AP-1 adaptor complex Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). (Gene Ontology, GO_0030121)
External Link http://amigo.geneontology.org/amigo/term/GO:0030121
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Genes

12 proteins localized to the AP-1 adaptor complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
AFTPH aftiphilin
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
CLBA1 clathrin binding box of aftiphilin containing 1
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SYNRG synergin, gamma