AP-2 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)|The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 7020)
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Genes

4 target genes of the AP-2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
CHRM3 cholinergic receptor, muscarinic 3
IGF1R insulin-like growth factor 1 receptor
SNORA48 small nucleolar RNA, H/ACA box 48
ZBTB18 zinc finger and BTB domain containing 18