CSPP1 centrosome and spindle pole associated protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL3 cullin 3
CYLD cylindromatosis (turban tumor syndrome)
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLG1 discs, large homolog 1 (Drosophila)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DOCK6 dedicator of cytokinesis 6
DOCK7 dedicator of cytokinesis 7
DOCK8 dedicator of cytokinesis 8
DST dystonin
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
EIF4B eukaryotic translation initiation factor 4B
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERP44 endoplasmic reticulum protein 44
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FASN fatty acid synthase
FBXL16 F-box and leucine-rich repeat protein 16
FBXO45 F-box protein 45
FBXO6 F-box protein 6
FBXW11 F-box and WD repeat domain containing 11
FECH ferrochelatase
FLCN folliculin
FLOT1 flotillin 1
FNIP1 folliculin interacting protein 1
FOXK1 forkhead box K1
FOXK2 forkhead box K2
FUBP3 far upstream element (FUSE) binding protein 3
GBAS glioblastoma amplified sequence
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GLMN glomulin, FKBP associated protein
GRIP1 glutamate receptor interacting protein 1
GTSE1 G-2 and S-phase expressed 1
GYG1 glycogenin 1
GYS1 glycogen synthase 1 (muscle)
HAUS2 HAUS augmin-like complex, subunit 2
HDAC6 histone deacetylase 6
HELZ helicase with zinc finger
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HNF4A hepatocyte nuclear factor 4, alpha
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA4 heat shock 70kDa protein 4
HSPA4L heat shock 70kDa protein 4-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
INADL InaD-like (Drosophila)
IPO11 importin 11
ITCH itchy E3 ubiquitin protein ligase
IVNS1ABP influenza virus NS1A binding protein
KCTD6 potassium channel tetramerization domain containing 6
KEAP1 kelch-like ECH-associated protein 1
KIAA0368 KIAA0368
KIAA0753 KIAA0753
KIAA0930 KIAA0930
KIAA1462 KIAA1462
KIAA1549 KIAA1549
KIAA1671 KIAA1671
KIF1BP KIF1 binding protein
KIF7 kinesin family member 7
KIRREL kin of IRRE like (Drosophila)
KPNA3 karyopherin alpha 3 (importin alpha 4)
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LIMD1 LIM domains containing 1
LIN7A lin-7 homolog A (C. elegans)
LIN7C lin-7 homolog C (C. elegans)
LNX2 ligand of numb-protein X 2
LONP2 lon peptidase 2, peroxisomal
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC47 leucine rich repeat containing 47
LZTS2 leucine zipper, putative tumor suppressor 2
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK3 mitogen-activated protein kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MCMBP minichromosome maintenance complex binding protein
MIA3 melanoma inhibitory activity family, member 3
MIPOL1 mirror-image polydactyly 1
MLF2 myeloid leukemia factor 2
MLH1 mutL homolog 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOB1A MOB kinase activator 1A
MOB2 MOB kinase activator 2
MPDZ multiple PDZ domain protein
MPHOSPH9 M-phase phosphoprotein 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MRPS14 mitochondrial ribosomal protein S14
MRPS21 mitochondrial ribosomal protein S21
MRPS26 mitochondrial ribosomal protein S26
MRPS31 mitochondrial ribosomal protein S31
MRPS34 mitochondrial ribosomal protein S34
MRPS35 mitochondrial ribosomal protein S35
MYBPC1 myosin binding protein C, slow type
MYBPC2 myosin binding protein C, fast type
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYH9 myosin, heavy chain 9, non-muscle
MYO6 myosin VI
MYOM3 myomesin 3
NCKAP5L NCK-associated protein 5-like
NCKIPSD NCK interacting protein with SH3 domain
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NET1 neuroepithelial cell transforming 1
NF2 neurofibromin 2 (merlin)
NIN ninein (GSK3B interacting protein)
NINL ninein-like
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NME7 NME/NM23 family member 7
NOTCH1 notch 1
NOTCH2 notch 2
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP153 nucleoporin 153kDa
NYNRIN NYN domain and retroviral integrase containing
OFD1 oral-facial-digital syndrome 1
OSBPL10 oxysterol binding protein-like 10
OSBPL9 oxysterol binding protein-like 9
OTUD1 OTU deubiquitinase 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARD3 par-3 family cell polarity regulator
PARK2 parkin RBR E3 ubiquitin protein ligase
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PCM1 pericentriolar material 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PDZD11 PDZ domain containing 11
PGAM5 phosphoglycerate mutase family member 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIBF1 progesterone immunomodulatory binding factor 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKN2 protein kinase N2
PKP4 plakophilin 4
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLG plasminogen
PLRG1 pleiotropic regulator 1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP6C protein phosphatase 6, catalytic subunit
PPP6R1 protein phosphatase 6, regulatory subunit 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCI protein kinase C, iota
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUM1 pumilio RNA-binding family member 1
RAB35 RAB35, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RADIL Ras association and DIL domains
RAE1 ribonucleic acid export 1
RANBP9 RAN binding protein 9
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RB1CC1 RB1-inducible coiled-coil 1
RBM15 RNA binding motif protein 15
RIF1 replication timing regulatory factor 1
SART3 squamous cell carcinoma antigen recognized by T cells 3
SAV1 salvador family WW domain containing protein 1
SCLT1 sodium channel and clathrin linker 1
SDCCAG3 serologically defined colon cancer antigen 3
SEC16A SEC16 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SH3PXD2A SH3 and PX domains 2A
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMC1A structural maintenance of chromosomes 1A
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOCS6 suppressor of cytokine signaling 6
SORBS1 sorbin and SH3 domain containing 1
SPICE1 spindle and centriole associated protein 1
SPRYD3 SPRY domain containing 3
SRRM2 serine/arginine repetitive matrix 2
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STIM1 stromal interaction molecule 1
STIM2 stromal interaction molecule 2
STK3 serine/threonine kinase 3
STK38L serine/threonine kinase 38 like
STK4 serine/threonine kinase 4
STOML2 stomatin (EPB72)-like 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STXBP4 syntaxin binding protein 4
TBK1 TANK-binding kinase 1
TBKBP1 TBK1 binding protein 1
TCEAL1 transcription elongation factor A (SII)-like 1
TCEAL2 transcription elongation factor A (SII)-like 2
TCEAL4 transcription elongation factor A (SII)-like 4
TCHP trichoplein, keratin filament binding
TEAD3 TEA domain family member 3
TEX10 testis expressed 10
THRA thyroid hormone receptor, alpha
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TMOD1 tropomodulin 1
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TRIP12 thyroid hormone receptor interactor 12
TTN titin
TUBGCP2 tubulin, gamma complex associated protein 2
UBC ubiquitin C
UIMC1 ubiquitin interaction motif containing 1
ULK1 unc-51 like autophagy activating kinase 1
UNK unkempt family zinc finger
USP11 ubiquitin specific peptidase 11
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP42 ubiquitin specific peptidase 42
USP54 ubiquitin specific peptidase 54
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTRN utrophin
VASP vasodilator-stimulated phosphoprotein
VPRBP Vpr (HIV-1) binding protein
WBP2 WW domain binding protein 2
WDR18 WD repeat domain 18
WDR6 WD repeat domain 6
WWC1 WW and C2 domain containing 1
WWOX WW domain containing oxidoreductase
WWTR1 WW domain containing transcription regulator 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPR1 xenotropic and polytropic retrovirus receptor 1
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YTHDC2 YTH domain containing 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF24 zinc finger protein 24